ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 70/157 175/18639 0.4 47.487898089172 3.97249400053742e-104 1.43804282819455e-101 GO:0019843 rRNA binding 17/157 65/18639 0.261538461538462 31.0497795198432 2.94352991701109e-21 5.32778914979007e-19 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 11/157 68/18639 0.161764705882353 19.2046646684151 1.07883311107232e-11 1.25720960454271e-09 GO:0048027 mRNA 5'-UTR binding 8/157 24/18639 0.333333333333333 39.5732484076433 1.38918188347261e-11 1.25720960454271e-09 GO:1990948 ubiquitin ligase inhibitor activity 6/157 11/18639 0.545454545454545 64.7562246670527 1.44788625930372e-10 1.04826965173589e-08 GO:0009055 electron transfer activity 12/157 116/18639 0.103448275862069 12.2813529540962 2.70223016678866e-10 1.63034553396249e-08 GO:0045296 cadherin binding 18/157 334/18639 0.0538922155688623 6.39807010183455 4.59529944154763e-10 2.37642628262892e-08 GO:0015078 proton transmembrane transporter activity 14/157 185/18639 0.0756756756756757 8.98419693578929 5.5676336383807e-10 2.51935422136727e-08 GO:0055105 ubiquitin-protein transferase inhibitor activity 6/157 15/18639 0.4 47.487898089172 1.52544135264063e-09 6.13566410728788e-08 GO:0022853 active monoatomic ion transmembrane transporter activity 11/157 118/18639 0.0932203389830508 11.067094893663 4.69572902753536e-09 1.6998539079678e-07 GO:0016209 antioxidant activity 9/157 86/18639 0.104651162790698 12.424159383795 4.48346194254934e-08 1.47546656654806e-06 GO:0015399 primary active transmembrane transporter activity 11/157 166/18639 0.0662650602409639 7.86697106898933 1.63555035372122e-07 4.93391023372568e-06 GO:0004601 peroxidase activity 7/157 57/18639 0.12280701754386 14.5796178343949 4.88546512858339e-07 1.3263719503946e-05 GO:0055106 ubiquitin-protein transferase regulator activity 6/157 36/18639 0.166666666666667 19.7866242038217 5.12961527776918e-07 1.3263719503946e-05 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/157 59/18639 0.11864406779661 14.0853935010256 6.21575094788521e-07 1.50006789542296e-05 GO:0008137 NADH dehydrogenase (ubiquinone) activity 6/157 41/18639 0.146341463414634 17.3736212521361 1.1437196998623e-06 2.58766582093846e-05 GO:0003954 NADH dehydrogenase activity 6/157 44/18639 0.136363636363636 16.1890561667632 1.75854806302549e-06 3.74467293420721e-05 GO:0004129 cytochrome-c oxidase activity 4/157 15/18639 0.266666666666667 31.6585987261146 6.15196126003531e-06 0.000123722776451821 GO:0016675 oxidoreductase activity, acting on a heme group of donors 4/157 16/18639 0.25 29.6799363057325 8.1488760380518e-06 0.000155257532935513 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 6/157 58/18639 0.103448275862069 12.2813529540962 9.14984652631238e-06 0.000162584674048473 GO:0016651 oxidoreductase activity, acting on NAD(P)H 7/157 88/18639 0.0795454545454545 9.44361609727852 9.43170761054678e-06 0.000162584674048473 GO:0004857 enzyme inhibitor activity 14/157 416/18639 0.0336538461538462 3.9953760411563 1.17862177283228e-05 0.000193936855347857 GO:0022804 active transmembrane transporter activity 13/157 457/18639 0.0284463894967177 3.37714811356256 0.00013482360245508 0.00212200626472778 GO:0003746 translation elongation factor activity 3/157 18/18639 0.166666666666667 19.7866242038217 0.000435968520102713 0.00657585851154926 GO:0061134 peptidase regulator activity 8/157 226/18639 0.0353982300884956 4.20246885744885 0.000671389626859897 0.00972172179693131 GO:0004602 glutathione peroxidase activity 3/157 23/18639 0.130434782608696 15.4851841595126 0.000917425138494712 0.0127733807744264 GO:0016504 peptidase activator activity 4/157 57/18639 0.0701754385964912 8.3312101910828 0.00135267416302495 0.0181358535931493 GO:0003785 actin monomer binding 3/157 29/18639 0.103448275862069 12.2813529540962 0.0018241460770147 0.0235836028528329 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/157 10/18639 0.2 23.743949044586 0.00303488501791012 0.0378837371201195 GO:0010854 adenylate cyclase regulator activity 2/157 11/18639 0.181818181818182 21.5854082223509 0.0036888461600819 0.0417748737838777 GO:0015217 ADP transmembrane transporter activity 2/157 11/18639 0.181818181818182 21.5854082223509 0.0036888461600819 0.0417748737838777 GO:0043394 proteoglycan binding 3/157 37/18639 0.0810810810810811 9.62592528834567 0.00369280652233173 0.0417748737838777 GO:0031625 ubiquitin protein ligase binding 8/157 302/18639 0.0264900662251656 3.1448939131902 0.00413098640822815 0.0453156690841997 GO:0097371 MDM2/MDM4 family protein binding 2/157 12/18639 0.166666666666667 19.7866242038217 0.00440221778329819 0.0468706716927631 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/157 40/18639 0.075 8.90398089171974 0.00461000872342192 0.0476806616536782 GO:0033218 amide binding 7/157 247/18639 0.0283400809716599 3.36452719255267 0.00500333013246476 0.0503112641097845 GO:0005347 ATP transmembrane transporter activity 2/157 14/18639 0.142857142857143 16.9599636032757 0.00600306824271887 0.0574812658996237 GO:0044389 ubiquitin-like protein ligase binding 8/157 322/18639 0.0248447204968944 2.94955888752621 0.00603394503918702 0.0574812658996237 GO:0031386 protein tag activity 2/157 15/18639 0.133333333333333 15.8292993630573 0.00688851736012036 0.0623410821090893 GO:0141047 molecular tag activity 2/157 15/18639 0.133333333333333 15.8292993630573 0.00688851736012036 0.0623410821090893 GO:0008429 phosphatidylethanolamine binding 2/157 17/18639 0.117647058823529 13.9670288497565 0.00882448476463779 0.0742898484836949 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/157 17/18639 0.117647058823529 13.9670288497565 0.00882448476463779 0.0742898484836949 GO:0016018 cyclosporin A binding 2/157 17/18639 0.117647058823529 13.9670288497565 0.00882448476463779 0.0742898484836949 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/157 18/18639 0.111111111111111 13.1910828025478 0.00987304929520468 0.0794231965525354 GO:0098641 cadherin binding involved in cell-cell adhesion 2/157 18/18639 0.111111111111111 13.1910828025478 0.00987304929520468 0.0794231965525354 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/157 19/18639 0.105263157894737 12.4968152866242 0.0109740524863711 0.0846115218807957 GO:0019207 kinase regulator activity 7/157 287/18639 0.024390243902439 2.89560354202268 0.0109854738353519 0.0846115218807957 GO:0010851 cyclase regulator activity 2/157 20/18639 0.1 11.871974522293 0.012126548173723 0.0895879681405659 GO:0016505 peptidase activator activity involved in apoptotic process 2/157 20/18639 0.1 11.871974522293 0.012126548173723 0.0895879681405659 GO:0043022 ribosome binding 4/157 112/18639 0.0357142857142857 4.23999090081893 0.0149101273524545 0.107949322031771 GO:0000295 adenine nucleotide transmembrane transporter activity 2/157 23/18639 0.0869565217391304 10.3234561063417 0.0158837083861924 0.110575046842339 GO:0017134 fibroblast growth factor binding 2/157 23/18639 0.0869565217391304 10.3234561063417 0.0158837083861924 0.110575046842339 GO:0043021 ribonucleoprotein complex binding 5/157 177/18639 0.0282485875706215 3.35366511929181 0.0171187761310862 0.116924470933079 GO:0120020 cholesterol transfer activity 2/157 25/18639 0.08 9.4975796178344 0.0186291337381526 0.123149822932607 GO:0050840 extracellular matrix binding 3/157 67/18639 0.0447761194029851 5.31580948759388 0.0189605154471803 0.123149822932607 GO:0051082 unfolded protein binding 4/157 121/18639 0.0330578512396694 3.92461967679107 0.0192531560212222 0.123149822932607 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/157 26/18639 0.0769230769230769 9.13228809407154 0.0200713799807288 0.123149822932607 GO:0015216 purine nucleotide transmembrane transporter activity 2/157 26/18639 0.0769230769230769 9.13228809407154 0.0200713799807288 0.123149822932607 GO:0050750 low-density lipoprotein particle receptor binding 2/157 26/18639 0.0769230769230769 9.13228809407154 0.0200713799807288 0.123149822932607 GO:0004364 glutathione transferase activity 2/157 27/18639 0.0740740740740741 8.79405520169851 0.0215588253356577 0.123877694785843 GO:0015252 proton channel activity 2/157 27/18639 0.0740740740740741 8.79405520169851 0.0215588253356577 0.123877694785843 GO:0023026 MHC class II protein complex binding 2/157 27/18639 0.0740740740740741 8.79405520169851 0.0215588253356577 0.123877694785843 GO:0035255 ionotropic glutamate receptor binding 2/157 27/18639 0.0740740740740741 8.79405520169851 0.0215588253356577 0.123877694785843 GO:0005518 collagen binding 3/157 72/18639 0.0416666666666667 4.94665605095541 0.0229012685965558 0.128761418252469 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 4/157 128/18639 0.03125 3.70999203821656 0.0231201441613549 0.128761418252469 GO:0043236 laminin binding 2/157 29/18639 0.0689655172413793 8.18756863606413 0.0246659103941274 0.135288781252638 GO:0001968 fibronectin binding 2/157 30/18639 0.0666666666666667 7.91464968152866 0.0262838760058275 0.138241734099857 GO:0015215 nucleotide transmembrane transporter activity 2/157 30/18639 0.0666666666666667 7.91464968152866 0.0262838760058275 0.138241734099857 GO:0098631 cell adhesion mediator activity 3/157 76/18639 0.0394736842105263 4.68630573248408 0.0263499437925142 0.138241734099857 GO:0070325 lipoprotein particle receptor binding 2/157 31/18639 0.0645161290322581 7.65933840147935 0.0279436923015193 0.144508808759285 GO:1901681 sulfur compound binding 6/157 275/18639 0.0218181818181818 2.59024898668211 0.0291681336971066 0.145017929328963 GO:0071813 lipoprotein particle binding 2/157 32/18639 0.0625 7.41998407643312 0.0296445490893461 0.145017929328963 GO:0071814 protein-lipid complex binding 2/157 32/18639 0.0625 7.41998407643312 0.0296445490893461 0.145017929328963 GO:0120015 sterol transfer activity 2/157 32/18639 0.0625 7.41998407643312 0.0296445490893461 0.145017929328963 GO:0048306 calcium-dependent protein binding 3/157 80/18639 0.0375 4.45199044585987 0.0300611435094678 0.145095119339031 GO:0001540 amyloid-beta binding 3/157 83/18639 0.036144578313253 4.29107512853964 0.0330159151606757 0.153925165517901 GO:0008135 translation factor activity, RNA binding 3/157 83/18639 0.036144578313253 4.29107512853964 0.0330159151606757 0.153925165517901 GO:0051427 hormone receptor binding 2/157 34/18639 0.0588235294117647 6.98351442487823 0.0331661958850726 0.153925165517901 GO:0004860 protein kinase inhibitor activity 3/157 84/18639 0.0357142857142857 4.23999090081893 0.0340333026783639 0.154000694619597 GO:0180051 translation factor activity 3/157 84/18639 0.0357142857142857 4.23999090081893 0.0340333026783639 0.154000694619597 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/157 36/18639 0.0555555555555556 6.59554140127389 0.0368425432594807 0.16068675493894 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/157 36/18639 0.0555555555555556 6.59554140127389 0.0368425432594807 0.16068675493894 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/157 36/18639 0.0555555555555556 6.59554140127389 0.0368425432594807 0.16068675493894 GO:0023023 MHC protein complex binding 2/157 37/18639 0.0540540540540541 6.41728352556378 0.0387368139301748 0.166937221937182 GO:0019210 kinase inhibitor activity 3/157 90/18639 0.0333333333333333 3.95732484076433 0.0404754130265257 0.172377641360027 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/157 39/18639 0.0512820512820513 6.08819206271436 0.0426338052150456 0.179458575440076 GO:0004867 serine-type endopeptidase inhibitor activity 3/157 95/18639 0.0315789473684211 3.74904458598726 0.0462801998417258 0.192568187847181 GO:0004866 endopeptidase inhibitor activity 4/157 161/18639 0.0248447204968944 2.94955888752621 0.0473967380939154 0.192782238089858 GO:0005178 integrin binding 4/157 161/18639 0.0248447204968944 2.94955888752621 0.0473967380939154 0.192782238089858 GO:0016859 cis-trans isomerase activity 2/157 42/18639 0.0476190476190476 5.6533212010919 0.0487394780290429 0.196041011627928 GO:0008200 ion channel inhibitor activity 2/157 43/18639 0.0465116279069767 5.52184861502 0.0508412351519557 0.200049207880521 GO:0048156 tau protein binding 2/157 43/18639 0.0465116279069767 5.52184861502 0.0508412351519557 0.200049207880521 GO:0016248 channel inhibitor activity 2/157 44/18639 0.0454545454545455 5.39635205558772 0.0529750985960352 0.205781647258813 GO:0005201 extracellular matrix structural constituent 4/157 168/18639 0.0238095238095238 2.82666060054595 0.05385120655182 0.205781647258813 GO:0005539 glycosaminoglycan binding 5/157 242/18639 0.0206611570247934 2.45288729799442 0.0542113739008237 0.205781647258813 GO:0030414 peptidase inhibitor activity 4/157 169/18639 0.0236686390532544 2.80993479817586 0.0548104119969026 0.205781647258813 GO:0141110 transporter inhibitor activity 2/157 45/18639 0.0444444444444444 5.27643312101911 0.055140386143936 0.205781647258813 GO:0008201 heparin binding 4/157 172/18639 0.0232558139534884 2.76092430751 0.0577434404065764 0.212718269995241 GO:0042393 histone binding 5/157 247/18639 0.0202429149797571 2.40323370896619 0.0581743335069859 0.212718269995241 GO:0005504 fatty acid binding 2/157 47/18639 0.0425531914893617 5.05190405203957 0.0595625499990429 0.215616430996535 GO:0035254 glutamate receptor binding 2/157 49/18639 0.0408163265306122 4.8457038866502 0.0641024488127949 0.229753331388433 GO:0019887 protein kinase regulator activity 5/157 255/18639 0.0196078431372549 2.32783814162608 0.0648525183521611 0.230162859249827 GO:0015605 organophosphate ester transmembrane transporter activity 2/157 50/18639 0.04 4.7487898089172 0.0664149379784224 0.233419490759116 GO:0061135 endopeptidase regulator activity 4/157 184/18639 0.0217391304347826 2.58086402658543 0.070297855247319 0.244690611533937 GO:0005080 protein kinase C binding 2/157 52/18639 0.0384615384615385 4.56614404703577 0.071121849545026 0.245201043193328 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/157 53/18639 0.0377358490566038 4.47999038577094 0.0735150388211722 0.248886488117827 GO:0031406 carboxylic acid binding 4/157 187/18639 0.0213903743315508 2.53945979086481 0.073639004951918 0.248886488117827 GO:0043177 organic acid binding 4/157 189/18639 0.0211640211640212 2.51258720048529 0.0759107008666797 0.248886488117827 GO:0098632 cell-cell adhesion mediator activity 2/157 55/18639 0.0363636363636364 4.31708164447018 0.0783778638624953 0.248886488117827 GO:0005131 growth hormone receptor binding 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.248886488117827 GO:0005345 purine nucleobase transmembrane transporter activity 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.248886488117827 GO:0005522 profilin binding 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.248886488117827 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.248886488117827 GO:0030957 Tat protein binding 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.248886488117827 GO:0031720 haptoglobin binding 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.248886488117827 GO:0032356 oxidized DNA binding 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.248886488117827 GO:0070513 death domain binding 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.248886488117827 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.248886488117827 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/157 57/18639 0.0350877192982456 4.1656050955414 0.0833386853971224 0.253517681628221 GO:0008432 JUN kinase binding 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.257375439413591 GO:0008526 phosphatidylinositol transfer activity 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.257375439413591 GO:0015205 nucleobase transmembrane transporter activity 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.257375439413591 GO:0050786 RAGE receptor binding 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.257375439413591 GO:0050998 nitric-oxide synthase binding 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.257375439413591 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.257375439413591 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/157 61/18639 0.0327868852459016 3.89245066304688 0.0935360162545668 0.268730459398041 GO:0004859 phospholipase inhibitor activity 1/157 12/18639 0.0833333333333333 9.89331210191083 0.0965518724969446 0.270944014293752 GO:0005165 neurotrophin receptor binding 1/157 12/18639 0.0833333333333333 9.89331210191083 0.0965518724969446 0.270944014293752 GO:0010853 cyclase activator activity 1/157 12/18639 0.0833333333333333 9.89331210191083 0.0965518724969446 0.270944014293752 GO:0120013 lipid transfer activity 2/157 65/18639 0.0307692307692308 3.65291523762861 0.104071663094243 0.277267240460843 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/157 13/18639 0.0769230769230769 9.13228809407154 0.104166698073687 0.277267240460843 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/157 13/18639 0.0769230769230769 9.13228809407154 0.104166698073687 0.277267240460843 GO:0005542 folic acid binding 1/157 13/18639 0.0769230769230769 9.13228809407154 0.104166698073687 0.277267240460843 GO:0008035 high-density lipoprotein particle binding 1/157 13/18639 0.0769230769230769 9.13228809407154 0.104166698073687 0.277267240460843 GO:0035325 Toll-like receptor binding 1/157 13/18639 0.0769230769230769 9.13228809407154 0.104166698073687 0.277267240460843 GO:0043560 insulin receptor substrate binding 1/157 13/18639 0.0769230769230769 9.13228809407154 0.104166698073687 0.277267240460843 GO:0005344 oxygen carrier activity 1/157 14/18639 0.0714285714285714 8.47998180163785 0.111717746522223 0.284801579162287 GO:0008191 metalloendopeptidase inhibitor activity 1/157 14/18639 0.0714285714285714 8.47998180163785 0.111717746522223 0.284801579162287 GO:0019992 diacylglycerol binding 1/157 14/18639 0.0714285714285714 8.47998180163785 0.111717746522223 0.284801579162287 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/157 14/18639 0.0714285714285714 8.47998180163785 0.111717746522223 0.284801579162287 GO:0032036 myosin heavy chain binding 1/157 14/18639 0.0714285714285714 8.47998180163785 0.111717746522223 0.284801579162287 GO:0044548 S100 protein binding 1/157 14/18639 0.0714285714285714 8.47998180163785 0.111717746522223 0.284801579162287 GO:0097110 scaffold protein binding 2/157 70/18639 0.0285714285714286 3.39199272065514 0.117666187149012 0.291570328345225 GO:0020037 heme binding 3/157 142/18639 0.0211267605633803 2.50816363147035 0.118254572073752 0.291570328345225 GO:0000774 adenyl-nucleotide exchange factor activity 1/157 15/18639 0.0666666666666667 7.91464968152866 0.11920554860523 0.291570328345225 GO:0016846 carbon-sulfur lyase activity 1/157 15/18639 0.0666666666666667 7.91464968152866 0.11920554860523 0.291570328345225 GO:0017081 chloride channel regulator activity 1/157 15/18639 0.0666666666666667 7.91464968152866 0.11920554860523 0.291570328345225 GO:0050780 dopamine receptor binding 1/157 15/18639 0.0666666666666667 7.91464968152866 0.11920554860523 0.291570328345225 GO:0005159 insulin-like growth factor receptor binding 1/157 16/18639 0.0625 7.41998407643312 0.126630630696563 0.301239036684355 GO:0043023 ribosomal large subunit binding 1/157 16/18639 0.0625 7.41998407643312 0.126630630696563 0.301239036684355 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/157 16/18639 0.0625 7.41998407643312 0.126630630696563 0.301239036684355 GO:0055102 lipase inhibitor activity 1/157 16/18639 0.0625 7.41998407643312 0.126630630696563 0.301239036684355 GO:0044183 protein folding chaperone 2/157 75/18639 0.0266666666666667 3.16585987261147 0.131675839231664 0.301239036684355 GO:0030169 low-density lipoprotein particle binding 1/157 17/18639 0.0588235294117647 6.98351442487823 0.133993514817308 0.301239036684355 GO:0036041 long-chain fatty acid binding 1/157 17/18639 0.0588235294117647 6.98351442487823 0.133993514817308 0.301239036684355 GO:0048038 quinone binding 1/157 17/18639 0.0588235294117647 6.98351442487823 0.133993514817308 0.301239036684355 GO:1990226 histone methyltransferase binding 1/157 17/18639 0.0588235294117647 6.98351442487823 0.133993514817308 0.301239036684355 GO:0046906 tetrapyrrole binding 3/157 152/18639 0.0197368421052632 2.34315286624204 0.137002238907888 0.301239036684355 GO:0051540 metal cluster binding 2/157 77/18639 0.025974025974026 3.08362974605013 0.137382999898637 0.301239036684355 GO:0008525 phosphatidylcholine transporter activity 1/157 18/18639 0.0555555555555556 6.59554140127389 0.141294718671549 0.301239036684355 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/157 18/18639 0.0555555555555556 6.59554140127389 0.141294718671549 0.301239036684355 GO:0031690 adrenergic receptor binding 1/157 18/18639 0.0555555555555556 6.59554140127389 0.141294718671549 0.301239036684355 GO:0035615 clathrin adaptor activity 1/157 18/18639 0.0555555555555556 6.59554140127389 0.141294718671549 0.301239036684355 GO:0070064 proline-rich region binding 1/157 18/18639 0.0555555555555556 6.59554140127389 0.141294718671549 0.301239036684355 GO:1901611 phosphatidylglycerol binding 1/157 18/18639 0.0555555555555556 6.59554140127389 0.141294718671549 0.301239036684355 GO:0033293 monocarboxylic acid binding 2/157 79/18639 0.0253164556962025 3.00556317020076 0.143143917300094 0.301239036684355 GO:0000049 tRNA binding 2/157 80/18639 0.025 2.96799363057325 0.146043475602418 0.301239036684355 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/157 19/18639 0.0526315789473684 6.2484076433121 0.148534755681837 0.301239036684355 GO:0043395 heparan sulfate proteoglycan binding 1/157 19/18639 0.0526315789473684 6.2484076433121 0.148534755681837 0.301239036684355 GO:0046624 sphingolipid transporter activity 1/157 19/18639 0.0526315789473684 6.2484076433121 0.148534755681837 0.301239036684355 GO:0097001 ceramide binding 1/157 19/18639 0.0526315789473684 6.2484076433121 0.148534755681837 0.301239036684355 GO:0033192 calmodulin-dependent protein phosphatase activity 2/157 81/18639 0.0246913580246914 2.9313517338995 0.148955214272098 0.301239036684355 GO:0140791 histone H2AXS140 phosphatase activity 2/157 81/18639 0.0246913580246914 2.9313517338995 0.148955214272098 0.301239036684355 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/157 81/18639 0.0246913580246914 2.9313517338995 0.148955214272098 0.301239036684355 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/157 81/18639 0.0246913580246914 2.9313517338995 0.148955214272098 0.301239036684355 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/157 81/18639 0.0246913580246914 2.9313517338995 0.148955214272098 0.301239036684355 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/157 81/18639 0.0246913580246914 2.9313517338995 0.148955214272098 0.301239036684355 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/157 81/18639 0.0246913580246914 2.9313517338995 0.148955214272098 0.301239036684355 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/157 81/18639 0.0246913580246914 2.9313517338995 0.148955214272098 0.301239036684355 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/157 82/18639 0.024390243902439 2.89560354202268 0.151878726278907 0.303757452557813 GO:0033549 MAP kinase phosphatase activity 2/157 82/18639 0.024390243902439 2.89560354202268 0.151878726278907 0.303757452557813 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/157 83/18639 0.0240963855421687 2.86071675235976 0.154813610504048 0.307925972541019 GO:0043024 ribosomal small subunit binding 1/157 20/18639 0.05 5.9359872611465 0.155714135024369 0.308024682397933 GO:0017018 myosin phosphatase activity 2/157 84/18639 0.0238095238095238 2.82666060054595 0.157759471670528 0.308609850264401 GO:0042277 peptide binding 4/157 249/18639 0.0160642570281124 1.90714450157317 0.158973642754664 0.308609850264401 GO:0005123 death receptor binding 1/157 21/18639 0.0476190476190476 5.6533212010919 0.162833361663887 0.308609850264401 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/157 21/18639 0.0476190476190476 5.6533212010919 0.162833361663887 0.308609850264401 GO:0051428 peptide hormone receptor binding 1/157 21/18639 0.0476190476190476 5.6533212010919 0.162833361663887 0.308609850264401 GO:0070182 DNA polymerase binding 1/157 21/18639 0.0476190476190476 5.6533212010919 0.162833361663887 0.308609850264401 GO:0072542 protein phosphatase activator activity 1/157 21/18639 0.0476190476190476 5.6533212010919 0.162833361663887 0.308609850264401 GO:0140312 cargo adaptor activity 1/157 21/18639 0.0476190476190476 5.6533212010919 0.162833361663887 0.308609850264401 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/157 86/18639 0.0232558139534884 2.76092430751 0.163682572515926 0.308609850264401 GO:0031683 G-protein beta/gamma-subunit complex binding 1/157 22/18639 0.0454545454545455 5.39635205558772 0.169892936388281 0.31701671635339 GO:0140517 protein-RNA adaptor activity 1/157 22/18639 0.0454545454545455 5.39635205558772 0.169892936388281 0.31701671635339 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/157 89/18639 0.0224719101123595 2.66785944321191 0.172639997235516 0.318855505098248 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/157 89/18639 0.0224719101123595 2.66785944321191 0.172639997235516 0.318855505098248 GO:0140793 histone H2AXY142 phosphatase activity 2/157 90/18639 0.0222222222222222 2.63821656050955 0.17564373778572 0.32275651308848 GO:0099186 structural constituent of postsynapse 1/157 23/18639 0.0434782608695652 5.16172805317087 0.176893355842921 0.323411084924936 GO:0072341 modified amino acid binding 2/157 91/18639 0.021978021978022 2.60922516973472 0.178655846213529 0.324992041855766 GO:0070300 phosphatidic acid binding 1/157 24/18639 0.0416666666666667 4.94665605095541 0.183835112564701 0.332741553742109 GO:0019211 phosphatase activator activity 1/157 25/18639 0.04 4.7487898089172 0.190718695015808 0.343483420874241 GO:0016853 isomerase activity 3/157 180/18639 0.0166666666666667 1.97866242038217 0.194097031256608 0.34783725403412 GO:0043548 phosphatidylinositol 3-kinase binding 1/157 26/18639 0.0384615384615385 4.56614404703577 0.197544587617211 0.350544807438384 GO:0120014 phospholipid transfer activity 1/157 26/18639 0.0384615384615385 4.56614404703577 0.197544587617211 0.350544807438384 GO:0004725 protein tyrosine phosphatase activity 2/157 98/18639 0.0204081632653061 2.4228519433251 0.199946078356871 0.353075513976524 GO:1901981 phosphatidylinositol phosphate binding 3/157 185/18639 0.0162162162162162 1.92518505766913 0.204861769041563 0.359999807733233 GO:0046625 sphingolipid binding 1/157 28/18639 0.0357142857142857 4.23999090081893 0.21102522094776 0.365507798962149 GO:0051019 mitogen-activated protein kinase binding 1/157 28/18639 0.0357142857142857 4.23999090081893 0.21102522094776 0.365507798962149 GO:0097718 disordered domain specific binding 1/157 28/18639 0.0357142857142857 4.23999090081893 0.21102522094776 0.365507798962149 GO:0004722 protein serine/threonine phosphatase activity 2/157 103/18639 0.0194174757281553 2.30523777131903 0.215331221309251 0.371190010066422 GO:0001965 G-protein alpha-subunit binding 1/157 30/18639 0.0333333333333333 3.95732484076433 0.224280808355374 0.381172078049979 GO:0031210 phosphatidylcholine binding 1/157 30/18639 0.0333333333333333 3.95732484076433 0.224280808355374 0.381172078049979 GO:0098918 structural constituent of synapse 1/157 30/18639 0.0333333333333333 3.95732484076433 0.224280808355374 0.381172078049979 GO:0031369 translation initiation factor binding 1/157 32/18639 0.03125 3.70999203821656 0.237315083077637 0.396879546499253 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/157 32/18639 0.03125 3.70999203821656 0.237315083077637 0.396879546499253 GO:0051059 NF-kappaB binding 1/157 32/18639 0.03125 3.70999203821656 0.237315083077637 0.396879546499253 GO:0016829 lyase activity 3/157 200/18639 0.015 1.78079617834395 0.237908457431872 0.396879546499253 GO:1902936 phosphatidylinositol bisphosphate binding 2/157 111/18639 0.018018018018018 2.13909450852126 0.240151575913386 0.398783809544247 GO:0005543 phospholipid binding 6/157 497/18639 0.0120724346076459 1.4332363608402 0.242227458085483 0.400394245785136 GO:0140311 protein sequestering activity 1/157 33/18639 0.0303030303030303 3.59756803705848 0.243750377964336 0.401080167377681 GO:0019825 oxygen binding 1/157 34/18639 0.0294117647058824 3.49175721243912 0.250131716815223 0.407872439131129 GO:0030332 cyclin binding 1/157 34/18639 0.0294117647058824 3.49175721243912 0.250131716815223 0.407872439131129 GO:0005154 epidermal growth factor receptor binding 1/157 35/18639 0.0285714285714286 3.39199272065514 0.256459549143092 0.414456949954462 GO:0016229 steroid dehydrogenase activity 1/157 35/18639 0.0285714285714286 3.39199272065514 0.256459549143092 0.414456949954462 GO:0005484 SNAP receptor activity 1/157 36/18639 0.0277777777777778 3.29777070063694 0.262734320739767 0.420839929680512 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/157 36/18639 0.0277777777777778 3.29777070063694 0.262734320739767 0.420839929680512 GO:0030280 structural constituent of skin epidermis 1/157 37/18639 0.027027027027027 3.20864176278189 0.2689564737067 0.428908561593944 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/157 122/18639 0.0163934426229508 1.94622533152344 0.274467429872624 0.43491604204231 GO:0042162 telomeric DNA binding 1/157 38/18639 0.0263157894736842 3.12420382165605 0.275126446485329 0.43491604204231 GO:0050997 quaternary ammonium group binding 1/157 40/18639 0.025 2.96799363057325 0.287311587123722 0.448305148874083 GO:0071855 neuropeptide receptor binding 1/157 40/18639 0.025 2.96799363057325 0.287311587123722 0.448305148874083 GO:0140662 ATP-dependent protein folding chaperone 1/157 40/18639 0.025 2.96799363057325 0.287311587123722 0.448305148874083 GO:0004519 endonuclease activity 2/157 127/18639 0.015748031496063 1.86960228697527 0.290061769931834 0.450653908649459 GO:0042169 SH2 domain binding 1/157 41/18639 0.024390243902439 2.89560354202268 0.293327613835995 0.45184934556864 GO:0042287 MHC protein binding 1/157 41/18639 0.024390243902439 2.89560354202268 0.293327613835995 0.45184934556864 GO:0004520 DNA endonuclease activity 1/157 42/18639 0.0238095238095238 2.82666060054595 0.29929317812397 0.45332272167731 GO:0035198 miRNA binding 1/157 42/18639 0.0238095238095238 2.82666060054595 0.29929317812397 0.45332272167731 GO:0048487 beta-tubulin binding 1/157 42/18639 0.0238095238095238 2.82666060054595 0.29929317812397 0.45332272167731 GO:0051879 Hsp90 protein binding 1/157 42/18639 0.0238095238095238 2.82666060054595 0.29929317812397 0.45332272167731 GO:0031072 heat shock protein binding 2/157 131/18639 0.0152671755725191 1.8125151942432 0.302510304780333 0.455281436359022 GO:0003924 GTPase activity 4/157 331/18639 0.0120845921450151 1.43467970057921 0.304761542479787 0.455281436359022 GO:0005179 hormone activity 2/157 132/18639 0.0151515151515152 1.79878401852924 0.305617096782437 0.455281436359022 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/157 132/18639 0.0151515151515152 1.79878401852924 0.305617096782437 0.455281436359022 GO:0001046 core promoter sequence-specific DNA binding 1/157 44/18639 0.0227272727272727 2.69817602779386 0.311074598296142 0.459628590135523 GO:0001223 transcription coactivator binding 1/157 44/18639 0.0227272727272727 2.69817602779386 0.311074598296142 0.459628590135523 GO:0015297 antiporter activity 2/157 135/18639 0.0148148148148148 1.7588110403397 0.314921750104034 0.462338664698682 GO:0002020 protease binding 2/157 136/18639 0.0147058823529412 1.74587860621956 0.318017479309314 0.462338664698682 GO:0019838 growth factor binding 2/157 136/18639 0.0147058823529412 1.74587860621956 0.318017479309314 0.462338664698682 GO:0140789 histone phosphatase activity 2/157 136/18639 0.0147058823529412 1.74587860621956 0.318017479309314 0.462338664698682 GO:0030291 protein serine/threonine kinase inhibitor activity 1/157 46/18639 0.0217391304347826 2.58086402658543 0.322659170719822 0.467210479202302 GO:0001784 phosphotyrosine residue binding 1/157 47/18639 0.0212765957446809 2.52595202601979 0.328378662474622 0.473597911616785 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/157 48/18639 0.0208333333333333 2.47332802547771 0.334050163657468 0.479865711285728 GO:0060590 ATPase regulator activity 1/157 49/18639 0.0204081632653061 2.4228519433251 0.339674074383399 0.486015869275851 GO:0005006 epidermal growth factor receptor activity 1/157 50/18639 0.02 2.3743949044586 0.345250791452888 0.490120731395865 GO:0032813 tumor necrosis factor receptor superfamily binding 1/157 50/18639 0.02 2.3743949044586 0.345250791452888 0.490120731395865 GO:0030544 Hsp70 protein binding 1/157 51/18639 0.0196078431372549 2.32783814162608 0.35078070837913 0.496025845442363 GO:0045182 translation regulator activity 4/157 356/18639 0.0112359550561798 1.33392972160595 0.352436856319247 0.496428568045009 GO:0019209 kinase activator activity 2/157 148/18639 0.0135135135135135 1.60432088139095 0.354871963003624 0.49792112638493 GO:0005544 calcium-dependent phospholipid binding 1/157 53/18639 0.0188679245283019 2.23999519288547 0.36170169958036 0.503363118094561 GO:0051018 protein kinase A binding 1/157 53/18639 0.0188679245283019 2.23999519288547 0.36170169958036 0.503363118094561 GO:0003713 transcription coactivator activity 3/157 256/18639 0.01171875 1.39124701433121 0.366007373566326 0.503363118094561 GO:0003925 G protein activity 1/157 54/18639 0.0185185185185185 2.19851380042463 0.367093544687746 0.503363118094561 GO:0050661 NADP binding 1/157 54/18639 0.0185185185185185 2.19851380042463 0.367093544687746 0.503363118094561 GO:0051287 NAD binding 1/157 54/18639 0.0185185185185185 2.19851380042463 0.367093544687746 0.503363118094561 GO:0140313 molecular sequestering activity 1/157 55/18639 0.0181818181818182 2.15854082223509 0.372440131369695 0.508767273795584 GO:0003730 mRNA 3'-UTR binding 3/157 262/18639 0.0114503816793893 1.3593863956824 0.379738867668256 0.516787481563566 GO:0061980 regulatory RNA binding 1/157 58/18639 0.0172413793103448 2.04689215901603 0.38821210003017 0.525476256765485 GO:0099106 ion channel regulator activity 2/157 160/18639 0.0125 1.48399681528662 0.391012684274525 0.525476256765485 GO:0001786 phosphatidylserine binding 1/157 59/18639 0.0169491525423729 2.01219907157508 0.393381396639355 0.525476256765485 GO:0045309 protein phosphorylated amino acid binding 1/157 59/18639 0.0169491525423729 2.01219907157508 0.393381396639355 0.525476256765485 GO:0070063 RNA polymerase binding 1/157 59/18639 0.0169491525423729 2.01219907157508 0.393381396639355 0.525476256765485 GO:0008083 growth factor activity 2/157 162/18639 0.0123456790123457 1.46567586694975 0.396951614454845 0.528295898649463 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/157 60/18639 0.0166666666666667 1.97866242038217 0.398507291188743 0.528423587583607 GO:0019905 syntaxin binding 1/157 61/18639 0.0163934426229508 1.94622533152344 0.403590145770979 0.533210338573337 GO:0016874 ligase activity 2/157 167/18639 0.0119760479041916 1.42179335596323 0.411681499735053 0.541832426403299 GO:0005507 copper ion binding 1/157 63/18639 0.0158730158730159 1.88444040036397 0.413628168421694 0.541832426403299 GO:0016247 channel regulator activity 2/157 168/18639 0.0119047619047619 1.41333030027298 0.414606580424624 0.541832426403299 GO:0004536 DNA nuclease activity 1/157 64/18639 0.015625 1.85499601910828 0.418584045766536 0.545062678300309 GO:0141108 transporter regulator activity 2/157 170/18639 0.0117647058823529 1.39670288497565 0.420435122636454 0.54551080428099 GO:0038024 cargo receptor activity 1/157 65/18639 0.0153846153846154 1.82645761881431 0.423498301745791 0.547522804399915 GO:0035091 phosphatidylinositol binding 3/157 284/18639 0.0105633802816901 1.25408181573518 0.429455170706046 0.553248298204941 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/157 67/18639 0.0149253731343284 1.77193649586463 0.433203336048525 0.556097899466546 GO:0004721 phosphoprotein phosphatase activity 2/157 175/18639 0.0114285714285714 1.35679708826206 0.434876448343208 0.556273054064457 GO:0005548 phospholipid transporter activity 1/157 68/18639 0.0147058823529412 1.74587860621956 0.437994800416411 0.558289147009651 GO:0005319 lipid transporter activity 2/157 178/18639 0.0112359550561798 1.33392972160595 0.443448929316416 0.563257938289623 GO:0004521 RNA endonuclease activity 1/157 73/18639 0.0136986301369863 1.62629787976616 0.461355061199969 0.583952909630731 GO:0003684 damaged DNA binding 1/157 74/18639 0.0135135135135135 1.60432088139095 0.465910014091901 0.585623003823848 GO:0035064 methylated histone binding 1/157 74/18639 0.0135135135135135 1.60432088139095 0.465910014091901 0.585623003823848 GO:0008234 cysteine-type peptidase activity 2/157 187/18639 0.0106951871657754 1.26972989543241 0.468729443115641 0.586743208842143 GO:0003725 double-stranded RNA binding 1/157 75/18639 0.0133333333333333 1.58292993630573 0.470426692130553 0.586743208842143 GO:0017022 myosin binding 1/157 76/18639 0.0131578947368421 1.56210191082803 0.474905414891569 0.586743208842143 GO:0051536 iron-sulfur cluster binding 1/157 76/18639 0.0131578947368421 1.56210191082803 0.474905414891569 0.586743208842143 GO:0140034 methylation-dependent protein binding 1/157 76/18639 0.0131578947368421 1.56210191082803 0.474905414891569 0.586743208842143 GO:0019199 transmembrane receptor protein kinase activity 1/157 78/18639 0.0128205128205128 1.52204801567859 0.48375025964901 0.595638074805924 GO:0016835 carbon-oxygen lyase activity 1/157 79/18639 0.0126582278481013 1.50278158510038 0.488117007627842 0.596953907977294 GO:0046332 SMAD binding 1/157 79/18639 0.0126582278481013 1.50278158510038 0.488117007627842 0.596953907977294 GO:0001618 virus receptor activity 1/157 81/18639 0.0123456790123457 1.46567586694975 0.496740700312836 0.603423266822975 GO:0030971 receptor tyrosine kinase binding 1/157 81/18639 0.0123456790123457 1.46567586694975 0.496740700312836 0.603423266822975 GO:0140272 exogenous protein binding 1/157 82/18639 0.0121951219512195 1.44780177101134 0.500998255547823 0.606559760897364 GO:0003779 actin binding 4/157 443/18639 0.0090293453724605 1.07196158214835 0.514851671935998 0.621254350802771 GO:0005516 calmodulin binding 2/157 207/18639 0.00966183574879227 1.14705067848241 0.522390273411293 0.628207526503325 GO:0004197 cysteine-type endopeptidase activity 1/157 88/18639 0.0113636363636364 1.34908801389693 0.525802347721941 0.628207526503325 GO:0004518 nuclease activity 2/157 209/18639 0.00956937799043062 1.13607411696584 0.527555491870195 0.628207526503325 GO:0051015 actin filament binding 2/157 209/18639 0.00956937799043062 1.13607411696584 0.527555491870195 0.628207526503325 GO:0051219 phosphoprotein binding 1/157 93/18639 0.010752688172043 1.27655640024656 0.545533699960477 0.647485899625222 GO:0004896 cytokine receptor activity 1/157 96/18639 0.0104166666666667 1.23666401273885 0.556978649342841 0.65890938255591 GO:0000149 SNARE binding 1/157 106/18639 0.00943396226415094 1.11999759644274 0.593099495154369 0.699355105035444 GO:0019888 protein phosphatase regulator activity 1/157 107/18639 0.00934579439252336 1.10953032918626 0.596546502075038 0.701135823867415 GO:0005496 steroid binding 1/157 108/18639 0.00925925925925926 1.09925690021231 0.599964492533392 0.702871023615172 GO:0005200 structural constituent of cytoskeleton 1/157 112/18639 0.00892857142857143 1.05999772520473 0.613351113671429 0.716235816609863 GO:0005525 GTP binding 3/157 378/18639 0.00793650793650794 0.942220200181983 0.620331560905339 0.718348764836529 GO:0140104 molecular carrier activity 2/157 249/18639 0.00803212851405622 0.953572250786586 0.622798074645857 0.718348764836529 GO:0001221 transcription coregulator binding 1/157 115/18639 0.00869565217391304 1.03234561063417 0.623098099885829 0.718348764836529 GO:0017124 SH3 domain binding 1/157 115/18639 0.00869565217391304 1.03234561063417 0.623098099885829 0.718348764836529 GO:0019208 phosphatase regulator activity 1/157 117/18639 0.00854700854700855 1.01469867711906 0.629460054045093 0.721090315076974 GO:1990782 protein tyrosine kinase binding 1/157 117/18639 0.00854700854700855 1.01469867711906 0.629460054045093 0.721090315076974 GO:0015631 tubulin binding 3/157 385/18639 0.00779220779220779 0.925088923815038 0.632719925869842 0.722538211876602 GO:0003697 single-stranded DNA binding 1/157 121/18639 0.00826446280991736 0.981154919197768 0.641865596864754 0.728386664780692 GO:0004540 RNA nuclease activity 1/157 121/18639 0.00826446280991736 0.981154919197768 0.641865596864754 0.728386664780692 GO:0019001 guanyl nucleotide binding 3/157 400/18639 0.0075 0.890398089171974 0.65832213315342 0.739358930875187 GO:0032561 guanyl ribonucleotide binding 3/157 400/18639 0.0075 0.890398089171974 0.65832213315342 0.739358930875187 GO:0019783 ubiquitin-like protein peptidase activity 1/157 127/18639 0.0078740157480315 0.934801143487637 0.659704239427308 0.739358930875187 GO:0042826 histone deacetylase binding 1/157 127/18639 0.0078740157480315 0.934801143487637 0.659704239427308 0.739358930875187 GO:0008514 organic anion transmembrane transporter activity 2/157 269/18639 0.00743494423791822 0.882674685672342 0.664605878635188 0.741211155463267 GO:0035591 signaling adaptor activity 1/157 129/18639 0.00775193798449612 0.920308102503333 0.665452004214259 0.741211155463267 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/157 130/18639 0.00769230769230769 0.913228809407153 0.668289607420005 0.742088459773134 GO:0016791 phosphatase activity 2/157 273/18639 0.00732600732600733 0.869741723244908 0.672509116650258 0.744490214762671 GO:0005126 cytokine receptor binding 2/157 275/18639 0.00727272727272727 0.863416328894036 0.676404240061192 0.745284340929545 GO:0008017 microtubule binding 2/157 276/18639 0.0072463768115942 0.860288008861811 0.678337740935732 0.745284340929545 GO:0051087 protein-folding chaperone binding 1/157 134/18639 0.00746268656716418 0.885968247932313 0.67940285222859 0.745284340929545 GO:0044325 transmembrane transporter binding 1/157 136/18639 0.00735294117647059 0.872939303109779 0.684819937350764 0.74895715202712 GO:0030295 protein kinase activator activity 1/157 139/18639 0.00719424460431655 0.854098886495899 0.692775493058781 0.753107292754591 GO:0070851 growth factor receptor binding 1/157 139/18639 0.00719424460431655 0.854098886495899 0.692775493058781 0.753107292754591 GO:0004713 protein tyrosine kinase activity 1/157 140/18639 0.00714285714285714 0.847998180163785 0.695382749685255 0.753678309539109 GO:0015291 secondary active transmembrane transporter activity 2/157 287/18639 0.00696864111498258 0.827315297720766 0.698993605708613 0.755330403780651 GO:0019903 protein phosphatase binding 1/157 144/18639 0.00694444444444444 0.824442675159236 0.705593743824863 0.757937493366767 GO:0019955 cytokine binding 1/157 144/18639 0.00694444444444444 0.824442675159236 0.705593743824863 0.757937493366767 GO:0019842 vitamin binding 1/157 150/18639 0.00666666666666667 0.791464968152866 0.720275945298718 0.771419799402768 GO:0140375 immune receptor activity 1/157 156/18639 0.00641025641025641 0.761024007839294 0.734230368970176 0.784045408752814 GO:0051020 GTPase binding 2/157 315/18639 0.00634920634920635 0.753776160145587 0.746668438297089 0.794982278422194 GO:0140713 histone chaperone activity 1/157 164/18639 0.00609756097560976 0.72390088550567 0.751765885808469 0.798062318658844 GO:0140030 modification-dependent protein binding 1/157 173/18639 0.00578034682080925 0.686241301866647 0.770122387211569 0.815158784124526 GO:0140297 DNA-binding transcription factor binding 3/157 488/18639 0.00614754098360656 0.729834499321291 0.782742851982111 0.826101785473832 GO:0005261 monoatomic cation channel activity 2/157 341/18639 0.00586510263929619 0.696303491043577 0.785029734168269 0.82610687142126 GO:0003712 transcription coregulator activity 3/157 495/18639 0.00606060606060606 0.719513607411697 0.790828276945725 0.82979662682421 GO:0140597 protein carrier chaperone 1/157 188/18639 0.00531914893617021 0.631488006504947 0.797766828124021 0.834657779713571 GO:0019902 phosphatase binding 1/157 190/18639 0.00526315789473684 0.62484076433121 0.801193891998273 0.835827633727305 GO:0042578 phosphoric ester hydrolase activity 2/157 363/18639 0.00550964187327824 0.654103279465179 0.813432202879517 0.846156486903406 GO:0005085 guanyl-nucleotide exchange factor activity 1/157 230/18639 0.00434782608695652 0.516172805317087 0.858809207750714 0.890799235546586 GO:0005125 cytokine activity 1/157 234/18639 0.00427350427350427 0.50734933855953 0.863564870661869 0.893172809084561 GO:0016887 ATP hydrolysis activity 2/157 417/18639 0.00479616306954436 0.569399257663933 0.869482526924726 0.896731267084761 GO:0005216 monoatomic ion channel activity 2/157 448/18639 0.00446428571428571 0.529998862602366 0.894255201189036 0.919660178495542 GO:0005096 GTPase activator activity 1/157 271/18639 0.003690036900369 0.438080240675018 0.900658552076616 0.923621517993583 GO:0031267 small GTPase binding 1/157 283/18639 0.00353356890459364 0.419504400081025 0.910385123539866 0.930958798648112 GO:0030695 GTPase regulator activity 2/157 489/18639 0.00408997955010225 0.485561330155133 0.920369530964659 0.93382209695217 GO:0001664 G protein-coupled receptor binding 1/157 297/18639 0.00336700336700337 0.399729781895387 0.920542629065106 0.93382209695217 GO:0060589 nucleoside-triphosphatase regulator activity 2/157 490/18639 0.00408163265306122 0.48457038866502 0.920924001690399 0.93382209695217 GO:0140097 catalytic activity, acting on DNA 1/157 336/18639 0.00297619047619048 0.353332575068244 0.943195788280392 0.953734288708106 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 1/157 349/18639 0.00286532951289398 0.340171189750516 0.949216027978878 0.957148195343604 GO:0046982 protein heterodimerization activity 1/157 369/18639 0.002710027100271 0.321733726891409 0.957262737788951 0.962580864110001 GO:0140098 catalytic activity, acting on RNA 1/157 387/18639 0.00258397932816537 0.306769367501111 0.96341456117092 0.966083299567515 GO:0004175 endopeptidase activity 1/157 405/18639 0.00246913580246914 0.29313517338995 0.968685682282598 0.968685682282598