ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0015453 oxidoreduction-driven active transmembrane transporter activity 8/22 68/18639 0.117647058823529 99.6737967914439 6.29449668443364e-15 6.35744165127797e-13 GO:0015078 proton transmembrane transporter activity 9/22 185/18639 0.0486486486486487 41.2164619164619 3.42192778106891e-13 1.52099997802007e-11 GO:0009055 electron transfer activity 8/22 116/18639 0.0689655172413793 58.4294670846395 5.23844059137647e-13 1.52099997802007e-11 GO:0022853 active monoatomic ion transmembrane transporter activity 8/22 118/18639 0.0677966101694915 57.4391371340524 6.02376228918841e-13 1.52099997802007e-11 GO:0015399 primary active transmembrane transporter activity 8/22 166/18639 0.0481927710843374 40.8302300109529 9.60722851201931e-12 1.9406601594279e-10 GO:0022804 active transmembrane transporter activity 9/22 457/18639 0.0196936542669584 16.685000994629 1.10963622894127e-09 1.86788765205114e-08 GO:0004129 cytochrome-c oxidase activity 4/22 15/18639 0.266666666666667 225.927272727273 1.96931134207570e-09 2.8414349364235e-08 GO:0016675 oxidoreductase activity, acting on a heme group of donors 4/22 16/18639 0.25 211.806818181818 2.62371915883026e-09 3.31244543802321e-08 GO:0003735 structural constituent of ribosome 4/22 175/18639 0.0228571428571429 19.3651948051948 4.81235679411313e-05 0.000540053373561585 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/22 15/18639 0.133333333333333 112.963636363636 0.000138347067059463 0.00139730537730058 GO:0055106 ubiquitin-protein transferase regulator activity 2/22 36/18639 0.0555555555555556 47.0681818181818 0.00081771418222121 0.0075081029458493 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/22 41/18639 0.0487804878048781 41.3281596452328 0.00106053141949174 0.00892613944738881 GO:0003954 NADH dehydrogenase activity 2/22 44/18639 0.0454545454545455 38.5103305785124 0.00122087228506897 0.00948523852245895 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/22 58/18639 0.0344827586206897 29.2147335423197 0.00211208344372507 0.0152371734154451 GO:0005507 copper ion binding 2/22 63/18639 0.0317460317460317 26.8961038961039 0.00248651392507962 0.0167425270955361 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/22 88/18639 0.0227272727272727 19.2551652892562 0.00478760930196318 0.0302217837186426 GO:0005131 growth hormone receptor binding 1/22 10/18639 0.1 84.7227272727273 0.0117435336331985 0.0646234251287185 GO:0020037 heme binding 2/22 142/18639 0.0140845070422535 11.9327784891165 0.0120485872229396 0.0646234251287185 GO:0004857 enzyme inhibitor activity 3/22 416/18639 0.00721153846153846 6.10981206293706 0.0124037771627642 0.0646234251287185 GO:1990948 ubiquitin ligase inhibitor activity 1/22 11/18639 0.0909090909090909 77.0206611570248 0.0129106194810739 0.0646234251287185 GO:0046906 tetrapyrrole binding 2/22 152/18639 0.0131578947368421 11.1477272727273 0.0137139968902184 0.0646234251287185 GO:0097371 MDM2/MDM4 family protein binding 1/22 12/18639 0.0833333333333333 70.6022727272727 0.0140763896319981 0.0646234251287185 GO:0005542 folic acid binding 1/22 13/18639 0.0769230769230769 65.1713286713287 0.0152408454986482 0.0651098298933569 GO:0008083 growth factor activity 2/22 162/18639 0.0123456790123457 10.459595959596 0.0154739397103652 0.0651098298933569 GO:0016530 metallochaperone activity 1/22 14/18639 0.0714285714285714 60.5162337662338 0.0164039884922611 0.0651098298933569 GO:0030414 peptidase inhibitor activity 2/22 169/18639 0.0118343195266272 10.0263582571275 0.016760946309181 0.0651098298933569 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/22 18/18639 0.0555555555555556 47.0681818181818 0.0210434599107007 0.075906766106456 GO:1990381 ubiquitin-specific protease binding 1/22 18/18639 0.0555555555555556 47.0681818181818 0.0210434599107007 0.075906766106456 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/22 19/18639 0.0526315789473684 44.5909090909091 0.0222000596573285 0.0773174491513855 GO:0000295 adenine nucleotide transmembrane transporter activity 1/22 23/18639 0.0434782608695652 36.8359683794466 0.0268134282905271 0.0857299340967153 GO:0061134 peptidase regulator activity 2/22 226/18639 0.00884955752212389 7.49758648431215 0.0288307757227587 0.0857299340967153 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/22 25/18639 0.04 33.8890909090909 0.0291123139767596 0.0857299340967153 GO:0019707 protein-cysteine S-acyltransferase activity 1/22 25/18639 0.04 33.8890909090909 0.0291123139767596 0.0857299340967153 GO:0015216 purine nucleotide transmembrane transporter activity 1/22 26/18639 0.0384615384615385 32.5856643356643 0.0302598120477013 0.0857299340967153 GO:0050681 nuclear androgen receptor binding 1/22 26/18639 0.0384615384615385 32.5856643356643 0.0302598120477013 0.0857299340967153 GO:0015252 proton channel activity 1/22 27/18639 0.037037037037037 31.3787878787879 0.0314060154611729 0.0857299340967153 GO:0035255 ionotropic glutamate receptor binding 1/22 27/18639 0.037037037037037 31.3787878787879 0.0314060154611729 0.0857299340967153 GO:0016417 S-acyltransferase activity 1/22 29/18639 0.0344827586206897 29.2147335423197 0.0336945438791152 0.0871384498745752 GO:0015215 nucleotide transmembrane transporter activity 1/22 30/18639 0.0333333333333333 28.2409090909091 0.0348368716617407 0.0871384498745752 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/22 31/18639 0.032258064516129 27.3299120234604 0.035977910343209 0.0871384498745752 GO:0072349 modified amino acid transmembrane transporter activity 1/22 31/18639 0.032258064516129 27.3299120234604 0.035977910343209 0.0871384498745752 GO:0003713 transcription coactivator activity 2/22 256/18639 0.0078125 6.61896306818182 0.036235791036952 0.0871384498745752 GO:0042910 xenobiotic transmembrane transporter activity 1/22 32/18639 0.03125 26.4758522727273 0.0371176613090544 0.0871833440049882 GO:0051427 hormone receptor binding 1/22 34/18639 0.0294117647058824 24.918449197861 0.0393933056289408 0.0876676121545384 GO:0090482 vitamin transmembrane transporter activity 1/22 34/18639 0.0294117647058824 24.918449197861 0.0393933056289408 0.0876676121545384 GO:0005154 epidermal growth factor receptor binding 1/22 35/18639 0.0285714285714286 24.2064935064935 0.0405292017469824 0.0876676121545384 GO:0016409 palmitoyltransferase activity 1/22 36/18639 0.0277777777777778 23.5340909090909 0.0416638156774044 0.0876676121545384 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/22 36/18639 0.0277777777777778 23.5340909090909 0.0416638156774044 0.0876676121545384 GO:0030551 cyclic nucleotide binding 1/22 37/18639 0.027027027027027 22.8980343980344 0.0427971487986806 0.0882145311972804 GO:0042887 amide transmembrane transporter activity 1/22 38/18639 0.0263157894736842 22.2954545454545 0.0439292024878765 0.0887369890255105 GO:0035254 glutamate receptor binding 1/22 49/18639 0.0204081632653061 17.2903525046382 0.0562977429873788 0.10941263376613 GO:0005006 epidermal growth factor receptor activity 1/22 50/18639 0.02 16.9445454545455 0.0574145503921275 0.10941263376613 GO:0015605 organophosphate ester transmembrane transporter activity 1/22 50/18639 0.02 16.9445454545455 0.0574145503921275 0.10941263376613 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/22 53/18639 0.0188679245283019 15.9854202401372 0.0607574080886079 0.113638855869433 GO:0004601 peroxidase activity 1/22 57/18639 0.0175438596491228 14.8636363636364 0.0651969517317653 0.117587359373362 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/22 57/18639 0.0175438596491228 14.8636363636364 0.0651969517317653 0.117587359373362 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/22 59/18639 0.0169491525423729 14.3597842835131 0.067409205045692 0.119173940681068 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/22 60/18639 0.0166666666666667 14.1204545454545 0.0685134567942924 0.119173940681068 GO:0016836 hydro-lyase activity 1/22 61/18639 0.0163934426229508 13.8889716840537 0.0696164603978516 0.119173940681068 GO:0019843 rRNA binding 1/22 65/18639 0.0153846153846154 13.0342657342657 0.0740160202146846 0.124593634028052 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/22 67/18639 0.0149253731343284 12.6451831750339 0.0762083461233379 0.126181032105855 GO:0097110 scaffold protein binding 1/22 70/18639 0.0142857142857143 12.1032467532468 0.0794875475574555 0.129180833048561 GO:0140299 molecular sensor activity 1/22 71/18639 0.0140845070422535 11.9327784891165 0.0805781433867263 0.129180833048561 GO:0019199 transmembrane receptor protein kinase activity 1/22 78/18639 0.0128205128205128 10.8618881118881 0.0881778521824473 0.138694159683579 GO:0016835 carbon-oxygen lyase activity 1/22 79/18639 0.0126582278481013 10.7243958573073 0.0892586176181449 0.138694159683579 GO:0016209 antioxidant activity 1/22 86/18639 0.0116279069767442 9.8514799154334 0.0967898096032013 0.148117738938232 GO:0072341 modified amino acid binding 1/22 91/18639 0.010989010989011 9.31018981018981 0.102132796565026 0.153961379896532 GO:0004867 serine-type endopeptidase inhibitor activity 1/22 95/18639 0.0105263157894737 8.91818181818182 0.106385450047747 0.158013683159154 GO:0003712 transcription coregulator activity 2/22 495/18639 0.00404040404040404 3.42314049586777 0.114792616193624 0.168029771529797 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/22 130/18639 0.00769230769230769 6.51713286713287 0.142784918711572 0.203225285325235 GO:0005179 hormone activity 1/22 132/18639 0.00757575757575758 6.41838842975207 0.144821553085163 0.203225285325235 GO:0015297 antiporter activity 1/22 135/18639 0.00740740740740741 6.27575757575758 0.147867846503777 0.203225285325235 GO:0002020 protease binding 1/22 136/18639 0.00735294117647059 6.22961229946524 0.148880973793926 0.203225285325235 GO:0016922 nuclear receptor binding 1/22 137/18639 0.0072992700729927 6.18414067684141 0.149892951234154 0.203225285325235 GO:0070851 growth factor receptor binding 1/22 139/18639 0.00719424460431655 6.09516023544801 0.151913461535356 0.203225285325235 GO:0004713 protein tyrosine kinase activity 1/22 140/18639 0.00714285714285714 6.05162337662338 0.152921996878395 0.203225285325235 GO:0019955 cytokine binding 1/22 144/18639 0.00694444444444444 5.88352272727273 0.15694470176479 0.205862530886283 GO:0008509 monoatomic anion transmembrane transporter activity 1/22 149/18639 0.00671140939597315 5.68608907870653 0.161947443380335 0.20832155857025 GO:0019842 vitamin binding 1/22 150/18639 0.00666666666666667 5.64818181818182 0.162944585416334 0.20832155857025 GO:0004866 endopeptidase inhibitor activity 1/22 161/18639 0.0062111801242236 5.26228119706381 0.173838667482658 0.219471317696856 GO:0016874 ligase activity 1/22 167/18639 0.00598802395209581 5.07321720195972 0.179723713590033 0.222570320068705 GO:0005201 extracellular matrix structural constituent 1/22 168/18639 0.00595238095238095 5.04301948051948 0.180700655897365 0.222570320068705 GO:0061135 endopeptidase regulator activity 1/22 184/18639 0.00543478260869565 4.60449604743083 0.196181492161159 0.233300382008947 GO:0031406 carboxylic acid binding 1/22 187/18639 0.0053475935828877 4.53062712688381 0.199052891348485 0.233300382008947 GO:0046943 carboxylic acid transmembrane transporter activity 1/22 188/18639 0.00531914893617021 4.50652804642166 0.200007846713233 0.233300382008947 GO:0005342 organic acid transmembrane transporter activity 1/22 189/18639 0.00529100529100529 4.48268398268398 0.200961715195826 0.233300382008947 GO:0043177 organic acid binding 1/22 189/18639 0.00529100529100529 4.48268398268398 0.200961715195826 0.233300382008947 GO:0016829 lyase activity 1/22 200/18639 0.005 4.23613636363636 0.211382870378925 0.242609885321266 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/22 229/18639 0.00436681222707424 3.69968241365621 0.238238601964019 0.270360660655797 GO:0033218 amide binding 1/22 247/18639 0.00404858299595142 3.43006993006993 0.254466164274006 0.284407919717373 GO:0140104 molecular carrier activity 1/22 249/18639 0.00401606425702811 3.40251916757941 0.256248719745356 0.284407919717373 GO:0008514 organic anion transmembrane transporter activity 1/22 269/18639 0.00371747211895911 3.1495437647854 0.273851945955331 0.30064181023357 GO:0005126 cytokine receptor binding 1/22 275/18639 0.00363636363636364 3.08082644628099 0.279054884961449 0.303059606248456 GO:0015291 secondary active transmembrane transporter activity 1/22 287/18639 0.00348432055749129 2.95201140323092 0.289354204716104 0.310901858258793 GO:0045296 cadherin binding 1/22 334/18639 0.0029940119760479 2.53660860097986 0.328357047044099 0.349095386857411 GO:0005261 monoatomic cation channel activity 1/22 341/18639 0.00293255131964809 2.48453745667822 0.333988167469008 0.351383384524685 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 1/22 349/18639 0.00286532951289398 2.42758530867413 0.340368549997788 0.354404366492543 GO:0019001 guanyl nucleotide binding 1/22 400/18639 0.0025 2.11806818181818 0.379692549830848 0.387363106393087 GO:0032561 guanyl ribonucleotide binding 1/22 400/18639 0.0025 2.11806818181818 0.379692549830848 0.387363106393087 GO:0005216 monoatomic ion channel activity 1/22 448/18639 0.00223214285714286 1.89113230519481 0.414651400480626 0.418797914485432 GO:0140297 DNA-binding transcription factor binding 1/22 488/18639 0.00204918032786885 1.73612146050671 0.442339293123471 0.442339293123471