ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	56/599	175/18639	0.32	9.95739565943239	1.6558233668883e-40	1.39917074502061e-37
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	28/599	68/18639	0.411764705882353	12.8128252970637	2.52766088524493e-24	1.06793672401598e-21
GO:0009055	electron transfer activity	33/599	116/18639	0.28448275862069	8.85221058085315	1.85309990311793e-22	5.2195647271155e-20
GO:0015078	proton transmembrane transporter activity	40/599	185/18639	0.216216216216216	6.72797004015702	4.35655686735067e-22	9.20322638227829e-20
GO:0022853	active monoatomic ion transmembrane transporter activity	32/599	118/18639	0.271186440677966	8.43847089782406	4.11563320005628e-21	6.95542010809511e-19
GO:0008137	NADH dehydrogenase (ubiquinone) activity	18/599	41/18639	0.439024390243902	13.6610611181237	1.05588427889525e-16	1.48703702611082e-14
GO:0015399	primary active transmembrane transporter activity	32/599	166/18639	0.192771084337349	5.99843112013999	2.27127386404448e-16	2.74175202159655e-14
GO:0003954	NADH dehydrogenase activity	18/599	44/18639	0.409090909090909	12.7296251327971	4.91591379836023e-16	5.19243394951799e-14
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	19/599	58/18639	0.327586206896552	10.1934546082551	9.54508910822221e-15	8.96177810716419e-13
GO:0016651	oxidoreductase activity, acting on NAD(P)H	22/599	88/18639	0.25	7.77921535893155	4.06722576670449e-14	3.4368057728653e-12
GO:0005201	extracellular matrix structural constituent	24/599	168/18639	0.142857142857143	4.44526591938946	9.01850016600695e-10	6.92784785479624e-08
GO:0019843	rRNA binding	15/599	65/18639	0.230769230769231	7.18081417747528	1.58779807714353e-09	1.1180744793219e-07
GO:0023026	MHC class II protein complex binding	9/599	27/18639	0.333333333333333	10.3722871452421	9.61564528599611e-08	6.25016943589747e-06
GO:0004129	cytochrome-c oxidase activity	7/599	15/18639	0.466666666666667	14.5212020033389	1.75779574482569e-07	9.90224936251804e-06
GO:0055105	ubiquitin-protein transferase inhibitor activity	7/599	15/18639	0.466666666666667	14.5212020033389	1.75779574482569e-07	9.90224936251804e-06
GO:0005178	integrin binding	20/599	161/18639	0.124223602484472	3.86544862555605	2.41982551956238e-07	1.27797035251888e-05
GO:0022804	active transmembrane transporter activity	37/599	457/18639	0.0809628008752735	2.51930825628418	2.71583656208021e-07	1.34993052644575e-05
GO:0016675	oxidoreductase activity, acting on a heme group of donors	7/599	16/18639	0.4375	13.6136268781302	3.03837912782817e-07	1.42635020167489e-05
GO:0048407	platelet-derived growth factor binding	6/599	11/18639	0.545454545454545	16.9728335103961	4.32629018952302e-07	1.92406063691945e-05
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	7/599	18/18639	0.388888888888889	12.1010016694491	7.99058814117885e-07	3.37602348964807e-05
GO:0023023	MHC protein complex binding	9/599	37/18639	0.243243243243243	7.56896629517665	1.91471555960027e-06	7.70445070410585e-05
GO:0003779	actin binding	34/599	443/18639	0.0767494356659142	2.38820155488644	2.74997154571443e-06	0.000105461091708321
GO:0005518	collagen binding	12/599	72/18639	0.166666666666667	5.18614357262104	2.87053859087738e-06	0.000105461091708321
GO:0038024	cargo receptor activity	11/599	65/18639	0.169230769230769	5.26593039681521	6.37850925802014e-06	0.000224576680126126
GO:0045296	cadherin binding	27/599	334/18639	0.0808383233532934	2.51543490648086	1.15360065911853e-05	0.000389917022782062
GO:0050786	RAGE receptor binding	5/599	11/18639	0.454545454545455	14.1440279253301	1.32618019002761e-05	0.000415045281693825
GO:1990948	ubiquitin ligase inhibitor activity	5/599	11/18639	0.454545454545455	14.1440279253301	1.32618019002761e-05	0.000415045281693825
GO:0051015	actin filament binding	20/599	209/18639	0.0956937799043062	2.97769008954318	1.42653357706707e-05	0.00043050745450774
GO:0015252	proton channel activity	7/599	27/18639	0.259259259259259	8.06733444629939	1.73282941908126e-05	0.000504910641077126
GO:0043394	proteoglycan binding	8/599	37/18639	0.216216216216216	6.72797004015702	1.83841184500155e-05	0.000517819336342104
GO:0002020	protease binding	15/599	136/18639	0.110294117647059	3.43200677599921	3.23385715071153e-05	0.000853940403859765
GO:0019838	growth factor binding	15/599	136/18639	0.110294117647059	3.43200677599921	3.23385715071153e-05	0.000853940403859765
GO:0001968	fibronectin binding	7/599	30/18639	0.233333333333333	7.26060100166945	3.65312684705608e-05	0.00093542187447345
GO:0005539	glycosaminoglycan binding	21/599	242/18639	0.0867768595041322	2.70022351301756	3.8300603269867e-05	0.000951882640089341
GO:0061134	peptidase regulator activity	20/599	226/18639	0.0884955752212389	2.75370455183418	4.41621399929531e-05	0.00106620023697273
GO:0004857	enzyme inhibitor activity	29/599	416/18639	0.0697115384615385	2.16920428277899	8.49904156960634e-05	0.00199491392397704
GO:0048027	mRNA 5'-UTR binding	6/599	24/18639	0.25	7.77921535893155	8.81703369971541e-05	0.00201361985844852
GO:0055106	ubiquitin-protein transferase regulator activity	7/599	36/18639	0.194444444444444	6.05050083472454	0.000126722473256177	0.00281790762898604
GO:0033218	amide binding	20/599	247/18639	0.0809716599190283	2.51958392192115	0.000150741617156806	0.0032660683717308
GO:0140375	immune receptor activity	15/599	156/18639	0.0961538461538462	2.99200590728137	0.000156260273703778	0.00330099828199231
GO:0042277	peptide binding	20/599	249/18639	0.0803212851405622	2.49934630005833	0.000167991260989132	0.00346225891550772
GO:0032395	MHC class II receptor activity	4/599	10/18639	0.4	12.4467445742905	0.000190008405217153	0.0038227881525832
GO:0001540	amyloid-beta binding	10/599	83/18639	0.120481927710843	3.74901945008749	0.00032159830395711	0.00631978062427344
GO:0070325	lipoprotein particle receptor binding	6/599	31/18639	0.193548387096774	6.02261834239862	0.000398358251597139	0.00765028914999051
GO:0016209	antioxidant activity	10/599	86/18639	0.116279069767442	3.61823970182863	0.000429631465323114	0.00806752418217848
GO:0008201	heparin binding	15/599	172/18639	0.0872093023255814	2.71367977637147	0.000451625667540096	0.00829616715372567
GO:0030020	extracellular matrix structural constituent conferring tensile strength	7/599	44/18639	0.159090909090909	4.95040977386553	0.000465796863396067	0.00837443296956758
GO:0042605	peptide antigen binding	7/599	45/18639	0.155555555555556	4.84040066777963	0.000536522019306255	0.00944502304820387
GO:0030021	extracellular matrix structural constituent conferring compression resistance	5/599	22/18639	0.227272727272727	7.07201396266505	0.000563565732503617	0.00971863355031747
GO:0030414	peptidase inhibitor activity	14/599	169/18639	0.0828402366863905	2.57772816627318	0.00114362273635337	0.0193272242443719
GO:0050750	low-density lipoprotein particle receptor binding	5/599	26/18639	0.192307692307692	5.98401181456273	0.00126598631500291	0.0209756556113227
GO:0005080	protein kinase C binding	7/599	52/18639	0.134615384615385	4.18880827019391	0.00130329683271403	0.021178573531603
GO:0050840	extracellular matrix binding	8/599	67/18639	0.119402985074627	3.71544614157925	0.00133470402530784	0.0212797151204741
GO:1901681	sulfur compound binding	19/599	275/18639	0.0690909090909091	2.14989224465017	0.00151145059086318	0.0232469127229203
GO:0005044	scavenger receptor activity	5/599	27/18639	0.185185185185185	5.7623817473567	0.0015131126624386	0.0232469127229203
GO:0097110	scaffold protein binding	8/599	70/18639	0.114285714285714	3.55621273551157	0.00177642573967695	0.0268049955361969
GO:0031625	ubiquitin protein ligase binding	20/599	302/18639	0.0662251655629139	2.06071930037922	0.00190522958562228	0.0282441929798391
GO:0004197	cysteine-type endopeptidase activity	9/599	88/18639	0.102272727272727	3.18240628319927	0.00205914595539616	0.0299996264191337
GO:0042056	chemoattractant activity	6/599	42/18639	0.142857142857143	4.44526591938946	0.00210507863885898	0.0301490076243362
GO:0098631	cell adhesion mediator activity	8/599	76/18639	0.105263157894737	3.2754590984975	0.00300133160559111	0.0422687534454081
GO:0016175	superoxide-generating NAD(P)H oxidase activity	3/599	10/18639	0.3	9.33505843071786	0.0033468755894838	0.0459792676881736
GO:0004180	carboxypeptidase activity	6/599	46/18639	0.130434782608696	4.05872105683385	0.00337362674161747	0.0459792676881736
GO:0004867	serine-type endopeptidase inhibitor activity	9/599	95/18639	0.0947368421052632	2.94791318864775	0.00347685716810277	0.0466340366197911
GO:0005504	fatty acid binding	6/599	47/18639	0.127659574468085	3.97236528966718	0.00376437761677036	0.0497015482214212
GO:0044389	ubiquitin-like protein ligase binding	20/599	322/18639	0.062111801242236	1.93272431277803	0.00396380680403364	0.0515294884524373
GO:0048306	calcium-dependent protein binding	8/599	80/18639	0.1	3.11168614357262	0.0041279207036629	0.0528498938575023
GO:0019864	IgG binding	3/599	11/18639	0.272727272727273	8.48641675519806	0.00449282651144446	0.056663259733889
GO:0008135	translation factor activity, RNA binding	8/599	83/18639	0.0963855421686747	2.99921556007	0.00516765496513418	0.0642157124343879
GO:0180051	translation factor activity	8/599	84/18639	0.0952380952380952	2.96351061292631	0.00555526442707662	0.0647119452975953
GO:0008238	exopeptidase activity	9/599	102/18639	0.0882352941176471	2.74560542079937	0.00556772382402419	0.0647119452975953
GO:0003743	translation initiation factor activity	6/599	51/18639	0.117647058823529	3.6608072277325	0.00566890509308598	0.0647119452975953
GO:0005158	insulin receptor binding	4/599	23/18639	0.173913043478261	5.41162807577847	0.00574889872983115	0.0647119452975953
GO:0017134	fibroblast growth factor binding	4/599	23/18639	0.173913043478261	5.41162807577847	0.00574889872983115	0.0647119452975953
GO:0004875	complement receptor activity	3/599	12/18639	0.25	7.77921535893155	0.00584862099807594	0.0647119452975953
GO:0070008	serine-type exopeptidase activity	3/599	12/18639	0.25	7.77921535893155	0.00584862099807594	0.0647119452975953
GO:0097371	MDM2/MDM4 family protein binding	3/599	12/18639	0.25	7.77921535893155	0.00584862099807594	0.0647119452975953
GO:0004866	endopeptidase inhibitor activity	12/599	161/18639	0.0745341614906832	2.31926917533363	0.0058968281513785	0.0647119452975953
GO:0061135	endopeptidase regulator activity	13/599	184/18639	0.0706521739130435	2.198473905785	0.0066271042532475	0.0717936294101812
GO:0019955	cytokine binding	11/599	144/18639	0.0763888888888889	2.37698247078464	0.00685634919587663	0.0733368996267817
GO:0019865	immunoglobulin binding	4/599	26/18639	0.153846153846154	4.78720945165019	0.00899667993655004	0.0950274318298098
GO:0044548	S100 protein binding	3/599	14/18639	0.214285714285714	6.66789887908419	0.00922520221815048	0.0962382206708291
GO:0004601	peroxidase activity	6/599	57/18639	0.105263157894737	3.2754590984975	0.00972378578080361	0.0989951684913139
GO:0016504	peptidase activator activity	6/599	57/18639	0.105263157894737	3.2754590984975	0.00972378578080361	0.0989951684913139
GO:0005200	structural constituent of cytoskeleton	9/599	112/18639	0.0803571428571429	2.50046207965657	0.0100961465863491	0.101562426969821
GO:0004364	glutathione transferase activity	4/599	27/18639	0.148148148148148	4.60990539788536	0.0102981698972651	0.102375924272812
GO:0005041	low-density lipoprotein particle receptor activity	3/599	15/18639	0.2	6.22337228714524	0.0112599048674515	0.108120677420415
GO:0031386	protein tag activity	3/599	15/18639	0.2	6.22337228714524	0.0112599048674515	0.108120677420415
GO:0141047	molecular tag activity	3/599	15/18639	0.2	6.22337228714524	0.0112599048674515	0.108120677420415
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	6/599	59/18639	0.101694915254237	3.16442658668402	0.0114444683028955	0.108658154111761
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	4/599	29/18639	0.137931034482759	4.29198088768637	0.0132522397338102	0.121648601752717
GO:0033293	monocarboxylic acid binding	7/599	79/18639	0.0886075949367089	2.75719025379852	0.0134767846015903	0.121648601752717
GO:0005159	insulin-like growth factor receptor binding	3/599	16/18639	0.1875	5.83441151919866	0.0135325071772254	0.121648601752717
GO:0017070	U6 snRNA binding	3/599	16/18639	0.1875	5.83441151919866	0.0135325071772254	0.121648601752717
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/599	16/18639	0.1875	5.83441151919866	0.0135325071772254	0.121648601752717
GO:0005507	copper ion binding	6/599	63/18639	0.0952380952380952	2.96351061292631	0.0155100990296883	0.135594156342537
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/599	17/18639	0.176470588235294	5.49121084159874	0.0160466457210103	0.135594156342537
GO:0019198	transmembrane receptor protein phosphatase activity	3/599	17/18639	0.176470588235294	5.49121084159874	0.0160466457210103	0.135594156342537
GO:0030169	low-density lipoprotein particle binding	3/599	17/18639	0.176470588235294	5.49121084159874	0.0160466457210103	0.135594156342537
GO:0036041	long-chain fatty acid binding	3/599	17/18639	0.176470588235294	5.49121084159874	0.0160466457210103	0.135594156342537
GO:0048038	quinone binding	3/599	17/18639	0.176470588235294	5.49121084159874	0.0160466457210103	0.135594156342537
GO:0005516	calmodulin binding	13/599	207/18639	0.0628019323671498	1.95419902736445	0.0166364153916685	0.139185851544158
GO:0061749	forked DNA-dependent helicase activity	5/599	47/18639	0.106382978723404	3.31030440805598	0.0170142122763908	0.139582615277187
GO:1990518	single-stranded 3'-5' DNA helicase activity	5/599	47/18639	0.106382978723404	3.31030440805598	0.0170142122763908	0.139582615277187
GO:0008234	cysteine-type peptidase activity	12/599	187/18639	0.0641711229946524	1.99680394239954	0.0179644618337713	0.141875565063445
GO:0009378	four-way junction helicase activity	5/599	48/18639	0.104166666666667	3.24133973288815	0.0185056672420415	0.141875565063445
GO:0036121	double-stranded DNA helicase activity	5/599	48/18639	0.104166666666667	3.24133973288815	0.0185056672420415	0.141875565063445
GO:0043138	3'-5' DNA helicase activity	5/599	48/18639	0.104166666666667	3.24133973288815	0.0185056672420415	0.141875565063445
GO:0031369	translation initiation factor binding	4/599	32/18639	0.125	3.88960767946578	0.0186087307760941	0.141875565063445
GO:0071813	lipoprotein particle binding	4/599	32/18639	0.125	3.88960767946578	0.0186087307760941	0.141875565063445
GO:0071814	protein-lipid complex binding	4/599	32/18639	0.125	3.88960767946578	0.0186087307760941	0.141875565063445
GO:0030228	lipoprotein particle receptor activity	3/599	18/18639	0.166666666666667	5.18614357262104	0.018804808623794	0.141875565063445
GO:0098641	cadherin binding involved in cell-cell adhesion	3/599	18/18639	0.166666666666667	5.18614357262104	0.018804808623794	0.141875565063445
GO:0043395	heparan sulfate proteoglycan binding	3/599	19/18639	0.157894736842105	4.91318864774624	0.0218084266954877	0.163080712899886
GO:0016004	phospholipase activator activity	3/599	20/18639	0.15	4.66752921535893	0.0250579592359564	0.184121526559854
GO:0016505	peptidase activator activity involved in apoptotic process	3/599	20/18639	0.15	4.66752921535893	0.0250579592359564	0.184121526559854
GO:0017046	peptide hormone binding	5/599	53/18639	0.0943396226415094	2.93555296563455	0.0272474707063297	0.198483730576281
GO:0098632	cell-cell adhesion mediator activity	5/599	55/18639	0.0909090909090909	2.82880558506602	0.0313691757854989	0.226555158450825
GO:0017124	SH3 domain binding	8/599	115/18639	0.0695652173913043	2.16465123031139	0.0321109093650119	0.229946766215551
GO:0000146	microfilament motor activity	4/599	38/18639	0.105263157894737	3.2754590984975	0.0328851246756942	0.231566086258014
GO:0043531	ADP binding	4/599	38/18639	0.105263157894737	3.2754590984975	0.0328851246756942	0.231566086258014
GO:0004602	glutathione peroxidase activity	3/599	23/18639	0.130434782608696	4.05872105683385	0.0362737262866483	0.253316518282792
GO:0017116	single-stranded DNA helicase activity	5/599	58/18639	0.0862068965517241	2.68248805480398	0.0382481953605478	0.258157634030142
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	4/599	40/18639	0.1	3.11168614357262	0.0387424608677104	0.258157634030142
GO:0050997	quaternary ammonium group binding	4/599	40/18639	0.1	3.11168614357262	0.0387424608677104	0.258157634030142
GO:0005131	growth hormone receptor binding	2/599	10/18639	0.2	6.22337228714524	0.0391055350956901	0.258157634030142
GO:0005381	iron ion transmembrane transporter activity	2/599	10/18639	0.2	6.22337228714524	0.0391055350956901	0.258157634030142
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/599	10/18639	0.2	6.22337228714524	0.0391055350956901	0.258157634030142
GO:0043422	protein kinase B binding	2/599	10/18639	0.2	6.22337228714524	0.0391055350956901	0.258157634030142
GO:0005540	hyaluronic acid binding	3/599	24/18639	0.125	3.88960767946578	0.0404948064064672	0.261206957354693
GO:0050699	WW domain binding	3/599	24/18639	0.125	3.88960767946578	0.0404948064064672	0.261206957354693
GO:0060229	lipase activator activity	3/599	24/18639	0.125	3.88960767946578	0.0404948064064672	0.261206957354693
GO:0042169	SH2 domain binding	4/599	41/18639	0.0975609756097561	3.03579135958304	0.0418801242262922	0.268096249781946
GO:0016874	ligase activity	10/599	167/18639	0.0598802395209581	1.86328511591175	0.0436104219858342	0.277073733669398
GO:0120020	cholesterol transfer activity	3/599	25/18639	0.12	3.73402337228714	0.0449521878542157	0.28045159330977
GO:0008307	structural constituent of muscle	4/599	42/18639	0.0952380952380952	2.96351061292631	0.0451571906499971	0.28045159330977
GO:0001851	complement component C3b binding	2/599	11/18639	0.181818181818182	5.65761117013204	0.0467972481144113	0.28045159330977
GO:0008199	ferric iron binding	2/599	11/18639	0.181818181818182	5.65761117013204	0.0467972481144113	0.28045159330977
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/599	11/18639	0.181818181818182	5.65761117013204	0.0467972481144113	0.28045159330977
GO:0032050	clathrin heavy chain binding	2/599	11/18639	0.181818181818182	5.65761117013204	0.0467972481144113	0.28045159330977
GO:0042608	T cell receptor binding	2/599	11/18639	0.181818181818182	5.65761117013204	0.0467972481144113	0.28045159330977
GO:0140031	phosphorylation-dependent protein binding	2/599	11/18639	0.181818181818182	5.65761117013204	0.0467972481144113	0.28045159330977
GO:0030247	polysaccharide binding	3/599	26/18639	0.115384615384615	3.59040708873764	0.0496420367130416	0.293339307849791
GO:0043548	phosphatidylinositol 3-kinase binding	3/599	26/18639	0.115384615384615	3.59040708873764	0.0496420367130416	0.293339307849791
GO:0030547	signaling receptor inhibitor activity	4/599	44/18639	0.0909090909090909	2.82880558506602	0.0521283749114426	0.305892200001174
GO:0004032	aldose reductase (NADPH) activity	2/599	12/18639	0.166666666666667	5.18614357262104	0.0549869735376784	0.313945896211745
GO:0004859	phospholipase inhibitor activity	2/599	12/18639	0.166666666666667	5.18614357262104	0.0549869735376784	0.313945896211745
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/599	12/18639	0.166666666666667	5.18614357262104	0.0549869735376784	0.313945896211745
GO:0035259	nuclear glucocorticoid receptor binding	2/599	12/18639	0.166666666666667	5.18614357262104	0.0549869735376784	0.313945896211745
GO:0008009	chemokine activity	4/599	45/18639	0.0888888888888889	2.76594323873122	0.0558213679992735	0.316570845365008
GO:0035325	Toll-like receptor binding	2/599	13/18639	0.153846153846154	4.78720945165019	0.0636348746420286	0.358476460483428
GO:0004181	metallocarboxypeptidase activity	3/599	29/18639	0.103448275862069	3.21898566576478	0.065060871494402	0.361687081662959
GO:0043236	laminin binding	3/599	29/18639	0.103448275862069	3.21898566576478	0.065060871494402	0.361687081662959
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/599	30/18639	0.1	3.11168614357262	0.0706330291905946	0.381578662146235
GO:0031210	phosphatidylcholine binding	3/599	30/18639	0.1	3.11168614357262	0.0706330291905946	0.381578662146235
GO:0048019	receptor antagonist activity	3/599	30/18639	0.1	3.11168614357262	0.0706330291905946	0.381578662146235
GO:0044325	transmembrane transporter binding	8/599	136/18639	0.0588235294117647	1.83040361386625	0.0723025113120385	0.381578662146235
GO:0005161	platelet-derived growth factor receptor binding	2/599	14/18639	0.142857142857143	4.44526591938946	0.0727031533793417	0.381578662146235
GO:0008191	metalloendopeptidase inhibitor activity	2/599	14/18639	0.142857142857143	4.44526591938946	0.0727031533793417	0.381578662146235
GO:0016530	metallochaperone activity	2/599	14/18639	0.142857142857143	4.44526591938946	0.0727031533793417	0.381578662146235
GO:0019763	immunoglobulin receptor activity	2/599	14/18639	0.142857142857143	4.44526591938946	0.0727031533793417	0.381578662146235
GO:0032036	myosin heavy chain binding	2/599	14/18639	0.142857142857143	4.44526591938946	0.0727031533793417	0.381578662146235
GO:0008083	growth factor activity	9/599	162/18639	0.0555555555555556	1.72871452420701	0.0781494879816831	0.407631588546433
GO:0003712	transcription coregulator activity	22/599	495/18639	0.0444444444444444	1.38297161936561	0.0791235066822001	0.410180142002816
GO:0005523	tropomyosin binding	2/599	15/18639	0.133333333333333	4.14891485809683	0.0821559608427095	0.416891810050442
GO:0050780	dopamine receptor binding	2/599	15/18639	0.133333333333333	4.14891485809683	0.0821559608427095	0.416891810050442
GO:0051371	muscle alpha-actinin binding	2/599	15/18639	0.133333333333333	4.14891485809683	0.0821559608427095	0.416891810050442
GO:0120015	sterol transfer activity	3/599	32/18639	0.09375	2.91720575959933	0.0823916358324543	0.416891810050442
GO:0004896	cytokine receptor activity	6/599	96/18639	0.0625	1.94480383973289	0.0888702913913485	0.446996406105294
GO:0003678	DNA helicase activity	5/599	74/18639	0.0675675675675676	2.10249063754907	0.0894502986993874	0.447251493496937
GO:0055102	lipase inhibitor activity	2/599	16/18639	0.125	3.88960767946578	0.0919593113663501	0.457091871203328
GO:0017069	snRNA binding	4/599	54/18639	0.0740740740740741	2.30495269894268	0.095065148834415	0.461666958420004
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	4/599	54/18639	0.0740740740740741	2.30495269894268	0.095065148834415	0.461666958420004
GO:0051287	NAD binding	4/599	54/18639	0.0740740740740741	2.30495269894268	0.095065148834415	0.461666958420004
GO:0140463	chromatin-protein adaptor activity	4/599	54/18639	0.0740740740740741	2.30495269894268	0.095065148834415	0.461666958420004
GO:0008236	serine-type peptidase activity	10/599	194/18639	0.0515463917525773	1.60396192967661	0.0964237278291758	0.465588857232306
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/599	122/18639	0.0573770491803279	1.78539368893511	0.098478068373181	0.470780714431094
GO:0005154	epidermal growth factor receptor binding	3/599	35/18639	0.0857142857142857	2.66715955163368	0.101470263592158	0.470780714431094
GO:0051540	metal cluster binding	5/599	77/18639	0.0649350649350649	2.0205754179043	0.101723429427063	0.470780714431094
GO:0005092	GDP-dissociation inhibitor activity	2/599	17/18639	0.117647058823529	3.6608072277325	0.102081000119062	0.470780714431094
GO:0008429	phosphatidylethanolamine binding	2/599	17/18639	0.117647058823529	3.6608072277325	0.102081000119062	0.470780714431094
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/599	17/18639	0.117647058823529	3.6608072277325	0.102081000119062	0.470780714431094
GO:0016018	cyclosporin A binding	2/599	17/18639	0.117647058823529	3.6608072277325	0.102081000119062	0.470780714431094
GO:0046965	nuclear retinoid X receptor binding	2/599	17/18639	0.117647058823529	3.6608072277325	0.102081000119062	0.470780714431094
GO:0042393	histone binding	12/599	247/18639	0.048582995951417	1.51175035315269	0.102513196988546	0.470780714431094
GO:0004175	endopeptidase activity	18/599	405/18639	0.0444444444444444	1.38297161936561	0.104374708002732	0.47122839848962
GO:0019209	kinase activator activity	8/599	148/18639	0.0540540540540541	1.68199251003925	0.104881566664528	0.47122839848962
GO:0019199	transmembrane receptor protein kinase activity	5/599	78/18639	0.0641025641025641	1.99467060485424	0.10599189499235	0.47122839848962
GO:0140030	modification-dependent protein binding	9/599	173/18639	0.0520231213872832	1.61879625966206	0.106293923925516	0.47122839848962
GO:0017171	serine hydrolase activity	10/599	198/18639	0.0505050505050505	1.57155865837001	0.106522046063038	0.47122839848962
GO:0004033	aldo-keto reductase (NADPH) activity	3/599	36/18639	0.0833333333333333	2.59307178631052	0.108187348292291	0.47122839848962
GO:0044390	ubiquitin-like protein conjugating enzyme binding	3/599	36/18639	0.0833333333333333	2.59307178631052	0.108187348292291	0.47122839848962
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	3/599	36/18639	0.0833333333333333	2.59307178631052	0.108187348292291	0.47122839848962
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	3/599	36/18639	0.0833333333333333	2.59307178631052	0.108187348292291	0.47122839848962
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	3/599	36/18639	0.0833333333333333	2.59307178631052	0.108187348292291	0.47122839848962
GO:0046332	SMAD binding	5/599	79/18639	0.0632911392405063	1.96942160985609	0.110347102600935	0.477660767976357
GO:0003746	translation elongation factor activity	2/599	18/18639	0.111111111111111	3.45742904841402	0.112490524055971	0.477660767976357
GO:0035615	clathrin adaptor activity	2/599	18/18639	0.111111111111111	3.45742904841402	0.112490524055971	0.477660767976357
GO:1901611	phosphatidylglycerol binding	2/599	18/18639	0.111111111111111	3.45742904841402	0.112490524055971	0.477660767976357
GO:1990381	ubiquitin-specific protease binding	2/599	18/18639	0.111111111111111	3.45742904841402	0.112490524055971	0.477660767976357
GO:0042826	histone deacetylase binding	7/599	127/18639	0.0551181102362205	1.71510259881955	0.115189439107134	0.486675380227639
GO:0043021	ribonucleoprotein complex binding	9/599	177/18639	0.0508474576271186	1.58221329334201	0.117780823946308	0.495148239973284
GO:0001618	virus receptor activity	5/599	81/18639	0.0617283950617284	1.92079391578557	0.119312545413346	0.499104459773651
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/599	19/18639	0.105263157894737	3.2754590984975	0.12315900609838	0.505857102901271
GO:0030506	ankyrin binding	2/599	19/18639	0.105263157894737	3.2754590984975	0.12315900609838	0.505857102901271
GO:1990380	K48-linked deubiquitinase activity	2/599	19/18639	0.105263157894737	3.2754590984975	0.12315900609838	0.505857102901271
GO:0005543	phospholipid binding	21/599	497/18639	0.0422535211267606	1.31479696207294	0.123577606691305	0.505857102901271
GO:0140272	exogenous protein binding	5/599	82/18639	0.0609756097560976	1.8973695997394	0.123920024024335	0.505857102901271
GO:0031267	small GTPase binding	13/599	283/18639	0.0459363957597173	1.4293964617118	0.125973213807551	0.511766181093175
GO:0004714	transmembrane receptor protein tyrosine kinase activity	4/599	60/18639	0.0666666666666667	2.07445742904841	0.126772602787776	0.512549518448184
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3/599	39/18639	0.0769230769230769	2.39360472582509	0.129313930239846	0.520334624060335
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	4/599	61/18639	0.0655737704918033	2.04044993021155	0.132442242054101	0.53039665656737
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	7/599	132/18639	0.053030303030303	1.65013659128851	0.133283139931869	0.531246477558628
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	2/599	20/18639	0.1	3.11168614357262	0.134059122416427	0.531830790806954
GO:0019207	kinase regulator activity	13/599	287/18639	0.0452961672473868	1.40947455980641	0.135814496054618	0.536276865262392
GO:0015036	disulfide oxidoreductase activity	3/599	40/18639	0.075	2.33376460767947	0.136657562891641	0.53709600299273
GO:0051020	GTPase binding	14/599	315/18639	0.0444444444444444	1.38297161936561	0.139236272779722	0.544697456013266
GO:0042287	MHC protein binding	3/599	41/18639	0.0731707317073171	2.27684351968728	0.144139992259958	0.557565693756202
GO:0001846	opsonin binding	2/599	21/18639	0.0952380952380952	2.96351061292631	0.145165032693922	0.557565693756202
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/599	21/18639	0.0952380952380952	2.96351061292631	0.145165032693922	0.557565693756202
GO:0140312	cargo adaptor activity	2/599	21/18639	0.0952380952380952	2.96351061292631	0.145165032693922	0.557565693756202
GO:0016859	cis-trans isomerase activity	3/599	42/18639	0.0714285714285714	2.22263295969473	0.151754053922263	0.573443511942574
GO:0035198	miRNA binding	3/599	42/18639	0.0714285714285714	2.22263295969473	0.151754053922263	0.573443511942574
GO:0048487	beta-tubulin binding	3/599	42/18639	0.0714285714285714	2.22263295969473	0.151754053922263	0.573443511942574
GO:0043022	ribosome binding	6/599	112/18639	0.0535714285714286	1.66697471977105	0.152013428017913	0.573443511942574
GO:0120013	lipid transfer activity	4/599	65/18639	0.0615384615384615	1.91488378066007	0.156112710747393	0.582388566978466
GO:0034062	5'-3' RNA polymerase activity	2/599	22/18639	0.0909090909090909	2.82880558506602	0.156452313259304	0.582388566978466
GO:0097747	RNA polymerase activity	2/599	22/18639	0.0909090909090909	2.82880558506602	0.156452313259304	0.582388566978466
GO:0008200	ion channel inhibitor activity	3/599	43/18639	0.0697674418604651	2.17094382109718	0.159492601009552	0.591101964267856
GO:0030295	protein kinase activator activity	7/599	139/18639	0.0503597122302158	1.56703618741067	0.160801405779096	0.593350165429414
GO:0008235	metalloexopeptidase activity	4/599	66/18639	0.0606060606060606	1.88587039004401	0.162262585128194	0.596138627970975
GO:0016248	channel inhibitor activity	3/599	44/18639	0.0681818181818182	2.12160418879951	0.16734851999234	0.608900083950569
GO:0070577	lysine-acetylated histone binding	2/599	23/18639	0.0869565217391304	2.70581403788924	0.167897892970985	0.608900083950569
GO:0099186	structural constituent of postsynapse	2/599	23/18639	0.0869565217391304	2.70581403788924	0.167897892970985	0.608900083950569
GO:0051539	4 iron, 4 sulfur cluster binding	3/599	45/18639	0.0666666666666667	2.07445742904841	0.175314745134702	0.630387062292865
GO:0141110	transporter inhibitor activity	3/599	45/18639	0.0666666666666667	2.07445742904841	0.175314745134702	0.630387062292865
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/599	24/18639	0.0833333333333333	2.59307178631052	0.179479991749578	0.631919137618305
GO:0042625	ATPase-coupled ion transmembrane transporter activity	2/599	24/18639	0.0833333333333333	2.59307178631052	0.179479991749578	0.631919137618305
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	2/599	24/18639	0.0833333333333333	2.59307178631052	0.179479991749578	0.631919137618305
GO:0046961	proton-transporting ATPase activity, rotational mechanism	2/599	24/18639	0.0833333333333333	2.59307178631052	0.179479991749578	0.631919137618305
GO:0140033	acetylation-dependent protein binding	2/599	24/18639	0.0833333333333333	2.59307178631052	0.179479991749578	0.631919137618305
GO:0042562	hormone binding	5/599	94/18639	0.0531914893617021	1.65515220402799	0.185076913433551	0.648921128013904
GO:0001848	complement binding	2/599	25/18639	0.08	2.4893489148581	0.191178061653522	0.652660854499424
GO:0015662	P-type ion transporter activity	2/599	25/18639	0.08	2.4893489148581	0.191178061653522	0.652660854499424
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/599	25/18639	0.08	2.4893489148581	0.191178061653522	0.652660854499424
GO:0042974	nuclear retinoic acid receptor binding	2/599	25/18639	0.08	2.4893489148581	0.191178061653522	0.652660854499424
GO:0140358	P-type transmembrane transporter activity	2/599	25/18639	0.08	2.4893489148581	0.191178061653522	0.652660854499424
GO:0001784	phosphotyrosine residue binding	3/599	47/18639	0.0638297872340425	1.98618264483359	0.19155016794776	0.652660854499424
GO:0043495	protein-membrane adaptor activity	3/599	47/18639	0.0638297872340425	1.98618264483359	0.19155016794776	0.652660854499424
GO:0140693	molecular condensate scaffold activity	3/599	48/18639	0.0625	1.94480383973289	0.199805586098176	0.672595910536413
GO:0042379	chemokine receptor binding	4/599	72/18639	0.0555555555555556	1.72871452420701	0.20086149730096	0.672595910536413
GO:0001637	G protein-coupled chemoattractant receptor activity	2/599	26/18639	0.0769230769230769	2.39360472582509	0.202972730398562	0.672595910536413
GO:0004950	chemokine receptor activity	2/599	26/18639	0.0769230769230769	2.39360472582509	0.202972730398562	0.672595910536413
GO:0005112	Notch binding	2/599	26/18639	0.0769230769230769	2.39360472582509	0.202972730398562	0.672595910536413
GO:0008198	ferrous iron binding	2/599	26/18639	0.0769230769230769	2.39360472582509	0.202972730398562	0.672595910536413
GO:0120014	phospholipid transfer activity	2/599	26/18639	0.0769230769230769	2.39360472582509	0.202972730398562	0.672595910536413
GO:0004252	serine-type endopeptidase activity	8/599	176/18639	0.0454545454545455	1.41440279253301	0.206484181962675	0.681559116243986
GO:0060590	ATPase regulator activity	3/599	49/18639	0.0612244897959184	1.90511396545263	0.208143772155483	0.68436376448009
GO:0003714	transcription corepressor activity	9/599	204/18639	0.0441176470588235	1.37280271039969	0.211258525566033	0.686926993818503
GO:0000510	H3-H4 histone complex chaperone activity	7/599	151/18639	0.0463576158940397	1.44250351026545	0.213233937302081	0.686926993818503
GO:0140584	chromatin extrusion motor activity	7/599	151/18639	0.0463576158940397	1.44250351026545	0.213233937302081	0.686926993818503
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	7/599	151/18639	0.0463576158940397	1.44250351026545	0.213233937302081	0.686926993818503
GO:0140849	ATP-dependent H2AZ histone chaperone activity	7/599	151/18639	0.0463576158940397	1.44250351026545	0.213233937302081	0.686926993818503
GO:0001671	ATPase activator activity	2/599	27/18639	0.0740740740740741	2.30495269894268	0.214845747225247	0.686926993818503
GO:0035255	ionotropic glutamate receptor binding	2/599	27/18639	0.0740740740740741	2.30495269894268	0.214845747225247	0.686926993818503
GO:0005006	epidermal growth factor receptor activity	3/599	50/18639	0.06	1.86701168614357	0.216558074830043	0.686926993818503
GO:0048020	CCR chemokine receptor binding	3/599	50/18639	0.06	1.86701168614357	0.216558074830043	0.686926993818503
GO:0015616	DNA translocase activity	7/599	152/18639	0.0460526315789474	1.43301335559265	0.217865602773206	0.686926993818503
GO:0140674	ATP-dependent histone chaperone activity	7/599	152/18639	0.0460526315789474	1.43301335559265	0.217865602773206	0.686926993818503
GO:0061775	cohesin loader activity	7/599	153/18639	0.0457516339869281	1.4236472552293	0.222533197902281	0.699035510139136
GO:0005021	vascular endothelial growth factor receptor activity	3/599	51/18639	0.0588235294117647	1.83040361386625	0.225041953514086	0.700482606968954
GO:0046625	sphingolipid binding	2/599	28/18639	0.0714285714285714	2.22263295969473	0.226779931022266	0.700482606968954
GO:0051393	alpha-actinin binding	2/599	28/18639	0.0714285714285714	2.22263295969473	0.226779931022266	0.700482606968954
GO:0051959	dynein light intermediate chain binding	2/599	28/18639	0.0714285714285714	2.22263295969473	0.226779931022266	0.700482606968954
GO:0017022	myosin binding	4/599	76/18639	0.0526315789473684	1.63772954924875	0.227967712327174	0.700482606968954
GO:0051536	iron-sulfur cluster binding	4/599	76/18639	0.0526315789473684	1.63772954924875	0.227967712327174	0.700482606968954
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/599	52/18639	0.0576923076923077	1.79520354436882	0.233588985403706	0.715154683572939
GO:0003785	actin monomer binding	2/599	29/18639	0.0689655172413793	2.14599044384319	0.238759120616922	0.725088173625904
GO:0051861	glycolipid binding	2/599	29/18639	0.0689655172413793	2.14599044384319	0.238759120616922	0.725088173625904
GO:0008237	metallopeptidase activity	8/599	184/18639	0.0434782608695652	1.35290701894462	0.240956710892159	0.725088173625904
GO:0016860	intramolecular oxidoreductase activity	3/599	53/18639	0.0566037735849057	1.76133177938073	0.242192871816531	0.725088173625904
GO:0051018	protein kinase A binding	3/599	53/18639	0.0566037735849057	1.76133177938073	0.242192871816531	0.725088173625904
GO:0140658	ATP-dependent chromatin remodeler activity	7/599	158/18639	0.0443037974683544	1.37859512689926	0.246375052753297	0.725088173625904
GO:0001965	G-protein alpha-subunit binding	2/599	30/18639	0.0666666666666667	2.07445742904841	0.250768127147374	0.725088173625904
GO:0098918	structural constituent of synapse	2/599	30/18639	0.0666666666666667	2.07445742904841	0.250768127147374	0.725088173625904
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3/599	54/18639	0.0555555555555556	1.72871452420701	0.250847443756656	0.725088173625904
GO:0031406	carboxylic acid binding	8/599	187/18639	0.0427807486631016	1.33120262826636	0.254360832341996	0.725088173625904
GO:0003689	DNA clamp loader activity	7/599	160/18639	0.04375	1.36136268781302	0.25612789375363	0.725088173625904
GO:0099106	ion channel regulator activity	7/599	160/18639	0.04375	1.36136268781302	0.25612789375363	0.725088173625904
GO:0140313	molecular sequestering activity	3/599	55/18639	0.0545454545454545	1.69728335103961	0.259546666775704	0.725088173625904
GO:0043177	organic acid binding	8/599	189/18639	0.0423280423280423	1.31711582796725	0.263424402931688	0.725088173625904
GO:0005126	cytokine receptor binding	11/599	275/18639	0.04	1.24467445742905	0.271658540908289	0.725088173625904
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/599	32/18639	0.0625	1.94480383973289	0.274819425274683	0.725088173625904
GO:0140713	histone chaperone activity	7/599	164/18639	0.0426829268292683	1.32815871981758	0.275958319066478	0.725088173625904
GO:0001094	TFIID-class transcription factor complex binding	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0003796	lysozyme activity	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0004090	carbonyl reductase (NADPH) activity	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0005522	profilin binding	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0005528	FK506 binding	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0008190	eukaryotic initiation factor 4E binding	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0008239	dipeptidyl-peptidase activity	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0015203	polyamine transmembrane transporter activity	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0031720	haptoglobin binding	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0032356	oxidized DNA binding	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0043208	glycosphingolipid binding	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0047429	nucleoside triphosphate diphosphatase activity	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0051880	G-quadruplex DNA binding	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0070513	death domain binding	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:1990763	arrestin family protein binding	1/599	10/18639	0.1	3.11168614357262	0.278719116744116	0.725088173625904
GO:0140104	molecular carrier activity	10/599	249/18639	0.0401606425702811	1.24967315002917	0.280710200278887	0.725088173625904
GO:0061980	regulatory RNA binding	3/599	58/18639	0.0517241379310345	1.60949283288239	0.285854000054777	0.725088173625904
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	2/599	33/18639	0.0606060606060606	1.88587039004401	0.2868357995766	0.725088173625904
GO:0140311	protein sequestering activity	2/599	33/18639	0.0606060606060606	1.88587039004401	0.2868357995766	0.725088173625904
GO:0070851	growth factor receptor binding	6/599	139/18639	0.0431654676258993	1.34317387492343	0.289571804153988	0.725088173625904
GO:0004879	nuclear receptor activity	3/599	59/18639	0.0508474576271186	1.58221329334201	0.294674308379386	0.725088173625904
GO:0045309	protein phosphorylated amino acid binding	3/599	59/18639	0.0508474576271186	1.58221329334201	0.294674308379386	0.725088173625904
GO:0016247	channel regulator activity	7/599	168/18639	0.0416666666666667	1.29653589315526	0.296165542950084	0.725088173625904
GO:0015035	protein-disulfide reductase activity	2/599	34/18639	0.0588235294117647	1.83040361386625	0.298830074270427	0.725088173625904
GO:0051427	hormone receptor binding	2/599	34/18639	0.0588235294117647	1.83040361386625	0.298830074270427	0.725088173625904
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	4/599	86/18639	0.0465116279069767	1.44729588073145	0.298989454956396	0.725088173625904
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0002162	dystroglycan binding	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0008271	secondary active sulfate transmembrane transporter activity	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0008432	JUN kinase binding	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0008526	phosphatidylinositol transfer activity	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0010854	adenylate cyclase regulator activity	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0015217	ADP transmembrane transporter activity	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0032794	GTPase activating protein binding	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0034713	type I transforming growth factor beta receptor binding	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0043522	leucine zipper domain binding	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0048185	activin binding	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0050998	nitric-oxide synthase binding	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0097493	structural molecule activity conferring elasticity	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0140537	transcription regulator activator activity	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/599	11/18639	0.0909090909090909	2.82880558506602	0.301911303607086	0.725088173625904
GO:0098531	ligand-modulated transcription factor activity	3/599	60/18639	0.05	1.55584307178631	0.303511240252628	0.725088173625904
GO:0019887	protein kinase regulator activity	10/599	255/18639	0.0392156862745098	1.22026907591083	0.305397114633263	0.725088173625904
GO:0020037	heme binding	6/599	142/18639	0.0422535211267606	1.31479696207294	0.306376981512016	0.725088173625904
GO:0141108	transporter regulator activity	7/599	170/18639	0.0411764705882353	1.28128252970637	0.306389287429415	0.725088173625904
GO:0035091	phosphatidylinositol binding	11/599	284/18639	0.0387323943661972	1.20523054856686	0.306569219607139	0.725088173625904
GO:0003713	transcription coactivator activity	10/599	256/18639	0.0390625	1.21550239983306	0.309563884296804	0.725088173625904
GO:0016229	steroid dehydrogenase activity	2/599	35/18639	0.0571428571428571	1.77810636775578	0.310791274917595	0.725088173625904
GO:0015026	coreceptor activity	3/599	61/18639	0.0491803278688525	1.53033744765867	0.312359636711173	0.725088173625904
GO:0019903	protein phosphatase binding	6/599	144/18639	0.0416666666666667	1.29653589315526	0.317674614301102	0.725088173625904
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	4/599	89/18639	0.0449438202247191	1.39851062632477	0.320849853983051	0.725088173625904
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	4/599	89/18639	0.0449438202247191	1.39851062632477	0.320849853983051	0.725088173625904
GO:0003995	acyl-CoA dehydrogenase activity	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0005078	MAP-kinase scaffold activity	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0005095	GTPase inhibitor activity	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0005165	neurotrophin receptor binding	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0005527	macrolide binding	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0015132	prostaglandin transmembrane transporter activity	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0016208	AMP binding	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0017166	vinculin binding	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0034452	dynactin binding	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0070679	inositol 1,4,5 trisphosphate binding	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0097677	STAT family protein binding	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/599	12/18639	0.0833333333333333	2.59307178631052	0.324358969977032	0.725088173625904
GO:0003823	antigen binding	7/599	174/18639	0.0402298850574713	1.25182775890853	0.327034776201568	0.72914085986893
GO:0140793	histone H2AXY142 phosphatase activity	4/599	90/18639	0.0444444444444444	1.38297161936561	0.328165187591904	0.729735746092524
GO:0042805	actinin binding	2/599	37/18639	0.0540540540540541	1.68199251003925	0.334574150503913	0.733556077334697
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0005172	vascular endothelial growth factor receptor binding	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0005542	folic acid binding	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0008035	high-density lipoprotein particle binding	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0008253	5'-nucleotidase activity	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0017154	semaphorin receptor activity	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0019855	calcium channel inhibitor activity	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0032396	inhibitory MHC class I receptor activity	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0035673	oligopeptide transmembrane transporter activity	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0043560	insulin receptor substrate binding	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0046974	histone H3K9 methyltransferase activity	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0046975	histone H3K36 methyltransferase activity	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0071714	icosanoid transmembrane transporter activity	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/599	13/18639	0.0769230769230769	2.39360472582509	0.346085977921615	0.733556077334697
GO:0005501	retinoid binding	2/599	38/18639	0.0526315789473684	1.63772954924875	0.346377366694135	0.733556077334697
GO:0019840	isoprenoid binding	2/599	38/18639	0.0526315789473684	1.63772954924875	0.346377366694135	0.733556077334697
GO:0051219	phosphoprotein binding	4/599	93/18639	0.043010752688172	1.33835963164414	0.350157161868822	0.739707004447886
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/599	39/18639	0.0512820512820513	1.5957364838834	0.358110525421394	0.74570320898801
GO:0016853	isomerase activity	7/599	180/18639	0.0388888888888889	1.21010016694491	0.358372597115105	0.74570320898801
GO:0008094	ATP-dependent activity, acting on DNA	8/599	210/18639	0.0380952380952381	1.18540424517052	0.363035426297352	0.74570320898801
GO:0046906	tetrapyrrole binding	6/599	152/18639	0.0394736842105263	1.22829716193656	0.363379651932092	0.74570320898801
GO:0016500	protein-hormone receptor activity	3/599	67/18639	0.0447761194029851	1.39329230309222	0.365421138806455	0.74570320898801
GO:0005344	oxygen carrier activity	1/599	14/18639	0.0714285714285714	2.22263295969473	0.367115425963328	0.74570320898801
GO:0005347	ATP transmembrane transporter activity	1/599	14/18639	0.0714285714285714	2.22263295969473	0.367115425963328	0.74570320898801
GO:0008494	translation activator activity	1/599	14/18639	0.0714285714285714	2.22263295969473	0.367115425963328	0.74570320898801
GO:0019992	diacylglycerol binding	1/599	14/18639	0.0714285714285714	2.22263295969473	0.367115425963328	0.74570320898801
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/599	14/18639	0.0714285714285714	2.22263295969473	0.367115425963328	0.74570320898801
GO:0031404	chloride ion binding	1/599	14/18639	0.0714285714285714	2.22263295969473	0.367115425963328	0.74570320898801
GO:0043176	amine binding	1/599	14/18639	0.0714285714285714	2.22263295969473	0.367115425963328	0.74570320898801
GO:0061783	peptidoglycan muralytic activity	1/599	14/18639	0.0714285714285714	2.22263295969473	0.367115425963328	0.74570320898801
GO:0071933	Arp2/3 complex binding	1/599	14/18639	0.0714285714285714	2.22263295969473	0.367115425963328	0.74570320898801
GO:1901474	azole transmembrane transporter activity	1/599	14/18639	0.0714285714285714	2.22263295969473	0.367115425963328	0.74570320898801
GO:1901612	cardiolipin binding	1/599	14/18639	0.0714285714285714	2.22263295969473	0.367115425963328	0.74570320898801
GO:0004386	helicase activity	6/599	155/18639	0.0387096774193548	1.20452366847972	0.380635608583782	0.754405239824407
GO:0001530	lipopolysaccharide binding	2/599	41/18639	0.0487804878048781	1.51789567979152	0.38133650615534	0.754405239824407
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	2/599	41/18639	0.0487804878048781	1.51789567979152	0.38133650615534	0.754405239824407
GO:0017080	sodium channel regulator activity	2/599	41/18639	0.0487804878048781	1.51789567979152	0.38133650615534	0.754405239824407
GO:0002039	p53 binding	3/599	69/18639	0.0434782608695652	1.35290701894462	0.382990934943635	0.754405239824407
GO:0004725	protein tyrosine phosphatase activity	4/599	98/18639	0.0408163265306122	1.27007597696842	0.386803554370023	0.754405239824407
GO:0042626	ATPase-coupled transmembrane transporter activity	4/599	98/18639	0.0408163265306122	1.27007597696842	0.386803554370023	0.754405239824407
GO:0008252	nucleotidase activity	1/599	15/18639	0.0666666666666667	2.07445742904841	0.387469673471944	0.754405239824407
GO:0010181	FMN binding	1/599	15/18639	0.0666666666666667	2.07445742904841	0.387469673471944	0.754405239824407
GO:0015116	sulfate transmembrane transporter activity	1/599	15/18639	0.0666666666666667	2.07445742904841	0.387469673471944	0.754405239824407
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/599	15/18639	0.0666666666666667	2.07445742904841	0.387469673471944	0.754405239824407
GO:0015929	hexosaminidase activity	1/599	15/18639	0.0666666666666667	2.07445742904841	0.387469673471944	0.754405239824407
GO:0016846	carbon-sulfur lyase activity	1/599	15/18639	0.0666666666666667	2.07445742904841	0.387469673471944	0.754405239824407
GO:0017081	chloride channel regulator activity	1/599	15/18639	0.0666666666666667	2.07445742904841	0.387469673471944	0.754405239824407
GO:0061578	K63-linked deubiquitinase activity	1/599	15/18639	0.0666666666666667	2.07445742904841	0.387469673471944	0.754405239824407
GO:0120283	protein serine/threonine kinase binding	1/599	15/18639	0.0666666666666667	2.07445742904841	0.387469673471944	0.754405239824407
GO:0141050	histone H3K deacetylase activity	1/599	15/18639	0.0666666666666667	2.07445742904841	0.387469673471944	0.754405239824407
GO:0141051	histone H4K deacetylase activity	1/599	15/18639	0.0666666666666667	2.07445742904841	0.387469673471944	0.754405239824407
GO:0140597	protein carrier chaperone	7/599	188/18639	0.0372340425531915	1.15860654281959	0.400504243084475	0.767988745124423
GO:0043130	ubiquitin binding	4/599	100/18639	0.04	1.24467445742905	0.401401065361146	0.767988745124423
GO:0140297	DNA-binding transcription factor binding	17/599	488/18639	0.0348360655737705	1.08398902542489	0.401600723776045	0.767988745124423
GO:0048156	tau protein binding	2/599	43/18639	0.0465116279069767	1.44729588073145	0.404197239877113	0.767988745124423
GO:0030695	GTPase regulator activity	17/599	489/18639	0.0347648261758691	1.08177227895163	0.404874113311751	0.767988745124423
GO:0005024	transforming growth factor beta receptor activity	1/599	16/18639	0.0625	1.94480383973289	0.407170364278984	0.767988745124423
GO:0005149	interleukin-1 receptor binding	1/599	16/18639	0.0625	1.94480383973289	0.407170364278984	0.767988745124423
GO:0008142	oxysterol binding	1/599	16/18639	0.0625	1.94480383973289	0.407170364278984	0.767988745124423
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/599	16/18639	0.0625	1.94480383973289	0.407170364278984	0.767988745124423
GO:0016722	oxidoreductase activity, acting on metal ions	1/599	16/18639	0.0625	1.94480383973289	0.407170364278984	0.767988745124423
GO:0022841	potassium ion leak channel activity	1/599	16/18639	0.0625	1.94480383973289	0.407170364278984	0.767988745124423
GO:0030275	LRR domain binding	1/599	16/18639	0.0625	1.94480383973289	0.407170364278984	0.767988745124423
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/599	16/18639	0.0625	1.94480383973289	0.407170364278984	0.767988745124423
GO:0043023	ribosomal large subunit binding	1/599	16/18639	0.0625	1.94480383973289	0.407170364278984	0.767988745124423
GO:0060589	nucleoside-triphosphatase regulator activity	17/599	490/18639	0.0346938775510204	1.07956458042315	0.408149715114982	0.768121401497015
GO:0019902	phosphatase binding	7/599	190/18639	0.0368421052631579	1.14641068447412	0.41104699106505	0.771854905444371
GO:0001046	core promoter sequence-specific DNA binding	2/599	44/18639	0.0454545454545455	1.41440279253301	0.415475750347817	0.776719046557312
GO:0019205	nucleobase-containing compound kinase activity	2/599	44/18639	0.0454545454545455	1.41440279253301	0.415475750347817	0.776719046557312
GO:0043539	protein serine/threonine kinase activator activity	3/599	73/18639	0.0410958904109589	1.2787751274956	0.417765329165087	0.779275282879687
GO:0005179	hormone activity	5/599	132/18639	0.0378787878787879	1.17866899377751	0.419247801404987	0.780318044465229
GO:0004550	nucleoside diphosphate kinase activity	1/599	17/18639	0.0588235294117647	1.83040361386625	0.426238449538979	0.78033743520075
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/599	17/18639	0.0588235294117647	1.83040361386625	0.426238449538979	0.78033743520075
GO:0015278	intracellularly gated calcium channel activity	1/599	17/18639	0.0588235294117647	1.83040361386625	0.426238449538979	0.78033743520075
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/599	17/18639	0.0588235294117647	1.83040361386625	0.426238449538979	0.78033743520075
GO:0070492	oligosaccharide binding	1/599	17/18639	0.0588235294117647	1.83040361386625	0.426238449538979	0.78033743520075
GO:0031491	nucleosome binding	3/599	74/18639	0.0405405405405405	1.26149438252944	0.42636266036201	0.78033743520075
GO:0035064	methylated histone binding	3/599	74/18639	0.0405405405405405	1.26149438252944	0.42636266036201	0.78033743520075
GO:0046915	transition metal ion transmembrane transporter activity	2/599	45/18639	0.0444444444444444	1.38297161936561	0.426646029660055	0.78033743520075
GO:0003725	double-stranded RNA binding	3/599	75/18639	0.04	1.24467445742905	0.434915135806048	0.786698317657195
GO:0019003	GDP binding	3/599	75/18639	0.04	1.24467445742905	0.434915135806048	0.786698317657195
GO:0030276	clathrin binding	2/599	46/18639	0.0434782608695652	1.35290701894462	0.437703382294831	0.786698317657195
GO:0140034	methylation-dependent protein binding	3/599	76/18639	0.0394736842105263	1.22829716193656	0.443419824442166	0.786698317657195
GO:0000400	four-way junction DNA binding	1/599	18/18639	0.0555555555555556	1.72871452420701	0.444694209861509	0.786698317657195
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/599	18/18639	0.0555555555555556	1.72871452420701	0.444694209861509	0.786698317657195
GO:0004706	JUN kinase kinase kinase activity	1/599	18/18639	0.0555555555555556	1.72871452420701	0.444694209861509	0.786698317657195
GO:0008409	5'-3' exonuclease activity	1/599	18/18639	0.0555555555555556	1.72871452420701	0.444694209861509	0.786698317657195
GO:0008525	phosphatidylcholine transporter activity	1/599	18/18639	0.0555555555555556	1.72871452420701	0.444694209861509	0.786698317657195
GO:0015172	acidic amino acid transmembrane transporter activity	1/599	18/18639	0.0555555555555556	1.72871452420701	0.444694209861509	0.786698317657195
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/599	18/18639	0.0555555555555556	1.72871452420701	0.444694209861509	0.786698317657195
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/599	18/18639	0.0555555555555556	1.72871452420701	0.444694209861509	0.786698317657195
GO:0032393	MHC class I receptor activity	1/599	18/18639	0.0555555555555556	1.72871452420701	0.444694209861509	0.786698317657195
GO:0034185	apolipoprotein binding	1/599	18/18639	0.0555555555555556	1.72871452420701	0.444694209861509	0.786698317657195
GO:0070064	proline-rich region binding	1/599	18/18639	0.0555555555555556	1.72871452420701	0.444694209861509	0.786698317657195
GO:0004843	cysteine-type deubiquitinase activity	4/599	108/18639	0.037037037037037	1.15247634947134	0.458993044605908	0.786698317657195
GO:0016879	ligase activity, forming carbon-nitrogen bonds	2/599	48/18639	0.0416666666666667	1.29653589315526	0.459462565983245	0.786698317657195
GO:0038187	pattern recognition receptor activity	2/599	48/18639	0.0416666666666667	1.29653589315526	0.459462565983245	0.786698317657195
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/599	19/18639	0.0526315789473684	1.63772954924875	0.462557276737238	0.786698317657195
GO:0008301	DNA binding, bending	1/599	19/18639	0.0526315789473684	1.63772954924875	0.462557276737238	0.786698317657195
GO:0022840	leak channel activity	1/599	19/18639	0.0526315789473684	1.63772954924875	0.462557276737238	0.786698317657195
GO:0022842	narrow pore channel activity	1/599	19/18639	0.0526315789473684	1.63772954924875	0.462557276737238	0.786698317657195
GO:0034987	immunoglobulin receptor binding	1/599	19/18639	0.0526315789473684	1.63772954924875	0.462557276737238	0.786698317657195
GO:0042800	histone H3K4 methyltransferase activity	1/599	19/18639	0.0526315789473684	1.63772954924875	0.462557276737238	0.786698317657195
GO:0046624	sphingolipid transporter activity	1/599	19/18639	0.0526315789473684	1.63772954924875	0.462557276737238	0.786698317657195
GO:0050145	nucleoside monophosphate kinase activity	1/599	19/18639	0.0526315789473684	1.63772954924875	0.462557276737238	0.786698317657195
GO:0070003	threonine-type peptidase activity	1/599	19/18639	0.0526315789473684	1.63772954924875	0.462557276737238	0.786698317657195
GO:0097001	ceramide binding	1/599	19/18639	0.0526315789473684	1.63772954924875	0.462557276737238	0.786698317657195
GO:0140036	ubiquitin-modified protein reader activity	1/599	19/18639	0.0526315789473684	1.63772954924875	0.462557276737238	0.786698317657195
GO:0004620	phospholipase activity	4/599	109/18639	0.036697247706422	1.14190317195326	0.466069186021042	0.786698317657195
GO:0004713	protein tyrosine kinase activity	5/599	140/18639	0.0357142857142857	1.11131647984736	0.469622518174371	0.786698317657195
GO:0005004	GPI-linked ephrin receptor activity	2/599	49/18639	0.0408163265306122	1.27007597696842	0.470156982741874	0.786698317657195
GO:0005008	hepatocyte growth factor receptor activity	2/599	49/18639	0.0408163265306122	1.27007597696842	0.470156982741874	0.786698317657195
GO:0005009	insulin receptor activity	2/599	49/18639	0.0408163265306122	1.27007597696842	0.470156982741874	0.786698317657195
GO:0005011	macrophage colony-stimulating factor receptor activity	2/599	49/18639	0.0408163265306122	1.27007597696842	0.470156982741874	0.786698317657195
GO:0005018	platelet-derived growth factor alpha-receptor activity	2/599	49/18639	0.0408163265306122	1.27007597696842	0.470156982741874	0.786698317657195
GO:0005020	stem cell factor receptor activity	2/599	49/18639	0.0408163265306122	1.27007597696842	0.470156982741874	0.786698317657195
GO:0008288	boss receptor activity	2/599	49/18639	0.0408163265306122	1.27007597696842	0.470156982741874	0.786698317657195
GO:0016763	pentosyltransferase activity	2/599	49/18639	0.0408163265306122	1.27007597696842	0.470156982741874	0.786698317657195
GO:0035254	glutamate receptor binding	2/599	49/18639	0.0408163265306122	1.27007597696842	0.470156982741874	0.786698317657195
GO:0036332	placental growth factor receptor activity	2/599	49/18639	0.0408163265306122	1.27007597696842	0.470156982741874	0.786698317657195
GO:0038062	protein tyrosine kinase collagen receptor activity	2/599	49/18639	0.0408163265306122	1.27007597696842	0.470156982741874	0.786698317657195
GO:0060175	brain-derived neurotrophic factor receptor activity	2/599	49/18639	0.0408163265306122	1.27007597696842	0.470156982741874	0.786698317657195
GO:0001972	retinoic acid binding	1/599	20/18639	0.05	1.55584307178631	0.479846653280439	0.788760087960412
GO:0010851	cyclase regulator activity	1/599	20/18639	0.05	1.55584307178631	0.479846653280439	0.788760087960412
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/599	20/18639	0.05	1.55584307178631	0.479846653280439	0.788760087960412
GO:0042288	MHC class I protein binding	1/599	20/18639	0.05	1.55584307178631	0.479846653280439	0.788760087960412
GO:0043024	ribosomal small subunit binding	1/599	20/18639	0.05	1.55584307178631	0.479846653280439	0.788760087960412
GO:0005125	cytokine activity	8/599	234/18639	0.0341880341880342	1.06382432258893	0.479992949052829	0.788760087960412
GO:1902936	phosphatidylinositol bisphosphate binding	4/599	111/18639	0.036036036036036	1.12132834002617	0.48011967665062	0.788760087960412
GO:0005007	fibroblast growth factor receptor activity	2/599	50/18639	0.04	1.24467445742905	0.480723603904866	0.788760087960412
GO:0005017	platelet-derived growth factor receptor activity	2/599	50/18639	0.04	1.24467445742905	0.480723603904866	0.788760087960412
GO:0005019	platelet-derived growth factor beta-receptor activity	2/599	50/18639	0.04	1.24467445742905	0.480723603904866	0.788760087960412
GO:0030971	receptor tyrosine kinase binding	3/599	81/18639	0.037037037037037	1.15247634947134	0.485133210485809	0.794452641202536
GO:0005010	insulin-like growth factor receptor activity	2/599	51/18639	0.0392156862745098	1.22026907591083	0.491159589635103	0.797739012341732
GO:0005030	neurotrophin receptor activity	2/599	51/18639	0.0392156862745098	1.22026907591083	0.491159589635103	0.797739012341732
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/599	21/18639	0.0476190476190476	1.48175530646315	0.496580734309764	0.797739012341732
GO:0005123	death receptor binding	1/599	21/18639	0.0476190476190476	1.48175530646315	0.496580734309764	0.797739012341732
GO:0010314	phosphatidylinositol-5-phosphate binding	1/599	21/18639	0.0476190476190476	1.48175530646315	0.496580734309764	0.797739012341732
GO:0015125	bile acid transmembrane transporter activity	1/599	21/18639	0.0476190476190476	1.48175530646315	0.496580734309764	0.797739012341732
GO:0035613	RNA stem-loop binding	1/599	21/18639	0.0476190476190476	1.48175530646315	0.496580734309764	0.797739012341732
GO:0051010	microtubule plus-end binding	1/599	21/18639	0.0476190476190476	1.48175530646315	0.496580734309764	0.797739012341732
GO:0070182	DNA polymerase binding	1/599	21/18639	0.0476190476190476	1.48175530646315	0.496580734309764	0.797739012341732
GO:0072542	protein phosphatase activator activity	1/599	21/18639	0.0476190476190476	1.48175530646315	0.496580734309764	0.797739012341732
GO:0101005	deubiquitinase activity	4/599	115/18639	0.0347826086956522	1.08232561515569	0.507769120330083	0.800918373920817
GO:0004860	protein kinase inhibitor activity	3/599	84/18639	0.0357142857142857	1.11131647984736	0.509428760288359	0.800918373920817
GO:0051117	ATPase binding	3/599	84/18639	0.0357142857142857	1.11131647984736	0.509428760288359	0.800918373920817
GO:0005003	ephrin receptor activity	2/599	53/18639	0.0377358490566038	1.17422118625382	0.511629846823489	0.800918373920817
GO:0005005	transmembrane-ephrin receptor activity	2/599	53/18639	0.0377358490566038	1.17422118625382	0.511629846823489	0.800918373920817
GO:0038064	collagen receptor activity	2/599	53/18639	0.0377358490566038	1.17422118625382	0.511629846823489	0.800918373920817
GO:0004407	histone deacetylase activity	1/599	22/18639	0.0454545454545455	1.41440279253301	0.512777325788358	0.800918373920817
GO:0008093	cytoskeletal anchor activity	1/599	22/18639	0.0454545454545455	1.41440279253301	0.512777325788358	0.800918373920817
GO:0008970	phospholipase A1 activity	1/599	22/18639	0.0454545454545455	1.41440279253301	0.512777325788358	0.800918373920817
GO:0016881	acid-amino acid ligase activity	1/599	22/18639	0.0454545454545455	1.41440279253301	0.512777325788358	0.800918373920817
GO:0033558	protein lysine deacetylase activity	1/599	22/18639	0.0454545454545455	1.41440279253301	0.512777325788358	0.800918373920817
GO:0061133	endopeptidase activator activity	1/599	22/18639	0.0454545454545455	1.41440279253301	0.512777325788358	0.800918373920817
GO:0070034	telomerase RNA binding	1/599	22/18639	0.0454545454545455	1.41440279253301	0.512777325788358	0.800918373920817
GO:0140035	ubiquitin-like protein reader activity	1/599	22/18639	0.0454545454545455	1.41440279253301	0.512777325788358	0.800918373920817
GO:0140517	protein-RNA adaptor activity	1/599	22/18639	0.0454545454545455	1.41440279253301	0.512777325788358	0.800918373920817
GO:0019208	phosphatase regulator activity	4/599	117/18639	0.0341880341880342	1.06382432258893	0.521344810671822	0.811300856386169
GO:1990782	protein tyrosine kinase binding	4/599	117/18639	0.0341880341880342	1.06382432258893	0.521344810671822	0.811300856386169
GO:0000295	adenine nucleotide transmembrane transporter activity	1/599	23/18639	0.0434782608695652	1.35290701894462	0.528453663643693	0.814860120034527
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/599	23/18639	0.0434782608695652	1.35290701894462	0.528453663643693	0.814860120034527
GO:0016493	C-C chemokine receptor activity	1/599	23/18639	0.0434782608695652	1.35290701894462	0.528453663643693	0.814860120034527
GO:0043274	phospholipase binding	1/599	23/18639	0.0434782608695652	1.35290701894462	0.528453663643693	0.814860120034527
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/599	23/18639	0.0434782608695652	1.35290701894462	0.528453663643693	0.814860120034527
GO:0008017	microtubule binding	9/599	276/18639	0.0326086956521739	1.01468026420846	0.529821041626603	0.815480473906156
GO:0008081	phosphoric diester hydrolase activity	3/599	87/18639	0.0344827586206897	1.07299522192159	0.533109477770241	0.819050015847007
GO:0001217	DNA-binding transcription repressor activity	9/599	278/18639	0.0323741007194245	1.00738040619258	0.538571738347216	0.819972736671758
GO:0032182	ubiquitin-like protein binding	4/599	120/18639	0.0333333333333333	1.03722871452421	0.541367848075164	0.819972736671758
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/599	24/18639	0.0416666666666667	1.29653589315526	0.543626431986915	0.819972736671758
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/599	24/18639	0.0416666666666667	1.29653589315526	0.543626431986915	0.819972736671758
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/599	24/18639	0.0416666666666667	1.29653589315526	0.543626431986915	0.819972736671758
GO:0005315	phosphate transmembrane transporter activity	1/599	24/18639	0.0416666666666667	1.29653589315526	0.543626431986915	0.819972736671758
GO:0019957	C-C chemokine binding	1/599	24/18639	0.0416666666666667	1.29653589315526	0.543626431986915	0.819972736671758
GO:0030215	semaphorin receptor binding	1/599	24/18639	0.0416666666666667	1.29653589315526	0.543626431986915	0.819972736671758
GO:0050431	transforming growth factor beta binding	1/599	24/18639	0.0416666666666667	1.29653589315526	0.543626431986915	0.819972736671758
GO:0070300	phosphatidic acid binding	1/599	24/18639	0.0416666666666667	1.29653589315526	0.543626431986915	0.819972736671758
GO:0030246	carbohydrate binding	9/599	280/18639	0.0321428571428571	1.00018483186263	0.547262063355897	0.819972736671758
GO:1901981	phosphatidylinositol phosphate binding	6/599	185/18639	0.0324324324324324	1.00919550602355	0.548756652457491	0.819972736671758
GO:0019210	kinase inhibitor activity	3/599	90/18639	0.0333333333333333	1.03722871452421	0.55613238201452	0.819972736671758
GO:0004709	MAP kinase kinase kinase activity	1/599	25/18639	0.04	1.24467445742905	0.558311780750807	0.819972736671758
GO:0005537	D-mannose binding	1/599	25/18639	0.04	1.24467445742905	0.558311780750807	0.819972736671758
GO:0015271	outward rectifier potassium channel activity	1/599	25/18639	0.04	1.24467445742905	0.558311780750807	0.819972736671758
GO:0015645	fatty acid ligase activity	1/599	25/18639	0.04	1.24467445742905	0.558311780750807	0.819972736671758
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/599	25/18639	0.04	1.24467445742905	0.558311780750807	0.819972736671758
GO:0019211	phosphatase activator activity	1/599	25/18639	0.04	1.24467445742905	0.558311780750807	0.819972736671758
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/599	25/18639	0.04	1.24467445742905	0.558311780750807	0.819972736671758
GO:0019707	protein-cysteine S-acyltransferase activity	1/599	25/18639	0.04	1.24467445742905	0.558311780750807	0.819972736671758
GO:0120515	fatty acid-CoA ligase activity	1/599	25/18639	0.04	1.24467445742905	0.558311780750807	0.819972736671758
GO:0072341	modified amino acid binding	3/599	91/18639	0.032967032967033	1.02583059678218	0.563654280477809	0.819972736671758
GO:0001786	phosphatidylserine binding	2/599	59/18639	0.0338983050847458	1.05480886222801	0.56969975930878	0.819972736671758
GO:0015459	potassium channel regulator activity	2/599	59/18639	0.0338983050847458	1.05480886222801	0.56969975930878	0.819972736671758
GO:0031593	polyubiquitin modification-dependent protein binding	2/599	59/18639	0.0338983050847458	1.05480886222801	0.56969975930878	0.819972736671758
GO:0043178	alcohol binding	3/599	92/18639	0.0326086956521739	1.01468026420846	0.571098078912953	0.819972736671758
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/599	26/18639	0.0384615384615385	1.19680236291255	0.572525342764896	0.819972736671758
GO:0004435	phosphatidylinositol phospholipase C activity	1/599	26/18639	0.0384615384615385	1.19680236291255	0.572525342764896	0.819972736671758
GO:0004529	DNA exonuclease activity	1/599	26/18639	0.0384615384615385	1.19680236291255	0.572525342764896	0.819972736671758
GO:0005160	transforming growth factor beta receptor binding	1/599	26/18639	0.0384615384615385	1.19680236291255	0.572525342764896	0.819972736671758
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	1/599	26/18639	0.0384615384615385	1.19680236291255	0.572525342764896	0.819972736671758
GO:0015216	purine nucleotide transmembrane transporter activity	1/599	26/18639	0.0384615384615385	1.19680236291255	0.572525342764896	0.819972736671758
GO:0030507	spectrin binding	1/599	26/18639	0.0384615384615385	1.19680236291255	0.572525342764896	0.819972736671758
GO:0034237	protein kinase A regulatory subunit binding	1/599	26/18639	0.0384615384615385	1.19680236291255	0.572525342764896	0.819972736671758
GO:0050681	nuclear androgen receptor binding	1/599	26/18639	0.0384615384615385	1.19680236291255	0.572525342764896	0.819972736671758
GO:0051139	metal cation:proton antiporter activity	1/599	26/18639	0.0384615384615385	1.19680236291255	0.572525342764896	0.819972736671758
GO:0052742	phosphatidylinositol kinase activity	1/599	26/18639	0.0384615384615385	1.19680236291255	0.572525342764896	0.819972736671758
GO:0070006	metalloaminopeptidase activity	1/599	26/18639	0.0384615384615385	1.19680236291255	0.572525342764896	0.819972736671758
GO:0070412	R-SMAD binding	1/599	26/18639	0.0384615384615385	1.19680236291255	0.572525342764896	0.819972736671758
GO:0051213	dioxygenase activity	3/599	93/18639	0.032258064516129	1.0037697237331	0.578462776147756	0.826271079943156
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	2/599	60/18639	0.0333333333333333	1.03722871452421	0.578878673758992	0.826271079943156
GO:0008266	poly(U) RNA binding	1/599	27/18639	0.037037037037037	1.15247634947134	0.586282250285652	0.831315262270586
GO:0016405	CoA-ligase activity	1/599	27/18639	0.037037037037037	1.15247634947134	0.586282250285652	0.831315262270586
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/599	27/18639	0.037037037037037	1.15247634947134	0.586282250285652	0.831315262270586
GO:0019783	ubiquitin-like protein peptidase activity	4/599	127/18639	0.031496062992126	0.980058627896888	0.586347806287892	0.831315262270586
GO:0019905	syntaxin binding	2/599	61/18639	0.0327868852459016	1.02022496510578	0.587913217387732	0.832138473521999
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	4/599	128/18639	0.03125	0.972401919866444	0.592561181872214	0.837314713515085
GO:0035591	signaling adaptor activity	4/599	129/18639	0.0310077519379845	0.964863920487634	0.598719168423775	0.84023149683955
GO:0005242	inward rectifier potassium channel activity	1/599	28/18639	0.0357142857142857	1.11131647984736	0.599597150999111	0.84023149683955
GO:0019789	SUMO transferase activity	1/599	28/18639	0.0357142857142857	1.11131647984736	0.599597150999111	0.84023149683955
GO:0045499	chemorepellent activity	1/599	28/18639	0.0357142857142857	1.11131647984736	0.599597150999111	0.84023149683955
GO:0046875	ephrin receptor binding	1/599	28/18639	0.0357142857142857	1.11131647984736	0.599597150999111	0.84023149683955
GO:0016298	lipase activity	4/599	130/18639	0.0307692307692308	0.957441890330037	0.604821113511453	0.845766078058636
GO:1901682	sulfur compound transmembrane transporter activity	2/599	63/18639	0.0317460317460317	0.987836870975435	0.605548493757958	0.845766078058636
GO:0031072	heat shock protein binding	4/599	131/18639	0.0305343511450382	0.950133173609961	0.610866409100399	0.847052649538924
GO:0000287	magnesium ion binding	7/599	230/18639	0.0304347826086957	0.947034913261232	0.611229298215165	0.847052649538924
GO:0005085	guanyl-nucleotide exchange factor activity	7/599	230/18639	0.0304347826086957	0.947034913261232	0.611229298215165	0.847052649538924
GO:0004629	phospholipase C activity	1/599	29/18639	0.0344827586206897	1.07299522192159	0.612484223512761	0.847052649538924
GO:0016417	S-acyltransferase activity	1/599	29/18639	0.0344827586206897	1.07299522192159	0.612484223512761	0.847052649538924
GO:0099604	ligand-gated calcium channel activity	1/599	29/18639	0.0344827586206897	1.07299522192159	0.612484223512761	0.847052649538924
GO:0004536	DNA nuclease activity	2/599	64/18639	0.03125	0.972401919866444	0.614149273726476	0.847967542972013
GO:0001664	G protein-coupled receptor binding	9/599	297/18639	0.0303030303030303	0.942935195022007	0.618261147559506	0.852252315967019
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/599	30/18639	0.0333333333333333	1.03722871452421	0.624957192352946	0.854512665919481
GO:0008187	poly-pyrimidine tract binding	1/599	30/18639	0.0333333333333333	1.03722871452421	0.624957192352946	0.854512665919481
GO:0015215	nucleotide transmembrane transporter activity	1/599	30/18639	0.0333333333333333	1.03722871452421	0.624957192352946	0.854512665919481
GO:0016769	transferase activity, transferring nitrogenous groups	1/599	30/18639	0.0333333333333333	1.03722871452421	0.624957192352946	0.854512665919481
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/599	30/18639	0.0333333333333333	1.03722871452421	0.624957192352946	0.854512665919481
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	8/599	268/18639	0.0298507462686567	0.928861535394812	0.633662429814396	0.863248717622471
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/599	31/18639	0.032258064516129	1.0037697237331	0.63702934248356	0.863248717622471
GO:0016878	acid-thiol ligase activity	1/599	31/18639	0.032258064516129	1.0037697237331	0.63702934248356	0.863248717622471
GO:0047499	calcium-independent phospholipase A2 activity	1/599	31/18639	0.032258064516129	1.0037697237331	0.63702934248356	0.863248717622471
GO:0070273	phosphatidylinositol-4-phosphate binding	1/599	31/18639	0.032258064516129	1.0037697237331	0.63702934248356	0.863248717622471
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	2/599	67/18639	0.0298507462686567	0.928861535394812	0.639087464971211	0.863248717622471
GO:0140789	histone phosphatase activity	4/599	136/18639	0.0294117647058824	0.915201806933124	0.640224849576077	0.863248717622471
GO:0140097	catalytic activity, acting on DNA	10/599	336/18639	0.0297619047619048	0.92609706653947	0.642315882102178	0.863248717622471
GO:0016922	nuclear receptor binding	4/599	137/18639	0.0291970802919708	0.908521501773028	0.6459198439655	0.863248717622471
GO:0005096	GTPase activator activity	8/599	271/18639	0.029520295202952	0.918578935371991	0.645987874379379	0.863248717622471
GO:0005548	phospholipid transporter activity	2/599	68/18639	0.0294117647058824	0.915201806933124	0.647113806699083	0.863248717622471
GO:0032934	sterol binding	2/599	68/18639	0.0294117647058824	0.915201806933124	0.647113806699083	0.863248717622471
GO:0140223	general transcription initiation factor activity	2/599	68/18639	0.0294117647058824	0.915201806933124	0.647113806699083	0.863248717622471
GO:1990841	promoter-specific chromatin binding	2/599	68/18639	0.0294117647058824	0.915201806933124	0.647113806699083	0.863248717622471
GO:0047498	calcium-dependent phospholipase A2 activity	1/599	32/18639	0.03125	0.972401919866444	0.648713533361265	0.863248717622471
GO:0051059	NF-kappaB binding	1/599	32/18639	0.03125	0.972401919866444	0.648713533361265	0.863248717622471
GO:0070717	poly-purine tract binding	1/599	32/18639	0.03125	0.972401919866444	0.648713533361265	0.863248717622471
GO:0008080	N-acetyltransferase activity	2/599	69/18639	0.0289855072463768	0.901938012629745	0.654998071527604	0.870241148491864
GO:0019956	chemokine binding	1/599	33/18639	0.0303030303030303	0.942935195022007	0.660022212542036	0.871435577496907
GO:0030296	protein tyrosine kinase activator activity	1/599	33/18639	0.0303030303030303	0.942935195022007	0.660022212542036	0.871435577496907
GO:0071889	14-3-3 protein binding	1/599	33/18639	0.0303030303030303	0.942935195022007	0.660022212542036	0.871435577496907
GO:0140416	transcription regulator inhibitor activity	1/599	33/18639	0.0303030303030303	0.942935195022007	0.660022212542036	0.871435577496907
GO:0004721	phosphoprotein phosphatase activity	5/599	175/18639	0.0285714285714286	0.889053183877892	0.666609699391628	0.87876005614029
GO:0140299	molecular sensor activity	2/599	71/18639	0.028169014084507	0.876531308048626	0.67034376888444	0.8790193447768
GO:0019825	oxygen binding	1/599	34/18639	0.0294117647058824	0.915201806933124	0.670967428853297	0.8790193447768
GO:0030332	cyclin binding	1/599	34/18639	0.0294117647058824	0.915201806933124	0.670967428853297	0.8790193447768
GO:0090482	vitamin transmembrane transporter activity	1/599	34/18639	0.0294117647058824	0.915201806933124	0.670967428853297	0.8790193447768
GO:0005496	steroid binding	3/599	108/18639	0.0277777777777778	0.864357262103506	0.679006428102292	0.887394320721059
GO:0005319	lipid transporter activity	5/599	178/18639	0.0280898876404494	0.874069141452983	0.68108793992056	0.887394320721059
GO:0004623	phospholipase A2 activity	1/599	35/18639	0.0285714285714286	0.889053183877892	0.681560845145524	0.887394320721059
GO:0043015	gamma-tubulin binding	1/599	35/18639	0.0285714285714286	0.889053183877892	0.681560845145524	0.887394320721059
GO:0004222	metalloendopeptidase activity	3/599	110/18639	0.0272727272727273	0.848641675519806	0.690974664225617	0.891784523614534
GO:0004190	aspartic-type endopeptidase activity	1/599	36/18639	0.0277777777777778	0.864357262103506	0.691813750636699	0.891784523614534
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/599	36/18639	0.0277777777777778	0.864357262103506	0.691813750636699	0.891784523614534
GO:0005484	SNAP receptor activity	1/599	36/18639	0.0277777777777778	0.864357262103506	0.691813750636699	0.891784523614534
GO:0016409	palmitoyltransferase activity	1/599	36/18639	0.0277777777777778	0.864357262103506	0.691813750636699	0.891784523614534
GO:0003684	damaged DNA binding	2/599	74/18639	0.027027027027027	0.840996255019627	0.692320292888916	0.891784523614534
GO:0048029	monosaccharide binding	2/599	74/18639	0.027027027027027	0.840996255019627	0.692320292888916	0.891784523614534
GO:0015631	tubulin binding	11/599	385/18639	0.0285714285714286	0.889053183877892	0.696832041835327	0.895721792400159
GO:0044183	protein folding chaperone	2/599	75/18639	0.0266666666666667	0.829782971619366	0.699372488973379	0.895721792400159
GO:0019213	deacetylase activity	1/599	37/18639	0.027027027027027	0.840996255019627	0.70173707286261	0.895721792400159
GO:0022829	wide pore channel activity	1/599	37/18639	0.027027027027027	0.840996255019627	0.70173707286261	0.895721792400159
GO:0030280	structural constituent of skin epidermis	1/599	37/18639	0.027027027027027	0.840996255019627	0.70173707286261	0.895721792400159
GO:0070001	aspartic-type peptidase activity	1/599	37/18639	0.027027027027027	0.840996255019627	0.70173707286261	0.895721792400159
GO:0042887	amide transmembrane transporter activity	1/599	38/18639	0.0263157894736842	0.818864774624374	0.711341389245542	0.906611574528632
GO:0003724	RNA helicase activity	2/599	77/18639	0.025974025974026	0.80823016716172	0.71307456050229	0.907451812687402
GO:0001221	transcription coregulator binding	3/599	115/18639	0.0260869565217391	0.811744211366771	0.719419061691137	0.911407956715158
GO:0035401	histone H3Y41 kinase activity	3/599	115/18639	0.0260869565217391	0.811744211366771	0.719419061691137	0.911407956715158
GO:0140801	histone H2AXY142 kinase activity	3/599	115/18639	0.0260869565217391	0.811744211366771	0.719419061691137	0.911407956715158
GO:0000217	DNA secondary structure binding	1/599	39/18639	0.0256410256410256	0.797868241941698	0.720636938293546	0.911584150985099
GO:0008186	ATP-dependent activity, acting on RNA	2/599	79/18639	0.0253164556962025	0.787768643942436	0.726249453856057	0.914748394248563
GO:0016835	carbon-oxygen lyase activity	2/599	79/18639	0.0253164556962025	0.787768643942436	0.726249453856057	0.914748394248563
GO:0003774	cytoskeletal motor activity	4/599	153/18639	0.0261437908496732	0.813512717273888	0.728797916823517	0.914748394248563
GO:0004177	aminopeptidase activity	1/599	40/18639	0.025	0.777921535893155	0.729633630442049	0.914748394248563
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/599	40/18639	0.025	0.777921535893155	0.729633630442049	0.914748394248563
GO:0030331	nuclear estrogen receptor binding	1/599	40/18639	0.025	0.777921535893155	0.729633630442049	0.914748394248563
GO:0000049	tRNA binding	2/599	80/18639	0.025	0.777921535893155	0.732642855912444	0.917160315920022
GO:0001727	lipid kinase activity	1/599	41/18639	0.024390243902439	0.758947839895761	0.738341058549217	0.918202999761843
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/599	41/18639	0.024390243902439	0.758947839895761	0.738341058549217	0.918202999761843
GO:0140318	protein transporter activity	1/599	41/18639	0.024390243902439	0.758947839895761	0.738341058549217	0.918202999761843
GO:0140828	metal cation:monoatomic cation antiporter activity	1/599	41/18639	0.024390243902439	0.758947839895761	0.738341058549217	0.918202999761843
GO:0015101	organic cation transmembrane transporter activity	2/599	81/18639	0.0246913580246914	0.768317566314227	0.73890892288527	0.918202999761843
GO:0004520	DNA endonuclease activity	1/599	42/18639	0.0238095238095238	0.740877653231576	0.746768508056101	0.923893688590637
GO:0031492	nucleosomal DNA binding	1/599	42/18639	0.0238095238095238	0.740877653231576	0.746768508056101	0.923893688590637
GO:0051879	Hsp90 protein binding	1/599	42/18639	0.0238095238095238	0.740877653231576	0.746768508056101	0.923893688590637
GO:0003697	single-stranded DNA binding	3/599	121/18639	0.0247933884297521	0.771492432290732	0.750818386426386	0.925146087796087
GO:0015108	chloride transmembrane transporter activity	3/599	121/18639	0.0247933884297521	0.771492432290732	0.750818386426386	0.925146087796087
GO:0005254	chloride channel activity	2/599	83/18639	0.0240963855421687	0.749803890017499	0.751065344648658	0.925146087796087
GO:0004527	exonuclease activity	2/599	84/18639	0.0238095238095238	0.740877653231576	0.756958919876958	0.931048453123769
GO:0001223	transcription coactivator binding	1/599	44/18639	0.0227272727272727	0.707201396266505	0.762819134647254	0.934177056198449
GO:0016790	thiolester hydrolase activity	1/599	44/18639	0.0227272727272727	0.707201396266505	0.762819134647254	0.934177056198449
GO:0043014	alpha-tubulin binding	1/599	44/18639	0.0227272727272727	0.707201396266505	0.762819134647254	0.934177056198449
GO:0004715	non-membrane spanning protein tyrosine kinase activity	1/599	45/18639	0.0222222222222222	0.691485809682805	0.770459432487872	0.941597296484128
GO:0005261	monoatomic cation channel activity	9/599	341/18639	0.0263929618768328	0.821266137599812	0.771106898422505	0.941597296484128
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/599	46/18639	0.0217391304347826	0.676453509472309	0.777854011381051	0.946183401664894
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/599	46/18639	0.0217391304347826	0.676453509472309	0.777854011381051	0.946183401664894
GO:0016791	phosphatase activity	7/599	273/18639	0.0256410256410256	0.797868241941698	0.778221851073493	0.946183401664894
GO:0003727	single-stranded RNA binding	2/599	89/18639	0.0224719101123595	0.699255313162387	0.784646901359535	0.950335376954114
GO:0140359	ABC-type transporter activity	1/599	47/18639	0.0212765957446809	0.662060881611196	0.785010761081623	0.950335376954114
GO:0140938	histone H3 methyltransferase activity	1/599	47/18639	0.0212765957446809	0.662060881611196	0.785010761081623	0.950335376954114
GO:0016887	ATP hydrolysis activity	11/599	417/18639	0.026378896882494	0.820828479119876	0.788474812701858	0.953163400190372
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/599	48/18639	0.0208333333333333	0.648267946577629	0.791937318424142	0.954617737615407
GO:0032266	phosphatidylinositol-3-phosphate binding	1/599	48/18639	0.0208333333333333	0.648267946577629	0.791937318424142	0.954617737615407
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	9/599	349/18639	0.0257879656160458	0.802440552783771	0.793524758292279	0.955168690537003
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	2/599	91/18639	0.021978021978022	0.683887064521455	0.79492324760519	0.95549095907025
GO:0001222	transcription corepressor binding	1/599	49/18639	0.0204081632653061	0.635037988484208	0.798641075417523	0.95859617717018
GO:0015605	organophosphate ester transmembrane transporter activity	1/599	50/18639	0.02	0.622337228714524	0.805129187081046	0.963646123347711
GO:0032813	tumor necrosis factor receptor superfamily binding	1/599	50/18639	0.02	0.622337228714524	0.805129187081046	0.963646123347711
GO:0051087	protein-folding chaperone binding	3/599	134/18639	0.0223880597014925	0.696646151546109	0.809157448749299	0.966170439948096
GO:0016410	N-acyltransferase activity	2/599	94/18639	0.0212765957446809	0.662060881611196	0.809525055009766	0.966170439948096
GO:0030544	Hsp70 protein binding	1/599	51/18639	0.0196078431372549	0.610134537955416	0.811408579029965	0.967052537771962
GO:0015297	antiporter activity	3/599	135/18639	0.0222222222222222	0.691485809682805	0.813127608137303	0.967618841980551
GO:0016779	nucleotidyltransferase activity	3/599	136/18639	0.0220588235294118	0.686401355199843	0.817027670360489	0.967618841980551
GO:0030159	signaling receptor complex adaptor activity	1/599	52/18639	0.0192307692307692	0.598401181456273	0.817485954818703	0.967618841980551
GO:0016407	acetyltransferase activity	2/599	96/18639	0.0208333333333333	0.648267946577629	0.818738065814622	0.967618841980551
GO:0004864	protein phosphatase inhibitor activity	1/599	53/18639	0.0188679245283019	0.58711059312691	0.82336780304938	0.967618841980551
GO:0005246	calcium channel regulator activity	1/599	53/18639	0.0188679245283019	0.58711059312691	0.82336780304938	0.967618841980551
GO:0005544	calcium-dependent phospholipid binding	1/599	53/18639	0.0188679245283019	0.58711059312691	0.82336780304938	0.967618841980551
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/599	53/18639	0.0188679245283019	0.58711059312691	0.82336780304938	0.967618841980551
GO:0140296	general transcription initiation factor binding	1/599	53/18639	0.0188679245283019	0.58711059312691	0.82336780304938	0.967618841980551
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/599	53/18639	0.0188679245283019	0.58711059312691	0.82336780304938	0.967618841980551
GO:0008170	N-methyltransferase activity	2/599	98/18639	0.0204081632653061	0.635037988484208	0.827550039740118	0.967618841980551
GO:0042578	phosphoric ester hydrolase activity	9/599	363/18639	0.0247933884297521	0.771492432290732	0.828793537408878	0.967618841980551
GO:0003925	G protein activity	1/599	54/18639	0.0185185185185185	0.576238174735671	0.829060404253158	0.967618841980551
GO:0015485	cholesterol binding	1/599	54/18639	0.0185185185185185	0.576238174735671	0.829060404253158	0.967618841980551
GO:0050661	NADP binding	1/599	54/18639	0.0185185185185185	0.576238174735671	0.829060404253158	0.967618841980551
GO:0019212	phosphatase inhibitor activity	1/599	56/18639	0.0178571428571429	0.555658239923682	0.839901987105376	0.977571872044136
GO:0170055	lipid transmembrane transporter activity	1/599	56/18639	0.0178571428571429	0.555658239923682	0.839901987105376	0.977571872044136
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/599	57/18639	0.0175438596491228	0.545909849749583	0.845062548356191	0.982225382889933
GO:0005253	monoatomic anion channel activity	2/599	103/18639	0.0194174757281553	0.604210901664587	0.847915497028245	0.984187630479213
GO:0003730	mRNA 3'-UTR binding	6/599	262/18639	0.0229007633587786	0.71259988020747	0.850453329081098	0.985779236040505
GO:0070063	RNA polymerase binding	1/599	59/18639	0.0169491525423729	0.527404431114004	0.854890780186608	0.988211923812629
GO:0005216	monoatomic ion channel activity	11/599	448/18639	0.0245535714285714	0.764030079895063	0.85651244677636	0.988211923812629
GO:0000149	SNARE binding	2/599	106/18639	0.0188679245283019	0.58711059312691	0.859060822385019	0.988211923812629
GO:0001098	basal transcription machinery binding	1/599	60/18639	0.0166666666666667	0.518614357262103	0.859568951481991	0.988211923812629
GO:0001099	basal RNA polymerase II transcription machinery binding	1/599	60/18639	0.0166666666666667	0.518614357262103	0.859568951481991	0.988211923812629
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/599	60/18639	0.0166666666666667	0.518614357262103	0.859568951481991	0.988211923812629
GO:0008509	monoatomic anion transmembrane transporter activity	3/599	149/18639	0.0201342281879195	0.626513988638783	0.861724318987143	0.989013268702038
GO:0019888	protein phosphatase regulator activity	2/599	107/18639	0.0186915887850467	0.581623578237873	0.862606839092783	0.989013268702038
GO:0016836	hydro-lyase activity	1/599	61/18639	0.0163934426229508	0.510112482552889	0.864096547050229	0.989378837747213
GO:0015179	L-amino acid transmembrane transporter activity	1/599	62/18639	0.0161290322580645	0.501884861866552	0.868478405609649	0.993050409661913
GO:0160215	deacylase activity	1/599	65/18639	0.0153846153846154	0.478720945165019	0.880795647507677	0.999936531529885
GO:0016829	lyase activity	4/599	200/18639	0.02	0.622337228714524	0.88832322751148	0.999936531529885
GO:0042054	histone methyltransferase activity	1/599	67/18639	0.0149253731343284	0.464430767697406	0.888360405723795	0.999936531529885
GO:0045182	translation regulator activity	8/599	356/18639	0.0224719101123595	0.699255313162387	0.889299331641551	0.999936531529885
GO:0030145	manganese ion binding	1/599	68/18639	0.0147058823529412	0.457600903466562	0.891961101231626	0.999936531529885
GO:0016279	protein-lysine N-methyltransferase activity	1/599	69/18639	0.0144927536231884	0.450969006314873	0.89544585166845	0.999936531529885
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/599	70/18639	0.0142857142857143	0.444526591938946	0.898818384509085	0.999936531529885
GO:0016278	lysine N-methyltransferase activity	1/599	70/18639	0.0142857142857143	0.444526591938946	0.898818384509085	0.999936531529885
GO:0015103	inorganic anion transmembrane transporter activity	3/599	165/18639	0.0181818181818182	0.565761117013204	0.903368697932264	0.999936531529885
GO:0008528	G protein-coupled peptide receptor activity	2/599	122/18639	0.0163934426229508	0.510112482552889	0.906829939598008	0.999936531529885
GO:0004518	nuclease activity	4/599	209/18639	0.0191387559808612	0.595538017908636	0.907138036442391	0.999936531529885
GO:0004521	RNA endonuclease activity	1/599	73/18639	0.0136986301369863	0.426258375831866	0.90829818049822	0.999936531529885
GO:0003924	GTPase activity	7/599	331/18639	0.0211480362537764	0.658060513746476	0.910783428486966	0.999936531529885
GO:0004519	endonuclease activity	2/599	127/18639	0.015748031496063	0.490029313948444	0.918337066635707	0.999936531529885
GO:0001653	peptide receptor activity	2/599	128/18639	0.015625	0.486200959933222	0.920472251952185	0.999936531529885
GO:0031490	chromatin DNA binding	2/599	128/18639	0.015625	0.486200959933222	0.920472251952185	0.999936531529885
GO:0016798	hydrolase activity, acting on glycosyl bonds	2/599	130/18639	0.0153846153846154	0.478720945165019	0.924586014936357	0.999936531529885
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	2/599	130/18639	0.0153846153846154	0.478720945165019	0.924586014936357	0.999936531529885
GO:0033192	calmodulin-dependent protein phosphatase activity	1/599	81/18639	0.0123456790123457	0.384158783157114	0.929463503587892	0.999936531529885
GO:0140791	histone H2AXS140 phosphatase activity	1/599	81/18639	0.0123456790123457	0.384158783157114	0.929463503587892	0.999936531529885
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	1/599	81/18639	0.0123456790123457	0.384158783157114	0.929463503587892	0.999936531529885
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	1/599	81/18639	0.0123456790123457	0.384158783157114	0.929463503587892	0.999936531529885
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	1/599	81/18639	0.0123456790123457	0.384158783157114	0.929463503587892	0.999936531529885
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	1/599	81/18639	0.0123456790123457	0.384158783157114	0.929463503587892	0.999936531529885
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	1/599	81/18639	0.0123456790123457	0.384158783157114	0.929463503587892	0.999936531529885
GO:1990439	MAP kinase serine/threonine phosphatase activity	1/599	81/18639	0.0123456790123457	0.384158783157114	0.929463503587892	0.999936531529885
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	1/599	82/18639	0.0121951219512195	0.379473919947881	0.931740223134764	0.999936531529885
GO:0033549	MAP kinase phosphatase activity	1/599	82/18639	0.0121951219512195	0.379473919947881	0.931740223134764	0.999936531529885
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	1/599	83/18639	0.0120481927710843	0.37490194500875	0.933943575311424	0.999936531529885
GO:0099094	ligand-gated monoatomic cation channel activity	2/599	136/18639	0.0147058823529412	0.457600903466562	0.935755942759291	0.999936531529885
GO:0017018	myosin phosphatase activity	1/599	84/18639	0.0119047619047619	0.370438826615788	0.936075920557622	0.999936531529885
GO:0050660	flavin adenine dinucleotide binding	1/599	86/18639	0.0116279069767442	0.361823970182863	0.940136655353897	0.999936531529885
GO:0141003	histone H2AX kinase activity	7/599	354/18639	0.019774011299435	0.615305169633004	0.940298291985137	0.999936531529885
GO:0140767	enzyme-substrate adaptor activity	2/599	139/18639	0.0143884892086331	0.447724624974478	0.94073505051271	0.999936531529885
GO:0140996	histone H3 kinase activity	7/599	357/18639	0.0196078431372549	0.610134537955416	0.943431044013144	0.999936531529885
GO:0035173	histone kinase activity	7/599	360/18639	0.0194444444444444	0.605050083472454	0.946417269707455	0.999936531529885
GO:0052689	carboxylic ester hydrolase activity	1/599	92/18639	0.0108695652173913	0.338226754736154	0.950837753674774	0.999936531529885
GO:0015085	calcium ion transmembrane transporter activity	2/599	147/18639	0.0136054421768707	0.423358658989472	0.9522820789157	0.999936531529885
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	4/599	243/18639	0.0164609053497942	0.512211710876152	0.955288521813495	0.999936531529885
GO:0008276	protein methyltransferase activity	1/599	95/18639	0.0105263157894737	0.32754590984975	0.955449093990197	0.999936531529885
GO:0015291	secondary active transmembrane transporter activity	5/599	287/18639	0.0174216027874564	0.542105599925544	0.955773225034144	0.999936531529885
GO:0019842	vitamin binding	2/599	150/18639	0.0133333333333333	0.414891485809683	0.956031450070875	0.999936531529885
GO:0004676	3-phosphoinositide-dependent protein kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0004711	ribosomal protein S6 kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0035175	histone H3S10 kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0035979	histone H2AXS139 kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0044022	histone H3S28 kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0044023	histone H4S1 kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0044024	histone H2AS1 kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0044025	histone H2BS14 kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0072354	histone H3T3 kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0072371	histone H2AS121 kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0072518	Rho-dependent protein serine/threonine kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0140823	histone H2BS36 kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0140855	histone H3S57 kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0140995	histone H2A kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0140997	histone H4 kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0140998	histone H2B kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:1990244	histone H2AT120 kinase activity	4/599	245/18639	0.0163265306122449	0.508030390787367	0.957234590998345	0.999936531529885
GO:0004677	DNA-dependent protein kinase activity	4/599	246/18639	0.016260162601626	0.505965226597174	0.958178047936128	0.999936531529885
GO:0140857	histone H3T45 kinase activity	4/599	246/18639	0.016260162601626	0.505965226597174	0.958178047936128	0.999936531529885
GO:0035402	histone H3T11 kinase activity	4/599	247/18639	0.0161943319838057	0.50391678438423	0.959102255561714	0.999936531529885
GO:0035403	histone H3T6 kinase activity	4/599	247/18639	0.0161943319838057	0.50391678438423	0.959102255561714	0.999936531529885
GO:0005249	voltage-gated potassium channel activity	1/599	98/18639	0.0102040816326531	0.317518994242104	0.959628551934985	0.999936531529885
GO:0004679	AMP-activated protein kinase activity	4/599	248/18639	0.0161290322580645	0.501884861866552	0.960007559723003	0.999936531529885
GO:0005506	iron ion binding	2/599	154/18639	0.012987012987013	0.40411508358086	0.960594333998445	0.999936531529885
GO:0015171	amino acid transmembrane transporter activity	1/599	102/18639	0.00980392156862745	0.305067268977708	0.964598600720946	0.999936531529885
GO:0004722	protein serine/threonine phosphatase activity	1/599	103/18639	0.00970873786407767	0.302105450832293	0.965742552717934	0.999936531529885
GO:0004497	monooxygenase activity	1/599	106/18639	0.00943396226415094	0.293555296563455	0.968957691356584	0.999936531529885
GO:0008013	beta-catenin binding	1/599	106/18639	0.00943396226415094	0.293555296563455	0.968957691356584	0.999936531529885
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/599	167/18639	0.0119760479041916	0.37265702318235	0.972492306643942	0.999936531529885
GO:0019001	guanyl nucleotide binding	7/599	400/18639	0.0175	0.544545075125209	0.974766753962934	0.999936531529885
GO:0032561	guanyl ribonucleotide binding	7/599	400/18639	0.0175	0.544545075125209	0.974766753962934	0.999936531529885
GO:0001216	DNA-binding transcription activator activity	9/599	491/18639	0.0183299389002037	0.570370168882965	0.978175746702553	0.999936531529885
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	3/599	229/18639	0.0131004366812227	0.407644472957112	0.979451227926195	0.999936531529885
GO:0046982	protein heterodimerization activity	6/599	369/18639	0.016260162601626	0.505965226597174	0.980181998233072	0.999936531529885
GO:0004540	RNA nuclease activity	1/599	121/18639	0.00826446280991736	0.257164144096911	0.981039779569391	0.999936531529885
GO:0051082	unfolded protein binding	1/599	121/18639	0.00826446280991736	0.257164144096911	0.981039779569391	0.999936531529885
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	2/599	181/18639	0.0110497237569061	0.343832723046698	0.981418371404107	0.999936531529885
GO:0005267	potassium channel activity	1/599	124/18639	0.00806451612903226	0.250942430933276	0.982820912208853	0.999936531529885
GO:0005525	GTP binding	6/599	378/18639	0.0158730158730159	0.493918435487718	0.983589357071405	0.999936531529885
GO:0015276	ligand-gated monoatomic ion channel activity	2/599	186/18639	0.010752688172043	0.334589907911035	0.983866699779511	0.999936531529885
GO:0022834	ligand-gated channel activity	2/599	188/18639	0.0106382978723404	0.331030440805598	0.984755688930147	0.999936531529885
GO:0046943	carboxylic acid transmembrane transporter activity	2/599	188/18639	0.0106382978723404	0.331030440805598	0.984755688930147	0.999936531529885
GO:0005342	organic acid transmembrane transporter activity	2/599	189/18639	0.0105820105820106	0.329278956991812	0.985182150332245	0.999936531529885
GO:0005262	calcium channel activity	1/599	131/18639	0.00763358778625954	0.23753329340249	0.986354011908756	0.999936531529885
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	8/599	484/18639	0.0165289256198347	0.514328288193822	0.988801668874875	0.999936531529885
GO:0008168	methyltransferase activity	2/599	204/18639	0.00980392156862745	0.305067268977708	0.990343711088479	0.999936531529885
GO:0022843	voltage-gated monoatomic cation channel activity	1/599	143/18639	0.00699300699300699	0.217600429620463	0.990806194446027	0.999936531529885
GO:0106310	protein serine kinase activity	5/599	361/18639	0.0138504155124654	0.430981460328618	0.991280305472859	0.999936531529885
GO:0008514	organic anion transmembrane transporter activity	3/599	269/18639	0.0111524163568773	0.347028194450478	0.992707446712432	0.999936531529885
GO:0016741	transferase activity, transferring one-carbon groups	2/599	215/18639	0.00930232558139535	0.28945917614629	0.992966551171695	0.999936531529885
GO:0015079	potassium ion transmembrane transporter activity	1/599	160/18639	0.00625	0.194480383973289	0.994747941754576	0.999936531529885
GO:0004674	protein serine/threonine kinase activity	6/599	433/18639	0.0138568129330254	0.43118052797773	0.995066478067006	0.999936531529885
GO:0140098	catalytic activity, acting on RNA	5/599	387/18639	0.0129198966408269	0.402026633536514	0.995251611747532	0.999936531529885
GO:0005244	voltage-gated monoatomic ion channel activity	1/599	173/18639	0.00578034682080925	0.179866251073562	0.996578427634808	0.999936531529885
GO:0022832	voltage-gated channel activity	1/599	175/18639	0.00571428571428571	0.177810636775578	0.996796811080618	0.999936531529885
GO:0016757	glycosyltransferase activity	2/599	267/18639	0.00749063670411985	0.233085104387462	0.998470693334234	0.999936531529885
GO:0016755	aminoacyltransferase activity	6/599	496/18639	0.0120967741935484	0.376413646399914	0.99885985951025	0.999936531529885
GO:0046873	metal ion transmembrane transporter activity	5/599	450/18639	0.0111111111111111	0.345742904841402	0.99897806517287	0.999936531529885
GO:0019787	ubiquitin-like protein transferase activity	5/599	479/18639	0.0104384133611691	0.324810662168332	0.999509009031437	0.999936531529885
GO:0022836	gated channel activity	2/599	318/18639	0.00628930817610063	0.195703531042303	0.999669378597899	0.999936531529885
GO:0004842	ubiquitin-protein transferase activity	4/599	449/18639	0.0089086859688196	0.277210346866158	0.99974330804528	0.999936531529885
GO:0030371	translation repressor activity	2/599	329/18639	0.0060790273556231	0.189160251888913	0.999763263951002	0.999936531529885
GO:0061630	ubiquitin protein ligase activity	2/599	353/18639	0.0056657223796034	0.176299498219412	0.999886227597621	0.999936531529885
GO:0061659	ubiquitin-like protein ligase activity	2/599	372/18639	0.00537634408602151	0.167294953955517	0.999936531529885	0.999936531529885