ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 70/176 175/18639 0.4 42.3613636363636 1.10764509033588e-99 4.46380971405361e-97 GO:0019843 rRNA binding 17/176 65/18639 0.261538461538462 27.6978146853147 2.16556083892702e-20 4.36360509043795e-18 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 13/176 68/18639 0.191176470588235 20.246239973262 6.0583646537034e-14 8.13840318480824e-12 GO:0009055 electron transfer activity 15/176 116/18639 0.129310344827586 13.6944063479624 2.78483508500628e-13 2.80572134814383e-11 GO:0015078 proton transmembrane transporter activity 17/176 185/18639 0.0918918918918919 9.73166461916462 2.00815570488142e-12 1.61857349813443e-10 GO:0048027 mRNA 5'-UTR binding 8/176 24/18639 0.333333333333333 35.3011363636364 3.48293539130953e-11 2.33937160449623e-09 GO:0022853 active monoatomic ion transmembrane transporter activity 13/176 118/18639 0.110169491525424 11.6673247303544 8.93295668465678e-11 5.14283077702383e-09 GO:1990948 ubiquitin ligase inhibitor activity 6/176 11/18639 0.545454545454545 57.7654958677686 2.89122812900383e-10 1.45645616998568e-08 GO:0045296 cadherin binding 19/176 334/18639 0.0568862275449102 6.02444542732716 4.23991517508318e-10 1.89853979506502e-08 GO:0055105 ubiquitin-protein transferase inhibitor activity 6/176 15/18639 0.4 42.3613636363636 3.03540366123371e-09 1.22326767547718e-07 GO:0008137 NADH dehydrogenase (ubiquinone) activity 8/176 41/18639 0.195121951219512 20.6640798226164 3.94698226360667e-09 1.44603077475772e-07 GO:0015399 primary active transmembrane transporter activity 13/176 166/18639 0.0783132530120482 8.29364047097481 6.25364318915844e-09 2.10018183769238e-07 GO:0003954 NADH dehydrogenase activity 8/176 44/18639 0.181818181818182 19.2551652892562 7.14695137149375e-09 2.21555492516306e-07 GO:0016651 oxidoreductase activity, acting on NAD(P)H 10/176 88/18639 0.113636363636364 12.0344783057851 1.04250956971994e-08 3.00093826140811e-07 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 8/176 58/18639 0.137931034482759 14.6073667711599 6.90780059963408e-08 1.85589576110169e-06 GO:0016209 antioxidant activity 9/176 86/18639 0.104651162790698 11.0829149048626 1.19803134890817e-07 3.01754146006245e-06 GO:0055106 ubiquitin-protein transferase regulator activity 6/176 36/18639 0.166666666666667 17.6505681818182 1.00211304602111e-06 2.36180546059097e-05 GO:0004601 peroxidase activity 7/176 57/18639 0.12280701754386 13.0056818181818 1.05490070200093e-06 2.36180546059097e-05 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/176 59/18639 0.11864406779661 12.564811248074 1.33975859474917e-06 2.84169849307324e-05 GO:0004857 enzyme inhibitor activity 16/176 416/18639 0.0384615384615385 4.07320804195804 2.19497043288164e-06 4.42286542225651e-05 GO:0022804 active transmembrane transporter activity 16/176 457/18639 0.0350109409190372 3.70777799880645 7.25412976971795e-06 0.000139210204628397 GO:0004129 cytochrome-c oxidase activity 4/176 15/18639 0.266666666666667 28.2409090909091 9.6687368424928e-06 0.000177113679432936 GO:0016675 oxidoreductase activity, acting on a heme group of donors 4/176 16/18639 0.25 26.4758522727273 1.27967385238546e-05 0.000224221114135365 GO:0003746 translation elongation factor activity 3/176 18/18639 0.166666666666667 17.6505681818182 0.000608436038230177 0.0102166551419484 GO:0051082 unfolded protein binding 6/176 121/18639 0.0495867768595041 5.25140871525169 0.00102084603715692 0.0164560381189696 GO:0004602 glutathione peroxidase activity 3/176 23/18639 0.130434782608696 13.8134881422925 0.00127550906907316 0.019770390570634 GO:0061134 peptidase regulator activity 8/176 226/18639 0.0353982300884956 3.74879324215607 0.00140497063144789 0.0209704875730925 GO:0019207 kinase regulator activity 9/176 287/18639 0.0313588850174216 3.32101282863478 0.00166223850168531 0.0239243612921136 GO:0023026 MHC class II protein complex binding 3/176 27/18639 0.111111111111111 11.7670454545455 0.00204911884885427 0.0276070424860856 GO:0016504 peptidase activator activity 4/176 57/18639 0.0701754385964912 7.43181818181818 0.00205511482526692 0.0276070424860856 GO:0003785 actin monomer binding 3/176 29/18639 0.103448275862069 10.9555250783699 0.00252467836253227 0.0317951681281407 GO:0043236 laminin binding 3/176 29/18639 0.103448275862069 10.9555250783699 0.00252467836253227 0.0317951681281407 GO:0050840 extracellular matrix binding 4/176 67/18639 0.0597014925373134 6.32259158751696 0.00370735938194568 0.0449916164393652 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/176 10/18639 0.2 21.1806818181818 0.00379581875667101 0.0449916164393652 GO:0010854 adenylate cyclase regulator activity 2/176 11/18639 0.181818181818182 19.2551652892562 0.00461063048701055 0.0516134468407014 GO:0015217 ADP transmembrane transporter activity 2/176 11/18639 0.181818181818182 19.2551652892562 0.00461063048701055 0.0516134468407014 GO:0023023 MHC protein complex binding 3/176 37/18639 0.0810810810810811 8.5867628992629 0.00508039999904511 0.0538789789372416 GO:0043394 proteoglycan binding 3/176 37/18639 0.0810810810810811 8.5867628992629 0.00508039999904511 0.0538789789372416 GO:0097371 MDM2/MDM4 family protein binding 2/176 12/18639 0.166666666666667 17.6505681818182 0.00549855131795613 0.0558836389882906 GO:0044183 protein folding chaperone 4/176 75/18639 0.0533333333333333 5.64818181818182 0.00554676317501643 0.0558836389882906 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/176 40/18639 0.075 7.94275568181818 0.00632806933155636 0.0622002912345661 GO:0005347 ATP transmembrane transporter activity 2/176 14/18639 0.142857142857143 15.1290584415584 0.00748799116009443 0.0701781497097222 GO:0061783 peptidoglycan muralytic activity 2/176 14/18639 0.142857142857143 15.1290584415584 0.00748799116009443 0.0701781497097222 GO:0031625 ubiquitin protein ligase binding 8/176 302/18639 0.0264900662251656 2.80538832028898 0.00809410118367544 0.0736263529697423 GO:0004860 protein kinase inhibitor activity 4/176 84/18639 0.0476190476190476 5.04301948051948 0.00824905538178374 0.0736263529697423 GO:0031386 protein tag activity 2/176 15/18639 0.133333333333333 14.1204545454545 0.00858669625205431 0.0736263529697423 GO:0141047 molecular tag activity 2/176 15/18639 0.133333333333333 14.1204545454545 0.00858669625205431 0.0736263529697423 GO:0033218 amide binding 7/176 247/18639 0.0283400809716599 3.00131118881119 0.0091617632455054 0.0769206372487224 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/176 16/18639 0.125 13.2379261363636 0.00975288210364329 0.0802124793422091 GO:0019210 kinase inhibitor activity 4/176 90/18639 0.0444444444444444 4.70681818181818 0.0104600091227776 0.0819820755981447 GO:0019887 protein kinase regulator activity 7/176 255/18639 0.0274509803921569 2.90715240641711 0.0107920180137803 0.0819820755981447 GO:0008429 phosphatidylethanolamine binding 2/176 17/18639 0.117647058823529 12.4592245989305 0.0109851912712154 0.0819820755981447 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/176 17/18639 0.117647058823529 12.4592245989305 0.0109851912712154 0.0819820755981447 GO:0016018 cyclosporin A binding 2/176 17/18639 0.117647058823529 12.4592245989305 0.0109851912712154 0.0819820755981447 GO:0044389 ubiquitin-like protein ligase binding 8/176 322/18639 0.0248447204968944 2.6311405985319 0.0116226441385417 0.0851622834151326 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/176 18/18639 0.111111111111111 11.7670454545455 0.0122822856753386 0.0868379145116043 GO:0098641 cadherin binding involved in cell-cell adhesion 2/176 18/18639 0.111111111111111 11.7670454545455 0.0122822856753386 0.0868379145116043 GO:0005080 protein kinase C binding 3/176 52/18639 0.0576923076923077 6.10981206293706 0.0130371097890984 0.0905854352587356 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/176 19/18639 0.105263157894737 11.1477272727273 0.0136428463595486 0.0931875776762389 GO:0010851 cyclase regulator activity 2/176 20/18639 0.1 10.5903409090909 0.0150655732518921 0.0995315741067623 GO:0016505 peptidase activator activity involved in apoptotic process 2/176 20/18639 0.1 10.5903409090909 0.0150655732518921 0.0995315741067623 GO:1901681 sulfur compound binding 7/176 275/18639 0.0254545454545455 2.69572314049587 0.0157774985149873 0.102553740347418 GO:0000295 adenine nucleotide transmembrane transporter activity 2/176 23/18639 0.0869565217391304 9.20899209486166 0.0196940287952172 0.124010837569883 GO:0017134 fibroblast growth factor binding 2/176 23/18639 0.0869565217391304 9.20899209486166 0.0196940287952172 0.124010837569883 GO:0043022 ribosome binding 4/176 112/18639 0.0357142857142857 3.78226461038961 0.0216998480923522 0.134539058172584 GO:0120020 cholesterol transfer activity 2/176 25/18639 0.08 8.47227272727273 0.0230674907628507 0.140851496627709 GO:0015216 purine nucleotide transmembrane transporter activity 2/176 26/18639 0.0769230769230769 8.14641608391609 0.0248369415685496 0.147195403707728 GO:0050750 low-density lipoprotein particle receptor binding 2/176 26/18639 0.0769230769230769 8.14641608391609 0.0248369415685496 0.147195403707728 GO:0043021 ribonucleoprotein complex binding 5/176 177/18639 0.0282485875706215 2.99162172573189 0.0264861672764007 0.14922176189734 GO:0004364 glutathione transferase activity 2/176 27/18639 0.0740740740740741 7.84469696969697 0.0266599673861253 0.14922176189734 GO:0015252 proton channel activity 2/176 27/18639 0.0740740740740741 7.84469696969697 0.0266599673861253 0.14922176189734 GO:0035255 ionotropic glutamate receptor binding 2/176 27/18639 0.0740740740740741 7.84469696969697 0.0266599673861253 0.14922176189734 GO:0005539 glycosaminoglycan binding 6/176 242/18639 0.0247933884297521 2.62570435762585 0.0275820290765502 0.152267913943147 GO:0005518 collagen binding 3/176 72/18639 0.0416666666666667 4.41264204545455 0.0307071247761553 0.16722934168636 GO:0001968 fibronectin binding 2/176 30/18639 0.0666666666666667 7.06022727272727 0.0324390064354539 0.172012099914315 GO:0015215 nucleotide transmembrane transporter activity 2/176 30/18639 0.0666666666666667 7.06022727272727 0.0324390064354539 0.172012099914315 GO:0070325 lipoprotein particle receptor binding 2/176 31/18639 0.0645161290322581 6.8324780058651 0.0344649272740872 0.180381372616327 GO:0098631 cell adhesion mediator activity 3/176 76/18639 0.0394736842105263 4.18039772727273 0.0352297022204126 0.181791823952616 GO:0071813 lipoprotein particle binding 2/176 32/18639 0.0625 6.61896306818182 0.0365388033254637 0.181791823952616 GO:0071814 protein-lipid complex binding 2/176 32/18639 0.0625 6.61896306818182 0.0365388033254637 0.181791823952616 GO:0120015 sterol transfer activity 2/176 32/18639 0.0625 6.61896306818182 0.0365388033254637 0.181791823952616 GO:0048306 calcium-dependent protein binding 3/176 80/18639 0.0375 3.97137784090909 0.0400765007566584 0.196961339084553 GO:0051427 hormone receptor binding 2/176 34/18639 0.0588235294117647 6.22961229946524 0.0408261366540622 0.19822810929623 GO:0001540 amyloid-beta binding 3/176 83/18639 0.036144578313253 3.82783406352683 0.043921528084085 0.205032201144591 GO:0008135 translation factor activity, RNA binding 3/176 83/18639 0.036144578313253 3.82783406352683 0.043921528084085 0.205032201144591 GO:0180051 translation factor activity 3/176 84/18639 0.0357142857142857 3.78226461038961 0.0452427307767628 0.205032201144591 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/176 36/18639 0.0555555555555556 5.88352272727273 0.0452925946208225 0.205032201144591 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/176 36/18639 0.0555555555555556 5.88352272727273 0.0452925946208225 0.205032201144591 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/176 36/18639 0.0555555555555556 5.88352272727273 0.0452925946208225 0.205032201144591 GO:0020037 heme binding 4/176 142/18639 0.028169014084507 2.98319462227913 0.045788829039735 0.205032201144591 GO:0042162 telomeric DNA binding 2/176 38/18639 0.0526315789473684 5.57386363636364 0.0499300122332731 0.221118625604495 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/176 39/18639 0.0512820512820513 5.43094405594406 0.0523103452994325 0.229142056039905 GO:0050997 quaternary ammonium group binding 2/176 40/18639 0.05 5.29517045454546 0.0547304650872154 0.237165348711267 GO:0046906 tetrapyrrole binding 4/176 152/18639 0.0263157894736842 2.78693181818182 0.0561608057423367 0.240774518235763 GO:0016859 cis-trans isomerase activity 2/176 42/18639 0.0476190476190476 5.04301948051948 0.0596862632915592 0.250557959442691 GO:0035198 miRNA binding 2/176 42/18639 0.0476190476190476 5.04301948051948 0.0596862632915592 0.250557959442691 GO:0004867 serine-type endopeptidase inhibitor activity 3/176 95/18639 0.0315789473684211 3.34431818181818 0.0610462919931961 0.253279705229284 GO:0008200 ion channel inhibitor activity 2/176 43/18639 0.0465116279069767 4.9257399577167 0.0622200764707174 0.253279705229284 GO:0048156 tau protein binding 2/176 43/18639 0.0465116279069767 4.9257399577167 0.0622200764707174 0.253279705229284 GO:0016248 channel inhibitor activity 2/176 44/18639 0.0454545454545455 4.81379132231405 0.0647899455344912 0.261103480504 GO:0004866 endopeptidase inhibitor activity 4/176 161/18639 0.0248447204968944 2.6311405985319 0.0664869497007341 0.26268863460192 GO:0005178 integrin binding 4/176 161/18639 0.0248447204968944 2.6311405985319 0.0664869497007341 0.26268863460192 GO:0141110 transporter inhibitor activity 2/176 45/18639 0.0444444444444444 4.70681818181818 0.0673949725835807 0.263691009234787 GO:0030291 protein serine/threonine kinase inhibitor activity 2/176 46/18639 0.0434782608695652 4.60449604743083 0.0700342732878527 0.271382808990429 GO:0005504 fatty acid binding 2/176 47/18639 0.0425531914893617 4.50652804642166 0.0727069767125721 0.279056301096824 GO:0005201 extracellular matrix structural constituent 4/176 168/18639 0.0238095238095238 2.52150974025974 0.075154197547407 0.285727751052877 GO:0030414 peptidase inhibitor activity 4/176 169/18639 0.0236686390532544 2.50658956428187 0.0764369623174237 0.287284076075849 GO:0035254 glutamate receptor binding 2/176 49/18639 0.0408163265306122 4.32258812615955 0.0781491739330609 0.287284076075849 GO:0008201 heparin binding 4/176 172/18639 0.0232558139534884 2.46286997885835 0.0803512027818385 0.287284076075849 GO:0015605 organophosphate ester transmembrane transporter activity 2/176 50/18639 0.04 4.23613636363636 0.0809169913008818 0.287284076075849 GO:0030544 Hsp70 protein binding 2/176 51/18639 0.0392156862745098 4.15307486631016 0.0837148581998062 0.287284076075849 GO:0042393 histone binding 5/176 247/18639 0.0202429149797571 2.14379370629371 0.0852888365211868 0.287284076075849 GO:0042277 peptide binding 5/176 249/18639 0.0200803212851406 2.12657447973713 0.0875481414325138 0.287284076075849 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/176 53/18639 0.0377358490566038 3.99635506003431 0.0893975270114463 0.287284076075849 GO:0001094 TFIID-class transcription factor complex binding 1/176 10/18639 0.1 10.5903409090909 0.0905336914680717 0.287284076075849 GO:0003796 lysozyme activity 1/176 10/18639 0.1 10.5903409090909 0.0905336914680717 0.287284076075849 GO:0005131 growth hormone receptor binding 1/176 10/18639 0.1 10.5903409090909 0.0905336914680717 0.287284076075849 GO:0005345 purine nucleobase transmembrane transporter activity 1/176 10/18639 0.1 10.5903409090909 0.0905336914680717 0.287284076075849 GO:0005522 profilin binding 1/176 10/18639 0.1 10.5903409090909 0.0905336914680717 0.287284076075849 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/176 10/18639 0.1 10.5903409090909 0.0905336914680717 0.287284076075849 GO:0030957 Tat protein binding 1/176 10/18639 0.1 10.5903409090909 0.0905336914680717 0.287284076075849 GO:0031720 haptoglobin binding 1/176 10/18639 0.1 10.5903409090909 0.0905336914680717 0.287284076075849 GO:0032356 oxidized DNA binding 1/176 10/18639 0.1 10.5903409090909 0.0905336914680717 0.287284076075849 GO:0032395 MHC class II receptor activity 1/176 10/18639 0.1 10.5903409090909 0.0905336914680717 0.287284076075849 GO:0070513 death domain binding 1/176 10/18639 0.1 10.5903409090909 0.0905336914680717 0.287284076075849 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/176 10/18639 0.1 10.5903409090909 0.0905336914680717 0.287284076075849 GO:0098505 G-rich strand telomeric DNA binding 1/176 10/18639 0.1 10.5903409090909 0.0905336914680717 0.287284076075849 GO:0098632 cell-cell adhesion mediator activity 2/176 55/18639 0.0363636363636364 3.85103305785124 0.0951908761999573 0.291589613278611 GO:0140313 molecular sequestering activity 2/176 55/18639 0.0363636363636364 3.85103305785124 0.0951908761999573 0.291589613278611 GO:0061135 endopeptidase regulator activity 4/176 184/18639 0.0217391304347826 2.30224802371541 0.096974035686441 0.291589613278611 GO:0008432 JUN kinase binding 1/176 11/18639 0.0909090909090909 9.6275826446281 0.099125997566178 0.291589613278611 GO:0008526 phosphatidylinositol transfer activity 1/176 11/18639 0.0909090909090909 9.6275826446281 0.099125997566178 0.291589613278611 GO:0015205 nucleobase transmembrane transporter activity 1/176 11/18639 0.0909090909090909 9.6275826446281 0.099125997566178 0.291589613278611 GO:0042608 T cell receptor binding 1/176 11/18639 0.0909090909090909 9.6275826446281 0.099125997566178 0.291589613278611 GO:0050786 RAGE receptor binding 1/176 11/18639 0.0909090909090909 9.6275826446281 0.099125997566178 0.291589613278611 GO:0050998 nitric-oxide synthase binding 1/176 11/18639 0.0909090909090909 9.6275826446281 0.099125997566178 0.291589613278611 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/176 11/18639 0.0909090909090909 9.6275826446281 0.099125997566178 0.291589613278611 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/176 57/18639 0.0350877192982456 3.71590909090909 0.101088794842312 0.293882748212597 GO:0031406 carboxylic acid binding 4/176 187/18639 0.0213903743315508 2.26531356344191 0.101364024817744 0.293882748212597 GO:0061980 regulatory RNA binding 2/176 58/18639 0.0344827586206897 3.65184169278997 0.104075109660451 0.297109220453861 GO:0043177 organic acid binding 4/176 189/18639 0.0211640211640212 2.24134199134199 0.10434110985435 0.297109220453861 GO:0004859 phospholipase inhibitor activity 1/176 12/18639 0.0833333333333333 8.82528409090909 0.107637583588744 0.297109220453861 GO:0005165 neurotrophin receptor binding 1/176 12/18639 0.0833333333333333 8.82528409090909 0.107637583588744 0.297109220453861 GO:0005527 macrolide binding 1/176 12/18639 0.0833333333333333 8.82528409090909 0.107637583588744 0.297109220453861 GO:0010853 cyclase activator activity 1/176 12/18639 0.0833333333333333 8.82528409090909 0.107637583588744 0.297109220453861 GO:0043047 single-stranded telomeric DNA binding 1/176 12/18639 0.0833333333333333 8.82528409090909 0.107637583588744 0.297109220453861 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/176 61/18639 0.0327868852459016 3.47224292101341 0.113174833325117 0.305724764944397 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/176 13/18639 0.0769230769230769 8.14641608391609 0.116069203564498 0.305724764944397 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/176 13/18639 0.0769230769230769 8.14641608391609 0.116069203564498 0.305724764944397 GO:0005542 folic acid binding 1/176 13/18639 0.0769230769230769 8.14641608391609 0.116069203564498 0.305724764944397 GO:0008035 high-density lipoprotein particle binding 1/176 13/18639 0.0769230769230769 8.14641608391609 0.116069203564498 0.305724764944397 GO:0035325 Toll-like receptor binding 1/176 13/18639 0.0769230769230769 8.14641608391609 0.116069203564498 0.305724764944397 GO:0043560 insulin receptor substrate binding 1/176 13/18639 0.0769230769230769 8.14641608391609 0.116069203564498 0.305724764944397 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/176 128/18639 0.0234375 2.48211115056818 0.120967645201598 0.311440413795213 GO:0005344 oxygen carrier activity 1/176 14/18639 0.0714285714285714 7.56452922077922 0.124421604518683 0.311440413795213 GO:0008191 metalloendopeptidase inhibitor activity 1/176 14/18639 0.0714285714285714 7.56452922077922 0.124421604518683 0.311440413795213 GO:0019992 diacylglycerol binding 1/176 14/18639 0.0714285714285714 7.56452922077922 0.124421604518683 0.311440413795213 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/176 14/18639 0.0714285714285714 7.56452922077922 0.124421604518683 0.311440413795213 GO:0032036 myosin heavy chain binding 1/176 14/18639 0.0714285714285714 7.56452922077922 0.124421604518683 0.311440413795213 GO:0044548 S100 protein binding 1/176 14/18639 0.0714285714285714 7.56452922077922 0.124421604518683 0.311440413795213 GO:0098847 sequence-specific single stranded DNA binding 1/176 14/18639 0.0714285714285714 7.56452922077922 0.124421604518683 0.311440413795213 GO:0120013 lipid transfer activity 2/176 65/18639 0.0307692307692308 3.25856643356643 0.125610434059095 0.312475339048242 GO:0031072 heat shock protein binding 3/176 131/18639 0.0229007633587786 2.42526891047883 0.127213917680297 0.312965896502955 GO:0005179 hormone activity 3/176 132/18639 0.0227272727272727 2.40689566115702 0.129321428425999 0.312965896502955 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/176 67/18639 0.0298507462686567 3.16129579375848 0.131945958350456 0.312965896502955 GO:0000774 adenyl-nucleotide exchange factor activity 1/176 15/18639 0.0666666666666667 7.06022727272727 0.132695526537728 0.312965896502955 GO:0005523 tropomyosin binding 1/176 15/18639 0.0666666666666667 7.06022727272727 0.132695526537728 0.312965896502955 GO:0016846 carbon-sulfur lyase activity 1/176 15/18639 0.0666666666666667 7.06022727272727 0.132695526537728 0.312965896502955 GO:0017081 chloride channel regulator activity 1/176 15/18639 0.0666666666666667 7.06022727272727 0.132695526537728 0.312965896502955 GO:0050780 dopamine receptor binding 1/176 15/18639 0.0666666666666667 7.06022727272727 0.132695526537728 0.312965896502955 GO:0005516 calmodulin binding 4/176 207/18639 0.0193236714975845 2.04644268774704 0.132861063766779 0.312965896502955 GO:0051087 protein-folding chaperone binding 3/176 134/18639 0.0223880597014925 2.37097184531886 0.133573533991336 0.312965896502955 GO:0005159 insulin-like growth factor receptor binding 1/176 16/18639 0.0625 6.61896306818182 0.140891702833334 0.324190905415593 GO:0043023 ribosomal large subunit binding 1/176 16/18639 0.0625 6.61896306818182 0.140891702833334 0.324190905415593 GO:0055102 lipase inhibitor activity 1/176 16/18639 0.0625 6.61896306818182 0.140891702833334 0.324190905415593 GO:0097110 scaffold protein binding 2/176 70/18639 0.0285714285714286 3.02581168831169 0.141582132389937 0.324190905415593 GO:0030169 low-density lipoprotein particle binding 1/176 17/18639 0.0588235294117647 6.22961229946524 0.149010859805966 0.33177556078345 GO:0036041 long-chain fatty acid binding 1/176 17/18639 0.0588235294117647 6.22961229946524 0.149010859805966 0.33177556078345 GO:0048038 quinone binding 1/176 17/18639 0.0588235294117647 6.22961229946524 0.149010859805966 0.33177556078345 GO:0070492 oligosaccharide binding 1/176 17/18639 0.0588235294117647 6.22961229946524 0.149010859805966 0.33177556078345 GO:1990226 histone methyltransferase binding 1/176 17/18639 0.0588235294117647 6.22961229946524 0.149010859805966 0.33177556078345 GO:0008525 phosphatidylcholine transporter activity 1/176 18/18639 0.0555555555555556 5.88352272727273 0.157053717107768 0.338463358258986 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/176 18/18639 0.0555555555555556 5.88352272727273 0.157053717107768 0.338463358258986 GO:0031690 adrenergic receptor binding 1/176 18/18639 0.0555555555555556 5.88352272727273 0.157053717107768 0.338463358258986 GO:0035615 clathrin adaptor activity 1/176 18/18639 0.0555555555555556 5.88352272727273 0.157053717107768 0.338463358258986 GO:0070064 proline-rich region binding 1/176 18/18639 0.0555555555555556 5.88352272727273 0.157053717107768 0.338463358258986 GO:1901611 phosphatidylglycerol binding 1/176 18/18639 0.0555555555555556 5.88352272727273 0.157053717107768 0.338463358258986 GO:0017022 myosin binding 2/176 76/18639 0.0263157894736842 2.78693181818182 0.161273792953467 0.341043374590109 GO:0051540 metal cluster binding 2/176 77/18639 0.025974025974026 2.75073789846517 0.164603462776219 0.341043374590109 GO:0019209 kinase activator activity 3/176 148/18639 0.0202702702702703 2.14669072481573 0.164611890065839 0.341043374590109 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/176 19/18639 0.0526315789473684 5.57386363636364 0.165020987704891 0.341043374590109 GO:0042834 peptidoglycan binding 1/176 19/18639 0.0526315789473684 5.57386363636364 0.165020987704891 0.341043374590109 GO:0043395 heparan sulfate proteoglycan binding 1/176 19/18639 0.0526315789473684 5.57386363636364 0.165020987704891 0.341043374590109 GO:0046624 sphingolipid transporter activity 1/176 19/18639 0.0526315789473684 5.57386363636364 0.165020987704891 0.341043374590109 GO:0097001 ceramide binding 1/176 19/18639 0.0526315789473684 5.57386363636364 0.165020987704891 0.341043374590109 GO:0033293 monocarboxylic acid binding 2/176 79/18639 0.0253164556962025 2.68109896432681 0.171298845016627 0.352211400722963 GO:0043024 ribosomal small subunit binding 1/176 20/18639 0.05 5.29517045454546 0.17291337793926 0.353726351824983 GO:0000049 tRNA binding 2/176 80/18639 0.025 2.64758522727273 0.174663520510473 0.355502013968285 GO:0005123 death receptor binding 1/176 21/18639 0.0476190476190476 5.04301948051948 0.180731587589761 0.357033479405263 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/176 21/18639 0.0476190476190476 5.04301948051948 0.180731587589761 0.357033479405263 GO:0051428 peptide hormone receptor binding 1/176 21/18639 0.0476190476190476 5.04301948051948 0.180731587589761 0.357033479405263 GO:0070182 DNA polymerase binding 1/176 21/18639 0.0476190476190476 5.04301948051948 0.180731587589761 0.357033479405263 GO:0072542 protein phosphatase activator activity 1/176 21/18639 0.0476190476190476 5.04301948051948 0.180731587589761 0.357033479405263 GO:0140312 cargo adaptor activity 1/176 21/18639 0.0476190476190476 5.04301948051948 0.180731587589761 0.357033479405263 GO:0031683 G-protein beta/gamma-subunit complex binding 1/176 22/18639 0.0454545454545455 4.81379132231405 0.188476309932881 0.36871821797549 GO:0140517 protein-RNA adaptor activity 1/176 22/18639 0.0454545454545455 4.81379132231405 0.188476309932881 0.36871821797549 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/176 86/18639 0.0232558139534884 2.46286997885835 0.195058030011221 0.379750657461459 GO:0099186 structural constituent of postsynapse 1/176 23/18639 0.0434782608695652 4.60449604743083 0.196148231802775 0.380037199117876 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/176 24/18639 0.0416666666666667 4.41264204545455 0.203748033650793 0.387313479062593 GO:0005315 phosphate transmembrane transporter activity 1/176 24/18639 0.0416666666666667 4.41264204545455 0.203748033650793 0.387313479062593 GO:0015295 solute:proton symporter activity 1/176 24/18639 0.0416666666666667 4.41264204545455 0.203748033650793 0.387313479062593 GO:0070300 phosphatidic acid binding 1/176 24/18639 0.0416666666666667 4.41264204545455 0.203748033650793 0.387313479062593 GO:0019211 phosphatase activator activity 1/176 25/18639 0.04 4.23613636363636 0.211276389604457 0.399738896763363 GO:0072341 modified amino acid binding 2/176 91/18639 0.021978021978022 2.32754745254745 0.212272263147158 0.399746364711705 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/176 26/18639 0.0384615384615385 4.07320804195804 0.218733967525893 0.402510451657238 GO:0019865 immunoglobulin binding 1/176 26/18639 0.0384615384615385 4.07320804195804 0.218733967525893 0.402510451657238 GO:0030247 polysaccharide binding 1/176 26/18639 0.0384615384615385 4.07320804195804 0.218733967525893 0.402510451657238 GO:0043548 phosphatidylinositol 3-kinase binding 1/176 26/18639 0.0384615384615385 4.07320804195804 0.218733967525893 0.402510451657238 GO:0120014 phospholipid transfer activity 1/176 26/18639 0.0384615384615385 4.07320804195804 0.218733967525893 0.402510451657238 GO:0003713 transcription coactivator activity 4/176 256/18639 0.015625 1.65474076704545 0.223447841217042 0.4093158182294 GO:0046625 sphingolipid binding 1/176 28/18639 0.0357142857142857 3.78226461038961 0.233439429740466 0.423766172006341 GO:0097718 disordered domain specific binding 1/176 28/18639 0.0357142857142857 3.78226461038961 0.233439429740466 0.423766172006341 GO:0003730 mRNA 3'-UTR binding 4/176 262/18639 0.0152671755725191 1.61684594031922 0.235521519911478 0.425628576342268 GO:0016853 isomerase activity 3/176 180/18639 0.0166666666666667 1.76505681818182 0.241906704533289 0.435216080030872 GO:0043130 ubiquitin binding 2/176 100/18639 0.02 2.11806818181818 0.243579241442095 0.436277485782952 GO:0001965 G-protein alpha-subunit binding 1/176 30/18639 0.0333333333333333 3.53011363636364 0.247869640070471 0.4381204603 GO:0031210 phosphatidylcholine binding 1/176 30/18639 0.0333333333333333 3.53011363636364 0.247869640070471 0.4381204603 GO:0098918 structural constituent of synapse 1/176 30/18639 0.0333333333333333 3.53011363636364 0.247869640070471 0.4381204603 GO:1901981 phosphatidylinositol phosphate binding 3/176 185/18639 0.0162162162162162 1.71735257985258 0.254523472159557 0.447916852752408 GO:0031369 translation initiation factor binding 1/176 32/18639 0.03125 3.30948153409091 0.2620297216961 0.455163697601415 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/176 32/18639 0.03125 3.30948153409091 0.2620297216961 0.455163697601415 GO:0051059 NF-kappaB binding 1/176 32/18639 0.03125 3.30948153409091 0.2620297216961 0.455163697601415 GO:0019888 protein phosphatase regulator activity 2/176 107/18639 0.0186915887850467 1.97950297366185 0.268065667900319 0.461323599248068 GO:0030296 protein tyrosine kinase activator activity 1/176 33/18639 0.0303030303030303 3.20919421487603 0.269010039263762 0.461323599248068 GO:0140311 protein sequestering activity 1/176 33/18639 0.0303030303030303 3.20919421487603 0.269010039263762 0.461323599248068 GO:0019825 oxygen binding 1/176 34/18639 0.0294117647058824 3.11480614973262 0.275924702979207 0.46918841898996 GO:0030332 cyclin binding 1/176 34/18639 0.0294117647058824 3.11480614973262 0.275924702979207 0.46918841898996 GO:1902936 phosphatidylinositol bisphosphate binding 2/176 111/18639 0.018018018018018 1.90816953316953 0.282061759701567 0.474825223850026 GO:0005154 epidermal growth factor receptor binding 1/176 35/18639 0.0285714285714286 3.02581168831169 0.282774326858576 0.474825223850026 GO:0016229 steroid dehydrogenase activity 1/176 35/18639 0.0285714285714286 3.02581168831169 0.282774326858576 0.474825223850026 GO:0005484 SNAP receptor activity 1/176 36/18639 0.0277777777777778 2.94176136363636 0.289559519208226 0.482200356367418 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/176 36/18639 0.0277777777777778 2.94176136363636 0.289559519208226 0.482200356367418 GO:0016829 lyase activity 3/176 200/18639 0.015 1.58855113636364 0.292854394753924 0.485680333686548 GO:0030280 structural constituent of skin epidermis 1/176 37/18639 0.027027027027027 2.8622542997543 0.296280882677524 0.48934916278296 GO:0019208 phosphatase regulator activity 2/176 117/18639 0.0170940170940171 1.81031468531469 0.303010044621049 0.498420604009317 GO:0032182 ubiquitin-like protein binding 2/176 120/18639 0.0166666666666667 1.76505681818182 0.313447583749131 0.51292616790561 GO:0071855 neuropeptide receptor binding 1/176 40/18639 0.025 2.64758522727273 0.316067942537184 0.51292616790561 GO:0140662 ATP-dependent protein folding chaperone 1/176 40/18639 0.025 2.64758522727273 0.316067942537184 0.51292616790561 GO:0003697 single-stranded DNA binding 2/176 121/18639 0.0165289256198347 1.75046957175056 0.316919642204707 0.51292616790561 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/176 122/18639 0.0163934426229508 1.73612146050671 0.320387738236225 0.515807865003218 GO:0042169 SH2 domain binding 1/176 41/18639 0.024390243902439 2.58300997782705 0.322539905659581 0.515807865003218 GO:0042287 MHC protein binding 1/176 41/18639 0.024390243902439 2.58300997782705 0.322539905659581 0.515807865003218 GO:0004520 DNA endonuclease activity 1/176 42/18639 0.0238095238095238 2.52150974025974 0.328950970107581 0.516404085380616 GO:0042056 chemoattractant activity 1/176 42/18639 0.0238095238095238 2.52150974025974 0.328950970107581 0.516404085380616 GO:0048487 beta-tubulin binding 1/176 42/18639 0.0238095238095238 2.52150974025974 0.328950970107581 0.516404085380616 GO:0051879 Hsp90 protein binding 1/176 42/18639 0.0238095238095238 2.52150974025974 0.328950970107581 0.516404085380616 GO:0005543 phospholipid binding 6/176 497/18639 0.0120724346076459 1.27851198097677 0.329319726905256 0.516404085380616 GO:0004519 endonuclease activity 2/176 127/18639 0.015748031496063 1.66777022190408 0.337660760732466 0.527431343314665 GO:0001046 core promoter sequence-specific DNA binding 1/176 44/18639 0.0227272727272727 2.40689566115702 0.341592676836314 0.527440033582508 GO:0001223 transcription coactivator binding 1/176 44/18639 0.0227272727272727 2.40689566115702 0.341592676836314 0.527440033582508 GO:0030547 signaling receptor inhibitor activity 1/176 44/18639 0.0227272727272727 2.40689566115702 0.341592676836314 0.527440033582508 GO:0042605 peptide antigen binding 1/176 45/18639 0.0222222222222222 2.35340909090909 0.347824442842058 0.533190100436777 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/176 130/18639 0.0153846153846154 1.62928321678322 0.347962770260229 0.533190100436777 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/176 132/18639 0.0151515151515152 1.60459710743802 0.35480159931654 0.541610017138506 GO:0001784 phosphotyrosine residue binding 1/176 47/18639 0.0212765957446809 2.25326402321083 0.360112570351659 0.547642890006486 GO:0015297 antiporter activity 2/176 135/18639 0.0148148148148148 1.56893939393939 0.365012242595703 0.54784558605561 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/176 48/18639 0.0208333333333333 2.20632102272727 0.366170024504957 0.54784558605561 GO:0038187 pattern recognition receptor activity 1/176 48/18639 0.0208333333333333 2.20632102272727 0.366170024504957 0.54784558605561 GO:0140693 molecular condensate scaffold activity 1/176 48/18639 0.0208333333333333 2.20632102272727 0.366170024504957 0.54784558605561 GO:0002020 protease binding 2/176 136/18639 0.0147058823529412 1.55740307486631 0.368402366801663 0.54784558605561 GO:0019838 growth factor binding 2/176 136/18639 0.0147058823529412 1.55740307486631 0.368402366801663 0.54784558605561 GO:0060590 ATPase regulator activity 1/176 49/18639 0.0204081632653061 2.16129406307978 0.372170458891871 0.551414319608177 GO:0005006 epidermal growth factor receptor activity 1/176 50/18639 0.02 2.11806818181818 0.378114407210055 0.554718563878406 GO:0032813 tumor necrosis factor receptor superfamily binding 1/176 50/18639 0.02 2.11806818181818 0.378114407210055 0.554718563878406 GO:0030295 protein kinase activator activity 2/176 139/18639 0.0143884892086331 1.523790058862 0.378530037386009 0.554718563878406 GO:0003924 GTPase activity 4/176 331/18639 0.0120845921450151 1.27979950563032 0.381219522698817 0.556635752346461 GO:0019903 protein phosphatase binding 2/176 144/18639 0.0138888888888889 1.47088068181818 0.395257408667997 0.567373228454576 GO:0004864 protein phosphatase inhibitor activity 1/176 53/18639 0.0188679245283019 1.99817753001715 0.395612598500585 0.567373228454576 GO:0005544 calcium-dependent phospholipid binding 1/176 53/18639 0.0188679245283019 1.99817753001715 0.395612598500585 0.567373228454576 GO:0051018 protein kinase A binding 1/176 53/18639 0.0188679245283019 1.99817753001715 0.395612598500585 0.567373228454576 GO:0140296 general transcription initiation factor binding 1/176 53/18639 0.0188679245283019 1.99817753001715 0.395612598500585 0.567373228454576 GO:0003925 G protein activity 1/176 54/18639 0.0185185185185185 1.96117424242424 0.401335840869244 0.569501210810935 GO:0050661 NADP binding 1/176 54/18639 0.0185185185185185 1.96117424242424 0.401335840869244 0.569501210810935 GO:0051287 NAD binding 1/176 54/18639 0.0185185185185185 1.96117424242424 0.401335840869244 0.569501210810935 GO:0003779 actin binding 5/176 443/18639 0.0112866817155756 1.19529807100349 0.407447384397853 0.576144897938017 GO:0019212 phosphatase inhibitor activity 1/176 56/18639 0.0178571428571429 1.89113230519481 0.412621156670582 0.581420720763093 GO:0019842 vitamin binding 2/176 150/18639 0.0133333333333333 1.41204545454545 0.415056394761066 0.582814380100034 GO:0001786 phosphatidylserine binding 1/176 59/18639 0.0169491525423729 1.79497303543914 0.429153706490927 0.591649034152239 GO:0036002 pre-mRNA binding 1/176 59/18639 0.0169491525423729 1.79497303543914 0.429153706490927 0.591649034152239 GO:0045309 protein phosphorylated amino acid binding 1/176 59/18639 0.0169491525423729 1.79497303543914 0.429153706490927 0.591649034152239 GO:0070063 RNA polymerase binding 1/176 59/18639 0.0169491525423729 1.79497303543914 0.429153706490927 0.591649034152239 GO:0045182 translation regulator activity 4/176 356/18639 0.0112359550561798 1.18992594484168 0.434341982378012 0.591649034152239 GO:0140375 immune receptor activity 2/176 156/18639 0.0128205128205128 1.35773601398601 0.434529687846441 0.591649034152239 GO:0001098 basal transcription machinery binding 1/176 60/18639 0.0166666666666667 1.76505681818182 0.434561077193704 0.591649034152239 GO:0001099 basal RNA polymerase II transcription machinery binding 1/176 60/18639 0.0166666666666667 1.76505681818182 0.434561077193704 0.591649034152239 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/176 60/18639 0.0166666666666667 1.76505681818182 0.434561077193704 0.591649034152239 GO:0019905 syntaxin binding 1/176 61/18639 0.0163934426229508 1.73612146050671 0.439917514591514 0.596925112391852 GO:0099106 ion channel regulator activity 2/176 160/18639 0.0125 1.32379261363636 0.447318611686785 0.604930874193874 GO:0005507 copper ion binding 1/176 63/18639 0.0158730158730159 1.68100649350649 0.450479493178142 0.607168012544452 GO:0008083 growth factor activity 2/176 162/18639 0.0123456790123457 1.30744949494949 0.453652632848278 0.60940670345952 GO:0004536 DNA nuclease activity 1/176 64/18639 0.015625 1.65474076704545 0.455685975154921 0.610104478363565 GO:0038024 cargo receptor activity 1/176 65/18639 0.0153846153846154 1.62928321678322 0.460843405484543 0.614966531159837 GO:0016874 ligase activity 2/176 167/18639 0.0119760479041916 1.26830430048993 0.469305566045814 0.624191891473476 GO:0016247 channel regulator activity 2/176 168/18639 0.0119047619047619 1.26075487012987 0.472404266420718 0.626246445287992 GO:0005548 phospholipid transporter activity 1/176 68/18639 0.0147058823529412 1.55740307486631 0.476025960355008 0.62897856401006 GO:0141108 transporter regulator activity 2/176 170/18639 0.0117647058823529 1.24592245989305 0.478569164299319 0.630272461479169 GO:0004521 RNA endonuclease activity 1/176 73/18639 0.0136986301369863 1.45073163138232 0.500391241409507 0.654554128539929 GO:0005319 lipid transporter activity 2/176 178/18639 0.0112359550561798 1.18992594484168 0.502785441170321 0.654554128539929 GO:0035091 phosphatidylinositol binding 3/176 284/18639 0.0105633802816901 1.11869798335467 0.50395207378382 0.654554128539929 GO:0003684 damaged DNA binding 1/176 74/18639 0.0135135135135135 1.43112714987715 0.505127379592849 0.654554128539929 GO:0035064 methylated histone binding 1/176 74/18639 0.0135135135135135 1.43112714987715 0.505127379592849 0.654554128539929 GO:0003725 double-stranded RNA binding 1/176 75/18639 0.0133333333333333 1.41204545454545 0.509818873327923 0.65526099412522 GO:0015291 secondary active transmembrane transporter activity 3/176 287/18639 0.0104529616724739 1.10700427621159 0.510984070766226 0.65526099412522 GO:0051536 iron-sulfur cluster binding 1/176 76/18639 0.0131578947368421 1.39346590909091 0.514466141066249 0.65526099412522 GO:0140034 methylation-dependent protein binding 1/176 76/18639 0.0131578947368421 1.39346590909091 0.514466141066249 0.65526099412522 GO:0019199 transmembrane receptor protein kinase activity 1/176 78/18639 0.0128205128205128 1.35773601398601 0.523629652895835 0.65526099412522 GO:0016835 carbon-oxygen lyase activity 1/176 79/18639 0.0126582278481013 1.34054948216341 0.528146714535312 0.65526099412522 GO:0046332 SMAD binding 1/176 79/18639 0.0126582278481013 1.34054948216341 0.528146714535312 0.65526099412522 GO:0008234 cysteine-type peptidase activity 2/176 187/18639 0.0106951871657754 1.13265678172095 0.529153257047607 0.65526099412522 GO:0001618 virus receptor activity 1/176 81/18639 0.0123456790123457 1.30744949494949 0.537053464637695 0.65526099412522 GO:0030971 receptor tyrosine kinase binding 1/176 81/18639 0.0123456790123457 1.30744949494949 0.537053464637695 0.65526099412522 GO:0033192 calmodulin-dependent protein phosphatase activity 1/176 81/18639 0.0123456790123457 1.30744949494949 0.537053464637695 0.65526099412522 GO:0140791 histone H2AXS140 phosphatase activity 1/176 81/18639 0.0123456790123457 1.30744949494949 0.537053464637695 0.65526099412522 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/176 81/18639 0.0123456790123457 1.30744949494949 0.537053464637695 0.65526099412522 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/176 81/18639 0.0123456790123457 1.30744949494949 0.537053464637695 0.65526099412522 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/176 81/18639 0.0123456790123457 1.30744949494949 0.537053464637695 0.65526099412522 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/176 81/18639 0.0123456790123457 1.30744949494949 0.537053464637695 0.65526099412522 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/176 81/18639 0.0123456790123457 1.30744949494949 0.537053464637695 0.65526099412522 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/176 81/18639 0.0123456790123457 1.30744949494949 0.537053464637695 0.65526099412522 GO:0019902 phosphatase binding 2/176 190/18639 0.0105263157894737 1.11477272727273 0.537730992197096 0.65526099412522 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/176 82/18639 0.0121951219512195 1.29150498891353 0.541443947999251 0.65526099412522 GO:0033549 MAP kinase phosphatase activity 1/176 82/18639 0.0121951219512195 1.29150498891353 0.541443947999251 0.65526099412522 GO:0140272 exogenous protein binding 1/176 82/18639 0.0121951219512195 1.29150498891353 0.541443947999251 0.65526099412522 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/176 83/18639 0.0120481927710843 1.27594468784228 0.545793027330616 0.658546676689336 GO:0017018 myosin phosphatase activity 1/176 84/18639 0.0119047619047619 1.26075487012987 0.550101090878245 0.661763401862486 GO:0050660 flavin adenine dinucleotide binding 1/176 86/18639 0.0116279069767442 1.23143498942918 0.558595705542347 0.669982349207041 GO:0004197 cysteine-type endopeptidase activity 1/176 88/18639 0.0113636363636364 1.20344783057851 0.56693082616773 0.676849770921706 GO:0003727 single-stranded RNA binding 1/176 89/18639 0.0112359550561798 1.18992594484168 0.571039508966204 0.676849770921706 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/176 89/18639 0.0112359550561798 1.18992594484168 0.571039508966204 0.676849770921706 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/176 89/18639 0.0112359550561798 1.18992594484168 0.571039508966204 0.676849770921706 GO:0140793 histone H2AXY142 phosphatase activity 1/176 90/18639 0.0111111111111111 1.17670454545455 0.575109430606201 0.67967478162551 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/176 91/18639 0.010989010989011 1.16377372627373 0.579140954689079 0.682438025554675 GO:0051219 phosphoprotein binding 1/176 93/18639 0.010752688172043 1.13874633431085 0.587090247663534 0.688648014100301 GO:0004518 nuclease activity 2/176 209/18639 0.00956937799043062 1.01342975206612 0.589537381798025 0.688648014100301 GO:0051015 actin filament binding 2/176 209/18639 0.00956937799043062 1.01342975206612 0.589537381798025 0.688648014100301 GO:0004896 cytokine receptor activity 1/176 96/18639 0.0104166666666667 1.10316051136364 0.598735102151787 0.697370653662342 GO:0004725 protein tyrosine phosphatase activity 1/176 98/18639 0.0102040816326531 1.08064703153989 0.606316329862267 0.70416565110805 GO:0004722 protein serine/threonine phosphatase activity 1/176 103/18639 0.00970873786407767 1.02818843777582 0.624652048921181 0.723375792285161 GO:0000149 SNARE binding 1/176 106/18639 0.00943396226415094 0.999088765008576 0.63524324459374 0.733533030290193 GO:0005496 steroid binding 1/176 108/18639 0.00925925925925926 0.980587121212121 0.642138412985102 0.739376515522846 GO:0005200 structural constituent of cytoskeleton 1/176 112/18639 0.00892857142857143 0.945566152597403 0.655542324745113 0.752659706188834 GO:0001221 transcription coregulator binding 1/176 115/18639 0.00869565217391304 0.920899209486166 0.665266566096963 0.7594969578954 GO:0017124 SH3 domain binding 1/176 115/18639 0.00869565217391304 0.920899209486166 0.665266566096963 0.7594969578954 GO:0015294 solute:monoatomic cation symporter activity 1/176 116/18639 0.00862068965517241 0.912960423197492 0.668446931264688 0.760972071467992 GO:1990782 protein tyrosine kinase binding 1/176 117/18639 0.00854700854700855 0.905157342657343 0.671597249252995 0.762404764644949 GO:0140297 DNA-binding transcription factor binding 4/176 488/18639 0.00819672131147541 0.868060730253353 0.680294895103262 0.770109108782626 GO:0004540 RNA nuclease activity 1/176 121/18639 0.00826446280991736 0.875234785875282 0.683903655414136 0.770252421260442 GO:0140104 molecular carrier activity 2/176 249/18639 0.00803212851405622 0.850629791894852 0.684244086380243 0.770252421260442 GO:0003712 transcription coregulator activity 4/176 495/18639 0.00808080808080808 0.855785123966942 0.691050362026443 0.775747342330519 GO:0005525 GTP binding 3/176 378/18639 0.00793650793650794 0.840503246753247 0.69599152033993 0.779123840824977 GO:0019783 ubiquitin-like protein peptidase activity 1/176 127/18639 0.0078740157480315 0.83388511095204 0.701508647780757 0.780961284684102 GO:0042826 histone deacetylase binding 1/176 127/18639 0.0078740157480315 0.83388511095204 0.701508647780757 0.780961284684102 GO:0035591 signaling adaptor activity 1/176 129/18639 0.00775193798449612 0.82095665961945 0.707157540581279 0.783621174551974 GO:0015631 tubulin binding 3/176 385/18639 0.00779220779220779 0.825221369539551 0.707786867337267 0.783621174551974 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/176 130/18639 0.00769230769230769 0.814641608391608 0.709941996165163 0.783853765628933 GO:0008514 organic anion transmembrane transporter activity 2/176 269/18639 0.00743494423791822 0.78738594119635 0.724518586845161 0.794750246842915 GO:0044325 transmembrane transporter binding 1/176 136/18639 0.00735294117647059 0.778701537433155 0.726104452459324 0.794750246842915 GO:0140789 histone phosphatase activity 1/176 136/18639 0.00735294117647059 0.778701537433155 0.726104452459324 0.794750246842915 GO:0019001 guanyl nucleotide binding 3/176 400/18639 0.0075 0.794275568181818 0.731884940109962 0.794750246842915 GO:0032561 guanyl ribonucleotide binding 3/176 400/18639 0.0075 0.794275568181818 0.731884940109962 0.794750246842915 GO:0070851 growth factor receptor binding 1/176 139/18639 0.00719424460431655 0.761895029431001 0.733846617941495 0.794750246842915 GO:0005126 cytokine receptor binding 2/176 275/18639 0.00727272727272727 0.770206611570248 0.735729312377156 0.794750246842915 GO:0004713 protein tyrosine kinase activity 1/176 140/18639 0.00714285714285714 0.756452922077922 0.736378671738376 0.794750246842915 GO:0008017 microtubule binding 2/176 276/18639 0.0072463768115942 0.767416007905138 0.737559782429902 0.794750246842915 GO:0030246 carbohydrate binding 2/176 280/18639 0.00714285714285714 0.756452922077922 0.744774532666069 0.799858106360288 GO:0019955 cytokine binding 1/176 144/18639 0.00694444444444444 0.735440340909091 0.746269597993718 0.799858106360288 GO:0015293 symporter activity 1/176 146/18639 0.00684931506849315 0.725365815691158 0.751075790890556 0.802874121296801 GO:0005506 iron ion binding 1/176 154/18639 0.00649350649350649 0.687684474616293 0.769412042708645 0.820299082570327 GO:0140713 histone chaperone activity 1/176 164/18639 0.00609756097560976 0.645752494456763 0.790454589570139 0.84041492762926 GO:0015103 inorganic anion transmembrane transporter activity 1/176 165/18639 0.00606060606060606 0.641838842975207 0.792450800245953 0.84041492762926 GO:0051020 GTPase binding 2/176 315/18639 0.00634920634920635 0.672402597402597 0.800958688357098 0.847208271411839 GO:0140030 modification-dependent protein binding 1/176 173/18639 0.00578034682080925 0.612158434051498 0.807754491506853 0.851549202538524 GO:0003823 antigen binding 1/176 174/18639 0.00574712643678161 0.608640282131661 0.809586789215874 0.851549202538524 GO:0004721 phosphoprotein phosphatase activity 1/176 175/18639 0.00571428571428571 0.605162337662338 0.811401721525542 0.851549202538524 GO:0140597 protein carrier chaperone 1/176 188/18639 0.00531914893617021 0.563316005802708 0.833487998797319 0.872138066252083 GO:0005261 monoatomic cation channel activity 2/176 341/18639 0.00586510263929619 0.621134364169555 0.83534812301068 0.872138066252083 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 2/176 349/18639 0.00573065902578797 0.606896327168533 0.844802656910567 0.879729898539944 GO:0046982 protein heterodimerization activity 2/176 369/18639 0.00542005420054201 0.5740022172949 0.86632958108915 0.899821704069401 GO:0000287 magnesium ion binding 1/176 230/18639 0.00434782608695652 0.460449604743083 0.888718211739496 0.918342152130812 GO:0005085 guanyl-nucleotide exchange factor activity 1/176 230/18639 0.00434782608695652 0.460449604743083 0.888718211739496 0.918342152130812 GO:0005125 cytokine activity 1/176 234/18639 0.00427350427350427 0.452578671328671 0.892913563591861 0.92031756042844 GO:0016887 ATP hydrolysis activity 2/176 417/18639 0.00479616306954436 0.507930019620667 0.907319830517779 0.932780335965982 GO:0005096 GTPase activator activity 1/176 271/18639 0.003690036900369 0.390787487420329 0.924979079101951 0.946003179463531 GO:0016791 phosphatase activity 1/176 273/18639 0.00366300366300366 0.387924575424575 0.926409913162879 0.946003179463531 GO:0005216 monoatomic ion channel activity 2/176 448/18639 0.00446428571428571 0.472783076298701 0.927223960020087 0.946003179463531 GO:0031267 small GTPase binding 1/176 283/18639 0.00353356890459364 0.374216993254096 0.933167115319345 0.949662493620445 GO:0001664 G protein-coupled receptor binding 1/176 297/18639 0.00336700336700337 0.356577134986226 0.94160294158517 0.955833716520966 GO:0030695 GTPase regulator activity 2/176 489/18639 0.00408997955010225 0.433142777467931 0.947433929041638 0.957355485294118 GO:0060589 nucleoside-triphosphatase regulator activity 2/176 490/18639 0.00408163265306122 0.432258812615956 0.947853197598891 0.957355485294118 GO:0140097 catalytic activity, acting on DNA 1/176 336/18639 0.00297619047619048 0.315188717532468 0.959921361811853 0.967120772025442 GO:0042578 phosphoric ester hydrolase activity 1/176 363/18639 0.00275482093663912 0.291744928625094 0.969130421484175 0.973963989671129 GO:0140098 catalytic activity, acting on RNA 1/176 387/18639 0.00258397932816537 0.27365221987315 0.975531627578653 0.977958323169645 GO:0004175 endopeptidase activity 1/176 405/18639 0.00246913580246914 0.261489898989899 0.979449456192253 0.979449456192253