category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	23/68	238/9376	13.3247652001977	RPL13A/RPS11/RPS8/RPS20/RPS26/RPS2/F13A1/RPL27A/RPS14/RPL7/RPL18A/RPLP2/RPS5/RPL23/RPL13/RPL8/RPLP0/RPS15/C7/RPS27A/UBA52/RPSA/RPL10	16.46089570144
Genetic Information Processing	Translation	hsa03010	Ribosome	21/68	222/9376	13.0429252782194	RPL13A/RPS11/RPS8/RPS20/RPS26/RPS2/RPL27A/RPS14/RPL7/RPL18A/RPLP2/RPS5/RPL23/RPL13/RPL8/RPLP0/RPS15/RPS27A/UBA52/RPSA/RPL10	15.520829644514
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	18/68	205/9376	12.1067431850789	MT-ND4/MT-CYB/MT-ND1/MT-CO3/MT-ATP6/MT-ND2/MT-CO2/MT-ND3/MT-CO1/MT-ND5/COL1A1/COL3A1/COX4I1/SLC25A6/MT-ND4L/COL1A2/ATP5F1D/MT-ATP8	13.7425466882028
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	14/68	138/9376	13.9880647911338	MT-ND4/MT-CYB/MT-ND1/MT-CO3/MT-ATP6/MT-ND2/MT-CO2/MT-ND3/MT-CO1/MT-ND5/COX4I1/MT-ND4L/ATP5F1D/MT-ATP8	13.1373242141066
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	16/68	227/9376	9.71857994299041	MT-ND4/MT-CYB/MT-ND1/MT-CO3/MT-ATP6/MT-ND2/MT-CO2/MT-ND3/MT-CO1/MT-ND5/COX4I1/SLC25A6/MT-ND4L/HGF/ATP5F1D/MT-ATP8	11.3653751645863
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	17/68	268/9376	8.74626865671642	MT-ND4/MT-CYB/MT-ND1/MT-CO3/MT-ATP6/MT-ND2/MT-CO2/MT-ND3/MT-CO1/MT-ND5/COX4I1/SLC25A6/MT-ND4L/RPS27A/ATP5F1D/UBA52/MT-ATP8	10.9966486284359
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	17/68	308/9376	7.61038961038961	MT-ND4/MT-CYB/MT-ND1/MT-CO3/MT-ATP6/MT-ND2/MT-CO2/MT-ND3/MT-CO1/MT-ND5/COX4I1/SLC25A6/MT-ND4L/GPX3/AP2S1/ATP5F1D/MT-ATP8	10.0822756507471
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	16/68	275/9376	8.02224598930481	MT-ND4/MT-CYB/MT-ND1/MT-CO3/MT-ATP6/MT-ND2/MT-CO2/MT-ND3/MT-CO1/MT-ND5/COX4I1/SLC25A6/MT-ND4L/C7/ATP5F1D/MT-ATP8	10.1020551637256
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	14/68	235/9376	8.21426783479349	MT-ND4/MT-CYB/MT-ND1/MT-CO3/MT-ATP6/MT-ND2/MT-CO2/MT-ND3/MT-CO1/MT-ND5/COX4I1/MT-ND4L/ATP5F1D/MT-ATP8	9.57284981952032
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	18/68	480/9376	5.17058823529412	MT-ND4/MT-CYB/MT-ND1/MT-CO3/MT-ATP6/MT-ND2/MT-CO2/MT-ND3/MT-CO1/MT-ND5/COX4I1/SLC25A6/MT-ND4L/GPX3/RPS27A/ATP5F1D/UBA52/MT-ATP8	8.01737970952935
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	15/68	368/9376	5.62020460358056	MT-ND4/MT-CYB/MT-ND1/MT-CO3/MT-ATP6/MT-ND2/MT-CO2/MT-ND3/MT-CO1/MT-ND5/COX4I1/MT-ND4L/GPX3/ATP5F1D/MT-ATP8	7.72827978480922
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	15/68	388/9376	5.33050333535476	MT-ND4/MT-CYB/MT-ND1/MT-CO3/MT-ATP6/MT-ND2/MT-CO2/MT-ND3/MT-CO1/MT-ND5/COX4I1/SLC25A6/MT-ND4L/ATP5F1D/MT-ATP8	7.44619860604106
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	10/68	233/9376	5.91769755112345	COL1A1/COL3A1/COL6A1/COL6A2/FBLN1/DCN/TLN1/MYL9/COL1A2/COL4A2	6.49691706731959
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	6/68	103/9376	8.03198172472873	COL1A1/COL3A1/COL6A1/COL6A2/COL1A2/COL4A2	6.13335529114243
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	8/68	203/9376	5.43378730802666	COL1A1/COL6A1/COL6A2/HGF/TLN1/MYL9/COL1A2/COL4A2	5.45857253001654
NA	NA	hsa04518	Integrin signaling	7/68	154/9376	6.26737967914439	COL1A1/COL6A1/COL6A2/HGF/TLN1/COL1A2/COL4A2	5.63318913128906
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	5/68	87/9376	7.92427315753888	MT-CYB/MT-CO3/MT-CO2/MT-CO1/COX4I1	5.54576221258809
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	5/68	89/9376	7.74619960343688	COL1A1/COL6A1/COL6A2/COL1A2/COL4A2	5.46548081961413
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	4/68	50/9376	11.0305882352941	HBB/HBA2/HBA1/HGF	6.07820868060416
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	6/68	149/9376	5.55230951440979	MT-ND4/MT-ND1/MT-ND2/MT-ND3/MT-ND5/MT-ND4L	4.78747548922322
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	3/68	37/9376	11.1796502384738	HBB/HBA2/HBA1	5.30268022403598
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	6/68	204/9376	4.05536332179931	COL1A1/DCN/HGF/LUM/COL1A2/GPC3	3.77101125624359
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	5/68	157/9376	4.39115773698014	MT-CYB/MT-CO3/MT-CO2/MT-CO1/COX4I1	3.66241721799958
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/68	101/9376	5.46068724519511	COL1A1/COL3A1/COL1A2/COL4A2	3.85227612724758
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	4/68	103/9376	5.35465448315248	COL1A1/COL3A1/COL1A2/COL4A2	3.79816731056291
Organismal Systems	Immune system	hsa04611	Platelet activation	4/68	126/9376	4.37721755368814	COL1A1/COL3A1/TLN1/COL1A2	3.26201047535668
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	4/68	130/9376	4.24253393665158	COL1A1/COL3A1/COL1A2/COL4A2	3.18193401296477
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	7/68	362/9376	2.6662333441664	COL1A1/CSH1/COL6A1/COL6A2/HGF/COL1A2/COL4A2	2.76339671405706
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	3/68	88/9376	4.70053475935829	F13A1/SERPINE2/C7	2.98096329044414
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	2/68	51/9376	5.40715109573241	PLA2G2A/ENPP2	2.69730784346871
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	3/68	134/9376	3.08691834942932	CALD1/PLA2G2A/MYL9	2.07963339124528
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	2/68	63/9376	4.37721755368814	PTGDS/PLA2G2A	2.2987747514622
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	5/68	333/9376	2.07030559971736	COL1A1/COL6A1/COL6A2/COL1A2/COL4A2	1.69975198173993
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	4/68	253/9376	2.17995814926761	TLN1/RPS27A/MYL9/UBA52	1.62618493872889
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	1/68	26/9376	5.30316742081448	PLA2G2A	1.87793700149442
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/68	105/9376	2.62633053221289	RPS27A/UBA52	1.43235966094721
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	1/68	30/9376	4.59607843137255	PLA2G2A	1.68612124886079
Human Diseases	Immune disease	hsa05310	Asthma	1/68	32/9376	4.30882352941176	HLA-DRB5	1.60248542032542
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	3/68	224/9376	1.84663865546218	HLA-DRB5/SLC25A6/TLN1	1.09616518414402
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/68	122/9376	2.26036644165863	CSH1/IGFBP3	1.197633419136
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/68	39/9376	3.53544494720965	HLA-DRB5	1.35610936896128
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/68	43/9376	3.20656634746922	PLA2G2A	1.2395170144141
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/68	44/9376	3.13368983957219	HLA-DRB5	1.21250117902407
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/68	142/9376	1.94200497100249	RPS27A/UBA52	0.966750352101209
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/68	143/9376	1.92842451665981	HLA-DRB5/C7	0.956214023092763
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/68	45/9376	3.0640522875817	HLA-DRB5	1.18624600892971
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/68	50/9376	2.75764705882353	HLA-DRB5	1.06507667943029
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/68	154/9376	1.79067990832697	EEF2/MYL9	0.845591116879504
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	2/68	157/9376	1.75646309479206	SLC25A6/IGFBP3	0.816972750319429
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/68	52/9376	2.65158371040724	PLTP	1.02073507251452
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/68	53/9376	2.6015538290788	AP2S1	0.999340619076726
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/68	54/9376	2.55337690631808	HLA-DRB5	0.978432978090337
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	2/68	166/9376	1.66123316796598	SLC25A6/MYL9	0.734667395252003
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/68	169/9376	1.63174382178907	RPS27A/UBA52	0.708332536901683
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/68	59/9376	2.3369890329013	GPX3	0.880496654449341
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/68	173/9376	1.59401564093846	HLA-DRB5/SLC25A6	0.674012775302841
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/68	66/9376	2.0891265597148	HLA-DRB5	0.758904946446706
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/68	70/9376	1.96974789915966	HGF	0.696046494512176
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/68	70/9376	1.96974789915966	HLA-DRB5	0.696046494512176
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/68	73/9376	1.88879935535858	HGF	0.651576717959075
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/68	73/9376	1.88879935535858	HGF	0.651576717959075
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/68	196/9376	1.40696278511405	RPS27A/UBA52	0.49212258787299
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/68	75/9376	1.83843137254902	IGFBP3	0.623082045823882
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/68	75/9376	1.83843137254902	GPX3	0.623082045823882
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/68	76/9376	1.81424148606811	PLTP	0.609158705732838
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/68	78/9376	1.76772247360483	HLA-DRB5	0.581927246185065
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/68	79/9376	1.74534623976173	AP2S1	0.568606869502264
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/68	80/9376	1.72352941176471	HGF	0.555475659529831
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/68	82/9376	1.68149210903874	HLA-DRB5	0.529758984484561
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	2/68	212/9376	1.3007769145394	HGF/TLN1	0.378601035405729
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/68	93/9376	1.48260594560405	MYL9	0.39976233608198
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/68	93/9376	1.48260594560405	HLA-DRB5	0.39976233608198
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/68	93/9376	1.48260594560405	COL4A2	0.39976233608198
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/68	95/9376	1.45139318885449	HLA-DRB5	0.377947367925565
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	2/68	232/9376	1.18864097363083	C7/MYL9	0.248670243874086
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/68	99/9376	1.39275103980986	HLA-DRB5	0.335770911589811
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	2/68	238/9376	1.1586752347998	HGF/PLA2G2A	0.211925862116963
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/68	100/9376	1.37882352941176	CXCL14	0.325513109124221
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/68	100/9376	1.37882352941176	HLA-DRB5	0.325513109124221
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/68	102/9376	1.3517877739331	PLA2G2A	0.305322766773964
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/68	104/9376	1.32579185520362	PLA2G2A	0.285549949807947
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	2/68	250/9376	1.10305882352941	DAB2/AP2S1	0.141164943879156
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/68	109/9376	1.26497571505666	HLA-DRB5	0.237827268270624
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/68	110/9376	1.25347593582888	DCN	0.228559268291528
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/68	254/9376	1.08568781843446	SLC25A6/HGF	0.118332166975702
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/68	112/9376	1.23109243697479	HLA-DRB5	0.210284556003027
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/68	116/9376	1.18864097363083	MYL9	0.174731593592235
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/68	122/9376	1.13018322082932	EEF2	0.123703528372884
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/68	298/9376	0.925384919068298	CSH1/CXCL14	-0.111879769890723
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/68	144/9376	0.957516339869281	SLC25A6	-0.043910378555362
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/68	150/9376	0.91921568627451	HGF	-0.0852467541033519
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/68	155/9376	0.889563567362429	HLA-DRB5	-0.11849529725365
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	1/68	160/9376	0.861764705882353	HLA-DRB5	-0.150736909350979
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/68	168/9376	0.820728291316526	SLC25A6	-0.200399046428628
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/68	168/9376	0.820728291316526	CSH1	-0.200399046428628
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/68	170/9376	0.811072664359862	MYL9	-0.212469053198782
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/68	170/9376	0.811072664359862	HGF	-0.212469053198782
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/68	180/9376	0.766013071895425	HLA-DRB5	-0.270919505557767
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/68	181/9376	0.761780955476113	HLA-DRB5	-0.276599764676028
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/68	184/9376	0.749360613810742	MYL9	-0.293470957626659
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/68	193/9376	0.71441633648278	CXCL14	-0.342634926016909
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/68	194/9376	0.710733778047301	MYL9	-0.347970038649842
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/68	195/9376	0.707088989441931	SLC25A6	-0.353280703385107
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/68	201/9376	0.685981855428739	IGFBP3	-0.38464637390501
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/68	205/9376	0.672596843615495	HLA-DRB5	-0.405101035245288
NA	NA	hsa04382	Cornified envelope formation	1/68	217/9376	0.635402548116021	COL4A2	-0.464441879373081
NA	NA	hsa04081	Hormone signaling	1/68	219/9376	0.629599785119527	CSH1	-0.474054842772299
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/68	226/9376	0.610098906819365	MYL9	-0.507119175450182
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/68	248/9376	0.555977229601518	MYL9	-0.605696653467912
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/68	250/9376	0.551529411764706	AP2S1	-0.614293111949023
NA	NA	hsa04517	IgSF CAM signaling	1/68	299/9376	0.461144993114303	MYL9	-0.809372149498536
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	1/68	300/9376	0.459607843137255	HGF	-0.813081965124865
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/68	370/9376	0.372655007949126	CSH1	-1.05233310620297