category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	10/35	138/9376	19.4120082815735	MT-CO3/MT-CYB/MT-CO1/MT-ATP6/MT-CO2/MT-ND4/MT-ND1/MT-ND2/MT-ND3/MT-ND5	13.3375082216391
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	11/35	235/9376	12.5393313069909	MT-CO3/MT-CYB/MT-CO1/MT-ATP6/MT-CO2/MT-ND4/MT-ND1/ACTB/MT-ND2/MT-ND3/MT-ND5	10.9658094150315
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	10/35	205/9376	13.0675958188153	MT-CO3/MT-CYB/MT-CO1/MT-ATP6/MT-CO2/MT-ND4/MT-ND1/MT-ND2/MT-ND3/MT-ND5	10.6933138602088
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	11/35	275/9376	10.7154285714286	MT-CO3/MT-CYB/MT-CO1/MT-ATP6/MT-CO2/MT-ND4/MT-ND1/MT-ND2/MT-ND3/MT-ND5/C1QA	10.0093696271346
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	12/35	368/9376	8.73540372670807	MT-CO3/MT-CYB/MT-CO1/MT-ATP6/MT-CO2/MT-ND4/MT-ND1/ACTB/MT-ND2/PFN1/MT-ND3/MT-ND5	9.26649893732691
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	10/35	227/9376	11.8011327879169	MT-CO3/MT-CYB/MT-CO1/MT-ATP6/MT-CO2/MT-ND4/MT-ND1/MT-ND2/MT-ND3/MT-ND5	10.0836646591587
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	10/35	268/9376	9.99573560767591	MT-CO3/MT-CYB/MT-CO1/MT-ATP6/MT-CO2/MT-ND4/MT-ND1/MT-ND2/MT-ND3/MT-ND5	9.14567034142051
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	10/35	308/9376	8.69758812615955	MT-CO3/MT-CYB/MT-CO1/MT-ATP6/MT-CO2/MT-ND4/MT-ND1/MT-ND2/MT-ND3/MT-ND5	8.40808796285317
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	10/35	388/9376	6.90427098674521	MT-CO3/MT-CYB/MT-CO1/MT-ATP6/MT-CO2/MT-ND4/MT-ND1/MT-ND2/MT-ND3/MT-ND5	7.27065583392467
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	10/35	480/9376	5.58095238095238	MT-CO3/MT-CYB/MT-CO1/MT-ATP6/MT-CO2/MT-ND4/MT-ND1/MT-ND2/MT-ND3/MT-ND5	6.30669724730072
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	5/35	149/9376	8.98945349952061	MT-ND4/MT-ND1/MT-ND2/MT-ND3/MT-ND5	6.01731742049128
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	4/35	87/9376	12.3165845648604	MT-CO3/MT-CYB/MT-CO1/MT-CO2	6.4910281461665
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	5/35	233/9376	5.74862047823421	ACTB/TLN1/FN1/FBLN1/MYOM2	4.49287189772545
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	5/35	238/9376	5.62785114045618	RPL13A/RPS4Y1/RPS20/C1QA/F13A1	4.42654880581047
NA	NA	hsa04518	Integrin signaling	4/35	154/9376	6.95807050092764	ACTB/SPP1/TLN1/FN1	4.5632726031881
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	4/35	157/9376	6.82511373976342	MT-CO3/MT-CYB/MT-CO1/MT-CO2	4.50542020924889
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	4/35	203/9376	5.27853624208304	ACTB/SPP1/TLN1/FN1	3.77233724623785
Organismal Systems	Immune system	hsa04611	Platelet activation	3/35	126/9376	6.37823129251701	ACTB/FCER1G/TLN1	3.72029052194975
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/35	65/9376	8.24263736263736	SPP1/CGA	3.58656106900012
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/35	78/9376	6.86886446886447	ACTB/FN1	3.18588125857603
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/35	88/9376	6.08831168831169	C1QA/F13A1	2.93546504695268
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/35	89/9376	6.0199036918138	SPP1/FN1	2.91256509200286
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	3/35	212/9376	3.79083557951482	ACTB/PFN1/TLN1	2.51583766989539
Genetic Information Processing	Translation	hsa03010	Ribosome	3/35	222/9376	3.62007722007722	RPL13A/RPS4Y1/RPS20	2.4182884338598
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	3/35	232/9376	3.464039408867	ACTB/PFN1/FN1	2.32619708713965
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/35	103/9376	5.20166435506241	CCL3/C1QA	2.62453768557118
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	2/35	109/9376	4.91533420707733	SPP1/CCL3	2.51672336163371
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	3/35	253/9376	3.17651044607566	ACTB/PFN1/TLN1	2.14820218196849
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/35	133/9376	4.02835660580021	TYROBP/FCER1G	2.15302628911641
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/35	138/9376	3.8824016563147	ACTB/FN1	2.08798818690723
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/35	142/9376	3.77303822937626	ACTB/GSTP1	2.03811210433433
Human Diseases	Immune disease	hsa05310	Asthma	1/35	32/9376	8.37142857142857	FCER1G	2.5567202442607
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/35	155/9376	3.45658986175115	ACTB/CORO1A	1.8876977910075
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/35	157/9376	3.41255686988171	C1QA/TMEM30A	1.86598630741393
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/35	37/9376	7.24015444015444	HBB	2.32792501452455
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/35	170/9376	3.15159663865546	ACTB/GSTP1	1.73289722747024
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/35	42/9376	6.37823129251701	FTL	2.13822398347072
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/35	181/9376	2.96006314127861	FCER1G/CORO1A	1.62988310089232
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	3/35	362/9376	2.22004735595896	SPP1/CSH1/FN1	1.44908937059641
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/35	46/9376	5.82360248447205	FTL	2.00739380008839
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/35	50/9376	5.35771428571429	HBB	1.89111971937103
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/35	51/9376	5.25266106442577	PAFAH1B2	1.86399358388701
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/35	51/9376	5.25266106442577	ACTB	1.86399358388701
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	2/35	204/9376	2.62633053221289	ACTB/FN1	1.43752316015491
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/35	52/9376	5.15164835164835	CGA	1.83757077430382
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/35	52/9376	5.15164835164835	PLTP	1.83757077430382
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/35	54/9376	4.96084656084656	CGA	1.78670693687101
NA	NA	hsa04081	Hormone signaling	2/35	219/9376	2.44644487932159	CSH1/CGA	1.32577648876726
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/35	59/9376	4.54043583535109	GSTP1	1.66981231745146
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/35	59/9376	4.54043583535109	CGA	1.66981231745146
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/35	61/9376	4.39156908665105	FTL	1.62666128456513
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/35	69/9376	3.8824016563147	FCER1G	1.47094746254932
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/35	70/9376	3.8269387755102	GSTP1	1.45313804429665
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/35	70/9376	3.8269387755102	ACTB	1.45313804429665
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/35	71/9376	3.77303822937626	CGA	1.43565410411096
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	2/35	248/9376	2.16036866359447	ACTB/PFN1	1.13359257065319
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/35	73/9376	3.66966731898239	GSTP1	1.40161920308092
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/35	75/9376	3.57180952380952	GSTP1	1.36876087928979
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/35	75/9376	3.57180952380952	CGA	1.36876087928979
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/35	76/9376	3.52481203007519	PLTP	1.35274939083119
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/35	76/9376	3.52481203007519	ACTB	1.35274939083119
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/35	78/9376	3.43443223443223	C1QA	1.32151834006343
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/35	79/9376	3.39095840867993	GSTP1	1.30628255199797
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/35	82/9376	3.26689895470383	GSTP1	1.26200399196201
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/35	86/9376	3.11495016611296	ACTB	1.20604769130185
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/35	93/9376	2.88049155145929	ACTB	1.11555672843487
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/35	93/9376	2.88049155145929	CGA	1.11555672843487
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/35	93/9376	2.88049155145929	FN1	1.11555672843487
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/35	95/9376	2.81984962406015	CCL3	1.09124657576202
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/35	298/9376	1.79789069990412	CSH1/CCL3	0.856799925774349
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/35	99/9376	2.70591630591631	C1QA	1.04446649679407
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/35	99/9376	2.70591630591631	ACTB	1.04446649679407
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/35	100/9376	2.67885714285714	CCL3	1.03313326943114
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/35	101/9376	2.65233380480905	FN1	1.02193786310199
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/35	103/9376	2.60083217753121	FN1	0.999947645304765
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/35	105/9376	2.5512925170068	FCER1G	0.978471163084217
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/35	105/9376	2.5512925170068	ACTB	0.978471163084217
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/35	106/9376	2.52722371967655	GSTP1	0.967918298922329
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/35	116/9376	2.30935960591133	ACTB	0.86857117866197
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	2/35	333/9376	1.60892320892321	SPP1/FN1	0.692550349920481
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/35	117/9376	2.28962148962149	ACTB	0.859203672271387
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/35	122/9376	2.19578454332553	ACTB	0.813750142323961
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/35	122/9376	2.19578454332553	CSH1	0.813750142323961
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/35	125/9376	2.14308571428571	FCER1G	0.787521533223956
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/35	137/9376	1.95537017726799	ACTB	0.689512993490857
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	2/35	370/9376	1.44803088803089	CSH1/CGA	0.538227422450886
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/35	140/9376	1.9134693877551	SPP1	0.666559661745999
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/35	142/9376	1.88651911468813	TYROBP	0.651568852974682
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/35	143/9376	1.87332667332667	C1QA	0.644163777439994
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/35	144/9376	1.86031746031746	C1QA	0.63681760276293
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/35	149/9376	1.79789069990412	FCER1G	0.600937424376916
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	1/35	154/9376	1.73951762523191	ACTB	0.56639486193896
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/35	157/9376	1.70627843494086	ACTB	0.546269356496452
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/35	168/9376	1.59455782312925	FTL	0.475980386996307
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/35	168/9376	1.59455782312925	CSH1	0.475980386996307
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/35	170/9376	1.57579831932773	ACTB	0.463748312866196
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/35	173/9376	1.54847233691164	ACTB	0.445693235874684
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/35	193/9376	1.3880088823094	CCL3	0.333388798770939
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/35	194/9376	1.38085419734904	ACTB	0.328105825516041
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/35	195/9376	1.37377289377289	ACTB	0.322851708667459
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/35	200/9376	1.33942857142857	ACTB	0.29700219980444
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/35	216/9376	1.24021164021164	CCL3	0.21862315718848
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	1/35	224/9376	1.19591836734694	TLN1	0.181662016549195
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/35	226/9376	1.18533501896334	CGA	0.172633125592417
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/35	227/9376	1.18011327879169	CCL3	0.168149206167408
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/35	250/9376	1.07154285714286	DAB2	0.0701809150823222
NA	NA	hsa04517	IgSF CAM signaling	1/35	299/9376	0.895938843764931	ACTB	-0.111937614609919
NA	NA	hsa04519	Cadherin signaling	1/35	404/9376	0.663083451202263	ACTB	-0.423732102322195