category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	13/102	238/9376	5.02092601746581	RPS10/RPS21/RPS29/RPL36A/RPS27/RPL17/RPL26/RPL39/RPL41/ADAM17/RPL34/RPL37/RPL38	6.58932854980159
Genetic Information Processing	Translation	hsa03010	Ribosome	12/102	222/9376	4.96873343932167	RPS10/RPS21/RPS29/RPL36A/RPS27/RPL17/RPL26/RPL39/RPL41/RPL34/RPL37/RPL38	6.27588738399642
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	4/102	44/9376	8.35650623885918	GTF2H2/CCNH/GTF2A1/GTF2H2C	5.12935502010898
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	4/102	63/9376	5.83629007158419	GTF2H2/ERCC5/CCNH/GTF2H2C	4.03915010257199
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	3/102	56/9376	4.92436974789916	MGAT4C/MAGT1/ALG10B	3.08893062719662
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	5/102	157/9376	2.9274384913201	SMAD7/WNT2B/BBC3/CCND3/PPP1CB	2.55411604127244
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	2/102	27/9376	6.80900508351489	ACOX1/ELOVL5	3.16995602122519
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	4/102	116/9376	3.16970926301555	PGAM2/HK2/PRPS2/ACOX1	2.4659100049123
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/102	78/9376	3.53544494720965	ARHGEF26/ACTR3C/DNM2	2.35808194879246
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	3/102	83/9376	3.32246633593196	EZH2/E2F6/ASXL1	2.22875681186419
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/102	39/9376	4.71392659627954	HLA-DQA2/CD80	2.43732878917239
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/102	42/9376	4.37721755368814	TFRC/PRNP	2.30039260680102
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	2/102	44/9376	4.17825311942959	MGAT4C/MAGT1	2.21605040001316
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/102	44/9376	4.17825311942959	HLA-DQA2/CD80	2.21605040001316
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	2/102	45/9376	4.08540305010893	ABCG8/ABCC1	2.17573623695295
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	2/102	45/9376	4.08540305010893	HLA-DQA2/CD80	2.17573623695295
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	2/102	46/9376	3.99658994032396	PSMA2/PSMD11	2.13657227986995
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	4/102	157/9376	2.34195079305608	DUSP8/ADAM17/NFATC1/S1PR1	1.77826585002737
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/102	50/9376	3.67686274509804	HLA-DQA2/CD80	1.99028641383428
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	3/102	105/9376	2.62633053221289	USP30/ARIH1/GABARAP	1.7574879365073
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	3/102	109/9376	2.52995143011333	HLA-DQA2/IL27RA/NFATC1	1.68489751464165
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/102	54/9376	3.40450254175744	HLA-DQA2/CD80	1.85831678409767
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	3/102	110/9376	2.50695187165775	SMAD7/TFRC/SKIL	1.66725395067587
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	4/102	174/9376	2.11313950867703	FBXO2/ERO1A/MAGT1/EDEM1	1.55430156905156
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	2/102	57/9376	3.22531819745442	ACOX1/ELOVL5	1.76724625348057
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	4/102	178/9376	2.06565322758317	WNT2B/CCND3/NFATC1/RYK	1.50532883755526
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	2/102	66/9376	2.78550207961973	HLA-DQA2/NFATC1	1.52654519277642
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	2/102	67/9376	2.74392742171495	PGAM2/HK2	1.50233391370624
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	1/102	17/9376	5.40715109573241	TFRC	1.90730371885971
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/102	70/9376	2.62633053221289	HLA-DQA2/CD80	1.43228185346883
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	5/102	275/9376	1.67130124777184	PSMA2/CACNA1F/PSMD11/PRNP/TUBB4B	1.18492652782647
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	2/102	71/9376	2.58933996133665	PGAM2/HK2	1.40974306581405
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	4/102	204/9376	1.80238369857747	WNT2B/DDX5/PPP1CB/EZR	1.21511487074613
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	4/102	205/9376	1.79359158297465	GTF2H2/CCND3/GTF2A1/GTF2H2C	1.20480792353004
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	2/102	73/9376	2.51839914047811	APOBEC3H/ELL2	1.36580295222548
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	2/102	75/9376	2.45124183006536	PGAM2/PRPS2	1.32329836422399
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/102	75/9376	2.45124183006536	BBC3/CCND3	1.32329836422399
Metabolism	Lipid metabolism	hsa00100	Steroid biosynthesis	1/102	20/9376	4.59607843137255	CYP51A1	1.68830623677359
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	4/102	212/9376	1.73436921938587	FARP2/F2RL3/SIPA1L1/PRKD3	1.13420624422157
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/102	142/9376	1.94200497100249	JUND/CYLD/NFATC1	1.1861909601032
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	2/102	78/9376	2.35696329813977	PI4K2B/IMPA1	1.26203909970074
Metabolism	Metabolism of terpenoids and polyketides	hsa00900	Terpenoid backbone biosynthesis	1/102	23/9376	3.99658994032396	IDI1	1.5089260157529
Metabolism	Glycan biosynthesis and metabolism	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	1/102	24/9376	3.83006535947712	NDST2	1.45580100754758
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	4/102	226/9376	1.62693041818497	CACNA1F/ACOX1/NFATC1/PPP1CB	1.00049562257837
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/102	154/9376	1.79067990832697	CACNA1F/NFATC1/PPP1CB	1.03753004755154
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	3/102	155/9376	1.77912713472486	HLA-DQA2/TFRC/TUBB4B	1.02574012872094
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/102	157/9376	1.75646309479206	CCND3/NFATC1/PPP1CB	1.0024156587823
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	5/102	308/9376	1.49223325693914	PSMA2/BBC3/IFT57/PSMD11/TUBB4B	0.921176252621968
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	6/102	388/9376	1.4214675560946	PSMA2/CACNA1F/ADAM17/WNT2B/PSMD11/TUBB4B	0.889202465436732
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	1/102	26/9376	3.53544494720965	ACOX1	1.35764814914242
Organismal Systems	Digestive system	hsa04977	Vitamin digestion and absorption	1/102	26/9376	3.53544494720965	ABCC1	1.35764814914242
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/102	89/9376	2.06565322758317	CACNA1F/GABARAP	1.0593155891019
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/102	28/9376	3.28291316526611	ELOVL5	1.26870670400711
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	7/102	480/9376	1.34052287581699	PSMA2/CACNA1F/WNT2B/IFT57/PSMD11/PRNP/TUBB4B	0.803196305853211
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/102	93/9376	1.97680792747206	HLA-DQA2/NFATC1	0.992792877770882
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/102	166/9376	1.66123316796598	CACNA1F/NFATC1/PPP1CB	0.901427986073548
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/102	94/9376	1.95577805590321	JUND/MAPK6	0.97668018820086
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/102	95/9376	1.93519091847265	HLA-DQA2/CD80	0.960764340230554
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/102	30/9376	3.0640522875817	ABCC1	1.18746443762579
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	4/102	248/9376	1.48260594560405	ARHGEF26/ACTR3C/DNM2/TUBB4B	0.807760981637665
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/102	31/9376	2.9652118912081	PRPS2	1.14935120552944
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	1/102	31/9376	2.9652118912081	ACOX1	1.14935120552944
NA	NA	hsa04981	Folate transport and metabolism	1/102	31/9376	2.9652118912081	ABCC1	1.14935120552944
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	2/102	98/9376	1.87595038015206	PI4K2B/IMPA1	0.914150155552429
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/102	98/9376	1.87595038015206	ACTR3C/DNM2	0.914150155552429
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	2/102	98/9376	1.87595038015206	CACNA1F/PRKD3	0.914150155552429
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	4/102	250/9376	1.47074509803922	TFRC/ACTR3C/VPS26A/DNM2	0.791166257511609
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/102	32/9376	2.87254901960784	HK2	1.11274063546937
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/102	32/9376	2.87254901960784	ACOX1	1.11274063546937
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/102	32/9376	2.87254901960784	GABARAP	1.11274063546937
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/102	32/9376	2.87254901960784	BBC3	1.11274063546937
Human Diseases	Immune disease	hsa05310	Asthma	1/102	32/9376	2.87254901960784	HLA-DQA2	1.11274063546937
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/102	100/9376	1.83843137254902	HLA-DQA2/TFRC	0.883973668833634
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/102	101/9376	1.8202290817317	COL4A4/NFATC1	0.869142665194856
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/102	33/9376	2.78550207961973	STX5	1.07752246686912
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/102	103/9376	1.78488482771749	COL4A4/SERPINB9	0.839975453205119
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/102	34/9376	2.70357554786621	RORB	1.04359767573131
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/102	180/9376	1.53202614379085	HLA-DQA2/SRSF3/PPP1CB	0.755826167588346
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/102	105/9376	1.75088702147526	CYLD/NFATC1	0.811443218819136
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/102	35/9376	2.62633053221289	HK2	1.01087703365112
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/102	36/9376	2.55337690631808	HK2	0.979279887158532
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	2/102	108/9376	1.70225127087872	XPO4/NUP58	0.769774601044184
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	1/102	37/9376	2.48436671966084	HK2	0.948733118583049
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/102	110/9376	1.67130124777184	HK2/TFRC	0.742710950821544
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/102	38/9376	2.41898864809082	HK2	0.919170257321039
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/102	115/9376	1.59863597612958	JUND/WNK3	0.677384054775284
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/102	41/9376	2.24198947871832	PGAM2	0.835804802647989
Genetic Information Processing	Replication and repair	hsa03440	Homologous recombination	1/102	41/9376	2.24198947871832	SYCP3	0.835804802647989
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/102	200/9376	1.37882352941176	ACTR3C/TUBB4B/EZR	0.567907258724951
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	5/102	368/9376	1.24893435635124	PSMA2/SRSF3/PSMD11/NUP58/TUBB4B	0.510912746981519
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/102	119/9376	1.5449003130664	ADAM17/CYLD	0.627346651923705
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/102	43/9376	2.13771089831281	ACOX1	0.784165428161155
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/102	43/9376	2.13771089831281	ABCG8	0.784165428161155
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/102	203/9376	1.35844682700666	COL4A4/CCND3/PPP1CB	0.541463568124081
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	3/102	205/9376	1.34519368723099	HLA-DQA2/CCND3/PSMD11	0.524063130772556
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/102	125/9376	1.47074509803922	ABCC1/S1PR1	0.555646586438861
Organismal Systems	Immune system	hsa04611	Platelet activation	2/102	126/9376	1.45907251789605	F2RL3/PPP1CB	0.544061355558081
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/102	47/9376	1.95577805590321	HK2	0.688875304316203
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/102	128/9376	1.43627450980392	PRPS2/ADK	0.521186420680347
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/102	48/9376	1.91503267973856	HK2	0.666522988864428
NA	NA	hsa04517	IgSF CAM signaling	4/102	299/9376	1.22971998163814	CD80/ACTR3C/TUBB4B/EZR	0.423365415298349
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	4/102	300/9376	1.22562091503268	JUND/CACNA1F/DUSP8/NFATC1	0.41652868790942
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/102	50/9376	1.83843137254902	AMD1	0.623385929208569
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	2/102	133/9376	1.38227922748047	S1PR1/GABARAP	0.46564208153601
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/102	51/9376	1.80238369857747	TMEM86B	0.602552569778301
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/102	51/9376	1.80238369857747	ERO1A	0.602552569778301
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/102	134/9376	1.37196371085748	CACNA1F/PPP1CB	0.454801791927358
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/102	52/9376	1.76772247360483	ABCG8	0.582179584253861
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/102	136/9376	1.3517877739331	BBC3/CCND3	0.433377528724378
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/102	53/9376	1.73436921938587	DNM2	0.562246468631856
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/102	137/9376	1.3419207098898	BBC3/CTSH	0.422790660207561
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	3/102	224/9376	1.23109243697479	HLA-DQA2/CCND3/NFATC1	0.367116508397032
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	2/102	138/9376	1.33219664677465	STAG3/PPP1CB	0.412285429612085
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	2/102	138/9376	1.33219664677465	HK2/PPP1CB	0.412285429612085
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/102	138/9376	1.33219664677465	NFATC1/ACTR3C	0.412285429612085
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/102	54/9376	1.70225127087872	AMD1	0.542734016980503
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/102	56/9376	1.64145658263305	EEF1G	0.50490015248253
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/102	143/9376	1.28561634443987	HLA-DQA2/CD80	0.360937358490165
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	3/102	232/9376	1.18864097363083	PPP1CB/ACTR3C/EZR	0.305115374086998
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/102	144/9376	1.27668845315904	WNT2B/SKIL	0.350894500664889
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/102	144/9376	1.27668845315904	PSMA2/PSMD11	0.350894500664889
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/102	62/9376	1.48260594560405	ADAM17	0.399827419755143
Genetic Information Processing	Transcription	hsa03040	Spliceosome	3/102	243/9376	1.13483418058581	DDX5/SRSF3/BCAS2	0.223330781922231
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/102	63/9376	1.45907251789605	EZH2	0.383406036507734
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/102	63/9376	1.45907251789605	WNT2B	0.383406036507734
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	2/102	154/9376	1.19378660555131	CACNA1F/PPP1CB	0.254286752395079
NA	NA	hsa04518	Integrin signaling	2/102	154/9376	1.19378660555131	COL4A4/CCND3	0.254286752395079
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/102	155/9376	1.18608475648324	CACNA1F/WNT2B	0.244985180930102
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/102	65/9376	1.41417797888386	GPAT4	0.351396715467757
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/102	65/9376	1.41417797888386	CACNA1F	0.351396715467757
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/102	65/9376	1.41417797888386	CACNA1F	0.351396715467757
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	2/102	158/9376	1.16356415984115	CCNH/CCND3	0.217445546388803
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/102	67/9376	1.37196371085748	PPP1CB	0.320434033280857
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/102	160/9376	1.14901960784314	HLA-DQA2/CD80	0.199381267600332
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/102	69/9376	1.33219664677465	CACNA1F	0.290447144450677
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/102	69/9376	1.33219664677465	PPP1CB	0.290447144450677
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/102	71/9376	1.29466998066832	ADAM17	0.261371998474993
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/102	72/9376	1.27668845315904	CYLD	0.24715796518506
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/102	168/9376	1.09430438842204	IL27RA/CCND3	0.129346912559723
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/102	169/9376	1.08782921452605	WDR45B/GABARAP	0.120830189840551
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	2/102	170/9376	1.08143021914648	ACTR3C/EZR	0.112363887766745
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/102	75/9376	1.22562091503268	BBC3	0.205729866388993
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	3/102	268/9376	1.02897278314311	PSMA2/PSMD11/TUBB4B	0.0504659299049161
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/102	173/9376	1.06267709395897	HLA-DQA2/CCND3	0.0872608363040311
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/102	76/9376	1.20949432404541	ACOX1	0.192304639042822
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/102	76/9376	1.20949432404541	EZR	0.192304639042822
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/102	78/9376	1.17848164906988	CNOT9	0.165996250609027
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/102	78/9376	1.17848164906988	HLA-DQA2	0.165996250609027
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/102	79/9376	1.16356415984115	DNM2	0.153102561112053
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/102	82/9376	1.12099473935916	HLA-DQA2	0.115404902596457
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/102	83/9376	1.10748877864399	ACOX1	0.103151698646954
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/102	85/9376	1.08143021914648	ADK	0.0790889873127914
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/102	86/9376	1.06885544915641	CACNA1F	0.0672716163258124
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/102	86/9376	1.06885544915641	CACNA1F	0.0672716163258124
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	1/102	87/9376	1.05656975433852	CACNA1F	0.0555919126062345
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/102	87/9376	1.05656975433852	BBC3	0.0555919126062345
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/102	88/9376	1.0445632798574	F2RL3	0.0440463127764659
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/102	89/9376	1.03282661379158	COL4A4	0.0326313877974329
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/102	89/9376	1.03282661379158	TUBB4B	0.0326313877974329
Cellular Processes	Cell motility	hsa04814	Motor proteins	2/102	194/9376	0.947645037396402	KIF18B/TUBB4B	-0.0772755763305827
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/102	90/9376	1.02135076252723	ABCG8	0.0213438364058217
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/102	90/9376	1.02135076252723	NFATC1	0.0213438364058217
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/102	91/9376	1.01012712777419	NFATC1	0.0101804789423905
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/102	93/9376	0.988403963736032	FARP2	-0.0117857993260087
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/102	93/9376	0.988403963736032	CACNA1F	-0.0117857993260087
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/102	93/9376	0.988403963736032	COL4A4	-0.0117857993260087
NA	NA	hsa04519	Cadherin signaling	4/102	404/9376	0.910114540865851	WNT2B/RYK/PPP1CB/ACTR3C	-0.193681290226713
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/102	201/9376	0.914642473904985	DDX5/SS18	-0.128288873034901
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/102	99/9376	0.928500693206576	PPP1CB	-0.0750011337645336
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/102	99/9376	0.928500693206576	HLA-DQA2	-0.0750011337645336
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/102	99/9376	0.928500693206576	CACNA1F	-0.0750011337645336
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/102	101/9376	0.910114540865851	WNT2B	-0.0952456932509393
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/102	103/9376	0.892442413858747	PPP1CB	-0.115106992738514
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/102	103/9376	0.892442413858747	COL4A4	-0.115106992738514
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/102	214/9376	0.859080080630383	APOBEC3H/NFATC1	-0.218693717602969
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/102	104/9376	0.883861236802413	GPAT4	-0.124899106988808
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/102	105/9376	0.875443510737628	CYLD	-0.134601498869028
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/102	105/9376	0.875443510737628	CACNA1F	-0.134601498869028
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/102	216/9376	0.851125635439361	ERO1A/NFATC1	-0.232140672288894
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	2/102	217/9376	0.847203397488028	CACNA1F/CCND3	-0.238820560550643
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	3/102	323/9376	0.85376069932617	EZH2/ABCC1/EZR	-0.280492517803421
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/102	107/9376	0.859080080630383	PGAM2	-0.15374464997649
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/102	109/9376	0.84331714337111	CD80	-0.172550938889228
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/102	109/9376	0.84331714337111	PPP1CB	-0.172550938889228
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/102	333/9376	0.828122239886946	COL4A4/WNT2B/CCND3	-0.334917403040714
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/102	112/9376	0.820728291316527	HLA-DQA2	-0.200158332508106
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/102	115/9376	0.799317988064791	CACNA1F	-0.227080897883939
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/102	115/9376	0.799317988064791	CACNA1F	-0.227080897883939
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/102	116/9376	0.792427315753888	EZR	-0.235909744938634
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/102	117/9376	0.785654432713256	SS18	-0.244668226385693
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/102	122/9376	0.753455480552877	NFATC1	-0.287450255428572
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/102	122/9376	0.753455480552877	CACNA1F	-0.287450255428572
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/102	250/9376	0.735372549019608	CTSH/VPS26A	-0.444750908504527
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/102	130/9376	0.707088989441931	COL4A4	-0.352681441396977
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/102	253/9376	0.726652716422537	HK2/ACTR3C	-0.4622302499937
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/102	254/9376	0.723791878956307	CACNA1F/NFATC1	-0.468015725929763
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/102	133/9376	0.691139613740233	NFATC1	-0.376212942853044
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/102	133/9376	0.691139613740233	PPP1CB	-0.376212942853044
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	3/102	370/9376	0.745310015898251	CHRNA5/F2RL3/S1PR1	-0.524202315921116
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	1/102	138/9376	0.666098323387326	LHPP	-0.4144015224929
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/102	142/9376	0.647334990334162	FBXO2	-0.444082631501548
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/102	144/9376	0.638344226579521	ACOX1	-0.458649504806076
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/102	148/9376	0.621091679915209	WNT2B	-0.487262943841927
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/102	149/9376	0.616923279378866	DNM2	-0.494311612486197
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/102	149/9376	0.616923279378866	CACNA1F	-0.494311612486197
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/102	150/9376	0.61281045751634	WNT2B	-0.501319619909829
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/102	158/9376	0.581782079920576	WNT2B	-0.555987474453919
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/102	163/9376	0.563936003849393	NFATC1	-0.588973392244996
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/102	168/9376	0.547152194211018	CYLD	-0.62112131278679
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/102	170/9376	0.540715109573241	WNT2B	-0.633757791908184
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/102	181/9376	0.507853970317409	HLA-DQA2	-0.701147814713894
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	1/102	183/9376	0.502303653701918	GNL3L	-0.713039428795606
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/102	184/9376	0.499573742540494	RYK	-0.718945833343779
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/102	187/9376	0.491559190521128	GABARAP	-0.736511033492282
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/102	191/9376	0.481264757211785	PPP1CB	-0.759582650439942
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/102	196/9376	0.468987595038015	NFATC1	-0.787886284057949
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	1/102	205/9376	0.448397895743663	PPP1CB	-0.837426454742402
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	2/102	362/9376	0.507853970317409	COL4A4/CCND3	-1.00147859769181
NA	NA	hsa04382	Cornified envelope formation	1/102	217/9376	0.423601698744014	COL4A4	-0.900908548641368
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/102	227/9376	0.404940830957934	NFATC1	-0.951784098095447
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/102	227/9376	0.404940830957934	PRKD3	-0.951784098095447
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	1/102	233/9376	0.394513170074897	COL4A4	-0.981500398080225
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	1/102	235/9376	0.391155611180642	COX16	-0.991278217087322
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/102	298/9376	0.308461639689433	IL27RA	-1.27227647514237