ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 76/1236 175/18639 0.434285714285714 6.54907073509015 3.53123216599285e-43 4.00794850840188e-40 GO:0015078 proton transmembrane transporter activity 42/1236 185/18639 0.227027027027027 3.4235896090265 1.19568167342077e-12 6.78549349666286e-10 GO:0009055 electron transfer activity 29/1236 116/18639 0.25 3.77002427184466 3.23142039942078e-10 1.2225540511142e-07 GO:0045296 cadherin binding 54/1236 334/18639 0.161676646706587 2.43809952909715 9.36226957468385e-10 2.65654399181654e-07 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 21/1236 68/18639 0.308823529411765 4.65708880639635 1.40568491400688e-09 3.19090475479561e-07 GO:0023023 MHC protein complex binding 14/1236 37/18639 0.378378378378378 5.70598268171084 4.2543810283437e-08 8.04787077861682e-06 GO:0022853 active monoatomic ion transmembrane transporter activity 25/1236 118/18639 0.211864406779661 3.19493582359717 1.8047069429851e-07 2.92620340041155e-05 GO:0023026 MHC class II protein complex binding 11/1236 27/18639 0.407407407407407 6.14374325782093 5.05856428176877e-07 7.17683807475945e-05 GO:0019843 rRNA binding 16/1236 65/18639 0.246153846153846 3.71202389843167 3.71683391794351e-06 0.000468734055207321 GO:0015399 primary active transmembrane transporter activity 28/1236 166/18639 0.168674698795181 2.54363083401567 4.40818983529208e-06 0.000500329546305652 GO:0044389 ubiquitin-like protein ligase binding 43/1236 322/18639 0.133540372670807 2.0138017849605 9.1197624661164e-06 0.000940993672640193 GO:0031625 ubiquitin protein ligase binding 40/1236 302/18639 0.132450331125828 1.99736385263293 2.24192439249403e-05 0.00212048682123394 GO:1990948 ubiquitin ligase inhibitor activity 6/1236 11/18639 0.545454545454545 8.22550750220653 2.90487120530453e-05 0.00238125733357613 GO:0002020 protease binding 23/1236 136/18639 0.169117647058824 2.55031053683609 2.9372337154243e-05 0.00238125733357613 GO:0043021 ribonucleoprotein complex binding 27/1236 177/18639 0.152542372881356 2.30035379298996 4.19331730492029e-05 0.00317294342738968 GO:0008137 NADH dehydrogenase (ubiquinone) activity 11/1236 41/18639 0.268292682926829 4.04587970636988 5.17977532293897e-05 0.00367440311970983 GO:0016651 oxidoreductase activity, acting on NAD(P)H 17/1236 88/18639 0.193181818181818 2.91320057369815 5.69477305825278e-05 0.00380209848300994 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 13/1236 58/18639 0.224137931034483 3.38002176096418 8.58510197110674e-05 0.0054133837428923 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 7/1236 18/18639 0.388888888888889 5.86448220064725 9.21340064821953e-05 0.00550379459775219 GO:0003954 NADH dehydrogenase activity 11/1236 44/18639 0.25 3.77002427184466 0.00010462819739695 0.00593765020227688 GO:0042605 peptide antigen binding 11/1236 45/18639 0.244444444444444 3.68624595469256 0.000130259701775469 0.007040226738817 GO:0032395 MHC class II receptor activity 5/1236 10/18639 0.5 7.54004854368932 0.000241851999993329 0.0123258322815896 GO:0055105 ubiquitin-protein transferase inhibitor activity 6/1236 15/18639 0.4 6.03203883495146 0.000249774574869217 0.0123258322815896 GO:0008135 translation factor activity, RNA binding 15/1236 83/18639 0.180722891566265 2.72531875073108 0.000329278343692264 0.0155721216704466 GO:0180051 translation factor activity 15/1236 84/18639 0.178571428571429 2.69287447988904 0.0003766935035243 0.0171018850600032 GO:0042608 T cell receptor binding 5/1236 11/18639 0.454545454545455 6.85458958517211 0.0004191880732769 0.0176214245618252 GO:0070990 snRNP binding 5/1236 11/18639 0.454545454545455 6.85458958517211 0.0004191880732769 0.0176214245618252 GO:0005504 fatty acid binding 10/1236 47/18639 0.212765957446809 3.20853129518694 0.0008589467081359 0.0337807257208309 GO:0043130 ubiquitin binding 16/1236 100/18639 0.16 2.41281553398058 0.000863119864232684 0.0337807257208309 GO:0022804 active transmembrane transporter activity 48/1236 457/18639 0.105032822757112 1.58390516453868 0.00107523012747872 0.040679539822945 GO:0016504 peptidase activator activity 11/1236 57/18639 0.192982456140351 2.91019417475728 0.00113947528061017 0.0417194981771789 GO:0042169 SH2 domain binding 9/1236 41/18639 0.219512195121951 3.31026521430263 0.00122091716829271 0.0433044058128821 GO:0016004 phospholipase activator activity 6/1236 20/18639 0.3 4.52402912621359 0.00145170271333386 0.049929775140422 GO:0015252 proton channel activity 7/1236 27/18639 0.259259259259259 3.9096548004315 0.00151820049668884 0.0506811048159362 GO:0003743 translation initiation factor activity 10/1236 51/18639 0.196078431372549 2.95688178183895 0.00166556939959025 0.0540120362438552 GO:0004129 cytochrome-c oxidase activity 5/1236 15/18639 0.333333333333333 5.02669902912621 0.0021788791127092 0.0650796787611826 GO:0031386 protein tag activity 5/1236 15/18639 0.333333333333333 5.02669902912621 0.0021788791127092 0.0650796787611826 GO:0141047 molecular tag activity 5/1236 15/18639 0.333333333333333 5.02669902912621 0.0021788791127092 0.0650796787611826 GO:0005131 growth hormone receptor binding 4/1236 10/18639 0.4 6.03203883495146 0.00292334040031771 0.0829497838590149 GO:0031720 haptoglobin binding 4/1236 10/18639 0.4 6.03203883495146 0.00292334040031771 0.0829497838590149 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/1236 16/18639 0.3125 4.71253033980583 0.0029977861736533 0.0829874952950364 GO:0019903 protein phosphatase binding 19/1236 144/18639 0.131944444444444 1.98973503236246 0.00313153212974796 0.0846259277919984 GO:0019902 phosphatase binding 23/1236 190/18639 0.121052631578947 1.8254854368932 0.00377525512185882 0.0996491758909246 GO:0060229 lipase activator activity 6/1236 24/18639 0.25 3.77002427184466 0.00401289418773089 0.103009635619231 GO:0140104 molecular carrier activity 28/1236 249/18639 0.112449799196787 1.69575388934378 0.00435110981855987 0.103009635619231 GO:0019107 myristoyltransferase activity 4/1236 11/18639 0.363636363636364 5.48367166813769 0.00435428458719816 0.103009635619231 GO:0050786 RAGE receptor binding 4/1236 11/18639 0.363636363636364 5.48367166813769 0.00435428458719816 0.103009635619231 GO:0016741 transferase activity, transferring one-carbon groups 25/1236 215/18639 0.116279069767442 1.7534996613231 0.00443598830255722 0.103009635619231 GO:0060590 ATPase regulator activity 9/1236 49/18639 0.183673469387755 2.76981375074302 0.00444711202232804 0.103009635619231 GO:0004197 cysteine-type endopeptidase activity 13/1236 88/18639 0.147727272727273 2.22774161518094 0.00516921110637595 0.117123027612992 GO:0032393 MHC class I receptor activity 5/1236 18/18639 0.277777777777778 4.18891585760518 0.00526279683547366 0.117123027612992 GO:0033293 monocarboxylic acid binding 12/1236 79/18639 0.151898734177215 2.29064765884233 0.00564564067458926 0.123226964724208 GO:0032182 ubiquitin-like protein binding 16/1236 120/18639 0.133333333333333 2.01067961165049 0.00576549286805387 0.123468573683795 GO:0017166 vinculin binding 4/1236 12/18639 0.333333333333333 5.02669902912621 0.00619170510889063 0.126706068171099 GO:0097371 MDM2/MDM4 family protein binding 4/1236 12/18639 0.333333333333333 5.02669902912621 0.00619170510889063 0.126706068171099 GO:0048306 calcium-dependent protein binding 12/1236 80/18639 0.15 2.2620145631068 0.00625157693178992 0.126706068171099 GO:0004712 protein serine/threonine/tyrosine kinase activity 8/1236 43/18639 0.186046511627907 2.80559945811696 0.0066143686201253 0.131707164628811 GO:0055106 ubiquitin-protein transferase regulator activity 7/1236 36/18639 0.194444444444444 2.93224110032362 0.0084754366664874 0.158655283728693 GO:0032396 inhibitory MHC class I receptor activity 4/1236 13/18639 0.307692307692308 4.64002987303958 0.00847956180256757 0.158655283728693 GO:0035325 Toll-like receptor binding 4/1236 13/18639 0.307692307692308 4.64002987303958 0.00847956180256757 0.158655283728693 GO:0042288 MHC class I protein binding 5/1236 20/18639 0.25 3.77002427184466 0.00852684784797383 0.158655283728693 GO:0008168 methyltransferase activity 23/1236 204/18639 0.112745098039216 1.7002070245574 0.00887841510792958 0.162532276572582 GO:0008276 protein methyltransferase activity 13/1236 95/18639 0.136842105263158 2.06359223300971 0.00981497452801145 0.176825334750682 GO:0038024 cargo receptor activity 10/1236 65/18639 0.153846153846154 2.32001493651979 0.0100963483707901 0.179052428138231 GO:0016209 antioxidant activity 12/1236 86/18639 0.13953488372093 2.10419959358772 0.0110412422587739 0.187879744245021 GO:0005344 oxygen carrier activity 4/1236 14/18639 0.285714285714286 4.30859916782247 0.0112570488168896 0.187879744245021 GO:0008474 palmitoyl-(protein) hydrolase activity 4/1236 14/18639 0.285714285714286 4.30859916782247 0.0112570488168896 0.187879744245021 GO:0098599 palmitoyl hydrolase activity 4/1236 14/18639 0.285714285714286 4.30859916782247 0.0112570488168896 0.187879744245021 GO:0043531 ADP binding 7/1236 38/18639 0.184210526315789 2.77791262135922 0.0114217641875828 0.187879744245021 GO:0004601 peroxidase activity 9/1236 57/18639 0.157894736842105 2.38106796116505 0.0121388917086536 0.196823458418884 GO:0042393 histone binding 26/1236 247/18639 0.105263157894737 1.5873786407767 0.0132816551838715 0.212319417375974 GO:0000774 adenyl-nucleotide exchange factor activity 4/1236 15/18639 0.266666666666667 4.02135922330097 0.0145582014365915 0.22511884206251 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 19/1236 167/18639 0.11377245508982 1.71569966862392 0.0149520760715646 0.22511884206251 GO:0004177 aminopeptidase activity 7/1236 40/18639 0.175 2.63901699029126 0.0150452446615053 0.22511884206251 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 7/1236 40/18639 0.175 2.63901699029126 0.0150452446615053 0.22511884206251 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 9/1236 59/18639 0.152542372881356 2.30035379298996 0.0150740370015425 0.22511884206251 GO:0140375 immune receptor activity 18/1236 156/18639 0.115384615384615 1.74001120238984 0.0153581036367245 0.226382436723147 GO:0042287 MHC protein binding 7/1236 41/18639 0.170731707317073 2.57465072223538 0.0171340113179094 0.246165858807939 GO:0140318 protein transporter activity 7/1236 41/18639 0.170731707317073 2.57465072223538 0.0171340113179094 0.246165858807939 GO:0019838 growth factor binding 16/1236 136/18639 0.117647058823529 1.77412906910337 0.0181622647393343 0.257677130989305 GO:0004708 MAP kinase kinase activity 4/1236 16/18639 0.25 3.77002427184466 0.0184116731909043 0.257990729279955 GO:0048027 mRNA 5'-UTR binding 5/1236 24/18639 0.208333333333333 3.14168689320388 0.0187660389995325 0.259749442249627 GO:0140030 modification-dependent protein binding 19/1236 173/18639 0.109826589595376 1.65619563387395 0.0209670735119255 0.286718414891993 GO:0001848 complement binding 5/1236 25/18639 0.2 3.01601941747573 0.0222104208073268 0.297978636857403 GO:0004029 aldehyde dehydrogenase (NAD+) activity 4/1236 17/18639 0.235294117647059 3.54825813820674 0.0228406532216688 0.297978636857403 GO:0008429 phosphatidylethanolamine binding 4/1236 17/18639 0.235294117647059 3.54825813820674 0.0228406532216688 0.297978636857403 GO:0032977 membrane insertase activity 4/1236 17/18639 0.235294117647059 3.54825813820674 0.0228406532216688 0.297978636857403 GO:0008239 dipeptidyl-peptidase activity 3/1236 10/18639 0.3 4.52402912621359 0.0245430153860404 0.306113433661053 GO:0016175 superoxide-generating NAD(P)H oxidase activity 3/1236 10/18639 0.3 4.52402912621359 0.0245430153860404 0.306113433661053 GO:0140940 histone H2A methyltransferase activity 3/1236 10/18639 0.3 4.52402912621359 0.0245430153860404 0.306113433661053 GO:1990259 histone H2AQ104 methyltransferase activity 3/1236 10/18639 0.3 4.52402912621359 0.0245430153860404 0.306113433661053 GO:0015485 cholesterol binding 8/1236 54/18639 0.148148148148148 2.23408845738943 0.0250422254610762 0.308674794746936 GO:0042277 peptide binding 25/1236 249/18639 0.100401606425703 1.51406597262838 0.0252922959572379 0.308674794746936 GO:0050750 low-density lipoprotein particle receptor binding 5/1236 26/18639 0.192307692307692 2.90001867064974 0.0260396999063208 0.314415525464618 GO:0061134 peptidase regulator activity 23/1236 226/18639 0.101769911504425 1.53470014606066 0.0269896648603046 0.319097172699787 GO:0160215 deacylase activity 9/1236 65/18639 0.138461538461538 2.08801344286781 0.0269897168098498 0.319097172699787 GO:0003746 translation elongation factor activity 4/1236 18/18639 0.222222222222222 3.35113268608414 0.0278628979034388 0.319438273943465 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 4/1236 18/18639 0.222222222222222 3.35113268608414 0.0278628979034388 0.319438273943465 GO:0035615 clathrin adaptor activity 4/1236 18/18639 0.222222222222222 3.35113268608414 0.0278628979034388 0.319438273943465 GO:0001671 ATPase activator activity 5/1236 27/18639 0.185185185185185 2.79261057173679 0.0302659097444266 0.343518075599242 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 7/1236 46/18639 0.152173913043478 2.29479738286197 0.0306824653364871 0.344798001553593 GO:0008199 ferric iron binding 3/1236 11/18639 0.272727272727273 4.11275375110327 0.0321137894356062 0.347292536618637 GO:0019864 IgG binding 3/1236 11/18639 0.272727272727273 4.11275375110327 0.0321137894356062 0.347292536618637 GO:0048407 platelet-derived growth factor binding 3/1236 11/18639 0.272727272727273 4.11275375110327 0.0321137894356062 0.347292536618637 GO:0042054 histone methyltransferase activity 9/1236 67/18639 0.134328358208955 2.02568468337922 0.032128384444896 0.347292536618637 GO:0043394 proteoglycan binding 6/1236 37/18639 0.162162162162162 2.44542114930464 0.0333565626067456 0.35196407023807 GO:0070003 threonine-type peptidase activity 4/1236 19/18639 0.210526315789474 3.1747572815534 0.0334908542605388 0.35196407023807 GO:0097001 ceramide binding 4/1236 19/18639 0.210526315789474 3.1747572815534 0.0334908542605388 0.35196407023807 GO:0140938 histone H3 methyltransferase activity 7/1236 47/18639 0.148936170212766 2.24597190663086 0.0340643650693269 0.354041342893949 GO:0097718 disordered domain specific binding 5/1236 28/18639 0.178571428571429 2.69287447988904 0.0348989780227117 0.354041342893949 GO:0030145 manganese ion binding 9/1236 68/18639 0.132352941176471 1.99589520274129 0.0349362382415175 0.354041342893949 GO:0032934 sterol binding 9/1236 68/18639 0.132352941176471 1.99589520274129 0.0349362382415175 0.354041342893949 GO:0008238 exopeptidase activity 12/1236 102/18639 0.117647058823529 1.77412906910337 0.0373911098770042 0.370716703848989 GO:0042162 telomeric DNA binding 6/1236 38/18639 0.157894736842105 2.38106796116505 0.0374693373103387 0.370716703848989 GO:0002039 p53 binding 9/1236 69/18639 0.130434782608696 1.96696918531026 0.0379082199198556 0.370716703848989 GO:0000339 RNA cap binding 4/1236 20/18639 0.2 3.01601941747573 0.03973185586368 0.370716703848989 GO:0003785 actin monomer binding 5/1236 29/18639 0.172413793103448 2.60001673920321 0.0399467014724292 0.370716703848989 GO:0043236 laminin binding 5/1236 29/18639 0.172413793103448 2.60001673920321 0.0399467014724292 0.370716703848989 GO:0016273 arginine N-methyltransferase activity 3/1236 12/18639 0.25 3.77002427184466 0.0407544842111781 0.370716703848989 GO:0016274 protein-arginine N-methyltransferase activity 3/1236 12/18639 0.25 3.77002427184466 0.0407544842111781 0.370716703848989 GO:0016423 tRNA (guanine) methyltransferase activity 3/1236 12/18639 0.25 3.77002427184466 0.0407544842111781 0.370716703848989 GO:0036009 protein-glutamine N-methyltransferase activity 3/1236 12/18639 0.25 3.77002427184466 0.0407544842111781 0.370716703848989 GO:0097110 scaffold protein binding 9/1236 70/18639 0.128571428571429 1.93886962552011 0.0410478443794298 0.370716703848989 GO:0017124 SH3 domain binding 13/1236 115/18639 0.11304347826087 1.70470662726889 0.0411544534669362 0.370716703848989 GO:0035401 histone H3Y41 kinase activity 13/1236 115/18639 0.11304347826087 1.70470662726889 0.0411544534669362 0.370716703848989 GO:0140801 histone H2AXY142 kinase activity 13/1236 115/18639 0.11304347826087 1.70470662726889 0.0411544534669362 0.370716703848989 GO:0042826 histone deacetylase binding 14/1236 127/18639 0.110236220472441 1.66237290727009 0.0419918128559097 0.374897744177223 GO:0019207 kinase regulator activity 27/1236 287/18639 0.0940766550522648 1.41868509184398 0.0422792169644797 0.374897744177223 GO:0003779 actin binding 39/1236 443/18639 0.0880361173814898 1.32759319730873 0.0431696391811122 0.377850854903404 GO:0001098 basal transcription machinery binding 8/1236 60/18639 0.133333333333333 2.01067961165049 0.0436109797289391 0.377850854903404 GO:0001099 basal RNA polymerase II transcription machinery binding 8/1236 60/18639 0.133333333333333 2.01067961165049 0.0436109797289391 0.377850854903404 GO:0004713 protein tyrosine kinase activity 15/1236 140/18639 0.107142857142857 1.61572468793343 0.044784166511959 0.385075977205102 GO:0001846 opsonin binding 4/1236 21/18639 0.19047619047619 2.87239944521498 0.0465883746552886 0.391687446175945 GO:0009931 calcium-dependent protein serine/threonine kinase activity 4/1236 21/18639 0.19047619047619 2.87239944521498 0.0465883746552886 0.391687446175945 GO:0140312 cargo adaptor activity 4/1236 21/18639 0.19047619047619 2.87239944521498 0.0465883746552886 0.391687446175945 GO:0043560 insulin receptor substrate binding 3/1236 13/18639 0.230769230769231 3.48002240477969 0.0504369609337613 0.420834596931727 GO:0004527 exonuclease activity 10/1236 84/18639 0.119047619047619 1.79524965325936 0.0507967751362525 0.420834596931727 GO:0070325 lipoprotein particle receptor binding 5/1236 31/18639 0.161290322580645 2.43227372377075 0.0513066618115348 0.421196012306115 GO:0016874 ligase activity 17/1236 167/18639 0.101796407185629 1.53509970350561 0.0515825953396917 0.421196012306115 GO:0031072 heat shock protein binding 14/1236 131/18639 0.106870229007634 1.6116134291855 0.052190164018672 0.423113115437091 GO:0004407 histone deacetylase activity 4/1236 22/18639 0.181818181818182 2.74183583406884 0.0540583145877585 0.426084632341013 GO:0033558 protein lysine deacetylase activity 4/1236 22/18639 0.181818181818182 2.74183583406884 0.0540583145877585 0.426084632341013 GO:0061133 endopeptidase activator activity 4/1236 22/18639 0.181818181818182 2.74183583406884 0.0540583145877585 0.426084632341013 GO:0140035 ubiquitin-like protein reader activity 4/1236 22/18639 0.181818181818182 2.74183583406884 0.0540583145877585 0.426084632341013 GO:0005080 protein kinase C binding 7/1236 52/18639 0.134615384615385 2.03001306945482 0.0546445303316047 0.427734771906009 GO:0048029 monosaccharide binding 9/1236 74/18639 0.121621621621622 1.83406586197848 0.0553432405657408 0.430236835904903 GO:0043175 RNA polymerase core enzyme binding 6/1236 42/18639 0.142857142857143 2.15429958391123 0.0570640289544816 0.440596414036303 GO:0031369 translation initiation factor binding 5/1236 32/18639 0.15625 2.35626516990291 0.057623934874706 0.441913284343184 GO:0140296 general transcription initiation factor binding 7/1236 53/18639 0.132075471698113 1.99171093606888 0.0595207349661672 0.45207439318153 GO:0003712 transcription coregulator activity 42/1236 495/18639 0.0848484848484849 1.27952338923213 0.0599451089422176 0.45207439318153 GO:0044548 S100 protein binding 3/1236 14/18639 0.214285714285714 3.23144937586685 0.0611223915110899 0.45207439318153 GO:0004602 glutathione peroxidase activity 4/1236 23/18639 0.173913043478261 2.62262558041368 0.0621353350980782 0.45207439318153 GO:0005158 insulin receptor binding 4/1236 23/18639 0.173913043478261 2.62262558041368 0.0621353350980782 0.45207439318153 GO:0017134 fibroblast growth factor binding 4/1236 23/18639 0.173913043478261 2.62262558041368 0.0621353350980782 0.45207439318153 GO:0043274 phospholipase binding 4/1236 23/18639 0.173913043478261 2.62262558041368 0.0621353350980782 0.45207439318153 GO:0070577 lysine-acetylated histone binding 4/1236 23/18639 0.173913043478261 2.62262558041368 0.0621353350980782 0.45207439318153 GO:0071889 14-3-3 protein binding 5/1236 33/18639 0.151515151515152 2.28486319505737 0.0643660326563803 0.458750203739238 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 7/1236 54/18639 0.12962962962963 1.95482740021575 0.0646558321264999 0.458750203739238 GO:0017069 snRNA binding 7/1236 54/18639 0.12962962962963 1.95482740021575 0.0646558321264999 0.458750203739238 GO:0120013 lipid transfer activity 8/1236 65/18639 0.123076923076923 1.85601194921583 0.064669632245179 0.458750203739238 GO:0043022 ribosome binding 12/1236 112/18639 0.107142857142857 1.61572468793343 0.0675602929400703 0.469241496015488 GO:0016790 thiolester hydrolase activity 6/1236 44/18639 0.136363636363636 2.05637687555163 0.0687890890348298 0.469241496015488 GO:0015295 solute:proton symporter activity 4/1236 24/18639 0.166666666666667 2.51334951456311 0.0708091943177873 0.469241496015488 GO:0042625 ATPase-coupled ion transmembrane transporter activity 4/1236 24/18639 0.166666666666667 2.51334951456311 0.0708091943177873 0.469241496015488 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 4/1236 24/18639 0.166666666666667 2.51334951456311 0.0708091943177873 0.469241496015488 GO:0046961 proton-transporting ATPase activity, rotational mechanism 4/1236 24/18639 0.166666666666667 2.51334951456311 0.0708091943177873 0.469241496015488 GO:0070300 phosphatidic acid binding 4/1236 24/18639 0.166666666666667 2.51334951456311 0.0708091943177873 0.469241496015488 GO:0140033 acetylation-dependent protein binding 4/1236 24/18639 0.166666666666667 2.51334951456311 0.0708091943177873 0.469241496015488 GO:0008175 tRNA methyltransferase activity 5/1236 34/18639 0.147058823529412 2.21766133637921 0.0715304814911414 0.469241496015488 GO:0031406 carboxylic acid binding 18/1236 187/18639 0.0962566844919786 1.45156014744821 0.0715746127529453 0.469241496015488 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/1236 15/18639 0.2 3.01601941747573 0.0727634390297145 0.469241496015488 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/1236 15/18639 0.2 3.01601941747573 0.0727634390297145 0.469241496015488 GO:0005041 low-density lipoprotein particle receptor activity 3/1236 15/18639 0.2 3.01601941747573 0.0727634390297145 0.469241496015488 GO:0015556 C4-dicarboxylate transmembrane transporter activity 3/1236 15/18639 0.2 3.01601941747573 0.0727634390297145 0.469241496015488 GO:0141050 histone H3K deacetylase activity 3/1236 15/18639 0.2 3.01601941747573 0.0727634390297145 0.469241496015488 GO:0141051 histone H4K deacetylase activity 3/1236 15/18639 0.2 3.01601941747573 0.0727634390297145 0.469241496015488 GO:0140597 protein carrier chaperone 18/1236 188/18639 0.0957446808510638 1.44383908283413 0.0744916114287911 0.477672197580101 GO:0043177 organic acid binding 18/1236 189/18639 0.0952380952380952 1.43619972260749 0.0774869019352407 0.493886019229283 GO:0000175 3'-5'-RNA exonuclease activity 5/1236 35/18639 0.142857142857143 2.15429958391123 0.0791129495693907 0.493886019229283 GO:0017025 TBP-class protein binding 4/1236 25/18639 0.16 2.41281553398058 0.0800661035578749 0.493886019229283 GO:0019706 protein-cysteine S-palmitoyltransferase activity 4/1236 25/18639 0.16 2.41281553398058 0.0800661035578749 0.493886019229283 GO:0019707 protein-cysteine S-acyltransferase activity 4/1236 25/18639 0.16 2.41281553398058 0.0800661035578749 0.493886019229283 GO:0047617 fatty acyl-CoA hydrolase activity 4/1236 25/18639 0.16 2.41281553398058 0.0800661035578749 0.493886019229283 GO:0120020 cholesterol transfer activity 4/1236 25/18639 0.16 2.41281553398058 0.0800661035578749 0.493886019229283 GO:0000049 tRNA binding 9/1236 80/18639 0.1125 1.6965109223301 0.0822282867551582 0.504481651173538 GO:0043178 alcohol binding 10/1236 92/18639 0.108695652173913 1.63914098775855 0.0833199559554187 0.507487951856538 GO:0106310 protein serine kinase activity 31/1236 361/18639 0.0858725761772853 1.29496678589678 0.0841909264115865 0.507487951856538 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/1236 16/18639 0.1875 2.82751820388349 0.085306154223286 0.507487951856538 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 3/1236 16/18639 0.1875 2.82751820388349 0.085306154223286 0.507487951856538 GO:0016279 protein-lysine N-methyltransferase activity 8/1236 69/18639 0.115942028985507 1.74841705360912 0.0853860914298657 0.507487951856538 GO:0003713 transcription coactivator activity 23/1236 256/18639 0.08984375 1.35485247269417 0.0854010562155056 0.507487951856538 GO:0000993 RNA polymerase II complex binding 5/1236 36/18639 0.138888888888889 2.09445792880259 0.0871073413882154 0.512263380702717 GO:0016409 palmitoyltransferase activity 5/1236 36/18639 0.138888888888889 2.09445792880259 0.0871073413882154 0.512263380702717 GO:0020037 heme binding 14/1236 142/18639 0.0985915492957746 1.48677013537536 0.0886231447107839 0.515273296239255 GO:0008157 protein phosphatase 1 binding 4/1236 26/18639 0.153846153846154 2.32001493651979 0.0898890860399758 0.515273296239255 GO:0016289 acyl-CoA hydrolase activity 4/1236 26/18639 0.153846153846154 2.32001493651979 0.0898890860399758 0.515273296239255 GO:0051139 metal cation:proton antiporter activity 4/1236 26/18639 0.153846153846154 2.32001493651979 0.0898890860399758 0.515273296239255 GO:0070006 metalloaminopeptidase activity 4/1236 26/18639 0.153846153846154 2.32001493651979 0.0898890860399758 0.515273296239255 GO:0016278 lysine N-methyltransferase activity 8/1236 70/18639 0.114285714285714 1.72343966712899 0.0911071555654057 0.51963126415445 GO:0004175 endopeptidase activity 34/1236 405/18639 0.0839506172839506 1.26598345918734 0.0929944938139593 0.527743752394219 GO:0019213 deacetylase activity 5/1236 37/18639 0.135135135135135 2.03785095775387 0.09550590057282 0.538533592554438 GO:0140297 DNA-binding transcription factor binding 40/1236 488/18639 0.0819672131147541 1.23607353175235 0.0967278813956293 0.538533592554438 GO:0033218 amide binding 22/1236 247/18639 0.0890688259109312 1.34316654219567 0.0973362279930848 0.538533592554438 GO:0001540 amyloid-beta binding 9/1236 83/18639 0.108433734939759 1.63519125043865 0.0981757617054782 0.538533592554438 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/1236 17/18639 0.176470588235294 2.66119360365505 0.0986916187236327 0.538533592554438 GO:0019198 transmembrane receptor protein phosphatase activity 3/1236 17/18639 0.176470588235294 2.66119360365505 0.0986916187236327 0.538533592554438 GO:0036041 long-chain fatty acid binding 3/1236 17/18639 0.176470588235294 2.66119360365505 0.0986916187236327 0.538533592554438 GO:0048038 quinone binding 3/1236 17/18639 0.176470588235294 2.66119360365505 0.0986916187236327 0.538533592554438 GO:0004364 glutathione transferase activity 4/1236 27/18639 0.148148148148148 2.23408845738943 0.100258334091376 0.54284075667901 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 7/1236 60/18639 0.116666666666667 1.75934466019417 0.100909331854217 0.54284075667901 GO:0004518 nuclease activity 19/1236 209/18639 0.0909090909090909 1.37091791703442 0.100915770624909 0.54284075667901 GO:0005496 steroid binding 11/1236 108/18639 0.101851851851852 1.53593581445523 0.102345429994802 0.547934259641984 GO:0000146 microfilament motor activity 5/1236 38/18639 0.131578947368421 1.98422330097087 0.104299319248954 0.553176296016646 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 5/1236 38/18639 0.131578947368421 1.98422330097087 0.104299319248954 0.553176296016646 GO:0003697 single-stranded DNA binding 12/1236 121/18639 0.0991735537190083 1.49554681858301 0.105468788837827 0.554199422828397 GO:0051082 unfolded protein binding 12/1236 121/18639 0.0991735537190083 1.49554681858301 0.105468788837827 0.554199422828397 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 7/1236 61/18639 0.114754098360656 1.73050294445329 0.107845562988946 0.56199241184279 GO:0140996 histone H3 kinase activity 30/1236 357/18639 0.0840336134453782 1.26723504935955 0.107942154873769 0.56199241184279 GO:0003689 DNA clamp loader activity 15/1236 160/18639 0.09375 1.41375910194175 0.110595654367319 0.564286814438357 GO:0016866 intramolecular transferase activity 4/1236 28/18639 0.142857142857143 2.15429958391123 0.11115156010282 0.564286814438357 GO:0046625 sphingolipid binding 4/1236 28/18639 0.142857142857143 2.15429958391123 0.11115156010282 0.564286814438357 GO:0008409 5'-3' exonuclease activity 3/1236 18/18639 0.166666666666667 2.51334951456311 0.112857362887671 0.564286814438357 GO:0030228 lipoprotein particle receptor activity 3/1236 18/18639 0.166666666666667 2.51334951456311 0.112857362887671 0.564286814438357 GO:0070064 proline-rich region binding 3/1236 18/18639 0.166666666666667 2.51334951456311 0.112857362887671 0.564286814438357 GO:0098641 cadherin binding involved in cell-cell adhesion 3/1236 18/18639 0.166666666666667 2.51334951456311 0.112857362887671 0.564286814438357 GO:1901611 phosphatidylglycerol binding 3/1236 18/18639 0.166666666666667 2.51334951456311 0.112857362887671 0.564286814438357 GO:1990381 ubiquitin-specific protease binding 3/1236 18/18639 0.166666666666667 2.51334951456311 0.112857362887671 0.564286814438357 GO:0008234 cysteine-type peptidase activity 17/1236 187/18639 0.0909090909090909 1.37091791703442 0.11572921453039 0.574586804067675 GO:0031491 nucleosome binding 8/1236 74/18639 0.108108108108108 1.6302807662031 0.116126646016987 0.574586804067675 GO:0035173 histone kinase activity 30/1236 360/18639 0.0833333333333333 1.25667475728155 0.116436092454242 0.574586804067675 GO:0016417 S-acyltransferase activity 4/1236 29/18639 0.137931034482759 2.08001339136257 0.122544337483682 0.587975352898474 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 4/1236 29/18639 0.137931034482759 2.08001339136257 0.122544337483682 0.587975352898474 GO:0003725 double-stranded RNA binding 8/1236 75/18639 0.106666666666667 1.60854368932039 0.122904297111741 0.587975352898474 GO:0044183 protein folding chaperone 8/1236 75/18639 0.106666666666667 1.60854368932039 0.122904297111741 0.587975352898474 GO:0004532 RNA exonuclease activity 5/1236 40/18639 0.125 1.88501213592233 0.123026434908113 0.587975352898474 GO:0015036 disulfide oxidoreductase activity 5/1236 40/18639 0.125 1.88501213592233 0.123026434908113 0.587975352898474 GO:0019887 protein kinase regulator activity 22/1236 255/18639 0.0862745098039216 1.30102798400914 0.124254265411386 0.587975352898474 GO:0046624 sphingolipid transporter activity 3/1236 19/18639 0.157894736842105 2.38106796116505 0.127738583255259 0.587975352898474 GO:0140036 ubiquitin-modified protein reader activity 3/1236 19/18639 0.157894736842105 2.38106796116505 0.127738583255259 0.587975352898474 GO:0046906 tetrapyrrole binding 14/1236 152/18639 0.0921052631578947 1.38895631067961 0.132948838028935 0.587975352898474 GO:0001965 G-protein alpha-subunit binding 4/1236 30/18639 0.133333333333333 2.01067961165049 0.134410428655538 0.587975352898474 GO:0031210 phosphatidylcholine binding 4/1236 30/18639 0.133333333333333 2.01067961165049 0.134410428655538 0.587975352898474 GO:0051721 protein phosphatase 2A binding 4/1236 30/18639 0.133333333333333 2.01067961165049 0.134410428655538 0.587975352898474 GO:1901505 carbohydrate derivative transmembrane transporter activity 6/1236 53/18639 0.113207547169811 1.70718080234475 0.137114975471812 0.587975352898474 GO:0001094 TFIID-class transcription factor complex binding 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0004090 carbonyl reductase (NADPH) activity 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0004382 GDP phosphatase activity 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0005381 iron ion transmembrane transporter activity 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0005522 profilin binding 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0008140 cAMP response element binding protein binding 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0016868 intramolecular phosphotransferase activity 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0043121 neurotrophin binding 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0045322 unmethylated CpG binding 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0047429 nucleoside triphosphate diphosphatase activity 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0051880 G-quadruplex DNA binding 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0070513 death domain binding 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0097177 mitochondrial ribosome binding 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0141109 transporter activator activity 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/1236 10/18639 0.2 3.01601941747573 0.13883470887823 0.587975352898474 GO:0141003 histone H2AX kinase activity 29/1236 354/18639 0.0819209039548023 1.23537518512424 0.139993175533372 0.589168557263117 GO:0019210 kinase inhibitor activity 9/1236 90/18639 0.1 1.50800970873786 0.141747574063487 0.589168557263117 GO:0016853 isomerase activity 16/1236 180/18639 0.0888888888888889 1.34045307443366 0.142369806978215 0.589168557263117 GO:0005506 iron ion binding 14/1236 154/18639 0.0909090909090909 1.37091791703442 0.14308541362595 0.589168557263117 GO:0031492 nucleosomal DNA binding 5/1236 42/18639 0.119047619047619 1.79524965325936 0.143187609393533 0.589168557263117 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 3/1236 20/18639 0.15 2.2620145631068 0.143269182206714 0.589168557263117 GO:0016505 peptidase activator activity involved in apoptotic process 3/1236 20/18639 0.15 2.2620145631068 0.143269182206714 0.589168557263117 GO:0140939 histone H4 methyltransferase activity 3/1236 20/18639 0.15 2.2620145631068 0.143269182206714 0.589168557263117 GO:0051287 NAD binding 6/1236 54/18639 0.111111111111111 1.67556634304207 0.146172368389976 0.596880218720395 GO:0005310 dicarboxylic acid transmembrane transporter activity 4/1236 31/18639 0.129032258064516 1.9458189790166 0.146722097817613 0.596880218720395 GO:0008327 methyl-CpG binding 4/1236 31/18639 0.129032258064516 1.9458189790166 0.146722097817613 0.596880218720395 GO:0072341 modified amino acid binding 9/1236 91/18639 0.0989010989010989 1.49143817347701 0.148668445761722 0.602307159626082 GO:1901681 sulfur compound binding 23/1236 275/18639 0.0836363636363636 1.26124448367167 0.149117455378792 0.602307159626082 GO:0008375 acetylglucosaminyltransferase activity 5/1236 43/18639 0.116279069767442 1.7534996613231 0.15376955171236 0.602628933565748 GO:0048156 tau protein binding 5/1236 43/18639 0.116279069767442 1.7534996613231 0.15376955171236 0.602628933565748 GO:0051015 actin filament binding 18/1236 209/18639 0.0861244019138756 1.29876434245366 0.154148679416292 0.602628933565748 GO:0008173 RNA methyltransferase activity 7/1236 67/18639 0.104477611940299 1.57553253151717 0.154498184284933 0.602628933565748 GO:0050840 extracellular matrix binding 7/1236 67/18639 0.104477611940299 1.57553253151717 0.154498184284933 0.602628933565748 GO:0140098 catalytic activity, acting on RNA 31/1236 387/18639 0.0801033591731266 1.20796643335591 0.158691063268698 0.602628933565748 GO:0008094 ATP-dependent activity, acting on DNA 18/1236 210/18639 0.0857142857142857 1.29257975034674 0.158809447319086 0.602628933565748 GO:0019200 carbohydrate kinase activity 3/1236 21/18639 0.142857142857143 2.15429958391123 0.159382650131951 0.602628933565748 GO:0051010 microtubule plus-end binding 3/1236 21/18639 0.142857142857143 2.15429958391123 0.159382650131951 0.602628933565748 GO:0072542 protein phosphatase activator activity 3/1236 21/18639 0.142857142857143 2.15429958391123 0.159382650131951 0.602628933565748 GO:0022884 macromolecule transmembrane transporter activity 4/1236 32/18639 0.125 1.88501213592233 0.159450406809456 0.602628933565748 GO:0030515 snoRNA binding 4/1236 32/18639 0.125 1.88501213592233 0.159450406809456 0.602628933565748 GO:0051059 NF-kappaB binding 4/1236 32/18639 0.125 1.88501213592233 0.159450406809456 0.602628933565748 GO:0120015 sterol transfer activity 4/1236 32/18639 0.125 1.88501213592233 0.159450406809456 0.602628933565748 GO:0061135 endopeptidase regulator activity 16/1236 184/18639 0.0869565217391304 1.31131279020684 0.162067647875276 0.602628933565748 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 2/1236 11/18639 0.181818181818182 2.74183583406884 0.162550468754369 0.602628933565748 GO:0001851 complement component C3b binding 2/1236 11/18639 0.181818181818182 2.74183583406884 0.162550468754369 0.602628933565748 GO:0005536 D-glucose binding 2/1236 11/18639 0.181818181818182 2.74183583406884 0.162550468754369 0.602628933565748 GO:0008432 JUN kinase binding 2/1236 11/18639 0.181818181818182 2.74183583406884 0.162550468754369 0.602628933565748 GO:0015217 ADP transmembrane transporter activity 2/1236 11/18639 0.181818181818182 2.74183583406884 0.162550468754369 0.602628933565748 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/1236 11/18639 0.181818181818182 2.74183583406884 0.162550468754369 0.602628933565748 GO:0034056 estrogen response element binding 2/1236 11/18639 0.181818181818182 2.74183583406884 0.162550468754369 0.602628933565748 GO:0034713 type I transforming growth factor beta receptor binding 2/1236 11/18639 0.181818181818182 2.74183583406884 0.162550468754369 0.602628933565748 GO:0050998 nitric-oxide synthase binding 2/1236 11/18639 0.181818181818182 2.74183583406884 0.162550468754369 0.602628933565748 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/1236 11/18639 0.181818181818182 2.74183583406884 0.162550468754369 0.602628933565748 GO:0051219 phosphoprotein binding 9/1236 93/18639 0.0967741935483871 1.45936423426245 0.163001834893995 0.602628933565748 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/1236 44/18639 0.113636363636364 1.71364739629303 0.164664482824864 0.606799311708509 GO:0008201 heparin binding 15/1236 172/18639 0.0872093023255814 1.31512474599232 0.168809827418066 0.620061987441763 GO:0019888 protein phosphatase regulator activity 10/1236 107/18639 0.0934579439252336 1.40935486797931 0.171796433034069 0.628996617721509 GO:0004674 protein serine/threonine kinase activity 34/1236 433/18639 0.0785219399538106 1.18411847799278 0.173723378480295 0.632197903501584 GO:0004715 non-membrane spanning protein tyrosine kinase activity 5/1236 45/18639 0.111111111111111 1.67556634304207 0.175855531075537 0.632197903501584 GO:0031683 G-protein beta/gamma-subunit complex binding 3/1236 22/18639 0.136363636363636 2.05637687555163 0.176012808375771 0.632197903501584 GO:0034062 5'-3' RNA polymerase activity 3/1236 22/18639 0.136363636363636 2.05637687555163 0.176012808375771 0.632197903501584 GO:0070034 telomerase RNA binding 3/1236 22/18639 0.136363636363636 2.05637687555163 0.176012808375771 0.632197903501584 GO:0097747 RNA polymerase activity 3/1236 22/18639 0.136363636363636 2.05637687555163 0.176012808375771 0.632197903501584 GO:0051087 protein-folding chaperone binding 12/1236 134/18639 0.0895522388059701 1.35045645558615 0.17834527348254 0.634669004310402 GO:0003823 antigen binding 15/1236 174/18639 0.0862068965517241 1.30000836960161 0.179812293571624 0.634669004310402 GO:0005539 glycosaminoglycan binding 20/1236 242/18639 0.0826446280991736 1.24628901548584 0.182453159133168 0.634669004310402 GO:0015297 antiporter activity 12/1236 135/18639 0.0888888888888889 1.34045307443366 0.184774359161888 0.634669004310402 GO:0008408 3'-5' exonuclease activity 6/1236 58/18639 0.103448275862069 1.56001004352193 0.184934150421762 0.634669004310402 GO:0019825 oxygen binding 4/1236 34/18639 0.117647058823529 1.77412906910337 0.186036827753988 0.634669004310402 GO:0051427 hormone receptor binding 4/1236 34/18639 0.117647058823529 1.77412906910337 0.186036827753988 0.634669004310402 GO:0035091 phosphatidylinositol binding 23/1236 284/18639 0.0809859154929577 1.22127546834404 0.186801780692645 0.634669004310402 GO:0000995 RNA polymerase III general transcription initiation factor activity 2/1236 12/18639 0.166666666666667 2.51334951456311 0.186909665663007 0.634669004310402 GO:0003995 acyl-CoA dehydrogenase activity 2/1236 12/18639 0.166666666666667 2.51334951456311 0.186909665663007 0.634669004310402 GO:0004300 enoyl-CoA hydratase activity 2/1236 12/18639 0.166666666666667 2.51334951456311 0.186909665663007 0.634669004310402 GO:0004859 phospholipase inhibitor activity 2/1236 12/18639 0.166666666666667 2.51334951456311 0.186909665663007 0.634669004310402 GO:0004875 complement receptor activity 2/1236 12/18639 0.166666666666667 2.51334951456311 0.186909665663007 0.634669004310402 GO:0008603 cAMP-dependent protein kinase regulator activity 2/1236 12/18639 0.166666666666667 2.51334951456311 0.186909665663007 0.634669004310402 GO:0034452 dynactin binding 2/1236 12/18639 0.166666666666667 2.51334951456311 0.186909665663007 0.634669004310402 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 2/1236 12/18639 0.166666666666667 2.51334951456311 0.186909665663007 0.634669004310402 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/1236 12/18639 0.166666666666667 2.51334951456311 0.186909665663007 0.634669004310402 GO:1990459 transferrin receptor binding 2/1236 12/18639 0.166666666666667 2.51334951456311 0.186909665663007 0.634669004310402 GO:0004180 carboxypeptidase activity 5/1236 46/18639 0.108695652173913 1.63914098775855 0.187325212725978 0.634669004310402 GO:0004860 protein kinase inhibitor activity 8/1236 84/18639 0.0952380952380952 1.43619972260749 0.192532479583082 0.647823368301313 GO:0008171 O-methyltransferase activity 3/1236 23/18639 0.130434782608696 1.96696918531026 0.193094429367425 0.647823368301313 GO:0140103 catalytic activity, acting on a glycoprotein 3/1236 23/18639 0.130434782608696 1.96696918531026 0.193094429367425 0.647823368301313 GO:0001786 phosphatidylserine binding 6/1236 59/18639 0.101694915254237 1.53356919532664 0.195203164721629 0.647823368301313 GO:0031593 polyubiquitin modification-dependent protein binding 6/1236 59/18639 0.101694915254237 1.53356919532664 0.195203164721629 0.647823368301313 GO:0045309 protein phosphorylated amino acid binding 6/1236 59/18639 0.101694915254237 1.53356919532664 0.195203164721629 0.647823368301313 GO:0070063 RNA polymerase binding 6/1236 59/18639 0.101694915254237 1.53356919532664 0.195203164721629 0.647823368301313 GO:0001784 phosphotyrosine residue binding 5/1236 47/18639 0.106382978723404 1.60426564759347 0.199055541586926 0.658682331490264 GO:0140713 histone chaperone activity 14/1236 164/18639 0.0853658536585366 1.28732536111769 0.199695660431375 0.658879577295381 GO:0008170 N-methyltransferase activity 9/1236 98/18639 0.0918367346938776 1.38490687537151 0.201514461521773 0.662953373412208 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 6/1236 60/18639 0.1 1.50800970873786 0.205680257262453 0.673124577422467 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 8/1236 86/18639 0.0930232558139535 1.40279972905848 0.20988983487116 0.673124577422467 GO:0004622 lysophospholipase activity 3/1236 24/18639 0.125 1.88501213592233 0.210563748660231 0.673124577422467 GO:0005540 hyaluronic acid binding 3/1236 24/18639 0.125 1.88501213592233 0.210563748660231 0.673124577422467 GO:0070840 dynein complex binding 3/1236 24/18639 0.125 1.88501213592233 0.210563748660231 0.673124577422467 GO:0038187 pattern recognition receptor activity 5/1236 48/18639 0.104166666666667 1.57084344660194 0.211028134512216 0.673124577422467 GO:0004535 poly(A)-specific ribonuclease activity 2/1236 13/18639 0.153846153846154 2.32001493651979 0.211722884704688 0.673124577422467 GO:0005338 nucleotide-sugar transmembrane transporter activity 2/1236 13/18639 0.153846153846154 2.32001493651979 0.211722884704688 0.673124577422467 GO:0005542 folic acid binding 2/1236 13/18639 0.153846153846154 2.32001493651979 0.211722884704688 0.673124577422467 GO:0009982 pseudouridine synthase activity 2/1236 13/18639 0.153846153846154 2.32001493651979 0.211722884704688 0.673124577422467 GO:0046974 histone H3K9 methyltransferase activity 2/1236 13/18639 0.153846153846154 2.32001493651979 0.211722884704688 0.673124577422467 GO:0140666 annealing activity 2/1236 13/18639 0.153846153846154 2.32001493651979 0.211722884704688 0.673124577422467 GO:0004190 aspartic-type endopeptidase activity 4/1236 36/18639 0.111111111111111 1.67556634304207 0.213924221673281 0.678019505859225 GO:0004857 enzyme inhibitor activity 32/1236 416/18639 0.0769230769230769 1.1600074682599 0.214457271016266 0.678019505859225 GO:0003684 damaged DNA binding 7/1236 74/18639 0.0945945945945946 1.42649567042771 0.218508332407645 0.686999881669465 GO:0035064 methylated histone binding 7/1236 74/18639 0.0945945945945946 1.42649567042771 0.218508332407645 0.686999881669465 GO:0070001 aspartic-type peptidase activity 4/1236 37/18639 0.108108108108108 1.6302807662031 0.228277957564246 0.710102277163074 GO:0005537 D-mannose binding 3/1236 25/18639 0.12 1.80961165048544 0.228358882083279 0.710102277163074 GO:0019211 phosphatase activator activity 3/1236 25/18639 0.12 1.80961165048544 0.228358882083279 0.710102277163074 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 3/1236 25/18639 0.12 1.80961165048544 0.228358882083279 0.710102277163074 GO:0140097 catalytic activity, acting on DNA 26/1236 336/18639 0.0773809523809524 1.16691227461859 0.233431395102899 0.713759584673061 GO:0048020 CCR chemokine receptor binding 5/1236 50/18639 0.1 1.50800970873786 0.235625195806221 0.713759584673061 GO:0005347 ATP transmembrane transporter activity 2/1236 14/18639 0.142857142857143 2.15429958391123 0.236822966903621 0.713759584673061 GO:0016530 metallochaperone activity 2/1236 14/18639 0.142857142857143 2.15429958391123 0.236822966903621 0.713759584673061 GO:0019763 immunoglobulin receptor activity 2/1236 14/18639 0.142857142857143 2.15429958391123 0.236822966903621 0.713759584673061 GO:0030983 mismatched DNA binding 2/1236 14/18639 0.142857142857143 2.15429958391123 0.236822966903621 0.713759584673061 GO:0031404 chloride ion binding 2/1236 14/18639 0.142857142857143 2.15429958391123 0.236822966903621 0.713759584673061 GO:0032036 myosin heavy chain binding 2/1236 14/18639 0.142857142857143 2.15429958391123 0.236822966903621 0.713759584673061 GO:0034236 protein kinase A catalytic subunit binding 2/1236 14/18639 0.142857142857143 2.15429958391123 0.236822966903621 0.713759584673061 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/1236 14/18639 0.142857142857143 2.15429958391123 0.236822966903621 0.713759584673061 GO:1901612 cardiolipin binding 2/1236 14/18639 0.142857142857143 2.15429958391123 0.236822966903621 0.713759584673061 GO:0005507 copper ion binding 6/1236 63/18639 0.0952380952380952 1.43619972260749 0.238235772309026 0.713759584673061 GO:0017022 myosin binding 7/1236 76/18639 0.0921052631578947 1.38895631067961 0.238339103604485 0.713759584673061 GO:0140034 methylation-dependent protein binding 7/1236 76/18639 0.0921052631578947 1.38895631067961 0.238339103604485 0.713759584673061 GO:0008198 ferrous iron binding 3/1236 26/18639 0.115384615384615 1.74001120238984 0.246420159828058 0.730252954059649 GO:0019865 immunoglobulin binding 3/1236 26/18639 0.115384615384615 1.74001120238984 0.246420159828058 0.730252954059649 GO:0030247 polysaccharide binding 3/1236 26/18639 0.115384615384615 1.74001120238984 0.246420159828058 0.730252954059649 GO:0120014 phospholipid transfer activity 3/1236 26/18639 0.115384615384615 1.74001120238984 0.246420159828058 0.730252954059649 GO:0019208 phosphatase regulator activity 10/1236 117/18639 0.0854700854700855 1.28889718695544 0.248166907707378 0.733514167312172 GO:0001664 G protein-coupled receptor binding 23/1236 297/18639 0.0774410774410774 1.16781896636266 0.248844283594128 0.733605875011262 GO:0005543 phospholipid binding 37/1236 497/18639 0.0744466800804829 1.1226631634467 0.254027325047552 0.74694563194034 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/1236 39/18639 0.102564102564103 1.54667662434653 0.257650745710854 0.754927373084086 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 18/1236 229/18639 0.0786026200873362 1.18533514223937 0.260506572150607 0.754927373084086 GO:0004559 alpha-mannosidase activity 2/1236 15/18639 0.133333333333333 2.01067961165049 0.262062894268837 0.754927373084086 GO:0005523 tropomyosin binding 2/1236 15/18639 0.133333333333333 2.01067961165049 0.262062894268837 0.754927373084086 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/1236 15/18639 0.133333333333333 2.01067961165049 0.262062894268837 0.754927373084086 GO:0050700 CARD domain binding 2/1236 15/18639 0.133333333333333 2.01067961165049 0.262062894268837 0.754927373084086 GO:0050780 dopamine receptor binding 2/1236 15/18639 0.133333333333333 2.01067961165049 0.262062894268837 0.754927373084086 GO:0120283 protein serine/threonine kinase binding 2/1236 15/18639 0.133333333333333 2.01067961165049 0.262062894268837 0.754927373084086 GO:0005044 scavenger receptor activity 3/1236 27/18639 0.111111111111111 1.67556634304207 0.264690388045143 0.758645430381913 GO:0008320 protein transmembrane transporter activity 3/1236 27/18639 0.111111111111111 1.67556634304207 0.264690388045143 0.758645430381913 GO:0005085 guanyl-nucleotide exchange factor activity 18/1236 230/18639 0.0782608695652174 1.18018151118615 0.266462398994111 0.759301676442634 GO:0019001 guanyl nucleotide binding 30/1236 400/18639 0.075 1.1310072815534 0.266926316211992 0.759301676442634 GO:0032561 guanyl ribonucleotide binding 30/1236 400/18639 0.075 1.1310072815534 0.266926316211992 0.759301676442634 GO:0016791 phosphatase activity 21/1236 273/18639 0.0769230769230769 1.1600074682599 0.271009753482303 0.763729947140469 GO:0004721 phosphoprotein phosphatase activity 14/1236 175/18639 0.08 1.20640776699029 0.271818832590144 0.763729947140469 GO:0008235 metalloexopeptidase activity 6/1236 66/18639 0.0909090909090909 1.37091791703442 0.27220815924398 0.763729947140469 GO:0050997 quaternary ammonium group binding 4/1236 40/18639 0.1 1.50800970873786 0.272609002466714 0.763729947140469 GO:0061791 GTPase motor activity 4/1236 40/18639 0.1 1.50800970873786 0.272609002466714 0.763729947140469 GO:1990606 membrane scission GTPase motor activity 4/1236 40/18639 0.1 1.50800970873786 0.272609002466714 0.763729947140469 GO:0016860 intramolecular oxidoreductase activity 5/1236 53/18639 0.0943396226415094 1.42265066862063 0.273866157256538 0.763729947140469 GO:0051018 protein kinase A binding 5/1236 53/18639 0.0943396226415094 1.42265066862063 0.273866157256538 0.763729947140469 GO:0004540 RNA nuclease activity 10/1236 121/18639 0.0826446280991736 1.24628901548584 0.28161242994405 0.770164197336038 GO:0003925 G protein activity 5/1236 54/18639 0.0925925925925926 1.39630528586839 0.286896135712309 0.770164197336038 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 5/1236 54/18639 0.0925925925925926 1.39630528586839 0.286896135712309 0.770164197336038 GO:0004707 MAP kinase activity 2/1236 16/18639 0.125 1.88501213592233 0.287313857132487 0.770164197336038 GO:0015385 sodium:proton antiporter activity 2/1236 16/18639 0.125 1.88501213592233 0.287313857132487 0.770164197336038 GO:0015923 mannosidase activity 2/1236 16/18639 0.125 1.88501213592233 0.287313857132487 0.770164197336038 GO:0016722 oxidoreductase activity, acting on metal ions 2/1236 16/18639 0.125 1.88501213592233 0.287313857132487 0.770164197336038 GO:0017070 U6 snRNA binding 2/1236 16/18639 0.125 1.88501213592233 0.287313857132487 0.770164197336038 GO:0030275 LRR domain binding 2/1236 16/18639 0.125 1.88501213592233 0.287313857132487 0.770164197336038 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1236 16/18639 0.125 1.88501213592233 0.287313857132487 0.770164197336038 GO:0055102 lipase inhibitor activity 2/1236 16/18639 0.125 1.88501213592233 0.287313857132487 0.770164197336038 GO:0070411 I-SMAD binding 2/1236 16/18639 0.125 1.88501213592233 0.287313857132487 0.770164197336038 GO:0001727 lipid kinase activity 4/1236 41/18639 0.0975609756097561 1.4712289841345 0.287708916009234 0.770164197336038 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/1236 41/18639 0.0975609756097561 1.4712289841345 0.287708916009234 0.770164197336038 GO:0016877 ligase activity, forming carbon-sulfur bonds 4/1236 41/18639 0.0975609756097561 1.4712289841345 0.287708916009234 0.770164197336038 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/1236 41/18639 0.0975609756097561 1.4712289841345 0.287708916009234 0.770164197336038 GO:0140828 metal cation:monoatomic cation antiporter activity 4/1236 41/18639 0.0975609756097561 1.4712289841345 0.287708916009234 0.770164197336038 GO:1990841 promoter-specific chromatin binding 6/1236 68/18639 0.0882352941176471 1.33059680182753 0.295469295184405 0.783180210976714 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 26/1236 349/18639 0.0744985673352436 1.12344562828609 0.296661176073632 0.783180210976714 GO:0005525 GTP binding 28/1236 378/18639 0.0740740740740741 1.11704422869471 0.298180557619393 0.783180210976714 GO:0008374 O-acyltransferase activity 5/1236 55/18639 0.0909090909090909 1.37091791703442 0.300036411515978 0.783180210976714 GO:0140313 molecular sequestering activity 5/1236 55/18639 0.0909090909090909 1.37091791703442 0.300036411515978 0.783180210976714 GO:0000510 H3-H4 histone complex chaperone activity 12/1236 151/18639 0.0794701986754967 1.19841831157976 0.300256067664248 0.783180210976714 GO:0140584 chromatin extrusion motor activity 12/1236 151/18639 0.0794701986754967 1.19841831157976 0.300256067664248 0.783180210976714 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 12/1236 151/18639 0.0794701986754967 1.19841831157976 0.300256067664248 0.783180210976714 GO:0140849 ATP-dependent H2AZ histone chaperone activity 12/1236 151/18639 0.0794701986754967 1.19841831157976 0.300256067664248 0.783180210976714 GO:0004402 histone acetyltransferase activity 4/1236 42/18639 0.0952380952380952 1.43619972260749 0.302921685126676 0.783180210976714 GO:0008307 structural constituent of muscle 4/1236 42/18639 0.0952380952380952 1.43619972260749 0.302921685126676 0.783180210976714 GO:0016859 cis-trans isomerase activity 4/1236 42/18639 0.0952380952380952 1.43619972260749 0.302921685126676 0.783180210976714 GO:0042056 chemoattractant activity 4/1236 42/18639 0.0952380952380952 1.43619972260749 0.302921685126676 0.783180210976714 GO:0048487 beta-tubulin binding 4/1236 42/18639 0.0952380952380952 1.43619972260749 0.302921685126676 0.783180210976714 GO:0051879 Hsp90 protein binding 4/1236 42/18639 0.0952380952380952 1.43619972260749 0.302921685126676 0.783180210976714 GO:0016407 acetyltransferase activity 8/1236 96/18639 0.0833333333333333 1.25667475728155 0.304230126559041 0.784615176824291 GO:0008236 serine-type peptidase activity 15/1236 194/18639 0.077319587628866 1.16598688819938 0.306431703309563 0.784615176824291 GO:0015616 DNA translocase activity 12/1236 152/18639 0.0789473684210526 1.19053398058252 0.308096873444557 0.784615176824291 GO:0140674 ATP-dependent histone chaperone activity 12/1236 152/18639 0.0789473684210526 1.19053398058252 0.308096873444557 0.784615176824291 GO:0004550 nucleoside diphosphate kinase activity 2/1236 17/18639 0.117647058823529 1.77412906910337 0.312463488920335 0.784615176824291 GO:0005092 GDP-dissociation inhibitor activity 2/1236 17/18639 0.117647058823529 1.77412906910337 0.312463488920335 0.784615176824291 GO:0016805 dipeptidase activity 2/1236 17/18639 0.117647058823529 1.77412906910337 0.312463488920335 0.784615176824291 GO:0017110 nucleoside diphosphate phosphatase activity 2/1236 17/18639 0.117647058823529 1.77412906910337 0.312463488920335 0.784615176824291 GO:0030169 low-density lipoprotein particle binding 2/1236 17/18639 0.117647058823529 1.77412906910337 0.312463488920335 0.784615176824291 GO:0045125 bioactive lipid receptor activity 2/1236 17/18639 0.117647058823529 1.77412906910337 0.312463488920335 0.784615176824291 GO:0070402 NADPH binding 2/1236 17/18639 0.117647058823529 1.77412906910337 0.312463488920335 0.784615176824291 GO:0070403 NAD+ binding 2/1236 17/18639 0.117647058823529 1.77412906910337 0.312463488920335 0.784615176824291 GO:1990226 histone methyltransferase binding 2/1236 17/18639 0.117647058823529 1.77412906910337 0.312463488920335 0.784615176824291 GO:1902936 phosphatidylinositol bisphosphate binding 9/1236 111/18639 0.0810810810810811 1.22271057465232 0.315615861290284 0.789974360936104 GO:0061775 cohesin loader activity 12/1236 153/18639 0.0784313725490196 1.18275271273558 0.315989744374442 0.789974360936104 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/1236 30/18639 0.1 1.50800970873786 0.320223771264658 0.79879995689096 GO:0004725 protein tyrosine phosphatase activity 8/1236 98/18639 0.0816326530612245 1.23102833366356 0.324196108970664 0.806935490530052 GO:0001046 core promoter sequence-specific DNA binding 4/1236 44/18639 0.0909090909090909 1.37091791703442 0.333574825536934 0.827111563997269 GO:0004519 endonuclease activity 10/1236 127/18639 0.078740157480315 1.18740921947863 0.333925635720024 0.827111563997269 GO:0017171 serine hydrolase activity 15/1236 198/18639 0.0757575757575758 1.14243159752868 0.334488288876429 0.827111563997269 GO:0015172 acidic amino acid transmembrane transporter activity 2/1236 18/18639 0.111111111111111 1.67556634304207 0.337414254674417 0.827138615670548 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/1236 18/18639 0.111111111111111 1.67556634304207 0.337414254674417 0.827138615670548 GO:0050811 GABA receptor binding 2/1236 18/18639 0.111111111111111 1.67556634304207 0.337414254674417 0.827138615670548 GO:0070628 proteasome binding 2/1236 18/18639 0.111111111111111 1.67556634304207 0.337414254674417 0.827138615670548 GO:0017116 single-stranded DNA helicase activity 5/1236 58/18639 0.0862068965517241 1.30000836960161 0.339937038078816 0.831527022024691 GO:0031490 chromatin DNA binding 10/1236 128/18639 0.078125 1.17813258495146 0.342829323795024 0.833612708991332 GO:0005518 collagen binding 6/1236 72/18639 0.0833333333333333 1.25667475728155 0.342993070571764 0.833612708991332 GO:0042379 chemokine receptor binding 6/1236 72/18639 0.0833333333333333 1.25667475728155 0.342993070571764 0.833612708991332 GO:0050660 flavin adenine dinucleotide binding 7/1236 86/18639 0.0813953488372093 1.22744976292617 0.344235067286474 0.834843592671257 GO:0008009 chemokine activity 4/1236 45/18639 0.0888888888888889 1.34045307443366 0.34896207377707 0.842706284546755 GO:0046915 transition metal ion transmembrane transporter activity 4/1236 45/18639 0.0888888888888889 1.34045307443366 0.34896207377707 0.842706284546755 GO:0140658 ATP-dependent chromatin remodeler activity 12/1236 158/18639 0.0759493670886076 1.14532382942116 0.356103881242463 0.85572298169567 GO:0071813 lipoprotein particle binding 3/1236 32/18639 0.09375 1.41375910194175 0.357368011738985 0.85572298169567 GO:0071814 protein-lipid complex binding 3/1236 32/18639 0.09375 1.41375910194175 0.357368011738985 0.85572298169567 GO:0140142 nucleocytoplasmic carrier activity 3/1236 32/18639 0.09375 1.41375910194175 0.357368011738985 0.85572298169567 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/1236 19/18639 0.105263157894737 1.5873786407767 0.36208198072373 0.861557752875123 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/1236 19/18639 0.105263157894737 1.5873786407767 0.36208198072373 0.861557752875123 GO:0043395 heparan sulfate proteoglycan binding 2/1236 19/18639 0.105263157894737 1.5873786407767 0.36208198072373 0.861557752875123 GO:0035402 histone H3T11 kinase activity 18/1236 247/18639 0.0728744939271255 1.09895444361464 0.373879631964736 0.863616926663242 GO:0030296 protein tyrosine kinase activator activity 3/1236 33/18639 0.0909090909090909 1.37091791703442 0.375848263622929 0.863616926663242 GO:0140311 protein sequestering activity 3/1236 33/18639 0.0909090909090909 1.37091791703442 0.375848263622929 0.863616926663242 GO:0003714 transcription corepressor activity 15/1236 204/18639 0.0735294117647059 1.10883066818961 0.377547293128634 0.863616926663242 GO:0019003 GDP binding 6/1236 75/18639 0.08 1.20640776699029 0.37911344057525 0.863616926663242 GO:0043495 protein-membrane adaptor activity 4/1236 47/18639 0.0851063829787234 1.28341251807478 0.379732853004949 0.863616926663242 GO:0061733 protein-lysine-acetyltransferase activity 4/1236 47/18639 0.0851063829787234 1.28341251807478 0.379732853004949 0.863616926663242 GO:0004252 serine-type endopeptidase activity 13/1236 176/18639 0.0738636363636364 1.11387080759047 0.384891304588325 0.863616926663242 GO:0043024 ribosomal small subunit binding 2/1236 20/18639 0.1 1.50800970873786 0.386394513892288 0.863616926663242 GO:0061608 nuclear import signal receptor activity 2/1236 20/18639 0.1 1.50800970873786 0.386394513892288 0.863616926663242 GO:0098631 cell adhesion mediator activity 6/1236 76/18639 0.0789473684210526 1.19053398058252 0.391179812315601 0.863616926663242 GO:0019209 kinase activator activity 11/1236 148/18639 0.0743243243243243 1.12081802676463 0.392745603419043 0.863616926663242 GO:0015035 protein-disulfide reductase activity 3/1236 34/18639 0.0882352941176471 1.33059680182753 0.394217112255408 0.863616926663242 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 3/1236 34/18639 0.0882352941176471 1.33059680182753 0.394217112255408 0.863616926663242 GO:0030332 cyclin binding 3/1236 34/18639 0.0882352941176471 1.33059680182753 0.394217112255408 0.863616926663242 GO:0052866 phosphatidylinositol phosphate phosphatase activity 3/1236 34/18639 0.0882352941176471 1.33059680182753 0.394217112255408 0.863616926663242 GO:0090482 vitamin transmembrane transporter activity 3/1236 34/18639 0.0882352941176471 1.33059680182753 0.394217112255408 0.863616926663242 GO:0030246 carbohydrate binding 20/1236 280/18639 0.0714285714285714 1.07714979195562 0.398287293611885 0.863616926663242 GO:0005319 lipid transporter activity 13/1236 178/18639 0.0730337078651685 1.10135540525799 0.400611195028783 0.863616926663242 GO:0051540 metal cluster binding 6/1236 77/18639 0.0779220779220779 1.17507250031522 0.403240095814989 0.863616926663242 GO:0015125 bile acid transmembrane transporter activity 2/1236 21/18639 0.0952380952380952 1.43619972260749 0.41029049955127 0.863616926663242 GO:0070182 DNA polymerase binding 2/1236 21/18639 0.0952380952380952 1.43619972260749 0.41029049955127 0.863616926663242 GO:1904047 S-adenosyl-L-methionine binding 2/1236 21/18639 0.0952380952380952 1.43619972260749 0.41029049955127 0.863616926663242 GO:0001222 transcription corepressor binding 4/1236 49/18639 0.0816326530612245 1.23102833366356 0.410344786330629 0.863616926663242 GO:0052689 carboxylic ester hydrolase activity 7/1236 92/18639 0.0760869565217391 1.14739869143098 0.410392817604753 0.863616926663242 GO:0030695 GTPase regulator activity 34/1236 489/18639 0.0695296523517382 1.0485139079159 0.412224214005185 0.863616926663242 GO:0010485 histone H4 acetyltransferase activity 3/1236 35/18639 0.0857142857142857 1.29257975034674 0.412440579917118 0.863616926663242 GO:0140789 histone phosphatase activity 10/1236 136/18639 0.0735294117647059 1.10883066818961 0.415039573336193 0.863616926663242 GO:0060589 nucleoside-triphosphatase regulator activity 34/1236 490/18639 0.0693877551020408 1.04637408361403 0.417016840297813 0.863616926663242 GO:0004536 DNA nuclease activity 5/1236 64/18639 0.078125 1.17813258495146 0.420359646377689 0.863616926663242 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 9/1236 122/18639 0.0737704918032787 1.11246617857711 0.420427598965651 0.863616926663242 GO:0015605 organophosphate ester transmembrane transporter activity 4/1236 50/18639 0.08 1.20640776699029 0.425537794202316 0.863616926663242 GO:0046332 SMAD binding 6/1236 79/18639 0.0759493670886076 1.14532382942116 0.427298506911555 0.863616926663242 GO:0004033 aldo-keto reductase (NADPH) activity 3/1236 36/18639 0.0833333333333333 1.25667475728155 0.430487521575649 0.863616926663242 GO:0005484 SNAP receptor activity 3/1236 36/18639 0.0833333333333333 1.25667475728155 0.430487521575649 0.863616926663242 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/1236 36/18639 0.0833333333333333 1.25667475728155 0.430487521575649 0.863616926663242 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/1236 36/18639 0.0833333333333333 1.25667475728155 0.430487521575649 0.863616926663242 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/1236 36/18639 0.0833333333333333 1.25667475728155 0.430487521575649 0.863616926663242 GO:0008093 cytoskeletal anchor activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0015377 chloride:monoatomic cation symporter activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0032931 histone H3K56 acetyltransferase activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0043992 histone H3K9 acetyltransferase activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0043993 histone H3K18 acetyltransferase activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0043994 histone H3K23 acetyltransferase activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0043999 histone H2AK5 acetyltransferase activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0044012 histone H2AK9 acetyltransferase activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0044014 histone H2BK5 acetyltransferase activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0044015 histone H2BK12 acetyltransferase activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0044016 histone H3K4 acetyltransferase activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0044017 histone H3K27 acetyltransferase activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0044018 histone H3K36 acetyltransferase activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0046972 histone H4K16 acetyltransferase activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0140517 protein-RNA adaptor activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0140908 histone H3K122 acetyltransferase activity 2/1236 22/18639 0.0909090909090909 1.37091791703442 0.43371826866882 0.863616926663242 GO:0003774 cytoskeletal motor activity 11/1236 153/18639 0.0718954248366013 1.08418998667428 0.435827346632141 0.863616926663242 GO:0030295 protein kinase activator activity 10/1236 139/18639 0.0719424460431655 1.08489907103443 0.442240306912129 0.863616926663242 GO:0140101 catalytic activity, acting on a tRNA 10/1236 139/18639 0.0719424460431655 1.08489907103443 0.442240306912129 0.863616926663242 GO:0015291 secondary active transmembrane transporter activity 20/1236 287/18639 0.0696864111498258 1.05087784581036 0.442319983172422 0.863616926663242 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 17/1236 243/18639 0.0699588477366255 1.05498621598945 0.445729079836987 0.863616926663242 GO:0008237 metallopeptidase activity 13/1236 184/18639 0.0706521739130435 1.06544164204306 0.447906006442032 0.863616926663242 GO:0001618 virus receptor activity 6/1236 81/18639 0.0740740740740741 1.11704422869471 0.451204364077991 0.863616926663242 GO:0042578 phosphoric ester hydrolase activity 25/1236 363/18639 0.068870523415978 1.03857417957153 0.451970483691214 0.863616926663242 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 4/1236 52/18639 0.0769230769230769 1.1600074682599 0.455601390645559 0.863616926663242 GO:0000295 adenine nucleotide transmembrane transporter activity 2/1236 23/18639 0.0869565217391304 1.31131279020684 0.456634824792762 0.863616926663242 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/1236 23/18639 0.0869565217391304 1.31131279020684 0.456634824792762 0.863616926663242 GO:0044013 histone H2B acetyltransferase activity 2/1236 23/18639 0.0869565217391304 1.31131279020684 0.456634824792762 0.863616926663242 GO:0140102 catalytic activity, acting on a rRNA 2/1236 23/18639 0.0869565217391304 1.31131279020684 0.456634824792762 0.863616926663242 GO:0000287 magnesium ion binding 16/1236 230/18639 0.0695652173913043 1.04905023216547 0.458675349553764 0.863616926663242 GO:0004676 3-phosphoinositide-dependent protein kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0004711 ribosomal protein S6 kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0035175 histone H3S10 kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0035979 histone H2AXS139 kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0044022 histone H3S28 kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0044023 histone H4S1 kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0044024 histone H2AS1 kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0044025 histone H2BS14 kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0072354 histone H3T3 kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0072371 histone H2AS121 kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0072518 Rho-dependent protein serine/threonine kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0140823 histone H2BS36 kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0140855 histone H3S57 kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0140995 histone H2A kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0140997 histone H4 kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0140998 histone H2B kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:1990244 histone H2AT120 kinase activity 17/1236 245/18639 0.0693877551020408 1.04637408361403 0.459422541856374 0.863616926663242 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5/1236 67/18639 0.0746268656716418 1.12538037965512 0.460048283403084 0.863616926663242 GO:0140272 exogenous protein binding 6/1236 82/18639 0.0731707317073171 1.10342173810088 0.463075327399535 0.863616926663242 GO:0004677 DNA-dependent protein kinase activity 17/1236 246/18639 0.0691056910569106 1.04212053042861 0.466259658840638 0.863616926663242 GO:0140857 histone H3T45 kinase activity 17/1236 246/18639 0.0691056910569106 1.04212053042861 0.466259658840638 0.863616926663242 GO:0005200 structural constituent of cytoskeleton 8/1236 112/18639 0.0714285714285714 1.07714979195562 0.466947084030241 0.863616926663242 GO:0008017 microtubule binding 19/1236 276/18639 0.0688405797101449 1.03812262558041 0.467140902870341 0.863616926663242 GO:0019783 ubiquitin-like protein peptidase activity 9/1236 127/18639 0.0708661417322835 1.06866829753077 0.468257399081392 0.863616926663242 GO:0005544 calcium-dependent phospholipid binding 4/1236 53/18639 0.0754716981132075 1.1381205348965 0.470436919901806 0.863616926663242 GO:0034212 protein N-acetyltransferase activity 4/1236 53/18639 0.0754716981132075 1.1381205348965 0.470436919901806 0.863616926663242 GO:0035403 histone H3T6 kinase activity 17/1236 247/18639 0.0688259109311741 1.03790141896938 0.473087747783639 0.863616926663242 GO:0042626 ATPase-coupled transmembrane transporter activity 7/1236 98/18639 0.0714285714285714 1.07714979195562 0.476127893931736 0.863616926663242 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/1236 24/18639 0.0833333333333333 1.25667475728155 0.479004922622992 0.863616926663242 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/1236 24/18639 0.0833333333333333 1.25667475728155 0.479004922622992 0.863616926663242 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/1236 24/18639 0.0833333333333333 1.25667475728155 0.479004922622992 0.863616926663242 GO:0015149 hexose transmembrane transporter activity 2/1236 24/18639 0.0833333333333333 1.25667475728155 0.479004922622992 0.863616926663242 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/1236 24/18639 0.0833333333333333 1.25667475728155 0.479004922622992 0.863616926663242 GO:0030552 cAMP binding 2/1236 24/18639 0.0833333333333333 1.25667475728155 0.479004922622992 0.863616926663242 GO:0043998 histone H2A acetyltransferase activity 2/1236 24/18639 0.0833333333333333 1.25667475728155 0.479004922622992 0.863616926663242 GO:0055056 D-glucose transmembrane transporter activity 2/1236 24/18639 0.0833333333333333 1.25667475728155 0.479004922622992 0.863616926663242 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/1236 24/18639 0.0833333333333333 1.25667475728155 0.479004922622992 0.863616926663242 GO:0004679 AMP-activated protein kinase activity 17/1236 248/18639 0.0685483870967742 1.03371633260257 0.479904874310579 0.863616926663242 GO:0050661 NADP binding 4/1236 54/18639 0.0740740740740741 1.11704422869471 0.485120182636966 0.863616926663242 GO:0015631 tubulin binding 26/1236 385/18639 0.0675324675324675 1.01839616693986 0.491003610468181 0.863616926663242 GO:0000182 rDNA binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0003796 lysozyme activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0004955 prostaglandin receptor activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0005031 tumor necrosis factor receptor activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0005345 purine nucleobase transmembrane transporter activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0005528 FK506 binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0008190 eukaryotic initiation factor 4E binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0015643 toxic substance binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0016783 sulfurtransferase activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0019911 structural constituent of myelin sheath 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0032356 oxidized DNA binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0033204 ribonuclease P RNA binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0042975 peroxisome proliferator activated receptor binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0043208 glycosphingolipid binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0043295 glutathione binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0043422 protein kinase B binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0050815 phosphoserine residue binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0051864 histone H3K36 demethylase activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0098505 G-rich strand telomeric DNA binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0099122 RNA polymerase II C-terminal domain binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0140999 histone H3K4 trimethyltransferase activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:1905394 retromer complex binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:1990757 ubiquitin ligase activator activity 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:1990763 arrestin family protein binding 1/1236 10/18639 0.1 1.50800970873786 0.496568223641457 0.863616926663242 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 9/1236 130/18639 0.0692307692307692 1.04400672143391 0.496596234450179 0.863616926663242 GO:0101005 deubiquitinase activity 8/1236 115/18639 0.0695652173913043 1.04905023216547 0.4971014900355 0.863616926663242 GO:0098632 cell-cell adhesion mediator activity 4/1236 55/18639 0.0727272727272727 1.09673433362754 0.499636556842533 0.863616926663242 GO:0015144 carbohydrate transmembrane transporter activity 3/1236 40/18639 0.075 1.1310072815534 0.500381339836805 0.863616926663242 GO:0030331 nuclear estrogen receptor binding 3/1236 40/18639 0.075 1.1310072815534 0.500381339836805 0.863616926663242 GO:0071949 FAD binding 3/1236 40/18639 0.075 1.1310072815534 0.500381339836805 0.863616926663242 GO:0140662 ATP-dependent protein folding chaperone 3/1236 40/18639 0.075 1.1310072815534 0.500381339836805 0.863616926663242 GO:0000030 mannosyltransferase activity 2/1236 25/18639 0.08 1.20640776699029 0.500800230496011 0.863616926663242 GO:0003707 nuclear steroid receptor activity 2/1236 25/18639 0.08 1.20640776699029 0.500800230496011 0.863616926663242 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/1236 25/18639 0.08 1.20640776699029 0.500800230496011 0.863616926663242 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/1236 25/18639 0.08 1.20640776699029 0.500800230496011 0.863616926663242 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/1236 25/18639 0.08 1.20640776699029 0.500800230496011 0.863616926663242 GO:0016887 ATP hydrolysis activity 28/1236 417/18639 0.0671462829736211 1.01257246629881 0.501078705592745 0.863616926663242 GO:0004866 endopeptidase inhibitor activity 11/1236 161/18639 0.0683229813664596 1.03031719230537 0.504131784430073 0.863616926663242 GO:0005178 integrin binding 11/1236 161/18639 0.0683229813664596 1.03031719230537 0.504131784430073 0.863616926663242 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 9/1236 132/18639 0.0681818181818182 1.02818843777582 0.515258505547268 0.863616926663242 GO:0001530 lipopolysaccharide binding 3/1236 41/18639 0.0731707317073171 1.10342173810088 0.517171268033719 0.863616926663242 GO:0004812 aminoacyl-tRNA ligase activity 3/1236 41/18639 0.0731707317073171 1.10342173810088 0.517171268033719 0.863616926663242 GO:0016875 ligase activity, forming carbon-oxygen bonds 3/1236 41/18639 0.0731707317073171 1.10342173810088 0.517171268033719 0.863616926663242 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/1236 26/18639 0.0769230769230769 1.1600074682599 0.521998569718341 0.863616926663242 GO:0004529 DNA exonuclease activity 2/1236 26/18639 0.0769230769230769 1.1600074682599 0.521998569718341 0.863616926663242 GO:0005160 transforming growth factor beta receptor binding 2/1236 26/18639 0.0769230769230769 1.1600074682599 0.521998569718341 0.863616926663242 GO:0015145 monosaccharide transmembrane transporter activity 2/1236 26/18639 0.0769230769230769 1.1600074682599 0.521998569718341 0.863616926663242 GO:0015216 purine nucleotide transmembrane transporter activity 2/1236 26/18639 0.0769230769230769 1.1600074682599 0.521998569718341 0.863616926663242 GO:0034237 protein kinase A regulatory subunit binding 2/1236 26/18639 0.0769230769230769 1.1600074682599 0.521998569718341 0.863616926663242 GO:0043548 phosphatidylinositol 3-kinase binding 2/1236 26/18639 0.0769230769230769 1.1600074682599 0.521998569718341 0.863616926663242 GO:0050681 nuclear androgen receptor binding 2/1236 26/18639 0.0769230769230769 1.1600074682599 0.521998569718341 0.863616926663242 GO:0052742 phosphatidylinositol kinase activity 2/1236 26/18639 0.0769230769230769 1.1600074682599 0.521998569718341 0.863616926663242 GO:0097602 cullin family protein binding 2/1236 26/18639 0.0769230769230769 1.1600074682599 0.521998569718341 0.863616926663242 GO:0051020 GTPase binding 21/1236 315/18639 0.0666666666666667 1.00533980582524 0.522629006945665 0.863616926663242 GO:0003924 GTPase activity 22/1236 331/18639 0.0664652567975831 1.00230252544511 0.527546896452929 0.863616926663242 GO:0015932 nucleobase-containing compound transmembrane transporter activity 4/1236 57/18639 0.0701754385964912 1.05825242718447 0.528115784499682 0.863616926663242 GO:0004722 protein serine/threonine phosphatase activity 7/1236 103/18639 0.0679611650485437 1.0248609671034 0.529379899011913 0.863616926663242 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0002162 dystroglycan binding 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0004954 prostanoid receptor activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0005114 type II transforming growth factor beta receptor binding 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0008172 S-methyltransferase activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0008526 phosphatidylinositol transfer activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0010854 adenylate cyclase regulator activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0015205 nucleobase transmembrane transporter activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0019206 nucleoside kinase activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0032050 clathrin heavy chain binding 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0032794 GTPase activating protein binding 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0034511 U3 snoRNA binding 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0035252 UDP-xylosyltransferase activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0042285 xylosyltransferase activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0043522 leucine zipper domain binding 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0045294 alpha-catenin binding 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0047676 arachidonate-CoA ligase activity 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0070697 activin receptor binding 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0140031 phosphorylation-dependent protein binding 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:1900750 oligopeptide binding 1/1236 11/18639 0.0909090909090909 1.37091791703442 0.529969999130167 0.863616926663242 GO:0004520 DNA endonuclease activity 3/1236 42/18639 0.0714285714285714 1.07714979195562 0.533652005180414 0.863616926663242 GO:0043539 protein serine/threonine kinase activator activity 5/1236 73/18639 0.0684931506849315 1.03288336214922 0.536658087794539 0.863616926663242 GO:0008266 poly(U) RNA binding 2/1236 27/18639 0.0740740740740741 1.11704422869471 0.542583224252196 0.863616926663242 GO:0008395 steroid hydroxylase activity 2/1236 27/18639 0.0740740740740741 1.11704422869471 0.542583224252196 0.863616926663242 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/1236 27/18639 0.0740740740740741 1.11704422869471 0.542583224252196 0.863616926663242 GO:0035255 ionotropic glutamate receptor binding 2/1236 27/18639 0.0740740740740741 1.11704422869471 0.542583224252196 0.863616926663242 GO:0003727 single-stranded RNA binding 6/1236 89/18639 0.0674157303370786 1.01663575869968 0.543826705889898 0.863616926663242 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 6/1236 89/18639 0.0674157303370786 1.01663575869968 0.543826705889898 0.863616926663242 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 6/1236 89/18639 0.0674157303370786 1.01663575869968 0.543826705889898 0.863616926663242 GO:0003678 DNA helicase activity 5/1236 74/18639 0.0675675675675676 1.01892547887694 0.54894835797738 0.863616926663242 GO:0008200 ion channel inhibitor activity 3/1236 43/18639 0.0697674418604651 1.05209979679386 0.549809455081257 0.863616926663242 GO:0016779 nucleotidyltransferase activity 9/1236 136/18639 0.0661764705882353 0.997947601370645 0.551874201279551 0.863616926663242 GO:0044325 transmembrane transporter binding 9/1236 136/18639 0.0661764705882353 0.997947601370645 0.551874201279551 0.863616926663242 GO:0140793 histone H2AXY142 phosphatase activity 6/1236 90/18639 0.0666666666666667 1.00533980582524 0.554935992649288 0.863616926663242 GO:0016922 nuclear receptor binding 9/1236 137/18639 0.0656934306569343 0.990663312309546 0.560857370939177 0.863616926663242 GO:0000340 RNA 7-methylguanosine cap binding 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0003720 telomerase activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0004000 adenosine deaminase activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0004032 aldose reductase (NADPH) activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0004126 cytidine deaminase activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0004526 ribonuclease P activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0005049 nuclear export signal receptor activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0005078 MAP-kinase scaffold activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0005527 macrolide binding 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0008179 adenylate cyclase binding 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0010853 cyclase activator activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0015132 prostaglandin transmembrane transporter activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0015368 calcium:monoatomic cation antiporter activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0016208 AMP binding 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0016801 hydrolase activity, acting on ether bonds 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0016803 ether hydrolase activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0016840 carbon-nitrogen lyase activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0031543 peptidyl-proline dioxygenase activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0035251 UDP-glucosyltransferase activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0035497 cAMP response element binding 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0043047 single-stranded telomeric DNA binding 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0097677 STAT family protein binding 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0140900 chloride:bicarbonate antiporter activity 1/1236 12/18639 0.0833333333333333 1.25667475728155 0.561157302172636 0.863616926663242 GO:0019789 SUMO transferase activity 2/1236 28/18639 0.0714285714285714 1.07714979195562 0.562542314779426 0.863616926663242 GO:0036408 histone H3K14 acetyltransferase activity 2/1236 28/18639 0.0714285714285714 1.07714979195562 0.562542314779426 0.863616926663242 GO:0046875 ephrin receptor binding 2/1236 28/18639 0.0714285714285714 1.07714979195562 0.562542314779426 0.863616926663242 GO:0046966 nuclear thyroid hormone receptor binding 2/1236 28/18639 0.0714285714285714 1.07714979195562 0.562542314779426 0.863616926663242 GO:0051019 mitogen-activated protein kinase binding 2/1236 28/18639 0.0714285714285714 1.07714979195562 0.562542314779426 0.863616926663242 GO:0051119 sugar transmembrane transporter activity 2/1236 28/18639 0.0714285714285714 1.07714979195562 0.562542314779426 0.863616926663242 GO:0051537 2 iron, 2 sulfur cluster binding 2/1236 28/18639 0.0714285714285714 1.07714979195562 0.562542314779426 0.863616926663242 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/1236 28/18639 0.0714285714285714 1.07714979195562 0.562542314779426 0.863616926663242 GO:0016248 channel inhibitor activity 3/1236 44/18639 0.0681818181818182 1.02818843777582 0.565631501145476 0.863616926663242 GO:0019205 nucleobase-containing compound kinase activity 3/1236 44/18639 0.0681818181818182 1.02818843777582 0.565631501145476 0.863616926663242 GO:0030547 signaling receptor inhibitor activity 3/1236 44/18639 0.0681818181818182 1.02818843777582 0.565631501145476 0.863616926663242 GO:0030414 peptidase inhibitor activity 11/1236 169/18639 0.0650887573964497 0.981544780835296 0.570056376308293 0.863616926663242 GO:0051536 iron-sulfur cluster binding 5/1236 76/18639 0.0657894736842105 0.992111650485437 0.573044184857547 0.863616926663242 GO:1901981 phosphatidylinositol phosphate binding 12/1236 185/18639 0.0648648648648649 0.978168459721858 0.574240942570472 0.863616926663242 GO:0004843 cysteine-type deubiquitinase activity 7/1236 108/18639 0.0648148148148148 0.977413700107875 0.58040301286272 0.863616926663242 GO:0051539 4 iron, 4 sulfur cluster binding 3/1236 45/18639 0.0666666666666667 1.00533980582524 0.581107888814648 0.863616926663242 GO:0141110 transporter inhibitor activity 3/1236 45/18639 0.0666666666666667 1.00533980582524 0.581107888814648 0.863616926663242 GO:0004181 metallocarboxypeptidase activity 2/1236 29/18639 0.0689655172413793 1.04000669568129 0.581868231651698 0.863616926663242 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/1236 29/18639 0.0689655172413793 1.04000669568129 0.581868231651698 0.863616926663242 GO:0010484 histone H3 acetyltransferase activity 2/1236 29/18639 0.0689655172413793 1.04000669568129 0.581868231651698 0.863616926663242 GO:0051861 glycolipid binding 2/1236 29/18639 0.0689655172413793 1.04000669568129 0.581868231651698 0.863616926663242 GO:0097472 cyclin-dependent protein kinase activity 2/1236 29/18639 0.0689655172413793 1.04000669568129 0.581868231651698 0.863616926663242 GO:0004386 helicase activity 10/1236 155/18639 0.0645161290322581 0.972909489508299 0.582372369138227 0.863616926663242 GO:0016836 hydro-lyase activity 4/1236 61/18639 0.0655737704918033 0.988858825401878 0.582550553889794 0.863616926663242 GO:0003724 RNA helicase activity 5/1236 77/18639 0.0649350649350649 0.979227083596016 0.584836135485503 0.863616926663242 GO:0051213 dioxygenase activity 6/1236 93/18639 0.0645161290322581 0.972909489508299 0.587482713806093 0.863616926663242 GO:0002161 aminoacyl-tRNA editing activity 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0003964 RNA-directed DNA polymerase activity 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0005035 death receptor activity 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0008035 high-density lipoprotein particle binding 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0008253 5'-nucleotidase activity 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0019104 DNA N-glycosylase activity 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0030955 potassium ion binding 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0031432 titin binding 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0035673 oligopeptide transmembrane transporter activity 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0051011 microtubule minus-end binding 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0070700 BMP receptor binding 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0071714 icosanoid transmembrane transporter activity 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0089720 caspase binding 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:1901338 catecholamine binding 1/1236 13/18639 0.0769230769230769 1.1600074682599 0.590276836961631 0.863616926663242 GO:0016410 N-acyltransferase activity 6/1236 94/18639 0.0638297872340425 0.962559388556083 0.598053829328363 0.863616926663242 GO:0001968 fibronectin binding 2/1236 30/18639 0.0666666666666667 1.00533980582524 0.600557121679343 0.863616926663242 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/1236 30/18639 0.0666666666666667 1.00533980582524 0.600557121679343 0.863616926663242 GO:0008187 poly-pyrimidine tract binding 2/1236 30/18639 0.0666666666666667 1.00533980582524 0.600557121679343 0.863616926663242 GO:0015215 nucleotide transmembrane transporter activity 2/1236 30/18639 0.0666666666666667 1.00533980582524 0.600557121679343 0.863616926663242 GO:0032452 histone demethylase activity 2/1236 30/18639 0.0666666666666667 1.00533980582524 0.600557121679343 0.863616926663242 GO:0033612 receptor serine/threonine kinase binding 2/1236 30/18639 0.0666666666666667 1.00533980582524 0.600557121679343 0.863616926663242 GO:0043995 histone H4K5 acetyltransferase activity 2/1236 30/18639 0.0666666666666667 1.00533980582524 0.600557121679343 0.863616926663242 GO:0043996 histone H4K8 acetyltransferase activity 2/1236 30/18639 0.0666666666666667 1.00533980582524 0.600557121679343 0.863616926663242 GO:0043997 histone H4K12 acetyltransferase activity 2/1236 30/18639 0.0666666666666667 1.00533980582524 0.600557121679343 0.863616926663242 GO:0048019 receptor antagonist activity 2/1236 30/18639 0.0666666666666667 1.00533980582524 0.600557121679343 0.863616926663242 GO:0031267 small GTPase binding 18/1236 283/18639 0.0636042402826855 0.959158118631857 0.607822900806853 0.863616926663242 GO:0008186 ATP-dependent activity, acting on RNA 5/1236 79/18639 0.0632911392405063 0.954436524517636 0.607878458818946 0.863616926663242 GO:0016835 carbon-oxygen lyase activity 5/1236 79/18639 0.0632911392405063 0.954436524517636 0.607878458818946 0.863616926663242 GO:0061749 forked DNA-dependent helicase activity 3/1236 47/18639 0.0638297872340425 0.962559388556083 0.610991285963504 0.863616926663242 GO:0140359 ABC-type transporter activity 3/1236 47/18639 0.0638297872340425 0.962559388556083 0.610991285963504 0.863616926663242 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/1236 47/18639 0.0638297872340425 0.962559388556083 0.610991285963504 0.863616926663242 GO:0004065 arylsulfatase activity 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0004705 JUN kinase activity 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0005313 L-glutamate transmembrane transporter activity 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0008174 mRNA methyltransferase activity 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0008191 metalloendopeptidase inhibitor activity 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0015386 potassium:proton antiporter activity 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0019992 diacylglycerol binding 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0032454 histone H3K9 demethylase activity 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0046030 inositol trisphosphate phosphatase activity 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0061665 SUMO ligase activity 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0061783 peptidoglycan muralytic activity 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0070742 C2H2 zinc finger domain binding 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0071933 Arp2/3 complex binding 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0098847 sequence-specific single stranded DNA binding 1/1236 14/18639 0.0714285714285714 1.07714979195562 0.617465596196863 0.863616926663242 GO:0005164 tumor necrosis factor receptor binding 2/1236 31/18639 0.0645161290322581 0.972909489508299 0.618608424120895 0.863616926663242 GO:0016411 acylglycerol O-acyltransferase activity 2/1236 31/18639 0.0645161290322581 0.972909489508299 0.618608424120895 0.863616926663242 GO:0016878 acid-thiol ligase activity 2/1236 31/18639 0.0645161290322581 0.972909489508299 0.618608424120895 0.863616926663242 GO:0017147 Wnt-protein binding 2/1236 31/18639 0.0645161290322581 0.972909489508299 0.618608424120895 0.863616926663242 GO:0070273 phosphatidylinositol-4-phosphate binding 2/1236 31/18639 0.0645161290322581 0.972909489508299 0.618608424120895 0.863616926663242 GO:0072349 modified amino acid transmembrane transporter activity 2/1236 31/18639 0.0645161290322581 0.972909489508299 0.618608424120895 0.863616926663242 GO:0140457 protein demethylase activity 2/1236 31/18639 0.0645161290322581 0.972909489508299 0.618608424120895 0.863616926663242 GO:0019955 cytokine binding 9/1236 144/18639 0.0625 0.942506067961165 0.62144578914072 0.866512248986139 GO:0009378 four-way junction helicase activity 3/1236 48/18639 0.0625 0.942506067961165 0.625386061988057 0.86880438232123 GO:0036121 double-stranded DNA helicase activity 3/1236 48/18639 0.0625 0.942506067961165 0.625386061988057 0.86880438232123 GO:0043138 3'-5' DNA helicase activity 3/1236 48/18639 0.0625 0.942506067961165 0.625386061988057 0.86880438232123 GO:0035591 signaling adaptor activity 8/1236 129/18639 0.062015503875969 0.935199819372319 0.628952983555038 0.870687895521349 GO:0030971 receptor tyrosine kinase binding 5/1236 81/18639 0.0617283950617284 0.930870190578928 0.630165645411233 0.870687895521349 GO:0015106 bicarbonate transmembrane transporter activity 2/1236 32/18639 0.0625 0.942506067961165 0.636024451613022 0.870687895521349 GO:0042910 xenobiotic transmembrane transporter activity 2/1236 32/18639 0.0625 0.942506067961165 0.636024451613022 0.870687895521349 GO:0070717 poly-purine tract binding 2/1236 32/18639 0.0625 0.942506067961165 0.636024451613022 0.870687895521349 GO:0016763 pentosyltransferase activity 3/1236 49/18639 0.0612244897959184 0.923271250247672 0.639410493009194 0.870687895521349 GO:0004467 long-chain fatty acid-CoA ligase activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0004953 icosanoid receptor activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0008242 omega peptidase activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0008252 nucleotidase activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0015116 sulfate transmembrane transporter activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0015929 hexosaminidase activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0016846 carbon-sulfur lyase activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0017081 chloride channel regulator activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0034483 heparan sulfate sulfotransferase activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0042809 nuclear vitamin D receptor binding 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0048531 beta-1,3-galactosyltransferase activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0061578 K63-linked deubiquitinase activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0140161 monocarboxylate:sodium symporter activity 1/1236 15/18639 0.0666666666666667 1.00533980582524 0.642851503477436 0.870687895521349 GO:0001221 transcription coregulator binding 7/1236 115/18639 0.0608695652173913 0.917918953144787 0.646970526753856 0.875222345489423 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/1236 33/18639 0.0606060606060606 0.913945278022948 0.652810012128513 0.879975491408387 GO:0019239 deaminase activity 2/1236 33/18639 0.0606060606060606 0.913945278022948 0.652810012128513 0.879975491408387 GO:0019956 chemokine binding 2/1236 33/18639 0.0606060606060606 0.913945278022948 0.652810012128513 0.879975491408387 GO:0015294 solute:monoatomic cation symporter activity 7/1236 116/18639 0.0603448275862069 0.910005858721125 0.655956585469803 0.882775735146236 GO:0051117 ATPase binding 5/1236 84/18639 0.0595238095238095 0.897624826629681 0.662112166004897 0.882775735146236 GO:0005048 signal sequence binding 3/1236 51/18639 0.0588235294117647 0.887064534551685 0.666338977706621 0.882775735146236 GO:0030544 Hsp70 protein binding 3/1236 51/18639 0.0588235294117647 0.887064534551685 0.666338977706621 0.882775735146236 GO:0000062 fatty-acyl-CoA binding 1/1236 16/18639 0.0625 0.942506067961165 0.666554013233766 0.882775735146236 GO:0005149 interleukin-1 receptor binding 1/1236 16/18639 0.0625 0.942506067961165 0.666554013233766 0.882775735146236 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/1236 16/18639 0.0625 0.942506067961165 0.666554013233766 0.882775735146236 GO:0005521 lamin binding 1/1236 16/18639 0.0625 0.942506067961165 0.666554013233766 0.882775735146236 GO:0008142 oxysterol binding 1/1236 16/18639 0.0625 0.942506067961165 0.666554013233766 0.882775735146236 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1236 16/18639 0.0625 0.942506067961165 0.666554013233766 0.882775735146236 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1236 16/18639 0.0625 0.942506067961165 0.666554013233766 0.882775735146236 GO:0043023 ribosomal large subunit binding 1/1236 16/18639 0.0625 0.942506067961165 0.666554013233766 0.882775735146236 GO:0097027 ubiquitin-protein transferase activator activity 1/1236 16/18639 0.0625 0.942506067961165 0.666554013233766 0.882775735146236 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/1236 16/18639 0.0625 0.942506067961165 0.666554013233766 0.882775735146236 GO:0140328 floppase activity 1/1236 16/18639 0.0625 0.942506067961165 0.666554013233766 0.882775735146236 GO:0005548 phospholipid transporter activity 4/1236 68/18639 0.0588235294117647 0.887064534551685 0.668441104965604 0.882887555349547 GO:0140223 general transcription initiation factor activity 4/1236 68/18639 0.0588235294117647 0.887064534551685 0.668441104965604 0.882887555349547 GO:0015020 glucuronosyltransferase activity 2/1236 34/18639 0.0588235294117647 0.887064534551685 0.668972068370582 0.882887555349547 GO:0008080 N-acetyltransferase activity 4/1236 69/18639 0.0579710144927536 0.874208526804559 0.67966404282564 0.889257225925835 GO:0016247 channel regulator activity 10/1236 168/18639 0.0595238095238095 0.897624826629681 0.683360495592418 0.889257225925835 GO:0034061 DNA polymerase activity 2/1236 35/18639 0.0571428571428571 0.861719833564494 0.684519431307155 0.889257225925835 GO:0043015 gamma-tubulin binding 2/1236 35/18639 0.0571428571428571 0.861719833564494 0.684519431307155 0.889257225925835 GO:0061631 ubiquitin conjugating enzyme activity 2/1236 35/18639 0.0571428571428571 0.861719833564494 0.684519431307155 0.889257225925835 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:0004549 tRNA-specific ribonuclease activity 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:0004659 prenyltransferase activity 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:0008484 sulfuric ester hydrolase activity 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:0015278 intracellularly gated calcium channel activity 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:0016018 cyclosporin A binding 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:0031489 myosin V binding 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:0046965 nuclear retinoid X receptor binding 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:0051787 misfolded protein binding 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:0070492 oligosaccharide binding 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:1901567 fatty acid derivative binding 1/1236 17/18639 0.0588235294117647 0.887064534551685 0.688684671003356 0.889257225925835 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/1236 70/18639 0.0571428571428571 0.861719833564494 0.690618700441046 0.890741164773395 GO:0004864 protein phosphatase inhibitor activity 3/1236 53/18639 0.0566037735849057 0.853590401172376 0.691769540498464 0.890772744596651 GO:0008081 phosphoric diester hydrolase activity 5/1236 87/18639 0.0574712643678161 0.866672246401071 0.692212828840746 0.890772744596651 GO:0141108 transporter regulator activity 10/1236 170/18639 0.0588235294117647 0.887064534551685 0.697513807198237 0.89657777029445 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/1236 36/18639 0.0555555555555556 0.837783171521036 0.699462484820773 0.897050757369014 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/1236 36/18639 0.0555555555555556 0.837783171521036 0.699462484820773 0.897050757369014 GO:0000900 mRNA regulatory element binding translation repressor activity 1/1236 18/18639 0.0555555555555556 0.837783171521036 0.709347636669764 0.903602208327926 GO:0004706 JUN kinase kinase kinase activity 1/1236 18/18639 0.0555555555555556 0.837783171521036 0.709347636669764 0.903602208327926 GO:0008525 phosphatidylcholine transporter activity 1/1236 18/18639 0.0555555555555556 0.837783171521036 0.709347636669764 0.903602208327926 GO:0016854 racemase and epimerase activity 1/1236 18/18639 0.0555555555555556 0.837783171521036 0.709347636669764 0.903602208327926 GO:0031690 adrenergic receptor binding 1/1236 18/18639 0.0555555555555556 0.837783171521036 0.709347636669764 0.903602208327926 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/1236 18/18639 0.0555555555555556 0.837783171521036 0.709347636669764 0.903602208327926 GO:0030551 cyclic nucleotide binding 2/1236 37/18639 0.0540540540540541 0.815140383101548 0.713812938700269 0.907253847060252 GO:0042805 actinin binding 2/1236 37/18639 0.0540540540540541 0.815140383101548 0.713812938700269 0.907253847060252 GO:0004521 RNA endonuclease activity 4/1236 73/18639 0.0547945205479452 0.826306689719378 0.721870065241472 0.90876009546373 GO:0005516 calmodulin binding 12/1236 207/18639 0.0579710144927536 0.874208526804559 0.725966541135273 0.90876009546373 GO:0019212 phosphatase inhibitor activity 3/1236 56/18639 0.0535714285714286 0.807862343966713 0.727130452247297 0.90876009546373 GO:0170055 lipid transmembrane transporter activity 3/1236 56/18639 0.0535714285714286 0.807862343966713 0.727130452247297 0.90876009546373 GO:0005501 retinoid binding 2/1236 38/18639 0.0526315789473684 0.793689320388349 0.72758360743097 0.90876009546373 GO:0019840 isoprenoid binding 2/1236 38/18639 0.0526315789473684 0.793689320388349 0.72758360743097 0.90876009546373 GO:0042887 amide transmembrane transporter activity 2/1236 38/18639 0.0526315789473684 0.793689320388349 0.72758360743097 0.90876009546373 GO:0008574 plus-end-directed microtubule motor activity 1/1236 19/18639 0.0526315789473684 0.793689320388349 0.72864017311121 0.90876009546373 GO:0015245 fatty acid transmembrane transporter activity 1/1236 19/18639 0.0526315789473684 0.793689320388349 0.72864017311121 0.90876009546373 GO:0022821 solute:potassium antiporter activity 1/1236 19/18639 0.0526315789473684 0.793689320388349 0.72864017311121 0.90876009546373 GO:0030506 ankyrin binding 1/1236 19/18639 0.0526315789473684 0.793689320388349 0.72864017311121 0.90876009546373 GO:0031420 alkali metal ion binding 1/1236 19/18639 0.0526315789473684 0.793689320388349 0.72864017311121 0.90876009546373 GO:0034987 immunoglobulin receptor binding 1/1236 19/18639 0.0526315789473684 0.793689320388349 0.72864017311121 0.90876009546373 GO:0042800 histone H3K4 methyltransferase activity 1/1236 19/18639 0.0526315789473684 0.793689320388349 0.72864017311121 0.90876009546373 GO:0042834 peptidoglycan binding 1/1236 19/18639 0.0526315789473684 0.793689320388349 0.72864017311121 0.90876009546373 GO:0046527 glucosyltransferase activity 1/1236 19/18639 0.0526315789473684 0.793689320388349 0.72864017311121 0.90876009546373 GO:0120227 acyl-CoA binding 1/1236 19/18639 0.0526315789473684 0.793689320388349 0.72864017311121 0.90876009546373 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 5/1236 91/18639 0.0549450549450549 0.828576763042782 0.729410085433884 0.90876009546373 GO:0000217 DNA secondary structure binding 2/1236 39/18639 0.0512820512820513 0.773338312173264 0.740788212452425 0.920142531365034 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/1236 39/18639 0.0512820512820513 0.773338312173264 0.740788212452425 0.920142531365034 GO:0005126 cytokine receptor binding 16/1236 275/18639 0.0581818181818182 0.87738746690203 0.741738169088048 0.920142531365034 GO:0001972 retinoic acid binding 1/1236 20/18639 0.05 0.754004854368932 0.746653102543785 0.920142531365034 GO:0010851 cyclase regulator activity 1/1236 20/18639 0.05 0.754004854368932 0.746653102543785 0.920142531365034 GO:0016408 C-acyltransferase activity 1/1236 20/18639 0.05 0.754004854368932 0.746653102543785 0.920142531365034 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1236 20/18639 0.05 0.754004854368932 0.746653102543785 0.920142531365034 GO:0030742 GTP-dependent protein binding 1/1236 20/18639 0.05 0.754004854368932 0.746653102543785 0.920142531365034 GO:0031418 L-ascorbic acid binding 1/1236 20/18639 0.05 0.754004854368932 0.746653102543785 0.920142531365034 GO:0052745 inositol phosphate phosphatase activity 1/1236 20/18639 0.05 0.754004854368932 0.746653102543785 0.920142531365034 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 7/1236 128/18639 0.0546875 0.824692809466019 0.752576446302515 0.925493255978314 GO:0032451 demethylase activity 2/1236 40/18639 0.05 0.754004854368932 0.753441205747984 0.925493255978314 GO:0071855 neuropeptide receptor binding 2/1236 40/18639 0.05 0.754004854368932 0.753441205747984 0.925493255978314 GO:0001217 DNA-binding transcription repressor activity 16/1236 278/18639 0.0575539568345324 0.867919256827548 0.756734174581864 0.928533284486935 GO:0004879 nuclear receptor activity 3/1236 59/18639 0.0508474576271186 0.766784597663321 0.759229842355815 0.929585621438889 GO:0015459 potassium channel regulator activity 3/1236 59/18639 0.0508474576271186 0.766784597663321 0.759229842355815 0.929585621438889 GO:0004867 serine-type endopeptidase inhibitor activity 5/1236 95/18639 0.0526315789473684 0.793689320388349 0.763244030227457 0.930762458761569 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/1236 21/18639 0.0476190476190476 0.718099861303745 0.763471232693411 0.930762458761569 GO:0008373 sialyltransferase activity 1/1236 21/18639 0.0476190476190476 0.718099861303745 0.763471232693411 0.930762458761569 GO:0010314 phosphatidylinositol-5-phosphate binding 1/1236 21/18639 0.0476190476190476 0.718099861303745 0.763471232693411 0.930762458761569 GO:0017080 sodium channel regulator activity 2/1236 41/18639 0.0487804878048781 0.735614492067251 0.765557612810254 0.932304603583303 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/1236 60/18639 0.05 0.754004854368932 0.769227145465723 0.934767462637683 GO:0098531 ligand-modulated transcription factor activity 3/1236 60/18639 0.05 0.754004854368932 0.769227145465723 0.934767462637683 GO:0019894 kinesin binding 2/1236 42/18639 0.0476190476190476 0.718099861303745 0.777152893191746 0.941812791998344 GO:0015026 coreceptor activity 3/1236 61/18639 0.0491803278688525 0.741644119051409 0.778882831236892 0.941812791998344 GO:0008649 rRNA methyltransferase activity 1/1236 22/18639 0.0454545454545455 0.685458958517211 0.77917375478982 0.941812791998344 GO:0033691 sialic acid binding 1/1236 22/18639 0.0454545454545455 0.685458958517211 0.77917375478982 0.941812791998344 GO:0050321 tau-protein kinase activity 1/1236 22/18639 0.0454545454545455 0.685458958517211 0.77917375478982 0.941812791998344 GO:0005201 extracellular matrix structural constituent 9/1236 168/18639 0.0535714285714286 0.807862343966713 0.790634482219159 0.942471012868413 GO:0008514 organic anion transmembrane transporter activity 15/1236 269/18639 0.0557620817843866 0.840897607102898 0.791937842106086 0.942471012868413 GO:0033192 calmodulin-dependent protein phosphatase activity 4/1236 81/18639 0.0493827160493827 0.744696152463143 0.793602888288463 0.942471012868413 GO:0140791 histone H2AXS140 phosphatase activity 4/1236 81/18639 0.0493827160493827 0.744696152463143 0.793602888288463 0.942471012868413 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 4/1236 81/18639 0.0493827160493827 0.744696152463143 0.793602888288463 0.942471012868413 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 4/1236 81/18639 0.0493827160493827 0.744696152463143 0.793602888288463 0.942471012868413 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 4/1236 81/18639 0.0493827160493827 0.744696152463143 0.793602888288463 0.942471012868413 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 4/1236 81/18639 0.0493827160493827 0.744696152463143 0.793602888288463 0.942471012868413 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 4/1236 81/18639 0.0493827160493827 0.744696152463143 0.793602888288463 0.942471012868413 GO:1990439 MAP kinase serine/threonine phosphatase activity 4/1236 81/18639 0.0493827160493827 0.744696152463143 0.793602888288463 0.942471012868413 GO:0003887 DNA-directed DNA polymerase activity 1/1236 23/18639 0.0434782608695652 0.655656395103419 0.793834615244231 0.942471012868413 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/1236 23/18639 0.0434782608695652 0.655656395103419 0.793834615244231 0.942471012868413 GO:0016493 C-C chemokine receptor activity 1/1236 23/18639 0.0434782608695652 0.655656395103419 0.793834615244231 0.942471012868413 GO:0042171 lysophosphatidic acid acyltransferase activity 1/1236 23/18639 0.0434782608695652 0.655656395103419 0.793834615244231 0.942471012868413 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1236 23/18639 0.0434782608695652 0.655656395103419 0.793834615244231 0.942471012868413 GO:0071617 lysophospholipid acyltransferase activity 1/1236 23/18639 0.0434782608695652 0.655656395103419 0.793834615244231 0.942471012868413 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/1236 23/18639 0.0434782608695652 0.655656395103419 0.793834615244231 0.942471012868413 GO:1990782 protein tyrosine kinase binding 6/1236 117/18639 0.0512820512820513 0.773338312173264 0.795917361711147 0.943956327630253 GO:0046982 protein heterodimerization activity 21/1236 369/18639 0.0569105691056911 0.858216907411793 0.796856218522702 0.94408330691364 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 4/1236 82/18639 0.0487804878048781 0.735614492067251 0.8014278740437 0.94752149691625 GO:0033549 MAP kinase phosphatase activity 4/1236 82/18639 0.0487804878048781 0.735614492067251 0.8014278740437 0.94752149691625 GO:0005315 phosphate transmembrane transporter activity 1/1236 24/18639 0.0416666666666667 0.628337378640777 0.807522862749503 0.947602928509023 GO:0019957 C-C chemokine binding 1/1236 24/18639 0.0416666666666667 0.628337378640777 0.807522862749503 0.947602928509023 GO:0030215 semaphorin receptor binding 1/1236 24/18639 0.0416666666666667 0.628337378640777 0.807522862749503 0.947602928509023 GO:0035035 histone acetyltransferase binding 1/1236 24/18639 0.0416666666666667 0.628337378640777 0.807522862749503 0.947602928509023 GO:0050431 transforming growth factor beta binding 1/1236 24/18639 0.0416666666666667 0.628337378640777 0.807522862749503 0.947602928509023 GO:0050699 WW domain binding 1/1236 24/18639 0.0416666666666667 0.628337378640777 0.807522862749503 0.947602928509023 GO:0140612 DNA damage sensor activity 1/1236 24/18639 0.0416666666666667 0.628337378640777 0.807522862749503 0.947602928509023 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 4/1236 83/18639 0.0481927710843374 0.726751666861621 0.809010782136778 0.947602928509023 GO:0030165 PDZ domain binding 4/1236 83/18639 0.0481927710843374 0.726751666861621 0.809010782136778 0.947602928509023 GO:0017018 myosin phosphatase activity 4/1236 84/18639 0.0476190476190476 0.718099861303745 0.816355712943372 0.950044769086062 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/1236 46/18639 0.0434782608695652 0.655656395103419 0.818640608581227 0.950044769086062 GO:0030276 clathrin binding 2/1236 46/18639 0.0434782608695652 0.655656395103419 0.818640608581227 0.950044769086062 GO:0030291 protein serine/threonine kinase inhibitor activity 2/1236 46/18639 0.0434782608695652 0.655656395103419 0.818640608581227 0.950044769086062 GO:0004709 MAP kinase kinase kinase activity 1/1236 25/18639 0.04 0.603203883495146 0.820302972426732 0.950044769086062 GO:0008139 nuclear localization sequence binding 1/1236 25/18639 0.04 0.603203883495146 0.820302972426732 0.950044769086062 GO:0015645 fatty acid ligase activity 1/1236 25/18639 0.04 0.603203883495146 0.820302972426732 0.950044769086062 GO:0015662 P-type ion transporter activity 1/1236 25/18639 0.04 0.603203883495146 0.820302972426732 0.950044769086062 GO:0042974 nuclear retinoic acid receptor binding 1/1236 25/18639 0.04 0.603203883495146 0.820302972426732 0.950044769086062 GO:0120515 fatty acid-CoA ligase activity 1/1236 25/18639 0.04 0.603203883495146 0.820302972426732 0.950044769086062 GO:0140358 P-type transmembrane transporter activity 1/1236 25/18639 0.04 0.603203883495146 0.820302972426732 0.950044769086062 GO:0140767 enzyme-substrate adaptor activity 7/1236 139/18639 0.0503597122302158 0.759429349724104 0.82259148465344 0.951724092845723 GO:0001637 G protein-coupled chemoattractant receptor activity 1/1236 26/18639 0.0384615384615385 0.580003734129948 0.832235148535067 0.95190246919568 GO:0004435 phosphatidylinositol phospholipase C activity 1/1236 26/18639 0.0384615384615385 0.580003734129948 0.832235148535067 0.95190246919568 GO:0004950 chemokine receptor activity 1/1236 26/18639 0.0384615384615385 0.580003734129948 0.832235148535067 0.95190246919568 GO:0005112 Notch binding 1/1236 26/18639 0.0384615384615385 0.580003734129948 0.832235148535067 0.95190246919568 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/1236 26/18639 0.0384615384615385 0.580003734129948 0.832235148535067 0.95190246919568 GO:0008143 poly(A) binding 1/1236 26/18639 0.0384615384615385 0.580003734129948 0.832235148535067 0.95190246919568 GO:0030507 spectrin binding 1/1236 26/18639 0.0384615384615385 0.580003734129948 0.832235148535067 0.95190246919568 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/1236 48/18639 0.0416666666666667 0.628337378640777 0.83667309368494 0.95190246919568 GO:0140693 molecular condensate scaffold activity 2/1236 48/18639 0.0416666666666667 0.628337378640777 0.83667309368494 0.95190246919568 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/1236 27/18639 0.037037037037037 0.558522114347357 0.843375607161331 0.95190246919568 GO:0005385 zinc ion transmembrane transporter activity 1/1236 27/18639 0.037037037037037 0.558522114347357 0.843375607161331 0.95190246919568 GO:0016405 CoA-ligase activity 1/1236 27/18639 0.037037037037037 0.558522114347357 0.843375607161331 0.95190246919568 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/1236 27/18639 0.037037037037037 0.558522114347357 0.843375607161331 0.95190246919568 GO:0005004 GPI-linked ephrin receptor activity 2/1236 49/18639 0.0408163265306122 0.615514166831781 0.845067246905184 0.95190246919568 GO:0005008 hepatocyte growth factor receptor activity 2/1236 49/18639 0.0408163265306122 0.615514166831781 0.845067246905184 0.95190246919568 GO:0005009 insulin receptor activity 2/1236 49/18639 0.0408163265306122 0.615514166831781 0.845067246905184 0.95190246919568 GO:0005011 macrophage colony-stimulating factor receptor activity 2/1236 49/18639 0.0408163265306122 0.615514166831781 0.845067246905184 0.95190246919568 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/1236 49/18639 0.0408163265306122 0.615514166831781 0.845067246905184 0.95190246919568 GO:0005020 stem cell factor receptor activity 2/1236 49/18639 0.0408163265306122 0.615514166831781 0.845067246905184 0.95190246919568 GO:0008288 boss receptor activity 2/1236 49/18639 0.0408163265306122 0.615514166831781 0.845067246905184 0.95190246919568 GO:0035254 glutamate receptor binding 2/1236 49/18639 0.0408163265306122 0.615514166831781 0.845067246905184 0.95190246919568 GO:0036332 placental growth factor receptor activity 2/1236 49/18639 0.0408163265306122 0.615514166831781 0.845067246905184 0.95190246919568 GO:0038062 protein tyrosine kinase collagen receptor activity 2/1236 49/18639 0.0408163265306122 0.615514166831781 0.845067246905184 0.95190246919568 GO:0060175 brain-derived neurotrophic factor receptor activity 2/1236 49/18639 0.0408163265306122 0.615514166831781 0.845067246905184 0.95190246919568 GO:0016758 hexosyltransferase activity 10/1236 197/18639 0.050761421319797 0.76548716179587 0.848672781878215 0.95190246919568 GO:0016782 transferase activity, transferring sulphur-containing groups 3/1236 70/18639 0.0428571428571429 0.64628987517337 0.851547183760227 0.95190246919568 GO:0005006 epidermal growth factor receptor activity 2/1236 50/18639 0.04 0.603203883495146 0.85306746794835 0.95190246919568 GO:0005007 fibroblast growth factor receptor activity 2/1236 50/18639 0.04 0.603203883495146 0.85306746794835 0.95190246919568 GO:0005017 platelet-derived growth factor receptor activity 2/1236 50/18639 0.04 0.603203883495146 0.85306746794835 0.95190246919568 GO:0005019 platelet-derived growth factor beta-receptor activity 2/1236 50/18639 0.04 0.603203883495146 0.85306746794835 0.95190246919568 GO:0032813 tumor necrosis factor receptor superfamily binding 2/1236 50/18639 0.04 0.603203883495146 0.85306746794835 0.95190246919568 GO:0008194 UDP-glycosyltransferase activity 7/1236 145/18639 0.0482758620689655 0.7280046869769 0.853674888739749 0.95190246919568 GO:0005242 inward rectifier potassium channel activity 1/1236 28/18639 0.0357142857142857 0.538574895977809 0.853776840212513 0.95190246919568 GO:0045499 chemorepellent activity 1/1236 28/18639 0.0357142857142857 0.538574895977809 0.853776840212513 0.95190246919568 GO:0050698 proteoglycan sulfotransferase activity 1/1236 28/18639 0.0357142857142857 0.538574895977809 0.853776840212513 0.95190246919568 GO:0051393 alpha-actinin binding 1/1236 28/18639 0.0357142857142857 0.538574895977809 0.853776840212513 0.95190246919568 GO:0141052 histone H3 demethylase activity 1/1236 28/18639 0.0357142857142857 0.538574895977809 0.853776840212513 0.95190246919568 GO:0004620 phospholipase activity 5/1236 109/18639 0.0458715596330275 0.691747572815534 0.856610402582988 0.953364516838181 GO:0015293 symporter activity 7/1236 146/18639 0.0479452054794521 0.723018353504455 0.858400464100274 0.953364516838181 GO:0005010 insulin-like growth factor receptor activity 2/1236 51/18639 0.0392156862745098 0.59137635636779 0.860689038978625 0.953364516838181 GO:0005021 vascular endothelial growth factor receptor activity 2/1236 51/18639 0.0392156862745098 0.59137635636779 0.860689038978625 0.953364516838181 GO:0005030 neurotrophin receptor activity 2/1236 51/18639 0.0392156862745098 0.59137635636779 0.860689038978625 0.953364516838181 GO:0016830 carbon-carbon lyase activity 2/1236 51/18639 0.0392156862745098 0.59137635636779 0.860689038978625 0.953364516838181 GO:0016829 lyase activity 10/1236 200/18639 0.05 0.754004854368932 0.861008715401758 0.953364516838181 GO:0004629 phospholipase C activity 1/1236 29/18639 0.0344827586206897 0.520003347840643 0.863487861946828 0.953364516838181 GO:0099604 ligand-gated calcium channel activity 1/1236 29/18639 0.0344827586206897 0.520003347840643 0.863487861946828 0.953364516838181 GO:0106222 lncRNA binding 1/1236 29/18639 0.0344827586206897 0.520003347840643 0.863487861946828 0.953364516838181 GO:0005096 GTPase activator activity 14/1236 271/18639 0.0516605166051661 0.77904560599004 0.866403639132986 0.954770586029334 GO:0030159 signaling receptor complex adaptor activity 2/1236 52/18639 0.0384615384615385 0.580003734129948 0.867946949379559 0.954770586029334 GO:0016298 lipase activity 6/1236 130/18639 0.0461538461538462 0.696004480955937 0.868907946000232 0.954770586029334 GO:0016798 hydrolase activity, acting on glycosyl bonds 6/1236 130/18639 0.0461538461538462 0.696004480955937 0.868907946000232 0.954770586029334 GO:0016769 transferase activity, transferring nitrogenous groups 1/1236 30/18639 0.0333333333333333 0.502669902912621 0.872554439197431 0.954770586029334 GO:0031624 ubiquitin conjugating enzyme binding 1/1236 30/18639 0.0333333333333333 0.502669902912621 0.872554439197431 0.954770586029334 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/1236 30/18639 0.0333333333333333 0.502669902912621 0.872554439197431 0.954770586029334 GO:0070566 adenylyltransferase activity 1/1236 30/18639 0.0333333333333333 0.502669902912621 0.872554439197431 0.954770586029334 GO:0005003 ephrin receptor activity 2/1236 53/18639 0.0377358490566038 0.569060267448251 0.874855867374896 0.954770586029334 GO:0005005 transmembrane-ephrin receptor activity 2/1236 53/18639 0.0377358490566038 0.569060267448251 0.874855867374896 0.954770586029334 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/1236 53/18639 0.0377358490566038 0.569060267448251 0.874855867374896 0.954770586029334 GO:0038064 collagen receptor activity 2/1236 53/18639 0.0377358490566038 0.569060267448251 0.874855867374896 0.954770586029334 GO:0005184 neuropeptide hormone activity 1/1236 31/18639 0.032258064516129 0.48645474475415 0.881019306366649 0.959651547721829 GO:0005452 solute:inorganic anion antiporter activity 1/1236 31/18639 0.032258064516129 0.48645474475415 0.881019306366649 0.959651547721829 GO:0046943 carboxylic acid transmembrane transporter activity 9/1236 188/18639 0.0478723404255319 0.721919541417063 0.882891976219922 0.960769312569138 GO:0005342 organic acid transmembrane transporter activity 9/1236 189/18639 0.0476190476190476 0.718099861303745 0.886457127339705 0.962716493925631 GO:0004896 cytokine receptor activity 4/1236 96/18639 0.0416666666666667 0.628337378640777 0.887593672987993 0.962716493925631 GO:0008378 galactosyltransferase activity 1/1236 32/18639 0.03125 0.471253033980583 0.888922366197411 0.962716493925631 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/1236 32/18639 0.03125 0.471253033980583 0.888922366197411 0.962716493925631 GO:0160041 neuropeptide activity 1/1236 32/18639 0.03125 0.471253033980583 0.888922366197411 0.962716493925631 GO:0140416 transcription regulator inhibitor activity 1/1236 33/18639 0.0303030303030303 0.456972639011474 0.896300877262064 0.969782169392224 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/1236 34/18639 0.0294117647058824 0.443532267275842 0.903189629046655 0.972632273183284 GO:0016831 carboxy-lyase activity 1/1236 34/18639 0.0294117647058824 0.443532267275842 0.903189629046655 0.972632273183284 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/1236 34/18639 0.0294117647058824 0.443532267275842 0.903189629046655 0.972632273183284 GO:0061980 regulatory RNA binding 2/1236 58/18639 0.0344827586206897 0.520003347840643 0.90465389849925 0.972632273183284 GO:0016757 glycosyltransferase activity 13/1236 267/18639 0.048689138576779 0.73423693683866 0.906351018350487 0.972632273183284 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 13/1236 268/18639 0.0485074626865672 0.73149724677583 0.908915593101341 0.972632273183284 GO:0005154 epidermal growth factor receptor binding 1/1236 35/18639 0.0285714285714286 0.430859916782247 0.909621105450757 0.972632273183284 GO:0005343 organic acid:sodium symporter activity 1/1236 35/18639 0.0285714285714286 0.430859916782247 0.909621105450757 0.972632273183284 GO:0016229 steroid dehydrogenase activity 1/1236 35/18639 0.0285714285714286 0.430859916782247 0.909621105450757 0.972632273183284 GO:0140566 histone reader activity 1/1236 35/18639 0.0285714285714286 0.430859916782247 0.909621105450757 0.972632273183284 GO:0036002 pre-mRNA binding 2/1236 59/18639 0.0338983050847458 0.511189731775547 0.909756496960423 0.972632273183284 GO:0070888 E-box binding 2/1236 59/18639 0.0338983050847458 0.511189731775547 0.909756496960423 0.972632273183284 GO:0015108 chloride transmembrane transporter activity 5/1236 121/18639 0.0413223140495868 0.623144507742919 0.910075307595284 0.972632273183284 GO:0005125 cytokine activity 11/1236 234/18639 0.047008547008547 0.708893452825492 0.913491906438671 0.974587628160249 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 5/1236 122/18639 0.040983606557377 0.618036765876174 0.913622234680621 0.974587628160249 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/1236 60/18639 0.0333333333333333 0.502669902912621 0.914602336667137 0.974717044241503 GO:0008083 growth factor activity 7/1236 162/18639 0.0432098765432099 0.65160913340525 0.918420564006433 0.977514491806879 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 8/1236 181/18639 0.0441988950276243 0.666523628171432 0.918949746923295 0.977514491806879 GO:0022829 wide pore channel activity 1/1236 37/18639 0.027027027027027 0.407570191550774 0.921231545767882 0.978108329697424 GO:0030280 structural constituent of skin epidermis 1/1236 37/18639 0.027027027027027 0.407570191550774 0.921231545767882 0.978108329697424 GO:0015179 L-amino acid transmembrane transporter activity 2/1236 62/18639 0.032258064516129 0.48645474475415 0.923569655509912 0.979674354209112 GO:0005109 frizzled binding 1/1236 38/18639 0.0263157894736842 0.396844660194175 0.926465273831041 0.980404420947457 GO:0004497 monooxygenase activity 4/1236 106/18639 0.0377358490566038 0.569060267448251 0.92719837294123 0.980404420947457 GO:0008013 beta-catenin binding 4/1236 106/18639 0.0377358490566038 0.569060267448251 0.92719837294123 0.980404420947457 GO:1901682 sulfur compound transmembrane transporter activity 2/1236 63/18639 0.0317460317460317 0.478733240869163 0.92771308202429 0.980404420947457 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/1236 39/18639 0.0256410256410256 0.386669156086632 0.931351512288373 0.983333922276562 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/1236 40/18639 0.025 0.377002427184466 0.935913315020178 0.987231981921842 GO:0004222 metalloendopeptidase activity 4/1236 110/18639 0.0363636363636364 0.548367166813769 0.939153361920794 0.989729866091088 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/1236 41/18639 0.024390243902439 0.367807246033625 0.940172207575426 0.989884467159656 GO:0016500 protein-hormone receptor activity 2/1236 67/18639 0.0298507462686567 0.450152151862049 0.942256105152545 0.990854748562009 GO:0005179 hormone activity 5/1236 132/18639 0.0378787878787879 0.571215798764342 0.942839760746229 0.990854748562009 GO:0035198 miRNA binding 1/1236 42/18639 0.0238095238095238 0.359049930651872 0.944148288414053 0.991312032701156 GO:0003777 microtubule motor activity 2/1236 68/18639 0.0294117647058824 0.443532267275842 0.945431231506885 0.99174163378957 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/1236 43/18639 0.0232558139534884 0.35069993226462 0.947860323447673 0.993371622449777 GO:0001223 transcription coactivator binding 1/1236 44/18639 0.0227272727272727 0.342729479258605 0.951325834321983 0.995165734521153 GO:0043014 alpha-tubulin binding 1/1236 44/18639 0.0227272727272727 0.342729479258605 0.951325834321983 0.995165734521153 GO:0042562 hormone binding 3/1236 94/18639 0.0319148936170213 0.481279694278042 0.953388907405585 0.995796820101302 GO:0140299 molecular sensor activity 2/1236 71/18639 0.028169014084507 0.424791467250103 0.953988349012244 0.995796820101302 GO:0140303 intramembrane lipid transporter activity 1/1236 45/18639 0.0222222222222222 0.335113268608414 0.954561180854816 0.995796820101302 GO:0099106 ion channel regulator activity 6/1236 160/18639 0.0375 0.565503640776699 0.958494325622615 0.998981689239365 GO:0099095 ligand-gated monoatomic anion channel activity 1/1236 47/18639 0.0212765957446809 0.320853129518694 0.960401467813239 0.999999996833171 GO:0016755 aminoacyltransferase activity 24/1236 496/18639 0.0483870967741935 0.729682117131225 0.962086539425722 0.999999996833171 GO:0019787 ubiquitin-like protein transferase activity 23/1236 479/18639 0.0480167014613779 0.724096519853254 0.962711380863553 0.999999996833171 GO:0061659 ubiquitin-like protein ligase activity 17/1236 372/18639 0.0456989247311828 0.689144221735045 0.963187359070655 0.999999996833171 GO:0019199 transmembrane receptor protein kinase activity 2/1236 78/18639 0.0256410256410256 0.386669156086632 0.969244263433157 0.999999996833171 GO:0008509 monoatomic anion transmembrane transporter activity 5/1236 149/18639 0.0335570469798658 0.506043526422102 0.972754265864335 0.999999996833171 GO:0008146 sulfotransferase activity 1/1236 53/18639 0.0188679245283019 0.284530133724125 0.973794327168103 0.999999996833171 GO:0017046 peptide hormone binding 1/1236 53/18639 0.0188679245283019 0.284530133724125 0.973794327168103 0.999999996833171 GO:0000149 SNARE binding 3/1236 106/18639 0.0283018867924528 0.426795200586188 0.974888642188142 0.999999996833171 GO:0140463 chromatin-protein adaptor activity 1/1236 54/18639 0.0185185185185185 0.279261057173678 0.975537048120445 0.999999996833171 GO:0061630 ubiquitin protein ligase activity 15/1236 353/18639 0.0424929178470255 0.640797326659149 0.978568262129098 0.999999996833171 GO:0019905 syntaxin binding 1/1236 61/18639 0.0163934426229508 0.24721470635047 0.984890257518709 0.999999996833171 GO:0015103 inorganic anion transmembrane transporter activity 5/1236 165/18639 0.0303030303030303 0.456972639011474 0.98694398066004 0.999999996833171 GO:0008528 G protein-coupled peptide receptor activity 3/1236 122/18639 0.0245901639344262 0.370822059525704 0.989321227795061 0.999999996833171 GO:0015085 calcium ion transmembrane transporter activity 4/1236 147/18639 0.0272108843537415 0.410342777887854 0.989742892232491 0.999999996833171 GO:0019842 vitamin binding 4/1236 150/18639 0.0266666666666667 0.402135922330097 0.991191841332031 0.999999996833171 GO:0098960 postsynaptic neurotransmitter receptor activity 1/1236 69/18639 0.0144927536231884 0.21855213170114 0.991290119726937 0.999999996833171 GO:0001653 peptide receptor activity 3/1236 128/18639 0.0234375 0.353439775485437 0.992308977948643 0.999999996833171 GO:0015171 amino acid transmembrane transporter activity 2/1236 102/18639 0.0196078431372549 0.295688178183895 0.992580544389884 0.999999996833171 GO:0005262 calcium channel activity 3/1236 131/18639 0.0229007633587786 0.345345734825465 0.99348194368846 0.999999996833171 GO:0004842 ubiquitin-protein transferase activity 18/1236 449/18639 0.0400890868596882 0.604547321988453 0.993926685110102 0.999999996833171 GO:0015079 potassium ion transmembrane transporter activity 4/1236 160/18639 0.025 0.377002427184466 0.994735366108573 0.999999996833171 GO:0015370 solute:sodium symporter activity 1/1236 79/18639 0.0126582278481013 0.190887304903527 0.995626732914491 0.999999996833171 GO:0070851 growth factor receptor binding 3/1236 139/18639 0.0215827338129496 0.32546972131033 0.995824904015978 0.999999996833171 GO:0015101 organic cation transmembrane transporter activity 1/1236 81/18639 0.0123456790123457 0.186174038115786 0.9961898266214 0.999999996833171 GO:0005254 chloride channel activity 1/1236 83/18639 0.0120481927710843 0.181687916715405 0.996680468484769 0.999999996833171 GO:0003730 mRNA 3'-UTR binding 8/1236 262/18639 0.0305343511450382 0.460460979767287 0.996737684760584 0.999999996833171 GO:0005261 monoatomic cation channel activity 11/1236 341/18639 0.032258064516129 0.48645474475415 0.998216449766748 0.999999996833171 GO:0015276 ligand-gated monoatomic ion channel activity 4/1236 186/18639 0.021505376344086 0.324303163169433 0.998678645161313 0.999999996833171 GO:0030594 neurotransmitter receptor activity 1/1236 97/18639 0.0103092783505155 0.155464918426584 0.998735805011077 0.999999996833171 GO:0022834 ligand-gated channel activity 4/1236 188/18639 0.0212765957446809 0.320853129518694 0.998814703603602 0.999999996833171 GO:0005249 voltage-gated potassium channel activity 1/1236 98/18639 0.0102040816326531 0.153878541707945 0.998820075586329 0.999999996833171 GO:0015081 sodium ion transmembrane transporter activity 3/1236 164/18639 0.0182926829268293 0.275855434525219 0.998996735706398 0.999999996833171 GO:0099094 ligand-gated monoatomic cation channel activity 2/1236 136/18639 0.0147058823529412 0.221766133637921 0.99908183473378 0.999999996833171 GO:0005253 monoatomic anion channel activity 1/1236 103/18639 0.00970873786407767 0.1464087095862 0.999164339830052 0.999999996833171 GO:0001216 DNA-binding transcription activator activity 16/1236 491/18639 0.0325865580448065 0.491408459059182 0.999703068268134 0.999999996833171 GO:0046873 metal ion transmembrane transporter activity 14/1236 450/18639 0.0311111111111111 0.46915857605178 0.999721831291268 0.999999996833171 GO:0005267 potassium channel activity 1/1236 124/18639 0.00806451612903226 0.121613686188537 0.999803975824663 0.999999996833171 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 15/1236 484/18639 0.0309917355371901 0.467358380807189 0.999834538928732 0.999999996833171 GO:0005216 monoatomic ion channel activity 13/1236 448/18639 0.0290178571428571 0.43759210298197 0.999881030369091 0.999999996833171 GO:0005244 voltage-gated monoatomic ion channel activity 2/1236 173/18639 0.0115606936416185 0.174336382513048 0.999911387537544 0.999999996833171 GO:0022832 voltage-gated channel activity 2/1236 175/18639 0.0114285714285714 0.172343966712899 0.999922019439539 0.999999996833171 GO:0022843 voltage-gated monoatomic cation channel activity 1/1236 143/18639 0.00699300699300699 0.105455224387263 0.999947286069836 0.999999996833171 GO:0045182 translation regulator activity 7/1236 356/18639 0.0196629213483146 0.296518762954074 0.999990311083663 0.999999996833171 GO:0022836 gated channel activity 5/1236 318/18639 0.0157232704402516 0.237108444770104 0.999996234433685 0.999999996833171 GO:0030371 translation repressor activity 2/1236 329/18639 0.0060790273556231 0.091672322719627 0.999999996833171 0.999999996833171