category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 7/43 142/9376 10.7487716999672 FOS/JUN/KLF2/HSP90AA1/PLAT/HSP90AB1/RAC1 7.94526469482386 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 6/43 139/9376 9.41207963861469 FOS/JUN/HSP90AA1/HSPA1A/HSP90AB1/FKBP4 6.78194927155708 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 6/43 142/9376 9.21323288568621 JUNB/FOS/JUND/JUN/SOCS3/RAC1 6.6937980789137 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 5/43 94/9376 11.5982187036121 FOS/JUND/JUN/HSP90AA1/HSP90AB1 7.00947119142582 Human Diseases Infectious disease: viral hsa05162 Measles 5/43 136/9376 8.01641586867305 FOS/JUN/MX1/HSPA1A/OAS1 5.5944580772523 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 7/43 300/9376 5.0877519379845 AREG/FOS/JUND/JUN/HSPA1A/BDNF/RAC1 4.88435419632792 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 6/43 216/9376 6.05684754521964 FOS/JUN/HSP90AA1/HSPA1A/HSP90AB1/RAC1 5.1035013319937 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 6/43 224/9376 5.84053156146179 FOS/JUN/EGR1/B2M/ZFP36/PTEN 4.97700747133296 Organismal Systems Immune system hsa04612 Antigen processing and presentation 4/43 82/9376 10.6364152013613 B2M/HSP90AA1/HSPA1A/HSP90AB1 5.94881316549382 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 4/43 87/9376 10.025126971398 AREG/FOS/JUN/RAC1 5.74034108528583 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 6/43 238/9376 5.49697088137581 FOS/JUN/ISG15/MX1/OAS1/RPS10 4.76971258755153 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 4/43 91/9376 9.58446204957833 FOS/JUN/IFITM1/RAC1 5.58537144302741 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 6/43 248/9376 5.27531882970743 FOS/JUN/RHOB/HSP90AA1/HSP90AB1/RAC1 4.63143704787145 Human Diseases Cancer: specific types hsa05215 Prostate cancer 4/43 106/9376 8.2281702501097 HSP90AA1/PLAT/HSP90AB1/PTEN 5.07984746701067 Organismal Systems Immune system hsa04659 Th17 cell differentiation 4/43 109/9376 8.00170684873053 FOS/JUN/HSP90AA1/HSP90AB1 4.99064667557109 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 4/43 119/9376 7.32929450850107 JUNB/FOS/JUN/SOCS3 4.71631589637835 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 5/43 205/9376 5.31820760068066 JUN/ISG15/B2M/OAS1/RAC1 4.24308111616281 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 4/43 156/9376 5.59093619558736 IFIT1/MX1/OAS1/SOCS3 3.92470780268542 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 4/43 157/9376 5.55532513701674 FOS/JUN/SOCS3/RAC1 3.90693811398043 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 6/43 362/9376 3.61403057946807 AREG/HSP90AA1/BDNF/HSP90AB1/PTEN/RAC1 3.44282862512131 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 3/43 90/9376 7.26821705426357 FOS/JUN/PTEN 4.05564725656097 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 4/43 174/9376 5.01256348569901 HSP90AA1/HSPA1A/HSP90AB1/DNAJA1 3.62630776151432 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 4/43 187/9376 4.66409650540977 JUN/HSP90AA1/OAS1/HSP90AB1 3.43528532557209 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 3/43 99/9376 6.60747004933051 FOS/JUN/RAC1 3.8070625706188 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 3/43 101/9376 6.47662905825466 JUN/EGR1/RAC1 3.75600608529422 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 4/43 196/9376 4.4499288087328 FOS/JUN/ZFP36/RAC1 3.31303528580425 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 3/43 109/9376 6.0012801365479 FOS/JUN/RAC1 3.56479107542011 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 3/43 115/9376 5.68816986855409 FOS/JUND/EGR1 3.43346441325887 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 4/43 214/9376 4.07563573136275 FOS/JUN/B2M/RAC1 3.08927004795538 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 4/43 217/9376 4.01929053691994 FOS/JUN/HSP90AA1/HSP90AB1 3.05435826130229 Organismal Systems Nervous system hsa04722 Neurotrophin signaling pathway 3/43 120/9376 5.45116279069767 JUN/BDNF/RAC1 3.33090050968296 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 3/43 122/9376 5.36179946626001 JUNB/FOS/SOCS3 3.29147147606571 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 4/43 226/9376 3.85923029429924 FOS/JUN/BDNF/RAC1 2.95326244171714 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 4/43 227/9376 3.84222927978691 FOS/JUN/PTEN/RAC1 2.94235084744977 Human Diseases Substance dependence hsa05030 Cocaine addiction 2/43 49/9376 8.89985761746559 JUN/BDNF 3.76318482341348 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 3/43 138/9376 4.74014155712841 FOS/JUN/RAC1 3.00433140115742 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 3/43 140/9376 4.67242524916943 EGR1/KLF2/PLAT 2.97155828766258 Human Diseases Cancer: specific types hsa05224 Breast cancer 3/43 148/9376 4.4198617221873 FOS/JUN/PTEN 2.84639287813722 Human Diseases Substance dependence hsa05031 Amphetamine addiction 2/43 69/9376 6.32018874283788 FOS/JUN 3.01062013178691 Human Diseases Cancer: specific types hsa05211 Renal cell carcinoma 2/43 70/9376 6.22990033222591 JUN/RAC1 2.98105604800449 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 2/43 71/9376 6.14215525712414 FOS/SOCS3 2.95206152041819 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 2/43 71/9376 6.14215525712414 JUN/RAC1 2.95206152041819 Human Diseases Infectious disease: viral hsa05164 Influenza A 3/43 173/9376 3.78115338083076 MX1/OAS1/SOCS3 2.50606605825678 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 3/43 180/9376 3.63410852713178 B2M/OAS1/SOCS3 2.42203083887334 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 2/43 78/9376 5.59093619558736 FOS/JUN 2.76352259962622 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 2/43 78/9376 5.59093619558736 FOS/JUN 2.76352259962622 Environmental Information Processing Signal transduction hsa04012 ErbB signaling pathway 2/43 86/9376 5.07084910762574 AREG/JUN 2.57416040941811 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 2/43 88/9376 4.95560253699789 PLAT/TFPI 2.53047535847439 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 3/43 200/9376 3.2706976744186 FOS/JUN/RAC1 2.2032148169919 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 3/43 203/9376 3.22236224080651 JUN/PTEN/RAC1 2.17278325095492 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 2/43 93/9376 4.68917229307327 FOS/JUN 2.42680829322609 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 2/43 93/9376 4.68917229307327 JUN/EGR1 2.42680829322609 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 2/43 95/9376 4.59045287637699 FOS/JUN 2.3873873068478 Organismal Systems Immune system hsa04666 Fc gamma R-mediated phagocytosis 2/43 98/9376 4.4499288087328 RAC1/MARCKS 2.33026450558102 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 2/43 99/9376 4.40498003288701 FOS/JUN 2.31173272846213 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 2/43 103/9376 4.23391284714382 FOS/JUN 2.23998973004385 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 2/43 109/9376 4.00085342436527 SOCS3/PTEN 2.13893547526914 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 2/43 110/9376 3.96448202959831 BMP2/ID4 2.1227959469428 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 2/43 110/9376 3.96448202959831 HSP90AA1/HSP90AB1 2.1227959469428 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 2/43 122/9376 3.57453297750667 FOS/JUN 1.94277658228055 Environmental Information Processing Signal transduction hsa04071 Sphingolipid signaling pathway 2/43 125/9376 3.48874418604651 PTEN/RAC1 1.90129785213117 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 2/43 130/9376 3.35456171735242 FOS/JUN 1.83490693996285 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 2/43 133/9376 3.27889491169785 KLF2/PTEN 1.79660612419608 Cellular Processes Cell growth and death hsa04210 Apoptosis 2/43 137/9376 3.18316075369207 FOS/JUN 1.74720051321885 Human Diseases Neurodegenerative disease hsa05020 Prion disease 3/43 275/9376 2.37868921775899 EGR1/HSPA1A/RAC1 1.57506108650394 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 2/43 154/9376 2.83177287828451 FOS/JUN 1.55571005611879 Cellular Processes Cell growth and death hsa04218 Cellular senescence 2/43 157/9376 2.77766256850837 ZFP36L1/PTEN 1.52463708600394 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 2/43 157/9376 2.77766256850837 AREG/BMP2 1.52463708600394 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 2/43 163/9376 2.67541732058782 FOS/JUN 1.46462182204651 Cellular Processes Cell growth and death hsa04217 Necroptosis 2/43 168/9376 2.59579180509413 HSP90AA1/HSP90AB1 1.416633309232 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 2/43 170/9376 2.56525307797538 JUN/RAC1 1.39792146968545 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 3/43 323/9376 2.02519979840161 TIMP3/PTEN/MARCKS 1.27269033541473 Human Diseases Endocrine and metabolic disease hsa04930 Type II diabetes mellitus 1/43 47/9376 4.63928748144483 SOCS3 1.6976844825076 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 3/43 333/9376 1.9643829876388 ISG15/MX1/PTEN 1.21625496157607 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 2/43 178/9376 2.44996080480794 JUN/RAC1 1.32564974983897 NA NA hsa03272 Virion - Hepatitis viruses 1/43 48/9376 4.54263565891473 CD9 1.67017536212214 Organismal Systems Development and regeneration hsa04360 Axon guidance 2/43 184/9376 2.37007077856421 RAC1/RND1 1.27396102137451 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 1/43 56/9376 3.8936877076412 HSPA1A 1.47416789867382 NA NA hsa04082 Neuroactive ligand signaling 2/43 199/9376 2.19142222741615 P2RY14/P2RX5 1.1530578679158 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 1/43 59/9376 3.69570358691368 PTEN 1.40983837506968 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 2/43 204/9376 2.13771089831281 TIMP3/RAC1 1.11512669380072 Environmental Information Processing Signal transduction hsa04370 VEGF signaling pathway 1/43 60/9376 3.63410852713178 RAC1 1.3893247822705 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 2/43 205/9376 2.12728304027226 JUN/RAC1 1.10767101146223 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 2/43 205/9376 2.12728304027226 PTEN/RAC1 1.10767101146223 Organismal Systems Aging hsa04213 Longevity regulating pathway - multiple species 1/43 62/9376 3.51687921980495 HSPA1A 1.34958218298459 Human Diseases Cancer: specific types hsa05217 Basal cell carcinoma 1/43 63/9376 3.46105574012551 BMP2 1.33032011062089 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 1/43 66/9376 3.30373502466526 JUN 1.27479069700756 Organismal Systems Immune system hsa04664 Fc epsilon RI signaling pathway 1/43 69/9376 3.16009437141894 RAC1 1.22236708423328 Organismal Systems Endocrine system hsa04920 Adipocytokine signaling pathway 1/43 70/9376 3.11495016611296 SOCS3 1.20552679466374 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 1/43 70/9376 3.11495016611296 RAC1 1.20552679466374 Human Diseases Cancer: overview hsa05230 Central carbon metabolism in cancer 1/43 71/9376 3.07107762856207 PTEN 1.18898560377121 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 2/43 227/9376 1.92111463989345 B2M/RAC1 0.953562212789566 Organismal Systems Immune system hsa04622 RIG-I-like receptor signaling pathway 1/43 72/9376 3.02842377260982 ISG15 1.1727334753866 Genetic Information Processing Information processing in viruses hsa03250 Viral life cycle - HIV-1 1/43 73/9376 2.98693851545078 MX1 1.1567608481129 Human Diseases Cancer: specific types hsa05218 Melanoma 1/43 73/9376 2.98693851545078 PTEN 1.1567608481129 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 2/43 232/9376 1.87971130713713 RGCC/RAC1 0.920927180238819 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 1/43 75/9376 2.90728682170543 PTEN 1.12561805509589 Human Diseases Cancer: specific types hsa05214 Glioma 1/43 76/9376 2.86903304773562 PTEN 1.11043089247274 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 2/43 238/9376 1.83232362712527 BDNF/RAC1 0.882804133257223 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 1/43 77/9376 2.83177287828451 RAC1 1.0954891896029 Metabolism Carbohydrate metabolism hsa00562 Inositol phosphate metabolism 1/43 78/9376 2.79546809779368 PTEN 1.08078536790162 Genetic Information Processing Folding, sorting and degradation hsa03018 RNA degradation 1/43 78/9376 2.79546809779368 BTG2 1.08078536790162 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 1/43 78/9376 2.79546809779368 RAC1 1.08078536790162 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 1/43 80/9376 2.72558139534884 PTEN 1.05206268890512 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 2/43 253/9376 1.72368783895579 JUN/RAC1 0.792048782845739 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 1/43 87/9376 2.50628174284951 TPM4 0.95805532729869 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 1/43 93/9376 2.34458614653663 RAC1 0.884494556542851 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/43 93/9376 2.34458614653663 PTEN 0.884494556542851 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 1/43 97/9376 2.247902181731 FOS 0.838542457373055 Environmental Information Processing Signal transduction hsa04070 Phosphatidylinositol signaling system 1/43 98/9376 2.2249644043664 PTEN 0.827405790191859 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 1/43 99/9376 2.2024900164435 TPM4 0.816402886305459 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 1/43 100/9376 2.18046511627907 ACKR3 0.805530559483441 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 1/43 100/9376 2.18046511627907 CD9 0.805530559483441 Organismal Systems Digestive system hsa04972 Pancreatic secretion 1/43 102/9376 2.13771089831281 RAC1 0.784165428161155 Cellular Processes Transport and catabolism hsa04137 Mitophagy - animal 1/43 105/9376 2.0766334440753 JUN 0.753023376596579 Organismal Systems Immune system hsa04625 C-type lectin receptor signaling pathway 1/43 105/9376 2.0766334440753 JUN 0.753023376596579 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 1/43 105/9376 2.0766334440753 TPM4 0.753023376596579 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 2/43 298/9376 1.4633994068987 BMP2/ACKR3 0.551794985568647 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 1/43 112/9376 1.9468438538206 HSPA1A 0.684222475095789 Organismal Systems Nervous system hsa04725 Cholinergic synapse 1/43 115/9376 1.89605662285136 FOS 0.656242971796147 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 1/43 116/9376 1.87971130713713 RAC1 0.647102247854842 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/43 133/9376 1.63944745584892 RAC1 0.504119434986963 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 1/43 133/9376 1.63944745584892 FOS 0.504119434986963 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 1/43 138/9376 1.58004718570947 SOCS3 0.465932625159225 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 1/43 142/9376 1.53553881428104 SOCS3 0.436464999362867 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 1/43 144/9376 1.51421188630491 ID4 0.422070202389742 Organismal Systems Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes 1/43 154/9376 1.41588643914225 TPM4 0.353209026756071 NA NA hsa04518 Integrin signaling 1/43 154/9376 1.41588643914225 RAC1 0.353209026756071 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 2/43 370/9376 1.17862979258328 P2RY14/P2RX5 0.2379567439821 Cellular Processes Transport and catabolism hsa04145 Phagosome 1/43 155/9376 1.40675168792198 RAC1 0.346589526689471 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 1/43 157/9376 1.38883128425418 RAC1 0.333486572015694 Environmental Information Processing Signal transduction hsa04150 mTOR signaling pathway 1/43 158/9376 1.38004121283485 PTEN 0.327001782523522 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 1/43 168/9376 1.29789590254707 SOCS3 0.264451325595702 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 1/43 169/9376 1.29021604513554 PTEN 0.258413342372804 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 1/43 170/9376 1.28262653898769 PTEN 0.252412668796551 NA NA hsa04519 Cadherin signaling 2/43 404/9376 1.07943817637578 CDH6/RAC1 0.11078591498099 Human Diseases Substance dependence hsa05034 Alcoholism 1/43 191/9376 1.14160477292098 BDNF 0.134203619275847 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/43 193/9376 1.12977467164719 RAC1 0.123647555303114 Cellular Processes Cell motility hsa04814 Motor proteins 1/43 194/9376 1.1239510908655 TPM4 0.118410934088198 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/43 195/9376 1.11818723911747 RAC1 0.113201487228989 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 1/43 201/9376 1.08480851556173 PLAT 0.082498050698747 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 1/43 212/9376 1.02852128126371 RAC1 0.0285104225994505 NA NA hsa04081 Hormone signaling 1/43 219/9376 0.995646171816927 NPR3 -0.00442512934709234 Genetic Information Processing Translation hsa03010 Ribosome 1/43 222/9376 0.982191493819401 RPS10 -0.0182266879206397 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 2/43 480/9376 0.908527131782946 BDNF/RAC1 -0.139644797839721 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 1/43 233/9376 0.935821938317197 TPM4 -0.0673332271764411 Genetic Information Processing Transcription hsa03040 Spliceosome 1/43 243/9376 0.897310747439947 HSPA1A -0.110085630427913 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 1/43 250/9376 0.872186046511628 LAPTM4A -0.139032801440714 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/43 250/9376 0.872186046511628 HSPA1A -0.139032801440714 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 1/43 254/9376 0.858450833180736 P2RX5 -0.155234545625618 NA NA hsa04517 IgSF CAM signaling 1/43 299/9376 0.729252547250525 RAC1 -0.322952044973054 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 1/43 308/9376 0.707943219571127 BDNF -0.353749739670882 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 1/43 368/9376 0.592517694641052 RAC1 -0.541287138800442