category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	2/22	37/9376	23.036855036855	PLCB4/PRKCG	6.51326254975325
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	2/22	53/9376	16.082332761578	PLCB4/PRKCG	5.3398235567109
Organismal Systems	Nervous system	hsa04730	Long-term depression	2/22	60/9376	14.2060606060606	PLCB4/PRKCG	4.97659692775937
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/22	65/9376	13.1132867132867	PLCB4/PRKCG	4.75246369206377
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	2/22	67/9376	12.7218453188602	PLCB4/PRKCG	4.66960524562094
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	2/22	73/9376	11.6762141967621	APOBEC3B/PPIAL4G	4.44084375978617
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	3/22	212/9376	6.03087478559177	FGFR4/PLCB4/PRKCG	3.5930825429387
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	2/22	75/9376	11.3648484848485	PLCB4/PRKCG	4.37045912895923
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	2/22	76/9376	11.2153110047847	PLCB4/PRKCG	4.33625896704529
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	2/22	86/9376	9.91120507399577	PLCB4/PRKCG	4.0260216192947
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	2/22	89/9376	9.57711950970378	PLCB4/PRKCG	3.94273000321574
Human Diseases	Substance dependence	hsa05032	Morphine addiction	2/22	91/9376	9.36663336663337	PDE11A/PRKCG	3.88936566690076
Organismal Systems	Digestive system	hsa04970	Salivary secretion	2/22	93/9376	9.16520039100684	PLCB4/PRKCG	3.83762418628455
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	3/22	254/9376	5.0336435218325	FGFR4/PLCB4/PRKCG	3.16058616309113
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/22	97/9376	8.78725398313027	PLCB4/PRKCG	3.7386767321794
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	2/22	98/9376	8.69758812615955	PLCB4/PRKCG	3.71482893149195
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	2/22	98/9376	8.69758812615955	PLCB4/PRKCG	3.71482893149195
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	2/22	99/9376	8.60973370064279	PLCB4/PRKCG	3.69131896440195
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	2/22	101/9376	8.43924392439244	PLCB4/PRKCG	3.64527941013998
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	2/22	102/9376	8.35650623885918	PLCB4/PRKCG	3.62273397084468
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/22	103/9376	8.27537511032657	PLCB4/PRKCG	3.6004946361544
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/22	110/9376	7.74876033057851	PRKCG/EGLN2	3.45280852867001
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/22	115/9376	7.41185770750988	PLCB4/PRKCG	3.35507435781352
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/22	115/9376	7.41185770750988	PLCB4/PRKCG	3.35507435781352
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/22	115/9376	7.41185770750988	PLCB4/PRKCG	3.35507435781352
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	2/22	116/9376	7.34796238244514	PLCB4/PRKCG	3.33623121599058
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/22	122/9376	6.9865871833085	PLCB4/PRKCG	3.22769712312151
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/22	122/9376	6.9865871833085	PLCB4/PRKCG	3.22769712312151
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/22	125/9376	6.81890909090909	PLCB4/PRKCG	3.17614655858529
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/22	133/9376	6.40874914559125	PLCB4/PRKCG	3.04659327708325
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/22	134/9376	6.36092265943012	PLCB4/PRKCG	3.03114878744685
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/22	144/9376	5.91919191919192	PLCB4/PRKCG	2.88486444095141
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/22	149/9376	5.72056131787675	PLCB4/PRKCG	2.81679222306795
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/22	154/9376	5.53482880755608	PLCB4/PRKCG	2.75173744806278
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/22	155/9376	5.49912023460411	PDE11A/PLCB4	2.73906749008274
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	2/22	156/9376	5.46386946386946	IFIT1/OAS2	2.72650702240357
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	2/22	178/9376	4.78855975485189	PLCB4/PRKCG	2.4747750896202
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/22	187/9376	4.55809431210501	OAS2/PLCB4	2.3834301499769
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/22	195/9376	4.37109557109557	PLCB4/PRKCG	2.30696854377758
NA	NA	hsa04082	Neuroactive ligand signaling	2/22	199/9376	4.28323435358611	PLCB4/PRKCG	2.2702639422521
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	2/22	205/9376	4.15787139689579	PLCB4/PRKCG	2.21697767194379
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/22	38/9376	11.2153110047847	PRKCG	3.0599529766893
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/22	214/9376	3.98300764655905	APOBEC3B/PRKCG	2.14074237300755
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	2/22	227/9376	3.75490588706448	PLCB4/PRKCG	2.03765745485342
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	1/22	44/9376	9.68595041322314	GTF2H2	2.80062276528686
Genetic Information Processing	Replication and repair	hsa03410	Base excision repair	1/22	44/9376	9.68595041322314	NEIL3	2.80062276528686
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/22	45/9376	9.47070707070707	ABCA3	2.76223180460712
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	2/22	238/9376	3.58135981665393	FGFR4/PRKCG	1.95618418156528
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	2/22	238/9376	3.58135981665393	OAS2/PRKCG	1.95618418156528
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/22	48/9376	8.87878787878788	PLCB4	2.65389694121851
Genetic Information Processing	Replication and repair	hsa03460	Fanconi anemia pathway	1/22	54/9376	7.89225589225589	CENPS-CORT	2.46321329393065
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/22	56/9376	7.61038961038961	EVC2	2.40608746360585
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/22	60/9376	7.1030303030303	PRKCG	2.29987751549045
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/22	63/9376	6.76479076479076	GTF2H2	2.22642114571605
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/22	65/9376	6.55664335664336	PLCB4	2.1800644554404
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/22	69/9376	6.17654808959157	PLCB4	2.09294703073387
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/22	69/9376	6.17654808959157	PRKCG	2.09294703073387
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/22	70/9376	6.08831168831169	EGLN2	2.0722373550555
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/22	300/9376	2.84121212121212	FGFR4/PRKCG	1.57186594490833
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/22	73/9376	5.83810709838107	PRKCG	2.01244348615062
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	2/22	308/9376	2.76741440377804	PLCB4/TGM2	1.52952397324567
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/22	76/9376	5.60765550239234	PRKCG	1.9558863631216
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/22	78/9376	5.46386946386946	PLCB4	1.91982796000668
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/22	80/9376	5.32727272727273	PRKCG	1.88499194783569
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/22	86/9376	4.95560253699789	PRKCG	1.78711422294197
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/22	86/9376	4.95560253699789	PLCB4	1.78711422294197
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/22	89/9376	4.78855975485189	PRKCG	1.74152501868848
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/22	93/9376	4.58260019550342	PLCB4	1.68381331769818
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/22	98/9376	4.34879406307978	PRKCG	1.61611622592022
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/22	99/9376	4.3048668503214	PRKCG	1.60312018256095
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/22	100/9376	4.26181818181818	TNFRSF10D	1.59029493247637
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/22	101/9376	4.21962196219622	PLCB4	1.57763635209567
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/22	103/9376	4.13768755516328	PLCB4	1.55280340064648
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/22	107/9376	3.98300764655905	PLCB4	1.50497092662445
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/22	116/9376	3.67398119122257	PRKCG	1.4053359146864
Organismal Systems	Immune system	hsa04611	Platelet activation	1/22	126/9376	3.38239538239538	PLCB4	1.30564930127537
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/22	128/9376	3.32954545454545	PDE11A	1.28691706260802
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/22	130/9376	3.27832167832168	PLCB4	1.26855140289414
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/22	133/9376	3.20437457279563	PRKCG	1.24166097795949
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/22	136/9376	3.13368983957219	OAS2	1.21552264347713
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/22	138/9376	3.08827404479578	REC8	1.19849534271274
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/22	139/9376	3.06605624591236	PLCB4	1.19009701153335
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/22	140/9376	3.04415584415584	PLCB4	1.18177379177577
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/22	144/9376	2.95959595959596	FGFR4	1.14920677935231
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/22	149/9376	2.86028065893838	PLCB4	1.11004258603259
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/22	154/9376	2.76741440377804	PLCB4	1.07246835713356
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/22	157/9376	2.71453387376954	ZFP36L1	1.05063601586568
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	2/22	480/9376	1.77575757575758	PLCB4/PRKCG	0.846150378067023
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/22	158/9376	2.69735327963176	PRKCG	1.04347183506522
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/22	163/9376	2.61461238148355	PRKCG	1.00846270312673
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/22	166/9376	2.56736035049288	PLCB4	0.988078344298461
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/22	168/9376	2.53679653679654	PPIAL4G	0.974735210746449
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/22	170/9376	2.50695187165775	YBX3	0.961582727033644
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/22	170/9376	2.50695187165775	PRKCG	0.961582727033644
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/22	173/9376	2.46347871781398	OAS2	0.942199886527507
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/22	180/9376	2.36767676767677	OAS2	0.898500942132755
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/22	193/9376	2.20819594912859	PLCB4	0.822473726352532
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/22	194/9376	2.19681349578257	KIF18B	0.816877613527996
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/22	201/9376	2.12030755314337	ETV1	0.778628958978274
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	1/22	203/9376	2.09941782355575	PRKCG	0.767986156114184
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	1/22	204/9376	2.0891265597148	PRKCG	0.76271046534514
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/22	205/9376	2.07893569844789	OAS2	0.757464776834608
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	1/22	205/9376	2.07893569844789	GTF2H2	0.757464776834608
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/22	216/9376	1.97306397306397	PLCB4	0.701647250981569
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/22	217/9376	1.96397151235861	PRKCG	0.696736131566795
NA	NA	hsa04081	Hormone signaling	1/22	219/9376	1.94603569946036	PLCB4	0.686991353953673
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	1/22	232/9376	1.83699059561129	FGFR4	0.626029441189861
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/22	250/9376	1.70472727272727	FGFR4	0.547708078703346
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/22	253/9376	1.68451311534315	PLCB4	0.535268261271876
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/22	298/9376	1.43014032946919	TNFRSF10D	0.365949789836214
NA	NA	hsa04517	IgSF CAM signaling	1/22	299/9376	1.42535725144421	PRKCG	0.362507138620174
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/22	323/9376	1.31944835350408	PRKCG	0.283337430331651
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	1/22	362/9376	1.17729784028127	FGFR4	0.166838873794699
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/22	370/9376	1.15184275184275	GLP2R	0.144519766899208
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	1/22	388/9376	1.09840674789128	PLCB4	0.0960080184933835