ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 12/221 175/18639 0.0685714285714286 5.78327084680026 1.2298316007052e-06 0.000602724428839556 GO:0034987 immunoglobulin receptor binding 5/221 19/18639 0.263157894736842 22.1945701357466 2.27443180694172e-06 0.000602724428839556 GO:0140693 molecular condensate scaffold activity 4/221 48/18639 0.0833333333333333 7.02828054298643 0.00248772660975495 0.439498367723375 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/221 15/18639 0.133333333333333 11.2452488687783 0.0132749957465447 0.625324033800962 GO:0005521 lamin binding 2/221 16/18639 0.125 10.5424208144796 0.0150540515014915 0.625324033800962 GO:0046624 sphingolipid transporter activity 2/221 19/18639 0.105263157894737 8.87782805429864 0.0209589441064908 0.625324033800962 GO:0015095 magnesium ion transmembrane transporter activity 2/221 20/18639 0.1 8.43393665158371 0.0231082615377995 0.625324033800962 GO:0016251 RNA polymerase II general transcription initiation factor activity 3/221 53/18639 0.0566037735849057 4.77392640655682 0.0249506228939351 0.625324033800962 GO:0016860 intramolecular oxidoreductase activity 3/221 53/18639 0.0566037735849057 4.77392640655682 0.0249506228939351 0.625324033800962 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/221 21/18639 0.0952380952380952 8.03232062055591 0.0253440897232739 0.625324033800962 GO:0140517 protein-RNA adaptor activity 2/221 22/18639 0.0909090909090909 7.66721513780337 0.0276640947143454 0.625324033800962 GO:0048027 mRNA 5'-UTR binding 2/221 24/18639 0.0833333333333333 7.02828054298643 0.0325475123604471 0.625324033800962 GO:0016866 intramolecular transferase activity 2/221 28/18639 0.0714285714285714 6.02424046541694 0.0432264375988632 0.625324033800962 GO:0046625 sphingolipid binding 2/221 28/18639 0.0714285714285714 6.02424046541694 0.0432264375988632 0.625324033800962 GO:0140223 general transcription initiation factor activity 3/221 68/18639 0.0441176470588235 3.72085440511046 0.0469755118357505 0.625324033800962 GO:1990841 promoter-specific chromatin binding 3/221 68/18639 0.0441176470588235 3.72085440511046 0.0469755118357505 0.625324033800962 GO:0031624 ubiquitin conjugating enzyme binding 2/221 30/18639 0.0666666666666667 5.62262443438914 0.0489882226448791 0.625324033800962 GO:0048019 receptor antagonist activity 2/221 30/18639 0.0666666666666667 5.62262443438914 0.0489882226448791 0.625324033800962 GO:0072349 modified amino acid transmembrane transporter activity 2/221 31/18639 0.0645161290322581 5.44124945263465 0.0519676247584058 0.625324033800962 GO:0003823 antigen binding 5/221 174/18639 0.028735632183908 2.42354501482291 0.0565492464774005 0.625324033800962 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 4/221 122/18639 0.0327868852459016 2.76522513166679 0.0574062831340364 0.625324033800962 GO:0003725 double-stranded RNA binding 3/221 75/18639 0.04 3.37357466063348 0.05965550240235 0.625324033800962 GO:0015035 protein-disulfide reductase activity 2/221 34/18639 0.0588235294117647 4.96113920681395 0.0612767466660352 0.625324033800962 GO:0016853 isomerase activity 5/221 180/18639 0.0277777777777778 2.34276018099548 0.0635123620971836 0.625324033800962 GO:0046332 SMAD binding 3/221 79/18639 0.0379746835443038 3.20276075376597 0.0675476077526167 0.625324033800962 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/221 36/18639 0.0555555555555556 4.68552036199095 0.0677733738942489 0.625324033800962 GO:0005109 frizzled binding 2/221 38/18639 0.0526315789473684 4.43891402714932 0.0744857735716521 0.625324033800962 GO:0008135 translation factor activity, RNA binding 3/221 83/18639 0.036144578313253 3.04841083792182 0.0758886749675775 0.625324033800962 GO:0030165 PDZ domain binding 3/221 83/18639 0.036144578313253 3.04841083792182 0.0758886749675775 0.625324033800962 GO:0000217 DNA secondary structure binding 2/221 39/18639 0.0512820512820513 4.32509571876088 0.0779185933359345 0.625324033800962 GO:0180051 translation factor activity 3/221 84/18639 0.0357142857142857 3.01212023270847 0.0780419421327059 0.625324033800962 GO:0015036 disulfide oxidoreductase activity 2/221 40/18639 0.05 4.21696832579186 0.0814002681285258 0.625324033800962 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/221 40/18639 0.05 4.21696832579186 0.0814002681285258 0.625324033800962 GO:0061791 GTPase motor activity 2/221 40/18639 0.05 4.21696832579186 0.0814002681285258 0.625324033800962 GO:0071949 FAD binding 2/221 40/18639 0.05 4.21696832579186 0.0814002681285258 0.625324033800962 GO:1990606 membrane scission GTPase motor activity 2/221 40/18639 0.05 4.21696832579186 0.0814002681285258 0.625324033800962 GO:0140767 enzyme-substrate adaptor activity 4/221 139/18639 0.0287769784172662 2.42703212995215 0.0836908713726564 0.625324033800962 GO:0004197 cysteine-type endopeptidase activity 3/221 88/18639 0.0340909090909091 2.87520567667626 0.0869179665705865 0.625324033800962 GO:0019894 kinesin binding 2/221 42/18639 0.0476190476190476 4.01616031027796 0.088503699775316 0.625324033800962 GO:0001046 core promoter sequence-specific DNA binding 2/221 44/18639 0.0454545454545455 3.83360756890169 0.0957834137799072 0.625324033800962 GO:0030547 signaling receptor inhibitor activity 2/221 44/18639 0.0454545454545455 3.83360756890169 0.0957834137799072 0.625324033800962 GO:0045296 cadherin binding 7/221 334/18639 0.0209580838323353 1.76759151380497 0.10343067436237 0.625324033800962 GO:0016791 phosphatase activity 6/221 273/18639 0.021978021978022 1.85361245089752 0.106911093146865 0.625324033800962 GO:0140359 ABC-type transporter activity 2/221 47/18639 0.0425531914893617 3.58890921343988 0.107007026150749 0.625324033800962 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/221 48/18639 0.0416666666666667 3.51414027149321 0.110823488328551 0.625324033800962 GO:0005528 FK506 binding 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0008190 eukaryotic initiation factor 4E binding 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0008519 ammonium channel activity 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0016868 intramolecular phosphotransferase activity 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0032395 MHC class II receptor activity 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0033204 ribonuclease P RNA binding 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0035256 G protein-coupled glutamate receptor binding 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0042975 peroxisome proliferator activated receptor binding 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0045322 unmethylated CpG binding 1/221 10/18639 0.1 8.43393665158371 0.112463919012624 0.625324033800962 GO:0003743 translation initiation factor activity 2/221 51/18639 0.0392156862745098 3.30742613787596 0.122479171751256 0.625324033800962 GO:0030544 Hsp70 protein binding 2/221 51/18639 0.0392156862745098 3.30742613787596 0.122479171751256 0.625324033800962 GO:0005536 D-glucose binding 1/221 11/18639 0.0909090909090909 7.66721513780337 0.122992958354414 0.625324033800962 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/221 11/18639 0.0909090909090909 7.66721513780337 0.122992958354414 0.625324033800962 GO:0019206 nucleoside kinase activity 1/221 11/18639 0.0909090909090909 7.66721513780337 0.122992958354414 0.625324033800962 GO:0019215 intermediate filament binding 1/221 11/18639 0.0909090909090909 7.66721513780337 0.122992958354414 0.625324033800962 GO:0034713 type I transforming growth factor beta receptor binding 1/221 11/18639 0.0909090909090909 7.66721513780337 0.122992958354414 0.625324033800962 GO:0070697 activin receptor binding 1/221 11/18639 0.0909090909090909 7.66721513780337 0.122992958354414 0.625324033800962 GO:1990948 ubiquitin ligase inhibitor activity 1/221 11/18639 0.0909090909090909 7.66721513780337 0.122992958354414 0.625324033800962 GO:0004126 cytidine deaminase activity 1/221 12/18639 0.0833333333333333 7.02828054298643 0.133397647865025 0.625324033800962 GO:0004526 ribonuclease P activity 1/221 12/18639 0.0833333333333333 7.02828054298643 0.133397647865025 0.625324033800962 GO:0005049 nuclear export signal receptor activity 1/221 12/18639 0.0833333333333333 7.02828054298643 0.133397647865025 0.625324033800962 GO:0005095 GTPase inhibitor activity 1/221 12/18639 0.0833333333333333 7.02828054298643 0.133397647865025 0.625324033800962 GO:0005527 macrolide binding 1/221 12/18639 0.0833333333333333 7.02828054298643 0.133397647865025 0.625324033800962 GO:0016801 hydrolase activity, acting on ether bonds 1/221 12/18639 0.0833333333333333 7.02828054298643 0.133397647865025 0.625324033800962 GO:0016803 ether hydrolase activity 1/221 12/18639 0.0833333333333333 7.02828054298643 0.133397647865025 0.625324033800962 GO:0017166 vinculin binding 1/221 12/18639 0.0833333333333333 7.02828054298643 0.133397647865025 0.625324033800962 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/221 12/18639 0.0833333333333333 7.02828054298643 0.133397647865025 0.625324033800962 GO:0035197 siRNA binding 1/221 12/18639 0.0833333333333333 7.02828054298643 0.133397647865025 0.625324033800962 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/221 12/18639 0.0833333333333333 7.02828054298643 0.133397647865025 0.625324033800962 GO:0097371 MDM2/MDM4 family protein binding 1/221 12/18639 0.0833333333333333 7.02828054298643 0.133397647865025 0.625324033800962 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/221 54/18639 0.037037037037037 3.1236802413273 0.134416512585396 0.625324033800962 GO:0140463 chromatin-protein adaptor activity 2/221 54/18639 0.037037037037037 3.1236802413273 0.134416512585396 0.625324033800962 GO:0003712 transcription coregulator activity 9/221 495/18639 0.0181818181818182 1.53344302756067 0.135436355311552 0.625324033800962 GO:0004843 cysteine-type deubiquitinase activity 3/221 108/18639 0.0277777777777778 2.34276018099548 0.136960189454006 0.625324033800962 GO:0003964 RNA-directed DNA polymerase activity 1/221 13/18639 0.0769230769230769 6.48764357814132 0.143679449541185 0.625324033800962 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/221 13/18639 0.0769230769230769 6.48764357814132 0.143679449541185 0.625324033800962 GO:0035673 oligopeptide transmembrane transporter activity 1/221 13/18639 0.0769230769230769 6.48764357814132 0.143679449541185 0.625324033800962 GO:1902936 phosphatidylinositol bisphosphate binding 3/221 111/18639 0.027027027027027 2.27944233826587 0.145175406878743 0.625324033800962 GO:0061980 regulatory RNA binding 2/221 58/18639 0.0344827586206897 2.90825401778749 0.150712682115233 0.625324033800962 GO:0004705 JUN kinase activity 1/221 14/18639 0.0714285714285714 6.02424046541694 0.153839808268309 0.625324033800962 GO:0008195 phosphatidate phosphatase activity 1/221 14/18639 0.0714285714285714 6.02424046541694 0.153839808268309 0.625324033800962 GO:0008331 high voltage-gated calcium channel activity 1/221 14/18639 0.0714285714285714 6.02424046541694 0.153839808268309 0.625324033800962 GO:0008559 ABC-type xenobiotic transporter activity 1/221 14/18639 0.0714285714285714 6.02424046541694 0.153839808268309 0.625324033800962 GO:0034236 protein kinase A catalytic subunit binding 1/221 14/18639 0.0714285714285714 6.02424046541694 0.153839808268309 0.625324033800962 GO:0042813 Wnt receptor activity 1/221 14/18639 0.0714285714285714 6.02424046541694 0.153839808268309 0.625324033800962 GO:0043176 amine binding 1/221 14/18639 0.0714285714285714 6.02424046541694 0.153839808268309 0.625324033800962 GO:0044548 S100 protein binding 1/221 14/18639 0.0714285714285714 6.02424046541694 0.153839808268309 0.625324033800962 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/221 14/18639 0.0714285714285714 6.02424046541694 0.153839808268309 0.625324033800962 GO:0031593 polyubiquitin modification-dependent protein binding 2/221 59/18639 0.0338983050847458 2.85896157680804 0.154846642606408 0.625324033800962 GO:0001221 transcription coregulator binding 3/221 115/18639 0.0260869565217391 2.20015738736966 0.156373105339693 0.625324033800962 GO:0101005 deubiquitinase activity 3/221 115/18639 0.0260869565217391 2.20015738736966 0.156373105339693 0.625324033800962 GO:0001098 basal transcription machinery binding 2/221 60/18639 0.0333333333333333 2.81131221719457 0.159002311722375 0.625324033800962 GO:0001099 basal RNA polymerase II transcription machinery binding 2/221 60/18639 0.0333333333333333 2.81131221719457 0.159002311722375 0.625324033800962 GO:0043021 ribonucleoprotein complex binding 4/221 177/18639 0.0225988700564972 1.90597438453869 0.159256501418437 0.625324033800962 GO:0015026 coreceptor activity 2/221 61/18639 0.0327868852459016 2.76522513166679 0.163178600696484 0.625324033800962 GO:0004559 alpha-mannosidase activity 1/221 15/18639 0.0666666666666667 5.62262443438914 0.163880152019863 0.625324033800962 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/221 15/18639 0.0666666666666667 5.62262443438914 0.163880152019863 0.625324033800962 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/221 15/18639 0.0666666666666667 5.62262443438914 0.163880152019863 0.625324033800962 GO:0034483 heparan sulfate sulfotransferase activity 1/221 15/18639 0.0666666666666667 5.62262443438914 0.163880152019863 0.625324033800962 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/221 15/18639 0.0666666666666667 5.62262443438914 0.163880152019863 0.625324033800962 GO:0061578 K63-linked deubiquitinase activity 1/221 15/18639 0.0666666666666667 5.62262443438914 0.163880152019863 0.625324033800962 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/221 16/18639 0.0625 5.27121040723982 0.173801892054421 0.625324033800962 GO:0004707 MAP kinase activity 1/221 16/18639 0.0625 5.27121040723982 0.173801892054421 0.625324033800962 GO:0015562 efflux transmembrane transporter activity 1/221 16/18639 0.0625 5.27121040723982 0.173801892054421 0.625324033800962 GO:0015923 mannosidase activity 1/221 16/18639 0.0625 5.27121040723982 0.173801892054421 0.625324033800962 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/221 16/18639 0.0625 5.27121040723982 0.173801892054421 0.625324033800962 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/221 16/18639 0.0625 5.27121040723982 0.173801892054421 0.625324033800962 GO:0070411 I-SMAD binding 1/221 16/18639 0.0625 5.27121040723982 0.173801892054421 0.625324033800962 GO:0120013 lipid transfer activity 2/221 65/18639 0.0307692307692308 2.59505743125653 0.180068961172853 0.625324033800962 GO:0160215 deacylase activity 2/221 65/18639 0.0307692307692308 2.59505743125653 0.180068961172853 0.625324033800962 GO:0008234 cysteine-type peptidase activity 4/221 187/18639 0.0213903743315508 1.80405062065962 0.182319318623011 0.625324033800962 GO:0004549 tRNA-specific ribonuclease activity 1/221 17/18639 0.0588235294117647 4.96113920681395 0.183606423110426 0.625324033800962 GO:0008429 phosphatidylethanolamine binding 1/221 17/18639 0.0588235294117647 4.96113920681395 0.183606423110426 0.625324033800962 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/221 17/18639 0.0588235294117647 4.96113920681395 0.183606423110426 0.625324033800962 GO:0045125 bioactive lipid receptor activity 1/221 17/18639 0.0588235294117647 4.96113920681395 0.183606423110426 0.625324033800962 GO:0051787 misfolded protein binding 1/221 17/18639 0.0588235294117647 4.96113920681395 0.183606423110426 0.625324033800962 GO:0004519 endonuclease activity 3/221 127/18639 0.0236220472440945 1.9922685003741 0.191430157069737 0.625324033800962 GO:0019783 ubiquitin-like protein peptidase activity 3/221 127/18639 0.0236220472440945 1.9922685003741 0.191430157069737 0.625324033800962 GO:0030145 manganese ion binding 2/221 68/18639 0.0294117647058824 2.48056960340697 0.1929031645122 0.625324033800962 GO:0000400 four-way junction DNA binding 1/221 18/18639 0.0555555555555556 4.68552036199095 0.193295123598698 0.625324033800962 GO:0003746 translation elongation factor activity 1/221 18/18639 0.0555555555555556 4.68552036199095 0.193295123598698 0.625324033800962 GO:0032393 MHC class I receptor activity 1/221 18/18639 0.0555555555555556 4.68552036199095 0.193295123598698 0.625324033800962 GO:0050811 GABA receptor binding 1/221 18/18639 0.0555555555555556 4.68552036199095 0.193295123598698 0.625324033800962 GO:0070064 proline-rich region binding 1/221 18/18639 0.0555555555555556 4.68552036199095 0.193295123598698 0.625324033800962 GO:0031490 chromatin DNA binding 3/221 128/18639 0.0234375 1.97670390271493 0.194438164796473 0.625324033800962 GO:0003756 protein disulfide isomerase activity 1/221 19/18639 0.0526315789473684 4.43891402714932 0.202869355792709 0.625324033800962 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/221 19/18639 0.0526315789473684 4.43891402714932 0.202869355792709 0.625324033800962 GO:0008574 plus-end-directed microtubule motor activity 1/221 19/18639 0.0526315789473684 4.43891402714932 0.202869355792709 0.625324033800962 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/221 19/18639 0.0526315789473684 4.43891402714932 0.202869355792709 0.625324033800962 GO:0031420 alkali metal ion binding 1/221 19/18639 0.0526315789473684 4.43891402714932 0.202869355792709 0.625324033800962 GO:0042577 lipid phosphatase activity 1/221 19/18639 0.0526315789473684 4.43891402714932 0.202869355792709 0.625324033800962 GO:0046527 glucosyltransferase activity 1/221 19/18639 0.0526315789473684 4.43891402714932 0.202869355792709 0.625324033800962 GO:0097001 ceramide binding 1/221 19/18639 0.0526315789473684 4.43891402714932 0.202869355792709 0.625324033800962 GO:1990380 K48-linked deubiquitinase activity 1/221 19/18639 0.0526315789473684 4.43891402714932 0.202869355792709 0.625324033800962 GO:0031072 heat shock protein binding 3/221 131/18639 0.0229007633587786 1.93143587440848 0.203531429116052 0.625324033800962 GO:0005518 collagen binding 2/221 72/18639 0.0277777777777778 2.34276018099548 0.210189135504611 0.625324033800962 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/221 20/18639 0.05 4.21696832579186 0.212330466016652 0.625324033800962 GO:0015464 acetylcholine receptor activity 1/221 20/18639 0.05 4.21696832579186 0.212330466016652 0.625324033800962 GO:0016505 peptidase activator activity involved in apoptotic process 1/221 20/18639 0.05 4.21696832579186 0.212330466016652 0.625324033800962 GO:0042288 MHC class I protein binding 1/221 20/18639 0.05 4.21696832579186 0.212330466016652 0.625324033800962 GO:0043024 ribosomal small subunit binding 1/221 20/18639 0.05 4.21696832579186 0.212330466016652 0.625324033800962 GO:0052745 inositol phosphate phosphatase activity 1/221 20/18639 0.05 4.21696832579186 0.212330466016652 0.625324033800962 GO:0051087 protein-folding chaperone binding 3/221 134/18639 0.0223880597014925 1.88819477274262 0.212721702513206 0.625324033800962 GO:0003684 damaged DNA binding 2/221 74/18639 0.027027027027027 2.27944233826587 0.218890810763067 0.625324033800962 GO:0031491 nucleosome binding 2/221 74/18639 0.027027027027027 2.27944233826587 0.218890810763067 0.625324033800962 GO:0002020 protease binding 3/221 136/18639 0.0220588235294118 1.86042720255523 0.21889814985706 0.625324033800962 GO:0140789 histone phosphatase activity 3/221 136/18639 0.0220588235294118 1.86042720255523 0.21889814985706 0.625324033800962 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/221 21/18639 0.0476190476190476 4.01616031027796 0.22167978483132 0.625324033800962 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/221 21/18639 0.0476190476190476 4.01616031027796 0.22167978483132 0.625324033800962 GO:0019200 carbohydrate kinase activity 1/221 21/18639 0.0476190476190476 4.01616031027796 0.22167978483132 0.625324033800962 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/221 21/18639 0.0476190476190476 4.01616031027796 0.22167978483132 0.625324033800962 GO:0003714 transcription corepressor activity 4/221 204/18639 0.0196078431372549 1.65371306893798 0.223790480957789 0.625324033800962 GO:0008017 microtubule binding 5/221 276/18639 0.0181159420289855 1.52788707456227 0.230610270889377 0.625324033800962 GO:0008649 rRNA methyltransferase activity 1/221 22/18639 0.0454545454545455 3.83360756890169 0.230918627217843 0.625324033800962 GO:0070034 telomerase RNA binding 1/221 22/18639 0.0454545454545455 3.83360756890169 0.230918627217843 0.625324033800962 GO:0003724 RNA helicase activity 2/221 77/18639 0.025974025974026 2.19063289651525 0.231998252740995 0.625324033800962 GO:0004518 nuclease activity 4/221 209/18639 0.0191387559808612 1.61415055532703 0.236434625356309 0.625324033800962 GO:0003887 DNA-directed DNA polymerase activity 1/221 23/18639 0.0434782608695652 3.66692897894944 0.240048292759276 0.625324033800962 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/221 23/18639 0.0434782608695652 3.66692897894944 0.240048292759276 0.625324033800962 GO:0005283 amino acid:sodium symporter activity 1/221 23/18639 0.0434782608695652 3.66692897894944 0.240048292759276 0.625324033800962 GO:0042171 lysophosphatidic acid acyltransferase activity 1/221 23/18639 0.0434782608695652 3.66692897894944 0.240048292759276 0.625324033800962 GO:0043274 phospholipase binding 1/221 23/18639 0.0434782608695652 3.66692897894944 0.240048292759276 0.625324033800962 GO:0071617 lysophospholipid acyltransferase activity 1/221 23/18639 0.0434782608695652 3.66692897894944 0.240048292759276 0.625324033800962 GO:0140102 catalytic activity, acting on a rRNA 1/221 23/18639 0.0434782608695652 3.66692897894944 0.240048292759276 0.625324033800962 GO:0140103 catalytic activity, acting on a glycoprotein 1/221 23/18639 0.0434782608695652 3.66692897894944 0.240048292759276 0.625324033800962 GO:0008186 ATP-dependent activity, acting on RNA 2/221 79/18639 0.0253164556962025 2.13517383584398 0.240764178678671 0.625324033800962 GO:0000049 tRNA binding 2/221 80/18639 0.025 2.10848416289593 0.245153222013323 0.625324033800962 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/221 24/18639 0.0416666666666667 3.51414027149321 0.249070065820095 0.625324033800962 GO:0005315 phosphate transmembrane transporter activity 1/221 24/18639 0.0416666666666667 3.51414027149321 0.249070065820095 0.625324033800962 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/221 24/18639 0.0416666666666667 3.51414027149321 0.249070065820095 0.625324033800962 GO:0001618 virus receptor activity 2/221 81/18639 0.0246913580246914 2.0824534942182 0.249545375658525 0.625324033800962 GO:0033192 calmodulin-dependent protein phosphatase activity 2/221 81/18639 0.0246913580246914 2.0824534942182 0.249545375658525 0.625324033800962 GO:0140791 histone H2AXS140 phosphatase activity 2/221 81/18639 0.0246913580246914 2.0824534942182 0.249545375658525 0.625324033800962 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/221 81/18639 0.0246913580246914 2.0824534942182 0.249545375658525 0.625324033800962 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/221 81/18639 0.0246913580246914 2.0824534942182 0.249545375658525 0.625324033800962 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/221 81/18639 0.0246913580246914 2.0824534942182 0.249545375658525 0.625324033800962 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/221 81/18639 0.0246913580246914 2.0824534942182 0.249545375658525 0.625324033800962 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/221 81/18639 0.0246913580246914 2.0824534942182 0.249545375658525 0.625324033800962 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/221 81/18639 0.0246913580246914 2.0824534942182 0.249545375658525 0.625324033800962 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/221 82/18639 0.024390243902439 2.05705771989847 0.253939952230385 0.625324033800962 GO:0033549 MAP kinase phosphatase activity 2/221 82/18639 0.024390243902439 2.05705771989847 0.253939952230385 0.625324033800962 GO:0140272 exogenous protein binding 2/221 82/18639 0.024390243902439 2.05705771989847 0.253939952230385 0.625324033800962 GO:0008139 nuclear localization sequence binding 1/221 25/18639 0.04 3.37357466063348 0.2579852157236 0.625324033800962 GO:0017025 TBP-class protein binding 1/221 25/18639 0.04 3.37357466063348 0.2579852157236 0.625324033800962 GO:0017056 structural constituent of nuclear pore 1/221 25/18639 0.04 3.37357466063348 0.2579852157236 0.625324033800962 GO:0042974 nuclear retinoic acid receptor binding 1/221 25/18639 0.04 3.37357466063348 0.2579852157236 0.625324033800962 GO:0047617 fatty acyl-CoA hydrolase activity 1/221 25/18639 0.04 3.37357466063348 0.2579852157236 0.625324033800962 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/221 25/18639 0.04 3.37357466063348 0.2579852157236 0.625324033800962 GO:0120020 cholesterol transfer activity 1/221 25/18639 0.04 3.37357466063348 0.2579852157236 0.625324033800962 GO:0001540 amyloid-beta binding 2/221 83/18639 0.0240963855421687 2.03227389194788 0.258336280064035 0.625324033800962 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/221 83/18639 0.0240963855421687 2.03227389194788 0.258336280064035 0.625324033800962 GO:0042578 phosphoric ester hydrolase activity 6/221 363/18639 0.0165289256198347 1.39403911596425 0.262140416662204 0.625324033800962 GO:0017018 myosin phosphatase activity 2/221 84/18639 0.0238095238095238 2.00808015513898 0.262733702940409 0.625324033800962 GO:0051117 ATPase binding 2/221 84/18639 0.0238095238095238 2.00808015513898 0.262733702940409 0.625324033800962 GO:0000510 H3-H4 histone complex chaperone activity 3/221 151/18639 0.0198675496688742 1.67561655329478 0.266222529671162 0.625324033800962 GO:0140584 chromatin extrusion motor activity 3/221 151/18639 0.0198675496688742 1.67561655329478 0.266222529671162 0.625324033800962 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/221 151/18639 0.0198675496688742 1.67561655329478 0.266222529671162 0.625324033800962 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/221 151/18639 0.0198675496688742 1.67561655329478 0.266222529671162 0.625324033800962 GO:0005112 Notch binding 1/221 26/18639 0.0384615384615385 3.24382178907066 0.266794996927269 0.625324033800962 GO:0005160 transforming growth factor beta receptor binding 1/221 26/18639 0.0384615384615385 3.24382178907066 0.266794996927269 0.625324033800962 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/221 26/18639 0.0384615384615385 3.24382178907066 0.266794996927269 0.625324033800962 GO:0008143 poly(A) binding 1/221 26/18639 0.0384615384615385 3.24382178907066 0.266794996927269 0.625324033800962 GO:0016289 acyl-CoA hydrolase activity 1/221 26/18639 0.0384615384615385 3.24382178907066 0.266794996927269 0.625324033800962 GO:0034237 protein kinase A regulatory subunit binding 1/221 26/18639 0.0384615384615385 3.24382178907066 0.266794996927269 0.625324033800962 GO:0050681 nuclear androgen receptor binding 1/221 26/18639 0.0384615384615385 3.24382178907066 0.266794996927269 0.625324033800962 GO:0052742 phosphatidylinositol kinase activity 1/221 26/18639 0.0384615384615385 3.24382178907066 0.266794996927269 0.625324033800962 GO:0070412 R-SMAD binding 1/221 26/18639 0.0384615384615385 3.24382178907066 0.266794996927269 0.625324033800962 GO:0097602 cullin family protein binding 1/221 26/18639 0.0384615384615385 3.24382178907066 0.266794996927269 0.625324033800962 GO:0120014 phospholipid transfer activity 1/221 26/18639 0.0384615384615385 3.24382178907066 0.266794996927269 0.625324033800962 GO:0015616 DNA translocase activity 3/221 152/18639 0.0197368421052632 1.664592760181 0.269425972221887 0.625324033800962 GO:0140674 ATP-dependent histone chaperone activity 3/221 152/18639 0.0197368421052632 1.664592760181 0.269425972221887 0.625324033800962 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/221 86/18639 0.0232558139534884 1.96138061664737 0.271529284564302 0.625324033800962 GO:0050660 flavin adenine dinucleotide binding 2/221 86/18639 0.0232558139534884 1.96138061664737 0.271529284564302 0.625324033800962 GO:0003774 cytoskeletal motor activity 3/221 153/18639 0.0196078431372549 1.65371306893798 0.272633848451235 0.625324033800962 GO:0061775 cohesin loader activity 3/221 153/18639 0.0196078431372549 1.65371306893798 0.272633848451235 0.625324033800962 GO:0008266 poly(U) RNA binding 1/221 27/18639 0.037037037037037 3.1236802413273 0.275500649196064 0.625324033800962 GO:0023026 MHC class II protein complex binding 1/221 27/18639 0.037037037037037 3.1236802413273 0.275500649196064 0.625324033800962 GO:0004386 helicase activity 3/221 155/18639 0.0193548387096774 1.6323748357904 0.279061801108978 0.625324033800962 GO:0140375 immune receptor activity 3/221 156/18639 0.0192307692307692 1.62191089453533 0.282281333573644 0.625324033800962 GO:0046875 ephrin receptor binding 1/221 28/18639 0.0357142857142857 3.01212023270847 0.284103397773738 0.625324033800962 GO:0050698 proteoglycan sulfotransferase activity 1/221 28/18639 0.0357142857142857 3.01212023270847 0.284103397773738 0.625324033800962 GO:0051019 mitogen-activated protein kinase binding 1/221 28/18639 0.0357142857142857 3.01212023270847 0.284103397773738 0.625324033800962 GO:0051537 2 iron, 2 sulfur cluster binding 1/221 28/18639 0.0357142857142857 3.01212023270847 0.284103397773738 0.625324033800962 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/221 28/18639 0.0357142857142857 3.01212023270847 0.284103397773738 0.625324033800962 GO:0097718 disordered domain specific binding 1/221 28/18639 0.0357142857142857 3.01212023270847 0.284103397773738 0.625324033800962 GO:0003727 single-stranded RNA binding 2/221 89/18639 0.0224719101123595 1.89526666327724 0.284715322956464 0.625324033800962 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/221 89/18639 0.0224719101123595 1.89526666327724 0.284715322956464 0.625324033800962 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/221 89/18639 0.0224719101123595 1.89526666327724 0.284715322956464 0.625324033800962 GO:0140658 ATP-dependent chromatin remodeler activity 3/221 158/18639 0.0189873417721519 1.60138037688298 0.288730170395325 0.625324033800962 GO:0140793 histone H2AXY142 phosphatase activity 2/221 90/18639 0.0222222222222222 1.87420814479638 0.289106367079997 0.625324033800962 GO:0000287 magnesium ion binding 4/221 230/18639 0.0173913043478261 1.46677159157978 0.291125194147089 0.625324033800962 GO:0005525 GTP binding 6/221 378/18639 0.0158730158730159 1.33872010342599 0.292507708103723 0.625324033800962 GO:0003785 actin monomer binding 1/221 29/18639 0.0344827586206897 2.90825401778749 0.292604453552148 0.625324033800962 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/221 29/18639 0.0344827586206897 2.90825401778749 0.292604453552148 0.625324033800962 GO:0005416 amino acid:monoatomic cation symporter activity 1/221 29/18639 0.0344827586206897 2.90825401778749 0.292604453552148 0.625324033800962 GO:0051861 glycolipid binding 1/221 29/18639 0.0344827586206897 2.90825401778749 0.292604453552148 0.625324033800962 GO:0097472 cyclin-dependent protein kinase activity 1/221 29/18639 0.0344827586206897 2.90825401778749 0.292604453552148 0.625324033800962 GO:0106222 lncRNA binding 1/221 29/18639 0.0344827586206897 2.90825401778749 0.292604453552148 0.625324033800962 GO:0003689 DNA clamp loader activity 3/221 160/18639 0.01875 1.58136312217195 0.295190279877157 0.628316659979491 GO:0052689 carboxylic ester hydrolase activity 2/221 92/18639 0.0217391304347826 1.83346448947472 0.297878649071978 0.629804449742271 GO:0008187 poly-pyrimidine tract binding 1/221 30/18639 0.0333333333333333 2.81131221719457 0.301005013238606 0.629804449742271 GO:0033612 receptor serine/threonine kinase binding 1/221 30/18639 0.0333333333333333 2.81131221719457 0.301005013238606 0.629804449742271 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/221 30/18639 0.0333333333333333 2.81131221719457 0.301005013238606 0.629804449742271 GO:0140713 histone chaperone activity 3/221 164/18639 0.0182926829268293 1.54279328992385 0.308136076464301 0.629804449742271 GO:0005452 solute:inorganic anion antiporter activity 1/221 31/18639 0.032258064516129 2.72062472631733 0.30930625952128 0.629804449742271 GO:0008327 methyl-CpG binding 1/221 31/18639 0.032258064516129 2.72062472631733 0.30930625952128 0.629804449742271 GO:0016411 acylglycerol O-acyltransferase activity 1/221 31/18639 0.032258064516129 2.72062472631733 0.30930625952128 0.629804449742271 GO:0017147 Wnt-protein binding 1/221 31/18639 0.032258064516129 2.72062472631733 0.30930625952128 0.629804449742271 GO:0008276 protein methyltransferase activity 2/221 95/18639 0.0210526315789474 1.77556561085973 0.311004622653579 0.629804449742271 GO:0031369 translation initiation factor binding 1/221 32/18639 0.03125 2.63560520361991 0.317509361232683 0.629804449742271 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/221 32/18639 0.03125 2.63560520361991 0.317509361232683 0.629804449742271 GO:0042910 xenobiotic transmembrane transporter activity 1/221 32/18639 0.03125 2.63560520361991 0.317509361232683 0.629804449742271 GO:0070717 poly-purine tract binding 1/221 32/18639 0.03125 2.63560520361991 0.317509361232683 0.629804449742271 GO:0120015 sterol transfer activity 1/221 32/18639 0.03125 2.63560520361991 0.317509361232683 0.629804449742271 GO:0140142 nucleocytoplasmic carrier activity 1/221 32/18639 0.03125 2.63560520361991 0.317509361232683 0.629804449742271 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/221 167/18639 0.0179640718562874 1.51507844040426 0.317859924457152 0.629804449742271 GO:0004725 protein tyrosine phosphatase activity 2/221 98/18639 0.0204081632653061 1.7212115615477 0.324079651657235 0.629804449742271 GO:0008170 N-methyltransferase activity 2/221 98/18639 0.0204081632653061 1.7212115615477 0.324079651657235 0.629804449742271 GO:0042626 ATPase-coupled transmembrane transporter activity 2/221 98/18639 0.0204081632653061 1.7212115615477 0.324079651657235 0.629804449742271 GO:0019239 deaminase activity 1/221 33/18639 0.0303030303030303 2.55573837926779 0.325615473511265 0.629804449742271 GO:0140416 transcription regulator inhibitor activity 1/221 33/18639 0.0303030303030303 2.55573837926779 0.325615473511265 0.629804449742271 GO:0008175 tRNA methyltransferase activity 1/221 34/18639 0.0294117647058824 2.48056960340697 0.33362573796112 0.629804449742271 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/221 34/18639 0.0294117647058824 2.48056960340697 0.33362573796112 0.629804449742271 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/221 34/18639 0.0294117647058824 2.48056960340697 0.33362573796112 0.629804449742271 GO:0016831 carboxy-lyase activity 1/221 34/18639 0.0294117647058824 2.48056960340697 0.33362573796112 0.629804449742271 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/221 34/18639 0.0294117647058824 2.48056960340697 0.33362573796112 0.629804449742271 GO:0090482 vitamin transmembrane transporter activity 1/221 34/18639 0.0294117647058824 2.48056960340697 0.33362573796112 0.629804449742271 GO:0033218 amide binding 4/221 247/18639 0.0161943319838057 1.36581970066133 0.33655902144284 0.629804449742271 GO:0019001 guanyl nucleotide binding 6/221 400/18639 0.015 1.26509049773756 0.338209530281553 0.629804449742271 GO:0032561 guanyl ribonucleotide binding 6/221 400/18639 0.015 1.26509049773756 0.338209530281553 0.629804449742271 GO:0005154 epidermal growth factor receptor binding 1/221 35/18639 0.0285714285714286 2.40969618616677 0.341541282809849 0.629804449742271 GO:0005343 organic acid:sodium symporter activity 1/221 35/18639 0.0285714285714286 2.40969618616677 0.341541282809849 0.629804449742271 GO:0016229 steroid dehydrogenase activity 1/221 35/18639 0.0285714285714286 2.40969618616677 0.341541282809849 0.629804449742271 GO:0034061 DNA polymerase activity 1/221 35/18639 0.0285714285714286 2.40969618616677 0.341541282809849 0.629804449742271 GO:0140566 histone reader activity 1/221 35/18639 0.0285714285714286 2.40969618616677 0.341541282809849 0.629804449742271 GO:0042277 peptide binding 4/221 249/18639 0.0160642570281124 1.35484926129859 0.341935332401496 0.629804449742271 GO:0140104 molecular carrier activity 4/221 249/18639 0.0160642570281124 1.35484926129859 0.341935332401496 0.629804449742271 GO:0004721 phosphoprotein phosphatase activity 3/221 175/18639 0.0171428571428571 1.44581771170006 0.343798439229473 0.629804449742271 GO:0004722 protein serine/threonine phosphatase activity 2/221 103/18639 0.0194174757281553 1.63765760224926 0.345724364691961 0.629804449742271 GO:0004175 endopeptidase activity 6/221 405/18639 0.0148148148148148 1.24947209653092 0.34872435144699 0.629804449742271 GO:0000993 RNA polymerase II complex binding 1/221 36/18639 0.0277777777777778 2.34276018099548 0.34936322306458 0.629804449742271 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/221 36/18639 0.0277777777777778 2.34276018099548 0.34936322306458 0.629804449742271 GO:0005484 SNAP receptor activity 1/221 36/18639 0.0277777777777778 2.34276018099548 0.34936322306458 0.629804449742271 GO:0055106 ubiquitin-protein transferase regulator activity 1/221 36/18639 0.0277777777777778 2.34276018099548 0.34936322306458 0.629804449742271 GO:0005319 lipid transporter activity 3/221 178/18639 0.0168539325842697 1.42144999745793 0.353511037737847 0.635121525427318 GO:0019213 deacetylase activity 1/221 37/18639 0.027027027027027 2.27944233826587 0.357092660666189 0.637236061121482 GO:0023023 MHC protein complex binding 1/221 37/18639 0.027027027027027 2.27944233826587 0.357092660666189 0.637236061121482 GO:0030695 GTPase regulator activity 7/221 489/18639 0.0143149284253579 1.20731199511423 0.360623747450541 0.641377805868413 GO:0060589 nucleoside-triphosphatase regulator activity 7/221 490/18639 0.0142857142857143 1.20484809308339 0.362557714524906 0.642660831766557 GO:0042887 amide transmembrane transporter activity 1/221 38/18639 0.0263157894736842 2.21945701357466 0.364730684641717 0.644357542867034 GO:0016887 ATP hydrolysis activity 6/221 417/18639 0.0143884892086331 1.21351606497607 0.37406506665745 0.655731301328652 GO:0004222 metalloendopeptidase activity 2/221 110/18639 0.0181818181818182 1.53344302756067 0.375632156785719 0.655731301328652 GO:1901981 phosphatidylinositol phosphate binding 3/221 185/18639 0.0162162162162162 1.36766540295952 0.376098762565494 0.655731301328652 GO:0005543 phospholipid binding 7/221 497/18639 0.0140845070422535 1.18787840163151 0.376117576611151 0.655731301328652 GO:0004177 aminopeptidase activity 1/221 40/18639 0.025 2.10848416289593 0.379736784155707 0.657714037916747 GO:0032451 demethylase activity 1/221 40/18639 0.025 2.10848416289593 0.379736784155707 0.657714037916747 GO:0043022 ribosome binding 2/221 112/18639 0.0178571428571429 1.50606011635423 0.384077290929148 0.659390189433964 GO:0140597 protein carrier chaperone 3/221 188/18639 0.0159574468085106 1.34584095503995 0.385734191159883 0.659390189433964 GO:0001727 lipid kinase activity 1/221 41/18639 0.024390243902439 2.05705771989847 0.387106974526242 0.659390189433964 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/221 41/18639 0.024390243902439 2.05705771989847 0.387106974526242 0.659390189433964 GO:0042287 MHC protein binding 1/221 41/18639 0.024390243902439 2.05705771989847 0.387106974526242 0.659390189433964 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 4/221 268/18639 0.0149253731343284 1.25879651516175 0.392999797754996 0.659390189433964 GO:0004520 DNA endonuclease activity 1/221 42/18639 0.0238095238095238 2.00808015513898 0.394389981227484 0.659390189433964 GO:0031492 nucleosomal DNA binding 1/221 42/18639 0.0238095238095238 2.00808015513898 0.394389981227484 0.659390189433964 GO:0035198 miRNA binding 1/221 42/18639 0.0238095238095238 2.00808015513898 0.394389981227484 0.659390189433964 GO:0043175 RNA polymerase core enzyme binding 1/221 42/18639 0.0238095238095238 2.00808015513898 0.394389981227484 0.659390189433964 GO:0048487 beta-tubulin binding 1/221 42/18639 0.0238095238095238 2.00808015513898 0.394389981227484 0.659390189433964 GO:0017124 SH3 domain binding 2/221 115/18639 0.0173913043478261 1.46677159157978 0.396651980108101 0.661086633513501 GO:0005245 voltage-gated calcium channel activity 1/221 43/18639 0.0232558139534884 1.96138061664737 0.401586830942423 0.663056138316151 GO:0008375 acetylglucosaminyltransferase activity 1/221 43/18639 0.0232558139534884 1.96138061664737 0.401586830942423 0.663056138316151 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/221 43/18639 0.0232558139534884 1.96138061664737 0.401586830942423 0.663056138316151 GO:0061630 ubiquitin protein ligase activity 5/221 353/18639 0.0141643059490085 1.19460859087588 0.40788180562165 0.664448543891708 GO:0001223 transcription coactivator binding 1/221 44/18639 0.0227272727272727 1.91680378445084 0.408698538318296 0.664448543891708 GO:0016790 thiolester hydrolase activity 1/221 44/18639 0.0227272727272727 1.91680378445084 0.408698538318296 0.664448543891708 GO:0019205 nucleobase-containing compound kinase activity 1/221 44/18639 0.0227272727272727 1.91680378445084 0.408698538318296 0.664448543891708 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/221 44/18639 0.0227272727272727 1.91680378445084 0.408698538318296 0.664448543891708 GO:0042605 peptide antigen binding 1/221 45/18639 0.0222222222222222 1.87420814479638 0.415726106107038 0.673806838644434 GO:0001217 DNA-binding transcription repressor activity 4/221 278/18639 0.0143884892086331 1.21351606497607 0.419685924215429 0.678151036079809 GO:0003697 single-stranded DNA binding 2/221 121/18639 0.0165289256198347 1.39403911596425 0.421438417282538 0.678834480033872 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/221 46/18639 0.0217391304347826 1.83346448947472 0.422670525304109 0.678834480033872 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/221 122/18639 0.0163934426229508 1.3826125658334 0.425519422013766 0.681345298088508 GO:0005504 fatty acid binding 1/221 47/18639 0.0212765957446809 1.79445460671994 0.429532775285704 0.683640753457727 GO:0140938 histone H3 methyltransferase activity 1/221 47/18639 0.0212765957446809 1.79445460671994 0.429532775285704 0.683640753457727 GO:0035091 phosphatidylinositol binding 4/221 284/18639 0.0140845070422535 1.18787840163151 0.435572047072571 0.688417964063548 GO:0032266 phosphatidylinositol-3-phosphate binding 1/221 48/18639 0.0208333333333333 1.75707013574661 0.436313823944367 0.688417964063548 GO:0008168 methyltransferase activity 3/221 204/18639 0.0147058823529412 1.24028480170349 0.43643101117991 0.688417964063548 GO:0001222 transcription corepressor binding 1/221 49/18639 0.0204081632653061 1.7212115615477 0.443014627823034 0.694667907533159 GO:0035254 glutamate receptor binding 1/221 49/18639 0.0204081632653061 1.7212115615477 0.443014627823034 0.694667907533159 GO:0015605 organophosphate ester transmembrane transporter activity 1/221 50/18639 0.02 1.68678733031674 0.449636132247515 0.70028174465233 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/221 128/18639 0.015625 1.31780260180995 0.449684309762218 0.70028174465233 GO:0051015 actin filament binding 3/221 209/18639 0.0143540669856459 1.21061291649527 0.451967837103256 0.70028174465233 GO:0061659 ubiquitin-like protein ligase activity 5/221 372/18639 0.0134408602150538 1.13359363596555 0.452118033524749 0.70028174465233 GO:0008094 ATP-dependent activity, acting on DNA 3/221 210/18639 0.0142857142857143 1.20484809308339 0.455054558384985 0.70028174465233 GO:0005048 signal sequence binding 1/221 51/18639 0.0196078431372549 1.65371306893798 0.45617927145744 0.70028174465233 GO:0016830 carbon-carbon lyase activity 1/221 51/18639 0.0196078431372549 1.65371306893798 0.45617927145744 0.70028174465233 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/221 130/18639 0.0153846153846154 1.29752871562826 0.457612116985552 0.70028174465233 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/221 52/18639 0.0192307692307692 1.62191089453533 0.462644968735679 0.70028174465233 GO:0030159 signaling receptor complex adaptor activity 1/221 52/18639 0.0192307692307692 1.62191089453533 0.462644968735679 0.70028174465233 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/221 132/18639 0.0151515151515152 1.2778691896339 0.465473919311455 0.70028174465233 GO:0008146 sulfotransferase activity 1/221 53/18639 0.0188679245283019 1.59130880218561 0.469034136536261 0.70028174465233 GO:0051018 protein kinase A binding 1/221 53/18639 0.0188679245283019 1.59130880218561 0.469034136536261 0.70028174465233 GO:0140296 general transcription initiation factor binding 1/221 53/18639 0.0188679245283019 1.59130880218561 0.469034136536261 0.70028174465233 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/221 53/18639 0.0188679245283019 1.59130880218561 0.469034136536261 0.70028174465233 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/221 53/18639 0.0188679245283019 1.59130880218561 0.469034136536261 0.70028174465233 GO:0001664 G protein-coupled receptor binding 4/221 297/18639 0.0134680134680135 1.13588372411902 0.469550689634521 0.70028174465233 GO:0016741 transferase activity, transferring one-carbon groups 3/221 215/18639 0.013953488372093 1.17682836998842 0.470377926596659 0.70028174465233 GO:0016779 nucleotidyltransferase activity 2/221 136/18639 0.0147058823529412 1.24028480170349 0.480994399063694 0.711432345274623 GO:0008374 O-acyltransferase activity 1/221 55/18639 0.0181818181818182 1.53344302756067 0.481586480133486 0.711432345274623 GO:0015631 tubulin binding 5/221 385/18639 0.012987012987013 1.09531644825762 0.481894739535075 0.711432345274623 GO:0016922 nuclear receptor binding 2/221 137/18639 0.0145985401459854 1.23123162796842 0.484831348683871 0.71214395798073 GO:0140098 catalytic activity, acting on RNA 5/221 387/18639 0.0129198966408269 1.08965589813743 0.486429385872385 0.71214395798073 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/221 56/18639 0.0178571428571429 1.50606011635423 0.487751427824537 0.71214395798073 GO:0170055 lipid transmembrane transporter activity 1/221 56/18639 0.0178571428571429 1.50606011635423 0.487751427824537 0.71214395798073 GO:0070851 growth factor receptor binding 2/221 139/18639 0.0143884892086331 1.21351606497607 0.49245251098659 0.715068029651761 GO:0140101 catalytic activity, acting on a tRNA 2/221 139/18639 0.0143884892086331 1.21351606497607 0.49245251098659 0.715068029651761 GO:0016504 peptidase activator activity 1/221 57/18639 0.0175438596491228 1.47963800904977 0.493843390072332 0.715128406388897 GO:0017116 single-stranded DNA helicase activity 1/221 58/18639 0.0172413793103448 1.45412700889374 0.499863227054036 0.720645828207189 GO:0061134 peptidase regulator activity 3/221 226/18639 0.0132743362831858 1.11954911304209 0.503385181366853 0.720645828207189 GO:0001786 phosphatidylserine binding 1/221 59/18639 0.0169491525423729 1.42948078840402 0.505811788854857 0.720645828207189 GO:0004879 nuclear receptor activity 1/221 59/18639 0.0169491525423729 1.42948078840402 0.505811788854857 0.720645828207189 GO:0036002 pre-mRNA binding 1/221 59/18639 0.0169491525423729 1.42948078840402 0.505811788854857 0.720645828207189 GO:0070063 RNA polymerase binding 1/221 59/18639 0.0169491525423729 1.42948078840402 0.505811788854857 0.720645828207189 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/221 60/18639 0.0166666666666667 1.40565610859728 0.511689915585916 0.725122072889133 GO:0098531 ligand-modulated transcription factor activity 1/221 60/18639 0.0166666666666667 1.40565610859728 0.511689915585916 0.725122072889133 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 6/221 484/18639 0.012396694214876 1.04552933697319 0.513838397307284 0.726109892875978 GO:0005085 guanyl-nucleotide exchange factor activity 3/221 230/18639 0.0130434782608696 1.10007869368483 0.515127018342203 0.726109892875978 GO:0015179 L-amino acid transmembrane transporter activity 1/221 62/18639 0.0161290322580645 1.36031236315866 0.523238175110404 0.733827926250228 GO:0001216 DNA-binding transcription activator activity 6/221 491/18639 0.0122199592668024 1.03062362341145 0.527883119403951 0.733827926250228 GO:0005507 copper ion binding 1/221 63/18639 0.0158730158730159 1.33872010342599 0.528909939297334 0.733827926250228 GO:0022824 transmitter-gated monoatomic ion channel activity 1/221 63/18639 0.0158730158730159 1.33872010342599 0.528909939297334 0.733827926250228 GO:0022835 transmitter-gated channel activity 1/221 63/18639 0.0158730158730159 1.33872010342599 0.528909939297334 0.733827926250228 GO:1901682 sulfur compound transmembrane transporter activity 1/221 63/18639 0.0158730158730159 1.33872010342599 0.528909939297334 0.733827926250228 GO:0004536 DNA nuclease activity 1/221 64/18639 0.015625 1.31780260180995 0.534514531427787 0.739667628346546 GO:0019843 rRNA binding 1/221 65/18639 0.0153846153846154 1.29752871562826 0.54005274346302 0.743449231260781 GO:0038024 cargo receptor activity 1/221 65/18639 0.0153846153846154 1.29752871562826 0.54005274346302 0.743449231260781 GO:0004857 enzyme inhibitor activity 5/221 416/18639 0.0120192307692308 1.01369430908458 0.550425113125909 0.750628711631638 GO:0008173 RNA methyltransferase activity 1/221 67/18639 0.0149253731343284 1.25879651516175 0.550933148725863 0.750628711631638 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/221 67/18639 0.0149253731343284 1.25879651516175 0.550933148725863 0.750628711631638 GO:0042054 histone methyltransferase activity 1/221 67/18639 0.0149253731343284 1.25879651516175 0.550933148725863 0.750628711631638 GO:0003777 microtubule motor activity 1/221 68/18639 0.0147058823529412 1.24028480170349 0.556276879833529 0.75403259926284 GO:0005548 phospholipid transporter activity 1/221 68/18639 0.0147058823529412 1.24028480170349 0.556276879833529 0.75403259926284 GO:0016279 protein-lysine N-methyltransferase activity 1/221 69/18639 0.0144927536231884 1.22230965964981 0.561557306819518 0.757316469756602 GO:0098960 postsynaptic neurotransmitter receptor activity 1/221 69/18639 0.0144927536231884 1.22230965964981 0.561557306819518 0.757316469756602 GO:0140097 catalytic activity, acting on DNA 4/221 336/18639 0.0119047619047619 1.00404007756949 0.566276637707931 0.758562735880698 GO:0016278 lysine N-methyltransferase activity 1/221 70/18639 0.0142857142857143 1.20484809308339 0.566775176242937 0.758562735880698 GO:0016782 transferase activity, transferring sulphur-containing groups 1/221 70/18639 0.0142857142857143 1.20484809308339 0.566775176242937 0.758562735880698 GO:0004866 endopeptidase inhibitor activity 2/221 161/18639 0.0124223602484472 1.04769399398555 0.571432411963668 0.76286946685326 GO:0004521 RNA endonuclease activity 1/221 73/18639 0.0136986301369863 1.15533378788818 0.582060773873227 0.769612763168055 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/221 73/18639 0.0136986301369863 1.15533378788818 0.582060773873227 0.769612763168055 GO:0043539 protein serine/threonine kinase activator activity 1/221 73/18639 0.0136986301369863 1.15533378788818 0.582060773873227 0.769612763168055 GO:0015103 inorganic anion transmembrane transporter activity 2/221 165/18639 0.0121212121212121 1.02229535170712 0.584805348317552 0.769612763168055 GO:0004674 protein serine/threonine kinase activity 5/221 433/18639 0.0115473441108545 0.973895687249851 0.586119820898686 0.769612763168055 GO:0003678 DNA helicase activity 1/221 74/18639 0.0135135135135135 1.13972116913293 0.587035704874736 0.769612763168055 GO:0048029 monosaccharide binding 1/221 74/18639 0.0135135135135135 1.13972116913293 0.587035704874736 0.769612763168055 GO:0015399 primary active transmembrane transporter activity 2/221 166/18639 0.0120481927710843 1.01613694597394 0.588100319024646 0.769612763168055 GO:0005201 extracellular matrix structural constituent 2/221 168/18639 0.0119047619047619 1.00404007756949 0.594632264861237 0.774744966762829 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 4/221 349/18639 0.0114613180515759 0.966640303906442 0.596321604509638 0.774744966762829 GO:0051536 iron-sulfur cluster binding 1/221 76/18639 0.0131578947368421 1.10972850678733 0.596809399746347 0.774744966762829 GO:0030414 peptidase inhibitor activity 2/221 169/18639 0.0118343195266272 0.998099012021741 0.597869229067919 0.774744966762829 GO:0051540 metal cluster binding 1/221 77/18639 0.012987012987013 1.09531644825762 0.60160954641747 0.777690389271364 GO:0003730 mRNA 3'-UTR binding 3/221 262/18639 0.0114503816793893 0.965717937204242 0.603350683757325 0.778043460806283 GO:0140030 modification-dependent protein binding 2/221 173/18639 0.0115606936416185 0.97502157821777 0.610623697178149 0.780364126048646 GO:0015370 solute:sodium symporter activity 1/221 79/18639 0.0126582278481013 1.06758691792199 0.611039834547525 0.780364126048646 GO:0016835 carbon-oxygen lyase activity 1/221 79/18639 0.0126582278481013 1.06758691792199 0.611039834547525 0.780364126048646 GO:0033293 monocarboxylic acid binding 1/221 79/18639 0.0126582278481013 1.06758691792199 0.611039834547525 0.780364126048646 GO:0048306 calcium-dependent protein binding 1/221 80/18639 0.0125 1.05424208144796 0.615671310655552 0.783882966186786 GO:0022832 voltage-gated channel activity 2/221 175/18639 0.0114285714285714 0.96387847446671 0.616884983403397 0.783882966186786 GO:0004842 ubiquitin-protein transferase activity 5/221 449/18639 0.0111358574610245 0.939191163873464 0.618280765037765 0.783882966186786 GO:0015101 organic cation transmembrane transporter activity 1/221 81/18639 0.0123456790123457 1.0412267471091 0.620247884843015 0.783882966186786 GO:0008514 organic anion transmembrane transporter activity 3/221 269/18639 0.0111524163568773 0.940587730659893 0.621190275091416 0.783882966186786 GO:0106310 protein serine kinase activity 4/221 361/18639 0.0110803324099723 0.934508216241962 0.62293745117767 0.784220544237921 GO:0005096 GTPase activator activity 3/221 271/18639 0.011070110701107 0.933646123791555 0.626186581091499 0.786442862508281 GO:0004527 exonuclease activity 1/221 84/18639 0.0119047619047619 1.00404007756949 0.633654636803501 0.793940797886184 GO:0046982 protein heterodimerization activity 4/221 369/18639 0.010840108401084 0.914247875510429 0.640059280190734 0.800074100238418 GO:0008237 metallopeptidase activity 2/221 184/18639 0.0108695652173913 0.91673224473736 0.64410812793239 0.801355182638889 GO:0061135 endopeptidase regulator activity 2/221 184/18639 0.0108695652173913 0.91673224473736 0.64410812793239 0.801355182638889 GO:0031267 small GTPase binding 3/221 283/18639 0.0106007067137809 0.894056888860464 0.655213447760332 0.811977774125664 GO:0046943 carboxylic acid transmembrane transporter activity 2/221 188/18639 0.0106382978723404 0.897227303359969 0.655710353444876 0.811977774125664 GO:0005342 organic acid transmembrane transporter activity 2/221 189/18639 0.0105820105820106 0.892480068950657 0.658563527144013 0.81360995194948 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/221 91/18639 0.010989010989011 0.92680622544876 0.663132858661296 0.815273278411312 GO:0072341 modified amino acid binding 1/221 91/18639 0.010989010989011 0.92680622544876 0.663132858661296 0.815273278411312 GO:0019207 kinase regulator activity 3/221 287/18639 0.0104529616724739 0.881596165670771 0.664524634478655 0.815273278411312 GO:0019787 ubiquitin-like protein transferase activity 5/221 479/18639 0.0104384133611691 0.880369170311452 0.674465334709635 0.824347757048112 GO:0042562 hormone binding 1/221 94/18639 0.0106382978723404 0.897227303359969 0.675031936903548 0.824347757048112 GO:0004867 serine-type endopeptidase inhibitor activity 1/221 95/18639 0.0105263157894737 0.887782805429864 0.678904567906207 0.827171082736299 GO:0016758 hexosyltransferase activity 2/221 197/18639 0.0101522842639594 0.856237223511036 0.680713479723491 0.827472807920758 GO:0004896 cytokine receptor activity 1/221 96/18639 0.0104166666666667 0.878535067873303 0.682731255271001 0.828026465202816 GO:0030594 neurotransmitter receptor activity 1/221 97/18639 0.0103092783505155 0.869478005317908 0.686512541610056 0.830711522952808 GO:0016829 lyase activity 2/221 200/18639 0.01 0.843393665158371 0.688713450178376 0.831476374930614 GO:0031625 ubiquitin protein ligase binding 3/221 302/18639 0.00993377483443709 0.837808276647389 0.697814813910179 0.840549662209989 GO:0016755 aminoacyltransferase activity 5/221 496/18639 0.0100806451612903 0.850195226974164 0.703784810923137 0.843162412357596 GO:0008238 exopeptidase activity 1/221 102/18639 0.00980392156862745 0.826856534468991 0.704756506932858 0.843162412357596 GO:0015171 amino acid transmembrane transporter activity 1/221 102/18639 0.00980392156862745 0.826856534468991 0.704756506932858 0.843162412357596 GO:0000149 SNARE binding 1/221 106/18639 0.00943396226415094 0.795654401092803 0.718587503970549 0.85392685449415 GO:0004497 monooxygenase activity 1/221 106/18639 0.00943396226415094 0.795654401092803 0.718587503970549 0.85392685449415 GO:0008013 beta-catenin binding 1/221 106/18639 0.00943396226415094 0.795654401092803 0.718587503970549 0.85392685449415 GO:0051020 GTPase binding 3/221 315/18639 0.00952380952380952 0.803232062055592 0.724602890996198 0.859148841673345 GO:0022836 gated channel activity 3/221 318/18639 0.00943396226415094 0.795654401092803 0.730516176528816 0.86406179426078 GO:0005200 structural constituent of cytoskeleton 1/221 112/18639 0.00892857142857143 0.753030058177117 0.738133792355603 0.86406179426078 GO:0044389 ubiquitin-like protein ligase binding 3/221 322/18639 0.0093167701863354 0.785770495489166 0.738245768067267 0.86406179426078 GO:0015294 solute:monoatomic cation symporter activity 1/221 116/18639 0.00862068965517241 0.727063504446872 0.750407697954754 0.86406179426078 GO:0003924 GTPase activity 3/221 331/18639 0.00906344410876133 0.764405134584626 0.754998149701195 0.86406179426078 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/221 229/18639 0.00873362445414847 0.736588353850106 0.757820120422805 0.86406179426078 GO:0004540 RNA nuclease activity 1/221 121/18639 0.00826446280991736 0.697019557982125 0.7649477155229 0.86406179426078 GO:0051082 unfolded protein binding 1/221 121/18639 0.00826446280991736 0.697019557982125 0.7649477155229 0.86406179426078 GO:0008528 G protein-coupled peptide receptor activity 1/221 122/18639 0.00819672131147541 0.691306282916698 0.76775290803124 0.86406179426078 GO:0005261 monoatomic cation channel activity 3/221 341/18639 0.00879765395894428 0.741988561722907 0.772593971053934 0.86406179426078 GO:0042826 histone deacetylase binding 1/221 127/18639 0.0078740157480315 0.664089500124702 0.781286758889589 0.86406179426078 GO:0001653 peptide receptor activity 1/221 128/18639 0.0078125 0.658901300904977 0.783897801796104 0.86406179426078 GO:0046873 metal ion transmembrane transporter activity 4/221 450/18639 0.00888888888888889 0.749683257918552 0.784125256270454 0.86406179426078 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 2/221 243/18639 0.00823045267489712 0.6941511647394 0.786185708088849 0.86406179426078 GO:0035591 signaling adaptor activity 1/221 129/18639 0.00775193798449612 0.653793538882458 0.786477812913983 0.86406179426078 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/221 130/18639 0.00769230769230769 0.648764357814132 0.789027159394048 0.86406179426078 GO:0004676 3-phosphoinositide-dependent protein kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0004711 ribosomal protein S6 kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0035175 histone H3S10 kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0035979 histone H2AXS139 kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0044022 histone H3S28 kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0044023 histone H4S1 kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0044024 histone H2AS1 kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0044025 histone H2BS14 kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0072354 histone H3T3 kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0072371 histone H2AS121 kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0072518 Rho-dependent protein serine/threonine kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0140823 histone H2BS36 kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0140855 histone H3S57 kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0140995 histone H2A kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0140997 histone H4 kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0140998 histone H2B kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:1990244 histone H2AT120 kinase activity 2/221 245/18639 0.00816326530612245 0.688484624619078 0.78999160418327 0.86406179426078 GO:0005262 calcium channel activity 1/221 131/18639 0.00763358778625954 0.643811958136161 0.7915462040628 0.86406179426078 GO:0004677 DNA-dependent protein kinase activity 2/221 246/18639 0.00813008130081301 0.685685906632822 0.79187217244381 0.86406179426078 GO:0140857 histone H3T45 kinase activity 2/221 246/18639 0.00813008130081301 0.685685906632822 0.79187217244381 0.86406179426078 GO:0035402 histone H3T11 kinase activity 2/221 247/18639 0.00809716599190283 0.682909850330665 0.793737933730878 0.86406179426078 GO:0035403 histone H3T6 kinase activity 2/221 247/18639 0.00809716599190283 0.682909850330665 0.793737933730878 0.86406179426078 GO:0042393 histone binding 2/221 247/18639 0.00809716599190283 0.682909850330665 0.793737933730878 0.86406179426078 GO:0022804 active transmembrane transporter activity 4/221 457/18639 0.0087527352297593 0.738200144558749 0.794107360610738 0.86406179426078 GO:0004679 AMP-activated protein kinase activity 2/221 248/18639 0.00806451612903226 0.680156181579331 0.795588972828794 0.86406179426078 GO:0015297 antiporter activity 1/221 135/18639 0.00740740740740741 0.62473604826546 0.801326472626132 0.867536925630049 GO:0044325 transmembrane transporter binding 1/221 136/18639 0.00735294117647059 0.620142400851743 0.803699302800668 0.867536925630049 GO:0099094 ligand-gated monoatomic cation channel activity 1/221 136/18639 0.00735294117647059 0.620142400851743 0.803699302800668 0.867536925630049 GO:0019887 protein kinase regulator activity 2/221 255/18639 0.00784313725490196 0.661485227575193 0.808141160487417 0.869725545396261 GO:0003713 transcription coactivator activity 2/221 256/18639 0.0078125 0.658901300904977 0.809877481090333 0.869725545396261 GO:0030295 protein kinase activator activity 1/221 139/18639 0.00719424460431655 0.606758032488037 0.810649847973119 0.869725545396261 GO:0020037 heme binding 1/221 142/18639 0.00704225352112676 0.593939200815754 0.817355364942475 0.875148168524266 GO:0022843 voltage-gated monoatomic cation channel activity 1/221 143/18639 0.00699300699300699 0.589785779831029 0.819537581753185 0.875715561147557 GO:0019955 cytokine binding 1/221 144/18639 0.00694444444444444 0.585690045248869 0.821693842265326 0.876006964546601 GO:0008194 UDP-glycosyltransferase activity 1/221 145/18639 0.00689655172413793 0.581650803557497 0.823824453828416 0.876006964546601 GO:0015293 symporter activity 1/221 146/18639 0.00684931506849315 0.57766689394409 0.825929720169063 0.876006964546601 GO:0015085 calcium ion transmembrane transporter activity 1/221 147/18639 0.00680272108843537 0.573737187182565 0.828009941433468 0.876006964546601 GO:0016757 glycosyltransferase activity 2/221 267/18639 0.00749063670411985 0.631755554425746 0.828074507995938 0.876006964546601 GO:0019209 kinase activator activity 1/221 148/18639 0.00675675675675676 0.569860584566467 0.830065414229445 0.876363883549015 GO:0140297 DNA-binding transcription factor binding 4/221 488/18639 0.00819672131147541 0.691306282916698 0.833947554055051 0.878712134491406 GO:0046906 tetrapyrrole binding 1/221 152/18639 0.00657894736842105 0.554864253393665 0.838045631353608 0.881278144082167 GO:0005126 cytokine receptor binding 2/221 275/18639 0.00727272727272727 0.61337721102427 0.840312249236397 0.88182647252561 GO:0005506 iron ion binding 1/221 154/18639 0.00649350649350649 0.547658224128812 0.841894707731997 0.88182647252561 GO:0030246 carbohydrate binding 2/221 280/18639 0.00714285714285714 0.602424046541694 0.847556452194322 0.886005758704123 GO:0005178 integrin binding 1/221 161/18639 0.0062111801242236 0.523846996992777 0.854663217697815 0.891676191692602 GO:0015291 secondary active transmembrane transporter activity 2/221 287/18639 0.00696864111498258 0.587730777113847 0.857198744322145 0.892564507840347 GO:0015081 sodium ion transmembrane transporter activity 1/221 164/18639 0.00609756097560976 0.514264429974617 0.859816129866532 0.893534409469141 GO:0016874 ligase activity 1/221 167/18639 0.00598802395209581 0.50502614680142 0.864787143078004 0.896941655247245 GO:0005244 voltage-gated monoatomic ion channel activity 1/221 173/18639 0.00578034682080925 0.487510789108885 0.874208820600799 0.904942724450045 GO:0004252 serine-type endopeptidase activity 1/221 176/18639 0.00568181818181818 0.479200946112711 0.878671607460914 0.907789380027845 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/221 181/18639 0.00552486187845304 0.465963350916227 0.885762023441215 0.913334382147556 GO:0015276 ligand-gated monoatomic ion channel activity 1/221 186/18639 0.00537634408602151 0.453437454386221 0.892439841733278 0.917021234231405 GO:0031406 carboxylic acid binding 1/221 187/18639 0.0053475935828877 0.451012655164904 0.893728022244682 0.917021234231405 GO:0022834 ligand-gated channel activity 1/221 188/18639 0.00531914893617021 0.448613651679985 0.89500084400297 0.917021234231405 GO:0043177 organic acid binding 1/221 189/18639 0.00529100529100529 0.446240034475329 0.896258489305411 0.917021234231405 GO:0003779 actin binding 3/221 443/18639 0.00677200902934537 0.571146951574518 0.899253197499075 0.918312513823718 GO:0008236 serine-type peptidase activity 1/221 194/18639 0.00515463917525773 0.434739002658954 0.902325300016758 0.919013291799092 GO:0005216 monoatomic ion channel activity 3/221 448/18639 0.00669642857142857 0.564772543632838 0.903407405711938 0.919013291799092 GO:0017171 serine hydrolase activity 1/221 198/18639 0.00505050505050505 0.425956396544632 0.90692338914139 0.920822598170377 GO:0005516 calmodulin binding 1/221 207/18639 0.00483091787439614 0.407436553216604 0.916496358004667 0.928763039660561 GO:0141003 histone H2AX kinase activity 2/221 354/18639 0.00564971751412429 0.476493596134673 0.924955256184273 0.93554634690394 GO:0140996 histone H3 kinase activity 2/221 357/18639 0.00560224089635854 0.472489448267995 0.927135705270245 0.935965569129962 GO:0035173 histone kinase activity 2/221 360/18639 0.00555555555555556 0.468552036199095 0.929256502968715 0.936323092344903 GO:0005125 cytokine activity 1/221 234/18639 0.00427350427350427 0.360424643230073 0.939721708033644 0.945071167472166 GO:0005539 glycosaminoglycan binding 1/221 242/18639 0.00413223140495868 0.348509778991062 0.94527551123013 0.94885610028782 GO:0030371 translation repressor activity 1/221 329/18639 0.00303951367781155 0.256350658102848 0.980924843066864 0.982779143337312 GO:0045182 translation regulator activity 1/221 356/18639 0.00280898876404494 0.236908332909655 0.986260399750986 0.986260399750986