ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	64/721	175/18639	0.365714285714286	9.45429760253616	2.42364602555971e-45	2.17885777697818e-42
GO:0009055	electron transfer activity	26/721	116/18639	0.224137931034483	5.79432301879573	2.55141031918304e-13	1.14685893847278e-10
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	20/721	68/18639	0.294117647058824	7.6034102961573	6.21006240372201e-13	1.86094870031536e-10
GO:0140375	immune receptor activity	29/721	156/18639	0.185897435897436	4.80574522564814	1.68879234271554e-12	3.79556079025318e-10
GO:0015078	proton transmembrane transporter activity	31/721	185/18639	0.167567567567568	4.33188889305394	5.02374909558658e-12	9.03270087386467e-10
GO:0022853	active monoatomic ion transmembrane transporter activity	24/721	118/18639	0.203389830508475	5.2579515268342	1.93545827686102e-11	2.89996165149677e-09
GO:0023023	MHC protein complex binding	14/721	37/18639	0.378378378378378	9.78168459721858	3.96404046042336e-11	5.09096053417229e-09
GO:0023026	MHC class II protein complex binding	12/721	27/18639	0.444444444444444	11.4895977808599	1.04508231805322e-10	1.17441125491231e-08
GO:0015399	primary active transmembrane transporter activity	26/721	166/18639	0.156626506024096	4.04904500108618	1.199682151447e-09	1.19834917127873e-07
GO:0042277	peptide binding	31/721	249/18639	0.124497991967871	3.21847166753004	9.8554750915787e-09	8.86007210732925e-07
GO:0038024	cargo receptor activity	15/721	65/18639	0.230769230769231	5.96575269390803	1.9252888976358e-08	1.57348610815871e-06
GO:0008137	NADH dehydrogenase (ubiquinone) activity	12/721	41/18639	0.292682926829268	7.56632048983458	2.88361522895787e-08	2.16030840902761e-06
GO:0019955	cytokine binding	22/721	144/18639	0.152777777777778	3.9495492371706	3.58693435507843e-08	2.48050306555039e-06
GO:0003954	NADH dehydrogenase activity	12/721	44/18639	0.272727272727273	7.05043500189131	6.92044905025662e-08	4.44391692584336e-06
GO:0042605	peptide antigen binding	12/721	45/18639	0.266666666666667	6.89375866851595	9.10735682738878e-08	5.45834252521501e-06
GO:0019843	rRNA binding	14/721	65/18639	0.215384615384615	5.5680358476475	1.44883714819535e-07	8.14065372642261e-06
GO:0016651	oxidoreductase activity, acting on NAD(P)H	16/721	88/18639	0.181818181818182	4.70029000126087	2.2916560702631e-07	1.21188165127443e-05
GO:0042608	T cell receptor binding	6/721	11/18639	0.545454545454545	14.1008700037826	1.2837628379393e-06	6.07422521740753e-05
GO:1990948	ubiquitin ligase inhibitor activity	6/721	11/18639	0.545454545454545	14.1008700037826	1.2837628379393e-06	6.07422521740753e-05
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	12/721	58/18639	0.206896551724138	5.34860586350375	1.78008374775005e-06	8.00147644613649e-05
GO:0005201	extracellular matrix structural constituent	21/721	168/18639	0.125	3.23144937586685	2.21446829336643e-06	9.48003331303058e-05
GO:0005044	scavenger receptor activity	8/721	27/18639	0.296296296296296	7.65973185390661	5.56772923037351e-06	0.000227517662641172
GO:0005539	glycosaminoglycan binding	25/721	242/18639	0.103305785123967	2.67061931889822	8.22431257004326e-06	0.000321463347846473
GO:0001784	phosphotyrosine residue binding	10/721	47/18639	0.212765957446809	5.50033936317762	9.96511723737953e-06	0.000360039354991479
GO:0003779	actin binding	37/721	443/18639	0.0835214446952596	2.15916256265595	1.00122178807419e-05	0.000360039354991479
GO:0038187	pattern recognition receptor activity	10/721	48/18639	0.208333333333333	5.38574895977809	1.21553087649205e-05	0.000390849512414343
GO:0004129	cytochrome-c oxidase activity	6/721	15/18639	0.4	10.3406380027739	1.21732884845401e-05	0.000390849512414343
GO:0055105	ubiquitin-protein transferase inhibitor activity	6/721	15/18639	0.4	10.3406380027739	1.21732884845401e-05	0.000390849512414343
GO:0051219	phosphoprotein binding	14/721	93/18639	0.150537634408602	3.8916379580332	1.29511913335758e-05	0.000401486931340849
GO:0045309	protein phosphorylated amino acid binding	11/721	59/18639	0.186440677966102	4.81978889959802	1.3810445161347e-05	0.000413853006668366
GO:0001540	amyloid-beta binding	13/721	83/18639	0.156626506024096	4.04904500108618	1.69553091371228e-05	0.000491703964976563
GO:0032395	MHC class II receptor activity	5/721	10/18639	0.5	12.9257975034674	1.83072076184016e-05	0.000498166558960814
GO:0005518	collagen binding	12/721	72/18639	0.166666666666667	4.30859916782247	1.86840497046274e-05	0.000498166558960814
GO:0016675	oxidoreductase activity, acting on a heme group of donors	6/721	16/18639	0.375	9.69434812760056	1.88405595157594e-05	0.000498166558960814
GO:0019838	growth factor binding	17/721	136/18639	0.125	3.23144937586685	2.01752930145698e-05	0.000518216812002806
GO:0051015	actin filament binding	22/721	209/18639	0.105263157894737	2.72122052704577	2.11286093814219e-05	0.000527628328719398
GO:0016209	antioxidant activity	13/721	86/18639	0.151162790697674	3.90779924523433	2.5081282093232e-05	0.000609407367616636
GO:0030169	low-density lipoprotein particle binding	6/721	17/18639	0.352941176470588	9.12409235538876	2.81660750514517e-05	0.000666350038717238
GO:0019864	IgG binding	5/721	11/18639	0.454545454545455	11.7507250031522	3.24934116021202e-05	0.000730289425757651
GO:0050786	RAGE receptor binding	5/721	11/18639	0.454545454545455	11.7507250031522	3.24934116021202e-05	0.000730289425757651
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	6/721	18/18639	0.333333333333333	8.61719833564494	4.08699741755161e-05	0.000896148945946072
GO:0004875	complement receptor activity	5/721	12/18639	0.416666666666667	10.7714979195562	5.3929162264104e-05	0.00115434087798642
GO:0004601	peroxidase activity	10/721	57/18639	0.175438596491228	4.53536754507628	5.86289600761109e-05	0.00122575430484706
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	10/721	59/18639	0.169491525423729	4.38162627236183	7.95633635213723e-05	0.00162562417740258
GO:0032396	inhibitory MHC class I receptor activity	5/721	13/18639	0.384615384615385	9.94292115651339	8.48468406428115e-05	0.00169505132750861
GO:0005178	integrin binding	17/721	161/18639	0.105590062111801	2.72967152247138	0.000171429311919119	0.00335032503076712
GO:0071813	lipoprotein particle binding	7/721	32/18639	0.21875	5.65503640776699	0.000181794253034227	0.0034048548641202
GO:0071814	protein-lipid complex binding	7/721	32/18639	0.21875	5.65503640776699	0.000181794253034227	0.0034048548641202
GO:0005523	tropomyosin binding	5/721	15/18639	0.333333333333333	8.61719833564494	0.000185596829944634	0.00340513367592297
GO:0030020	extracellular matrix structural constituent conferring tensile strength	8/721	44/18639	0.181818181818182	4.70029000126087	0.000248508230298738	0.00445376376381949
GO:0033218	amide binding	22/721	247/18639	0.0890688259109312	2.30257121519257	0.000252660680706111	0.00445376376381949
GO:0008201	heparin binding	17/721	172/18639	0.0988372093023256	2.55509950649937	0.000376912644157774	0.00644102367440735
GO:0016175	superoxide-generating NAD(P)H oxidase activity	4/721	10/18639	0.4	10.3406380027739	0.000386891299686315	0.00644102367440735
GO:0031720	haptoglobin binding	4/721	10/18639	0.4	10.3406380027739	0.000386891299686315	0.00644102367440735
GO:0003823	antigen binding	17/721	174/18639	0.0977011494252874	2.52573054665455	0.00043128817096065	0.00704960119442953
GO:0032393	MHC class I receptor activity	5/721	18/18639	0.277777777777778	7.18099861303745	0.000480767730823447	0.00763287659410945
GO:0015252	proton channel activity	6/721	27/18639	0.222222222222222	5.74479889042996	0.00048395324345299	0.00763287659410945
GO:0001851	complement component C3b binding	4/721	11/18639	0.363636363636364	9.40058000252175	0.000589404378591567	0.00898092434497998
GO:0048407	platelet-derived growth factor binding	4/721	11/18639	0.363636363636364	9.40058000252175	0.000589404378591567	0.00898092434497998
GO:0045296	cadherin binding	26/721	334/18639	0.0778443113772455	2.01239961131828	0.000601166569335266	0.00900747909720673
GO:0022804	active transmembrane transporter activity	32/721	457/18639	0.0700218818380744	1.81017733090134	0.000936030834577624	0.013794946234185
GO:0005543	phospholipid binding	34/721	497/18639	0.06841046277666	1.7685195779392	0.000982990562616527	0.0142533631579396
GO:0048306	calcium-dependent protein binding	10/721	80/18639	0.125	3.23144937586685	0.00100670202271654	0.0143654780701931
GO:0001846	opsonin binding	5/721	21/18639	0.238095238095238	6.15514166831781	0.0010369697129474	0.0145661839365579
GO:1901681	sulfur compound binding	22/721	275/18639	0.08	2.06812760055479	0.00108057490432063	0.0149451821382192
GO:0035325	Toll-like receptor binding	4/721	13/18639	0.307692307692308	7.95433692521071	0.0012003842739164	0.0163506888219825
GO:0008135	translation factor activity, RNA binding	10/721	83/18639	0.120481927710843	3.11465000083552	0.00134090598068043	0.0179921563676374
GO:0030695	GTPase regulator activity	33/721	489/18639	0.0674846625766871	1.74458616611217	0.00145100048875087	0.018995025735353
GO:0180051	translation factor activity	10/721	84/18639	0.119047619047619	3.07757083415891	0.00147051485559547	0.018995025735353
GO:0019956	chemokine binding	6/721	33/18639	0.181818181818182	4.70029000126087	0.00148665919512186	0.018995025735353
GO:0060589	nucleoside-triphosphatase regulator activity	33/721	490/18639	0.0673469387755102	1.74102578618132	0.0015001633228143	0.018995025735353
GO:0004602	glutathione peroxidase activity	5/721	23/18639	0.217391304347826	5.61991195802931	0.00160834121760689	0.019531343052526
GO:0031625	ubiquitin protein ligase binding	23/721	302/18639	0.076158940397351	1.96883008330961	0.00161719210369209	0.019531343052526
GO:0005344	oxygen carrier activity	4/721	14/18639	0.285714285714286	7.38617000198137	0.00162942239036646	0.019531343052526
GO:0019763	immunoglobulin receptor activity	4/721	14/18639	0.285714285714286	7.38617000198137	0.00162942239036646	0.019531343052526
GO:0048027	mRNA 5'-UTR binding	5/721	24/18639	0.208333333333333	5.38574895977809	0.00196765577586515	0.0232752966118786
GO:0005504	fatty acid binding	7/721	47/18639	0.148936170212766	3.85023755422433	0.002055643990582	0.0240003110069249
GO:0031386	protein tag activity	4/721	15/18639	0.266666666666667	6.89375866851595	0.00215444986688349	0.024517094054788
GO:0141047	molecular tag activity	4/721	15/18639	0.266666666666667	6.89375866851595	0.00215444986688349	0.024517094054788
GO:0055106	ubiquitin-protein transferase regulator activity	6/721	36/18639	0.166666666666667	4.30859916782247	0.00236980256524583	0.0262110779875831
GO:0001848	complement binding	5/721	25/18639	0.2	5.17031900138696	0.00238224860605143	0.0262110779875831
GO:0002020	protease binding	13/721	136/18639	0.0955882352941176	2.47110834625112	0.00239077685759935	0.0262110779875831
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	4/721	16/18639	0.25	6.4628987517337	0.00278546811094964	0.0298638002077814
GO:0019865	immunoglobulin binding	5/721	26/18639	0.192307692307692	4.9714605782567	0.00285682627126719	0.0298638002077814
GO:0030247	polysaccharide binding	5/721	26/18639	0.192307692307692	4.9714605782567	0.00285682627126719	0.0298638002077814
GO:0050750	low-density lipoprotein particle receptor binding	5/721	26/18639	0.192307692307692	4.9714605782567	0.00285682627126719	0.0298638002077814
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	4/721	17/18639	0.235294117647059	6.08272823692584	0.0035322047883088	0.0360846830078365
GO:0015278	intracellularly gated calcium channel activity	4/721	17/18639	0.235294117647059	6.08272823692584	0.0035322047883088	0.0360846830078365
GO:0044389	ubiquitin-like protein ligase binding	23/721	322/18639	0.0714285714285714	1.84654250049534	0.00363469661825516	0.0367145197731617
GO:0004896	cytokine receptor activity	10/721	96/18639	0.104166666666667	2.69287447988904	0.00397627937597987	0.0396029085177087
GO:0001618	virus receptor activity	9/721	81/18639	0.111111111111111	2.87239944521498	0.00400874824817741	0.0396029085177087
GO:0140272	exogenous protein binding	9/721	82/18639	0.109756097560976	2.83737018368797	0.00435247442755224	0.042531244677929
GO:0030228	lipoprotein particle receptor activity	4/721	18/18639	0.222222222222222	5.74479889042996	0.00440404394759033	0.0425724248267065
GO:0001530	lipopolysaccharide binding	6/721	41/18639	0.146341463414634	3.78316024491729	0.00464679634412469	0.0435153115975844
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	6/721	41/18639	0.146341463414634	3.78316024491729	0.00464679634412469	0.0435153115975844
GO:0042287	MHC protein binding	6/721	41/18639	0.146341463414634	3.78316024491729	0.00464679634412469	0.0435153115975844
GO:0017124	SH3 domain binding	11/721	115/18639	0.0956521739130435	2.4727612615329	0.00498751750567366	0.0462245179134084
GO:0042056	chemoattractant activity	6/721	42/18639	0.142857142857143	3.69308500099069	0.00524760464370222	0.0479522059569499
GO:0005126	cytokine receptor binding	20/721	275/18639	0.0727272727272727	1.88011600050435	0.00528060999970861	0.0479522059569499
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	5/721	30/18639	0.166666666666667	4.30859916782247	0.00544933431074121	0.0489895154535635
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/721	10/18639	0.3	7.75547850208044	0.00564123133718766	0.049544780318392
GO:0005381	iron ion transmembrane transporter activity	3/721	10/18639	0.3	7.75547850208044	0.00564123133718766	0.049544780318392
GO:1990782	protein tyrosine kinase binding	11/721	117/18639	0.094017094017094	2.43049183825883	0.00567643200533301	0.049544780318392
GO:0016504	peptidase activator activity	7/721	57/18639	0.12280701754386	3.1747572815534	0.00619997770914764	0.0535940380819589
GO:0070325	lipoprotein particle receptor binding	5/721	31/18639	0.161290322580645	4.16961209789271	0.00629433398941832	0.0538914881570197
GO:0030246	carbohydrate binding	20/721	280/18639	0.0714285714285714	1.84654250049534	0.00641732008314146	0.0544261391956997
GO:0016004	phospholipase activator activity	4/721	20/18639	0.2	5.17031900138696	0.00655850237339687	0.0551036788194746
GO:0004715	non-membrane spanning protein tyrosine kinase activity	6/721	45/18639	0.133333333333333	3.44687933425797	0.00739097248733379	0.0609585712487438
GO:0008009	chemokine activity	6/721	45/18639	0.133333333333333	3.44687933425797	0.00739097248733379	0.0609585712487438
GO:0016176	superoxide-generating NADPH oxidase activator activity	3/721	11/18639	0.272727272727273	7.05043500189131	0.00753566644666121	0.0615869466868039
GO:0015026	coreceptor activity	7/721	61/18639	0.114754098360656	2.96657647620563	0.00896429707440184	0.0726027303593446
GO:0061133	endopeptidase activator activity	4/721	22/18639	0.181818181818182	4.70029000126087	0.00931502950298563	0.074769745742715
GO:0097371	MDM2/MDM4 family protein binding	3/721	12/18639	0.25	6.4628987517337	0.00976184126662982	0.0776627902539842
GO:0033293	monocarboxylic acid binding	8/721	79/18639	0.10126582278481	2.61788303867694	0.0112331582243429	0.0885842916112653
GO:0004857	enzyme inhibitor activity	26/721	416/18639	0.0625	1.61572468793343	0.011472815941458	0.0896874915771366
GO:0008035	high-density lipoprotein particle binding	3/721	13/18639	0.230769230769231	5.96575269390803	0.0123302783644438	0.0931505903330674
GO:0017154	semaphorin receptor activity	3/721	13/18639	0.230769230769231	5.96575269390803	0.0123302783644438	0.0931505903330674
GO:0043560	insulin receptor substrate binding	3/721	13/18639	0.230769230769231	5.96575269390803	0.0123302783644438	0.0931505903330674
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	3/721	13/18639	0.230769230769231	5.96575269390803	0.0123302783644438	0.0931505903330674
GO:0005540	hyaluronic acid binding	4/721	24/18639	0.166666666666667	4.30859916782247	0.0127314570784001	0.0945915695329067
GO:0060229	lipase activator activity	4/721	24/18639	0.166666666666667	4.30859916782247	0.0127314570784001	0.0945915695329067
GO:1901981	phosphatidylinositol phosphate binding	14/721	185/18639	0.0756756756756757	1.95633691944372	0.0129498000187684	0.0946893355234611
GO:0030971	receptor tyrosine kinase binding	8/721	81/18639	0.0987654320987654	2.5532439513022	0.0129552705999841	0.0946893355234611
GO:0043394	proteoglycan binding	5/721	37/18639	0.135135135135135	3.49345878472092	0.0133581533924739	0.0967865342207152
GO:0003743	translation initiation factor activity	6/721	51/18639	0.117647058823529	3.04136411846292	0.013457527005105	0.0967865342207152
GO:0050840	extracellular matrix binding	7/721	67/18639	0.104477611940299	2.70091291117229	0.0146669585803984	0.103240682425854
GO:0120020	cholesterol transfer activity	4/721	25/18639	0.16	4.13625520110957	0.014702734882657	0.103240682425854
GO:0000146	microfilament motor activity	5/721	38/18639	0.131578947368421	3.40152565880721	0.0149054066596855	0.103240682425854
GO:0005516	calmodulin binding	15/721	207/18639	0.072463768115942	1.87330398600977	0.0149086839451233	0.103240682425854
GO:0061134	peptidase regulator activity	16/721	226/18639	0.0707964601769911	1.83020141642016	0.0149291309403348	0.103240682425854
GO:0005085	guanyl-nucleotide exchange factor activity	16/721	230/18639	0.0695652173913043	1.79837182656938	0.0173472190631949	0.11904694609017
GO:0005041	low-density lipoprotein particle receptor activity	3/721	15/18639	0.2	5.17031900138696	0.0185222545709058	0.125199299693566
GO:0017081	chloride channel regulator activity	3/721	15/18639	0.2	5.17031900138696	0.0185222545709058	0.125199299693566
GO:0004364	glutathione transferase activity	4/721	27/18639	0.148148148148148	3.82986592695331	0.0191974792053371	0.128795028399985
GO:0004713	protein tyrosine kinase activity	11/721	140/18639	0.0785714285714286	2.03119675054488	0.0201484361430922	0.133876356650555
GO:0042169	SH2 domain binding	5/721	41/18639	0.121951219512195	3.15263353743107	0.0202527080138771	0.133876356650555
GO:0004197	cysteine-type endopeptidase activity	8/721	88/18639	0.0909090909090909	2.35014500063044	0.0205124886773976	0.134603849058252
GO:0051020	GTPase binding	20/721	315/18639	0.0634920634920635	1.64137111155142	0.0211104741020863	0.137524030563591
GO:0097718	disordered domain specific binding	4/721	28/18639	0.142857142857143	3.69308500099069	0.0217295857476502	0.140538831562141
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/721	16/18639	0.1875	4.84717406380028	0.0221538206770495	0.142259177061911
GO:0001664	G protein-coupled receptor binding	19/721	297/18639	0.063973063973064	1.65380574118438	0.0225599043752228	0.143839390307272
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	4/721	29/18639	0.137931034482759	3.56573724233584	0.0244562880314787	0.153749670911184
GO:0099604	ligand-gated calcium channel activity	4/721	29/18639	0.137931034482759	3.56573724233584	0.0244562880314787	0.153749670911184
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/721	17/18639	0.176470588235294	4.56204617769438	0.0261441669389225	0.158808149176293
GO:0008429	phosphatidylethanolamine binding	3/721	17/18639	0.176470588235294	4.56204617769438	0.0261441669389225	0.158808149176293
GO:0019198	transmembrane receptor protein phosphatase activity	3/721	17/18639	0.176470588235294	4.56204617769438	0.0261441669389225	0.158808149176293
GO:0036041	long-chain fatty acid binding	3/721	17/18639	0.176470588235294	4.56204617769438	0.0261441669389225	0.158808149176293
GO:0048038	quinone binding	3/721	17/18639	0.176470588235294	4.56204617769438	0.0261441669389225	0.158808149176293
GO:0061135	endopeptidase regulator activity	13/721	184/18639	0.0706521739130435	1.82647138635952	0.0268733937028838	0.162142153952299
GO:0001968	fibronectin binding	4/721	30/18639	0.133333333333333	3.44687933425797	0.0273804347577459	0.163523761925039
GO:0098631	cell adhesion mediator activity	7/721	76/18639	0.0921052631578947	2.38106796116505	0.0274661713578209	0.163523761925039
GO:0035091	phosphatidylinositol binding	18/721	284/18639	0.0633802816901408	1.63848137367897	0.0280909285765144	0.166143057830832
GO:0031406	carboxylic acid binding	13/721	187/18639	0.0695187165775401	1.79716970636445	0.0301203789065737	0.175721026871365
GO:0003746	translation elongation factor activity	3/721	18/18639	0.166666666666667	4.30859916782247	0.030492191537189	0.175721026871365
GO:0035615	clathrin adaptor activity	3/721	18/18639	0.166666666666667	4.30859916782247	0.030492191537189	0.175721026871365
GO:0070064	proline-rich region binding	3/721	18/18639	0.166666666666667	4.30859916782247	0.030492191537189	0.175721026871365
GO:0043177	organic acid binding	13/721	189/18639	0.0687830687830688	1.77815203751403	0.0324376744595709	0.185741842924549
GO:0019902	phosphatase binding	13/721	190/18639	0.068421052631579	1.76879334257975	0.0336433577965635	0.190604835508168
GO:0120015	sterol transfer activity	4/721	32/18639	0.125	3.23144937586685	0.0338296034776194	0.190604835508168
GO:0035401	histone H3Y41 kinase activity	9/721	115/18639	0.0782608695652174	2.02316830489055	0.0343732710260849	0.190604835508168
GO:0140801	histone H2AXY142 kinase activity	9/721	115/18639	0.0782608695652174	2.02316830489055	0.0343732710260849	0.190604835508168
GO:0005096	GTPase activator activity	17/721	271/18639	0.0627306273062731	1.62168677165274	0.0349721052387656	0.190604835508168
GO:0008301	DNA binding, bending	3/721	19/18639	0.157894736842105	4.08183079056866	0.0351951086700288	0.190604835508168
GO:0015245	fatty acid transmembrane transporter activity	3/721	19/18639	0.157894736842105	4.08183079056866	0.0351951086700288	0.190604835508168
GO:0034987	immunoglobulin receptor binding	3/721	19/18639	0.157894736842105	4.08183079056866	0.0351951086700288	0.190604835508168
GO:0042834	peptidoglycan binding	3/721	19/18639	0.157894736842105	4.08183079056866	0.0351951086700288	0.190604835508168
GO:0005125	cytokine activity	15/721	234/18639	0.0641025641025641	1.65715352608556	0.0389572347112185	0.209715892247817
GO:0001614	purinergic nucleotide receptor activity	3/721	20/18639	0.15	3.87773925104022	0.0402486274282579	0.211599509111134
GO:0016502	nucleotide receptor activity	3/721	20/18639	0.15	3.87773925104022	0.0402486274282579	0.211599509111134
GO:0016505	peptidase activator activity involved in apoptotic process	3/721	20/18639	0.15	3.87773925104022	0.0402486274282579	0.211599509111134
GO:0042288	MHC class I protein binding	3/721	20/18639	0.15	3.87773925104022	0.0402486274282579	0.211599509111134
GO:0019825	oxygen binding	4/721	34/18639	0.117647058823529	3.04136411846292	0.0410886604593488	0.214759917168341
GO:0070851	growth factor receptor binding	10/721	139/18639	0.0719424460431655	1.85982697891617	0.0436244222948089	0.226695697358574
GO:0005154	epidermal growth factor receptor binding	4/721	35/18639	0.114285714285714	2.95446800079255	0.0450231837151801	0.232619782528431
GO:0072542	protein phosphatase activator activity	3/721	21/18639	0.142857142857143	3.69308500099069	0.0456471175781681	0.233163401720302
GO:0140312	cargo adaptor activity	3/721	21/18639	0.142857142857143	3.69308500099069	0.0456471175781681	0.233163401720302
GO:0005021	vascular endothelial growth factor receptor activity	5/721	51/18639	0.0980392156862745	2.5344700987191	0.0464889365145172	0.236121773596333
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/721	36/18639	0.111111111111111	2.87239944521498	0.0491607156500075	0.247059637222374
GO:0020037	heme binding	10/721	142/18639	0.0704225352112676	1.8205348596433	0.0491920745971134	0.247059637222374
GO:0005080	protein kinase C binding	5/721	52/18639	0.0961538461538462	2.48573028912835	0.0498675595952522	0.247684729702385
GO:0030159	signaling receptor complex adaptor activity	5/721	52/18639	0.0961538461538462	2.48573028912835	0.0498675595952522	0.247684729702385
GO:0008083	growth factor activity	11/721	162/18639	0.0679012345679012	1.75535521652027	0.0502838364951111	0.248380049500576
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/721	22/18639	0.136363636363636	3.52521750094566	0.0513837630637233	0.251054364099387
GO:0033691	sialic acid binding	3/721	22/18639	0.136363636363636	3.52521750094566	0.0513837630637233	0.251054364099387
GO:0019903	protein phosphatase binding	10/721	144/18639	0.0694444444444444	1.79524965325936	0.0531568875101846	0.256239726835974
GO:0019207	kinase regulator activity	17/721	287/18639	0.0592334494773519	1.53127914675224	0.054650760257641	0.256239726835974
GO:0005031	tumor necrosis factor receptor activity	2/721	10/18639	0.2	5.17031900138696	0.0547252809260368	0.256239726835974
GO:0005131	growth hormone receptor binding	2/721	10/18639	0.2	5.17031900138696	0.0547252809260368	0.256239726835974
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/721	10/18639	0.2	5.17031900138696	0.0547252809260368	0.256239726835974
GO:0042975	peroxisome proliferator activated receptor binding	2/721	10/18639	0.2	5.17031900138696	0.0547252809260368	0.256239726835974
GO:0043121	neurotrophin binding	2/721	10/18639	0.2	5.17031900138696	0.0547252809260368	0.256239726835974
GO:1905394	retromer complex binding	2/721	10/18639	0.2	5.17031900138696	0.0547252809260368	0.256239726835974
GO:0005158	insulin receptor binding	3/721	23/18639	0.130434782608696	3.37194717481758	0.0574507039940852	0.266227746859188
GO:0043274	phospholipase binding	3/721	23/18639	0.130434782608696	3.37194717481758	0.0574507039940852	0.266227746859188
GO:0043531	ADP binding	4/721	38/18639	0.105263157894737	2.72122052704577	0.0580410099903529	0.266715614307661
GO:0042826	histone deacetylase binding	9/721	127/18639	0.0708661417322835	1.83200279576703	0.0581493441649628	0.266715614307661
GO:0042379	chemokine receptor binding	6/721	72/18639	0.0833333333333333	2.15429958391123	0.0596909131129005	0.272396603494911
GO:0000217	DNA secondary structure binding	4/721	39/18639	0.102564102564103	2.6514456417369	0.0627807682519865	0.284589630424208
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3/721	24/18639	0.125	3.23144937586685	0.063839167839183	0.284589630424208
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	3/721	24/18639	0.125	3.23144937586685	0.063839167839183	0.284589630424208
GO:0046961	proton-transporting ATPase activity, rotational mechanism	3/721	24/18639	0.125	3.23144937586685	0.063839167839183	0.284589630424208
GO:0008199	ferric iron binding	2/721	11/18639	0.181818181818182	4.70029000126087	0.0652118619214536	0.284589630424208
GO:0008271	secondary active sulfate transmembrane transporter activity	2/721	11/18639	0.181818181818182	4.70029000126087	0.0652118619214536	0.284589630424208
GO:0010854	adenylate cyclase regulator activity	2/721	11/18639	0.181818181818182	4.70029000126087	0.0652118619214536	0.284589630424208
GO:0015173	aromatic amino acid transmembrane transporter activity	2/721	11/18639	0.181818181818182	4.70029000126087	0.0652118619214536	0.284589630424208
GO:0140031	phosphorylation-dependent protein binding	2/721	11/18639	0.181818181818182	4.70029000126087	0.0652118619214536	0.284589630424208
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	4/721	40/18639	0.1	2.58515950069348	0.0677175704961904	0.292683153250362
GO:0050997	quaternary ammonium group binding	4/721	40/18639	0.1	2.58515950069348	0.0677175704961904	0.292683153250362
GO:0043022	ribosome binding	8/721	112/18639	0.0714285714285714	1.84654250049534	0.0689088951496948	0.296407161433376
GO:0019211	phosphatase activator activity	3/721	25/18639	0.12	3.10219140083218	0.0705395905150729	0.300545459113984
GO:0042974	nuclear retinoic acid receptor binding	3/721	25/18639	0.12	3.10219140083218	0.0705395905150729	0.300545459113984
GO:0046906	tetrapyrrole binding	10/721	152/18639	0.0657894736842105	1.70076282940361	0.0711015840658449	0.301510962618843
GO:0051087	protein-folding chaperone binding	9/721	134/18639	0.0671641791044776	1.73630115718219	0.0759717470854604	0.319048267819182
GO:0005165	neurotrophin receptor binding	2/721	12/18639	0.166666666666667	4.30859916782247	0.0763018660524183	0.319048267819182
GO:0070008	serine-type exopeptidase activity	2/721	12/18639	0.166666666666667	4.30859916782247	0.0763018660524183	0.319048267819182
GO:0004435	phosphatidylinositol phospholipase C activity	3/721	26/18639	0.115384615384615	2.98287634695402	0.0775417280020347	0.319770704008391
GO:0008157	protein phosphatase 1 binding	3/721	26/18639	0.115384615384615	2.98287634695402	0.0775417280020347	0.319770704008391
GO:0043548	phosphatidylinositol 3-kinase binding	3/721	26/18639	0.115384615384615	2.98287634695402	0.0775417280020347	0.319770704008391
GO:0048487	beta-tubulin binding	4/721	42/18639	0.0952380952380952	2.46205666732713	0.0781719051171062	0.320897455252413
GO:0004714	transmembrane receptor protein tyrosine kinase activity	5/721	60/18639	0.0833333333333333	2.15429958391123	0.0819369027039863	0.334823979685835
GO:0008200	ion channel inhibitor activity	4/721	43/18639	0.0930232558139535	2.40479953552882	0.0836833519323036	0.33874223736522
GO:0048156	tau protein binding	4/721	43/18639	0.0930232558139535	2.40479953552882	0.0836833519323036	0.33874223736522
GO:0031267	small GTPase binding	16/721	283/18639	0.0565371024734982	1.46157427601045	0.0840261612151768	0.33874223736522
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/721	13/18639	0.153846153846154	3.97716846260536	0.0879330638138682	0.348245922328932
GO:0005035	death receptor activity	2/721	13/18639	0.153846153846154	3.97716846260536	0.0879330638138682	0.348245922328932
GO:0005542	folic acid binding	2/721	13/18639	0.153846153846154	3.97716846260536	0.0879330638138682	0.348245922328932
GO:0070700	BMP receptor binding	2/721	13/18639	0.153846153846154	3.97716846260536	0.0879330638138682	0.348245922328932
GO:0016248	channel inhibitor activity	4/721	44/18639	0.0909090909090909	2.35014500063044	0.0893797164423909	0.352422653867147
GO:0051019	mitogen-activated protein kinase binding	3/721	28/18639	0.107142857142857	2.76981375074302	0.0924073799040987	0.362769583116964
GO:0046915	transition metal ion transmembrane transporter activity	4/721	45/18639	0.0888888888888889	2.29791955617198	0.095257171839264	0.370719469625534
GO:0141110	transporter inhibitor activity	4/721	45/18639	0.0888888888888889	2.29791955617198	0.095257171839264	0.370719469625534
GO:0003697	single-stranded DNA binding	8/721	121/18639	0.0661157024793388	1.70919636409486	0.0973534328423729	0.375998060190742
GO:0032036	myosin heavy chain binding	2/721	14/18639	0.142857142857143	3.69308500099069	0.100047125511163	0.375998060190742
GO:0044548	S100 protein binding	2/721	14/18639	0.142857142857143	3.69308500099069	0.100047125511163	0.375998060190742
GO:0071933	Arp2/3 complex binding	2/721	14/18639	0.142857142857143	3.69308500099069	0.100047125511163	0.375998060190742
GO:0003785	actin monomer binding	3/721	29/18639	0.103448275862069	2.67430293175188	0.100247890504786	0.375998060190742
GO:0004629	phospholipase C activity	3/721	29/18639	0.103448275862069	2.67430293175188	0.100247890504786	0.375998060190742
GO:0043236	laminin binding	3/721	29/18639	0.103448275862069	2.67430293175188	0.100247890504786	0.375998060190742
GO:0051861	glycolipid binding	3/721	29/18639	0.103448275862069	2.67430293175188	0.100247890504786	0.375998060190742
GO:0008238	exopeptidase activity	7/721	102/18639	0.0686274509803922	1.77412906910337	0.100377680139909	0.375998060190742
GO:0004180	carboxypeptidase activity	4/721	46/18639	0.0869565217391304	2.24796478321172	0.101311617405224	0.377921759532351
GO:0140104	molecular carrier activity	14/721	249/18639	0.0562248995983936	1.45350333372324	0.104428314999015	0.387938244562455
GO:0031210	phosphatidylcholine binding	3/721	30/18639	0.1	2.58515950069348	0.108344274476679	0.400829229442528
GO:0015116	sulfate transmembrane transporter activity	2/721	15/18639	0.133333333333333	3.44687933425797	0.112589413348125	0.413134214693733
GO:0016846	carbon-sulfur lyase activity	2/721	15/18639	0.133333333333333	3.44687933425797	0.112589413348125	0.413134214693733
GO:0019887	protein kinase regulator activity	14/721	255/18639	0.0549019607843137	1.4193032552827	0.11996323037528	0.437283938507826
GO:0008081	phosphoric diester hydrolase activity	6/721	87/18639	0.0689655172413793	1.78286862116792	0.120587364344398	0.437283938507826
GO:0019209	kinase activator activity	9/721	148/18639	0.0608108108108108	1.57205645312441	0.120630052002159	0.437283938507826
GO:0032934	sterol binding	5/721	68/18639	0.0735294117647059	1.90085257403932	0.122614032125341	0.442690822813982
GO:0031369	translation initiation factor binding	3/721	32/18639	0.09375	2.42358703190014	0.125255444139254	0.449531460450228
GO:0005159	insulin-like growth factor receptor binding	2/721	16/18639	0.125	3.23144937586685	0.125508783729708	0.449531460450228
GO:0048020	CCR chemokine receptor binding	4/721	50/18639	0.08	2.06812760055479	0.12720889587025	0.452833612397987
GO:0035591	signaling adaptor activity	8/721	129/18639	0.062015503875969	1.60319969035255	0.127438157882859	0.452833612397987
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	6/721	89/18639	0.0674157303370786	1.74280415777089	0.130419608089501	0.459793049695926
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	6/721	89/18639	0.0674157303370786	1.74280415777089	0.130419608089501	0.459793049695926
GO:0097110	scaffold protein binding	5/721	70/18639	0.0714285714285714	1.84654250049534	0.134019958902753	0.465392791509807
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	3/721	33/18639	0.0909090909090909	2.35014500063044	0.134045237569662	0.465392791509807
GO:0140311	protein sequestering activity	3/721	33/18639	0.0909090909090909	2.35014500063044	0.134045237569662	0.465392791509807
GO:0005030	neurotrophin receptor activity	4/721	51/18639	0.0784313725490196	2.02757607897528	0.134078679645206	0.465392791509807
GO:0140793	histone H2AXY142 phosphatase activity	6/721	90/18639	0.0666666666666667	1.72343966712899	0.135475641393137	0.467195637900508
GO:0031072	heat shock protein binding	8/721	131/18639	0.0610687022900763	1.57872335920213	0.135637443261438	0.467195637900508
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/721	17/18639	0.117647058823529	3.04136411846292	0.138757399301812	0.468958278091463
GO:0046965	nuclear retinoid X receptor binding	2/721	17/18639	0.117647058823529	3.04136411846292	0.138757399301812	0.468958278091463
GO:0051787	misfolded protein binding	2/721	17/18639	0.117647058823529	3.04136411846292	0.138757399301812	0.468958278091463
GO:0070403	NAD+ binding	2/721	17/18639	0.117647058823529	3.04136411846292	0.138757399301812	0.468958278091463
GO:0070492	oligosaccharide binding	2/721	17/18639	0.117647058823529	3.04136411846292	0.138757399301812	0.468958278091463
GO:0072341	modified amino acid binding	6/721	91/18639	0.0659340659340659	1.70450076968801	0.140622731494291	0.473482530387145
GO:0005200	structural constituent of cytoskeleton	7/721	112/18639	0.0625	1.61572468793343	0.143467645449918	0.481259004699538
GO:0043021	ribonucleoprotein complex binding	10/721	177/18639	0.0564971751412429	1.46054209078728	0.149151151873562	0.49846425849194
GO:0034185	apolipoprotein binding	2/721	18/18639	0.111111111111111	2.87239944521498	0.15229055027239	0.501498918296259
GO:0098641	cadherin binding involved in cell-cell adhesion	2/721	18/18639	0.111111111111111	2.87239944521498	0.15229055027239	0.501498918296259
GO:1901611	phosphatidylglycerol binding	2/721	18/18639	0.111111111111111	2.87239944521498	0.15229055027239	0.501498918296259
GO:1990381	ubiquitin-specific protease binding	2/721	18/18639	0.111111111111111	2.87239944521498	0.15229055027239	0.501498918296259
GO:0005319	lipid transporter activity	10/721	178/18639	0.0561797752808989	1.45233679814241	0.152943494958711	0.501810956087159
GO:0016829	lyase activity	11/721	200/18639	0.055	1.42183772538141	0.153534716973983	0.501918947489494
GO:0015485	cholesterol binding	4/721	54/18639	0.0740740740740741	1.91493296347665	0.155553008956015	0.504845325095514
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	4/721	54/18639	0.0740740740740741	1.91493296347665	0.155553008956015	0.504845325095514
GO:0044325	transmembrane transporter binding	8/721	136/18639	0.0588235294117647	1.52068205923146	0.157260116464638	0.506033656167016
GO:0140789	histone phosphatase activity	8/721	136/18639	0.0588235294117647	1.52068205923146	0.157260116464638	0.506033656167016
GO:0001221	transcription coregulator binding	7/721	115/18639	0.0608695652173913	1.57357534824821	0.157886501868545	0.506033656167016
GO:0048029	monosaccharide binding	5/721	74/18639	0.0675675675675676	1.74672939236046	0.158170697867554	0.506033656167016
GO:0042393	histone binding	13/721	247/18639	0.0526315789473684	1.36061026352288	0.162619517415529	0.517738038801206
GO:0098632	cell-cell adhesion mediator activity	4/721	55/18639	0.0727272727272727	1.88011600050435	0.162980939911837	0.517738038801206
GO:0003725	double-stranded RNA binding	5/721	75/18639	0.0666666666666667	1.72343966712899	0.164469825662565	0.51838114456985
GO:0043395	heparan sulfate proteoglycan binding	2/721	19/18639	0.105263157894737	2.72122052704577	0.16606648457855	0.51838114456985
GO:0050145	nucleoside monophosphate kinase activity	2/721	19/18639	0.105263157894737	2.72122052704577	0.16606648457855	0.51838114456985
GO:0097001	ceramide binding	2/721	19/18639	0.105263157894737	2.72122052704577	0.16606648457855	0.51838114456985
GO:1990380	K48-linked deubiquitinase activity	2/721	19/18639	0.105263157894737	2.72122052704577	0.16606648457855	0.51838114456985
GO:0019208	phosphatase regulator activity	7/721	117/18639	0.0598290598290598	1.54667662434653	0.167851958800907	0.521009162187004
GO:0099106	ion channel regulator activity	9/721	160/18639	0.05625	1.45415221914008	0.168067471673227	0.521009162187004
GO:0170055	lipid transmembrane transporter activity	4/721	56/18639	0.0714285714285714	1.84654250049534	0.170534290531189	0.526060298199112
GO:0017022	myosin binding	5/721	76/18639	0.0657894736842105	1.70076282940361	0.170867193630857	0.526060298199112
GO:0004866	endopeptidase inhibitor activity	9/721	161/18639	0.0559006211180124	1.44512021777896	0.172371445641457	0.528880305910136
GO:0004725	protein tyrosine phosphatase activity	6/721	98/18639	0.0612244897959184	1.58275071471029	0.179046016709961	0.545635149227983
GO:0042626	ATPase-coupled transmembrane transporter activity	6/721	98/18639	0.0612244897959184	1.58275071471029	0.179046016709961	0.545635149227983
GO:0010851	cyclase regulator activity	2/721	20/18639	0.1	2.58515950069348	0.180046246484138	0.546829647260947
GO:0019199	transmembrane receptor protein kinase activity	5/721	78/18639	0.0641025641025641	1.65715352608556	0.183943410908464	0.556784937396327
GO:0008234	cysteine-type peptidase activity	10/721	187/18639	0.053475935828877	1.38243823566496	0.18916909277788	0.570681256400383
GO:0016835	carbon-oxygen lyase activity	5/721	79/18639	0.0632911392405063	1.63617689917309	0.190615495382551	0.571374655984495
GO:0016776	phosphotransferase activity, phosphate group as acceptor	3/721	39/18639	0.0769230769230769	1.98858423130268	0.190670074299609	0.571374655984495
GO:0140297	DNA-binding transcription factor binding	23/721	488/18639	0.0471311475409836	1.2184153384416	0.191693639083622	0.572533493475669
GO:0001786	phosphatidylserine binding	4/721	59/18639	0.0677966101694915	1.75265050894473	0.193888580128179	0.574276241338037
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/721	21/18639	0.0952380952380952	2.46205666732713	0.194193523211083	0.574276241338037
GO:0070182	DNA polymerase binding	2/721	21/18639	0.0952380952380952	2.46205666732713	0.194193523211083	0.574276241338037
GO:0061791	GTPase motor activity	3/721	40/18639	0.075	1.93886962552011	0.200639196229616	0.589459599380473
GO:1990606	membrane scission GTPase motor activity	3/721	40/18639	0.075	1.93886962552011	0.200639196229616	0.589459599380473
GO:0016247	channel regulator activity	9/721	168/18639	0.0535714285714286	1.38490687537151	0.203865580666681	0.596987482147708
GO:0031683	G-protein beta/gamma-subunit complex binding	2/721	22/18639	0.0909090909090909	2.35014500063044	0.208474499225818	0.606749531805039
GO:0030414	peptidase inhibitor activity	9/721	169/18639	0.0532544378698225	1.37671216013262	0.20854906043132	0.606749531805039
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	4/721	61/18639	0.0655737704918033	1.69518655783179	0.209977703171019	0.608935339195955
GO:0141108	transporter regulator activity	9/721	170/18639	0.0529411764705882	1.36861385330831	0.213275745130234	0.616510915987396
GO:0015179	L-amino acid transmembrane transporter activity	4/721	62/18639	0.0645161290322581	1.66784483915708	0.218160379409435	0.6286095547727
GO:0008307	structural constituent of muscle	3/721	42/18639	0.0714285714285714	1.84654250049534	0.220924518518537	0.634540390249728
GO:0016493	C-C chemokine receptor activity	2/721	23/18639	0.0869565217391304	2.24796478321172	0.222857717819317	0.636028851808146
GO:0017134	fibroblast growth factor binding	2/721	23/18639	0.0869565217391304	2.24796478321172	0.222857717819317	0.636028851808146
GO:0004860	protein kinase inhibitor activity	5/721	84/18639	0.0595238095238095	1.53878541707945	0.225176343477307	0.640612445525628
GO:0005507	copper ion binding	4/721	63/18639	0.0634920634920635	1.64137111155142	0.226427245811869	0.642139097744071
GO:0019888	protein phosphatase regulator activity	6/721	107/18639	0.0560747663551402	1.44962214992158	0.233742329413674	0.660799855795261
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/721	24/18639	0.0833333333333333	2.15429958391123	0.237313949635693	0.662562859386608
GO:0019957	C-C chemokine binding	2/721	24/18639	0.0833333333333333	2.15429958391123	0.237313949635693	0.662562859386608
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/721	24/18639	0.0833333333333333	2.15429958391123	0.237313949635693	0.662562859386608
GO:0070840	dynein complex binding	2/721	24/18639	0.0833333333333333	2.15429958391123	0.237313949635693	0.662562859386608
GO:0016298	lipase activity	7/721	130/18639	0.0538461538461538	1.39200896191187	0.238633504119253	0.66418427307495
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	5/721	86/18639	0.0581395348837209	1.50299970970551	0.239494413245813	0.664204261071493
GO:0003774	cytoskeletal motor activity	8/721	153/18639	0.0522875816993464	1.35171738598352	0.241286359672867	0.664204261071493
GO:0019205	nucleobase-containing compound kinase activity	3/721	44/18639	0.0681818181818182	1.76260875047283	0.241595988176172	0.664204261071493
GO:0030547	signaling receptor inhibitor activity	3/721	44/18639	0.0681818181818182	1.76260875047283	0.241595988176172	0.664204261071493
GO:0042578	phosphoric ester hydrolase activity	17/721	363/18639	0.046831955922865	1.21068075790053	0.242560686992624	0.664522313383024
GO:0120013	lipid transfer activity	4/721	65/18639	0.0615384615384615	1.59086738504214	0.243190034597347	0.664522313383024
GO:0004620	phospholipase activity	6/721	109/18639	0.055045871559633	1.42302357836338	0.246553758243807	0.669912037408685
GO:0005506	iron ion binding	8/721	154/18639	0.051948051948052	1.34294000036025	0.246652819112653	0.669912037408685
GO:0005537	D-mannose binding	2/721	25/18639	0.08	2.06812760055479	0.251816067820094	0.673757871935311
GO:0015645	fatty acid ligase activity	2/721	25/18639	0.08	2.06812760055479	0.251816067820094	0.673757871935311
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/721	25/18639	0.08	2.06812760055479	0.251816067820094	0.673757871935311
GO:0017056	structural constituent of nuclear pore	2/721	25/18639	0.08	2.06812760055479	0.251816067820094	0.673757871935311
GO:0120515	fatty acid-CoA ligase activity	2/721	25/18639	0.08	2.06812760055479	0.251816067820094	0.673757871935311
GO:0001637	G protein-coupled chemoattractant receptor activity	2/721	26/18639	0.0769230769230769	1.98858423130268	0.2663389294716	0.701639436408995
GO:0004950	chemokine receptor activity	2/721	26/18639	0.0769230769230769	1.98858423130268	0.2663389294716	0.701639436408995
GO:0008198	ferrous iron binding	2/721	26/18639	0.0769230769230769	1.98858423130268	0.2663389294716	0.701639436408995
GO:0050681	nuclear androgen receptor binding	2/721	26/18639	0.0769230769230769	1.98858423130268	0.2663389294716	0.701639436408995
GO:0019210	kinase inhibitor activity	5/721	90/18639	0.0555555555555556	1.43619972260749	0.268818342910312	0.701639436408995
GO:0061749	forked DNA-dependent helicase activity	3/721	47/18639	0.0638297872340425	1.65010180895329	0.273135301492564	0.701639436408995
GO:1990518	single-stranded 3'-5' DNA helicase activity	3/721	47/18639	0.0638297872340425	1.65010180895329	0.273135301492564	0.701639436408995
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	16/721	349/18639	0.0458452722063037	1.18517341006005	0.277983196805188	0.701639436408995
GO:0008320	protein transmembrane transporter activity	2/721	27/18639	0.0740740740740741	1.91493296347665	0.280859263101198	0.701639436408995
GO:0016405	CoA-ligase activity	2/721	27/18639	0.0740740740740741	1.91493296347665	0.280859263101198	0.701639436408995
GO:0009378	four-way junction helicase activity	3/721	48/18639	0.0625	1.61572468793343	0.28374873255128	0.701639436408995
GO:0036121	double-stranded DNA helicase activity	3/721	48/18639	0.0625	1.61572468793343	0.28374873255128	0.701639436408995
GO:0043138	3'-5' DNA helicase activity	3/721	48/18639	0.0625	1.61572468793343	0.28374873255128	0.701639436408995
GO:0043178	alcohol binding	5/721	92/18639	0.0543478260869565	1.40497798950733	0.283766544755313	0.701639436408995
GO:0008028	monocarboxylic acid transmembrane transporter activity	4/721	70/18639	0.0571428571428571	1.47723400039627	0.28616360764572	0.701639436408995
GO:0030295	protein kinase activator activity	7/721	139/18639	0.0503597122302158	1.30187888524132	0.292392274116436	0.701639436408995
GO:0001222	transcription corepressor binding	3/721	49/18639	0.0612244897959184	1.58275071471029	0.294395895810496	0.701639436408995
GO:0005004	GPI-linked ephrin receptor activity	3/721	49/18639	0.0612244897959184	1.58275071471029	0.294395895810496	0.701639436408995
GO:0005008	hepatocyte growth factor receptor activity	3/721	49/18639	0.0612244897959184	1.58275071471029	0.294395895810496	0.701639436408995
GO:0005009	insulin receptor activity	3/721	49/18639	0.0612244897959184	1.58275071471029	0.294395895810496	0.701639436408995
GO:0005011	macrophage colony-stimulating factor receptor activity	3/721	49/18639	0.0612244897959184	1.58275071471029	0.294395895810496	0.701639436408995
GO:0005018	platelet-derived growth factor alpha-receptor activity	3/721	49/18639	0.0612244897959184	1.58275071471029	0.294395895810496	0.701639436408995
GO:0005020	stem cell factor receptor activity	3/721	49/18639	0.0612244897959184	1.58275071471029	0.294395895810496	0.701639436408995
GO:0008288	boss receptor activity	3/721	49/18639	0.0612244897959184	1.58275071471029	0.294395895810496	0.701639436408995
GO:0036332	placental growth factor receptor activity	3/721	49/18639	0.0612244897959184	1.58275071471029	0.294395895810496	0.701639436408995
GO:0038062	protein tyrosine kinase collagen receptor activity	3/721	49/18639	0.0612244897959184	1.58275071471029	0.294395895810496	0.701639436408995
GO:0060175	brain-derived neurotrophic factor receptor activity	3/721	49/18639	0.0612244897959184	1.58275071471029	0.294395895810496	0.701639436408995
GO:0046625	sphingolipid binding	2/721	28/18639	0.0714285714285714	1.84654250049534	0.295355561808667	0.701639436408995
GO:0003924	GTPase activity	15/721	331/18639	0.0453172205438066	1.17152243233844	0.301465191874268	0.701639436408995
GO:0046943	carboxylic acid transmembrane transporter activity	9/721	188/18639	0.0478723404255319	1.23757635671496	0.304528498841068	0.701639436408995
GO:0140597	protein carrier chaperone	9/721	188/18639	0.0478723404255319	1.23757635671496	0.304528498841068	0.701639436408995
GO:0005006	epidermal growth factor receptor activity	3/721	50/18639	0.06	1.55109570041609	0.305067406444981	0.701639436408995
GO:0005007	fibroblast growth factor receptor activity	3/721	50/18639	0.06	1.55109570041609	0.305067406444981	0.701639436408995
GO:0005017	platelet-derived growth factor receptor activity	3/721	50/18639	0.06	1.55109570041609	0.305067406444981	0.701639436408995
GO:0005019	platelet-derived growth factor beta-receptor activity	3/721	50/18639	0.06	1.55109570041609	0.305067406444981	0.701639436408995
GO:0004867	serine-type endopeptidase inhibitor activity	5/721	95/18639	0.0526315789473684	1.36061026352288	0.306466526999213	0.701639436408995
GO:0004181	metallocarboxypeptidase activity	2/721	29/18639	0.0689655172413793	1.78286862116792	0.309807981905251	0.701639436408995
GO:0005342	organic acid transmembrane transporter activity	9/721	189/18639	0.0476190476190476	1.23102833366356	0.309869779445498	0.701639436408995
GO:0005010	insulin-like growth factor receptor activity	3/721	51/18639	0.0588235294117647	1.52068205923146	0.315754201869967	0.701639436408995
GO:0005272	sodium channel activity	3/721	51/18639	0.0588235294117647	1.52068205923146	0.315754201869967	0.701639436408995
GO:0030544	Hsp70 protein binding	3/721	51/18639	0.0588235294117647	1.52068205923146	0.315754201869967	0.701639436408995
GO:0016874	ligase activity	8/721	167/18639	0.0479041916167665	1.23839976081125	0.319418315232437	0.701639436408995
GO:0001965	G-protein alpha-subunit binding	2/721	30/18639	0.0666666666666667	1.72343966712899	0.324198246721578	0.701639436408995
GO:0016769	transferase activity, transferring nitrogenous groups	2/721	30/18639	0.0666666666666667	1.72343966712899	0.324198246721578	0.701639436408995
GO:0033612	receptor serine/threonine kinase binding	2/721	30/18639	0.0666666666666667	1.72343966712899	0.324198246721578	0.701639436408995
GO:0048019	receptor antagonist activity	2/721	30/18639	0.0666666666666667	1.72343966712899	0.324198246721578	0.701639436408995
GO:0001094	TFIID-class transcription factor complex binding	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0003796	lysozyme activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0004955	prostaglandin receptor activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0005522	profilin binding	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0008239	dipeptidyl-peptidase activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0015279	store-operated calcium channel activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0016783	sulfurtransferase activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0019531	oxalate transmembrane transporter activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0031996	thioesterase binding	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0032356	oxidized DNA binding	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0043208	glycosphingolipid binding	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0043422	protein kinase B binding	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0047429	nucleoside triphosphate diphosphatase activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0050815	phosphoserine residue binding	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0070513	death domain binding	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0140940	histone H2A methyltransferase activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:1990259	histone H2AQ104 methyltransferase activity	1/721	10/18639	0.1	2.58515950069348	0.32605099948662	0.701639436408995
GO:0004864	protein phosphatase inhibitor activity	3/721	53/18639	0.0566037735849057	1.46329783058122	0.337139023025742	0.701639436408995
GO:0005003	ephrin receptor activity	3/721	53/18639	0.0566037735849057	1.46329783058122	0.337139023025742	0.701639436408995
GO:0005005	transmembrane-ephrin receptor activity	3/721	53/18639	0.0566037735849057	1.46329783058122	0.337139023025742	0.701639436408995
GO:0016860	intramolecular oxidoreductase activity	3/721	53/18639	0.0566037735849057	1.46329783058122	0.337139023025742	0.701639436408995
GO:0017046	peptide hormone binding	3/721	53/18639	0.0566037735849057	1.46329783058122	0.337139023025742	0.701639436408995
GO:0038064	collagen receptor activity	3/721	53/18639	0.0566037735849057	1.46329783058122	0.337139023025742	0.701639436408995
GO:0005164	tumor necrosis factor receptor binding	2/721	31/18639	0.0645161290322581	1.66784483915708	0.338509555352222	0.701639436408995
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/721	31/18639	0.0645161290322581	1.66784483915708	0.338509555352222	0.701639436408995
GO:0016878	acid-thiol ligase activity	2/721	31/18639	0.0645161290322581	1.66784483915708	0.338509555352222	0.701639436408995
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3/721	54/18639	0.0555555555555556	1.43619972260749	0.347820553265137	0.701639436408995
GO:0051287	NAD binding	3/721	54/18639	0.0555555555555556	1.43619972260749	0.347820553265137	0.701639436408995
GO:0008514	organic anion transmembrane transporter activity	12/721	269/18639	0.0446096654275093	1.15323100402683	0.348197007764869	0.701639436408995
GO:0000099	sulfur amino acid transmembrane transporter activity	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0004954	prostanoid receptor activity	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0005536	D-glucose binding	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0008432	JUN kinase binding	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0008503	benzodiazepine receptor activity	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0008526	phosphatidylinositol transfer activity	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0015217	ADP transmembrane transporter activity	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0019107	myristoyltransferase activity	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0032794	GTPase activating protein binding	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0034713	type I transforming growth factor beta receptor binding	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0047676	arachidonate-CoA ligase activity	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0050998	nitric-oxide synthase binding	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0097493	structural molecule activity conferring elasticity	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/721	11/18639	0.0909090909090909	2.35014500063044	0.352134913243136	0.701639436408995
GO:0015106	bicarbonate transmembrane transporter activity	2/721	32/18639	0.0625	1.61572468793343	0.352726496099754	0.701639436408995
GO:0022884	macromolecule transmembrane transporter activity	2/721	32/18639	0.0625	1.61572468793343	0.352726496099754	0.701639436408995
GO:0140313	molecular sequestering activity	3/721	55/18639	0.0545454545454545	1.41008700037826	0.358484377112443	0.701639436408995
GO:0046332	SMAD binding	4/721	79/18639	0.0506329113924051	1.30894151933847	0.365519769731098	0.701639436408995
GO:0004721	phosphoprotein phosphatase activity	8/721	175/18639	0.0457142857142857	1.18178720031702	0.36607615730727	0.701639436408995
GO:0019239	deaminase activity	2/721	33/18639	0.0606060606060606	1.56676333375363	0.366834964392018	0.701639436408995
GO:0030296	protein tyrosine kinase activator activity	2/721	33/18639	0.0606060606060606	1.56676333375363	0.366834964392018	0.701639436408995
GO:0071889	14-3-3 protein binding	2/721	33/18639	0.0606060606060606	1.56676333375363	0.366834964392018	0.701639436408995
GO:0019212	phosphatase inhibitor activity	3/721	56/18639	0.0535714285714286	1.38490687537151	0.369123061258551	0.701639436408995
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	6/721	128/18639	0.046875	1.21179351595007	0.375253909262356	0.701639436408995
GO:0003995	acyl-CoA dehydrogenase activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0004000	adenosine deaminase activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0004032	aldose reductase (NADPH) activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0004126	cytidine deaminase activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0004300	enoyl-CoA hydratase activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0004859	phospholipase inhibitor activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0005095	GTPase inhibitor activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0008179	adenylate cyclase binding	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0010853	cyclase activator activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0015132	prostaglandin transmembrane transporter activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0016208	AMP binding	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0016273	arginine N-methyltransferase activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0016274	protein-arginine N-methyltransferase activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0016840	carbon-nitrogen lyase activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0017166	vinculin binding	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0034452	dynactin binding	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0035197	siRNA binding	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0035259	nuclear glucocorticoid receptor binding	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0036009	protein-glutamine N-methyltransferase activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0097677	STAT family protein binding	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/721	12/18639	0.0833333333333333	2.15429958391123	0.377210644805929	0.701639436408995
GO:0019001	guanyl nucleotide binding	17/721	400/18639	0.0425	1.09869278779473	0.380229178330568	0.701639436408995
GO:0032561	guanyl ribonucleotide binding	17/721	400/18639	0.0425	1.09869278779473	0.380229178330568	0.701639436408995
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/721	34/18639	0.0588235294117647	1.52068205923146	0.38082208495686	0.701639436408995
GO:0051427	hormone receptor binding	2/721	34/18639	0.0588235294117647	1.52068205923146	0.38082208495686	0.701639436408995
GO:0090482	vitamin transmembrane transporter activity	2/721	34/18639	0.0588235294117647	1.52068205923146	0.38082208495686	0.701639436408995
GO:0033192	calmodulin-dependent protein phosphatase activity	4/721	81/18639	0.0493827160493827	1.2766219756511	0.383209080396904	0.701639436408995
GO:0140791	histone H2AXS140 phosphatase activity	4/721	81/18639	0.0493827160493827	1.2766219756511	0.383209080396904	0.701639436408995
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	4/721	81/18639	0.0493827160493827	1.2766219756511	0.383209080396904	0.701639436408995
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	4/721	81/18639	0.0493827160493827	1.2766219756511	0.383209080396904	0.701639436408995
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	4/721	81/18639	0.0493827160493827	1.2766219756511	0.383209080396904	0.701639436408995
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	4/721	81/18639	0.0493827160493827	1.2766219756511	0.383209080396904	0.701639436408995
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	4/721	81/18639	0.0493827160493827	1.2766219756511	0.383209080396904	0.701639436408995
GO:1990439	MAP kinase serine/threonine phosphatase activity	4/721	81/18639	0.0493827160493827	1.2766219756511	0.383209080396904	0.701639436408995
GO:0017116	single-stranded DNA helicase activity	3/721	58/18639	0.0517241379310345	1.33715146587594	0.390296886302723	0.709131652731174
GO:0061980	regulatory RNA binding	3/721	58/18639	0.0517241379310345	1.33715146587594	0.390296886302723	0.709131652731174
GO:0003714	transcription corepressor activity	9/721	204/18639	0.0441176470588235	1.14051154442359	0.391831084731724	0.709131652731174
GO:0005525	GTP binding	16/721	378/18639	0.0423280423280423	1.09424740770094	0.392013239545972	0.709131652731174
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	4/721	82/18639	0.0487804878048781	1.26105341497243	0.392033850286311	0.709131652731174
GO:0033549	MAP kinase phosphatase activity	4/721	82/18639	0.0487804878048781	1.26105341497243	0.392033850286311	0.709131652731174
GO:0016853	isomerase activity	8/721	180/18639	0.0444444444444444	1.14895977808599	0.395559460484512	0.714072198746138
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	4/721	83/18639	0.0481927710843374	1.24586000033421	0.400839820926081	0.715841432122721
GO:0019855	calcium channel inhibitor activity	1/721	13/18639	0.0769230769230769	1.98858423130268	0.4013171098886	0.715841432122721
GO:0031432	titin binding	1/721	13/18639	0.0769230769230769	1.98858423130268	0.4013171098886	0.715841432122721
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/721	13/18639	0.0769230769230769	1.98858423130268	0.4013171098886	0.715841432122721
GO:0071714	icosanoid transmembrane transporter activity	1/721	13/18639	0.0769230769230769	1.98858423130268	0.4013171098886	0.715841432122721
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/721	13/18639	0.0769230769230769	1.98858423130268	0.4013171098886	0.715841432122721
GO:0005179	hormone activity	6/721	132/18639	0.0454545454545455	1.17507250031522	0.403034180481729	0.717480650006088
GO:0005496	steroid binding	5/721	108/18639	0.0462962962962963	1.19683310217291	0.406578006200933	0.719240375632558
GO:0044390	ubiquitin-like protein conjugating enzyme binding	2/721	36/18639	0.0555555555555556	1.43619972260749	0.408386489528842	0.719240375632558
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	2/721	36/18639	0.0555555555555556	1.43619972260749	0.408386489528842	0.719240375632558
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	2/721	36/18639	0.0555555555555556	1.43619972260749	0.408386489528842	0.719240375632558
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	2/721	36/18639	0.0555555555555556	1.43619972260749	0.408386489528842	0.719240375632558
GO:0017018	myosin phosphatase activity	4/721	84/18639	0.0476190476190476	1.23102833366356	0.40962299479852	0.719240375632558
GO:0051117	ATPase binding	4/721	84/18639	0.0476190476190476	1.23102833366356	0.40962299479852	0.719240375632558
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	3/721	60/18639	0.05	1.29257975034674	0.411288950970534	0.720757830258304
GO:0004518	nuclease activity	9/721	209/18639	0.0430622009569378	1.113226579246	0.419513811603001	0.724132941063114
GO:0016836	hydro-lyase activity	3/721	61/18639	0.0491803278688525	1.27138991837384	0.421701601718784	0.724132941063114
GO:0019213	deacetylase activity	2/721	37/18639	0.0540540540540541	1.39738351388837	0.421943524617675	0.724132941063114
GO:0005347	ATP transmembrane transporter activity	1/721	14/18639	0.0714285714285714	1.84654250049534	0.42449172407148	0.724132941063114
GO:0005545	1-phosphatidylinositol binding	1/721	14/18639	0.0714285714285714	1.84654250049534	0.42449172407148	0.724132941063114
GO:0008494	translation activator activity	1/721	14/18639	0.0714285714285714	1.84654250049534	0.42449172407148	0.724132941063114
GO:0016530	metallochaperone activity	1/721	14/18639	0.0714285714285714	1.84654250049534	0.42449172407148	0.724132941063114
GO:0019992	diacylglycerol binding	1/721	14/18639	0.0714285714285714	1.84654250049534	0.42449172407148	0.724132941063114
GO:0031404	chloride ion binding	1/721	14/18639	0.0714285714285714	1.84654250049534	0.42449172407148	0.724132941063114
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/721	14/18639	0.0714285714285714	1.84654250049534	0.42449172407148	0.724132941063114
GO:0046030	inositol trisphosphate phosphatase activity	1/721	14/18639	0.0714285714285714	1.84654250049534	0.42449172407148	0.724132941063114
GO:0061783	peptidoglycan muralytic activity	1/721	14/18639	0.0714285714285714	1.84654250049534	0.42449172407148	0.724132941063114
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/721	14/18639	0.0714285714285714	1.84654250049534	0.42449172407148	0.724132941063114
GO:1901612	cardiolipin binding	1/721	14/18639	0.0714285714285714	1.84654250049534	0.42449172407148	0.724132941063114
GO:1902936	phosphatidylinositol bisphosphate binding	5/721	111/18639	0.045045045045045	1.16448626157364	0.429609239758634	0.731474822998129
GO:0005501	retinoid binding	2/721	38/18639	0.0526315789473684	1.36061026352288	0.435338585131276	0.736966319332103
GO:0019840	isoprenoid binding	2/721	38/18639	0.0526315789473684	1.36061026352288	0.435338585131276	0.736966319332103
GO:0042162	telomeric DNA binding	2/721	38/18639	0.0526315789473684	1.36061026352288	0.435338585131276	0.736966319332103
GO:1901682	sulfur compound transmembrane transporter activity	3/721	63/18639	0.0476190476190476	1.23102833366356	0.442332350874715	0.736966319332103
GO:0000774	adenyl-nucleotide exchange factor activity	1/721	15/18639	0.0666666666666667	1.72343966712899	0.44677046055172	0.736966319332103
GO:0004467	long-chain fatty acid-CoA ligase activity	1/721	15/18639	0.0666666666666667	1.72343966712899	0.44677046055172	0.736966319332103
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/721	15/18639	0.0666666666666667	1.72343966712899	0.44677046055172	0.736966319332103
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/721	15/18639	0.0666666666666667	1.72343966712899	0.44677046055172	0.736966319332103
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/721	15/18639	0.0666666666666667	1.72343966712899	0.44677046055172	0.736966319332103
GO:0004953	icosanoid receptor activity	1/721	15/18639	0.0666666666666667	1.72343966712899	0.44677046055172	0.736966319332103
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/721	15/18639	0.0666666666666667	1.72343966712899	0.44677046055172	0.736966319332103
GO:0015929	hexosaminidase activity	1/721	15/18639	0.0666666666666667	1.72343966712899	0.44677046055172	0.736966319332103
GO:0050780	dopamine receptor binding	1/721	15/18639	0.0666666666666667	1.72343966712899	0.44677046055172	0.736966319332103
GO:0061578	K63-linked deubiquitinase activity	1/721	15/18639	0.0666666666666667	1.72343966712899	0.44677046055172	0.736966319332103
GO:0120283	protein serine/threonine kinase binding	1/721	15/18639	0.0666666666666667	1.72343966712899	0.44677046055172	0.736966319332103
GO:0141050	histone H3K deacetylase activity	1/721	15/18639	0.0666666666666667	1.72343966712899	0.44677046055172	0.736966319332103
GO:0141051	histone H4K deacetylase activity	1/721	15/18639	0.0666666666666667	1.72343966712899	0.44677046055172	0.736966319332103
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/721	39/18639	0.0512820512820513	1.32572282086845	0.448563910041096	0.738569514884515
GO:0140713	histone chaperone activity	7/721	164/18639	0.0426829268292683	1.10342173810088	0.450048666028572	0.73965950778736
GO:0071855	neuropeptide receptor binding	2/721	40/18639	0.05	1.29257975034674	0.461612579189068	0.755656960862111
GO:0000062	fatty-acyl-CoA binding	1/721	16/18639	0.0625	1.61572468793343	0.468187905673188	0.755656960862111
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/721	16/18639	0.0625	1.61572468793343	0.468187905673188	0.755656960862111
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	1/721	16/18639	0.0625	1.61572468793343	0.468187905673188	0.755656960862111
GO:0005149	interleukin-1 receptor binding	1/721	16/18639	0.0625	1.61572468793343	0.468187905673188	0.755656960862111
GO:0008142	oxysterol binding	1/721	16/18639	0.0625	1.61572468793343	0.468187905673188	0.755656960862111
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/721	16/18639	0.0625	1.61572468793343	0.468187905673188	0.755656960862111
GO:0043023	ribosomal large subunit binding	1/721	16/18639	0.0625	1.61572468793343	0.468187905673188	0.755656960862111
GO:0055102	lipase inhibitor activity	1/721	16/18639	0.0625	1.61572468793343	0.468187905673188	0.755656960862111
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/721	16/18639	0.0625	1.61572468793343	0.468187905673188	0.755656960862111
GO:0008235	metalloexopeptidase activity	3/721	66/18639	0.0454545454545455	1.17507250031522	0.47271748163487	0.758996682463745
GO:0015175	neutral L-amino acid transmembrane transporter activity	2/721	41/18639	0.0487804878048781	1.26105341497243	0.474478460005144	0.758996682463745
GO:0016877	ligase activity, forming carbon-sulfur bonds	2/721	41/18639	0.0487804878048781	1.26105341497243	0.474478460005144	0.758996682463745
GO:0017080	sodium channel regulator activity	2/721	41/18639	0.0487804878048781	1.26105341497243	0.474478460005144	0.758996682463745
GO:0140318	protein transporter activity	2/721	41/18639	0.0487804878048781	1.26105341497243	0.474478460005144	0.758996682463745
GO:0008236	serine-type peptidase activity	8/721	194/18639	0.0412371134020619	1.06604515492515	0.4778185873378	0.76154385403282
GO:0016500	protein-hormone receptor activity	3/721	67/18639	0.0447761194029851	1.15753410478813	0.482678327240492	0.76154385403282
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	3/721	67/18639	0.0447761194029851	1.15753410478813	0.482678327240492	0.76154385403282
GO:0016859	cis-trans isomerase activity	2/721	42/18639	0.0476190476190476	1.23102833366356	0.487156157079475	0.76154385403282
GO:0035198	miRNA binding	2/721	42/18639	0.0476190476190476	1.23102833366356	0.487156157079475	0.76154385403282
GO:0016791	phosphatase activity	11/721	273/18639	0.0402930402930403	1.04163935925378	0.488544561323203	0.76154385403282
GO:0004550	nucleoside diphosphate kinase activity	1/721	17/18639	0.0588235294117647	1.52068205923146	0.488777312321398	0.76154385403282
GO:0005092	GDP-dissociation inhibitor activity	1/721	17/18639	0.0588235294117647	1.52068205923146	0.488777312321398	0.76154385403282
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/721	17/18639	0.0588235294117647	1.52068205923146	0.488777312321398	0.76154385403282
GO:0016018	cyclosporin A binding	1/721	17/18639	0.0588235294117647	1.52068205923146	0.488777312321398	0.76154385403282
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/721	17/18639	0.0588235294117647	1.52068205923146	0.488777312321398	0.76154385403282
GO:0032183	SUMO binding	1/721	17/18639	0.0588235294117647	1.52068205923146	0.488777312321398	0.76154385403282
GO:0032977	membrane insertase activity	1/721	17/18639	0.0588235294117647	1.52068205923146	0.488777312321398	0.76154385403282
GO:1901567	fatty acid derivative binding	1/721	17/18639	0.0588235294117647	1.52068205923146	0.488777312321398	0.76154385403282
GO:1990226	histone methyltransferase binding	1/721	17/18639	0.0588235294117647	1.52068205923146	0.488777312321398	0.76154385403282
GO:0042562	hormone binding	4/721	94/18639	0.0425531914893617	1.10006787263552	0.495413523668384	0.770548023837158
GO:0005245	voltage-gated calcium channel activity	2/721	43/18639	0.0465116279069767	1.20239976776441	0.499640964448596	0.77100339879873
GO:0017171	serine hydrolase activity	8/721	198/18639	0.0404040404040404	1.04450888916908	0.500902774416151	0.77100339879873
GO:0002039	p53 binding	3/721	69/18639	0.0434782608695652	1.12398239160586	0.502325041578028	0.77100339879873
GO:0004540	RNA nuclease activity	5/721	121/18639	0.0413223140495868	1.06824772755929	0.504677395928319	0.77100339879873
GO:0015085	calcium ion transmembrane transporter activity	6/721	147/18639	0.0408163265306122	1.0551671431402	0.505430681545596	0.77100339879873
GO:0000400	four-way junction DNA binding	1/721	18/18639	0.0555555555555556	1.43619972260749	0.508570651265458	0.77100339879873
GO:0008409	5'-3' exonuclease activity	1/721	18/18639	0.0555555555555556	1.43619972260749	0.508570651265458	0.77100339879873
GO:0008525	phosphatidylcholine transporter activity	1/721	18/18639	0.0555555555555556	1.43619972260749	0.508570651265458	0.77100339879873
GO:0015172	acidic amino acid transmembrane transporter activity	1/721	18/18639	0.0555555555555556	1.43619972260749	0.508570651265458	0.77100339879873
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/721	18/18639	0.0555555555555556	1.43619972260749	0.508570651265458	0.77100339879873
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/721	18/18639	0.0555555555555556	1.43619972260749	0.508570651265458	0.77100339879873
GO:0017075	syntaxin-1 binding	1/721	18/18639	0.0555555555555556	1.43619972260749	0.508570651265458	0.77100339879873
GO:0050811	GABA receptor binding	1/721	18/18639	0.0555555555555556	1.43619972260749	0.508570651265458	0.77100339879873
GO:0070628	proteasome binding	1/721	18/18639	0.0555555555555556	1.43619972260749	0.508570651265458	0.77100339879873
GO:0099602	neurotransmitter receptor regulator activity	1/721	18/18639	0.0555555555555556	1.43619972260749	0.508570651265458	0.77100339879873
GO:0001223	transcription coactivator binding	2/721	44/18639	0.0454545454545455	1.17507250031522	0.511928820461568	0.774787894940993
GO:0004252	serine-type endopeptidase activity	7/721	176/18639	0.0397727272727273	1.02818843777582	0.524328721899121	0.790518659687886
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/721	19/18639	0.0526315789473684	1.36061026352288	0.527598660525842	0.790518659687886
GO:0008381	mechanosensitive monoatomic ion channel activity	1/721	19/18639	0.0526315789473684	1.36061026352288	0.527598660525842	0.790518659687886
GO:0030506	ankyrin binding	1/721	19/18639	0.0526315789473684	1.36061026352288	0.527598660525842	0.790518659687886
GO:0046624	sphingolipid transporter activity	1/721	19/18639	0.0526315789473684	1.36061026352288	0.527598660525842	0.790518659687886
GO:0120227	acyl-CoA binding	1/721	19/18639	0.0526315789473684	1.36061026352288	0.527598660525842	0.790518659687886
GO:0003713	transcription coactivator activity	10/721	256/18639	0.0390625	1.00982792995839	0.532860166836059	0.797073693819662
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/721	46/18639	0.0434782608695652	1.12398239160586	0.535900399618335	0.798962618999807
GO:0030276	clathrin binding	2/721	46/18639	0.0434782608695652	1.12398239160586	0.535900399618335	0.798962618999807
GO:0004521	RNA endonuclease activity	3/721	73/18639	0.0410958904109589	1.06239431535349	0.54042564609519	0.80304571213153
GO:0043539	protein serine/threonine kinase activator activity	3/721	73/18639	0.0410958904109589	1.06239431535349	0.54042564609519	0.80304571213153
GO:0001972	retinoic acid binding	1/721	20/18639	0.05	1.29257975034674	0.545890892843826	0.803397356470605
GO:0016408	C-acyltransferase activity	1/721	20/18639	0.05	1.29257975034674	0.545890892843826	0.803397356470605
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/721	20/18639	0.05	1.29257975034674	0.545890892843826	0.803397356470605
GO:0052745	inositol phosphate phosphatase activity	1/721	20/18639	0.05	1.29257975034674	0.545890892843826	0.803397356470605
GO:0140939	histone H4 methyltransferase activity	1/721	20/18639	0.05	1.29257975034674	0.545890892843826	0.803397356470605
GO:0043495	protein-membrane adaptor activity	2/721	47/18639	0.0425531914893617	1.10006787263552	0.547578848423925	0.803397356470605
GO:0140359	ABC-type transporter activity	2/721	47/18639	0.0425531914893617	1.10006787263552	0.547578848423925	0.803397356470605
GO:0004519	endonuclease activity	5/721	127/18639	0.0393700787401575	1.01777933098169	0.547811545624561	0.803397356470605
GO:0003678	DNA helicase activity	3/721	74/18639	0.0405405405405405	1.04803763541628	0.549685678528736	0.804832939735071
GO:0019003	GDP binding	3/721	75/18639	0.04	1.03406380027739	0.558834854931668	0.813105472602875
GO:0044183	protein folding chaperone	3/721	75/18639	0.04	1.03406380027739	0.558834854931668	0.813105472602875
GO:0015171	amino acid transmembrane transporter activity	4/721	102/18639	0.0392156862745098	1.01378803948764	0.560031359986835	0.813105472602875
GO:0005261	monoatomic cation channel activity	13/721	341/18639	0.0381231671554252	0.985544677683732	0.561421761244338	0.813105472602875
GO:0005248	voltage-gated sodium channel activity	1/721	21/18639	0.0476190476190476	1.23102833366356	0.563475761325463	0.813105472602875
GO:0008373	sialyltransferase activity	1/721	21/18639	0.0476190476190476	1.23102833366356	0.563475761325463	0.813105472602875
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/721	21/18639	0.0476190476190476	1.23102833366356	0.563475761325463	0.813105472602875
GO:0015125	bile acid transmembrane transporter activity	1/721	21/18639	0.0476190476190476	1.23102833366356	0.563475761325463	0.813105472602875
GO:0035613	RNA stem-loop binding	1/721	21/18639	0.0476190476190476	1.23102833366356	0.563475761325463	0.813105472602875
GO:0004722	protein serine/threonine phosphatase activity	4/721	103/18639	0.0388349514563107	1.00394543716252	0.567791220123653	0.817719485846103
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	5/721	130/18639	0.0384615384615385	0.994292115651339	0.568692439252988	0.817719485846103
GO:0035254	glutamate receptor binding	2/721	49/18639	0.0408163265306122	1.0551671431402	0.570311588015024	0.817719485846103
GO:0060590	ATPase regulator activity	2/721	49/18639	0.0408163265306122	1.0551671431402	0.570311588015024	0.817719485846103
GO:0005262	calcium channel activity	5/721	131/18639	0.0381679389312977	0.986702099501329	0.575541663216889	0.823904387312076
GO:0051540	metal cluster binding	3/721	77/18639	0.038961038961039	1.00720500027019	0.576792679471847	0.824268790543218
GO:0004407	histone deacetylase activity	1/721	22/18639	0.0454545454545455	1.17507250031522	0.580380583330208	0.824268790543218
GO:0008093	cytoskeletal anchor activity	1/721	22/18639	0.0454545454545455	1.17507250031522	0.580380583330208	0.824268790543218
GO:0033558	protein lysine deacetylase activity	1/721	22/18639	0.0454545454545455	1.17507250031522	0.580380583330208	0.824268790543218
GO:0140517	protein-RNA adaptor activity	1/721	22/18639	0.0454545454545455	1.17507250031522	0.580380583330208	0.824268790543218
GO:0032813	tumor necrosis factor receptor superfamily binding	2/721	50/18639	0.04	1.03406380027739	0.581363428913776	0.824362338475528
GO:0004497	monooxygenase activity	4/721	106/18639	0.0377358490566038	0.975531887054144	0.590606835067059	0.836150464134308
GO:0005048	signal sequence binding	2/721	51/18639	0.0392156862745098	1.01378803948764	0.592204621854339	0.836773523840529
GO:0000295	adenine nucleotide transmembrane transporter activity	1/721	23/18639	0.0434782608695652	1.12398239160586	0.596631622671612	0.836773523840529
GO:0008171	O-methyltransferase activity	1/721	23/18639	0.0434782608695652	1.12398239160586	0.596631622671612	0.836773523840529
GO:0016849	phosphorus-oxygen lyase activity	1/721	23/18639	0.0434782608695652	1.12398239160586	0.596631622671612	0.836773523840529
GO:0031681	G-protein beta-subunit binding	1/721	23/18639	0.0434782608695652	1.12398239160586	0.596631622671612	0.836773523840529
GO:0140103	catalytic activity, acting on a glycoprotein	1/721	23/18639	0.0434782608695652	1.12398239160586	0.596631622671612	0.836773523840529
GO:0004175	endopeptidase activity	15/721	405/18639	0.037037037037037	0.957466481738326	0.605769769821724	0.840420216187453
GO:0099094	ligand-gated monoatomic cation channel activity	5/721	136/18639	0.0367647058823529	0.950426287019662	0.608902111460515	0.840420216187453
GO:0015101	organic cation transmembrane transporter activity	3/721	81/18639	0.037037037037037	0.957466481738326	0.611301113276586	0.840420216187453
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/721	24/18639	0.0416666666666667	1.07714979195562	0.612254130194913	0.840420216187453
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/721	24/18639	0.0416666666666667	1.07714979195562	0.612254130194913	0.840420216187453
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/721	24/18639	0.0416666666666667	1.07714979195562	0.612254130194913	0.840420216187453
GO:0004622	lysophospholipase activity	1/721	24/18639	0.0416666666666667	1.07714979195562	0.612254130194913	0.840420216187453
GO:0005315	phosphate transmembrane transporter activity	1/721	24/18639	0.0416666666666667	1.07714979195562	0.612254130194913	0.840420216187453
GO:0015149	hexose transmembrane transporter activity	1/721	24/18639	0.0416666666666667	1.07714979195562	0.612254130194913	0.840420216187453
GO:0030215	semaphorin receptor binding	1/721	24/18639	0.0416666666666667	1.07714979195562	0.612254130194913	0.840420216187453
GO:0050431	transforming growth factor beta binding	1/721	24/18639	0.0416666666666667	1.07714979195562	0.612254130194913	0.840420216187453
GO:0055056	D-glucose transmembrane transporter activity	1/721	24/18639	0.0416666666666667	1.07714979195562	0.612254130194913	0.840420216187453
GO:0070300	phosphatidic acid binding	1/721	24/18639	0.0416666666666667	1.07714979195562	0.612254130194913	0.840420216187453
GO:0005246	calcium channel regulator activity	2/721	53/18639	0.0377358490566038	0.975531887054144	0.6132543513003	0.840420216187453
GO:0051018	protein kinase A binding	2/721	53/18639	0.0377358490566038	0.975531887054144	0.6132543513003	0.840420216187453
GO:0016922	nuclear receptor binding	5/721	137/18639	0.0364963503649635	0.943488868866234	0.615389967990381	0.842063289533261
GO:0003925	G protein activity	2/721	54/18639	0.037037037037037	0.957466481738326	0.623463343532422	0.846723531729254
GO:0140463	chromatin-protein adaptor activity	2/721	54/18639	0.037037037037037	0.957466481738326	0.623463343532422	0.846723531729254
GO:0008483	transaminase activity	1/721	25/18639	0.04	1.03406380027739	0.627272382793863	0.846723531729254
GO:0015662	P-type ion transporter activity	1/721	25/18639	0.04	1.03406380027739	0.627272382793863	0.846723531729254
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/721	25/18639	0.04	1.03406380027739	0.627272382793863	0.846723531729254
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/721	25/18639	0.04	1.03406380027739	0.627272382793863	0.846723531729254
GO:0019707	protein-cysteine S-acyltransferase activity	1/721	25/18639	0.04	1.03406380027739	0.627272382793863	0.846723531729254
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	1/721	25/18639	0.04	1.03406380027739	0.627272382793863	0.846723531729254
GO:0140358	P-type transmembrane transporter activity	1/721	25/18639	0.04	1.03406380027739	0.627272382793863	0.846723531729254
GO:0004527	exonuclease activity	3/721	84/18639	0.0357142857142857	0.923271250247672	0.63591408914618	0.849627450829384
GO:0003712	transcription coregulator activity	18/721	495/18639	0.0363636363636364	0.940058000252175	0.640368694351974	0.849627450829384
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/721	26/18639	0.0384615384615385	0.994292115651339	0.641709720926754	0.849627450829384
GO:0004529	DNA exonuclease activity	1/721	26/18639	0.0384615384615385	0.994292115651339	0.641709720926754	0.849627450829384
GO:0005160	transforming growth factor beta receptor binding	1/721	26/18639	0.0384615384615385	0.994292115651339	0.641709720926754	0.849627450829384
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	1/721	26/18639	0.0384615384615385	0.994292115651339	0.641709720926754	0.849627450829384
GO:0015145	monosaccharide transmembrane transporter activity	1/721	26/18639	0.0384615384615385	0.994292115651339	0.641709720926754	0.849627450829384
GO:0015216	purine nucleotide transmembrane transporter activity	1/721	26/18639	0.0384615384615385	0.994292115651339	0.641709720926754	0.849627450829384
GO:0030507	spectrin binding	1/721	26/18639	0.0384615384615385	0.994292115651339	0.641709720926754	0.849627450829384
GO:0051139	metal cation:proton antiporter activity	1/721	26/18639	0.0384615384615385	0.994292115651339	0.641709720926754	0.849627450829384
GO:0052742	phosphatidylinositol kinase activity	1/721	26/18639	0.0384615384615385	0.994292115651339	0.641709720926754	0.849627450829384
GO:0070006	metalloaminopeptidase activity	1/721	26/18639	0.0384615384615385	0.994292115651339	0.641709720926754	0.849627450829384
GO:0120014	phospholipid transfer activity	1/721	26/18639	0.0384615384615385	0.994292115651339	0.641709720926754	0.849627450829384
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/721	27/18639	0.037037037037037	0.957466481738326	0.655588584689275	0.860400200927969
GO:0005104	fibroblast growth factor receptor binding	1/721	27/18639	0.037037037037037	0.957466481738326	0.655588584689275	0.860400200927969
GO:0008395	steroid hydroxylase activity	1/721	27/18639	0.037037037037037	0.957466481738326	0.655588584689275	0.860400200927969
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/721	27/18639	0.037037037037037	0.957466481738326	0.655588584689275	0.860400200927969
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/721	27/18639	0.037037037037037	0.957466481738326	0.655588584689275	0.860400200927969
GO:0035255	ionotropic glutamate receptor binding	1/721	27/18639	0.037037037037037	0.957466481738326	0.655588584689275	0.860400200927969
GO:0140030	modification-dependent protein binding	6/721	173/18639	0.0346820809248555	0.896587110067103	0.663975638228106	0.867775704330738
GO:0005216	monoatomic ion channel activity	16/721	448/18639	0.0357142857142857	0.923271250247672	0.664302163292737	0.867775704330738
GO:0005242	inward rectifier potassium channel activity	1/721	28/18639	0.0357142857142857	0.923271250247672	0.668930548499668	0.867775704330738
GO:0019789	SUMO transferase activity	1/721	28/18639	0.0357142857142857	0.923271250247672	0.668930548499668	0.867775704330738
GO:0046875	ephrin receptor binding	1/721	28/18639	0.0357142857142857	0.923271250247672	0.668930548499668	0.867775704330738
GO:0046966	nuclear thyroid hormone receptor binding	1/721	28/18639	0.0357142857142857	0.923271250247672	0.668930548499668	0.867775704330738
GO:0051119	sugar transmembrane transporter activity	1/721	28/18639	0.0357142857142857	0.923271250247672	0.668930548499668	0.867775704330738
GO:0051959	dynein light intermediate chain binding	1/721	28/18639	0.0357142857142857	0.923271250247672	0.668930548499668	0.867775704330738
GO:0031593	polyubiquitin modification-dependent protein binding	2/721	59/18639	0.0338983050847458	0.876325254472367	0.671383643103162	0.869703018947755
GO:0016417	S-acyltransferase activity	1/721	29/18639	0.0344827586206897	0.891434310583959	0.681756354449469	0.881869011007299
GO:0032182	ubiquitin-like protein binding	4/721	120/18639	0.0333333333333333	0.861719833564494	0.687123932830285	0.88513068774603
GO:0008509	monoatomic anion transmembrane transporter activity	5/721	149/18639	0.0335570469798658	0.867503188152175	0.688107284273687	0.88513068774603
GO:0019905	syntaxin binding	2/721	61/18639	0.0327868852459016	0.847593278915896	0.689120250128518	0.88513068774603
GO:0015108	chloride transmembrane transporter activity	4/721	121/18639	0.0330578512396694	0.854598182047432	0.693361421271378	0.88513068774603
GO:0051082	unfolded protein binding	4/721	121/18639	0.0330578512396694	0.854598182047432	0.693361421271378	0.88513068774603
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/721	30/18639	0.0333333333333333	0.861719833564494	0.69408594437112	0.88513068774603
GO:0015215	nucleotide transmembrane transporter activity	1/721	30/18639	0.0333333333333333	0.861719833564494	0.69408594437112	0.88513068774603
GO:0031624	ubiquitin conjugating enzyme binding	1/721	30/18639	0.0333333333333333	0.861719833564494	0.69408594437112	0.88513068774603
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/721	30/18639	0.0333333333333333	0.861719833564494	0.69408594437112	0.88513068774603
GO:0052689	carboxylic ester hydrolase activity	3/721	92/18639	0.0326086956521739	0.842986793704396	0.696115048284527	0.88513068774603
GO:0000510	H3-H4 histone complex chaperone activity	5/721	151/18639	0.033112582781457	0.856013079699828	0.699271360640464	0.88513068774603
GO:0140584	chromatin extrusion motor activity	5/721	151/18639	0.033112582781457	0.856013079699828	0.699271360640464	0.88513068774603
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	5/721	151/18639	0.033112582781457	0.856013079699828	0.699271360640464	0.88513068774603
GO:0140849	ATP-dependent H2AZ histone chaperone activity	5/721	151/18639	0.033112582781457	0.856013079699828	0.699271360640464	0.88513068774603
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/721	122/18639	0.0327868852459016	0.847593278915896	0.699509840006665	0.88513068774603
GO:0015616	DNA translocase activity	5/721	152/18639	0.0328947368421053	0.850381414701803	0.704748871044018	0.88513068774603
GO:0140674	ATP-dependent histone chaperone activity	5/721	152/18639	0.0328947368421053	0.850381414701803	0.704748871044018	0.88513068774603
GO:0005184	neuropeptide hormone activity	1/721	31/18639	0.032258064516129	0.833922419578542	0.70593849067175	0.88513068774603
GO:0005452	solute:inorganic anion antiporter activity	1/721	31/18639	0.032258064516129	0.833922419578542	0.70593849067175	0.88513068774603
GO:0017147	Wnt-protein binding	1/721	31/18639	0.032258064516129	0.833922419578542	0.70593849067175	0.88513068774603
GO:0047499	calcium-independent phospholipase A2 activity	1/721	31/18639	0.032258064516129	0.833922419578542	0.70593849067175	0.88513068774603
GO:0070273	phosphatidylinositol-4-phosphate binding	1/721	31/18639	0.032258064516129	0.833922419578542	0.70593849067175	0.88513068774603
GO:0061775	cohesin loader activity	5/721	153/18639	0.0326797385620915	0.8448233662397	0.710156545129826	0.889179295364503
GO:0004536	DNA nuclease activity	2/721	64/18639	0.03125	0.807862343966713	0.71423968469519	0.893047950682859
GO:0043425	bHLH transcription factor binding	1/721	32/18639	0.03125	0.807862343966713	0.717332425980524	0.893188159219517
GO:0047498	calcium-dependent phospholipase A2 activity	1/721	32/18639	0.03125	0.807862343966713	0.717332425980524	0.893188159219517
GO:0160041	neuropeptide activity	1/721	32/18639	0.03125	0.807862343966713	0.717332425980524	0.893188159219517
GO:0008237	metallopeptidase activity	6/721	184/18639	0.0326086956521739	0.842986793704396	0.720498640074347	0.895889733647079
GO:0160215	deacylase activity	2/721	65/18639	0.0307692307692308	0.795433692521071	0.722226021857537	0.896797228798241
GO:0042923	neuropeptide binding	1/721	33/18639	0.0303030303030303	0.783381666876813	0.728285471655165	0.903073984852405
GO:0015276	ligand-gated monoatomic ion channel activity	6/721	186/18639	0.032258064516129	0.833922419578542	0.730030504790945	0.903732484019029
GO:0140996	histone H3 kinase activity	12/721	357/18639	0.0336134453781513	0.868961176703691	0.730827047699481	0.903732484019029
GO:0140658	ATP-dependent chromatin remodeler activity	5/721	158/18639	0.0316455696202532	0.818088449586545	0.736146427131217	0.906765196576335
GO:0015035	protein-disulfide reductase activity	1/721	34/18639	0.0294117647058824	0.76034102961573	0.738814665191477	0.906765196576335
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/721	34/18639	0.0294117647058824	0.76034102961573	0.738814665191477	0.906765196576335
GO:0030332	cyclin binding	1/721	34/18639	0.0294117647058824	0.76034102961573	0.738814665191477	0.906765196576335
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/721	34/18639	0.0294117647058824	0.76034102961573	0.738814665191477	0.906765196576335
GO:0022834	ligand-gated channel activity	6/721	188/18639	0.0319148936170213	0.825050904476643	0.739331356051673	0.906765196576335
GO:0035173	histone kinase activity	12/721	360/18639	0.0333333333333333	0.861719833564494	0.741031687780378	0.907612380537547
GO:0003689	DNA clamp loader activity	5/721	160/18639	0.03125	0.807862343966713	0.746054084010812	0.911087701669358
GO:0043130	ubiquitin binding	3/721	100/18639	0.03	0.775547850208044	0.74847115571828	0.911087701669358
GO:0004623	phospholipase A2 activity	1/721	35/18639	0.0285714285714286	0.738617000198137	0.748936386578037	0.911087701669358
GO:0043015	gamma-tubulin binding	1/721	35/18639	0.0285714285714286	0.738617000198137	0.748936386578037	0.911087701669358
GO:0140566	histone reader activity	1/721	35/18639	0.0285714285714286	0.738617000198137	0.748936386578037	0.911087701669358
GO:0001217	DNA-binding transcription repressor activity	9/721	278/18639	0.0323741007194245	0.836922140512278	0.752511316470701	0.91419955879346
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	4/721	132/18639	0.0303030303030303	0.783381666876813	0.756121136964913	0.914264180816743
GO:0004033	aldo-keto reductase (NADPH) activity	1/721	36/18639	0.0277777777777778	0.718099861303745	0.758666383636586	0.914264180816743
GO:0004190	aspartic-type endopeptidase activity	1/721	36/18639	0.0277777777777778	0.718099861303745	0.758666383636586	0.914264180816743
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/721	36/18639	0.0277777777777778	0.718099861303745	0.758666383636586	0.914264180816743
GO:0005484	SNAP receptor activity	1/721	36/18639	0.0277777777777778	0.718099861303745	0.758666383636586	0.914264180816743
GO:0016409	palmitoyltransferase activity	1/721	36/18639	0.0277777777777778	0.718099861303745	0.758666383636586	0.914264180816743
GO:0005253	monoatomic anion channel activity	3/721	103/18639	0.029126213592233	0.752959077871888	0.766149348551629	0.919373897406142
GO:0022829	wide pore channel activity	1/721	37/18639	0.027027027027027	0.698691756944184	0.768019796387111	0.919373897406142
GO:0030280	structural constituent of skin epidermis	1/721	37/18639	0.027027027027027	0.698691756944184	0.768019796387111	0.919373897406142
GO:0042805	actinin binding	1/721	37/18639	0.027027027027027	0.698691756944184	0.768019796387111	0.919373897406142
GO:0070001	aspartic-type peptidase activity	1/721	37/18639	0.027027027027027	0.698691756944184	0.768019796387111	0.919373897406142
GO:0046982	protein heterodimerization activity	12/721	369/18639	0.032520325203252	0.840702276648287	0.770094742091264	0.920631879175594
GO:0015297	antiporter activity	4/721	135/18639	0.0296296296296296	0.765973185390661	0.771404314646993	0.920972747500195
GO:0005109	frizzled binding	1/721	38/18639	0.0263157894736842	0.680305131761442	0.777011180475107	0.92643640748955
GO:0008013	beta-catenin binding	3/721	106/18639	0.0283018867924528	0.731648915290608	0.78280343660231	0.930888747256484
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/721	39/18639	0.0256410256410256	0.662861410434226	0.785654529697054	0.930888747256484
GO:0003684	damaged DNA binding	2/721	74/18639	0.027027027027027	0.698691756944184	0.785922757694851	0.930888747256484
GO:0031491	nucleosome binding	2/721	74/18639	0.027027027027027	0.698691756944184	0.785922757694851	0.930888747256484
GO:0035064	methylated histone binding	2/721	74/18639	0.027027027027027	0.698691756944184	0.785922757694851	0.930888747256484
GO:0004177	aminopeptidase activity	1/721	40/18639	0.025	0.64628987517337	0.793963297658797	0.933036607314064
GO:0015036	disulfide oxidoreductase activity	1/721	40/18639	0.025	0.64628987517337	0.793963297658797	0.933036607314064
GO:0015144	carbohydrate transmembrane transporter activity	1/721	40/18639	0.025	0.64628987517337	0.793963297658797	0.933036607314064
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/721	40/18639	0.025	0.64628987517337	0.793963297658797	0.933036607314064
GO:0030331	nuclear estrogen receptor binding	1/721	40/18639	0.025	0.64628987517337	0.793963297658797	0.933036607314064
GO:0140662	ATP-dependent protein folding chaperone	1/721	40/18639	0.025	0.64628987517337	0.793963297658797	0.933036607314064
GO:0051536	iron-sulfur cluster binding	2/721	76/18639	0.0263157894736842	0.680305131761442	0.798205782126555	0.935576268750682
GO:0140034	methylation-dependent protein binding	2/721	76/18639	0.0263157894736842	0.680305131761442	0.798205782126555	0.935576268750682
GO:0001727	lipid kinase activity	1/721	41/18639	0.024390243902439	0.630526707486215	0.801950418600139	0.936303151066915
GO:0008227	G protein-coupled amine receptor activity	1/721	41/18639	0.024390243902439	0.630526707486215	0.801950418600139	0.936303151066915
GO:0140828	metal cation:monoatomic cation antiporter activity	1/721	41/18639	0.024390243902439	0.630526707486215	0.801950418600139	0.936303151066915
GO:0004222	metalloendopeptidase activity	3/721	110/18639	0.0272727272727273	0.705043500189131	0.80347268427656	0.936863739513135
GO:0004520	DNA endonuclease activity	1/721	42/18639	0.0238095238095238	0.615514166831781	0.809628327417716	0.93916885980455
GO:0019894	kinesin binding	1/721	42/18639	0.0238095238095238	0.615514166831781	0.809628327417716	0.93916885980455
GO:0031492	nucleosomal DNA binding	1/721	42/18639	0.0238095238095238	0.615514166831781	0.809628327417716	0.93916885980455
GO:0051879	Hsp90 protein binding	1/721	42/18639	0.0238095238095238	0.615514166831781	0.809628327417716	0.93916885980455
GO:0141003	histone H2AX kinase activity	11/721	354/18639	0.0310734463276836	0.803298149933003	0.810893646896727	0.939424469794018
GO:0004712	protein serine/threonine/tyrosine kinase activity	1/721	43/18639	0.0232558139534884	0.601199883882205	0.817008978916981	0.944075928080161
GO:0008375	acetylglucosaminyltransferase activity	1/721	43/18639	0.0232558139534884	0.601199883882205	0.817008978916981	0.944075928080161
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	8/721	268/18639	0.0298507462686567	0.771689403192084	0.818283593799575	0.944334981804644
GO:0000049	tRNA binding	2/721	80/18639	0.025	0.64628987517337	0.82091126454499	0.946152854905059
GO:0016790	thiolester hydrolase activity	1/721	44/18639	0.0227272727272727	0.587536250157609	0.82410386632292	0.948616358289764
GO:0008094	ATP-dependent activity, acting on DNA	6/721	210/18639	0.0285714285714286	0.738617000198137	0.826689525293498	0.950375809768357
GO:0051539	4 iron, 4 sulfur cluster binding	1/721	45/18639	0.0222222222222222	0.574479889042996	0.830924039078025	0.954023896719214
GO:0005254	chloride channel activity	2/721	83/18639	0.0240963855421687	0.622930000167104	0.836408538275885	0.957881205902623
GO:0019842	vitamin binding	4/721	150/18639	0.0266666666666667	0.689375866851595	0.836768725618849	0.957881205902623
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/721	46/18639	0.0217391304347826	0.561991195802931	0.837480119954907	0.957881205902623
GO:0140097	catalytic activity, acting on DNA	10/721	336/18639	0.0297619047619048	0.769392708539726	0.841574459409261	0.961341091498
GO:0099095	ligand-gated monoatomic anion channel activity	1/721	47/18639	0.0212765957446809	0.550033936317762	0.843782321509928	0.961419907525254
GO:0140938	histone H3 methyltransferase activity	1/721	47/18639	0.0212765957446809	0.550033936317762	0.843782321509928	0.961419907525254
GO:0008188	neuropeptide receptor activity	1/721	48/18639	0.0208333333333333	0.538574895977809	0.849840461903181	0.963179133381876
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/721	48/18639	0.0208333333333333	0.538574895977809	0.849840461903181	0.963179133381876
GO:0032266	phosphatidylinositol-3-phosphate binding	1/721	48/18639	0.0208333333333333	0.538574895977809	0.849840461903181	0.963179133381876
GO:0140693	molecular condensate scaffold activity	1/721	48/18639	0.0208333333333333	0.538574895977809	0.849840461903181	0.963179133381876
GO:0050660	flavin adenine dinucleotide binding	2/721	86/18639	0.0232558139534884	0.601199883882205	0.850683239049177	0.963179133381876
GO:0004386	helicase activity	4/721	155/18639	0.0258064516129032	0.667137935662834	0.854762933143209	0.966384319243915
GO:0016763	pentosyltransferase activity	1/721	49/18639	0.0204081632653061	0.527583571570098	0.855663980109184	0.966384319243915
GO:0015605	organophosphate ester transmembrane transporter activity	1/721	50/18639	0.02	0.517031900138696	0.861261950541743	0.971486190134287
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/721	52/18639	0.0192307692307692	0.49714605782567	0.871815806765789	0.981105090781152
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	2/721	91/18639	0.021978021978022	0.568166923229337	0.87197215521039	0.981105090781152
GO:0140296	general transcription initiation factor binding	1/721	53/18639	0.0188679245283019	0.487765943527072	0.876788142447817	0.984060599326577
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/721	53/18639	0.0188679245283019	0.487765943527072	0.876788142447817	0.984060599326577
GO:0051213	dioxygenase activity	2/721	93/18639	0.021505376344086	0.555948279719028	0.879677809670735	0.986072756725674
GO:0017069	snRNA binding	1/721	54/18639	0.0185185185185185	0.478733240869163	0.8815678556349	0.986960774863979
GO:0016798	hydrolase activity, acting on glycosyl bonds	3/721	130/18639	0.0230769230769231	0.596575269390803	0.883496260279855	0.987889475113918
GO:0015103	inorganic anion transmembrane transporter activity	4/721	165/18639	0.0242424242424242	0.62670533350145	0.88572880243983	0.989155519743363
GO:0016887	ATP hydrolysis activity	12/721	417/18639	0.0287769784172662	0.743930791566469	0.886837710859688	0.989165139035806
GO:0030170	pyridoxal phosphate binding	1/721	56/18639	0.0178571428571429	0.461635625123836	0.890578934646134	0.9921071403307
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/721	57/18639	0.0175438596491228	0.453536754507628	0.894824351861877	0.994372178397809
GO:0070279	vitamin B6 binding	1/721	57/18639	0.0175438596491228	0.453536754507628	0.894824351861877	0.994372178397809
GO:0004879	nuclear receptor activity	1/721	59/18639	0.0169491525423729	0.438162627236183	0.9028280578457	0.997591614828771
GO:0015459	potassium channel regulator activity	1/721	59/18639	0.0169491525423729	0.438162627236183	0.9028280578457	0.997591614828771
GO:0070063	RNA polymerase binding	1/721	59/18639	0.0169491525423729	0.438162627236183	0.9028280578457	0.997591614828771
GO:0070888	E-box binding	1/721	59/18639	0.0169491525423729	0.438162627236183	0.9028280578457	0.997591614828771
GO:0001098	basal transcription machinery binding	1/721	60/18639	0.0166666666666667	0.430859916782247	0.906598831273755	0.997591614828771
GO:0001099	basal RNA polymerase II transcription machinery binding	1/721	60/18639	0.0166666666666667	0.430859916782247	0.906598831273755	0.997591614828771
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/721	60/18639	0.0166666666666667	0.430859916782247	0.906598831273755	0.997591614828771
GO:0098531	ligand-modulated transcription factor activity	1/721	60/18639	0.0166666666666667	0.430859916782247	0.906598831273755	0.997591614828771
GO:0008017	microtubule binding	7/721	276/18639	0.0253623188405797	0.655656395103419	0.913007606004403	0.999970286949099
GO:0022843	voltage-gated monoatomic cation channel activity	3/721	143/18639	0.020979020979021	0.54234115399164	0.918514051760049	0.999970286949099
GO:0000149	SNARE binding	2/721	106/18639	0.0188679245283019	0.487765943527072	0.92017301198815	0.999970286949099
GO:0004843	cysteine-type deubiquitinase activity	2/721	108/18639	0.0185185185185185	0.478733240869163	0.925128344038734	0.999970286949099
GO:0008173	RNA methyltransferase activity	1/721	67/18639	0.0149253731343284	0.385844701596042	0.929204464020221	0.999970286949099
GO:0042054	histone methyltransferase activity	1/721	67/18639	0.0149253731343284	0.385844701596042	0.929204464020221	0.999970286949099
GO:0005548	phospholipid transporter activity	1/721	68/18639	0.0147058823529412	0.380170514807865	0.931952879992729	0.999970286949099
GO:0015631	tubulin binding	10/721	385/18639	0.025974025974026	0.671470000180125	0.932475380351312	0.999970286949099
GO:0016279	protein-lysine N-methyltransferase activity	1/721	69/18639	0.0144927536231884	0.374660797201954	0.934594739533154	0.999970286949099
GO:0016278	lysine N-methyltransferase activity	1/721	70/18639	0.0142857142857143	0.369308500099069	0.937134168332109	0.999970286949099
GO:0016782	transferase activity, transferring sulphur-containing groups	1/721	70/18639	0.0142857142857143	0.369308500099069	0.937134168332109	0.999970286949099
GO:0140299	molecular sensor activity	1/721	71/18639	0.0140845070422535	0.364106971928659	0.939575132553799	0.999970286949099
GO:0101005	deubiquitinase activity	2/721	115/18639	0.0173913043478261	0.449592956642345	0.940280185590878	0.999970286949099
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/721	73/18639	0.0136986301369863	0.354131438451162	0.944176771013113	0.999970286949099
GO:0003724	RNA helicase activity	1/721	77/18639	0.012987012987013	0.335735000090063	0.952356670166856	0.999970286949099
GO:0008528	G protein-coupled peptide receptor activity	2/721	122/18639	0.0163934426229508	0.423796639457948	0.952490095480109	0.999970286949099
GO:0015081	sodium ion transmembrane transporter activity	3/721	164/18639	0.0182926829268293	0.472895030614661	0.955344983984026	0.999970286949099
GO:0005267	potassium channel activity	2/721	124/18639	0.0161290322580645	0.416961209789271	0.955515475281895	0.999970286949099
GO:0008186	ATP-dependent activity, acting on RNA	1/721	79/18639	0.0126582278481013	0.327235379834618	0.95598608389882	0.999970286949099
GO:0019783	ubiquitin-like protein peptidase activity	2/721	127/18639	0.015748031496063	0.407111732392674	0.95971042080016	0.999970286949099
GO:0001653	peptide receptor activity	2/721	128/18639	0.015625	0.403931171983356	0.961022488794248	0.999970286949099
GO:0031490	chromatin DNA binding	2/721	128/18639	0.015625	0.403931171983356	0.961022488794248	0.999970286949099
GO:0030165	PDZ domain binding	1/721	83/18639	0.0120481927710843	0.311465000083552	0.962437501624489	0.999970286949099
GO:0022836	gated channel activity	7/721	318/18639	0.0220125786163522	0.569060267448251	0.965074227487695	0.999970286949099
GO:0005244	voltage-gated monoatomic ion channel activity	3/721	173/18639	0.0173410404624277	0.448293555033552	0.965760683500015	0.999970286949099
GO:0022832	voltage-gated channel activity	3/721	175/18639	0.0171428571428571	0.443170200118883	0.967741545201789	0.999970286949099
GO:0015291	secondary active transmembrane transporter activity	6/721	287/18639	0.0209059233449477	0.540451463559613	0.968138992562488	0.999970286949099
GO:0003727	single-stranded RNA binding	1/721	89/18639	0.0112359550561798	0.290467359628481	0.970387656783559	0.999970286949099
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	3/721	181/18639	0.0165745856353591	0.428479475253063	0.973054712080654	0.999970286949099
GO:0003730	mRNA 3'-UTR binding	5/721	262/18639	0.0190839694656489	0.493351049750664	0.975959182253555	0.999970286949099
GO:0008276	protein methyltransferase activity	1/721	95/18639	0.0105263157894737	0.272122052704577	0.976656982481808	0.999970286949099
GO:0016407	acetyltransferase activity	1/721	96/18639	0.0104166666666667	0.269287447988904	0.977564570684494	0.999970286949099
GO:0030594	neurotransmitter receptor activity	1/721	97/18639	0.0103092783505155	0.266511288731287	0.978436918445724	0.999970286949099
GO:0005249	voltage-gated potassium channel activity	1/721	98/18639	0.0102040816326531	0.263791785785049	0.979275392278138	0.999970286949099
GO:0008170	N-methyltransferase activity	1/721	98/18639	0.0102040816326531	0.263791785785049	0.979275392278138	0.999970286949099
GO:0030527	structural constituent of chromatin	1/721	98/18639	0.0102040816326531	0.263791785785049	0.979275392278138	0.999970286949099
GO:0000287	magnesium ion binding	4/721	230/18639	0.0173913043478261	0.449592956642345	0.979536664851448	0.999970286949099
GO:0046873	metal ion transmembrane transporter activity	10/721	450/18639	0.0222222222222222	0.574479889042996	0.981731545734255	0.999970286949099
GO:0045182	translation regulator activity	7/721	356/18639	0.0196629213483146	0.508317879349842	0.985794342484696	0.999970286949099
GO:0015079	potassium ion transmembrane transporter activity	2/721	160/18639	0.0125	0.323144937586685	0.986770802169813	0.999970286949099
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/721	167/18639	0.0119760479041916	0.309599940202812	0.989604798225145	0.999970286949099
GO:0001216	DNA-binding transcription activator activity	10/721	491/18639	0.0203665987780041	0.526509063277695	0.992650430464876	0.999970286949099
GO:0140098	catalytic activity, acting on RNA	7/721	387/18639	0.0180878552971576	0.467599909686159	0.993472372643402	0.999970286949099
GO:0140767	enzyme-substrate adaptor activity	1/721	139/18639	0.00719424460431655	0.185982697891617	0.995931218089799	0.999970286949099
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	9/721	484/18639	0.0185950413223141	0.48071147740168	0.996313707146689	0.999970286949099
GO:0035403	histone H3T6 kinase activity	3/721	247/18639	0.0121457489878543	0.313986983889896	0.996620958833617	0.999970286949099
GO:0008194	UDP-glycosyltransferase activity	1/721	145/18639	0.00689655172413793	0.178286862116792	0.996794736499102	0.999970286949099
GO:0008168	methyltransferase activity	2/721	204/18639	0.00980392156862745	0.25344700987191	0.997156147664638	0.999970286949099
GO:0004674	protein serine/threonine kinase activity	7/721	433/18639	0.0161662817551963	0.417924168703334	0.998063776727441	0.999970286949099
GO:0016741	transferase activity, transferring one-carbon groups	2/721	215/18639	0.00930232558139535	0.240479953552882	0.998077271052148	0.999970286949099
GO:0016757	glycosyltransferase activity	3/721	267/18639	0.0112359550561798	0.290467359628481	0.998248143049806	0.999970286949099
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	2/721	229/18639	0.00873362445414847	0.225778122331308	0.998835634984409	0.999970286949099
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	2/721	243/18639	0.00823045267489712	0.212770329275184	0.999297333120237	0.999970286949099
GO:0004676	3-phosphoinositide-dependent protein kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0004711	ribosomal protein S6 kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0035175	histone H3S10 kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0035979	histone H2AXS139 kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0044022	histone H3S28 kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0044023	histone H4S1 kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0044024	histone H2AS1 kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0044025	histone H2BS14 kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0072354	histone H3T3 kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0072371	histone H2AS121 kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0072518	Rho-dependent protein serine/threonine kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0140823	histone H2BS36 kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0140855	histone H3S57 kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0140995	histone H2A kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0140997	histone H4 kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0140998	histone H2B kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:1990244	histone H2AT120 kinase activity	2/721	245/18639	0.00816326530612245	0.211033428628039	0.999346418084357	0.999970286949099
GO:0004677	DNA-dependent protein kinase activity	2/721	246/18639	0.00813008130081301	0.210175569162072	0.999369674480873	0.999970286949099
GO:0140857	histone H3T45 kinase activity	2/721	246/18639	0.00813008130081301	0.210175569162072	0.999369674480873	0.999970286949099
GO:0035402	histone H3T11 kinase activity	2/721	247/18639	0.00809716599190283	0.209324655926598	0.999392112975953	0.999970286949099
GO:0004679	AMP-activated protein kinase activity	2/721	248/18639	0.00806451612903226	0.208480604894636	0.999413761928642	0.999970286949099
GO:0061630	ubiquitin protein ligase activity	4/721	353/18639	0.0113314447592068	0.292935920758468	0.999515004299543	0.999970286949099
GO:0016758	hexosyltransferase activity	1/721	197/18639	0.0050761421319797	0.131226370593578	0.999595840960152	0.999970286949099
GO:0061659	ubiquitin-like protein ligase activity	4/721	372/18639	0.010752688172043	0.277974139859514	0.99973785786641	0.999970286949099
GO:0004842	ubiquitin-protein transferase activity	5/721	449/18639	0.0111358574610245	0.287879677137359	0.999901647240543	0.999970286949099
GO:0016755	aminoacyltransferase activity	6/721	496/18639	0.0120967741935484	0.312720907341953	0.999907291806182	0.999970286949099
GO:0106310	protein serine kinase activity	3/721	361/18639	0.00831024930747922	0.214833199503613	0.999929049012757	0.999970286949099
GO:0019787	ubiquitin-like protein transferase activity	5/721	479/18639	0.0104384133611691	0.269849634727921	0.99996246734364	0.999970286949099
GO:0030371	translation repressor activity	2/721	329/18639	0.0060790273556231	0.157152553233646	0.999970286949099	0.999970286949099