ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 35/52 175/18639 0.2 71.6884615384615 5.72827071466544e-60 6.35838049327864e-58 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 8/52 68/18639 0.117647058823529 42.1696832579186 1.35921745108503e-11 7.54365685352192e-10 GO:0019843 rRNA binding 7/52 65/18639 0.107692307692308 38.6014792899408 5.31846644843431e-10 1.96783258592069e-08 GO:0009055 electron transfer activity 8/52 116/18639 0.0689655172413793 24.7201591511936 1.05589116498674e-09 2.68776487640876e-08 GO:0022853 active monoatomic ion transmembrane transporter activity 8/52 118/18639 0.0677966101694915 24.3011734028683 1.21070489928323e-09 2.68776487640876e-08 GO:0015078 proton transmembrane transporter activity 9/52 185/18639 0.0486486486486487 17.4377338877339 1.95955886968156e-09 3.62518390891089e-08 GO:0015399 primary active transmembrane transporter activity 8/52 166/18639 0.0481927710843374 17.274328081557 1.80235458109936e-08 2.85801940717185e-07 GO:0008137 NADH dehydrogenase (ubiquinone) activity 4/52 41/18639 0.0975609756097561 34.9699812382739 5.05299080047439e-06 7.01102473565822e-05 GO:0003954 NADH dehydrogenase activity 4/52 44/18639 0.0909090909090909 32.5856643356643 6.73174291153017e-06 8.30248292422055e-05 GO:0004129 cytochrome-c oxidase activity 3/52 15/18639 0.2 71.6884615384615 9.10070021367924e-06 0.00010101777237184 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/52 16/18639 0.1875 67.2079326923077 1.11787974807322e-05 0.000112804229123753 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 4/52 58/18639 0.0689655172413793 24.7201591511936 2.0441360856463e-05 0.000189082587922282 GO:0022804 active transmembrane transporter activity 8/52 457/18639 0.0175054704595186 6.27470122874937 3.5870494103852e-05 0.000306278834271352 GO:0016651 oxidoreductase activity, acting on NAD(P)H 4/52 88/18639 0.0454545454545455 16.2928321678322 0.000105628167013642 0.00083748046703673 GO:0008199 ferric iron binding 2/52 11/18639 0.181818181818182 65.1713286713287 0.000413163879527816 0.00286632441422422 GO:1990948 ubiquitin ligase inhibitor activity 2/52 11/18639 0.181818181818182 65.1713286713287 0.000413163879527816 0.00286632441422422 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/52 15/18639 0.133333333333333 47.7923076923077 0.000783150370245578 0.00511351124101524 GO:0017134 fibroblast growth factor binding 2/52 23/18639 0.0869565217391304 31.1688963210702 0.00186026881451044 0.0114716576894811 GO:0008198 ferrous iron binding 2/52 26/18639 0.0769230769230769 27.5724852071006 0.00237692610411031 0.0138862525029602 GO:0055106 ubiquitin-protein transferase regulator activity 2/52 36/18639 0.0555555555555556 19.9134615384615 0.0045262593239685 0.0251207392480252 GO:0045296 cadherin binding 4/52 334/18639 0.0119760479041916 4.29272224781207 0.013957767258213 0.0737767697934113 GO:0001540 amyloid-beta binding 2/52 83/18639 0.0240963855421687 8.6371640407785 0.0224962874918658 0.113503995981687 GO:0032356 oxidized DNA binding 1/52 10/18639 0.1 35.8442307692308 0.0275574092595812 0.132994453383196 GO:0050998 nitric-oxide synthase binding 1/52 11/18639 0.0909090909090909 32.5856643356643 0.0302718337975871 0.14000723131384 GO:0097371 MDM2/MDM4 family protein binding 1/52 12/18639 0.0833333333333333 29.8701923076923 0.0329788267459724 0.146425990752118 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/52 13/18639 0.0769230769230769 27.5724852071006 0.0356784080531719 0.152319357457772 GO:0016722 oxidoreductase activity, acting on metal ions 1/52 16/18639 0.0625 22.4026442307692 0.0437328808256237 0.175687342889288 GO:0048038 quinone binding 1/52 17/18639 0.0588235294117647 21.0848416289593 0.0464030140048682 0.175687342889288 GO:0004519 endonuclease activity 2/52 127/18639 0.015748031496063 5.64476075105996 0.0489611384604887 0.175687342889288 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/52 18/18639 0.0555555555555556 19.9134615384615 0.0490658345006119 0.175687342889288 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/52 18/18639 0.0555555555555556 19.9134615384615 0.0490658345006119 0.175687342889288 GO:0043395 heparan sulfate proteoglycan binding 1/52 19/18639 0.0526315789473684 18.8653846153846 0.0517213619484381 0.179408474258645 GO:0019838 growth factor binding 2/52 136/18639 0.0147058823529412 5.27121040723982 0.0553000707258391 0.186009328805095 GO:0048027 mRNA 5'-UTR binding 1/52 24/18639 0.0416666666666667 14.9350961538462 0.0648902871045411 0.201757404761672 GO:0120020 cholesterol transfer activity 1/52 25/18639 0.04 14.3376923076923 0.0675024657277248 0.201757404761672 GO:0005506 iron ion binding 2/52 154/18639 0.012987012987013 4.6550949050949 0.0687787799680642 0.201757404761672 GO:0050750 low-density lipoprotein particle receptor binding 1/52 26/18639 0.0384615384615385 13.7862426035503 0.0701074873126692 0.201757404761672 GO:0015252 proton channel activity 1/52 27/18639 0.037037037037037 13.275641025641 0.0727053710852873 0.201757404761672 GO:0023026 MHC class II protein complex binding 1/52 27/18639 0.037037037037037 13.275641025641 0.0727053710852873 0.201757404761672 GO:0035255 ionotropic glutamate receptor binding 1/52 27/18639 0.037037037037037 13.275641025641 0.0727053710852873 0.201757404761672 GO:0045182 translation regulator activity 3/52 356/18639 0.00842696629213483 3.0205812445981 0.0770054617857744 0.206528511455199 GO:0070325 lipoprotein particle receptor binding 1/52 31/18639 0.032258064516129 11.5626550868486 0.0830259108019187 0.206528511455199 GO:0008201 heparin binding 2/52 172/18639 0.0116279069767442 4.16793381037567 0.0832160257548081 0.206528511455199 GO:0071813 lipoprotein particle binding 1/52 32/18639 0.03125 11.2013221153846 0.0855883921345871 0.206528511455199 GO:0071814 protein-lipid complex binding 1/52 32/18639 0.03125 11.2013221153846 0.0855883921345871 0.206528511455199 GO:0120015 sterol transfer activity 1/52 32/18639 0.03125 11.2013221153846 0.0855883921345871 0.206528511455199 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/52 36/18639 0.0277777777777778 9.95673076923077 0.0957682708077884 0.222670129225192 GO:0023023 MHC protein complex binding 1/52 37/18639 0.027027027027027 9.68762993762994 0.0982958228111209 0.222670129225192 GO:0043394 proteoglycan binding 1/52 37/18639 0.027027027027027 9.68762993762994 0.0982958228111209 0.222670129225192 GO:0016829 lyase activity 2/52 200/18639 0.01 3.58442307692308 0.107293760757263 0.229523612940648 GO:0042287 MHC protein binding 1/52 41/18639 0.024390243902439 8.74249530956848 0.108336920455808 0.229523612940648 GO:0004520 DNA endonuclease activity 1/52 42/18639 0.0238095238095238 8.53434065934066 0.110830010042661 0.229523612940648 GO:0051879 Hsp90 protein binding 1/52 42/18639 0.0238095238095238 8.53434065934066 0.110830010042661 0.229523612940648 GO:0048156 tau protein binding 1/52 43/18639 0.0232558139534884 8.33586762075134 0.113316262635971 0.229523612940648 GO:0004518 nuclease activity 2/52 209/18639 0.00956937799043062 3.43006993006993 0.115393297474973 0.229523612940648 GO:0001223 transcription coactivator binding 1/52 44/18639 0.0227272727272727 8.14641608391608 0.115795696618705 0.229523612940648 GO:0035254 glutamate receptor binding 1/52 49/18639 0.0204081632653061 7.31514913657771 0.128091227393741 0.249440811240443 GO:0030544 Hsp70 protein binding 1/52 51/18639 0.0196078431372549 7.02828054298642 0.132962347429848 0.254462423529537 GO:0051018 protein kinase A binding 1/52 53/18639 0.0188679245283019 6.76306240928882 0.137806774297502 0.259263592322419 GO:0140313 molecular sequestering activity 1/52 55/18639 0.0181818181818182 6.51713286713287 0.142624651419417 0.263855605125922 GO:0005539 glycosaminoglycan binding 2/52 242/18639 0.00826446280991736 2.96233312142403 0.14631007079631 0.266236358334268 GO:0033218 amide binding 2/52 247/18639 0.00809716599190283 2.90236686390533 0.151137722791944 0.269708743049864 GO:0042277 peptide binding 2/52 249/18639 0.00803212851405622 2.8790546802595 0.153077935244518 0.269708743049864 GO:0005507 copper ion binding 1/52 63/18639 0.0158730158730159 5.68956043956044 0.161633504550806 0.279721274794402 GO:0004536 DNA nuclease activity 1/52 64/18639 0.015625 5.60066105769231 0.163980353052279 0.279721274794402 GO:0120013 lipid transfer activity 1/52 65/18639 0.0153846153846154 5.51449704142012 0.166320757985861 0.279721274794402 GO:0050840 extracellular matrix binding 1/52 67/18639 0.0149253731343284 5.34988518943743 0.170982306486252 0.28326919432797 GO:1901681 sulfur compound binding 2/52 275/18639 0.00727272727272727 2.60685314685315 0.178720722292496 0.29173529668334 GO:0004521 RNA endonuclease activity 1/52 73/18639 0.0136986301369863 4.91016859852476 0.184814100910044 0.294848368122738 GO:0003684 damaged DNA binding 1/52 74/18639 0.0135135135135135 4.84381496881497 0.187097288820886 0.294848368122738 GO:0044183 protein folding chaperone 1/52 75/18639 0.0133333333333333 4.77923076923077 0.189374204575333 0.294848368122738 GO:0051536 iron-sulfur cluster binding 1/52 76/18639 0.0131578947368421 4.71634615384615 0.191644865066719 0.294848368122738 GO:0051540 metal cluster binding 1/52 77/18639 0.012987012987013 4.6550949050949 0.193909287143782 0.294848368122738 GO:0016835 carbon-oxygen lyase activity 1/52 79/18639 0.0126582278481013 4.53724440116845 0.19841948322763 0.29698463025075 GO:0000049 tRNA binding 1/52 80/18639 0.0125 4.48052884615385 0.200665290709966 0.29698463025075 GO:0016209 antioxidant activity 1/52 86/18639 0.0116279069767442 4.16793381037567 0.214011115309443 0.312568865780896 GO:0004896 cytokine receptor activity 1/52 96/18639 0.0104166666666667 3.73377403846154 0.235770094366134 0.339876369800531 GO:0001221 transcription coregulator binding 1/52 115/18639 0.00869565217391304 3.11688963210702 0.275496707290488 0.392053006528771 GO:0004540 RNA nuclease activity 1/52 121/18639 0.00826446280991736 2.96233312142403 0.287615832376502 0.40411844802268 GO:0031072 heat shock protein binding 1/52 131/18639 0.00763358778625954 2.73620082207868 0.307373983332496 0.426481401873838 GO:0051087 protein-folding chaperone binding 1/52 134/18639 0.00746268656716418 2.67494259471871 0.313195907516482 0.429194391781846 GO:0030295 protein kinase activator activity 1/52 139/18639 0.00719424460431655 2.57872163807416 0.322792632203112 0.433033580678965 GO:0004857 enzyme inhibitor activity 2/52 416/18639 0.00480769230769231 1.72328032544379 0.323799884651839 0.433033580678965 GO:0020037 heme binding 1/52 142/18639 0.00704225352112676 2.52424160346696 0.328487408434256 0.433889604260545 GO:0019955 cytokine binding 1/52 144/18639 0.00694444444444444 2.48918269230769 0.332257805064381 0.433889604260545 GO:0019209 kinase activator activity 1/52 148/18639 0.00675675675675676 2.42190748440748 0.339736415208316 0.438497001024688 GO:0046906 tetrapyrrole binding 1/52 152/18639 0.00657894736842105 2.35817307692308 0.347132859108563 0.442893647828167 GO:0140375 immune receptor activity 1/52 156/18639 0.00641025641025641 2.29770710059172 0.354448022001907 0.447087845934224 GO:0005178 integrin binding 1/52 161/18639 0.0062111801242236 2.2263497372193 0.363479007681301 0.453327751153083 GO:0016874 ligase activity 1/52 167/18639 0.00598802395209581 2.14636112390603 0.374152732578717 0.461455036847084 GO:0004252 serine-type endopeptidase activity 1/52 176/18639 0.00568181818181818 2.03660402097902 0.3898349556423 0.469383431548229 GO:0043021 ribonucleoprotein complex binding 1/52 177/18639 0.00564971751412429 2.02509778357236 0.391553451136347 0.469383431548229 GO:0005319 lipid transporter activity 1/52 178/18639 0.00561797752808989 2.01372082973207 0.393267199405273 0.469383431548229 GO:0008236 serine-type peptidase activity 1/52 194/18639 0.00515463917525773 1.84764076130055 0.420051937087629 0.496018776773689 GO:0017171 serine hydrolase activity 1/52 198/18639 0.00505050505050505 1.81031468531469 0.426564800639813 0.49840729337915 GO:0005125 cytokine activity 1/52 234/18639 0.00427350427350427 1.53180473372781 0.482043178342888 0.557362424958964 GO:0019887 protein kinase regulator activity 1/52 255/18639 0.00392156862745098 1.40565610859728 0.51193731340738 0.58141100183702 GO:0003713 transcription coactivator activity 1/52 256/18639 0.00390625 1.40016526442308 0.513317821441693 0.58141100183702 GO:0008017 microtubule binding 1/52 276/18639 0.0036231884057971 1.29870401337793 0.54013738406138 0.605608582129426 GO:0019207 kinase regulator activity 1/52 287/18639 0.00348432055749129 1.24892790136693 0.554264604303538 0.615233710776927 GO:0031625 ubiquitin protein ligase binding 1/52 302/18639 0.0033112582781457 1.1868950585838 0.572845096790113 0.629562433105965 GO:0044389 ubiquitin-like protein ligase binding 1/52 322/18639 0.0031055900621118 1.11317486860965 0.596441793502648 0.649069010576411 GO:0140097 catalytic activity, acting on DNA 1/52 336/18639 0.00297619047619048 1.06679258241758 0.61219386659454 0.659246246764881 GO:0005261 monoatomic cation channel activity 1/52 341/18639 0.00293255131964809 1.05115046244079 0.617672159131059 0.659246246764881 GO:0015631 tubulin binding 1/52 385/18639 0.0025974025974026 0.931018981018981 0.662720525151245 0.695990367880815 GO:0140098 catalytic activity, acting on RNA 1/52 387/18639 0.00258397932816537 0.926207513416816 0.664639450408706 0.695990367880815 GO:0004175 endopeptidase activity 1/52 405/18639 0.00246913580246914 0.885042735042735 0.681434847966642 0.706909047890629 GO:0005216 monoatomic ion channel activity 1/52 448/18639 0.00223214285714286 0.800094436813187 0.718288946860688 0.738241417606818 GO:0140297 DNA-binding transcription factor binding 1/52 488/18639 0.00204918032786885 0.734512925598991 0.748799150796568 0.755203706973902 GO:0003712 transcription coregulator activity 1/52 495/18639 0.00202020202020202 0.724125874125874 0.753794459407417 0.755203706973902 GO:0005543 phospholipid binding 1/52 497/18639 0.00201207243460765 0.721211886704844 0.755203706973902 0.755203706973902