category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Genetic Information Processing	Translation	hsa03010	Ribosome	71/133	222/9376	22.5460949671476	RPS12/RPL13/RPS14/RPLP1/RPL10/RPS8/RPS18/RPS2/RPS23/RPL18A/RPS24/RPS3/RPL3/RPL18/RPL13A/RPS19/RPS4X/RPL32/RPS13/RPL19/RPL23A/RPS27A/RPL15/RPL8/RPL7A/RPS11/RPS6/RPL11/RPLP0/RPS15/RPL29/RPL10A/RPS16/RPL37A/RPS3A/RPLP2/RPS5/RPS28/RPL27A/RPL23/RPL26/RPL22/RPL7/RPL35/RPSA/RPS20/RPL5/RPL6/RPL21/RPL34/RPL9/RPL12/RPL35A/RACK1/RPS27/RPS9/RPS7/RPL14/RPL24/RPS25/RPL36/UBA52/RPL31/RPL27/RPS29/RPS15A/RPL28/RPS26/RPS4Y1/RPL41/RPL4	38.9712723517208
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	71/133	238/9376	21.0303911038099	RPS12/RPL13/RPS14/RPLP1/RPL10/RPS8/RPS18/RPS2/RPS23/RPL18A/RPS24/RPS3/RPL3/RPL18/RPL13A/RPS19/RPS4X/RPL32/RPS13/RPL19/RPL23A/RPS27A/RPL15/RPL8/RPL7A/RPS11/RPS6/RPL11/RPLP0/RPS15/RPL29/RPL10A/RPS16/RPL37A/RPS3A/RPLP2/RPS5/RPS28/RPL27A/RPL23/RPL26/RPL22/RPL7/RPL35/RPSA/RPS20/RPL5/RPL6/RPL21/RPL34/RPL9/RPL12/RPL35A/RPS27/RPS9/RPS7/RPL14/RPL24/RPS25/RPL36/UBA52/RPL31/RPL27/RPS29/RPS15A/RPL28/RPS26/RPS4Y1/C1QA/RPL41/RPL4	37.5454499235344
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	21/133	268/9376	5.52395915161037	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/RPS27A/UBA52/DUSP1/SLC25A6/GNAS/COX7C/COX4I1/ATP5PF/MT-ND6/SLC25A5/COX6C	9.013211104385
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	19/133	227/9376	5.90056639395846	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/CYBA/MGST3/SLC25A6/COX7C/COX4I1/ATP5PF/MT-ND6/SLC25A5/COX6C	8.96555903253138
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	18/133	205/9376	6.18991380891253	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/CYBA/SLC25A6/COX7C/COX4I1/ATP5PF/MT-ND6/SLC25A5/COX6C	9.01225997752326
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	15/133	138/9376	7.66263484798954	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/COX7C/COX4I1/ATP5PF/MT-ND6/COX6C	9.45804897265687
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	18/133	235/9376	5.39971204607263	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/RPS6/GNAS/COX7C/COX4I1/ACTG1/ATP5PF/MT-ND6/COX6C	8.19344065344146
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	19/133	275/9376	4.87064935064935	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/CYBA/SLC25A6/COX7C/COX4I1/C1QA/ATP5PF/MT-ND6/SLC25A5/COX6C	7.81466924807164
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	17/133	308/9376	3.89102626696612	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/SLC25A6/COX7C/COX4I1/ATP5PF/MT-ND6/SLC25A5/COX6C	6.18837498946346
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	18/133	388/9376	3.27044415161615	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/APOE/SLC25A6/COX7C/COX4I1/ATP5PF/MT-ND6/SLC25A5/COX6C	5.47898531826965
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	17/133	368/9376	3.25661981039555	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/PFN1/COX7C/COX4I1/ACTG1/ATP5PF/MT-ND6/COX6C	5.2975260276603
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	19/133	480/9376	2.79047619047619	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/RPS27A/UBA52/SLC25A6/COX7C/COX4I1/ATP5PF/MT-ND6/SLC25A5/COX6C	4.83055202621712
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	7/133	87/9376	5.67211131276467	MT-CO1/MT-CO3/MT-CYB/MT-CO2/COX7C/COX4I1/COX6C	5.25162017774546
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	7/133	142/9376	3.47516679021497	GSTP1/CYBA/CTSL/MGST3/DUSP1/ACTG1/HSP90AB1	3.56499305907509
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	7/133	157/9376	3.14314448541736	MT-CO1/MT-CO3/MT-CYB/MT-CO2/COX7C/COX4I1/COX6C	3.24836148069634
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	6/133	149/9376	2.8387747893223	MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/MT-ND6	2.71391597077938
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	3/133	52/9376	4.06709080393291	CGA/HSD17B1/GNAS	2.66030943922785
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	3/133	59/9376	3.58455460685612	GSTP1/MGST3/GPX4	2.38879374218663
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	3/133	82/9376	2.57913075371355	CTSL/CD74/HSP90AB1	1.72277541630134
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	6/133	248/9376	1.7055542081009	RPS3/PFN1/S100A10/ANXA2/ACTG1/HSP90AB1	1.35074507687046
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/133	51/9376	2.76455845496093	GNAS/ACTG1	1.5156596881843
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	5/133	204/9376	1.72784903435058	RPS6/FN1/CTSL/ACTG1/TIMP3	1.26075109202315
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	2/133	52/9376	2.71139386928861	APOE/PLTP	1.48441554415901
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	4/133	154/9376	1.83107118445464	RGS2/GNAS/ACTG1/EEF2	1.24735768767836
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	4/133	155/9376	1.81925782197429	CYBA/CTSL/CORO1A/ACTG1	1.23367969503126
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	3/133	103/9376	2.05328856120885	FN1/PRDX1/GNAS	1.28932033503053
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	3/133	106/9376	1.99517662079728	GSTP1/FOLR3/HSP90AB1	1.23599926507593
NA	NA	hsa04382	Cornified envelope formation	5/133	217/9376	1.62433734104847	KRT18/S100A10/S100A9/KRT7/KRT8	1.11616944618327
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/133	59/9376	2.38970307123742	CGA/GNAS	1.28444335873701
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	4/133	168/9376	1.67848191908342	SLC25A6/PPIA/HSP90AB1/SLC25A5	1.06442544143161
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	4/133	169/9376	1.66855007340837	RPS27A/CTSL/UBA52/VAMP8	1.05201808012275
Organismal Systems	Digestive system	hsa04980	Cobalamin transport and metabolism	1/133	18/9376	3.91645781119465	PRDX1	1.48561204770552
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/133	65/9376	2.16911509543089	CGA/SPP1	1.13454248965951
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	2/133	70/9376	2.01417830290011	GSTP1/MGST3	1.02161389979935
Organismal Systems	Immune system	hsa04611	Platelet activation	3/133	126/9376	1.67848191908342	VAMP8/GNAS/ACTG1	0.919724312374837
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	2/133	73/9376	1.93140385209599	GSTP1/MGST3	0.958281119366941
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/133	75/9376	1.87989974937343	GSTP1/MGST3	0.91770687592599
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	2/133	75/9376	1.87989974937343	CGA/GNAS	0.91770687592599
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	2/133	76/9376	1.85516422635536	GNAS/ACTG1	0.897883165470539
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	4/133	195/9376	1.44607673028726	CYBA/SLC25A6/ACTG1/SLC25A5	0.755069386996912
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/133	78/9376	1.80759591285907	FN1/ACTG1	0.859115639242636
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/133	78/9376	1.80759591285907	EEF1A1/CYBA	0.859115639242636
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	2/133	79/9376	1.7847149519368	GSTP1/MGST3	0.840154272061439
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/133	139/9376	1.52150159571591	KRT18/GNAS/HSP90AB1	0.74302350424292
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	2/133	82/9376	1.7194205024757	GSTP1/MGST3	0.784862148199997
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	2/133	83/9376	1.69870459280732	PRDX1/PRDX5	0.766936942573493
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/133	30/9376	2.34987468671679	FOLR3	0.88827241319952
NA	NA	hsa04981	Folate transport and metabolism	1/133	31/9376	2.27407227746786	FOLR3	0.852295591827571
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/133	89/9376	1.58418518205626	FN1/SPP1	0.664221301939848
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/133	32/9376	2.20300751879699	LDHB	0.817677218860035
NA	NA	hsa04518	Integrin signaling	3/133	154/9376	1.37330338834098	FN1/SPP1/ACTG1	0.560292379273219
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/133	33/9376	2.13624971519708	VAMP8	0.784318691547356
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/133	93/9376	1.51604818497858	CGA/GNAS	0.599918888735921
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/133	94/9376	1.49992001279795	S100A9/HSP90AB1	0.58431717212389
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/133	37/9376	1.90530380004064	HBB	0.661835410687756
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/133	99/9376	1.42416647679806	KRT18/C1QA	0.508926591062062
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/133	232/9376	1.21545242416386	FN1/TMSB4X/PFN1/ACTG1	0.398595371023012
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/133	166/9376	1.27402844460549	RGS2/SLC25A6/SLC25A5	0.427292093412289
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/133	103/9376	1.3688590408059	GNAS/C1QA	0.451516782376414
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/133	170/9376	1.24405130473242	GSTP1/MGST3/ACTG1	0.385190077683075
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/133	105/9376	1.34278553526674	RPS27A/UBA52	0.423700355711519
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/133	105/9376	1.34278553526674	GNAS/ACTG1	0.423700355711519
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	3/133	173/9376	1.22247816071972	SLC25A6/ACTG1/SLC25A5	0.354283321924141
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	2/133	107/9376	1.31768674021502	LDHB/GNAS	0.396441872091389
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/133	42/9376	1.67848191908342	GPX4	0.528608336176481
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/133	110/9376	1.28174982911825	RPS6/LDHB	0.356548684243706
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/133	44/9376	1.60218728639781	GNAS	0.48025902808167
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	4/133	253/9376	1.11456506879848	RPS27A/PFN1/UBA52/ACTG1	0.2215892183688
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/133	115/9376	1.22602157567833	DUSP1/GNAS	0.292532995609684
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/133	47/9376	1.49992001279795	LDHB	0.412132522628018
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/133	116/9376	1.21545242416386	CYBA/ACTG1	0.280078562244886
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/133	49/9376	1.43869878778579	GNAS	0.369316293396521
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/133	50/9376	1.40992481203008	HBB	0.348615333309693
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/133	122/9376	1.15567607543449	CSH1/GNAS	0.207607015166824
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/133	53/9376	1.33011774719818	GNAS	0.289090584748497
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/133	54/9376	1.30548593706488	LDHB	0.270046489023372
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/133	54/9376	1.30548593706488	CGA	0.270046489023372
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/133	200/9376	1.05744360902256	RPS3/ACTG1/NCL	0.0984997198199044
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/133	56/9376	1.25886143931257	EEF1A1	0.233054987277342
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/133	203/9376	1.04181636356902	FN1/SPP1/ACTG1	0.0722509509274921
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/133	60/9376	1.1749373433584	GNAS	0.163060359080131
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/133	137/9376	1.0291421985621	CTSL/ACTG1	0.0412168782262333
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	3/133	212/9376	0.997588310398638	PFN1/GNAS/ACTG1	-0.00426041380424963
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/133	138/9376	1.02168464639861	FN1/ACTG1	0.0307827837292693
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	5/133	362/9376	0.973704980683753	RPS6/CSH1/FN1/SPP1/HSP90AB1	-0.0612031795637093
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/133	140/9376	1.00708915145005	RPS6/SPP1	0.0101372765036488
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/133	63/9376	1.11898794605562	GPX4	0.113666744931651
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/133	217/9376	0.974602404629084	MGST3/GNAS/HSP90AB1	-0.0454049727538896
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/133	142/9376	0.992904797204278	RPS27A/UBA52	-0.0102192502014303
NA	NA	hsa04081	Hormone signaling	3/133	219/9376	0.965701926047997	CSH1/CGA/GNAS	-0.0616055962017816
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/133	65/9376	1.08455754771544	GNAS	0.0820570456061249
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/133	144/9376	0.979114452798663	SLC25A6/SLC25A5	-0.0302959230181048
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/133	66/9376	1.06812485759854	HSD17B1	0.0666204737827727
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/133	67/9376	1.05218269554483	LDHB	0.051418260190236
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/133	69/9376	1.02168464639861	GNAS	0.0216858782538625
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/133	69/9376	1.02168464639861	GNAS	0.0216858782538625
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/133	70/9376	1.00708915145005	ACTG1	0.00714112660313043
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/133	71/9376	0.992904797204278	CGA	-0.0071984796427142
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/133	71/9376	0.992904797204278	LDHB	-0.0071984796427142
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	3/133	233/9376	0.907676917615928	FN1/FBLN1/ACTG1	-0.17117836684613
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/133	73/9376	0.965701926047997	PPIA	-0.035287804130177
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	2/133	157/9376	0.898041281547819	SLC25A6/SLC25A5	-0.154538705110556
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/133	76/9376	0.927582113177681	PLTP	-0.0760354554748305
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/133	78/9376	0.903797956429535	ISYNA1	-0.102339151105771
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/133	78/9376	0.903797956429535	C1QA	-0.102339151105771
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/133	80/9376	0.881203007518797	RPS6	-0.127999232074313
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	3/133	254/9376	0.832632763009887	SLC25A6/GNAS/SLC25A5	-0.324374908800836
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/133	86/9376	0.819723727924462	GNAS	-0.201458186201303
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/133	86/9376	0.819723727924462	ACTG1	-0.201458186201303
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/133	88/9376	0.801093643198906	C1QA	-0.224871220852406
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/133	89/9376	0.792092591028132	GNAS	-0.23639170268604
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/133	90/9376	0.783291562238931	GNAS	-0.247792249651974
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/133	91/9376	0.774683962653888	GNAS	-0.259075788698471
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/133	181/9376	0.778963984547003	CD74/CORO1A	-0.36018982966626
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/133	93/9376	0.758024092489288	ACTG1	-0.281303028981139
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/133	93/9376	0.758024092489288	GNAS	-0.281303028981139
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/133	93/9376	0.758024092489288	FN1	-0.281303028981139
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/133	95/9376	0.742065690542145	CTSL	-0.303094818954121
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/133	187/9376	0.753970487716618	CYBA/HSP90AB1	-0.407641945255583
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/133	97/9376	0.726765367025812	GNAS	-0.324471090230388
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/133	98/9376	0.719349393892895	GNAS	-0.335009266828753
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/133	99/9376	0.712083238399028	GNAS	-0.345450439877579
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/133	99/9376	0.712083238399028	GNAS	-0.345450439877579
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/133	99/9376	0.712083238399028	ACTG1	-0.345450439877579
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/133	101/9376	0.697982580212908	GNAS	-0.366050245844213
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/133	101/9376	0.697982580212908	FN1	-0.366050245844213
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/133	102/9376	0.691139613740233	GNAS	-0.376212942853044
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/133	196/9376	0.719349393892895	RPS27A/UBA52	-0.476296797817092
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/133	108/9376	0.652742968532442	EEF1A1	-0.435386436769533
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/133	109/9376	0.646754500931227	SPP1	-0.444964421023118
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/133	109/9376	0.646754500931227	HSP90AB1	-0.444964421023118
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/133	110/9376	0.640874914559125	HSP90AB1	-0.454465499033584
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/133	115/9376	0.613010787839163	GNAS	-0.500868614698791
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/133	116/9376	0.607726212081929	GNAS	-0.509938465314697
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/133	117/9376	0.602531970953024	ACTG1	-0.518941104988104
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/133	216/9376	0.652742968532442	CYBA/HSP90AB1	-0.619348612869167
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/133	120/9376	0.587468671679198	BEX3	-0.545557923127208
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/133	122/9376	0.577838037717244	EEF2	-0.562988144850651
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/133	122/9376	0.577838037717244	ACTG1	-0.562988144850651
NA	NA	hsa04519	Cadherin signaling	4/133	404/9376	0.697982580212908	KRT18/KRT7/KRT8/ACTG1	-0.744359996584031
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/133	224/9376	0.629430719656283	SLC25A6/SLC25A5	-0.673349279418858
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/133	226/9376	0.623860536296493	CGA/GNAS	-0.68659012957725
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/133	130/9376	0.542278773857721	GNAS	-0.630377591290852
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/133	133/9376	0.530046921815818	GNAS	-0.654755001692446
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/133	134/9376	0.526091347772416	GNAS	-0.662779454121003
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/133	333/9376	0.635101266680214	FN1/SPP1/GNAS	-0.813285799477877
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/133	136/9376	0.518354710305175	RACK1	-0.678681120440757
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/133	138/9376	0.510842323199303	RPS6	-0.694391538495931
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/133	142/9376	0.496452398602139	CYBA	-0.725261712056735
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/133	143/9376	0.492980703507019	C1QA	-0.732868527179782
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/133	144/9376	0.489557226399332	DUSP9	-0.740432358562485
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/133	144/9376	0.489557226399332	C1QA	-0.740432358562485
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/133	250/9376	0.56396992481203	CTSL/VAMP8	-0.838206839197781
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	2/133	250/9376	0.56396992481203	DAB2/FOLR3	-0.838206839197781
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/133	149/9376	0.473129131553716	GNAS	-0.777628273303536
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/133	154/9376	0.457767796113661	GNAS	-0.813838237537062
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/133	155/9376	0.454814455493573	GNAS	-0.820967854370084
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/133	157/9376	0.449020640773909	C1QA	-0.835118742271936
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/133	157/9376	0.449020640773909	ACTG1	-0.835118742271936
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/133	158/9376	0.446178737984201	CDKN1C	-0.842140974791393
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/133	158/9376	0.446178737984201	RPS6	-0.842140974791393
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/133	168/9376	0.419620479770856	CSH1	-0.910519071535957
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/133	170/9376	0.41468376824414	ACTG1	-0.923813970289565
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/133	174/9376	0.405150808054619	HSP90AB1	-0.950047605746835
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/133	180/9376	0.391645781119465	CD74	-0.988549174112264
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/133	300/9376	0.469974937343358	DUSP1/DUSP9	-1.11921822115441
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/133	191/9376	0.369090264929339	GNAS	-1.05669417691942
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/133	194/9376	0.363382683512906	ACTG1	-1.07477028464211
NA	NA	hsa04082	Neuroactive ligand signaling	1/133	199/9376	0.35425246533419	GNAS	-1.10444453690912
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/133	227/9376	0.310556125997814	GNAS	-1.26133374289227
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	2/133	370/9376	0.381060760008128	CSH1/CGA	-1.45709507471907
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/133	298/9376	0.236564565776858	CSH1	-1.60653554363721
NA	NA	hsa04517	IgSF CAM signaling	1/133	299/9376	0.23577337993814	ACTG1	-1.61098527142419
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/133	323/9376	0.218254614865337	TIMP3	-1.71504416909438
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/133	449/9376	0.157007217375287	RGS2	-2.19583266673644