category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	35/64	238/9376	21.5441176470588	RPL13A/RPS11/RPS2/RPS8/RPS14/RPS20/RPL7/RPS16/RPL10/RPL27A/RPL18A/RPS9/RPS5/RPL23/RPL13/RPLP0/F13A1/RPL3/RPL15/RPSA/RPS4Y1/RPL21/RPS27A/RPS15/RPL18/RPL8/UBA52/RPLP2/RPS6/C1QA/RPL10A/RPL5/RPS12/RPS3/C1QB	26.6136558525183
Genetic Information Processing	Translation	hsa03010	Ribosome	33/64	222/9376	21.777027027027	RPL13A/RPS11/RPS2/RPS8/RPS14/RPS20/RPL7/RPS16/RPL10/RPL27A/RPL18A/RPS9/RPS5/RPL23/RPL13/RPLP0/RPL3/RPL15/RPSA/RPS4Y1/RPL21/RPS27A/RPS15/RPL18/RPL8/UBA52/RPLP2/RPS6/RPL10A/RPL5/RPS12/RPS3/RACK1	25.9721904864406
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	9/64	138/9376	9.55434782608696	MT-ND4/MT-ATP6/MT-CYB/MT-CO2/MT-ND1/MT-CO3/COX4I1/MT-ND2/MT-ND3	8.39250504131894
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	10/64	205/9376	7.14634146341463	MT-ND4/MT-ATP6/MT-CYB/MT-CO2/MT-ND1/MT-CO3/COX4I1/COL1A1/MT-ND2/MT-ND3	7.37631423134533
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	11/64	268/9376	6.01305970149254	MT-ND4/MT-ATP6/MT-CYB/MT-CO2/MT-ND1/MT-CO3/COX4I1/RPS27A/UBA52/MT-ND2/MT-ND3	6.90260313447191
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	11/64	275/9376	5.86	MT-ND4/MT-ATP6/MT-CYB/MT-CO2/MT-ND1/MT-CO3/COX4I1/C1QA/MT-ND2/MT-ND3/C1QB	6.78128817739086
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	10/64	235/9376	6.23404255319149	MT-ND4/MT-ATP6/MT-CYB/MT-CO2/MT-ND1/MT-CO3/COX4I1/RPS6/MT-ND2/MT-ND3	6.73640930958489
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	9/64	227/9376	5.80837004405286	MT-ND4/MT-ATP6/MT-CYB/MT-CO2/MT-ND1/MT-CO3/COX4I1/MT-ND2/MT-ND3	6.0796438564647
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	9/64	308/9376	4.28084415584416	MT-ND4/MT-ATP6/MT-CYB/MT-CO2/MT-ND1/MT-CO3/COX4I1/MT-ND2/MT-ND3	4.85354818329522
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	10/64	388/9376	3.77577319587629	MT-ND4/MT-ATP6/MT-CYB/MT-CO2/MT-ND1/MT-CO3/COX4I1/APOE/MT-ND2/MT-ND3	4.629375939857
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	11/64	480/9376	3.35729166666667	MT-ND4/MT-ATP6/MT-CYB/MT-CO2/MT-ND1/MT-CO3/COX4I1/RPS27A/UBA52/MT-ND2/MT-ND3	4.3953219712706
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	5/64	99/9376	7.3989898989899	HLA-DRA/HLA-DRB1/HLA-DRB5/C1QA/C1QB	5.30614831679229
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	9/64	368/9376	3.58288043478261	MT-ND4/MT-ATP6/MT-CYB/MT-CO2/MT-ND1/MT-CO3/COX4I1/MT-ND2/MT-ND3	4.19052238240443
Human Diseases	Immune disease	hsa05310	Asthma	3/64	32/9376	13.734375	HLA-DRA/HLA-DRB1/HLA-DRB5	5.9819165555872
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	4/64	78/9376	7.51282051282051	HLA-DRA/EEF1A1/HLA-DRB1/HLA-DRB5	4.78823858013945
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	4/64	82/9376	7.14634146341463	CD74/HLA-DRA/HLA-DRB1/HLA-DRB5	4.63421755157359
Human Diseases	Immune disease	hsa05330	Allograft rejection	3/64	39/9376	11.2692307692308	HLA-DRA/HLA-DRB1/HLA-DRB5	5.327465905838
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	5/64	143/9376	5.12237762237762	HLA-DRA/HLA-DRB1/HLA-DRB5/C1QA/C1QB	4.11811541873516
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	4/64	87/9376	6.73563218390805	MT-CYB/MT-CO2/MT-CO3/COX4I1	4.45564497886342
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	4/64	88/9376	6.65909090909091	F13A1/C1QA/SERPINE2/C1QB	4.42161622143563
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	3/64	44/9376	9.98863636363636	HLA-DRA/HLA-DRB1/HLA-DRB5	4.95435276076306
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	3/64	45/9376	9.76666666666667	HLA-DRA/HLA-DRB1/HLA-DRB5	4.88687012779122
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	3/64	50/9376	8.79	HLA-DRA/HLA-DRB1/HLA-DRB5	4.57855985265151
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	3/64	54/9376	8.13888888888889	HLA-DRA/HLA-DRB1/HLA-DRB5	4.36141180472047
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	3/64	66/9376	6.65909090909091	HLA-DRA/HLA-DRB1/HLA-DRB5	3.82470496334542
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	3/64	70/9376	6.27857142857143	HLA-DRA/HLA-DRB1/HLA-DRB5	3.67483665947185
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	4/64	149/9376	3.93288590604027	MT-ND4/MT-ND1/MT-ND2/MT-ND3	2.99165965044137
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	4/64	157/9376	3.73248407643312	MT-CYB/MT-CO2/MT-CO3/COX4I1	2.86232998425033
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	3/64	89/9376	4.93820224719101	SPP1/FN1/COL1A1	3.09463503342426
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/64	93/9376	4.7258064516129	HLA-DRA/HLA-DRB1/HLA-DRB5	2.99344808742347
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	2/64	37/9376	7.91891891891892	HBB/HBA2	3.49577165895559
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/64	95/9376	4.62631578947368	HLA-DRA/HLA-DRB1/HLA-DRB5	2.94499240298687
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	3/64	100/9376	4.395	HLA-DRA/HLA-DRB1/HLA-DRB5	2.82952509588077
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	4/64	180/9376	3.25555555555556	CD74/HLA-DRA/HLA-DRB1/HLA-DRB5	2.53305395932364
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	4/64	181/9376	3.23756906077348	CD74/HLA-DRA/HLA-DRB1/HLA-DRB5	2.51996210841731
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	3/64	109/9376	4.03211009174312	HLA-DRA/HLA-DRB1/HLA-DRB5	2.63962829394545
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/64	112/9376	3.92410714285714	HLA-DRA/HLA-DRB1/HLA-DRB5	2.5808167062076
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	2/64	50/9376	5.86	HBB/HBA2	2.85645710961314
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	2/64	52/9376	5.63461538461539	APOE/PLTP	2.77823117228593
NA	NA	hsa04518	Integrin signaling	3/64	154/9376	2.8538961038961	SPP1/FN1/COL1A1	1.92303564700604
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	3/64	155/9376	2.83548387096774	HLA-DRA/HLA-DRB1/HLA-DRB5	1.91021192605044
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	3/64	160/9376	2.746875	HLA-DRA/HLA-DRB1/HLA-DRB5	1.8475862835602
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	2/64	78/9376	3.75641025641026	C1QA/C1QB	2.02651829671256
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	5/64	362/9376	2.02348066298343	SPP1/FN1/CSH1/COL1A1/RPS6	1.64637700524385
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	3/64	173/9376	2.54046242774566	HLA-DRA/HLA-DRB1/HLA-DRB5	1.69536648033882
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/64	101/9376	2.9009900990099	FN1/COL1A1	1.59234703740015
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/64	103/9376	2.84466019417476	C1QA/C1QB	1.56055471525763
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/64	103/9376	2.84466019417476	FN1/COL1A1	1.56055471525763
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/64	105/9376	2.79047619047619	RPS27A/UBA52	1.52951609264612
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/64	203/9376	2.16502463054187	SPP1/FN1/COL1A1	1.39117437949586
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	3/64	204/9376	2.15441176470588	FN1/COL1A1/RPS6	1.38196787068877
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	3/64	205/9376	2.14390243902439	HLA-DRA/HLA-DRB1/HLA-DRB5	1.37281403750038
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	3/64	224/9376	1.96205357142857	HLA-DRA/HLA-DRB1/HLA-DRB5	1.20814594657982
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	3/64	233/9376	1.8862660944206	FN1/COL1A1/FBLN1	1.13566927715717
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/64	140/9376	2.09285714285714	SPP1/RPS6	1.08003938381231
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/64	142/9376	2.06338028169014	RPS27A/UBA52	1.05850272775968
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	2/64	144/9376	2.03472222222222	C1QA/C1QB	1.03731645216634
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/64	157/9376	1.86624203821656	C1QA/C1QB	0.907405309692411
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/64	56/9376	2.61607142857143	EEF1A1	1.00554324082979
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/64	169/9376	1.73372781065089	RPS27A/UBA52	0.797945817755563
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/64	59/9376	2.48305084745763	GSTP1	0.947323129464126
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/64	65/9376	2.25384615384615	SPP1	0.840924312125603
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/64	70/9376	2.09285714285714	GSTP1	0.760825451825701
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/64	196/9376	1.49489795918367	RPS27A/UBA52	0.58046561628423
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/64	73/9376	2.00684931506849	GSTP1	0.715926668096605
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/64	333/9376	1.31981981981982	SPP1/FN1/COL1A1	0.492635117325551
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/64	75/9376	1.95333333333333	GSTP1	0.687170851818105
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/64	76/9376	1.92763157894737	PLTP	0.673123864633885
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/64	78/9376	1.87820512820513	FN1	0.645658154999119
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/64	79/9376	1.85443037974684	GSTP1	0.632226875223287
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/64	80/9376	1.83125	RPS6	0.618988721421421
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/64	82/9376	1.78658536585366	GSTP1	0.593069508088287
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/64	93/9376	1.5752688172043	CST3	0.462191840338111
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/64	93/9376	1.5752688172043	FN1	0.462191840338111
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/64	98/9376	1.49489795918367	MARCKS	0.408277698741442
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/64	103/9376	1.42233009708738	COL1A1	0.3572848953353
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	2/64	248/9376	1.18145161290323	AHNAK/RPS3	0.240078350867438
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/64	106/9376	1.38207547169811	GSTP1	0.327956592232637
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/64	253/9376	1.15810276679842	RPS27A/UBA52	0.211341621334891
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/64	108/9376	1.35648148148148	EEF1A1	0.308894361429979
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/64	109/9376	1.34403669724771	SPP1	0.299503966786549
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/64	110/9376	1.33181818181818	RPS6	0.290204749263293
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/64	122/9376	1.20081967213115	CSH1	0.185086849476219
Organismal Systems	Immune system	hsa04611	Platelet activation	1/64	126/9376	1.16269841269841	COL1A1	0.152423476781477
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/64	130/9376	1.12692307692308	COL1A1	0.120806267145719
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/64	136/9376	1.07720588235294	RACK1	0.0751861766618986
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/64	138/9376	1.06159420289855	RPS6	0.0604288800094968
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/64	138/9376	1.06159420289855	FN1	0.0604288800094968
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/64	142/9376	1.03169014084507	GSTP1	0.0315447832776065
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/64	158/9376	0.927215189873418	RPS6	-0.0764900749585073
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/64	168/9376	0.872023809523809	CSH1	-0.138757128977797
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/64	170/9376	0.861764705882353	GSTP1	-0.150786360147396
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/64	200/9376	0.7325	RPS3	-0.317005081056748
NA	NA	hsa04081	Hormone signaling	1/64	219/9376	0.668949771689498	CSH1	-0.41095425701187
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	1/64	232/9376	0.631465517241379	FN1	-0.471203117531018
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/64	298/9376	0.491610738255034	CSH1	-0.739372941990655
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/64	323/9376	0.453560371517028	MARCKS	-0.828516820587652
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/64	370/9376	0.395945945945946	CSH1	-0.982799293615088