category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	73/145	238/9376	19.8333236742973	RPS12/RPL13/RPS14/RPL10/RPLP1/RPS18/RPS2/RPS8/RPS23/RPS24/RPL18A/RPS3/RPL13A/RPS4X/RPL18/RPL3/RPS19/RPS27A/RPS15/RPL15/RPL32/RPS11/RPL8/RPS13/RPL29/RPL23A/RPL11/RPL19/RPL7A/RPL10A/RPS16/RPLP0/RPS6/RPLP2/RPS5/RPL37A/RPS3A/RPS28/RPL27A/RPL23/RPL7/RPL26/RPS27/RPL35/RPL21/RPL22/RPS20/RPSA/RPL9/RPL35A/RPL6/RPL5/RPL34/RPL24/RPL12/RPS9/RPL14/RPS7/RPS25/RPL31/RPL36/UBA52/RPS15A/RPS29/RPL27/RPL28/RPS26/RPS4Y1/RPL4/C1QA/RPL41/C1QB/CYBB	36.8837556202146
Genetic Information Processing	Translation	hsa03010	Ribosome	71/145	222/9376	20.6802112457285	RPS12/RPL13/RPS14/RPL10/RPLP1/RPS18/RPS2/RPS8/RPS23/RPS24/RPL18A/RPS3/RPL13A/RPS4X/RPL18/RPL3/RPS19/RPS27A/RPS15/RPL15/RPL32/RPS11/RPL8/RPS13/RPL29/RPL23A/RPL11/RPL19/RPL7A/RPL10A/RPS16/RPLP0/RPS6/RPLP2/RPS5/RPL37A/RPS3A/RPS28/RPL27A/RPL23/RPL7/RACK1/RPL26/RPS27/RPL35/RPL21/RPL22/RPS20/RPSA/RPL9/RPL35A/RPL6/RPL5/RPL34/RPL24/RPL12/RPS9/RPL14/RPS7/RPS25/RPL31/RPL36/UBA52/RPS15A/RPS29/RPL27/RPL28/RPS26/RPS4Y1/RPL4/RPL41	37.1917019509403
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	21/145	205/9376	6.62391925988225	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/CYBA/COX4I1/SLC25A6/COX7C/ATP5PF/NDUFS5/MT-ND6/SLC25A5/NDUFA4/COX6C/CYBB	10.203588243225
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	23/145	275/9376	5.40810031347962	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/CYBA/COX4I1/SLC25A6/COX7C/C1QA/ATP5PF/NDUFS5/MT-ND6/SLC25A5/NDUFA4/COX6C/C1QB/CYBB	9.29862048222916
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	17/145	138/9376	7.9656171914043	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/COX4I1/COX7C/ATP5PF/NDUFS5/MT-ND6/NDUFA4/COX6C	10.3313109101657
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	21/145	227/9376	5.98195351663375	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/CYBA/MGST3/COX4I1/SLC25A6/COX7C/ATP5PF/NDUFS5/MT-ND6/SLC25A5/NDUFA4/COX6C	9.52294003726521
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	22/145	268/9376	5.3080802882141	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/RPS27A/UBA52/COX4I1/SLC25A6/COX7C/GNAS/ATP5PF/NDUFS5/MT-ND6/SLC25A5/NDUFA4/COX6C	8.96777985312578
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	20/145	235/9376	5.50315480557594	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/RPS6/COX4I1/COX7C/GNAS/ACTG1/ATP5PF/NDUFS5/MT-ND6/NDUFA4/COX6C	8.76191866743415
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	19/145	308/9376	3.98889386475593	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/COX4I1/SLC25A6/COX7C/ATP5PF/NDUFS5/MT-ND6/SLC25A5/NDUFA4/COX6C	6.68459900436116
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	21/145	388/9376	3.49975115535016	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/APOE/COX4I1/SLC25A6/COX7C/ATP5PF/NDUFS5/MT-ND6/SLC25A5/NDUFA4/COX6C/CYBB	6.30269617954384
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	20/145	368/9376	3.51424287856072	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/PFN1/COX4I1/COX7C/ACTG1/ATP5PF/NDUFS5/MT-ND6/NDUFA4/COX6C/HNRNPA1	6.16683336021369
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	22/145	480/9376	2.96367816091954	MT-CO1/MT-ATP6/MT-CO3/MT-CYB/MT-CO2/MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/RPS27A/UBA52/COX4I1/SLC25A6/COX7C/ATP5PF/NDUFS5/MT-ND6/SLC25A5/NDUFA4/COX6C/CYBB	5.53526994575607
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	7/145	87/9376	5.20269520412208	MT-CO1/MT-CO3/MT-CYB/MT-CO2/COX4I1/COX7C/COX6C	4.93569486793665
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	9/145	157/9376	3.70674280694048	MT-CO1/MT-CO3/MT-CYB/MT-CO2/COX4I1/COX7C/NDUFS5/NDUFA4/COX6C	4.28647380324483
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	8/145	149/9376	3.47178893774589	MT-ND4/MT-ND3/MT-ND1/MT-ND2/MT-ND5/NDUFS5/MT-ND6/NDUFA4	3.8117071078673
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	6/145	142/9376	2.73220009713453	CYBA/GSTP1/CTSL/MGST3/ACTG1/HSP90AB1	2.60670904881287
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	4/145	78/9376	3.31600353669319	EEF1A1/CYBA/HLA-DRA/CYBB	2.57416874270908
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	6/145	155/9376	2.50304783092325	CYBA/CTSL/CORO1A/ACTG1/HLA-DRA/CYBB	2.36480264846444
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	4/145	82/9376	3.1542472666106	CTSL/CD74/HSP90AB1/HLA-DRA	2.4555365706433
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	3/145	52/9376	3.73050397877984	CGA/HSD17B1/GNAS	2.47450660249012
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	3/145	59/9376	3.28790181180596	GSTP1/MGST3/GPX4	2.20938094529383
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	4/145	99/9376	2.61260884709161	KRT18/C1QA/HLA-DRA/C1QB	2.02156691327983
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	4/145	103/9376	2.51114830934047	FN1/PRDX1/GNAS/HSPB1	1.93268393144063
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	5/145	168/9376	1.92446633825944	SLC25A6/PPIA/HSP90AB1/SLC25A5/CYBB	1.51533394371403
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/145	42/9376	3.07914614121511	GPX4/CYBB	1.69247018707336
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	3/145	94/9376	2.06368305209098	S100A9/HSP90AB1/LCN2	1.29897456758358
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	5/145	195/9376	1.6580017683466	CYBA/SLC25A6/ACTG1/SLC25A5/CYBB	1.16370965236021
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	6/145	248/9376	1.56440489432703	RPS3/PFN1/S100A10/ANXA2/ACTG1/HSP90AB1	1.12894831496708
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/145	51/9376	2.53576741041244	GNAS/ACTG1	1.37826072006986
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	2/145	52/9376	2.48700265251989	APOE/PLTP	1.34758927662324
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/145	54/9376	2.3948914431673	CGA/HLA-DRA	1.28833262450063
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	5/145	204/9376	1.58485463150778	FN1/RPS6/CTSL/ACTG1/TIMP3	1.05846440556798
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/145	103/9376	1.88336123200536	GNAS/C1QA/C1QB	1.12977531603067
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	4/145	154/9376	1.6795342588446	RGS2/GNAS/ACTG1/EEF2	1.06562505224981
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	3/145	106/9376	1.83005855562785	GSTP1/FOLR3/HSP90AB1	1.07712736547903
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/145	59/9376	2.19193454120397	CGA/GNAS	1.15102730798351
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	3/145	110/9376	1.76351097178683	RPS6/LDHB/CYBB	1.00951026841083
Organismal Systems	Digestive system	hsa04980	Cobalamin transport and metabolism	1/145	18/9376	3.59233716475096	PRDX1	1.37968989050822
NA	NA	hsa04382	Cornified envelope formation	5/145	217/9376	1.4899094231686	KRT18/S100A9/S100A10/KRT7/KRT8	0.915096499862002
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	4/145	169/9376	1.53046317078147	RPS27A/CTSL/UBA52/VAMP8	0.872137140273143
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/145	65/9376	1.98960212201592	CGA/SPP1	1.00337758929191
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	3/145	116/9376	1.67229488703924	CYBA/ACTG1/CYBB	0.913121510162814
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	4/145	173/9376	1.4950767390871	SLC25A6/ACTG1/SLC25A5/HLA-DRA	0.823713390611443
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	2/145	70/9376	1.84748768472906	GSTP1/MGST3	0.891961595528399
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/145	70/9376	1.84748768472906	ACTG1/HLA-DRA	0.891961595528399
Organismal Systems	Immune system	hsa04611	Platelet activation	3/145	126/9376	1.53957307060755	VAMP8/GNAS/ACTG1	0.764205108479815
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	2/145	73/9376	1.77156353330184	GSTP1/MGST3	0.829405434481822
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/145	75/9376	1.72432183908046	GSTP1/MGST3	0.789301000277097
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	2/145	75/9376	1.72432183908046	CGA/GNAS	0.789301000277097
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	2/145	76/9376	1.7016333938294	GNAS/ACTG1	0.769698847967928
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/145	78/9376	1.6580017683466	FN1/ACTG1	0.731349308362259
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	2/145	78/9376	1.6580017683466	C1QA/C1QB	0.731349308362259
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	2/145	79/9376	1.63701440419031	GSTP1/MGST3	0.7125849517062
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	2/145	82/9376	1.5771236333053	GSTP1/MGST3	0.65783914842486
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/145	139/9376	1.39558422227735	KRT18/GNAS/HSP90AB1	0.588879117320464
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	2/145	83/9376	1.5581221437474	PRDX1/PRDX5	0.640081971605685
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/145	30/9376	2.15540229885057	FOLR3	0.7943762113391
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	3/145	143/9376	1.35654690137449	C1QA/HLA-DRA/C1QB	0.538466303953933
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/145	31/9376	2.08587319243604	TKT	0.75895420142446
NA	NA	hsa04981	Folate transport and metabolism	1/145	31/9376	2.08587319243604	FOLR3	0.75895420142446
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/145	32/9376	2.02068965517241	LDHB	0.724849011978766
Human Diseases	Immune disease	hsa05310	Asthma	1/145	32/9376	2.02068965517241	HLA-DRA	0.724849011978766
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/145	88/9376	1.46959247648903	C1QA/C1QB	0.554685262040879
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/145	89/9376	1.4530802014723	FN1/SPP1	0.538242056765989
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/145	33/9376	1.9594566353187	VAMP8	0.691965449093533
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/145	93/9376	1.39058212829069	CGA/GNAS	0.474411196787795
Organismal Systems	Digestive system	hsa04970	Salivary secretion	2/145	93/9376	1.39058212829069	LYZ/GNAS	0.474411196787795
NA	NA	hsa04518	Integrin signaling	3/145	154/9376	1.25965069413345	FN1/SPP1/ACTG1	0.407176357779385
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/145	95/9376	1.36130671506352	CTSL/HLA-DRA	0.443594051133419
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/145	37/9376	1.74762348555452	HBB	0.571056229956806
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	3/145	157/9376	1.23558093564683	C1QA/CD24/C1QB	0.373072575127834
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/145	39/9376	1.6580017683466	HLA-DRA	0.516060891981826
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/145	100/9376	1.29324137931034	CD24/HLA-DRA	0.369479330041645
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/145	101/9376	1.28043700921816	FN1/CYBB	0.355127511744028
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/145	166/9376	1.16859160781055	SLC25A6/RGS2/SLC25A5	0.274666342982499
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/145	232/9376	1.11486325802616	FN1/TMSB4X/PFN1/ACTG1	0.222025204221674
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/145	105/9376	1.23165845648604	RPS27A/UBA52	0.299174642812278
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/145	105/9376	1.23165845648604	GNAS/ACTG1	0.299174642812278
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/145	170/9376	1.1410953346856	GSTP1/MGST3/ACTG1	0.232673484202888
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	2/145	107/9376	1.20863680309378	LDHB/GNAS	0.272026761399236
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/145	44/9376	1.46959247648903	HLA-DRA	0.39129596301278
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/145	44/9376	1.46959247648903	GNAS	0.39129596301278
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/145	45/9376	1.43693486590038	HLA-DRA	0.36821724755751
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/145	109/9376	1.18645998101867	HSP90AB1/HLA-DRA	0.245400004846416
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/145	47/9376	1.37578870139398	LDHB	0.323683353225858
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	3/145	181/9376	1.07174699942846	CORO1A/CD74/HLA-DRA	0.122155331719236
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/145	49/9376	1.31963406052076	GNAS	0.281141765277775
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/145	50/9376	1.29324137931034	HLA-DRA	0.260560041098598
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/145	50/9376	1.29324137931034	HBB	0.260560041098598
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	4/145	253/9376	1.02232520103585	RPS27A/PFN1/UBA52/ACTG1	0.0451161534729365
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	3/145	187/9376	1.03735939516873	CYBA/HSP90AB1/CYBB	0.0646743061182546
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/145	53/9376	1.22003903708523	GNAS	0.201328423256455
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/145	122/9376	1.0600339174675	CSH1/GNAS	0.083648299284389
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/145	54/9376	1.19744572158365	LDHB	0.182362409584139
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/145	56/9376	1.15467980295566	EEF1A1	0.145500649281417
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/145	200/9376	0.969931034482759	RPS3/ACTG1/NCL	-0.0538706289754621
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/145	60/9376	1.07770114942529	HSPB1	0.0756717177224006
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/145	60/9376	1.07770114942529	GNAS	0.0756717177224006
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/145	203/9376	0.955597078308137	FN1/SPP1/ACTG1	-0.0801584172731006
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/145	134/9376	0.965105506948018	GNAS/CALD1	-0.0509884223111459
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/145	63/9376	1.0263820470717	GPX4	0.0263317199771135
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/145	137/9376	0.94397180971558	CTSL/ACTG1	-0.0827941513247786
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/145	138/9376	0.937131434282859	FN1/ACTG1	-0.0932458217344312
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/145	65/9376	0.994801061007958	GNAS	-0.0052713093036671
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	3/145	212/9376	0.915029277813923	PFN1/GNAS/ACTG1	-0.156833907675676
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/145	140/9376	0.923743842364532	RPS6/SPP1	-0.113931086224494
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/145	66/9376	0.979728317659352	HSD17B1	-0.020712483872383
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/145	66/9376	0.979728317659352	HLA-DRA	-0.020712483872383
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/145	142/9376	0.910733365711511	RPS27A/UBA52	-0.134333293100377
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/145	67/9376	0.965105506948018	LDHB	-0.0359242775683649
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	3/145	216/9376	0.898084291187739	CYBA/HSP90AB1/CYBB	-0.189917739249125
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	2/145	144/9376	0.898084291187739	C1QA/C1QB	-0.154461319766643
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/145	144/9376	0.898084291187739	SLC25A6/SLC25A5	-0.154461319766643
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/145	217/9376	0.89394565390116	MGST3/GNAS/HSP90AB1	-0.198097763220208
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/145	69/9376	0.937131434282859	GNAS	-0.0656898854761968
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/145	69/9376	0.937131434282859	GNAS	-0.0656898854761968
NA	NA	hsa04081	Hormone signaling	3/145	219/9376	0.885781766650921	CSH1/CGA/GNAS	-0.214351315249822
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	5/145	362/9376	0.893122499523719	CSH1/FN1/RPS6/SPP1/HSP90AB1	-0.259912436649566
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/145	71/9376	0.910733365711511	CGA	-0.0946248948466381
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/145	71/9376	0.910733365711511	LDHB	-0.0946248948466381
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	3/145	224/9376	0.866009852216749	SLC25A6/SLC25A5/HLA-DRA	-0.2543806855477
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/145	73/9376	0.885781766650921	PPIA	-0.122780846123243
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/145	75/9376	0.86216091954023	TKT	-0.150204671755157
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/145	76/9376	0.850816696914701	PLTP	-0.163655575020599
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	2/145	157/9376	0.823720623764551	SLC25A6/SLC25A5	-0.279160962891665
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	3/145	233/9376	0.832558827882196	FN1/FBLN1/ACTG1	-0.324370327980731
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/145	78/9376	0.829000884173298	ISYNA1	-0.190060408811154
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/145	80/9376	0.808275862068966	RPS6	-0.215833569623087
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/145	86/9376	0.751884522854852	GNAS	-0.289694659001874
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/145	86/9376	0.751884522854852	ACTG1	-0.289694659001874
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/145	250/9376	0.775944827586207	FOLR3/DAB2/VPS28	-0.450018129516612
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/145	89/9376	0.726540100736149	GNAS	-0.324859965508325
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/145	90/9376	0.718467432950192	GNAS	-0.336341780730435
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	3/145	254/9376	0.763725224002172	SLC25A6/GNAS/SLC25A5	-0.47844767478953
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/145	91/9376	0.710572186434255	GNAS	-0.347708469816453
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/145	93/9376	0.695291064145347	ACTG1	-0.370107387051652
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/145	93/9376	0.695291064145347	HLA-DRA	-0.370107387051652
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/145	93/9376	0.695291064145347	FN1	-0.370107387051652
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	2/145	180/9376	0.718467432950192	CD74/HLA-DRA	-0.477981046075929
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/145	97/9376	0.666619267685745	GNAS	-0.413638581234031
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/145	98/9376	0.65981703026038	GNAS	-0.424271330279402
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/145	99/9376	0.653152211772902	GNAS	-0.434808486812402
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/145	99/9376	0.653152211772902	GNAS	-0.434808486812402
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/145	99/9376	0.653152211772902	ACTG1	-0.434808486812402
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/145	101/9376	0.640218504609082	GNAS	-0.455604299824515
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/145	102/9376	0.63394185260311	GNAS	-0.465866928530743
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/145	196/9376	0.65981703026038	RPS27A/UBA52	-0.603204436493914
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/145	108/9376	0.598722860791826	EEF1A1	-0.525664377886612
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/145	109/9376	0.593229990509333	SPP1	-0.535350061471872
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/145	110/9376	0.587836990595611	HSP90AB1	-0.544959804937824
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/145	112/9376	0.577339901477832	HLA-DRA	-0.563957338009499
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/145	115/9376	0.562278860569715	GNAS	-0.591919657434483
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/145	115/9376	0.562278860569715	GNAS	-0.591919657434483
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/145	116/9376	0.55743162901308	TKT	-0.601103335837636
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/145	116/9376	0.55743162901308	GNAS	-0.601103335837636
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/145	117/9376	0.552667256115532	ACTG1	-0.610220567561417
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/145	120/9376	0.538850574712644	BEX3	-0.637185501936885
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/145	122/9376	0.530016958733748	EEF2	-0.654851186676468
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/145	122/9376	0.530016958733748	ACTG1	-0.654851186676468
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/145	226/9376	0.572230698809887	CGA/GNAS	-0.815827894801579
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/145	130/9376	0.497400530503979	GNAS	-0.723206001210771
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/145	133/9376	0.486180969665543	GNAS	-0.747953834518545
NA	NA	hsa04519	Cadherin signaling	4/145	404/9376	0.640218504609082	KRT18/KRT7/KRT8/ACTG1	-0.926467387773254
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/145	136/9376	0.475456389452333	RACK1	-0.772254297323106
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/145	138/9376	0.468565717141429	RPS6	-0.788216270527775
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/145	142/9376	0.455366682855755	CYBA	-0.819593878578689
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/145	333/9376	0.582541161851507	FN1/SPP1/GNAS	-0.972130961486155
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/145	144/9376	0.44904214559387	DUSP9	-0.835020217385085
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/145	250/9376	0.517296551724138	CTSL/VAMP8	-0.969517019241772
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/145	149/9376	0.433973617218237	GNAS	-0.872860442711256
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/145	154/9376	0.419883564711151	GNAS	-0.909721031161463
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/145	155/9376	0.417174638487208	GNAS	-0.916981436080508
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/145	157/9376	0.411860311882275	ACTG1	-0.931394500911164
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/145	158/9376	0.409253601047577	CDKN1C	-0.938548107624246
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/145	158/9376	0.409253601047577	RPS6	-0.938548107624246
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	1/145	160/9376	0.404137931034483	HLA-DRA	-0.952751765829627
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/145	168/9376	0.384893267651888	CSH1	-1.00824883714969
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/145	170/9376	0.380365111561866	ACTG1	-1.02180989008479
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/145	174/9376	0.37162108600872	HSP90AB1	-1.04857711926262
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/145	300/9376	0.431080459770115	DUSP9/HSPB1	-1.2551900791269
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/145	191/9376	0.338544863693808	GNAS	-1.15750469248352
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/145	194/9376	0.333309633842872	ACTG1	-1.17598468009004
NA	NA	hsa04082	Neuroactive ligand signaling	1/145	199/9376	0.324935019927222	GNAS	-1.2063324632118
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/145	205/9376	0.31542472666106	HLA-DRA	-1.242038494484
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/145	227/9376	0.284854929363512	GNAS	-1.36699059974744
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/145	243/9376	0.266099049240812	HNRNPA1	-1.4527106557665
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	2/145	370/9376	0.349524697110904	CSH1/CGA	-1.59996678382717
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/145	298/9376	0.216986808609118	CSH1	-1.72158070011645
NA	NA	hsa04517	IgSF CAM signaling	1/145	299/9376	0.216261100219121	ACTG1	-1.72616017731677
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/145	323/9376	0.20019216397993	TIMP3	-1.83331005160506
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/145	449/9376	0.144013516626987	RGS2	-2.32960652400404