category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	29/102	238/9376	11.2005272697314	RPL13A/RPS14/RPL28/RPS2/RPS16/RPL7/RPL27A/RPS19/RPS11/RPS20/RPS12/RPL10/RPL18A/RPL18/RPLP2/C5AR1/RPS8/UBA52/RPS5/RPLP1/F13A1/RPS9/RPL37A/RPL34/C1QB/C1QA/RPL8/CYBB/RPS28	16.7162054883648
Genetic Information Processing	Translation	hsa03010	Ribosome	25/102	222/9376	10.3515279985868	RPL13A/RPS14/RPL28/RPS2/RPS16/RPL7/RPL27A/RPS19/RPS11/RPS20/RPS12/RPL10/RPL18A/RACK1/RPL18/RPLP2/RPS8/UBA52/RPS5/RPLP1/RPS9/RPL37A/RPL34/RPL8/RPS28	14.7878756496812
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	17/102	205/9376	7.62276422764228	MT-CO3/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1/MT-ND3/MT-ND2/MT-ND5/MT-ND4L/COX4I1/COL1A1/MT-ND6/CTSD/MMP2/CYBB	10.0544902293773
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	13/102	138/9376	8.65927820403524	MT-CO3/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1/MT-ND3/MT-ND2/MT-ND5/MT-ND4L/COX4I1/MT-ND6	9.50584190276691
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	16/102	275/9376	5.34816399286987	MT-CO3/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1/MT-ND3/MT-ND2/MT-ND5/MT-ND4L/COX4I1/MT-ND6/C1QB/C1QA/CYBB	7.67502649457693
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	13/102	227/9376	5.26423080245314	MT-CO3/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1/MT-ND3/MT-ND2/MT-ND5/MT-ND4L/COX4I1/MT-ND6	6.8205437031032
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	14/102	268/9376	4.80187298800117	MT-CO3/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1/MT-ND3/MT-ND2/MT-ND5/MT-ND4L/COX4I1/MT-ND6/UBA52	6.62225146863398
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	13/102	235/9376	5.08502294534835	MT-CO3/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1/MT-ND3/MT-ND2/MT-ND5/MT-ND4L/COX4I1/MT-ND6	6.6509511073562
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	15/102	388/9376	3.55366889023651	MT-CO3/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1/MT-ND3/MT-ND2/MT-ND5/APOE/MT-ND4L/COX4I1/MT-ND6/CYBB	5.38767134094112
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	13/102	308/9376	3.87980646804176	MT-CO3/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1/MT-ND3/MT-ND2/MT-ND5/MT-ND4L/COX4I1/MT-ND6	5.38933380284627
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	7/102	100/9376	6.43450980392157	HLA-DRA/CD14/HLA-DRB5/CSF1R/CD4/CD24/HLA-DRB1	5.72970397693943
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	13/102	368/9376	3.24722932651321	MT-CO3/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1/MT-ND3/MT-ND2/MT-ND5/MT-ND4L/COX4I1/MT-ND6	4.61221233234001
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	15/102	480/9376	2.87254901960784	MT-CO3/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1/MT-ND3/MT-ND2/MT-ND5/MT-ND4L/COX4I1/MT-ND6/UBA52/CYBB	4.41680886040202
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	6/102	82/9376	6.72596843615495	CD74/HLA-DRA/HLA-DRB5/CD4/HLA-DRB1/CTSL	5.46143438255881
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	6/102	87/9376	6.3394185260311	MT-CO3/MT-CYB/MT-CO2/MT-CO1/COX4I1/ATP1B3	5.24712351216854
Human Diseases	Immune disease	hsa05310	Asthma	4/102	32/9376	11.4901960784314	HLA-DRA/FCER1G/HLA-DRB5/HLA-DRB1	6.23367790550906
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	6/102	99/9376	5.57100415923945	HLA-DRA/C5AR1/HLA-DRB5/C1QB/C1QA/HLA-DRB1	4.79487857659743
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	8/102	181/9376	4.06283176253927	CD74/HLA-DRA/CD14/FCER1G/HLA-DRB5/CTSD/MRC1/HLA-DRB1	4.36353778679417
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	7/102	149/9376	4.31846295565206	MT-ND4/MT-ND1/MT-ND3/MT-ND2/MT-ND5/MT-ND4L/MT-ND6	4.28205287944501
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	7/102	155/9376	4.15129664769133	HLA-DRA/CD14/HLA-DRB5/MRC1/HLA-DRB1/CYBB/CTSL	4.14875991988428
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	5/102	88/9376	5.22281639928699	C5AR1/F13A1/SERPINE2/C1QB/C1QA	4.17382859869791
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	4/102	54/9376	6.80900508351489	CGA/HLA-DRA/HLA-DRB5/HLA-DRB1	4.489482318332
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	5/102	95/9376	4.83797729618163	HLA-DRA/HLA-DRB5/CCL3/HLA-DRB1/CTSL	3.94292935479743
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	6/102	160/9376	3.44705882352941	HLA-DRA/HLA-DRB5/PTPRC/CD4/HLA-DRB1/VCAN	3.27405028901598
Human Diseases	Immune disease	hsa05330	Allograft rejection	3/102	39/9376	7.07088989441931	HLA-DRA/HLA-DRB5/HLA-DRB1	3.98412686195432
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	4/102	78/9376	4.71392659627954	HLA-DRA/HLA-DRB5/HLA-DRB1/CYBB	3.45412479788417
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	3/102	42/9376	6.56582633053221	FTL/SAT1/CYBB	3.79116403902152
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	3/102	44/9376	6.26737967914439	HLA-DRA/HLA-DRB5/HLA-DRB1	3.67270271006107
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	3/102	45/9376	6.1281045751634	HLA-DRA/HLA-DRB5/HLA-DRB1	3.61618977159995
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	4/102	89/9376	4.13130645516634	FN1/SPP1/COL1A1/LAMB2	3.11268399171083
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	3/102	50/9376	5.51529411764706	HLA-DRA/HLA-DRB5/HLA-DRB1	3.35718689845999
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	4/102	93/9376	3.95361585494413	HLA-DRA/HLA-DRB5/CD4/HLA-DRB1	3.00195023196466
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	3/102	52/9376	5.30316742081448	APOE/PLTP/APOC1	3.26317947716359
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	5/102	143/9376	3.21404086109968	HLA-DRA/HLA-DRB5/C1QB/C1QA/HLA-DRB1	2.79791431951065
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/102	101/9376	3.64045816346341	FN1/COL1A1/MMP2/CYBB	2.79791938208645
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	4/102	103/9376	3.56976965543499	COL1A1/COL14A1/ATP1B3/COL15A1	2.75014034509238
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	4/102	103/9376	3.56976965543499	FN1/COL1A1/CD14/LAMB2	2.75014034509238
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	5/102	157/9376	2.9274384913201	MT-CO3/MT-CYB/MT-CO2/MT-CO1/COX4I1	2.55411604127244
NA	NA	hsa04382	Cornified envelope formation	6/102	217/9376	2.54161019246408	KRT7/S100A10/KRT8/S100A9/S100A6/S100A8	2.40953139181226
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	4/102	109/9376	3.37326857348444	HLA-DRA/HLA-DRB5/CD4/HLA-DRB1	2.6136217414071
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	4/102	112/9376	3.28291316526611	HLA-DRA/HLA-DRB5/LAMB2/HLA-DRB1	2.54889126553292
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	3/102	66/9376	4.17825311942959	HLA-DRA/HLA-DRB5/HLA-DRB1	2.71730124331483
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	3/102	68/9376	4.05536332179931	CD14/SPI1/CSF1R	2.65180330880075
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	3/102	70/9376	3.93949579831933	HLA-DRA/HLA-DRB5/HLA-DRB1	2.58876434211194
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	6/102	233/9376	2.36707902044938	FN1/FBLN1/COL1A1/DCN/ATP1B3/VCAN	2.21604919622144
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/102	78/9376	3.53544494720965	CD14/C1QB/C1QA	2.35808194879246
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	2/102	38/9376	4.83797729618163	PTPRC/CD4	2.48610486325596
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	5/102	204/9376	2.25297962322184	FN1/COL1A1/DCN/MMP2/CTSL	1.89748891411673
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	4/102	144/9376	2.55337690631808	CD14/C5AR1/C1QB/C1QA	1.96998251160682
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	3/102	93/9376	2.9652118912081	FN1/LAMB2/GADD45G	1.99737155486777
NA	NA	hsa04518	Integrin signaling	4/102	154/9376	2.38757321110262	FN1/SPP1/COL1A1/LAMB2	1.82077334270799
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	4/102	157/9376	2.34195079305608	STAB1/CD24/C1QB/C1QA	1.77826585002737
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	3/102	100/9376	2.75764705882353	CCL3/CSF1R/CXCL14	1.85311973045479
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	5/102	224/9376	2.05182072829132	HLA-DRA/HLA-DRB5/SPI1/CD4/HLA-DRB1	1.67093635034043
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/102	103/9376	2.67732724157624	CCL3/C1QB/C1QA	1.79505789914875
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	2/102	50/9376	3.67686274509804	SAT1/AOC1	1.99028641383428
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	2/102	52/9376	3.53544494720965	CGA/HSD17B1	1.92267953070872
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	4/102	169/9376	2.17565842905209	VAMP8/UBA52/CTSD/CTSL	1.61740067853937
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	3/102	109/9376	2.52995143011333	SPP1/CD14/CCL3	1.68489751464165
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	4/102	180/9376	2.04270152505447	CD74/HLA-DRA/HLA-DRB5/HLA-DRB1	1.48132024491311
Organismal Systems	Digestive system	hsa04978	Mineral absorption	2/102	61/9376	3.01382192221151	FTL/ATP1B3	1.65480464169066
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/102	65/9376	2.82835595776772	CGA/SPP1	1.55121303164609
Organismal Systems	Immune system	hsa04611	Platelet activation	3/102	126/9376	2.18860877684407	VAMP8/COL1A1/FCER1G	1.40865784195004
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	4/102	201/9376	1.82928494780997	CD14/SPI1/CSF1R/GADD45G	1.24638138247965
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	4/102	203/9376	1.81126243600889	FN1/SPP1/COL1A1/LAMB2	1.22547898374405
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	4/102	205/9376	1.79359158297465	HLA-DRA/HLA-DRB5/HLA-DRB1/GADD45G	1.20480792353004
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/102	137/9376	2.01288106483469	CTSD/GADD45G/CTSL	1.25244432912889
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	2/102	75/9376	2.45124183006536	CGA/ATP1B3	1.32329836422399
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/102	142/9376	1.94200497100249	TYROBP/SPI1/CSF1R	1.1861909601032
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	6/102	362/9376	1.52356191095223	CSH1/FN1/SPP1/COL1A1/LAMB2/CSF1R	1.06540745380685
Metabolism	Metabolism of cofactors and vitamins	hsa00770	Pantothenate and CoA biosynthesis	1/102	21/9376	4.37721755368814	ENPP1	1.62479647307267
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/102	22/9376	4.17825311942959	AOC1	1.56514045796367
Organismal Systems	Excretory system	hsa04964	Proximal tubule bicarbonate reclamation	1/102	23/9376	3.99658994032396	ATP1B3	1.5089260157529
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	5/102	298/9376	1.54230819844716	CSH1/CCL3/CSF1R/CD4/CXCL14	0.997726232932771
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/102	28/9376	3.28291316526611	AKR1B1	1.26870670400711
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/102	93/9376	1.97680792747206	CGA/MMP2	0.992792877770882
Organismal Systems	Digestive system	hsa04970	Salivary secretion	2/102	93/9376	1.97680792747206	LYZ/ATP1B3	0.992792877770882
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/102	94/9376	1.95577805590321	S100A9/S100A8	0.97668018820086
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/102	30/9376	3.0640522875817	FOLR2	1.18746443762579
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	4/102	248/9376	1.48260594560405	S100A10/CD14/PTPRC/ANXA2	0.807760981637665
NA	NA	hsa04981	Folate transport and metabolism	1/102	31/9376	2.9652118912081	FOLR2	1.14935120552944
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	4/102	250/9376	1.47074509803922	VAMP8/CTSD/LAPTM5/CTSL	0.791166257511609
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	3/102	173/9376	1.59401564093846	HLA-DRA/HLA-DRB5/HLA-DRB1	0.827005502838023
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/102	32/9376	2.87254901960784	AKR1B1	1.11274063546937
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/102	33/9376	2.78550207961973	VAMP8	1.07752246686912
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	2/102	105/9376	1.75088702147526	CD14/GADD45G	0.811443218819136
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/102	35/9376	2.62633053221289	AKR1B1	1.01087703365112
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	1/102	36/9376	2.55337690631808	AKR1B1	0.979279887158532
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/102	36/9376	2.55337690631808	ENPP1	0.979279887158532
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/102	37/9376	2.48436671966084	GADD45G	0.948733118583049
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/102	38/9376	2.41898864809082	ENPP1	0.919170257321039
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/102	38/9376	2.41898864809082	ATP1B3	0.919170257321039
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/102	116/9376	1.58485463150778	MMP2/CYBB	0.664696838345012
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/102	41/9376	2.24198947871832	MMP2	0.835804802647989
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/102	42/9376	2.18860877684407	AOC1	0.809621174580506
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/102	44/9376	2.0891265597148	ARHGDIB	0.75939808996525
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	2/102	122/9376	1.50691096110575	PTPRC/CD4	0.591015714225368
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/102	125/9376	1.47074509803922	FCER1G/CTSD	0.555646586438861
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/102	46/9376	1.99829497016198	FTL	0.711785530505751
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/102	48/9376	1.91503267973856	ATP1B3	0.666522988864428
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/102	130/9376	1.41417797888386	COL1A1/MMP2	0.498693737423326
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	3/102	216/9376	1.27668845315904	CD14/CCL3/CYBB	0.431441932400334
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/102	50/9376	1.83843137254902	GYPC	0.623385929208569
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/102	133/9376	1.38227922748047	TYROBP/FCER1G	0.46564208153601
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/102	53/9376	1.73436921938587	ATP1B3	0.562246468631856
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/102	138/9376	1.33219664677465	FN1/CD4	0.412285429612085
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/102	139/9376	1.3226124982367	CTSD/MMP2	0.401860476505083
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/102	56/9376	1.64145658263305	CD14	0.50490015248253
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/102	142/9376	1.29466998066832	MMP2/CTSL	0.371054164300824
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/102	59/9376	1.55799268860086	ENPP1	0.450887966458403
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/102	59/9376	1.55799268860086	CGA	0.450887966458403
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/102	59/9376	1.55799268860086	GADD45G	0.450887966458403
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	4/102	333/9376	1.10416298651593	FN1/SPP1/COL1A1/LAMB2	0.20296981362762
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/102	63/9376	1.45907251789605	PTGDS	0.383406036507734
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/102	63/9376	1.45907251789605	GADD45G	0.383406036507734
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/102	65/9376	1.41417797888386	AKR1B1	0.351396715467757
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/102	66/9376	1.39275103980986	HSD17B1	0.335789142238007
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	2/102	158/9376	1.16356415984115	CDKN1C/GADD45G	0.217445546388803
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/102	69/9376	1.33219664677465	FCER1G	0.290447144450677
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/102	71/9376	1.29466998066832	CGA	0.261371998474993
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/102	168/9376	1.09430438842204	FTL/CYBB	0.129346912559723
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/102	73/9376	1.25919957023905	CD4	0.233150512806932
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/102	73/9376	1.25919957023905	GADD45G	0.233150512806932
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/102	73/9376	1.25919957023905	GADD45G	0.233150512806932
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/102	75/9376	1.22562091503268	GADD45G	0.205729866388993
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/102	76/9376	1.20949432404541	PLTP	0.192304639042822
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/102	76/9376	1.20949432404541	ATP1B3	0.192304639042822
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/102	76/9376	1.20949432404541	GADD45G	0.192304639042822
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/102	77/9376	1.19378660555131	GADD45G	0.179061893450129
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/102	77/9376	1.19378660555131	GADD45G	0.179061893450129
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/102	78/9376	1.17848164906988	FN1	0.165996250609027
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/102	85/9376	1.08143021914648	ENPP1	0.0790889873127914
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/102	86/9376	1.06885544915641	ATP1B3	0.0672716163258124
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/102	87/9376	1.05656975433852	GADD45G	0.0555919126062345
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	2/102	193/9376	0.952555115310373	CCL3/CXCL14	-0.0698438122311792
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/102	90/9376	1.02135076252723	ATP1B3	0.0213438364058217
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/102	90/9376	1.02135076252723	CD4	0.0213438364058217
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/102	195/9376	0.942785319255907	C5AR1/CYBB	-0.0846704697472431
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	3/102	300/9376	0.91921568627451	CD14/CSF1R/GADD45G	-0.149139472264207
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/102	98/9376	0.93797519007603	PTPRC	-0.0647296820971341
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/102	98/9376	0.93797519007603	ATP1B3	-0.0647296820971341
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/102	99/9376	0.928500693206576	MMP2	-0.0750011337645336
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/102	102/9376	0.901191849288735	ATP1B3	-0.105223196198449
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/102	105/9376	0.875443510737628	UBA52	-0.134601498869028
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/102	105/9376	0.875443510737628	FCER1G	-0.134601498869028
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/102	106/9376	0.867184609692934	FOLR2	-0.144216066751264
NA	NA	hsa04081	Hormone signaling	2/102	219/9376	0.83946638015937	CSH1/CGA	-0.252094648929929
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/102	110/9376	0.835650623885918	CYBB	-0.181832049032784
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/102	110/9376	0.835650623885918	DCN	-0.181832049032784
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/102	226/9376	0.813465209092487	CGA/ATP1B3	-0.297684139017922
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/102	120/9376	0.766013071895425	ARHGDIB	-0.270534542147361
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/102	122/9376	0.753455480552877	ATP1B3	-0.287450255428572
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/102	122/9376	0.753455480552877	CSH1	-0.287450255428572
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/102	128/9376	0.718137254901961	ENPP1	-0.336721563922696
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	2/102	250/9376	0.735372549019608	DAB2/FOLR2	-0.444750908504527
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/102	253/9376	0.726652716422537	CD14/UBA52	-0.4622302499937
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/102	133/9376	0.691139613740233	GADD45G	-0.376212942853044
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	3/102	370/9376	0.745310015898251	CSH1/CGA/C5AR1	-0.524202315921116
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/102	136/9376	0.675893886966551	RACK1	-0.399275690398525
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/102	140/9376	0.656582633053221	SPP1	-0.429335191647276
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/102	142/9376	0.647334990334162	UBA52	-0.444082631501548
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/102	148/9376	0.621091679915209	GADD45G	-0.487262943841927
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/102	149/9376	0.616923279378866	FCER1G	-0.494311612486197
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/102	150/9376	0.61281045751634	GADD45G	-0.501319619909829
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/102	154/9376	0.596893302775656	ATP1B3	-0.528956542761379
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/102	157/9376	0.585487698264019	GADD45G	-0.549284723707849
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/102	166/9376	0.553744389321994	ATP1B3	-0.608359223184327
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/102	168/9376	0.547152194211018	CSH1	-0.62112131278679
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/102	170/9376	0.540715109573241	GADD45G	-0.633757791908184
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/102	178/9376	0.516413306895792	SERPINF1	-0.68310870341819
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/102	187/9376	0.491559190521128	CYBB	-0.736511033492282
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/102	196/9376	0.468987595038015	UBA52	-0.787886284057949
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/102	212/9376	0.433592304846467	CSF1R	-0.874795848817745
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/102	214/9376	0.429540040315191	CD4	-0.885297194925932
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/102	227/9376	0.404940830957934	CCL3	-0.951784098095447
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	1/102	232/9376	0.396213657876944	FN1	-0.976587917776663
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/102	238/9376	0.386225078266601	CSF1R	-1.00582915412084
NA	NA	hsa04519	Cadherin signaling	2/102	404/9376	0.455057270432926	KRT7/KRT8	-1.17421896688204