ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0019787	ubiquitin-like protein transferase activity	194/3863	479/18639	0.405010438413361	1.95417798643195	1.55803678771344e-23	2.0285638976029e-20
GO:0003712	transcription coregulator activity	198/3863	495/18639	0.4	1.93000258866166	3.17798573475239e-23	2.0688687133238e-20
GO:0016755	aminoacyltransferase activity	195/3863	496/18639	0.393145161290323	1.89692794752532	7.48903239453656e-22	3.25024005922887e-19
GO:0004842	ubiquitin-protein transferase activity	176/3863	449/18639	0.391982182628062	1.89131656795352	1.1238027913457e-19	3.65797808583025e-17
GO:0061659	ubiquitin-like protein ligase activity	145/3863	372/18639	0.389784946236559	1.88071488814476	3.46113048088228e-16	9.01278377221745e-14
GO:0044389	ubiquitin-like protein ligase binding	123/3863	322/18639	0.381987577639752	1.8430925342033	3.32436033698243e-13	7.21386193125187e-11
GO:0061630	ubiquitin protein ligase activity	131/3863	353/18639	0.371104815864023	1.79058313820593	6.75834902015832e-13	1.25705291774945e-10
GO:0031625	ubiquitin protein ligase binding	116/3863	302/18639	0.384105960264901	1.85331374407908	1.01600705811863e-12	1.65355148708807e-10
GO:0003714	transcription corepressor activity	84/3863	204/18639	0.411764705882353	1.98676737068112	2.14738128077964e-11	3.10654491952788e-09
GO:0140297	DNA-binding transcription factor binding	163/3863	488/18639	0.334016393442623	1.61163125999924	2.6515434670872e-11	3.45230959414754e-09
GO:0003713	transcription coactivator activity	97/3863	256/18639	0.37890625	1.82822510840021	1.74240827578817e-10	2.06237779552382e-08
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	120/3863	349/18639	0.343839541547278	1.65902801317621	1.59584298648342e-09	1.73148964033451e-07
GO:0140104	molecular carrier activity	92/3863	249/18639	0.369477911646586	1.78273331482804	2.29632713300468e-09	2.29985994397853e-07
GO:0140662	ATP-dependent protein folding chaperone	25/3863	40/18639	0.625	3.01562904478385	1.13407657396401e-08	1.05469121378653e-06
GO:0003725	double-stranded RNA binding	37/3863	75/18639	0.493333333333333	2.38033652601605	3.25032482759889e-08	2.82128195035584e-06
GO:0032182	ubiquitin-like protein binding	51/3863	120/18639	0.425	2.05062775045302	5.20386183334836e-08	4.23464256688722e-06
GO:0031072	heat shock protein binding	54/3863	131/18639	0.412213740458015	1.98893396541469	7.41179340723394e-08	5.67656177424623e-06
GO:0140030	modification-dependent protein binding	65/3863	173/18639	0.375722543352601	1.81286370322266	2.42361441347916e-07	1.7530810924166e-05
GO:0016887	ATP hydrolysis activity	130/3863	417/18639	0.311750599520384	1.50419866022791	2.60341036908049e-07	1.784021210812e-05
GO:0044183	protein folding chaperone	35/3863	75/18639	0.466666666666667	2.25166968677194	4.27422336581069e-07	2.78251941114276e-05
GO:0140597	protein carrier chaperone	68/3863	188/18639	0.361702127659574	1.74521510676852	6.69542583787696e-07	4.15116401948371e-05
GO:0043021	ribonucleoprotein complex binding	64/3863	177/18639	0.361581920903955	1.74463510839472	1.42560795784901e-06	8.26884576829783e-05
GO:0051082	unfolded protein binding	48/3863	121/18639	0.396694214876033	1.91405215404462	1.46070240146582e-06	8.26884576829783e-05
GO:0002039	p53 binding	32/3863	69/18639	0.463768115942029	2.23768416076714	1.56847877992251e-06	8.50899738107961e-05
GO:0016922	nuclear receptor binding	52/3863	137/18639	0.37956204379562	1.83138931770815	2.62052447008356e-06	0.000136476914401952
GO:0051087	protein-folding chaperone binding	51/3863	134/18639	0.380597014925373	1.83638306010718	2.96823282924673e-06	0.000148639967064586
GO:0017025	TBP-class protein binding	16/3863	25/18639	0.64	3.08800414185866	3.32438883358514e-06	0.000155970821396705
GO:0061650	ubiquitin-like protein conjugating enzyme activity	22/3863	41/18639	0.536585365853659	2.58902786283881	3.35421121283237e-06	0.000155970821396705
GO:0070063	RNA polymerase binding	28/3863	59/18639	0.474576271186441	2.28983357976807	3.97519000764011e-06	0.00017847232379129
GO:0060589	nucleoside-triphosphatase regulator activity	143/3863	490/18639	0.291836734693878	1.40811413356438	4.35649753178739e-06	0.000189071992879573
GO:0001221	transcription coregulator binding	45/3863	115/18639	0.391304347826087	1.88804601064728	4.72548772245368e-06	0.000198470484343054
GO:0001098	basal transcription machinery binding	28/3863	60/18639	0.466666666666667	2.25166968677194	5.9857815703426e-06	0.000236166291048063
GO:0001099	basal RNA polymerase II transcription machinery binding	28/3863	60/18639	0.466666666666667	2.25166968677194	5.9857815703426e-06	0.000236166291048063
GO:0030695	GTPase regulator activity	142/3863	489/18639	0.29038854805726	1.40112662367053	6.27002053966126e-06	0.000240104904195263
GO:0106310	protein serine kinase activity	110/3863	361/18639	0.304709141274238	1.47022357862038	6.80041588904341e-06	0.000252975471072415
GO:0031267	small GTPase binding	90/3863	283/18639	0.318021201413428	1.53445435494302	7.17145214750305e-06	0.000259367519334694
GO:0045296	cadherin binding	103/3863	334/18639	0.308383233532934	1.48795109754604	7.45012435779249e-06	0.000262163835509346
GO:0043130	ubiquitin binding	40/3863	100/18639	0.4	1.93000258866166	8.38551818214229e-06	0.000287314333503928
GO:0060590	ATPase regulator activity	24/3863	49/18639	0.489795918367347	2.36326847591224	9.7676421328518e-06	0.000326088975819822
GO:0140142	nucleocytoplasmic carrier activity	18/3863	32/18639	0.5625	2.71406614030546	1.09617436302557e-05	0.000356804755164824
GO:0140658	ATP-dependent chromatin remodeler activity	56/3863	158/18639	0.354430379746835	1.71012887602932	1.24776533262925e-05	0.000395602913694561
GO:0008094	ATP-dependent activity, acting on DNA	70/3863	210/18639	0.333333333333333	1.60833549055138	1.27613843127278e-05	0.000395602913694561
GO:0140296	general transcription initiation factor binding	25/3863	53/18639	0.471698113207547	2.27594644889347	1.47977406809557e-05	0.00044806182247917
GO:0000287	magnesium ion binding	75/3863	230/18639	0.326086956521739	1.5733716755394	1.53226247012686e-05	0.000453410394569358
GO:0140674	ATP-dependent histone chaperone activity	54/3863	152/18639	0.355263157894737	1.7141470359824	1.63757462911876e-05	0.000473804926025027
GO:0031624	ubiquitin conjugating enzyme binding	17/3863	30/18639	0.566666666666667	2.73417033393735	1.69026369967465e-05	0.000478418116733998
GO:0140416	transcription regulator inhibitor activity	18/3863	33/18639	0.545454545454545	2.63182171181136	1.94467302889642e-05	0.000516452844754851
GO:0004721	phosphoprotein phosphatase activity	60/3863	175/18639	0.342857142857143	1.65428793313857	1.99796171696627e-05	0.000516452844754851
GO:0061775	cohesin loader activity	54/3863	153/18639	0.352941176470588	1.70294346058382	2.02603414843098e-05	0.000516452844754851
GO:0140713	histone chaperone activity	57/3863	164/18639	0.347560975609756	1.67698395661151	2.03036852738883e-05	0.000516452844754851
GO:0008139	nuclear localization sequence binding	15/3863	25/18639	0.6	2.89500388299249	2.09891666576959e-05	0.000516452844754851
GO:0000993	RNA polymerase II complex binding	19/3863	36/18639	0.527777777777778	2.54653119337303	2.13781483509777e-05	0.000516452844754851
GO:0044390	ubiquitin-like protein conjugating enzyme binding	19/3863	36/18639	0.527777777777778	2.54653119337303	2.13781483509777e-05	0.000516452844754851
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	47/3863	128/18639	0.3671875	1.77168206381051	2.14197032386804e-05	0.000516452844754851
GO:0005525	GTP binding	112/3863	378/18639	0.296296296296296	1.42963154715679	2.23990023640851e-05	0.000530245474146161
GO:0004402	histone acetyltransferase activity	21/3863	42/18639	0.5	2.41250323582708	2.34337578280812e-05	0.000535276363020382
GO:0043175	RNA polymerase core enzyme binding	21/3863	42/18639	0.5	2.41250323582708	2.34337578280812e-05	0.000535276363020382
GO:0051020	GTPase binding	96/3863	315/18639	0.304761904761905	1.47047816278984	2.52320381173495e-05	0.000561704882699806
GO:0140537	transcription regulator activator activity	9/3863	11/18639	0.818181818181818	3.94773256771704	2.55239571836695e-05	0.000561704882699806
GO:0016779	nucleotidyltransferase activity	49/3863	136/18639	0.360294117647059	1.73842144934598	2.58850176359358e-05	0.000561704882699806
GO:0000510	H3-H4 histone complex chaperone activity	53/3863	151/18639	0.350993377483444	1.69354531786537	2.86523670644126e-05	0.000582896592466643
GO:0140584	chromatin extrusion motor activity	53/3863	151/18639	0.350993377483444	1.69354531786537	2.86523670644126e-05	0.000582896592466643
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	53/3863	151/18639	0.350993377483444	1.69354531786537	2.86523670644126e-05	0.000582896592466643
GO:0140849	ATP-dependent H2AZ histone chaperone activity	53/3863	151/18639	0.350993377483444	1.69354531786537	2.86523670644126e-05	0.000582896592466643
GO:0004674	protein serine/threonine kinase activity	125/3863	433/18639	0.288683602771363	1.39290025163226	2.95799973862e-05	0.000592510101489728
GO:0015616	DNA translocase activity	53/3863	152/18639	0.348684210526316	1.68240357235309	3.52246993975531e-05	0.000692080886375582
GO:0001222	transcription corepressor binding	23/3863	49/18639	0.469387755102041	2.26479895608256	3.56139933849186e-05	0.000692080886375582
GO:0005521	lamin binding	11/3863	16/18639	0.6875	3.31719194926223	4.59390883969026e-05	0.000866850624532857
GO:0070411	I-SMAD binding	11/3863	16/18639	0.6875	3.31719194926223	4.59390883969026e-05	0.000866850624532857
GO:0061733	protein-lysine-acetyltransferase activity	22/3863	47/18639	0.468085106382979	2.2585136675828	5.52889478934157e-05	0.00100108436965364
GO:0010485	histone H4 acetyltransferase activity	18/3863	35/18639	0.514285714285714	2.48143189970785	5.53595043126439e-05	0.00100108436965364
GO:0061631	ubiquitin conjugating enzyme activity	18/3863	35/18639	0.514285714285714	2.48143189970785	5.53595043126439e-05	0.00100108436965364
GO:0042393	histone binding	77/3863	247/18639	0.311740890688259	1.50415181505008	6.71768138907125e-05	0.00119813988610558
GO:0043022	ribosome binding	41/3863	112/18639	0.366071428571429	1.76629701194482	7.55938418331928e-05	0.00133004300090293
GO:0005048	signal sequence binding	23/3863	51/18639	0.450980392156863	2.17598331074599	7.78344089131323e-05	0.00135120533873198
GO:0019783	ubiquitin-like protein peptidase activity	45/3863	127/18639	0.354330708661417	1.70964796239714	8.5839817448071e-05	0.0014514732768492
GO:0042826	histone deacetylase binding	45/3863	127/18639	0.354330708661417	1.70964796239714	8.5839817448071e-05	0.0014514732768492
GO:0140517	protein-RNA adaptor activity	13/3863	22/18639	0.590909090909091	2.85114018779564	9.46105739975818e-05	0.00157926881211348
GO:1905394	retromer complex binding	8/3863	10/18639	0.8	3.86000517732332	0.000101499847219129	0.00167282026682666
GO:0051787	misfolded protein binding	11/3863	17/18639	0.647058823529412	3.12206301107034	0.000105696628784851	0.00172021263347345
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	32/3863	82/18639	0.390243902439024	1.88292935479187	0.000113183796704092	0.00181932473220651
GO:0140789	histone phosphatase activity	47/3863	136/18639	0.345588235294118	1.66746547182166	0.000121249948637319	0.001925212599095
GO:0019789	SUMO transferase activity	15/3863	28/18639	0.535714285714286	2.58482489552901	0.000127049651960768	0.0019692696053919
GO:0051537	2 iron, 2 sulfur cluster binding	15/3863	28/18639	0.535714285714286	2.58482489552901	0.000127049651960768	0.0019692696053919
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	32/3863	83/18639	0.385542168674699	1.860243458951	0.000147957517857938	0.00226636103824748
GO:0003689	DNA clamp loader activity	53/3863	160/18639	0.33125	1.59828339373544	0.000163145618338154	0.00246994877995671
GO:0008234	cysteine-type peptidase activity	60/3863	187/18639	0.320855614973262	1.54813041871256	0.000171163842774532	0.002561555440143
GO:0019001	guanyl nucleotide binding	113/3863	400/18639	0.2825	1.3630643282423	0.000181228662024528	0.00265123278602174
GO:0032561	guanyl ribonucleotide binding	113/3863	400/18639	0.2825	1.3630643282423	0.000181228662024528	0.00265123278602174
GO:0004725	protein tyrosine phosphatase activity	36/3863	98/18639	0.36734693877551	1.77245135693418	0.000186038845437209	0.00269136196399162
GO:0010484	histone H3 acetyltransferase activity	15/3863	29/18639	0.517241379310345	2.49569300257974	0.000212892752351368	0.00286595576365444
GO:0033192	calmodulin-dependent protein phosphatase activity	31/3863	81/18639	0.382716049382716	1.84660741507752	0.00021791829539308	0.00286595576365444
GO:0140791	histone H2AXS140 phosphatase activity	31/3863	81/18639	0.382716049382716	1.84660741507752	0.00021791829539308	0.00286595576365444
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	31/3863	81/18639	0.382716049382716	1.84660741507752	0.00021791829539308	0.00286595576365444
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	31/3863	81/18639	0.382716049382716	1.84660741507752	0.00021791829539308	0.00286595576365444
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	31/3863	81/18639	0.382716049382716	1.84660741507752	0.00021791829539308	0.00286595576365444
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	31/3863	81/18639	0.382716049382716	1.84660741507752	0.00021791829539308	0.00286595576365444
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	31/3863	81/18639	0.382716049382716	1.84660741507752	0.00021791829539308	0.00286595576365444
GO:1990439	MAP kinase serine/threonine phosphatase activity	31/3863	81/18639	0.382716049382716	1.84660741507752	0.00021791829539308	0.00286595576365444
GO:0140852	histone ubiquitin ligase activity	9/3863	13/18639	0.692307692307692	3.34038909576057	0.000220342640047088	0.00286886117341308
GO:0004722	protein serine/threonine phosphatase activity	37/3863	103/18639	0.359223300970874	1.73325475195343	0.000256794145089594	0.00329157179108556
GO:0004386	helicase activity	51/3863	155/18639	0.329032258064516	1.58758277454427	0.000257865071191035	0.00329157179108556
GO:0033549	MAP kinase phosphatase activity	31/3863	82/18639	0.378048780487805	1.82408781245462	0.000281580441655014	0.00355939548577504
GO:0046332	SMAD binding	30/3863	79/18639	0.379746835443038	1.83228093860284	0.000320269355418822	0.00400952596880102
GO:0043995	histone H4K5 acetyltransferase activity	15/3863	30/18639	0.5	2.41250323582708	0.000344539750707148	0.00419243696654867
GO:0043996	histone H4K8 acetyltransferase activity	15/3863	30/18639	0.5	2.41250323582708	0.000344539750707148	0.00419243696654867
GO:0043997	histone H4K12 acetyltransferase activity	15/3863	30/18639	0.5	2.41250323582708	0.000344539750707148	0.00419243696654867
GO:0140097	catalytic activity, acting on DNA	96/3863	336/18639	0.285714285714286	1.37857327761547	0.000348962968081732	0.00420694244854088
GO:0035091	phosphatidylinositol binding	83/3863	284/18639	0.292253521126761	1.41012513080033	0.000393168394414231	0.00469637843603054
GO:0017018	myosin phosphatase activity	31/3863	84/18639	0.369047619047619	1.78065715025332	0.000460228361569075	0.00544743024329941
GO:0003724	RNA helicase activity	29/3863	77/18639	0.376623376623377	1.81721022958403	0.000469603997006989	0.00546509309857648
GO:0034212	protein N-acetyltransferase activity	22/3863	53/18639	0.415094339622642	2.00283287502625	0.000471601061518861	0.00546509309857648
GO:0015036	disulfide oxidoreductase activity	18/3863	40/18639	0.45	2.17125291224437	0.000474312995498573	0.00546509309857648
GO:0061665	SUMO ligase activity	9/3863	14/18639	0.642857142857143	3.10178987463481	0.00050318566043947	0.005746909911335
GO:0004197	cysteine-type endopeptidase activity	32/3863	88/18639	0.363636363636364	1.75454780787424	0.00050826878136157	0.00575448655071969
GO:0017056	structural constituent of nuclear pore	13/3863	25/18639	0.52	2.50900336526016	0.000526867096250074	0.0058521427291957
GO:0140857	histone H3T45 kinase activity	73/3863	246/18639	0.296747967479675	1.43181086353965	0.00052831880156982	0.0058521427291957
GO:0005085	guanyl-nucleotide exchange factor activity	69/3863	230/18639	0.3	1.44750194149625	0.000530378526916354	0.0058521427291957
GO:0036408	histone H3K14 acetyltransferase activity	14/3863	28/18639	0.5	2.41250323582708	0.000542125240781105	0.00588205886247499
GO:0097718	disordered domain specific binding	14/3863	28/18639	0.5	2.41250323582708	0.000542125240781105	0.00588205886247499
GO:0003727	single-stranded RNA binding	32/3863	89/18639	0.359550561797753	1.73483378756104	0.000637916112849398	0.00684754438538999
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	22/3863	54/18639	0.407407407407407	1.96574337734058	0.00064162858296281	0.00684754438538999
GO:0140223	general transcription initiation factor activity	26/3863	68/18639	0.382352941176471	1.84485541563247	0.000692542027091557	0.00705829663250191
GO:0000995	RNA polymerase III general transcription initiation factor activity	8/3863	12/18639	0.666666666666667	3.21667098110277	0.000745957136488128	0.00705829663250191
GO:0008186	ATP-dependent activity, acting on RNA	29/3863	79/18639	0.367088607594937	1.77120490731608	0.000764272137203471	0.00705829663250191
GO:0061608	nuclear import signal receptor activity	11/3863	20/18639	0.55	2.65375355940979	0.00077015483099525	0.00705829663250191
GO:0004676	3-phosphoinositide-dependent protein kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0004711	ribosomal protein S6 kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0035175	histone H3S10 kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0035979	histone H2AXS139 kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0044022	histone H3S28 kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0044023	histone H4S1 kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0044024	histone H2AS1 kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0044025	histone H2BS14 kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0072354	histone H3T3 kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0072371	histone H2AS121 kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0072518	Rho-dependent protein serine/threonine kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0140823	histone H2BS36 kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0140855	histone H3S57 kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0140995	histone H2A kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0140997	histone H4 kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0140998	histone H2B kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:1990244	histone H2AT120 kinase activity	72/3863	245/18639	0.293877551020408	1.41796108554734	0.00077521998344683	0.00705829663250191
GO:0044013	histone H2B acetyltransferase activity	12/3863	23/18639	0.521739130434783	2.51739468086304	0.000831505886722915	0.00751819905911969
GO:0097602	cullin family protein binding	13/3863	26/18639	0.5	2.41250323582708	0.000854815517692424	0.00767565382093473
GO:0004677	DNA-dependent protein kinase activity	72/3863	246/18639	0.292682926829268	1.4121970160939	0.000877385989740772	0.00782435999070195
GO:0140098	catalytic activity, acting on RNA	106/3863	387/18639	0.27390180878553	1.32157799998796	0.000933948760370949	0.00827211759185697
GO:0051879	Hsp90 protein binding	18/3863	42/18639	0.428571428571429	2.06785991642321	0.000965989750950659	0.00849809902525512
GO:0035402	histone H3T11 kinase activity	72/3863	247/18639	0.291497975708502	1.40647961926761	0.000991401319759316	0.00860536345551086
GO:0035403	histone H3T6 kinase activity	72/3863	247/18639	0.291497975708502	1.40647961926761	0.000991401319759316	0.00860536345551086
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	71/3863	243/18639	0.292181069958848	1.40977555344628	0.000998173241028086	0.00860676529681171
GO:0000774	adenyl-nucleotide exchange factor activity	9/3863	15/18639	0.6	2.89500388299249	0.00102658825157167	0.00873606472906085
GO:0061578	K63-linked deubiquitinase activity	9/3863	15/18639	0.6	2.89500388299249	0.00102658825157167	0.00873606472906085
GO:0099122	RNA polymerase II C-terminal domain binding	7/3863	10/18639	0.7	3.37750453015791	0.00108030680120984	0.00913350295568321
GO:0004679	AMP-activated protein kinase activity	72/3863	248/18639	0.290322580645161	1.40080833048024	0.00111842982180668	0.00939481050317612
GO:0016791	phosphatase activity	78/3863	273/18639	0.285714285714286	1.37857327761547	0.00118383701162314	0.00988048582777777
GO:0001671	ATPase activator activity	13/3863	27/18639	0.481481481481481	2.32315126412978	0.00133788444106238	0.0110641151105627
GO:0043998	histone H2A acetyltransferase activity	12/3863	24/18639	0.5	2.41250323582708	0.0013511476978337	0.0110641151105627
GO:0140033	acetylation-dependent protein binding	12/3863	24/18639	0.5	2.41250323582708	0.0013511476978337	0.0110641151105627
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	31/3863	89/18639	0.348314606741573	1.68062023169976	0.00140206573051133	0.0113384446032655
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	31/3863	89/18639	0.348314606741573	1.68062023169976	0.00140206573051133	0.0113384446032655
GO:0005096	GTPase activator activity	77/3863	271/18639	0.284132841328413	1.37094279821908	0.00149941258014737	0.0120508344404437
GO:0004535	poly(A)-specific ribonuclease activity	8/3863	13/18639	0.615384615384615	2.96923475178717	0.00158694033079379	0.0126760509858498
GO:1990841	promoter-specific chromatin binding	25/3863	68/18639	0.367647058823529	1.77389943810815	0.00167151117488352	0.0132701679859655
GO:0140463	chromatin-protein adaptor activity	21/3863	54/18639	0.388888888888889	1.87639140564328	0.00170934766798131	0.013488307052798
GO:0140793	histone H2AXY142 phosphatase activity	31/3863	90/18639	0.344444444444444	1.66194667356976	0.00172062699530661	0.0134955201680072
GO:0140327	flippase activity	9/3863	16/18639	0.5625	2.71406614030546	0.00191606913695257	0.0149384551874985
GO:0046966	nuclear thyroid hormone receptor binding	13/3863	28/18639	0.464285714285714	2.24018157612514	0.00202754241463948	0.0150734032619438
GO:0046527	glucosyltransferase activity	10/3863	19/18639	0.526315789473684	2.53947709034429	0.00208833490051584	0.0150734032619438
GO:1990380	K48-linked deubiquitinase activity	10/3863	19/18639	0.526315789473684	2.53947709034429	0.00208833490051584	0.0150734032619438
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	12/3863	25/18639	0.48	2.31600310639399	0.0021120220992955	0.0150734032619438
GO:0008080	N-acetyltransferase activity	25/3863	69/18639	0.36231884057971	1.74819075059933	0.00211278913436148	0.0150734032619438
GO:0032931	histone H3K56 acetyltransferase activity	11/3863	22/18639	0.5	2.41250323582708	0.00214176620849432	0.0150734032619438
GO:0043992	histone H3K9 acetyltransferase activity	11/3863	22/18639	0.5	2.41250323582708	0.00214176620849432	0.0150734032619438
GO:0043993	histone H3K18 acetyltransferase activity	11/3863	22/18639	0.5	2.41250323582708	0.00214176620849432	0.0150734032619438
GO:0043994	histone H3K23 acetyltransferase activity	11/3863	22/18639	0.5	2.41250323582708	0.00214176620849432	0.0150734032619438
GO:0043999	histone H2AK5 acetyltransferase activity	11/3863	22/18639	0.5	2.41250323582708	0.00214176620849432	0.0150734032619438
GO:0044012	histone H2AK9 acetyltransferase activity	11/3863	22/18639	0.5	2.41250323582708	0.00214176620849432	0.0150734032619438
GO:0044014	histone H2BK5 acetyltransferase activity	11/3863	22/18639	0.5	2.41250323582708	0.00214176620849432	0.0150734032619438
GO:0044015	histone H2BK12 acetyltransferase activity	11/3863	22/18639	0.5	2.41250323582708	0.00214176620849432	0.0150734032619438
GO:0044016	histone H3K4 acetyltransferase activity	11/3863	22/18639	0.5	2.41250323582708	0.00214176620849432	0.0150734032619438
GO:0044017	histone H3K27 acetyltransferase activity	11/3863	22/18639	0.5	2.41250323582708	0.00214176620849432	0.0150734032619438
GO:0044018	histone H3K36 acetyltransferase activity	11/3863	22/18639	0.5	2.41250323582708	0.00214176620849432	0.0150734032619438
GO:0046972	histone H4K16 acetyltransferase activity	11/3863	22/18639	0.5	2.41250323582708	0.00214176620849432	0.0150734032619438
GO:0140908	histone H3K122 acetyltransferase activity	11/3863	22/18639	0.5	2.41250323582708	0.00214176620849432	0.0150734032619438
GO:0046915	transition metal ion transmembrane transporter activity	18/3863	45/18639	0.4	1.93000258866166	0.00247698295134911	0.0173388806594438
GO:0005154	epidermal growth factor receptor binding	15/3863	35/18639	0.428571428571429	2.06785991642321	0.00251491955622342	0.0175102955198016
GO:0101005	deubiquitinase activity	37/3863	115/18639	0.321739130434783	1.55239338653221	0.00263021317967067	0.018215625318783
GO:0051059	NF-kappaB binding	14/3863	32/18639	0.4375	2.11094033134869	0.00275413734438024	0.018972946150175
GO:0016763	pentosyltransferase activity	19/3863	49/18639	0.387755102040816	1.87092087676386	0.0028964580842316	0.0198483601351028
GO:0008474	palmitoyl-(protein) hydrolase activity	8/3863	14/18639	0.571428571428571	2.75714655523095	0.00303194655793288	0.0205603875959823
GO:0098599	palmitoyl hydrolase activity	8/3863	14/18639	0.571428571428571	2.75714655523095	0.00303194655793288	0.0205603875959823
GO:0004659	prenyltransferase activity	9/3863	17/18639	0.529411764705882	2.55441519087573	0.00332687762067598	0.0224349242138854
GO:0070577	lysine-acetylated histone binding	11/3863	23/18639	0.478260869565217	2.30761179079112	0.0033428381701181	0.0224349242138854
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	65/3863	229/18639	0.283842794759825	1.36954332164856	0.00341397468338263	0.0227948463475086
GO:0019003	GDP binding	26/3863	75/18639	0.346666666666667	1.67266891017344	0.00352601588381169	0.0234228197996062
GO:0016504	peptidase activator activity	21/3863	57/18639	0.368421052631579	1.777633963241	0.00368930959743461	0.0243831527708623
GO:0035173	histone kinase activity	96/3863	360/18639	0.266666666666667	1.28666839244111	0.00376546523903778	0.0247607865718545
GO:0003924	GTPase activity	89/3863	331/18639	0.268882175226586	1.29735823558072	0.00401586490268478	0.026274653785405
GO:0051536	iron-sulfur cluster binding	26/3863	76/18639	0.342105263157895	1.65066010872379	0.00432124332644148	0.0281312940551341
GO:0141003	histone H2AX kinase activity	94/3863	354/18639	0.265536723163842	1.28121640772737	0.00467826612229571	0.0303039924936767
GO:0005049	nuclear export signal receptor activity	7/3863	12/18639	0.583333333333333	2.81458710846492	0.00480845557018408	0.0308404391742841
GO:1990247	N6-methyladenosine-containing RNA reader activity	7/3863	12/18639	0.583333333333333	2.81458710846492	0.00480845557018408	0.0308404391742841
GO:0030544	Hsp70 protein binding	19/3863	51/18639	0.372549019607843	1.79755143061625	0.00486983885783662	0.031081030357369
GO:0017124	SH3 domain binding	36/3863	115/18639	0.31304347826087	1.51043680851782	0.00492601832989678	0.0312862237342712
GO:0016407	acetyltransferase activity	31/3863	96/18639	0.322916666666667	1.55807500647165	0.00525243248609662	0.0330930509802039
GO:0051540	metal cluster binding	26/3863	77/18639	0.337662337662338	1.62922296445465	0.00526133759823519	0.0330930509802039
GO:0042809	nuclear vitamin D receptor binding	8/3863	15/18639	0.533333333333333	2.57333678488222	0.00532378462234571	0.033324844126414
GO:0015035	protein-disulfide reductase activity	14/3863	34/18639	0.411764705882353	1.98676737068112	0.00535895724113293	0.0333845087461965
GO:0004843	cysteine-type deubiquitinase activity	34/3863	108/18639	0.314814814814815	1.51898351885409	0.00559362314471422	0.0346804634972282
GO:0031593	polyubiquitin modification-dependent protein binding	21/3863	59/18639	0.355932203389831	1.71737518482606	0.00586321615915089	0.0361796561100211
GO:0019903	protein phosphatase binding	43/3863	144/18639	0.298611111111111	1.44080054361895	0.00591538373407088	0.0363293850083032
GO:0140996	histone H3 kinase activity	94/3863	357/18639	0.263305322128852	1.27044988329269	0.00601791061255104	0.0367855381105232
GO:0035064	methylated histone binding	25/3863	74/18639	0.337837837837838	1.63006975393721	0.00609030322877947	0.0370540878685555
GO:0140303	intramembrane lipid transporter activity	17/3863	45/18639	0.377777777777778	1.8227802226249	0.00641751669764062	0.0388632871643167
GO:0051019	mitogen-activated protein kinase binding	12/3863	28/18639	0.428571428571429	2.06785991642321	0.00665363235464216	0.0401066172488152
GO:0035591	signaling adaptor activity	39/3863	129/18639	0.302325581395349	1.45872288677916	0.00677587727019852	0.0406552636211911
GO:0019902	phosphatase binding	54/3863	190/18639	0.284210526315789	1.37131762878592	0.00692038499832508	0.04133184067807
GO:0016303	1-phosphatidylinositol-3-kinase activity	6/3863	10/18639	0.6	2.89500388299249	0.0076410668426367	0.0452212228596045
GO:0098505	G-rich strand telomeric DNA binding	6/3863	10/18639	0.6	2.89500388299249	0.0076410668426367	0.0452212228596045
GO:0016251	RNA polymerase II general transcription initiation factor activity	19/3863	53/18639	0.358490566037736	1.72971930115904	0.00783284012354162	0.0461464155694624
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	10/3863	22/18639	0.454545454545455	2.1931847598428	0.0079451289672667	0.0465971077269425
GO:0005548	phospholipid transporter activity	23/3863	68/18639	0.338235294117647	1.63198748305949	0.00817393322913757	0.0477037390431036
GO:0070717	poly-purine tract binding	13/3863	32/18639	0.40625	1.9601588791095	0.0082070948891361	0.0477037390431036
GO:0003756	protein disulfide isomerase activity	9/3863	19/18639	0.473684210526316	2.28552938130986	0.00845691634692822	0.0487208189544272
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	9/3863	19/18639	0.473684210526316	2.28552938130986	0.00845691634692822	0.0487208189544272
GO:0140333	glycerophospholipid flippase activity	7/3863	13/18639	0.538461538461538	2.59808040781378	0.00856689001613944	0.0491369638811169
GO:0004707	MAP kinase activity	8/3863	16/18639	0.5	2.41250323582708	0.00873150010773886	0.0496437255033887
GO:0140328	floppase activity	8/3863	16/18639	0.5	2.41250323582708	0.00873150010773886	0.0496437255033887
GO:0140767	enzyme-substrate adaptor activity	41/3863	139/18639	0.294964028776978	1.4232033477541	0.00884971805741139	0.0499840332313167
GO:0140034	methylation-dependent protein binding	25/3863	76/18639	0.328947368421053	1.58717318146518	0.00886813492813682	0.0499840332313167
GO:0003925	G protein activity	19/3863	54/18639	0.351851851851852	1.69768746224868	0.00978361738474978	0.0549063354954492
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	11/3863	26/18639	0.423076923076923	2.04134889185368	0.0103477789422456	0.0573310986502287
GO:0050681	nuclear androgen receptor binding	11/3863	26/18639	0.423076923076923	2.04134889185368	0.0103477789422456	0.0573310986502287
GO:0052742	phosphatidylinositol kinase activity	11/3863	26/18639	0.423076923076923	2.04134889185368	0.0103477789422456	0.0573310986502287
GO:0004532	RNA exonuclease activity	15/3863	40/18639	0.375	1.80937742687031	0.0109550739247999	0.0604385858054641
GO:0140311	protein sequestering activity	13/3863	33/18639	0.393939393939394	1.90076012519709	0.0110181359713726	0.060530012804756
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	10/3863	23/18639	0.434782608695652	2.0978289007192	0.011485352657381	0.0625687412548539
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	10/3863	23/18639	0.434782608695652	2.0978289007192	0.011485352657381	0.0625687412548539
GO:0003697	single-stranded DNA binding	36/3863	121/18639	0.297520661157025	1.43553911553347	0.0117538774602275	0.063764785221734
GO:0001223	transcription coactivator binding	16/3863	44/18639	0.363636363636364	1.75454780787424	0.0121244448017057	0.065502187268966
GO:0008187	poly-pyrimidine tract binding	12/3863	30/18639	0.4	1.93000258866166	0.0125524311381438	0.0671760652962459
GO:0070566	adenylyltransferase activity	12/3863	30/18639	0.4	1.93000258866166	0.0125524311381438	0.0671760652962459
GO:0043024	ribosomal small subunit binding	9/3863	20/18639	0.45	2.17125291224437	0.0125890629280215	0.0671760652962459
GO:0140693	molecular condensate scaffold activity	17/3863	48/18639	0.354166666666667	1.70885645871085	0.0131573271104396	0.0699217955011933
GO:0032183	SUMO binding	8/3863	17/18639	0.470588235294118	2.27059128077843	0.0135356089851281	0.0716396865798242
GO:0019107	myristoyltransferase activity	6/3863	11/18639	0.545454545454545	2.63182171181136	0.013883949273167	0.0728907336841266
GO:0070990	snRNP binding	6/3863	11/18639	0.545454545454545	2.63182171181136	0.013883949273167	0.0728907336841266
GO:0004705	JUN kinase activity	7/3863	14/18639	0.5	2.41250323582708	0.014101833474346	0.0734423487343938
GO:0005545	1-phosphatidylinositol binding	7/3863	14/18639	0.5	2.41250323582708	0.014101833474346	0.0734423487343938
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	11/3863	27/18639	0.407407407407407	1.96574337734058	0.0142505490785451	0.0739211749014571
GO:1901981	phosphatidylinositol phosphate binding	51/3863	185/18639	0.275675675675676	1.33013691921277	0.0154666486515991	0.0799110180332618
GO:0001091	RNA polymerase II general transcription initiation factor binding	10/3863	24/18639	0.416666666666667	2.01041936318923	0.0160976654672321	0.0828425313768229
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	14/3863	38/18639	0.368421052631579	1.777633963241	0.0162481688845336	0.0829612387751479
GO:0042162	telomeric DNA binding	14/3863	38/18639	0.368421052631579	1.777633963241	0.0162481688845336	0.0829612387751479
GO:0051117	ATPase binding	26/3863	84/18639	0.30952380952381	1.49345438408343	0.0176841501171643	0.0899404822365151
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9/3863	21/18639	0.428571428571429	2.06785991642321	0.0180504325208964	0.0914461600864089
GO:0140566	histone reader activity	13/3863	35/18639	0.371428571428571	1.79214526090011	0.01881525124618	0.0949513841958385
GO:0141052	histone H3 demethylase activity	11/3863	28/18639	0.392857142857143	1.89553825672128	0.0191662010763646	0.0963490108163196
GO:0008525	phosphatidylcholine transporter activity	8/3863	18/18639	0.444444444444444	2.14444732073518	0.0200119202753811	0.100213539225178
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	46/3863	167/18639	0.275449101796407	1.32904369877899	0.0209088603277365	0.104303969910777
GO:0035251	UDP-glucosyltransferase activity	6/3863	12/18639	0.5	2.41250323582708	0.0229594429761499	0.111127118048131
GO:0043047	single-stranded telomeric DNA binding	6/3863	12/18639	0.5	2.41250323582708	0.0229594429761499	0.111127118048131
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	6/3863	12/18639	0.5	2.41250323582708	0.0229594429761499	0.111127118048131
GO:0070410	co-SMAD binding	6/3863	12/18639	0.5	2.41250323582708	0.0229594429761499	0.111127118048131
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	6/3863	12/18639	0.5	2.41250323582708	0.0229594429761499	0.111127118048131
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	6/3863	12/18639	0.5	2.41250323582708	0.0229594429761499	0.111127118048131
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	6/3863	12/18639	0.5	2.41250323582708	0.0229594429761499	0.111127118048131
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	6/3863	12/18639	0.5	2.41250323582708	0.0229594429761499	0.111127118048131
GO:0016410	N-acyltransferase activity	28/3863	94/18639	0.297872340425532	1.43723597027996	0.0237741172001434	0.114644076276247
GO:0034062	5'-3' RNA polymerase activity	9/3863	22/18639	0.409090909090909	1.97386628385852	0.0250464119041785	0.119891280511913
GO:0097747	RNA polymerase activity	9/3863	22/18639	0.409090909090909	1.97386628385852	0.0250464119041785	0.119891280511913
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	14/3863	40/18639	0.35	1.68875226507895	0.0258324009354666	0.122751043861232
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	14/3863	40/18639	0.35	1.68875226507895	0.0258324009354666	0.122751043861232
GO:0008276	protein methyltransferase activity	28/3863	95/18639	0.294736842105263	1.4221071705928	0.0272257981526474	0.128901778889989
GO:0008135	translation factor activity, RNA binding	25/3863	83/18639	0.301204819277108	1.45331520230547	0.0275232132358904	0.1298377667867
GO:0071889	14-3-3 protein binding	12/3863	33/18639	0.363636363636364	1.75454780787424	0.0279442384421338	0.131348008850752
GO:0140036	ubiquitin-modified protein reader activity	8/3863	19/18639	0.421052631578947	2.03158167227543	0.028415559496074	0.133082944114706
GO:0032266	phosphatidylinositol-3-phosphate binding	16/3863	48/18639	0.333333333333333	1.60833549055138	0.028562096362552	0.133289783025243
GO:0005112	Notch binding	10/3863	26/18639	0.384615384615385	1.85577171986698	0.0292012075814732	0.13578561525385
GO:0030145	manganese ion binding	21/3863	68/18639	0.308823529411765	1.49007552801084	0.031580506856539	0.14444129976452
GO:0180051	translation factor activity	25/3863	84/18639	0.297619047619048	1.43601383084945	0.0316923077777235	0.14444129976452
GO:0015923	mannosidase activity	7/3863	16/18639	0.4375	2.11094033134869	0.0319335020848186	0.14444129976452
GO:0030275	LRR domain binding	7/3863	16/18639	0.4375	2.11094033134869	0.0319335020848186	0.14444129976452
GO:0034450	ubiquitin-ubiquitin ligase activity	7/3863	16/18639	0.4375	2.11094033134869	0.0319335020848186	0.14444129976452
GO:0043023	ribosomal large subunit binding	7/3863	16/18639	0.4375	2.11094033134869	0.0319335020848186	0.14444129976452
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	7/3863	16/18639	0.4375	2.11094033134869	0.0319335020848186	0.14444129976452
GO:0140318	protein transporter activity	14/3863	41/18639	0.341463414634146	1.64756318544288	0.031950149256668	0.14444129976452
GO:0032452	histone demethylase activity	11/3863	30/18639	0.366666666666667	1.76916903960652	0.0325698454817033	0.146227375231647
GO:0035925	mRNA 3'-UTR AU-rich region binding	11/3863	30/18639	0.366666666666667	1.76916903960652	0.0325698454817033	0.146227375231647
GO:0042171	lysophosphatidic acid acyltransferase activity	9/3863	23/18639	0.391304347826087	1.88804601064728	0.0337642357056912	0.150355210618783
GO:0071617	lysophospholipid acyltransferase activity	9/3863	23/18639	0.391304347826087	1.88804601064728	0.0337642357056912	0.150355210618783
GO:0005543	phospholipid binding	120/3863	497/18639	0.241448692152918	1.16499150221026	0.0338356963988504	0.150355210618783
GO:0140666	annealing activity	6/3863	13/18639	0.461538461538462	2.22692606384038	0.0352959169418732	0.155780623248539
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	6/3863	13/18639	0.461538461538462	2.22692606384038	0.0352959169418732	0.155780623248539
GO:0051219	phosphoprotein binding	27/3863	93/18639	0.290322580645161	1.40080833048024	0.0356680596898286	0.156891262554584
GO:0005381	iron ion transmembrane transporter activity	5/3863	10/18639	0.5	2.41250323582708	0.0377858716115194	0.163268705555513
GO:0005528	FK506 binding	5/3863	10/18639	0.5	2.41250323582708	0.0377858716115194	0.163268705555513
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	5/3863	10/18639	0.5	2.41250323582708	0.0377858716115194	0.163268705555513
GO:0008641	ubiquitin-like modifier activating enzyme activity	5/3863	10/18639	0.5	2.41250323582708	0.0377858716115194	0.163268705555513
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	5/3863	10/18639	0.5	2.41250323582708	0.0377858716115194	0.163268705555513
GO:0005385	zinc ion transmembrane transporter activity	10/3863	27/18639	0.37037037037037	1.78703943394598	0.0379957125831954	0.163268705555513
GO:0008266	poly(U) RNA binding	10/3863	27/18639	0.37037037037037	1.78703943394598	0.0379957125831954	0.163268705555513
GO:0000149	SNARE binding	30/3863	106/18639	0.283018867924528	1.36556786933608	0.0387232879262245	0.164722264561552
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	8/3863	20/18639	0.4	1.93000258866166	0.0389665572081091	0.164722264561552
GO:0016505	peptidase activator activity involved in apoptotic process	8/3863	20/18639	0.4	1.93000258866166	0.0389665572081091	0.164722264561552
GO:0030742	GTP-dependent protein binding	8/3863	20/18639	0.4	1.93000258866166	0.0389665572081091	0.164722264561552
GO:0052745	inositol phosphate phosphatase activity	8/3863	20/18639	0.4	1.93000258866166	0.0389665572081091	0.164722264561552
GO:0140457	protein demethylase activity	11/3863	31/18639	0.354838709677419	1.71209907058696	0.0413004780201175	0.174023373405155
GO:0017069	snRNA binding	17/3863	54/18639	0.314814814814815	1.51898351885409	0.0419184585292204	0.175491424453521
GO:0051287	NAD binding	17/3863	54/18639	0.314814814814815	1.51898351885409	0.0419184585292204	0.175491424453521
GO:0061980	regulatory RNA binding	18/3863	58/18639	0.310344827586207	1.49741580154784	0.0423522171793048	0.176595230336335
GO:0003684	damaged DNA binding	22/3863	74/18639	0.297297297297297	1.43446138346475	0.042453384865801	0.176595230336335
GO:0097110	scaffold protein binding	21/3863	70/18639	0.3	1.44750194149625	0.0426209783376531	0.176727750941479
GO:0042578	phosphoric ester hydrolase activity	89/3863	363/18639	0.245179063360882	1.18299056743036	0.0433998467758519	0.179386033340188
GO:0000175	3'-5'-RNA exonuclease activity	12/3863	35/18639	0.342857142857143	1.65428793313857	0.0438486439512032	0.180097584935226
GO:0043015	gamma-tubulin binding	12/3863	35/18639	0.342857142857143	1.65428793313857	0.0438486439512032	0.180097584935226
GO:0140612	DNA damage sensor activity	9/3863	24/18639	0.375	1.80937742687031	0.0443641778487666	0.18164201119212
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	7/3863	17/18639	0.411764705882353	1.98676737068112	0.0448120272546019	0.18176093297661
GO:0016805	dipeptidase activity	7/3863	17/18639	0.411764705882353	1.98676737068112	0.0448120272546019	0.18176093297661
GO:0032977	membrane insertase activity	7/3863	17/18639	0.411764705882353	1.98676737068112	0.0448120272546019	0.18176093297661
GO:0016757	glycosyltransferase activity	67/3863	267/18639	0.250936329588015	1.21076941423531	0.0471227329388398	0.190316407823745
GO:0008375	acetylglucosaminyltransferase activity	14/3863	43/18639	0.325581395348837	1.57093233960833	0.0472136710653376	0.190316407823745
GO:0046625	sphingolipid binding	10/3863	28/18639	0.357142857142857	1.72321659701934	0.0484565523092126	0.194723552798132
GO:0140313	molecular sequestering activity	17/3863	55/18639	0.309090909090909	1.4913656366931	0.049339405166177	0.197661247773423
GO:0030983	mismatched DNA binding	6/3863	14/18639	0.428571428571429	2.06785991642321	0.0511914795425185	0.201973655649573
GO:0032454	histone H3K9 demethylase activity	6/3863	14/18639	0.428571428571429	2.06785991642321	0.0511914795425185	0.201973655649573
GO:0070742	C2H2 zinc finger domain binding	6/3863	14/18639	0.428571428571429	2.06785991642321	0.0511914795425185	0.201973655649573
GO:0098847	sequence-specific single stranded DNA binding	6/3863	14/18639	0.428571428571429	2.06785991642321	0.0511914795425185	0.201973655649573
GO:1990825	sequence-specific mRNA binding	6/3863	14/18639	0.428571428571429	2.06785991642321	0.0511914795425185	0.201973655649573
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	8/3863	21/18639	0.380952380952381	1.8380977034873	0.0518380185540862	0.202075150171917
GO:0035613	RNA stem-loop binding	8/3863	21/18639	0.380952380952381	1.8380977034873	0.0518380185540862	0.202075150171917
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	8/3863	21/18639	0.380952380952381	1.8380977034873	0.0518380185540862	0.202075150171917
GO:0140312	cargo adaptor activity	8/3863	21/18639	0.380952380952381	1.8380977034873	0.0518380185540862	0.202075150171917
GO:0016409	palmitoyltransferase activity	12/3863	36/18639	0.333333333333333	1.60833549055138	0.0537744029970323	0.2089978289616
GO:0015631	tubulin binding	93/3863	385/18639	0.241558441558442	1.16552104380217	0.0551227988781744	0.212098430485177
GO:0004177	aminopeptidase activity	13/3863	40/18639	0.325	1.5681271032876	0.055386686916252	0.212098430485177
GO:0030331	nuclear estrogen receptor binding	13/3863	40/18639	0.325	1.5681271032876	0.055386686916252	0.212098430485177
GO:0061791	GTPase motor activity	13/3863	40/18639	0.325	1.5681271032876	0.055386686916252	0.212098430485177
GO:1990606	membrane scission GTPase motor activity	13/3863	40/18639	0.325	1.5681271032876	0.055386686916252	0.212098430485177
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	33/3863	122/18639	0.270491803278689	1.30512470134907	0.0562345194995313	0.214424172578895
GO:0001046	core promoter sequence-specific DNA binding	14/3863	44/18639	0.318181818181818	1.53522933188996	0.0564880884750853	0.214424172578895
GO:0003954	NADH dehydrogenase activity	14/3863	44/18639	0.318181818181818	1.53522933188996	0.0564880884750853	0.214424172578895
GO:0004709	MAP kinase kinase kinase activity	9/3863	25/18639	0.36	1.7370023297955	0.056972215397029	0.215633210601546
GO:0002162	dystroglycan binding	5/3863	11/18639	0.454545454545455	2.1931847598428	0.0577041402268129	0.216515246614727
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	5/3863	11/18639	0.454545454545455	2.1931847598428	0.0577041402268129	0.216515246614727
GO:0034511	U3 snoRNA binding	5/3863	11/18639	0.454545454545455	2.1931847598428	0.0577041402268129	0.216515246614727
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	7/3863	18/18639	0.388888888888889	1.87639140564328	0.0605939135141062	0.225090155944762
GO:0070628	proteasome binding	7/3863	18/18639	0.388888888888889	1.87639140564328	0.0605939135141062	0.225090155944762
GO:1990381	ubiquitin-specific protease binding	7/3863	18/18639	0.388888888888889	1.87639140564328	0.0605939135141062	0.225090155944762
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	10/3863	29/18639	0.344827586206897	1.66379533505316	0.0606809867408691	0.225090155944762
GO:0001618	virus receptor activity	23/3863	81/18639	0.283950617283951	1.37006356602525	0.0621085591874374	0.229731091085351
GO:0001727	lipid kinase activity	13/3863	41/18639	0.317073170731707	1.52988010076839	0.0662679365439162	0.244421680963679
GO:0140035	ubiquitin-like protein reader activity	8/3863	22/18639	0.363636363636364	1.75454780787424	0.067147508068319	0.246966258488563
GO:0140272	exogenous protein binding	23/3863	82/18639	0.280487804878049	1.35335547375665	0.0700068236561375	0.25675742084589
GO:0004559	alpha-mannosidase activity	6/3863	15/18639	0.4	1.93000258866166	0.0707973817576335	0.256763763366125
GO:0031386	protein tag activity	6/3863	15/18639	0.4	1.93000258866166	0.0707973817576335	0.256763763366125
GO:0050700	CARD domain binding	6/3863	15/18639	0.4	1.93000258866166	0.0707973817576335	0.256763763366125
GO:0141047	molecular tag activity	6/3863	15/18639	0.4	1.93000258866166	0.0707973817576335	0.256763763366125
GO:0008143	poly(A) binding	9/3863	26/18639	0.346153846153846	1.67019454788028	0.0716745136523234	0.258504755610319
GO:0070006	metalloaminopeptidase activity	9/3863	26/18639	0.346153846153846	1.67019454788028	0.0716745136523234	0.258504755610319
GO:0031491	nucleosome binding	21/3863	74/18639	0.283783783783784	1.36925859330726	0.0726361427792057	0.261249331211397
GO:0008235	metalloexopeptidase activity	19/3863	66/18639	0.287878787878788	1.38901701456711	0.0750299486940883	0.269115683745738
GO:0016831	carboxy-lyase activity	11/3863	34/18639	0.323529411764706	1.56103150553517	0.0767207082660414	0.274424071874687
GO:0043531	ADP binding	12/3863	38/18639	0.315789473684211	1.52368625420658	0.0778990944346074	0.277875673846189
GO:0035198	miRNA binding	13/3863	42/18639	0.30952380952381	1.49345438408343	0.0784671412226921	0.277977025458634
GO:0048487	beta-tubulin binding	13/3863	42/18639	0.30952380952381	1.49345438408343	0.0784671412226921	0.277977025458634
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	14/3863	46/18639	0.304347826086957	1.46848023050344	0.0785680071956814	0.277977025458634
GO:0008301	DNA binding, bending	7/3863	19/18639	0.368421052631579	1.777633963241	0.0793646200246249	0.278524892916608
GO:0050145	nucleoside monophosphate kinase activity	7/3863	19/18639	0.368421052631579	1.777633963241	0.0793646200246249	0.278524892916608
GO:0097001	ceramide binding	7/3863	19/18639	0.368421052631579	1.777633963241	0.0793646200246249	0.278524892916608
GO:0004300	enoyl-CoA hydratase activity	5/3863	12/18639	0.416666666666667	2.01041936318923	0.0825217811201437	0.284132799647276
GO:0005527	macrolide binding	5/3863	12/18639	0.416666666666667	2.01041936318923	0.0825217811201437	0.284132799647276
GO:0035197	siRNA binding	5/3863	12/18639	0.416666666666667	2.01041936318923	0.0825217811201437	0.284132799647276
GO:0035259	nuclear glucocorticoid receptor binding	5/3863	12/18639	0.416666666666667	2.01041936318923	0.0825217811201437	0.284132799647276
GO:0035497	cAMP response element binding	5/3863	12/18639	0.416666666666667	2.01041936318923	0.0825217811201437	0.284132799647276
GO:1990459	transferrin receptor binding	5/3863	12/18639	0.416666666666667	2.01041936318923	0.0825217811201437	0.284132799647276
GO:1990817	poly(A) RNA polymerase activity	5/3863	12/18639	0.416666666666667	2.01041936318923	0.0825217811201437	0.284132799647276
GO:0042277	peptide binding	61/3863	249/18639	0.244979919678715	1.18202969787511	0.0827083955962502	0.284132799647276
GO:0042054	histone methyltransferase activity	19/3863	67/18639	0.283582089552239	1.36828541733476	0.0851864207056981	0.291875578312681
GO:0022853	active monoatomic ion transmembrane transporter activity	31/3863	118/18639	0.26271186440678	1.26758644594304	0.0868553592597355	0.296812802509647
GO:0004879	nuclear receptor activity	17/3863	59/18639	0.288135593220339	1.39025610200204	0.0881381607962178	0.300408076849936
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	9/3863	27/18639	0.333333333333333	1.60833549055138	0.0885139141868876	0.300901086870307
GO:0000049	tRNA binding	22/3863	80/18639	0.275	1.32687677970489	0.0899047655785134	0.304833345789647
GO:0070273	phosphatidylinositol-4-phosphate binding	10/3863	31/18639	0.32258064516129	1.5564537005336	0.0906584999182303	0.306590563359833
GO:0140938	histone H3 methyltransferase activity	14/3863	47/18639	0.297872340425532	1.43723597027996	0.0914356767059166	0.307962534022428
GO:0034061	DNA polymerase activity	11/3863	35/18639	0.314285714285714	1.51643060537702	0.0917870710770091	0.307962534022428
GO:0004712	protein serine/threonine/tyrosine kinase activity	13/3863	43/18639	0.302325581395349	1.45872288677916	0.0920103116242124	0.307962534022428
GO:0048156	tau protein binding	13/3863	43/18639	0.302325581395349	1.45872288677916	0.0920103116242124	0.307962534022428
GO:0005159	insulin-like growth factor receptor binding	6/3863	16/18639	0.375	1.80937742687031	0.0941157095613225	0.314201676535492
GO:0008013	beta-catenin binding	28/3863	106/18639	0.264150943396226	1.27453001138034	0.0943725597737408	0.314253383185193
GO:0008170	N-methyltransferase activity	26/3863	98/18639	0.26530612244898	1.2801037577858	0.0997426310337469	0.331261285276742
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	17/3863	60/18639	0.283333333333333	1.36708516696868	0.100243430414006	0.331261285276742
GO:0098531	ligand-modulated transcription factor activity	17/3863	60/18639	0.283333333333333	1.36708516696868	0.100243430414006	0.331261285276742
GO:0140664	ATP-dependent DNA damage sensor activity	7/3863	20/18639	0.35	1.68875226507895	0.101117423079672	0.333303505948691
GO:0019888	protein phosphatase regulator activity	28/3863	107/18639	0.261682242990654	1.26261851594688	0.103564571745748	0.340507758618595
GO:0035035	histone acetyltransferase binding	8/3863	24/18639	0.333333333333333	1.60833549055138	0.105245791068197	0.345163778263963
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	14/3863	48/18639	0.291666666666667	1.40729355423246	0.105540855442979	0.345261793434066
GO:0008168	methyltransferase activity	50/3863	204/18639	0.245098039215686	1.18259962540543	0.106426194655637	0.347113614898124
GO:0009055	electron transfer activity	30/3863	116/18639	0.258620689655172	1.24784650128987	0.106807196003196	0.347113614898124
GO:0019205	nucleobase-containing compound kinase activity	13/3863	44/18639	0.295454545454545	1.42557009389782	0.106906727783524	0.347113614898124
GO:0046875	ephrin receptor binding	9/3863	28/18639	0.321428571428571	1.55089493731741	0.107488454023681	0.347133817768853
GO:0032451	demethylase activity	12/3863	40/18639	0.3	1.44750194149625	0.10793936461683	0.347133817768853
GO:0071949	FAD binding	12/3863	40/18639	0.3	1.44750194149625	0.10793936461683	0.347133817768853
GO:0016279	protein-lysine N-methyltransferase activity	19/3863	69/18639	0.27536231884058	1.32862497045549	0.108076935698317	0.347133817768853
GO:0030515	snoRNA binding	10/3863	32/18639	0.3125	1.50781452239192	0.108448443957614	0.347133817768853
GO:0005484	SNAP receptor activity	11/3863	36/18639	0.305555555555556	1.47430753300544	0.108512645032199	0.347133817768853
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	5/3863	13/18639	0.384615384615385	1.85577171986698	0.112037946231563	0.354061665032754
GO:0005338	nucleotide-sugar transmembrane transporter activity	5/3863	13/18639	0.384615384615385	1.85577171986698	0.112037946231563	0.354061665032754
GO:0035673	oligopeptide transmembrane transporter activity	5/3863	13/18639	0.384615384615385	1.85577171986698	0.112037946231563	0.354061665032754
GO:0046975	histone H3K36 methyltransferase activity	5/3863	13/18639	0.384615384615385	1.85577171986698	0.112037946231563	0.354061665032754
GO:0097157	pre-mRNA intronic binding	5/3863	13/18639	0.384615384615385	1.85577171986698	0.112037946231563	0.354061665032754
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	17/3863	61/18639	0.278688524590164	1.34467393472329	0.113333498179583	0.357288655278009
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	64/3863	268/18639	0.238805970149254	1.1522403514398	0.114703771998224	0.360735051066879
GO:0016860	intramolecular oxidoreductase activity	15/3863	53/18639	0.283018867924528	1.36556786933608	0.118453866591225	0.371631166992227
GO:0016278	lysine N-methyltransferase activity	19/3863	70/18639	0.271428571428571	1.3096446137347	0.120820074437911	0.376022034826939
GO:0001217	DNA-binding transcription repressor activity	66/3863	278/18639	0.237410071942446	1.14550513355818	0.120884512481691	0.376022034826939
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	6/3863	17/18639	0.352941176470588	1.70294346058382	0.12100862718317	0.376022034826939
GO:0070403	NAD+ binding	6/3863	17/18639	0.352941176470588	1.70294346058382	0.12100862718317	0.376022034826939
GO:0008137	NADH dehydrogenase (ubiquinone) activity	12/3863	41/18639	0.292682926829268	1.4121970160939	0.125182714164242	0.387082215593119
GO:0005123	death receptor binding	7/3863	21/18639	0.333333333333333	1.60833549055138	0.125757125342465	0.387082215593119
GO:0051010	microtubule plus-end binding	7/3863	21/18639	0.333333333333333	1.60833549055138	0.125757125342465	0.387082215593119
GO:0070182	DNA polymerase binding	7/3863	21/18639	0.333333333333333	1.60833549055138	0.125757125342465	0.387082215593119
GO:0000030	mannosyltransferase activity	8/3863	25/18639	0.32	1.54400207092933	0.127962767854629	0.392942272987565
GO:0106222	lncRNA binding	9/3863	29/18639	0.310344827586207	1.49741580154784	0.128551814300946	0.393822264046664
GO:0002020	protease binding	34/3863	136/18639	0.25	1.20625161791354	0.1305540477728	0.399017300939404
GO:0001094	TFIID-class transcription factor complex binding	4/3863	10/18639	0.4	1.93000258866166	0.133939648764746	0.399543477357874
GO:0015643	toxic substance binding	4/3863	10/18639	0.4	1.93000258866166	0.133939648764746	0.399543477357874
GO:0015924	mannosyl-oligosaccharide mannosidase activity	4/3863	10/18639	0.4	1.93000258866166	0.133939648764746	0.399543477357874
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	4/3863	10/18639	0.4	1.93000258866166	0.133939648764746	0.399543477357874
GO:0031419	cobalamin binding	4/3863	10/18639	0.4	1.93000258866166	0.133939648764746	0.399543477357874
GO:0043422	protein kinase B binding	4/3863	10/18639	0.4	1.93000258866166	0.133939648764746	0.399543477357874
GO:0050815	phosphoserine residue binding	4/3863	10/18639	0.4	1.93000258866166	0.133939648764746	0.399543477357874
GO:0051864	histone H3K36 demethylase activity	4/3863	10/18639	0.4	1.93000258866166	0.133939648764746	0.399543477357874
GO:1990757	ubiquitin ligase activator activity	4/3863	10/18639	0.4	1.93000258866166	0.133939648764746	0.399543477357874
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	15/3863	54/18639	0.277777777777778	1.34027957545949	0.134101766209978	0.399543477357874
GO:0050661	NADP binding	15/3863	54/18639	0.277777777777778	1.34027957545949	0.134101766209978	0.399543477357874
GO:0004527	exonuclease activity	22/3863	84/18639	0.261904761904762	1.26369217114752	0.135752236769306	0.403537470944376
GO:0008173	RNA methyltransferase activity	18/3863	67/18639	0.26865671641791	1.29627039536977	0.138381202297101	0.41041531979687
GO:0031490	chromatin DNA binding	32/3863	128/18639	0.25	1.20625161791354	0.138959289695111	0.411193170870532
GO:0030276	clathrin binding	13/3863	46/18639	0.282608695652174	1.36358878546748	0.140710495300564	0.415430986125476
GO:0008174	mRNA methyltransferase activity	5/3863	14/18639	0.357142857142857	1.72321659701934	0.145841538836587	0.428635854549067
GO:0046030	inositol trisphosphate phosphatase activity	5/3863	14/18639	0.357142857142857	1.72321659701934	0.145841538836587	0.428635854549067
GO:0036002	pre-mRNA binding	16/3863	59/18639	0.271186440677966	1.30847633129604	0.146603434905527	0.429904667222965
GO:0003746	translation elongation factor activity	6/3863	18/18639	0.333333333333333	1.60833549055138	0.151215984017702	0.436548140113189
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	6/3863	18/18639	0.333333333333333	1.60833549055138	0.151215984017702	0.436548140113189
GO:0004706	JUN kinase kinase kinase activity	6/3863	18/18639	0.333333333333333	1.60833549055138	0.151215984017702	0.436548140113189
GO:0008308	voltage-gated monoatomic anion channel activity	6/3863	18/18639	0.333333333333333	1.60833549055138	0.151215984017702	0.436548140113189
GO:0017128	phospholipid scramblase activity	6/3863	18/18639	0.333333333333333	1.60833549055138	0.151215984017702	0.436548140113189
GO:0035615	clathrin adaptor activity	6/3863	18/18639	0.333333333333333	1.60833549055138	0.151215984017702	0.436548140113189
GO:0098641	cadherin binding involved in cell-cell adhesion	6/3863	18/18639	0.333333333333333	1.60833549055138	0.151215984017702	0.436548140113189
GO:0008157	protein phosphatase 1 binding	8/3863	26/18639	0.307692307692308	1.48461737589359	0.152979769722321	0.438125232201451
GO:0050750	low-density lipoprotein particle receptor binding	8/3863	26/18639	0.307692307692308	1.48461737589359	0.152979769722321	0.438125232201451
GO:0070412	R-SMAD binding	8/3863	26/18639	0.307692307692308	1.48461737589359	0.152979769722321	0.438125232201451
GO:0070034	telomerase RNA binding	7/3863	22/18639	0.318181818181818	1.53522933188996	0.153108280070399	0.438125232201451
GO:0003743	translation initiation factor activity	14/3863	51/18639	0.274509803921569	1.32451158045408	0.15517592526608	0.443068102404466
GO:0016741	transferase activity, transferring one-carbon groups	51/3863	215/18639	0.237209302325581	1.1445364188575	0.157315652383295	0.448194703288949
GO:0043495	protein-membrane adaptor activity	13/3863	47/18639	0.276595744680851	1.33457625811711	0.159550867116165	0.45357036896342
GO:0015399	primary active transmembrane transporter activity	40/3863	166/18639	0.240963855421687	1.16265216184437	0.163214904653311	0.462667450219131
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	16/3863	60/18639	0.266666666666667	1.28666839244111	0.16346161835699	0.462667450219131
GO:0019208	phosphatase regulator activity	29/3863	117/18639	0.247863247863248	1.19594177502539	0.164899585366407	0.465725076240915
GO:0016776	phosphotransferase activity, phosphate group as acceptor	11/3863	39/18639	0.282051282051282	1.36089926123579	0.168301271994409	0.474303584711515
GO:0008327	methyl-CpG binding	9/3863	31/18639	0.290322580645161	1.40080833048024	0.176552448720733	0.486544507460889
GO:0005225	volume-sensitive anion channel activity	4/3863	11/18639	0.363636363636364	1.75454780787424	0.177502796500709	0.486544507460889
GO:0008526	phosphatidylinositol transfer activity	4/3863	11/18639	0.363636363636364	1.75454780787424	0.177502796500709	0.486544507460889
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/3863	11/18639	0.363636363636364	1.75454780787424	0.177502796500709	0.486544507460889
GO:0019206	nucleoside kinase activity	4/3863	11/18639	0.363636363636364	1.75454780787424	0.177502796500709	0.486544507460889
GO:0034713	type I transforming growth factor beta receptor binding	4/3863	11/18639	0.363636363636364	1.75454780787424	0.177502796500709	0.486544507460889
GO:0035252	UDP-xylosyltransferase activity	4/3863	11/18639	0.363636363636364	1.75454780787424	0.177502796500709	0.486544507460889
GO:0042285	xylosyltransferase activity	4/3863	11/18639	0.363636363636364	1.75454780787424	0.177502796500709	0.486544507460889
GO:0045294	alpha-catenin binding	4/3863	11/18639	0.363636363636364	1.75454780787424	0.177502796500709	0.486544507460889
GO:0047676	arachidonate-CoA ligase activity	4/3863	11/18639	0.363636363636364	1.75454780787424	0.177502796500709	0.486544507460889
GO:0070697	activin receptor binding	4/3863	11/18639	0.363636363636364	1.75454780787424	0.177502796500709	0.486544507460889
GO:0140031	phosphorylation-dependent protein binding	4/3863	11/18639	0.363636363636364	1.75454780787424	0.177502796500709	0.486544507460889
GO:0180030	inositol phosphate kinase activity	4/3863	11/18639	0.363636363636364	1.75454780787424	0.177502796500709	0.486544507460889
GO:0019905	syntaxin binding	16/3863	61/18639	0.262295081967213	1.26557546797486	0.181284949975623	0.494284533796346
GO:0003887	DNA-directed DNA polymerase activity	7/3863	23/18639	0.304347826086957	1.46848023050344	0.182926687603363	0.494284533796346
GO:0005158	insulin receptor binding	7/3863	23/18639	0.304347826086957	1.46848023050344	0.182926687603363	0.494284533796346
GO:0008171	O-methyltransferase activity	7/3863	23/18639	0.304347826086957	1.46848023050344	0.182926687603363	0.494284533796346
GO:0008252	nucleotidase activity	5/3863	15/18639	0.333333333333333	1.60833549055138	0.183363617376064	0.494284533796346
GO:0140776	protein-containing complex destabilizing activity	5/3863	15/18639	0.333333333333333	1.60833549055138	0.183363617376064	0.494284533796346
GO:0141050	histone H3K deacetylase activity	5/3863	15/18639	0.333333333333333	1.60833549055138	0.183363617376064	0.494284533796346
GO:0141051	histone H4K deacetylase activity	5/3863	15/18639	0.333333333333333	1.60833549055138	0.183363617376064	0.494284533796346
GO:0120227	acyl-CoA binding	6/3863	19/18639	0.315789473684211	1.52368625420658	0.184378152014507	0.495992466782827
GO:0016790	thiolester hydrolase activity	12/3863	44/18639	0.272727272727273	1.31591085590568	0.185331949120823	0.496506579743438
GO:0043014	alpha-tubulin binding	12/3863	44/18639	0.272727272727273	1.31591085590568	0.185331949120823	0.496506579743438
GO:0019207	kinase regulator activity	66/3863	287/18639	0.229965156794425	1.10958336978806	0.187697471518446	0.501811309891205
GO:0019887	protein kinase regulator activity	59/3863	255/18639	0.231372549019608	1.11637404638273	0.188762238980953	0.503623842527051
GO:0005319	lipid transporter activity	42/3863	178/18639	0.235955056179775	1.13848467308694	0.19455182236224	0.518009146657743
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	10/3863	36/18639	0.277777777777778	1.34027957545949	0.197173647356742	0.521788798492843
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	10/3863	36/18639	0.277777777777778	1.34027957545949	0.197173647356742	0.521788798492843
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	10/3863	36/18639	0.277777777777778	1.34027957545949	0.197173647356742	0.521788798492843
GO:0022884	macromolecule transmembrane transporter activity	9/3863	32/18639	0.28125	1.35703307015273	0.20320184188891	0.535564368703159
GO:0043425	bHLH transcription factor binding	9/3863	32/18639	0.28125	1.35703307015273	0.20320184188891	0.535564368703159
GO:0008408	3'-5' exonuclease activity	15/3863	58/18639	0.258620689655172	1.24784650128987	0.207308102684692	0.545283130697916
GO:0051539	4 iron, 4 sulfur cluster binding	12/3863	45/18639	0.266666666666667	1.28666839244111	0.207944116876517	0.545853306800857
GO:0042626	ATPase-coupled transmembrane transporter activity	24/3863	98/18639	0.244897959183673	1.18163423795612	0.21017671692015	0.550603793621801
GO:0042625	ATPase-coupled ion transmembrane transporter activity	7/3863	24/18639	0.291666666666667	1.40729355423246	0.214912939117843	0.556922589461351
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	7/3863	24/18639	0.291666666666667	1.40729355423246	0.214912939117843	0.556922589461351
GO:0046961	proton-transporting ATPase activity, rotational mechanism	7/3863	24/18639	0.291666666666667	1.40729355423246	0.214912939117843	0.556922589461351
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	11/3863	41/18639	0.268292682926829	1.29451393141941	0.215402467597985	0.556922589461351
GO:0016877	ligase activity, forming carbon-sulfur bonds	11/3863	41/18639	0.268292682926829	1.29451393141941	0.215402467597985	0.556922589461351
GO:0070851	growth factor receptor binding	33/3863	139/18639	0.237410071942446	1.14550513355818	0.216665312654255	0.556922589461351
GO:0004540	RNA nuclease activity	29/3863	121/18639	0.239669421487603	1.15640650973529	0.218012679738801	0.556922589461351
GO:0016408	C-acyltransferase activity	6/3863	20/18639	0.3	1.44750194149625	0.220061321558008	0.556922589461351
GO:0015605	organophosphate ester transmembrane transporter activity	13/3863	50/18639	0.26	1.25450168263008	0.223090596741092	0.556922589461351
GO:0000062	fatty-acyl-CoA binding	5/3863	16/18639	0.3125	1.50781452239192	0.223930848200946	0.556922589461351
GO:0003688	DNA replication origin binding	5/3863	16/18639	0.3125	1.50781452239192	0.223930848200946	0.556922589461351
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/3863	16/18639	0.3125	1.50781452239192	0.223930848200946	0.556922589461351
GO:0004708	MAP kinase kinase activity	5/3863	16/18639	0.3125	1.50781452239192	0.223930848200946	0.556922589461351
GO:0008142	oxysterol binding	5/3863	16/18639	0.3125	1.50781452239192	0.223930848200946	0.556922589461351
GO:0015562	efflux transmembrane transporter activity	5/3863	16/18639	0.3125	1.50781452239192	0.223930848200946	0.556922589461351
GO:0017070	U6 snRNA binding	5/3863	16/18639	0.3125	1.50781452239192	0.223930848200946	0.556922589461351
GO:0031435	mitogen-activated protein kinase kinase kinase binding	5/3863	16/18639	0.3125	1.50781452239192	0.223930848200946	0.556922589461351
GO:0097027	ubiquitin-protein transferase activator activity	5/3863	16/18639	0.3125	1.50781452239192	0.223930848200946	0.556922589461351
GO:0003720	telomerase activity	4/3863	12/18639	0.333333333333333	1.60833549055138	0.224993304190991	0.556922589461351
GO:0005095	GTPase inhibitor activity	4/3863	12/18639	0.333333333333333	1.60833549055138	0.224993304190991	0.556922589461351
GO:0016801	hydrolase activity, acting on ether bonds	4/3863	12/18639	0.333333333333333	1.60833549055138	0.224993304190991	0.556922589461351
GO:0016803	ether hydrolase activity	4/3863	12/18639	0.333333333333333	1.60833549055138	0.224993304190991	0.556922589461351
GO:0017166	vinculin binding	4/3863	12/18639	0.333333333333333	1.60833549055138	0.224993304190991	0.556922589461351
GO:0034452	dynactin binding	4/3863	12/18639	0.333333333333333	1.60833549055138	0.224993304190991	0.556922589461351
GO:0045295	gamma-catenin binding	4/3863	12/18639	0.333333333333333	1.60833549055138	0.224993304190991	0.556922589461351
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/3863	12/18639	0.333333333333333	1.60833549055138	0.224993304190991	0.556922589461351
GO:0070679	inositol 1,4,5 trisphosphate binding	4/3863	12/18639	0.333333333333333	1.60833549055138	0.224993304190991	0.556922589461351
GO:0097677	STAT family protein binding	4/3863	12/18639	0.333333333333333	1.60833549055138	0.224993304190991	0.556922589461351
GO:0141221	histone deacetylase activity, hydrolytic mechanism	4/3863	12/18639	0.333333333333333	1.60833549055138	0.224993304190991	0.556922589461351
GO:0019210	kinase inhibitor activity	22/3863	90/18639	0.244444444444444	1.17944602640435	0.225565949943033	0.557280582212198
GO:0032934	sterol binding	17/3863	68/18639	0.25	1.20625161791354	0.231091566271113	0.569850794100358
GO:0050660	flavin adenine dinucleotide binding	21/3863	86/18639	0.244186046511628	1.17819925470625	0.233859526884055	0.575586207945256
GO:0008374	O-acyltransferase activity	14/3863	55/18639	0.254545454545455	1.22818346551197	0.236881992235209	0.581925196019324
GO:0016417	S-acyltransferase activity	8/3863	29/18639	0.275862068965517	1.33103626804253	0.239891662158256	0.588208934331543
GO:0016859	cis-trans isomerase activity	11/3863	42/18639	0.261904761904762	1.26369217114752	0.240785331044062	0.58929041544994
GO:0043539	protein serine/threonine kinase activator activity	18/3863	73/18639	0.246575342465753	1.1897276231476	0.241795373172853	0.590652112328433
GO:0016830	carbon-carbon lyase activity	13/3863	51/18639	0.254901960784314	1.22990361042165	0.246324563298333	0.599708179224146
GO:0003707	nuclear steroid receptor activity	7/3863	25/18639	0.28	1.35100181206316	0.248726894609093	0.599708179224146
GO:0015662	P-type ion transporter activity	7/3863	25/18639	0.28	1.35100181206316	0.248726894609093	0.599708179224146
GO:0019706	protein-cysteine S-palmitoyltransferase activity	7/3863	25/18639	0.28	1.35100181206316	0.248726894609093	0.599708179224146
GO:0019707	protein-cysteine S-acyltransferase activity	7/3863	25/18639	0.28	1.35100181206316	0.248726894609093	0.599708179224146
GO:0042974	nuclear retinoic acid receptor binding	7/3863	25/18639	0.28	1.35100181206316	0.248726894609093	0.599708179224146
GO:0140358	P-type transmembrane transporter activity	7/3863	25/18639	0.28	1.35100181206316	0.248726894609093	0.599708179224146
GO:0005109	frizzled binding	10/3863	38/18639	0.263157894736842	1.26973854517215	0.250488620177661	0.60283952582498
GO:0046982	protein heterodimerization activity	82/3863	369/18639	0.222222222222222	1.07222366036759	0.255082597221393	0.611788203009822
GO:0016758	hexosyltransferase activity	45/3863	197/18639	0.228426395939086	1.10215883870273	0.255146692960318	0.611788203009822
GO:0009931	calcium-dependent protein serine/threonine kinase activity	6/3863	21/18639	0.285714285714286	1.37857327761547	0.257783000044225	0.614713307797766
GO:0009975	cyclase activity	6/3863	21/18639	0.285714285714286	1.37857327761547	0.257783000044225	0.614713307797766
GO:0072542	protein phosphatase activator activity	6/3863	21/18639	0.285714285714286	1.37857327761547	0.257783000044225	0.614713307797766
GO:0052866	phosphatidylinositol phosphate phosphatase activity	9/3863	34/18639	0.264705882352941	1.27720759543786	0.260859693733694	0.619239891683218
GO:0019843	rRNA binding	16/3863	65/18639	0.246153846153846	1.18769390071487	0.261155761208014	0.619239891683218
GO:0030165	PDZ domain binding	20/3863	83/18639	0.240963855421687	1.16265216184437	0.261250636192462	0.619239891683218
GO:0003678	DNA helicase activity	18/3863	74/18639	0.243243243243243	1.17365022283479	0.261583671601974	0.619239891683218
GO:0004029	aldehyde dehydrogenase (NAD+) activity	5/3863	17/18639	0.294117647058824	1.41911955048652	0.266815106958353	0.621239524724771
GO:0004550	nucleoside diphosphate kinase activity	5/3863	17/18639	0.294117647058824	1.41911955048652	0.266815106958353	0.621239524724771
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	5/3863	17/18639	0.294117647058824	1.41911955048652	0.266815106958353	0.621239524724771
GO:0017110	nucleoside diphosphate phosphatase activity	5/3863	17/18639	0.294117647058824	1.41911955048652	0.266815106958353	0.621239524724771
GO:0019198	transmembrane receptor protein phosphatase activity	5/3863	17/18639	0.294117647058824	1.41911955048652	0.266815106958353	0.621239524724771
GO:0031489	myosin V binding	5/3863	17/18639	0.294117647058824	1.41911955048652	0.266815106958353	0.621239524724771
GO:0046965	nuclear retinoid X receptor binding	5/3863	17/18639	0.294117647058824	1.41911955048652	0.266815106958353	0.621239524724771
GO:1901567	fatty acid derivative binding	5/3863	17/18639	0.294117647058824	1.41911955048652	0.266815106958353	0.621239524724771
GO:1990226	histone methyltransferase binding	5/3863	17/18639	0.294117647058824	1.41911955048652	0.266815106958353	0.621239524724771
GO:0008200	ion channel inhibitor activity	11/3863	43/18639	0.255813953488372	1.23430398112083	0.267199795580547	0.621239524724771
GO:0030159	signaling receptor complex adaptor activity	13/3863	52/18639	0.25	1.20625161791354	0.270414453322709	0.627503997424157
GO:0015215	nucleotide transmembrane transporter activity	8/3863	30/18639	0.266666666666667	1.28666839244111	0.271992086273045	0.627503997424157
GO:0031210	phosphatidylcholine binding	8/3863	30/18639	0.266666666666667	1.28666839244111	0.271992086273045	0.627503997424157
GO:0051721	protein phosphatase 2A binding	8/3863	30/18639	0.266666666666667	1.28666839244111	0.271992086273045	0.627503997424157
GO:0003964	RNA-directed DNA polymerase activity	4/3863	13/18639	0.307692307692308	1.48461737589359	0.275195685506293	0.627503997424157
GO:0005035	death receptor activity	4/3863	13/18639	0.307692307692308	1.48461737589359	0.275195685506293	0.627503997424157
GO:0008253	5'-nucleotidase activity	4/3863	13/18639	0.307692307692308	1.48461737589359	0.275195685506293	0.627503997424157
GO:0045159	myosin II binding	4/3863	13/18639	0.307692307692308	1.48461737589359	0.275195685506293	0.627503997424157
GO:0046974	histone H3K9 methyltransferase activity	4/3863	13/18639	0.307692307692308	1.48461737589359	0.275195685506293	0.627503997424157
GO:0051011	microtubule minus-end binding	4/3863	13/18639	0.307692307692308	1.48461737589359	0.275195685506293	0.627503997424157
GO:0140410	monoatomic cation:bicarbonate symporter activity	4/3863	13/18639	0.307692307692308	1.48461737589359	0.275195685506293	0.627503997424157
GO:0008238	exopeptidase activity	24/3863	102/18639	0.235294117647059	1.13529564038921	0.276381877706487	0.629107001352877
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	10/3863	39/18639	0.256410256410256	1.23718114657799	0.278829085068437	0.633569753506292
GO:0004860	protein kinase inhibitor activity	20/3863	84/18639	0.238095238095238	1.14881106467956	0.280430230993784	0.636097841034681
GO:0005160	transforming growth factor beta receptor binding	7/3863	26/18639	0.269230769230769	1.29904020390689	0.284002151146325	0.641963195820338
GO:0034237	protein kinase A regulatory subunit binding	7/3863	26/18639	0.269230769230769	1.29904020390689	0.284002151146325	0.641963195820338
GO:0016248	channel inhibitor activity	11/3863	44/18639	0.25	1.20625161791354	0.294489077733788	0.66450326131409
GO:0004407	histone deacetylase activity	6/3863	22/18639	0.272727272727273	1.31591085590568	0.297036020034409	0.66450326131409
GO:0008093	cytoskeletal anchor activity	6/3863	22/18639	0.272727272727273	1.31591085590568	0.297036020034409	0.66450326131409
GO:0033558	protein lysine deacetylase activity	6/3863	22/18639	0.272727272727273	1.31591085590568	0.297036020034409	0.66450326131409
GO:0050321	tau-protein kinase activity	6/3863	22/18639	0.272727272727273	1.31591085590568	0.297036020034409	0.66450326131409
GO:0061133	endopeptidase activator activity	6/3863	22/18639	0.272727272727273	1.31591085590568	0.297036020034409	0.66450326131409
GO:1990782	protein tyrosine kinase binding	27/3863	117/18639	0.230769230769231	1.11346303192019	0.297685649602669	0.664814263778173
GO:0098631	cell adhesion mediator activity	18/3863	76/18639	0.236842105263158	1.14276469065493	0.302837285088651	0.675161207509287
GO:0016411	acylglycerol O-acyltransferase activity	8/3863	31/18639	0.258064516129032	1.24516296042688	0.305188481943415	0.678080893328201
GO:0070325	lipoprotein particle receptor binding	8/3863	31/18639	0.258064516129032	1.24516296042688	0.305188481943415	0.678080893328201
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	14/3863	58/18639	0.241379310344828	1.16465673453721	0.307211864465024	0.681413709597037
GO:0000400	four-way junction DNA binding	5/3863	18/18639	0.277777777777778	1.34027957545949	0.311276308089372	0.685755927465926
GO:0008409	5'-3' exonuclease activity	5/3863	18/18639	0.277777777777778	1.34027957545949	0.311276308089372	0.685755927465926
GO:0031690	adrenergic receptor binding	5/3863	18/18639	0.277777777777778	1.34027957545949	0.311276308089372	0.685755927465926
GO:0070064	proline-rich region binding	5/3863	18/18639	0.277777777777778	1.34027957545949	0.311276308089372	0.685755927465926
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	105/3863	484/18639	0.216942148760331	1.04674727174315	0.314171147562766	0.690964246835678
GO:0008320	protein transmembrane transporter activity	7/3863	27/18639	0.259259259259259	1.25092760376219	0.320359753302662	0.703386844519504
GO:0141110	transporter inhibitor activity	11/3863	45/18639	0.244444444444444	1.17944602640435	0.32248891801114	0.706869648569872
GO:0005161	platelet-derived growth factor receptor binding	4/3863	14/18639	0.285714285714286	1.37857327761547	0.326937344174175	0.70945403685796
GO:0008559	ABC-type xenobiotic transporter activity	4/3863	14/18639	0.285714285714286	1.37857327761547	0.326937344174175	0.70945403685796
GO:0015926	glucosidase activity	4/3863	14/18639	0.285714285714286	1.37857327761547	0.326937344174175	0.70945403685796
GO:0016530	metallochaperone activity	4/3863	14/18639	0.285714285714286	1.37857327761547	0.326937344174175	0.70945403685796
GO:0032036	myosin heavy chain binding	4/3863	14/18639	0.285714285714286	1.37857327761547	0.326937344174175	0.70945403685796
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	4/3863	14/18639	0.285714285714286	1.37857327761547	0.326937344174175	0.70945403685796
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	21/3863	91/18639	0.230769230769231	1.11346303192019	0.32801842138644	0.709616747789083
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	16/3863	68/18639	0.235294117647059	1.13529564038921	0.328102367257318	0.709616747789083
GO:0045309	protein phosphorylated amino acid binding	14/3863	59/18639	0.23728813559322	1.14491678988404	0.331854660941317	0.716541904719062
GO:0016853	isomerase activity	40/3863	180/18639	0.222222222222222	1.07222366036759	0.337213161435412	0.718150279939515
GO:0140103	catalytic activity, acting on a glycoprotein	6/3863	23/18639	0.260869565217391	1.25869734043152	0.337309902068896	0.718150279939515
GO:0031369	translation initiation factor binding	8/3863	32/18639	0.25	1.20625161791354	0.339184028628249	0.718150279939515
GO:0120015	sterol transfer activity	8/3863	32/18639	0.25	1.20625161791354	0.339184028628249	0.718150279939515
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0004382	GDP phosphatase activity	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0004445	inositol-polyphosphate 5-phosphatase activity	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0008140	cAMP response element binding protein binding	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0008239	dipeptidyl-peptidase activity	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0016783	sulfurtransferase activity	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0016868	intramolecular phosphotransferase activity	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0030957	Tat protein binding	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0031996	thioesterase binding	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0042975	peroxisome proliferator activated receptor binding	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0043121	neurotrophin binding	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0043208	glycosphingolipid binding	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0045322	unmethylated CpG binding	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0047429	nucleoside triphosphate diphosphatase activity	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0070513	death domain binding	3/3863	10/18639	0.3	1.44750194149625	0.344182622643823	0.718150279939515
GO:0098632	cell-cell adhesion mediator activity	13/3863	55/18639	0.236363636363636	1.14045607511825	0.346634645611074	0.72210929373699
GO:0043178	alcohol binding	21/3863	92/18639	0.228260869565217	1.10136017287758	0.348024207180196	0.723845874997789
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	5/3863	19/18639	0.263157894736842	1.26973854517215	0.35659707811611	0.73400886066061
GO:0005229	intracellularly calcium-gated chloride channel activity	5/3863	19/18639	0.263157894736842	1.26973854517215	0.35659707811611	0.73400886066061
GO:0042800	histone H3K4 methyltransferase activity	5/3863	19/18639	0.263157894736842	1.26973854517215	0.35659707811611	0.73400886066061
GO:0043395	heparan sulfate proteoglycan binding	5/3863	19/18639	0.263157894736842	1.26973854517215	0.35659707811611	0.73400886066061
GO:0046624	sphingolipid transporter activity	5/3863	19/18639	0.263157894736842	1.26973854517215	0.35659707811611	0.73400886066061
GO:0141147	intracellularly calcium-gated channel activity	5/3863	19/18639	0.263157894736842	1.26973854517215	0.35659707811611	0.73400886066061
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	14/3863	60/18639	0.233333333333333	1.12583484338597	0.35691406218932	0.73400886066061
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	7/3863	28/18639	0.25	1.20625161791354	0.357420597280205	0.73400886066061
GO:0008017	microtubule binding	60/3863	276/18639	0.217391304347826	1.0489144503596	0.360846445848228	0.739877279518728
GO:0019239	deaminase activity	8/3863	33/18639	0.242424242424242	1.16969853858283	0.373683031692107	0.76458876162682
GO:0001216	DNA-binding transcription activator activity	105/3863	491/18639	0.213849287169043	1.03182419454926	0.375102679598808	0.76458876162682
GO:0004622	lysophospholipase activity	6/3863	24/18639	0.25	1.20625161791354	0.378108889719247	0.76458876162682
GO:0060229	lipase activator activity	6/3863	24/18639	0.25	1.20625161791354	0.378108889719247	0.76458876162682
GO:0070840	dynein complex binding	6/3863	24/18639	0.25	1.20625161791354	0.378108889719247	0.76458876162682
GO:0004467	long-chain fatty acid-CoA ligase activity	4/3863	15/18639	0.266666666666667	1.28666839244111	0.379145972100761	0.76458876162682
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/3863	15/18639	0.266666666666667	1.28666839244111	0.379145972100761	0.76458876162682
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/3863	15/18639	0.266666666666667	1.28666839244111	0.379145972100761	0.76458876162682
GO:0031005	filamin binding	4/3863	15/18639	0.266666666666667	1.28666839244111	0.379145972100761	0.76458876162682
GO:0120283	protein serine/threonine kinase binding	4/3863	15/18639	0.266666666666667	1.28666839244111	0.379145972100761	0.76458876162682
GO:0140359	ABC-type transporter activity	11/3863	47/18639	0.234042553191489	1.1292568337914	0.379945413803804	0.76458876162682
GO:1990518	single-stranded 3'-5' DNA helicase activity	11/3863	47/18639	0.234042553191489	1.1292568337914	0.379945413803804	0.76458876162682
GO:0044325	transmembrane transporter binding	30/3863	136/18639	0.220588235294118	1.06433966286489	0.383015468608877	0.76957737674191
GO:0005080	protein kinase C binding	12/3863	52/18639	0.230769230769231	1.11346303192019	0.390257746513051	0.782920779599371
GO:0015095	magnesium ion transmembrane transporter activity	5/3863	20/18639	0.25	1.20625161791354	0.40210899696881	0.792563271081588
GO:0016004	phospholipase activator activity	5/3863	20/18639	0.25	1.20625161791354	0.40210899696881	0.792563271081588
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	5/3863	20/18639	0.25	1.20625161791354	0.40210899696881	0.792563271081588
GO:0031418	L-ascorbic acid binding	5/3863	20/18639	0.25	1.20625161791354	0.40210899696881	0.792563271081588
GO:0017022	myosin binding	17/3863	76/18639	0.223684210526316	1.07927776339632	0.40578561048433	0.792563271081588
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:0000099	sulfur amino acid transmembrane transporter activity	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:0008432	JUN kinase binding	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:0019215	intermediate filament binding	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:0032050	clathrin heavy chain binding	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:0032404	mismatch repair complex binding	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:0034056	estrogen response element binding	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:0043522	leucine zipper domain binding	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:0048185	activin binding	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:1900750	oligopeptide binding	3/3863	11/18639	0.272727272727273	1.31591085590568	0.406687557447491	0.792563271081588
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	8/3863	34/18639	0.235294117647059	1.13529564038921	0.40839790491008	0.792563271081588
GO:0030332	cyclin binding	8/3863	34/18639	0.235294117647059	1.13529564038921	0.40839790491008	0.792563271081588
GO:0036121	double-stranded DNA helicase activity	11/3863	48/18639	0.229166666666667	1.10573064975408	0.409064914106626	0.792563271081588
GO:0043138	3'-5' DNA helicase activity	11/3863	48/18639	0.229166666666667	1.10573064975408	0.409064914106626	0.792563271081588
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	19/3863	86/18639	0.22093023255814	1.06598980187708	0.418721161798682	0.806944087486393
GO:0019211	phosphatase activator activity	6/3863	25/18639	0.24	1.158001553197	0.418966361859295	0.806944087486393
GO:0047617	fatty acyl-CoA hydrolase activity	6/3863	25/18639	0.24	1.158001553197	0.418966361859295	0.806944087486393
GO:0120020	cholesterol transfer activity	6/3863	25/18639	0.24	1.158001553197	0.418966361859295	0.806944087486393
GO:0000217	DNA secondary structure binding	9/3863	39/18639	0.230769230769231	1.11346303192019	0.419804146424837	0.80736336579784
GO:0019209	kinase activator activity	32/3863	148/18639	0.216216216216216	1.04324464251982	0.425749236527473	0.817589241827095
GO:0035401	histone H3Y41 kinase activity	25/3863	115/18639	0.217391304347826	1.0489144503596	0.430414084976641	0.822597389219516
GO:0140801	histone H2AXY142 kinase activity	25/3863	115/18639	0.217391304347826	1.0489144503596	0.430414084976641	0.822597389219516
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	4/3863	16/18639	0.25	1.20625161791354	0.430884346734032	0.822597389219516
GO:0022858	alanine transmembrane transporter activity	4/3863	16/18639	0.25	1.20625161791354	0.430884346734032	0.822597389219516
GO:0033612	receptor serine/threonine kinase binding	7/3863	30/18639	0.233333333333333	1.12583484338597	0.432197409672916	0.823896086960669
GO:0140101	catalytic activity, acting on a tRNA	30/3863	139/18639	0.215827338129496	1.04136830323471	0.434465872889457	0.827009600149229
GO:0015485	cholesterol binding	12/3863	54/18639	0.222222222222222	1.07222366036759	0.445887461800116	0.846320572750118
GO:0001846	opsonin binding	5/3863	21/18639	0.238095238095238	1.14881106467956	0.447210871007743	0.846320572750118
GO:0010314	phosphatidylinositol-5-phosphate binding	5/3863	21/18639	0.238095238095238	1.14881106467956	0.447210871007743	0.846320572750118
GO:1904047	S-adenosyl-L-methionine binding	5/3863	21/18639	0.238095238095238	1.14881106467956	0.447210871007743	0.846320572750118
GO:0004713	protein tyrosine kinase activity	30/3863	140/18639	0.214285714285714	1.0339299582116	0.451722967214733	0.853618727595911
GO:0008194	UDP-glycosyltransferase activity	31/3863	145/18639	0.213793103448276	1.03155310773296	0.455495885831888	0.859500932395824
GO:0016289	acyl-CoA hydrolase activity	6/3863	26/18639	0.230769230769231	1.11346303192019	0.459455625073186	0.863425005619124
GO:0120014	phospholipid transfer activity	6/3863	26/18639	0.230769230769231	1.11346303192019	0.459455625073186	0.863425005619124
GO:0004715	non-membrane spanning protein tyrosine kinase activity	10/3863	45/18639	0.222222222222222	1.07222366036759	0.46022807519176	0.863425005619124
GO:0042605	peptide antigen binding	10/3863	45/18639	0.222222222222222	1.07222366036759	0.46022807519176	0.863425005619124
GO:0051213	dioxygenase activity	20/3863	93/18639	0.21505376344086	1.03763580035573	0.467085107906496	0.865380520213308
GO:0004000	adenosine deaminase activity	3/3863	12/18639	0.25	1.20625161791354	0.467252308532992	0.865380520213308
GO:0005025	transforming growth factor beta receptor activity, type I	3/3863	12/18639	0.25	1.20625161791354	0.467252308532992	0.865380520213308
GO:0005026	transforming growth factor beta receptor activity, type II	3/3863	12/18639	0.25	1.20625161791354	0.467252308532992	0.865380520213308
GO:0016361	activin receptor activity, type I	3/3863	12/18639	0.25	1.20625161791354	0.467252308532992	0.865380520213308
GO:0016362	activin receptor activity, type II	3/3863	12/18639	0.25	1.20625161791354	0.467252308532992	0.865380520213308
GO:0016423	tRNA (guanine) methyltransferase activity	3/3863	12/18639	0.25	1.20625161791354	0.467252308532992	0.865380520213308
GO:0017002	activin receptor activity	3/3863	12/18639	0.25	1.20625161791354	0.467252308532992	0.865380520213308
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	3/3863	12/18639	0.25	1.20625161791354	0.467252308532992	0.865380520213308
GO:0072349	modified amino acid transmembrane transporter activity	7/3863	31/18639	0.225806451612903	1.08951759037352	0.469241680260688	0.867830493891215
GO:0005496	steroid binding	23/3863	108/18639	0.212962962962963	1.02754767451894	0.479734692719308	0.885226103169489
GO:0004549	tRNA-specific ribonuclease activity	4/3863	17/18639	0.235294117647059	1.13529564038921	0.481367189741934	0.885226103169489
GO:0015278	intracellularly gated calcium channel activity	4/3863	17/18639	0.235294117647059	1.13529564038921	0.481367189741934	0.885226103169489
GO:0048038	quinone binding	4/3863	17/18639	0.235294117647059	1.13529564038921	0.481367189741934	0.885226103169489
GO:0001530	lipopolysaccharide binding	9/3863	41/18639	0.219512195121951	1.05914776207042	0.484406961507749	0.887319170791936
GO:0120013	lipid transfer activity	14/3863	65/18639	0.215384615384615	1.03923216312551	0.48454986976426	0.887319170791936
GO:0160215	deacylase activity	14/3863	65/18639	0.215384615384615	1.03923216312551	0.48454986976426	0.887319170791936
GO:0016829	lyase activity	42/3863	200/18639	0.21	1.01325135904737	0.489851198158546	0.892296636206562
GO:0004180	carboxypeptidase activity	10/3863	46/18639	0.217391304347826	1.0489144503596	0.490560633424397	0.892296636206562
GO:0030291	protein serine/threonine kinase inhibitor activity	10/3863	46/18639	0.217391304347826	1.0489144503596	0.490560633424397	0.892296636206562
GO:0008649	rRNA methyltransferase activity	5/3863	22/18639	0.227272727272727	1.0965923799214	0.49137994482343	0.892296636206562
GO:0008970	phospholipase A1 activity	5/3863	22/18639	0.227272727272727	1.0965923799214	0.49137994482343	0.892296636206562
GO:0033691	sialic acid binding	5/3863	22/18639	0.227272727272727	1.0965923799214	0.49137994482343	0.892296636206562
GO:0004683	calcium/calmodulin-dependent protein kinase activity	6/3863	27/18639	0.222222222222222	1.07222366036759	0.499197302721908	0.903970637196
GO:0023026	MHC class II protein complex binding	6/3863	27/18639	0.222222222222222	1.07222366036759	0.499197302721908	0.903970637196
GO:0016836	hydro-lyase activity	13/3863	61/18639	0.213114754098361	1.02828006772957	0.505589368799779	0.914274108579601
GO:0022829	wide pore channel activity	8/3863	37/18639	0.216216216216216	1.04324464251982	0.511199531907615	0.921858435656115
GO:0042805	actinin binding	8/3863	37/18639	0.216216216216216	1.04324464251982	0.511199531907615	0.921858435656115
GO:0019894	kinesin binding	9/3863	42/18639	0.214285714285714	1.0339299582116	0.516078457993951	0.929369505267115
GO:0030295	protein kinase activator activity	29/3863	139/18639	0.20863309352518	1.00665602646022	0.517735629023421	0.931035180741395
GO:0001784	phosphotyrosine residue binding	10/3863	47/18639	0.212765957446809	1.02659712162854	0.52045663872726	0.931035180741395
GO:0061749	forked DNA-dependent helicase activity	10/3863	47/18639	0.212765957446809	1.02659712162854	0.52045663872726	0.931035180741395
GO:0016209	antioxidant activity	18/3863	86/18639	0.209302325581395	1.0098850754625	0.524082234228678	0.931035180741395
GO:0005172	vascular endothelial growth factor receptor binding	3/3863	13/18639	0.230769230769231	1.11346303192019	0.524869295441002	0.931035180741395
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/3863	13/18639	0.230769230769231	1.11346303192019	0.524869295441002	0.931035180741395
GO:0019855	calcium channel inhibitor activity	3/3863	13/18639	0.230769230769231	1.11346303192019	0.524869295441002	0.931035180741395
GO:0035325	Toll-like receptor binding	3/3863	13/18639	0.230769230769231	1.11346303192019	0.524869295441002	0.931035180741395
GO:0070123	transforming growth factor beta receptor activity, type III	3/3863	13/18639	0.230769230769231	1.11346303192019	0.524869295441002	0.931035180741395
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/3863	13/18639	0.230769230769231	1.11346303192019	0.524869295441002	0.931035180741395
GO:0089720	caspase binding	3/3863	13/18639	0.230769230769231	1.11346303192019	0.524869295441002	0.931035180741395
GO:0015932	nucleobase-containing compound transmembrane transporter activity	12/3863	57/18639	0.210526315789474	1.01579083613772	0.528113759595006	0.933712975668135
GO:0070279	vitamin B6 binding	12/3863	57/18639	0.210526315789474	1.01579083613772	0.528113759595006	0.933712975668135
GO:0000900	mRNA regulatory element binding translation repressor activity	4/3863	18/18639	0.222222222222222	1.07222366036759	0.529964584499809	0.933712975668135
GO:0017075	syntaxin-1 binding	4/3863	18/18639	0.222222222222222	1.07222366036759	0.529964584499809	0.933712975668135
GO:0050811	GABA receptor binding	4/3863	18/18639	0.222222222222222	1.07222366036759	0.529964584499809	0.933712975668135
GO:0017134	fibroblast growth factor binding	5/3863	23/18639	0.217391304347826	1.0489144503596	0.534177178921911	0.938594719239309
GO:0140102	catalytic activity, acting on a rRNA	5/3863	23/18639	0.217391304347826	1.0489144503596	0.534177178921911	0.938594719239309
GO:1902936	phosphatidylinositol bisphosphate binding	23/3863	111/18639	0.207207207207207	0.999776115748158	0.538248004197219	0.944472913025309
GO:0004518	nuclease activity	43/3863	209/18639	0.205741626794258	0.99270468077095	0.549279674482472	0.960806531693062
GO:0051015	actin filament binding	43/3863	209/18639	0.205741626794258	0.99270468077095	0.549279674482472	0.960806531693062
GO:0009378	four-way junction helicase activity	10/3863	48/18639	0.208333333333333	1.00520968159462	0.549770250469532	0.960806531693062
GO:0051018	protein kinase A binding	11/3863	53/18639	0.207547169811321	1.00141643751313	0.55230338362274	0.96264927105329
GO:1901505	carbohydrate derivative transmembrane transporter activity	11/3863	53/18639	0.207547169811321	1.00141643751313	0.55230338362274	0.96264927105329
GO:0017116	single-stranded DNA helicase activity	12/3863	58/18639	0.206896551724138	0.998277201031894	0.554714628816312	0.96555942074711
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	25/3863	122/18639	0.204918032786885	0.98873083435536	0.561456417933339	0.975989661080383
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	27/3863	132/18639	0.204545454545455	0.986933141929259	0.565314419115405	0.978783972957999
GO:0004181	metallocarboxypeptidase activity	6/3863	29/18639	0.206896551724138	0.998277201031894	0.575180418512499	0.978783972957999
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	6/3863	29/18639	0.206896551724138	0.998277201031894	0.575180418512499	0.978783972957999
GO:0051861	glycolipid binding	6/3863	29/18639	0.206896551724138	0.998277201031894	0.575180418512499	0.978783972957999
GO:0097472	cyclin-dependent protein kinase activity	6/3863	29/18639	0.206896551724138	0.998277201031894	0.575180418512499	0.978783972957999
GO:0030552	cAMP binding	5/3863	24/18639	0.208333333333333	1.00520968159462	0.575247781343664	0.978783972957999
GO:0050431	transforming growth factor beta binding	5/3863	24/18639	0.208333333333333	1.00520968159462	0.575247781343664	0.978783972957999
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	5/3863	24/18639	0.208333333333333	1.00520968159462	0.575247781343664	0.978783972957999
GO:0008175	tRNA methyltransferase activity	7/3863	34/18639	0.205882352941176	0.993383685340561	0.575616947084021	0.978783972957999
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/3863	19/18639	0.210526315789474	1.01579083613772	0.576195919535463	0.978783972957999
GO:0031420	alkali metal ion binding	4/3863	19/18639	0.210526315789474	1.01579083613772	0.576195919535463	0.978783972957999
GO:0070003	threonine-type peptidase activity	4/3863	19/18639	0.210526315789474	1.01579083613772	0.576195919535463	0.978783972957999
GO:0016874	ligase activity	34/3863	167/18639	0.203592814371257	0.9823366469236	0.577433323563406	0.978783972957999
GO:0035254	glutamate receptor binding	10/3863	49/18639	0.204081632653061	0.984695198296766	0.578371286362507	0.978783972957999
GO:0015386	potassium:proton antiporter activity	3/3863	14/18639	0.214285714285714	1.0339299582116	0.578850736695591	0.978783972957999
GO:0034236	protein kinase A catalytic subunit binding	3/3863	14/18639	0.214285714285714	1.0339299582116	0.578850736695591	0.978783972957999
GO:0042043	neurexin family protein binding	3/3863	14/18639	0.214285714285714	1.0339299582116	0.578850736695591	0.978783972957999
GO:0042813	Wnt receptor activity	3/3863	14/18639	0.214285714285714	1.0339299582116	0.578850736695591	0.978783972957999
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	3/3863	14/18639	0.214285714285714	1.0339299582116	0.578850736695591	0.978783972957999
GO:0071933	Arp2/3 complex binding	3/3863	14/18639	0.214285714285714	1.0339299582116	0.578850736695591	0.978783972957999
GO:0098821	BMP receptor activity	3/3863	14/18639	0.214285714285714	1.0339299582116	0.578850736695591	0.978783972957999
GO:0070888	E-box binding	12/3863	59/18639	0.203389830508475	0.981357248472032	0.580737764564142	0.98070112770754
GO:0016835	carbon-oxygen lyase activity	16/3863	79/18639	0.20253164556962	0.977216500588183	0.585841705023264	0.988038730492604
GO:0005516	calmodulin binding	42/3863	207/18639	0.202898550724638	0.978986820335626	0.589385859908443	0.992730128849668
GO:0032813	tumor necrosis factor receptor superfamily binding	10/3863	50/18639	0.2	0.965001294330831	0.606145869245486	1
GO:0050997	quaternary ammonium group binding	8/3863	40/18639	0.2	0.965001294330831	0.607388671826708	1
GO:0001848	complement binding	5/3863	25/18639	0.2	0.965001294330831	0.614318136214757	1
GO:0015645	fatty acid ligase activity	5/3863	25/18639	0.2	0.965001294330831	0.614318136214757	1
GO:0120515	fatty acid-CoA ligase activity	5/3863	25/18639	0.2	0.965001294330831	0.614318136214757	1
GO:0000339	RNA cap binding	4/3863	20/18639	0.2	0.965001294330831	0.619717650177126	1
GO:0042288	MHC class I protein binding	4/3863	20/18639	0.2	0.965001294330831	0.619717650177126	1
GO:0140939	histone H4 methyltransferase activity	4/3863	20/18639	0.2	0.965001294330831	0.619717650177126	1
GO:0005041	low-density lipoprotein particle receptor activity	3/3863	15/18639	0.2	0.965001294330831	0.628776927844298	1
GO:0015929	hexosaminidase activity	3/3863	15/18639	0.2	0.965001294330831	0.628776927844298	1
GO:0016846	carbon-sulfur lyase activity	3/3863	15/18639	0.2	0.965001294330831	0.628776927844298	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	3/3863	15/18639	0.2	0.965001294330831	0.628776927844298	1
GO:0030170	pyridoxal phosphate binding	11/3863	56/18639	0.196428571428571	0.947769128360638	0.631672076013153	1
GO:0042169	SH2 domain binding	8/3863	41/18639	0.195121951219512	0.941464677395933	0.637202419782819	1
GO:0016878	acid-thiol ligase activity	6/3863	31/18639	0.193548387096774	0.933872220320159	0.644930448433204	1
GO:0017147	Wnt-protein binding	6/3863	31/18639	0.193548387096774	0.933872220320159	0.644930448433204	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0004935	adrenergic receptor activity	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0005031	tumor necrosis factor receptor activity	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0005131	growth hormone receptor binding	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0008190	eukaryotic initiation factor 4E binding	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0015203	polyamine transmembrane transporter activity	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0015279	store-operated calcium channel activity	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0016427	tRNA (cytidine) methyltransferase activity	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0019911	structural constituent of myelin sheath	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0031434	mitogen-activated protein kinase kinase binding	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0032356	oxidized DNA binding	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0032395	MHC class II receptor activity	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0033204	ribonuclease P RNA binding	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0043295	glutathione binding	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0097177	mitochondrial ribosome binding	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:1990763	arrestin family protein binding	2/3863	10/18639	0.2	0.965001294330831	0.645763671713374	1
GO:0004529	DNA exonuclease activity	5/3863	26/18639	0.192307692307692	0.927885859933491	0.651190162677036	1
GO:0008198	ferrous iron binding	5/3863	26/18639	0.192307692307692	0.927885859933491	0.651190162677036	1
GO:0015216	purine nucleotide transmembrane transporter activity	5/3863	26/18639	0.192307692307692	0.927885859933491	0.651190162677036	1
GO:0030247	polysaccharide binding	5/3863	26/18639	0.192307692307692	0.927885859933491	0.651190162677036	1
GO:0051139	metal cation:proton antiporter activity	5/3863	26/18639	0.192307692307692	0.927885859933491	0.651190162677036	1
GO:0050840	extracellular matrix binding	13/3863	67/18639	0.194029850746269	0.936195285544836	0.652973311124129	1
GO:0008373	sialyltransferase activity	4/3863	21/18639	0.19047619047619	0.919048851743648	0.660307480569923	1
GO:0005504	fatty acid binding	9/3863	47/18639	0.191489361702128	0.923937409465689	0.661867814002902	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	17/3863	88/18639	0.193181818181818	0.932103522933189	0.669083457949018	1
GO:0019213	deacetylase activity	7/3863	37/18639	0.189189189189189	0.91283906220484	0.67062625157893	1
GO:0005024	transforming growth factor beta receptor activity	3/3863	16/18639	0.1875	0.904688713435154	0.674444446562052	1
GO:0005149	interleukin-1 receptor binding	3/3863	16/18639	0.1875	0.904688713435154	0.674444446562052	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/3863	16/18639	0.1875	0.904688713435154	0.674444446562052	1
GO:0008296	3'-5'-DNA exonuclease activity	3/3863	16/18639	0.1875	0.904688713435154	0.674444446562052	1
GO:0015385	sodium:proton antiporter activity	3/3863	16/18639	0.1875	0.904688713435154	0.674444446562052	1
GO:0016722	oxidoreductase activity, acting on metal ions	3/3863	16/18639	0.1875	0.904688713435154	0.674444446562052	1
GO:0015106	bicarbonate transmembrane transporter activity	6/3863	32/18639	0.1875	0.904688713435154	0.677070285136766	1
GO:0005544	calcium-dependent phospholipid binding	10/3863	53/18639	0.188679245283019	0.910378579557388	0.683619419770641	1
GO:0004364	glutathione transferase activity	5/3863	27/18639	0.185185185185185	0.893519716972992	0.685733994485019	1
GO:0016405	CoA-ligase activity	5/3863	27/18639	0.185185185185185	0.893519716972992	0.685733994485019	1
GO:0035255	ionotropic glutamate receptor binding	5/3863	27/18639	0.185185185185185	0.893519716972992	0.685733994485019	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	9/3863	48/18639	0.1875	0.904688713435154	0.687736482510603	1
GO:0015078	proton transmembrane transporter activity	36/3863	185/18639	0.194594594594595	0.938920178267836	0.693219013438888	1
GO:0019842	vitamin binding	29/3863	150/18639	0.193333333333333	0.932834584519803	0.69460785006415	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	25/3863	130/18639	0.192307692307692	0.927885859933491	0.69672052900392	1
GO:0031683	G-protein beta/gamma-subunit complex binding	4/3863	22/18639	0.181818181818182	0.877273903937119	0.697846932958032	1
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0004016	adenylate cyclase activity	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0008271	secondary active sulfate transmembrane transporter activity	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0010854	adenylate cyclase regulator activity	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0015173	aromatic amino acid transmembrane transporter activity	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0015217	ADP transmembrane transporter activity	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0042608	T cell receptor binding	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0048407	platelet-derived growth factor binding	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0050786	RAGE receptor binding	2/3863	11/18639	0.181818181818182	0.877273903937119	0.698891697105792	1
GO:0000146	microfilament motor activity	7/3863	38/18639	0.184210526315789	0.888816981620502	0.699163496720646	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	6/3863	33/18639	0.181818181818182	0.877273903937119	0.707266015783897	1
GO:0019838	growth factor binding	26/3863	136/18639	0.191176470588235	0.922427707816236	0.710973397033103	1
GO:0005092	GDP-dissociation inhibitor activity	3/3863	17/18639	0.176470588235294	0.85147173029191	0.715818144452077	1
GO:0008429	phosphatidylethanolamine binding	3/3863	17/18639	0.176470588235294	0.85147173029191	0.715818144452077	1
GO:0030169	low-density lipoprotein particle binding	3/3863	17/18639	0.176470588235294	0.85147173029191	0.715818144452077	1
GO:0036041	long-chain fatty acid binding	3/3863	17/18639	0.176470588235294	0.85147173029191	0.715818144452077	1
GO:0038191	neuropilin binding	3/3863	17/18639	0.176470588235294	0.85147173029191	0.715818144452077	1
GO:0045125	bioactive lipid receptor activity	3/3863	17/18639	0.176470588235294	0.85147173029191	0.715818144452077	1
GO:0070402	NADPH binding	3/3863	17/18639	0.176470588235294	0.85147173029191	0.715818144452077	1
GO:0070492	oligosaccharide binding	3/3863	17/18639	0.176470588235294	0.85147173029191	0.715818144452077	1
GO:0033218	amide binding	48/3863	247/18639	0.194331983805668	0.937653079511739	0.716770891791388	1
GO:0051959	dynein light intermediate chain binding	5/3863	28/18639	0.178571428571429	0.861608298509671	0.717879715691919	1
GO:0030971	receptor tyrosine kinase binding	15/3863	81/18639	0.185185185185185	0.893519716972992	0.729620144550079	1
GO:0000295	adenine nucleotide transmembrane transporter activity	4/3863	23/18639	0.173913043478261	0.839131560287679	0.732303723281426	1
GO:0004602	glutathione peroxidase activity	4/3863	23/18639	0.173913043478261	0.839131560287679	0.732303723281426	1
GO:0016849	phosphorus-oxygen lyase activity	4/3863	23/18639	0.173913043478261	0.839131560287679	0.732303723281426	1
GO:0090482	vitamin transmembrane transporter activity	6/3863	34/18639	0.176470588235294	0.85147173029191	0.735476530505299	1
GO:0140299	molecular sensor activity	13/3863	71/18639	0.183098591549296	0.883451889176113	0.736499130261672	1
GO:0003995	acyl-CoA dehydrogenase activity	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0004126	cytidine deaminase activity	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0004526	ribonuclease P activity	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0004859	phospholipase inhibitor activity	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0005078	MAP-kinase scaffold activity	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0005165	neurotrophin receptor binding	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0005247	voltage-gated chloride channel activity	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0005436	sodium:phosphate symporter activity	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0015132	prostaglandin transmembrane transporter activity	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0015368	calcium:monoatomic cation antiporter activity	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0016273	arginine N-methyltransferase activity	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0016274	protein-arginine N-methyltransferase activity	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0031543	peptidyl-proline dioxygenase activity	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0042301	phosphate ion binding	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0070008	serine-type exopeptidase activity	2/3863	12/18639	0.166666666666667	0.804167745275692	0.745219574820352	1
GO:0043236	laminin binding	5/3863	29/18639	0.172413793103448	0.831897667526578	0.747608735937632	1
GO:0019212	phosphatase inhibitor activity	10/3863	56/18639	0.178571428571429	0.861608298509671	0.751108461742977	1
GO:0005253	monoatomic anion channel activity	19/3863	103/18639	0.184466019417476	0.890049737489601	0.752199179419182	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	3/3863	18/18639	0.166666666666667	0.804167745275692	0.752988856442531	1
GO:0015172	acidic amino acid transmembrane transporter activity	3/3863	18/18639	0.166666666666667	0.804167745275692	0.752988856442531	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/3863	18/18639	0.166666666666667	0.804167745275692	0.752988856442531	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	3/3863	18/18639	0.166666666666667	0.804167745275692	0.752988856442531	1
GO:0030228	lipoprotein particle receptor activity	3/3863	18/18639	0.166666666666667	0.804167745275692	0.752988856442531	1
GO:1901611	phosphatidylglycerol binding	3/3863	18/18639	0.166666666666667	0.804167745275692	0.752988856442531	1
GO:0005518	collagen binding	13/3863	72/18639	0.180555555555556	0.871181724048667	0.755173657335459	1
GO:0005315	phosphate transmembrane transporter activity	4/3863	24/18639	0.166666666666667	0.804167745275692	0.763714911668978	1
GO:0005540	hyaluronic acid binding	4/3863	24/18639	0.166666666666667	0.804167745275692	0.763714911668978	1
GO:0048027	mRNA 5'-UTR binding	4/3863	24/18639	0.166666666666667	0.804167745275692	0.763714911668978	1
GO:0050699	WW domain binding	4/3863	24/18639	0.166666666666667	0.804167745275692	0.763714911668978	1
GO:0003779	actin binding	86/3863	443/18639	0.194130925507901	0.936682971923831	0.771587015806311	1
GO:0017080	sodium channel regulator activity	7/3863	41/18639	0.170731707317073	0.823781592721441	0.774660525796328	1
GO:0016769	transferase activity, transferring nitrogenous groups	5/3863	30/18639	0.166666666666667	0.804167745275692	0.774945248980679	1
GO:0048019	receptor antagonist activity	5/3863	30/18639	0.166666666666667	0.804167745275692	0.774945248980679	1
GO:0005507	copper ion binding	11/3863	63/18639	0.174603174603175	0.842461447431678	0.783691303128768	1
GO:1901682	sulfur compound transmembrane transporter activity	11/3863	63/18639	0.174603174603175	0.842461447431678	0.783691303128768	1
GO:0033293	monocarboxylic acid binding	14/3863	79/18639	0.177215189873418	0.85506443801466	0.785006338966203	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/3863	13/18639	0.153846153846154	0.742308687946793	0.785283261980234	1
GO:0008035	high-density lipoprotein particle binding	2/3863	13/18639	0.153846153846154	0.742308687946793	0.785283261980234	1
GO:0008417	fucosyltransferase activity	2/3863	13/18639	0.153846153846154	0.742308687946793	0.785283261980234	1
GO:0019104	DNA N-glycosylase activity	2/3863	13/18639	0.153846153846154	0.742308687946793	0.785283261980234	1
GO:0030955	potassium ion binding	2/3863	13/18639	0.153846153846154	0.742308687946793	0.785283261980234	1
GO:0043560	insulin receptor substrate binding	2/3863	13/18639	0.153846153846154	0.742308687946793	0.785283261980234	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/3863	13/18639	0.153846153846154	0.742308687946793	0.785283261980234	1
GO:0071714	icosanoid transmembrane transporter activity	2/3863	13/18639	0.153846153846154	0.742308687946793	0.785283261980234	1
GO:0004190	aspartic-type endopeptidase activity	6/3863	36/18639	0.166666666666667	0.804167745275692	0.785940246196735	1
GO:0005520	insulin-like growth factor binding	3/3863	19/18639	0.157894736842105	0.761843127103288	0.786137532112606	1
GO:0015245	fatty acid transmembrane transporter activity	3/3863	19/18639	0.157894736842105	0.761843127103288	0.786137532112606	1
GO:0022821	solute:potassium antiporter activity	3/3863	19/18639	0.157894736842105	0.761843127103288	0.786137532112606	1
GO:0030506	ankyrin binding	3/3863	19/18639	0.157894736842105	0.761843127103288	0.786137532112606	1
GO:0008483	transaminase activity	4/3863	25/18639	0.16	0.772001035464665	0.792171440326925	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	4/3863	25/18639	0.16	0.772001035464665	0.792171440326925	1
GO:0031492	nucleosomal DNA binding	7/3863	42/18639	0.166666666666667	0.804167745275692	0.796452195856024	1
GO:0004864	protein phosphatase inhibitor activity	9/3863	53/18639	0.169811320754717	0.819340721601649	0.797708628182623	1
GO:0005164	tumor necrosis factor receptor binding	5/3863	31/18639	0.161290322580645	0.778226850266799	0.799948095239808	1
GO:0008237	metallopeptidase activity	34/3863	184/18639	0.184782608695652	0.891577282805659	0.800168181054121	1
GO:0048306	calcium-dependent protein binding	14/3863	80/18639	0.175	0.844376132539477	0.800700102748344	1
GO:0023023	MHC protein complex binding	6/3863	37/18639	0.162162162162162	0.782433481889863	0.808259083864697	1
GO:0030551	cyclic nucleotide binding	6/3863	37/18639	0.162162162162162	0.782433481889863	0.808259083864697	1
GO:0043394	proteoglycan binding	6/3863	37/18639	0.162162162162162	0.782433481889863	0.808259083864697	1
GO:0070001	aspartic-type peptidase activity	6/3863	37/18639	0.162162162162162	0.782433481889863	0.808259083864697	1
GO:0038024	cargo receptor activity	11/3863	65/18639	0.169230769230769	0.816539556741472	0.817587113498222	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/3863	26/18639	0.153846153846154	0.742308687946793	0.817804399899632	1
GO:0030507	spectrin binding	4/3863	26/18639	0.153846153846154	0.742308687946793	0.817804399899632	1
GO:0005313	L-glutamate transmembrane transporter activity	2/3863	14/18639	0.142857142857143	0.689286638807736	0.819688682861008	1
GO:0005347	ATP transmembrane transporter activity	2/3863	14/18639	0.142857142857143	0.689286638807736	0.819688682861008	1
GO:0008191	metalloendopeptidase inhibitor activity	2/3863	14/18639	0.142857142857143	0.689286638807736	0.819688682861008	1
GO:0031404	chloride ion binding	2/3863	14/18639	0.142857142857143	0.689286638807736	0.819688682861008	1
GO:0044548	S100 protein binding	2/3863	14/18639	0.142857142857143	0.689286638807736	0.819688682861008	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/3863	14/18639	0.142857142857143	0.689286638807736	0.819688682861008	1
GO:1901612	cardiolipin binding	2/3863	14/18639	0.142857142857143	0.689286638807736	0.819688682861008	1
GO:0008378	galactosyltransferase activity	5/3863	32/18639	0.15625	0.753907261195962	0.82270324525889	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/3863	32/18639	0.15625	0.753907261195962	0.82270324525889	1
GO:0071813	lipoprotein particle binding	5/3863	32/18639	0.15625	0.753907261195962	0.82270324525889	1
GO:0071814	protein-lipid complex binding	5/3863	32/18639	0.15625	0.753907261195962	0.82270324525889	1
GO:0042887	amide transmembrane transporter activity	6/3863	38/18639	0.157894736842105	0.761843127103288	0.828714506454207	1
GO:0015297	antiporter activity	24/3863	135/18639	0.177777777777778	0.857778928294072	0.829736710481837	1
GO:0015026	coreceptor activity	10/3863	61/18639	0.163934426229508	0.790984667484288	0.840152881730641	1
GO:0005044	scavenger receptor activity	4/3863	27/18639	0.148148148148148	0.714815773578393	0.840773166058695	1
GO:0051428	peptide hormone receptor binding	3/3863	21/18639	0.142857142857143	0.689286638807736	0.841372124238789	1
GO:0001540	amyloid-beta binding	14/3863	83/18639	0.168674698795181	0.813856513291062	0.842783291116068	1
GO:0042562	hormone binding	16/3863	94/18639	0.170212765957447	0.821277697302835	0.845543057722894	1
GO:0170055	lipid transmembrane transporter activity	9/3863	56/18639	0.160714285714286	0.775447468658704	0.848233193262609	1
GO:0004129	cytochrome-c oxidase activity	2/3863	15/18639	0.133333333333333	0.643334196220554	0.849059722094348	1
GO:0005523	tropomyosin binding	2/3863	15/18639	0.133333333333333	0.643334196220554	0.849059722094348	1
GO:0010181	FMN binding	2/3863	15/18639	0.133333333333333	0.643334196220554	0.849059722094348	1
GO:0015116	sulfate transmembrane transporter activity	2/3863	15/18639	0.133333333333333	0.643334196220554	0.849059722094348	1
GO:0033130	acetylcholine receptor binding	2/3863	15/18639	0.133333333333333	0.643334196220554	0.849059722094348	1
GO:0048531	beta-1,3-galactosyltransferase activity	2/3863	15/18639	0.133333333333333	0.643334196220554	0.849059722094348	1
GO:0050780	dopamine receptor binding	2/3863	15/18639	0.133333333333333	0.643334196220554	0.849059722094348	1
GO:0051371	muscle alpha-actinin binding	2/3863	15/18639	0.133333333333333	0.643334196220554	0.849059722094348	1
GO:0061134	peptidase regulator activity	41/3863	226/18639	0.18141592920354	0.875333032468232	0.852836468797557	1
GO:0004521	RNA endonuclease activity	12/3863	73/18639	0.164383561643836	0.793151748765067	0.85416656654107	1
GO:0022804	active transmembrane transporter activity	86/3863	457/18639	0.188183807439825	0.907988088757675	0.859644969645077	1
GO:0016866	intramolecular transferase activity	4/3863	28/18639	0.142857142857143	0.689286638807736	0.861255407786491	1
GO:0051393	alpha-actinin binding	4/3863	28/18639	0.142857142857143	0.689286638807736	0.861255407786491	1
GO:0008376	acetylgalactosaminyltransferase activity	5/3863	34/18639	0.147058823529412	0.709559775243258	0.86191022687989	1
GO:0004601	peroxidase activity	9/3863	57/18639	0.157894736842105	0.761843127103288	0.862667254338788	1
GO:0005243	gap junction channel activity	3/3863	22/18639	0.136363636363636	0.657955427952839	0.864033996546277	1
GO:0019955	cytokine binding	25/3863	144/18639	0.173611111111111	0.83767473466218	0.866152897189929	1
GO:0048029	monosaccharide binding	12/3863	74/18639	0.162162162162162	0.782433481889863	0.866627459727033	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/3863	16/18639	0.125	0.603125808956769	0.874004761456105	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/3863	16/18639	0.125	0.603125808956769	0.874004761456105	1
GO:0055102	lipase inhibitor activity	2/3863	16/18639	0.125	0.603125808956769	0.874004761456105	1
GO:0016229	steroid dehydrogenase activity	5/3863	35/18639	0.142857142857143	0.689286638807736	0.878612884950625	1
GO:0004629	phospholipase C activity	4/3863	29/18639	0.137931034482759	0.665518134021263	0.879438875282309	1
GO:0035250	UDP-galactosyltransferase activity	4/3863	29/18639	0.137931034482759	0.665518134021263	0.879438875282309	1
GO:0099604	ligand-gated calcium channel activity	4/3863	29/18639	0.137931034482759	0.665518134021263	0.879438875282309	1
GO:0140828	metal cation:monoatomic cation antiporter activity	6/3863	41/18639	0.146341463414634	0.706098508046949	0.879737393768904	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	22/3863	130/18639	0.169230769230769	0.816539556741472	0.883336362532812	1
GO:0005212	structural constituent of eye lens	3/3863	23/18639	0.130434782608696	0.629348670215759	0.883793537536004	1
GO:0031681	G-protein beta-subunit binding	3/3863	23/18639	0.130434782608696	0.629348670215759	0.883793537536004	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/3863	23/18639	0.130434782608696	0.629348670215759	0.883793537536004	1
GO:0016782	transferase activity, transferring sulphur-containing groups	11/3863	70/18639	0.157142857142857	0.75821530268851	0.884683278202414	1
GO:0005246	calcium channel regulator activity	8/3863	53/18639	0.150943396226415	0.72830286364591	0.884907705657347	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	9/3863	59/18639	0.152542372881356	0.736017936354024	0.88821093631952	1
GO:0004033	aldo-keto reductase (NADPH) activity	5/3863	36/18639	0.138888888888889	0.670139787729744	0.893560084749639	1
GO:0045505	dynein intermediate chain binding	5/3863	36/18639	0.138888888888889	0.670139787729744	0.893560084749639	1
GO:0055106	ubiquitin-protein transferase regulator activity	5/3863	36/18639	0.138888888888889	0.670139787729744	0.893560084749639	1
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/3863	17/18639	0.117647058823529	0.567647820194606	0.895096310389975	1
GO:0008484	sulfuric ester hydrolase activity	2/3863	17/18639	0.117647058823529	0.567647820194606	0.895096310389975	1
GO:0009881	photoreceptor activity	2/3863	17/18639	0.117647058823529	0.567647820194606	0.895096310389975	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/3863	17/18639	0.117647058823529	0.567647820194606	0.895096310389975	1
GO:0016018	cyclosporin A binding	2/3863	17/18639	0.117647058823529	0.567647820194606	0.895096310389975	1
GO:0045236	CXCR chemokine receptor binding	2/3863	17/18639	0.117647058823529	0.567647820194606	0.895096310389975	1
GO:0001965	G-protein alpha-subunit binding	4/3863	30/18639	0.133333333333333	0.643334196220554	0.895514817790252	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	4/3863	30/18639	0.133333333333333	0.643334196220554	0.895514817790252	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	4/3863	30/18639	0.133333333333333	0.643334196220554	0.895514817790252	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/3863	24/18639	0.125	0.603125808956769	0.90094762694558	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	3/3863	24/18639	0.125	0.603125808956769	0.90094762694558	1
GO:0015295	solute:proton symporter activity	3/3863	24/18639	0.125	0.603125808956769	0.90094762694558	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/3863	24/18639	0.125	0.603125808956769	0.90094762694558	1
GO:0030215	semaphorin receptor binding	3/3863	24/18639	0.125	0.603125808956769	0.90094762694558	1
GO:0070300	phosphatidic acid binding	3/3863	24/18639	0.125	0.603125808956769	0.90094762694558	1
GO:0000182	rDNA binding	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0003796	lysozyme activity	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0004090	carbonyl reductase (NADPH) activity	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0005522	profilin binding	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0019531	oxalate transmembrane transporter activity	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0035256	G protein-coupled glutamate receptor binding	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0035374	chondroitin sulfate binding	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0051880	G-quadruplex DNA binding	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0070097	delta-catenin binding	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0140940	histone H2A methyltransferase activity	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0140999	histone H3K4 trimethyltransferase activity	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0141109	transporter activator activity	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:1990259	histone H2AQ104 methyltransferase activity	1/3863	10/18639	0.1	0.482500647165416	0.90203554769353	1
GO:0005506	iron ion binding	26/3863	154/18639	0.168831168831169	0.814611482227325	0.902404981733889	1
GO:0004175	endopeptidase activity	74/3863	405/18639	0.182716049382716	0.881606120746685	0.903584933926961	1
GO:0008509	monoatomic anion transmembrane transporter activity	25/3863	149/18639	0.167785234899329	0.809564844237274	0.904942502736348	1
GO:0004857	enzyme inhibitor activity	76/3863	416/18639	0.182692307692308	0.881491566936817	0.906594916760906	1
GO:0031406	carboxylic acid binding	32/3863	187/18639	0.171122994652406	0.8256695566467	0.908294020790005	1
GO:0005452	solute:inorganic anion antiporter activity	4/3863	31/18639	0.129032258064516	0.622581480213439	0.909672850760688	1
GO:0047499	calcium-independent phospholipase A2 activity	4/3863	31/18639	0.129032258064516	0.622581480213439	0.909672850760688	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	10/3863	67/18639	0.149253731343284	0.720150219649874	0.911848541851037	1
GO:0005178	integrin binding	27/3863	161/18639	0.167701863354037	0.809162575991691	0.912848437920372	1
GO:0016854	racemase and epimerase activity	2/3863	18/18639	0.111111111111111	0.536111830183795	0.912859742133406	1
GO:0034185	apolipoprotein binding	2/3863	18/18639	0.111111111111111	0.536111830183795	0.912859742133406	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/3863	18/18639	0.111111111111111	0.536111830183795	0.912859742133406	1
GO:0005537	D-mannose binding	3/3863	25/18639	0.12	0.579000776598499	0.915780743302669	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/3863	25/18639	0.12	0.579000776598499	0.915780743302669	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/3863	25/18639	0.12	0.579000776598499	0.915780743302669	1
GO:0030547	signaling receptor inhibitor activity	6/3863	44/18639	0.136363636363636	0.657955427952839	0.917307881243967	1
GO:0043177	organic acid binding	32/3863	189/18639	0.169312169312169	0.816932312661021	0.919497078631389	1
GO:0042910	xenobiotic transmembrane transporter activity	4/3863	32/18639	0.125	0.603125808956769	0.922097080118088	1
GO:0047498	calcium-dependent phospholipase A2 activity	4/3863	32/18639	0.125	0.603125808956769	0.922097080118088	1
GO:0001851	complement component C3b binding	1/3863	11/18639	0.0909090909090909	0.43863695196856	0.922349932752303	1
GO:0005114	type II transforming growth factor beta receptor binding	1/3863	11/18639	0.0909090909090909	0.43863695196856	0.922349932752303	1
GO:0005536	D-glucose binding	1/3863	11/18639	0.0909090909090909	0.43863695196856	0.922349932752303	1
GO:0008046	axon guidance receptor activity	1/3863	11/18639	0.0909090909090909	0.43863695196856	0.922349932752303	1
GO:0008172	S-methyltransferase activity	1/3863	11/18639	0.0909090909090909	0.43863695196856	0.922349932752303	1
GO:0008199	ferric iron binding	1/3863	11/18639	0.0909090909090909	0.43863695196856	0.922349932752303	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/3863	11/18639	0.0909090909090909	0.43863695196856	0.922349932752303	1
GO:0032794	GTPase activating protein binding	1/3863	11/18639	0.0909090909090909	0.43863695196856	0.922349932752303	1
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/3863	11/18639	0.0909090909090909	0.43863695196856	0.922349932752303	1
GO:0097493	structural molecule activity conferring elasticity	1/3863	11/18639	0.0909090909090909	0.43863695196856	0.922349932752303	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/3863	11/18639	0.0909090909090909	0.43863695196856	0.922349932752303	1
GO:0005010	insulin-like growth factor receptor activity	7/3863	51/18639	0.137254901960784	0.662255790227041	0.926650018892755	1
GO:0005030	neurotrophin receptor activity	7/3863	51/18639	0.137254901960784	0.662255790227041	0.926650018892755	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/3863	19/18639	0.105263157894737	0.507895418068858	0.92776823742997	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	2/3863	19/18639	0.105263157894737	0.507895418068858	0.92776823742997	1
GO:0034987	immunoglobulin receptor binding	2/3863	19/18639	0.105263157894737	0.507895418068858	0.92776823742997	1
GO:0042577	lipid phosphatase activity	2/3863	19/18639	0.105263157894737	0.507895418068858	0.92776823742997	1
GO:0042834	peptidoglycan binding	2/3863	19/18639	0.105263157894737	0.507895418068858	0.92776823742997	1
GO:0004435	phosphatidylinositol phospholipase C activity	3/3863	26/18639	0.115384615384615	0.556731515960095	0.928560266355239	1
GO:0005227	calcium-activated cation channel activity	3/3863	26/18639	0.115384615384615	0.556731515960095	0.928560266355239	1
GO:0043548	phosphatidylinositol 3-kinase binding	3/3863	26/18639	0.115384615384615	0.556731515960095	0.928560266355239	1
GO:0019956	chemokine binding	4/3863	33/18639	0.121212121212121	0.584849269291413	0.932963293067263	1
GO:0004536	DNA nuclease activity	9/3863	64/18639	0.140625	0.678516535076366	0.93529393825211	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	10/3863	70/18639	0.142857142857143	0.689286638807736	0.936055467221044	1
GO:0000340	RNA 7-methylguanosine cap binding	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:0004032	aldose reductase (NADPH) activity	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:0008179	adenylate cyclase binding	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:0008504	monoamine transmembrane transporter activity	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:0008603	cAMP-dependent protein kinase regulator activity	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:0010853	cyclase activator activity	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:0015269	calcium-activated potassium channel activity	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:0016208	AMP binding	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:0016840	carbon-nitrogen lyase activity	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:0036009	protein-glutamine N-methyltransferase activity	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:0140900	chloride:bicarbonate antiporter activity	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/3863	12/18639	0.0833333333333333	0.402083872637846	0.938452692564299	1
GO:0005104	fibroblast growth factor receptor binding	3/3863	27/18639	0.111111111111111	0.536111830183795	0.939533653892307	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	3/3863	27/18639	0.111111111111111	0.536111830183795	0.939533653892307	1
GO:0001972	retinoic acid binding	2/3863	20/18639	0.1	0.482500647165416	0.940241847525322	1
GO:0010851	cyclase regulator activity	2/3863	20/18639	0.1	0.482500647165416	0.940241847525322	1
GO:0001786	phosphatidylserine binding	8/3863	59/18639	0.135593220338983	0.654238165648021	0.942281895790318	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	4/3863	34/18639	0.117647058823529	0.567647820194606	0.942437035225579	1
GO:0051427	hormone receptor binding	4/3863	34/18639	0.117647058823529	0.567647820194606	0.942437035225579	1
GO:0008146	sulfotransferase activity	7/3863	53/18639	0.132075471698113	0.637265005690171	0.942842470688926	1
GO:0038064	collagen receptor activity	7/3863	53/18639	0.132075471698113	0.637265005690171	0.942842470688926	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	5/3863	41/18639	0.121951219512195	0.588415423372458	0.946651948407912	1
GO:0042287	MHC protein binding	5/3863	41/18639	0.121951219512195	0.588415423372458	0.946651948407912	1
GO:0045499	chemorepellent activity	3/3863	28/18639	0.107142857142857	0.516964979105802	0.948927043425005	1
GO:0015125	bile acid transmembrane transporter activity	2/3863	21/18639	0.0952380952380952	0.459524425871824	0.950649186818641	1
GO:0015174	basic amino acid transmembrane transporter activity	2/3863	21/18639	0.0952380952380952	0.459524425871824	0.950649186818641	1
GO:0019200	carbohydrate kinase activity	2/3863	21/18639	0.0952380952380952	0.459524425871824	0.950649186818641	1
GO:0061891	calcium ion sensor activity	2/3863	21/18639	0.0952380952380952	0.459524425871824	0.950649186818641	1
GO:0004623	phospholipase A2 activity	4/3863	35/18639	0.114285714285714	0.551429311046189	0.950672409454606	1
GO:0002161	aminoacyl-tRNA editing activity	1/3863	13/18639	0.0769230769230769	0.371154343973397	0.951216811779637	1
GO:0005542	folic acid binding	1/3863	13/18639	0.0769230769230769	0.371154343973397	0.951216811779637	1
GO:0009982	pseudouridine synthase activity	1/3863	13/18639	0.0769230769230769	0.371154343973397	0.951216811779637	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/3863	13/18639	0.0769230769230769	0.371154343973397	0.951216811779637	1
GO:0031432	titin binding	1/3863	13/18639	0.0769230769230769	0.371154343973397	0.951216811779637	1
GO:0031994	insulin-like growth factor I binding	1/3863	13/18639	0.0769230769230769	0.371154343973397	0.951216811779637	1
GO:0061459	L-arginine transmembrane transporter activity	1/3863	13/18639	0.0769230769230769	0.371154343973397	0.951216811779637	1
GO:0070700	BMP receptor binding	1/3863	13/18639	0.0769230769230769	0.371154343973397	0.951216811779637	1
GO:0071837	HMG box domain binding	1/3863	13/18639	0.0769230769230769	0.371154343973397	0.951216811779637	1
GO:1901338	catecholamine binding	1/3863	13/18639	0.0769230769230769	0.371154343973397	0.951216811779637	1
GO:0038187	pattern recognition receptor activity	6/3863	48/18639	0.125	0.603125808956769	0.951237863555346	1
GO:0003774	cytoskeletal motor activity	24/3863	153/18639	0.156862745098039	0.756863760259475	0.953790812325806	1
GO:0004520	DNA endonuclease activity	5/3863	42/18639	0.119047619047619	0.57440553233978	0.953818663045776	1
GO:0042056	chemoattractant activity	5/3863	42/18639	0.119047619047619	0.57440553233978	0.953818663045776	1
GO:0003785	actin monomer binding	3/3863	29/18639	0.103448275862069	0.499138600515947	0.956944908979931	1
GO:0005004	GPI-linked ephrin receptor activity	6/3863	49/18639	0.122448979591837	0.59081711897806	0.95746859024076	1
GO:0005008	hepatocyte growth factor receptor activity	6/3863	49/18639	0.122448979591837	0.59081711897806	0.95746859024076	1
GO:0005009	insulin receptor activity	6/3863	49/18639	0.122448979591837	0.59081711897806	0.95746859024076	1
GO:0005011	macrophage colony-stimulating factor receptor activity	6/3863	49/18639	0.122448979591837	0.59081711897806	0.95746859024076	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	6/3863	49/18639	0.122448979591837	0.59081711897806	0.95746859024076	1
GO:0005020	stem cell factor receptor activity	6/3863	49/18639	0.122448979591837	0.59081711897806	0.95746859024076	1
GO:0008288	boss receptor activity	6/3863	49/18639	0.122448979591837	0.59081711897806	0.95746859024076	1
GO:0036332	placental growth factor receptor activity	6/3863	49/18639	0.122448979591837	0.59081711897806	0.95746859024076	1
GO:0038062	protein tyrosine kinase collagen receptor activity	6/3863	49/18639	0.122448979591837	0.59081711897806	0.95746859024076	1
GO:0060175	brain-derived neurotrophic factor receptor activity	6/3863	49/18639	0.122448979591837	0.59081711897806	0.95746859024076	1
GO:0015377	chloride:monoatomic cation symporter activity	2/3863	22/18639	0.0909090909090909	0.43863695196856	0.959310705845878	1
GO:0140784	metal ion sensor activity	2/3863	22/18639	0.0909090909090909	0.43863695196856	0.959310705845878	1
GO:0052689	carboxylic ester hydrolase activity	13/3863	92/18639	0.141304347826087	0.681794392733739	0.960057328847931	1
GO:0015179	L-amino acid transmembrane transporter activity	8/3863	62/18639	0.129032258064516	0.622581480213439	0.960084418900711	1
GO:0004065	arylsulfatase activity	1/3863	14/18639	0.0714285714285714	0.344643319403868	0.961334360157994	1
GO:0008195	phosphatidate phosphatase activity	1/3863	14/18639	0.0714285714285714	0.344643319403868	0.961334360157994	1
GO:0008494	translation activator activity	1/3863	14/18639	0.0714285714285714	0.344643319403868	0.961334360157994	1
GO:0019763	immunoglobulin receptor activity	1/3863	14/18639	0.0714285714285714	0.344643319403868	0.961334360157994	1
GO:0019992	diacylglycerol binding	1/3863	14/18639	0.0714285714285714	0.344643319403868	0.961334360157994	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/3863	14/18639	0.0714285714285714	0.344643319403868	0.961334360157994	1
GO:0043176	amine binding	1/3863	14/18639	0.0714285714285714	0.344643319403868	0.961334360157994	1
GO:0061783	peptidoglycan muralytic activity	1/3863	14/18639	0.0714285714285714	0.344643319403868	0.961334360157994	1
GO:1901474	azole transmembrane transporter activity	1/3863	14/18639	0.0714285714285714	0.344643319403868	0.961334360157994	1
GO:0004519	endonuclease activity	19/3863	127/18639	0.149606299212598	0.721851361901015	0.961450584904274	1
GO:0005006	epidermal growth factor receptor activity	6/3863	50/18639	0.12	0.579000776598499	0.962967719191508	1
GO:0005007	fibroblast growth factor receptor activity	6/3863	50/18639	0.12	0.579000776598499	0.962967719191508	1
GO:0005017	platelet-derived growth factor receptor activity	6/3863	50/18639	0.12	0.579000776598499	0.962967719191508	1
GO:0005019	platelet-derived growth factor beta-receptor activity	6/3863	50/18639	0.12	0.579000776598499	0.962967719191508	1
GO:0001968	fibronectin binding	3/3863	30/18639	0.1	0.482500647165416	0.963770474667673	1
GO:0022839	monoatomic ion-gated channel activity	3/3863	30/18639	0.1	0.482500647165416	0.963770474667673	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/3863	23/18639	0.0869565217391304	0.419565780143839	0.966502817113485	1
GO:0043274	phospholipase binding	2/3863	23/18639	0.0869565217391304	0.419565780143839	0.966502817113485	1
GO:0005021	vascular endothelial growth factor receptor activity	6/3863	51/18639	0.117647058823529	0.567647820194606	0.967810079231342	1
GO:0016597	amino acid binding	6/3863	51/18639	0.117647058823529	0.567647820194606	0.967810079231342	1
GO:0005200	structural constituent of cytoskeleton	16/3863	112/18639	0.142857142857143	0.689286638807736	0.968961718120636	1
GO:0004089	carbonate dehydratase activity	1/3863	15/18639	0.0666666666666667	0.321667098110277	0.96935397716254	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/3863	15/18639	0.0666666666666667	0.321667098110277	0.96935397716254	1
GO:0008242	omega peptidase activity	1/3863	15/18639	0.0666666666666667	0.321667098110277	0.96935397716254	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/3863	15/18639	0.0666666666666667	0.321667098110277	0.96935397716254	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/3863	15/18639	0.0666666666666667	0.321667098110277	0.96935397716254	1
GO:0030553	cGMP binding	1/3863	15/18639	0.0666666666666667	0.321667098110277	0.96935397716254	1
GO:0034483	heparan sulfate sulfotransferase activity	1/3863	15/18639	0.0666666666666667	0.321667098110277	0.96935397716254	1
GO:0045504	dynein heavy chain binding	1/3863	15/18639	0.0666666666666667	0.321667098110277	0.96935397716254	1
GO:0047372	monoacylglycerol lipase activity	1/3863	15/18639	0.0666666666666667	0.321667098110277	0.96935397716254	1
GO:0140161	monocarboxylate:sodium symporter activity	1/3863	15/18639	0.0666666666666667	0.321667098110277	0.96935397716254	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	28/3863	181/18639	0.154696132596685	0.746409840918875	0.970949702452675	1
GO:0005254	chloride channel activity	11/3863	83/18639	0.132530120481928	0.639458689014406	0.971052692646221	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	6/3863	52/18639	0.115384615384615	0.556731515960095	0.972064779661126	1
GO:0019957	C-C chemokine binding	2/3863	24/18639	0.0833333333333333	0.402083872637846	0.972462379856021	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/3863	39/18639	0.102564102564103	0.494872458631195	0.973888441977138	1
GO:0019199	transmembrane receptor protein kinase activity	10/3863	78/18639	0.128205128205128	0.618590573288994	0.974604040417416	1
GO:0019841	retinol binding	1/3863	16/18639	0.0625	0.301562904478385	0.975710591542969	1
GO:0022841	potassium ion leak channel activity	1/3863	16/18639	0.0625	0.301562904478385	0.975710591542969	1
GO:0005003	ephrin receptor activity	6/3863	53/18639	0.113207547169811	0.546227147734433	0.975795287189492	1
GO:0005005	transmembrane-ephrin receptor activity	6/3863	53/18639	0.113207547169811	0.546227147734433	0.975795287189492	1
GO:0017046	peptide hormone binding	6/3863	53/18639	0.113207547169811	0.546227147734433	0.975795287189492	1
GO:0072341	modified amino acid binding	12/3863	91/18639	0.131868131868132	0.63626458966868	0.976845058149087	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	7/3863	60/18639	0.116666666666667	0.562917421692985	0.977373212701364	1
GO:0015271	outward rectifier potassium channel activity	2/3863	25/18639	0.08	0.386000517732332	0.977391217817183	1
GO:0099095	ligand-gated monoatomic anion channel activity	5/3863	47/18639	0.106382978723404	0.513298560814272	0.978135024820719	1
GO:0030296	protein tyrosine kinase activator activity	3/3863	33/18639	0.0909090909090909	0.43863695196856	0.978628693740225	1
GO:0042923	neuropeptide binding	3/3863	33/18639	0.0909090909090909	0.43863695196856	0.978628693740225	1
GO:0016500	protein-hormone receptor activity	8/3863	67/18639	0.119402985074627	0.576120175719899	0.979071134726511	1
GO:0016247	channel regulator activity	25/3863	168/18639	0.148809523809524	0.718006915424725	0.979136971387139	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/3863	17/18639	0.0588235294117647	0.283823910097303	0.980748984115031	1
GO:0030548	acetylcholine receptor regulator activity	1/3863	17/18639	0.0588235294117647	0.283823910097303	0.980748984115031	1
GO:1901681	sulfur compound binding	44/3863	275/18639	0.16	0.772001035464665	0.98091241325008	1
GO:0046906	tetrapyrrole binding	22/3863	152/18639	0.144736842105263	0.69835619984468	0.981270552388923	1
GO:0003735	structural constituent of ribosome	26/3863	175/18639	0.148571428571429	0.716858104360046	0.981406320128459	1
GO:0019865	immunoglobulin binding	2/3863	26/18639	0.0769230769230769	0.371154343973397	0.981460463772345	1
GO:0015020	glucuronosyltransferase activity	3/3863	34/18639	0.0882352941176471	0.425735865145955	0.982131112306159	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	3/3863	34/18639	0.0882352941176471	0.425735865145955	0.982131112306159	1
GO:0015291	secondary active transmembrane transporter activity	46/3863	287/18639	0.160278745644599	0.773345985003802	0.982270377711873	1
GO:0141108	transporter regulator activity	25/3863	170/18639	0.147058823529412	0.709559775243258	0.982538986451424	1
GO:0008307	structural constituent of muscle	4/3863	42/18639	0.0952380952380952	0.459524425871824	0.984072401374455	1
GO:0099602	neurotransmitter receptor regulator activity	1/3863	18/18639	0.0555555555555556	0.268055915091897	0.984742468937479	1
GO:0099106	ion channel regulator activity	23/3863	160/18639	0.14375	0.693594680300285	0.984794600439204	1
GO:0015252	proton channel activity	2/3863	27/18639	0.0740740740740741	0.357407886789197	0.984814608562748	1
GO:0004896	cytokine receptor activity	12/3863	96/18639	0.125	0.603125808956769	0.987131206908942	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/3863	36/18639	0.0833333333333333	0.402083872637846	0.987559358030834	1
GO:0005242	inward rectifier potassium channel activity	2/3863	28/18639	0.0714285714285714	0.344643319403868	0.98757519049642	1
GO:0050698	proteoglycan sulfotransferase activity	2/3863	28/18639	0.0714285714285714	0.344643319403868	0.98757519049642	1
GO:0051119	sugar transmembrane transporter activity	2/3863	28/18639	0.0714285714285714	0.344643319403868	0.98757519049642	1
GO:0008381	mechanosensitive monoatomic ion channel activity	1/3863	19/18639	0.0526315789473684	0.253947709034429	0.98790770402123	1
GO:0008574	plus-end-directed microtubule motor activity	1/3863	19/18639	0.0526315789473684	0.253947709034429	0.98790770402123	1
GO:0016918	retinal binding	1/3863	19/18639	0.0526315789473684	0.253947709034429	0.98790770402123	1
GO:0022840	leak channel activity	1/3863	19/18639	0.0526315789473684	0.253947709034429	0.98790770402123	1
GO:0022842	narrow pore channel activity	1/3863	19/18639	0.0526315789473684	0.253947709034429	0.98790770402123	1
GO:0004620	phospholipase activity	14/3863	109/18639	0.128440366972477	0.619725601863836	0.988117266555169	1
GO:0015459	potassium channel regulator activity	6/3863	59/18639	0.101694915254237	0.490678624236016	0.990064858417629	1
GO:0015085	calcium ion transmembrane transporter activity	20/3863	147/18639	0.136054421768707	0.656463465531178	0.990307224591895	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/3863	20/18639	0.05	0.241250323582708	0.990416433310488	1
GO:0030627	pre-mRNA 5'-splice site binding	1/3863	20/18639	0.05	0.241250323582708	0.990416433310488	1
GO:0005501	retinoid binding	3/3863	38/18639	0.0789473684210526	0.380921563551644	0.991382279496909	1
GO:0019840	isoprenoid binding	3/3863	38/18639	0.0789473684210526	0.380921563551644	0.991382279496909	1
GO:0008514	organic anion transmembrane transporter activity	41/3863	269/18639	0.152416356877323	0.735409908319035	0.991431641824288	1
GO:0005126	cytokine receptor binding	42/3863	275/18639	0.152727272727273	0.73691007930718	0.991695457648163	1
GO:0061135	endopeptidase regulator activity	26/3863	184/18639	0.141304347826087	0.681794392733739	0.991833677862966	1
GO:0008081	phosphoric diester hydrolase activity	10/3863	87/18639	0.114942528735632	0.554598445017719	0.991879489085879	1
GO:0005248	voltage-gated sodium channel activity	1/3863	21/18639	0.0476190476190476	0.229762212935912	0.99240479563508	1
GO:0036122	BMP binding	1/3863	21/18639	0.0476190476190476	0.229762212935912	0.99240479563508	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/3863	31/18639	0.0645161290322581	0.31129074010672	0.993233388506734	1
GO:0004867	serine-type endopeptidase inhibitor activity	11/3863	95/18639	0.115789473684211	0.558684959875744	0.993377306537308	1
GO:0015108	chloride transmembrane transporter activity	15/3863	121/18639	0.12396694214876	0.598141298138945	0.993974327770634	1
GO:0016881	acid-amino acid ligase activity	1/3863	22/18639	0.0454545454545455	0.21931847598428	0.993980704672661	1
GO:0033038	bitter taste receptor activity	1/3863	22/18639	0.0454545454545455	0.21931847598428	0.993980704672661	1
GO:0015144	carbohydrate transmembrane transporter activity	3/3863	40/18639	0.075	0.361875485374062	0.994057830017315	1
GO:0030246	carbohydrate binding	42/3863	280/18639	0.15	0.723750970748123	0.994442086498246	1
GO:0015103	inorganic anion transmembrane transporter activity	22/3863	165/18639	0.133333333333333	0.643334196220554	0.99483511984926	1
GO:0004222	metalloendopeptidase activity	13/3863	110/18639	0.118181818181818	0.570228037559127	0.99501065458625	1
GO:0004812	aminoacyl-tRNA ligase activity	3/3863	41/18639	0.0731707317073171	0.353049254023475	0.995073625047982	1
GO:0008227	G protein-coupled amine receptor activity	3/3863	41/18639	0.0731707317073171	0.353049254023475	0.995073625047982	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	3/3863	41/18639	0.0731707317073171	0.353049254023475	0.995073625047982	1
GO:0005283	amino acid:sodium symporter activity	1/3863	23/18639	0.0434782608695652	0.20978289007192	0.995229699561715	1
GO:0016493	C-C chemokine receptor activity	1/3863	23/18639	0.0434782608695652	0.20978289007192	0.995229699561715	1
GO:0020037	heme binding	18/3863	142/18639	0.126760563380282	0.611620538660386	0.995477880764911	1
GO:0015149	hexose transmembrane transporter activity	1/3863	24/18639	0.0416666666666667	0.201041936318923	0.99621958302718	1
GO:0055056	D-glucose transmembrane transporter activity	1/3863	24/18639	0.0416666666666667	0.201041936318923	0.99621958302718	1
GO:0005245	voltage-gated calcium channel activity	3/3863	43/18639	0.0697674418604651	0.336628358487499	0.99662400348618	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3/3863	43/18639	0.0697674418604651	0.336628358487499	0.99662400348618	1
GO:0005251	delayed rectifier potassium channel activity	1/3863	25/18639	0.04	0.193000258866166	0.997004098244263	1
GO:0005343	organic acid:sodium symporter activity	2/3863	35/18639	0.0571428571428571	0.275714655523095	0.997025243541252	1
GO:0015293	symporter activity	18/3863	146/18639	0.123287671232877	0.5948638115738	0.997139453323715	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	3/3863	44/18639	0.0681818181818182	0.32897771397642	0.997209194715105	1
GO:0001637	G protein-coupled chemoattractant receptor activity	1/3863	26/18639	0.0384615384615385	0.185577171986698	0.99762584362314	1
GO:0004950	chemokine receptor activity	1/3863	26/18639	0.0384615384615385	0.185577171986698	0.99762584362314	1
GO:0015145	monosaccharide transmembrane transporter activity	1/3863	26/18639	0.0384615384615385	0.185577171986698	0.99762584362314	1
GO:0015294	solute:monoatomic cation symporter activity	13/3863	116/18639	0.112068965517241	0.540733483892276	0.99768191844602	1
GO:0004866	endopeptidase inhibitor activity	20/3863	161/18639	0.124223602484472	0.599379685919771	0.99788138984147	1
GO:0016298	lipase activity	15/3863	130/18639	0.115384615384615	0.556731515960095	0.997986320101112	1
GO:0005201	extracellular matrix structural constituent	21/3863	168/18639	0.125	0.603125808956769	0.998071414015839	1
GO:0008395	steroid hydroxylase activity	1/3863	27/18639	0.037037037037037	0.178703943394598	0.998118583433155	1
GO:0005262	calcium channel activity	15/3863	131/18639	0.114503816793893	0.552481657059636	0.998224708499194	1
GO:0008527	taste receptor activity	1/3863	28/18639	0.0357142857142857	0.172321659701934	0.998509079467849	1
GO:0008188	neuropeptide receptor activity	3/3863	48/18639	0.0625	0.301562904478385	0.998707768871819	1
GO:0005416	amino acid:monoatomic cation symporter activity	1/3863	29/18639	0.0344827586206897	0.166379533505316	0.998818543011758	1
GO:0071855	neuropeptide receptor binding	2/3863	40/18639	0.05	0.241250323582708	0.99895106280037	1
GO:0015171	amino acid transmembrane transporter activity	10/3863	102/18639	0.0980392156862745	0.473039850162172	0.99899785622295	1
GO:0015101	organic cation transmembrane transporter activity	7/3863	81/18639	0.0864197530864197	0.416975867920729	0.999042294216981	1
GO:0098918	structural constituent of synapse	1/3863	30/18639	0.0333333333333333	0.160833549055138	0.999063785803031	1
GO:0048020	CCR chemokine receptor binding	3/3863	50/18639	0.06	0.289500388299249	0.999124779681037	1
GO:0030414	peptidase inhibitor activity	20/3863	169/18639	0.118343195266272	0.571006683035995	0.999168254188134	1
GO:0046943	carboxylic acid transmembrane transporter activity	23/3863	188/18639	0.122340425531915	0.590293344936413	0.999188989637199	1
GO:0005342	organic acid transmembrane transporter activity	23/3863	189/18639	0.121693121693122	0.587170099725109	0.999276922060552	1
GO:0001664	G protein-coupled receptor binding	40/3863	297/18639	0.134680134680135	0.649832521434903	0.999574119155152	1
GO:0019825	oxygen binding	1/3863	34/18639	0.0294117647058824	0.141911955048652	0.999630900625454	1
GO:0008009	chemokine activity	2/3863	45/18639	0.0444444444444444	0.214444732073518	0.999635074020664	1
GO:0042379	chemokine receptor binding	5/3863	72/18639	0.0694444444444444	0.335069893864872	0.999674846075296	1
GO:0008201	heparin binding	19/3863	172/18639	0.11046511627907	0.53299490093854	0.999740264723179	1
GO:0003730	mRNA 3'-UTR binding	33/3863	262/18639	0.125954198473282	0.6077298227656	0.999795151066552	1
GO:0001653	peptide receptor activity	12/3863	128/18639	0.09375	0.452344356717577	0.999830465486076	1
GO:0003777	microtubule motor activity	4/3863	68/18639	0.0588235294117647	0.283823910097303	0.999854859290908	1
GO:0015370	solute:sodium symporter activity	5/3863	79/18639	0.0632911392405063	0.305380156433807	0.999909123658223	1
GO:0008236	serine-type peptidase activity	21/3863	194/18639	0.108247422680412	0.522294514972872	0.99991755524267	1
GO:0004252	serine-type endopeptidase activity	18/3863	176/18639	0.102272727272727	0.493466570964629	0.99993596850388	1
GO:0140375	immune receptor activity	15/3863	156/18639	0.0961538461538462	0.463942929966746	0.999939840889408	1
GO:0005539	glycosaminoglycan binding	28/3863	242/18639	0.115702479338843	0.558265211596349	0.99994230950227	1
GO:0004497	monooxygenase activity	8/3863	106/18639	0.0754716981132075	0.364151431822955	0.999946506191626	1
GO:0017171	serine hydrolase activity	21/3863	198/18639	0.106060606060606	0.511743110629986	0.999951004720155	1
GO:0008528	G protein-coupled peptide receptor activity	10/3863	122/18639	0.0819672131147541	0.395492333742144	0.9999537022084	1
GO:0008083	growth factor activity	15/3863	162/18639	0.0925925925925926	0.446759858486496	0.999974822083099	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/3863	46/18639	0.0217391304347826	0.10489144503596	0.999977412914099	1
GO:0005272	sodium channel activity	1/3863	51/18639	0.0196078431372549	0.0946079700324344	0.99999295200929	1
GO:0005249	voltage-gated potassium channel activity	5/3863	98/18639	0.0510204081632653	0.246173799574192	0.999997510658981	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/3863	56/18639	0.0178571428571429	0.0861608298509671	0.999997801546847	1
GO:0005244	voltage-gated monoatomic ion channel activity	14/3863	173/18639	0.0809248554913295	0.390462951463342	0.999998444157081	1
GO:0022832	voltage-gated channel activity	14/3863	175/18639	0.08	0.386000517732332	0.999998867710929	1
GO:0015079	potassium ion transmembrane transporter activity	12/3863	160/18639	0.075	0.361875485374062	0.999998888444433	1
GO:0015081	sodium ion transmembrane transporter activity	12/3863	164/18639	0.0731707317073171	0.353049254023475	0.999999427755912	1
GO:0003823	antigen binding	13/3863	174/18639	0.0747126436781609	0.360488989261517	0.999999609015008	1
GO:0046873	metal ion transmembrane transporter activity	54/3863	450/18639	0.12	0.579000776598499	0.999999671967994	1
GO:0099094	ligand-gated monoatomic cation channel activity	8/3863	136/18639	0.0588235294117647	0.283823910097303	0.999999729508144	1
GO:0098960	postsynaptic neurotransmitter receptor activity	1/3863	69/18639	0.0144927536231884	0.0699276300239733	0.999999893846488	1
GO:0005267	potassium channel activity	6/3863	124/18639	0.0483870967741935	0.23346805508004	0.999999905828465	1
GO:0022843	voltage-gated monoatomic cation channel activity	8/3863	143/18639	0.0559440559440559	0.269930431980652	0.999999925477192	1
GO:0015276	ligand-gated monoatomic ion channel activity	11/3863	186/18639	0.0591397849462366	0.285349845097826	0.999999996943183	1
GO:0022834	ligand-gated channel activity	11/3863	188/18639	0.0585106382978723	0.282314208447849	0.999999997870913	1
GO:0030594	neurotransmitter receptor activity	1/3863	97/18639	0.0103092783505155	0.0497423347593212	0.999999999845989	1
GO:0030527	structural constituent of chromatin	1/3863	98/18639	0.0102040816326531	0.0492347599148383	0.999999999878076	1
GO:0005216	monoatomic ion channel activity	43/3863	448/18639	0.0959821428571429	0.463114460448948	0.999999999948633	1
GO:0005125	cytokine activity	14/3863	234/18639	0.0598290598290598	0.288675600868197	0.999999999950082	1
GO:0005179	hormone activity	3/3863	132/18639	0.0227272727272727	0.10965923799214	0.999999999972645	1
GO:0005261	monoatomic cation channel activity	25/3863	341/18639	0.0733137829912024	0.353739477394	0.999999999998252	1
GO:0022836	gated channel activity	22/3863	318/18639	0.0691823899371069	0.333805479171042	0.999999999998314	1
GO:0030371	translation repressor activity	6/3863	329/18639	0.0182370820668693	0.0879940389967323	1	1
GO:0045182	translation regulator activity	9/3863	356/18639	0.0252808988764045	0.121980500687886	1	1