ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	153/3132	495/18639	0.309090909090909	1.83944618599791	3.32558158104599e-15	4.25341884215782e-12
GO:0051082	unfolded protein binding	57/3132	121/18639	0.471074380165289	2.80343402678826	8.48184828181957e-15	5.42414197622362e-12
GO:0043021	ribonucleoprotein complex binding	70/3132	177/18639	0.395480225988701	2.35356191960517	4.23573099745455e-13	1.80583331524812e-10
GO:0140297	DNA-binding transcription factor binding	142/3132	488/18639	0.290983606557377	1.73168692293198	5.53924789558492e-12	1.77117451461328e-09
GO:0140662	ATP-dependent protein folding chaperone	25/3132	40/18639	0.625	3.7194683908046	1.16752289075986e-10	2.98652355456372e-08
GO:0005525	GTP binding	112/3132	378/18639	0.296296296296296	1.76330353341848	3.02742402753015e-10	6.45345888535176e-08
GO:0003714	transcription corepressor activity	69/3132	204/18639	0.338235294117647	2.01288877620014	2.16655031947342e-09	3.71344309611598e-07
GO:0019001	guanyl nucleotide binding	114/3132	400/18639	0.285	1.6960775862069	2.61305612705581e-09	3.71344309611598e-07
GO:0032561	guanyl ribonucleotide binding	114/3132	400/18639	0.285	1.6960775862069	2.61305612705581e-09	3.71344309611598e-07
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	101/3132	349/18639	0.289398280802292	1.72225241247571	8.80218912439402e-09	1.12579998900999e-06
GO:0031072	heat shock protein binding	49/3132	131/18639	0.374045801526718	2.22600245678687	1.1780854974195e-08	1.36979213745413e-06
GO:0044389	ubiquitin-like protein ligase binding	93/3132	322/18639	0.288819875776398	1.71881023773827	3.75383613114038e-08	4.00096367644045e-06
GO:0019787	ubiquitin-like protein transferase activity	126/3132	479/18639	0.263048016701461	1.56543805341588	7.16873420490166e-08	7.05293157543786e-06
GO:0061650	ubiquitin-like protein conjugating enzyme activity	22/3132	41/18639	0.536585365853659	3.19329969161761	7.74169496002828e-08	7.07259132419727e-06
GO:0044183	protein folding chaperone	32/3132	75/18639	0.426666666666667	2.53915708812261	1.17442128040814e-07	1.00138987842801e-05
GO:0016755	aminoacyltransferase activity	128/3132	496/18639	0.258064516129032	1.53578049684835	1.810870496381e-07	1.44756460304456e-05
GO:0070063	RNA polymerase binding	27/3132	59/18639	0.457627118644068	2.72340736411455	2.00439402776664e-07	1.50801174206678e-05
GO:0051087	protein-folding chaperone binding	47/3132	134/18639	0.350746268656716	2.0873434551381	2.23792911664377e-07	1.59017296677076e-05
GO:0043022	ribosome binding	41/3132	112/18639	0.366071428571429	2.17854577175698	3.52332222130135e-07	2.37175216897075e-05
GO:0019003	GDP binding	31/3132	75/18639	0.413333333333333	2.45980842911877	4.34055250933124e-07	2.77578332971733e-05
GO:0031625	ubiquitin protein ligase binding	85/3132	302/18639	0.281456953642384	1.674992387912	4.80358936461246e-07	2.92561466539968e-05
GO:0004842	ubiquitin-protein transferase activity	115/3132	449/18639	0.256124721603563	1.52423648977293	1.12631502443307e-06	6.54798598295409e-05
GO:0003925	G protein activity	24/3132	54/18639	0.444444444444444	2.64495530012771	1.81705524341746e-06	0.000101044072014388
GO:0003924	GTPase activity	89/3132	331/18639	0.268882175226586	1.60015800256971	2.18831339581086e-06	0.000116618868051754
GO:0061631	ubiquitin conjugating enzyme activity	18/3132	35/18639	0.514285714285714	3.06059113300493	2.68317465933921e-06	0.000137271215571794
GO:0003727	single-stranded RNA binding	33/3132	89/18639	0.370786516853933	2.20660596667958	3.43244915268782e-06	0.00016885009485722
GO:0060590	ATPase regulator activity	22/3132	49/18639	0.448979591836735	2.67194463992494	3.95651078652267e-06	0.000187421381331944
GO:0003725	double-stranded RNA binding	29/3132	75/18639	0.386666666666667	2.30111111111111	5.0545812754202e-06	0.000230886051830801
GO:0045296	cadherin binding	88/3132	334/18639	0.263473053892216	1.56796751324936	6.03392736363995e-06	0.000266117003382604
GO:0003713	transcription coactivator activity	71/3132	256/18639	0.27734375	1.65051409841954	7.14374329453118e-06	0.000304561589123512
GO:0051537	2 iron, 2 sulfur cluster binding	15/3132	28/18639	0.535714285714286	3.1881157635468	9.62149745375664e-06	0.000396964362688862
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	41/3132	128/18639	0.3203125	1.90622755028736	1.6796787402175e-05	0.000671346596480681
GO:0003697	single-stranded DNA binding	39/3132	121/18639	0.322314049586777	1.91813907096039	2.27463283146281e-05	0.000881592542860887
GO:0002039	p53 binding	26/3132	69/18639	0.376811594202899	2.24246210228219	2.61820556715006e-05	0.000984907329524978
GO:0000287	magnesium ion binding	63/3132	230/18639	0.273913043478261	1.63009745127436	3.44912168848185e-05	0.00126040761130522
GO:0015035	protein-disulfide reductase activity	16/3132	34/18639	0.470588235294118	2.80054090601758	4.0224421080029e-05	0.00142908429337103
GO:0061659	ubiquitin-like protein ligase activity	92/3132	372/18639	0.247311827956989	1.471789642813	5.42148927814509e-05	0.00178814609692313
GO:0001098	basal transcription machinery binding	23/3132	60/18639	0.383333333333333	2.28127394636015	5.49916201943444e-05	0.00178814609692313
GO:0001099	basal RNA polymerase II transcription machinery binding	23/3132	60/18639	0.383333333333333	2.28127394636015	5.49916201943444e-05	0.00178814609692313
GO:0140098	catalytic activity, acting on RNA	95/3132	387/18639	0.245478036175711	1.46087647390775	5.59232555722636e-05	0.00178814609692313
GO:0003756	protein disulfide isomerase activity	11/3132	19/18639	0.578947368421053	3.44540229885057	5.95611336752901e-05	0.00181377833263562
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	11/3132	19/18639	0.578947368421053	3.44540229885057	5.95611336752901e-05	0.00181377833263562
GO:0043175	RNA polymerase core enzyme binding	18/3132	42/18639	0.428571428571429	2.55049261083744	6.34779531269937e-05	0.00188810004766104
GO:0140104	molecular carrier activity	66/3132	249/18639	0.265060240963855	1.57741310067858	6.84142551991372e-05	0.00198867800908401
GO:0051059	NF-kappaB binding	15/3132	32/18639	0.46875	2.78960129310345	7.40757233894209e-05	0.00210539667144599
GO:0043539	protein serine/threonine kinase activator activity	26/3132	73/18639	0.356164383561644	2.1195874665407	8.01204734420614e-05	0.00219742989363802
GO:0019887	protein kinase regulator activity	67/3132	255/18639	0.262745098039216	1.56363533919315	8.07499648170342e-05	0.00219742989363802
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	21/3132	54/18639	0.388888888888889	2.31433588761175	8.97709789470541e-05	0.00239202254319338
GO:0000993	RNA polymerase II complex binding	16/3132	36/18639	0.444444444444444	2.64495530012771	9.51475252299559e-05	0.00246145043438073
GO:0016922	nuclear receptor binding	41/3132	137/18639	0.299270072992701	1.78100092289622	9.62255838303649e-05	0.00246145043438073
GO:0004532	RNA exonuclease activity	17/3132	40/18639	0.425	2.52923850574713	0.000114587918347119	0.00287368524639147
GO:0019207	kinase regulator activity	73/3132	287/18639	0.254355400696864	1.51370699667588	0.000121596585802102	0.00299080833155554
GO:0016887	ATP hydrolysis activity	99/3132	417/18639	0.237410071942446	1.41286281319772	0.00015278306232908	0.0036869723909225
GO:0001671	ATPase activator activity	13/3132	27/18639	0.481481481481481	2.86536824180502	0.000159605508948023	0.00378028603600967
GO:0000774	adenyl-nucleotide exchange factor activity	9/3132	15/18639	0.6	3.57068965517241	0.000199424964465694	0.00463753690093859
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	16/3132	38/18639	0.421052631578947	2.50574712643678	0.000206703508397607	0.00472093428164523
GO:0001221	transcription coregulator binding	35/3132	115/18639	0.304347826086957	1.81121939030485	0.00021039347463157	0.00472093428164523
GO:0009055	electron transfer activity	35/3132	116/18639	0.301724137931034	1.7956054300436	0.000253275923503557	0.00557048923119972
GO:0000175	3'-5'-RNA exonuclease activity	15/3132	35/18639	0.428571428571429	2.55049261083744	0.000256965492291465	0.00557048923119972
GO:0061630	ubiquitin protein ligase activity	85/3132	353/18639	0.240793201133144	1.43299632053662	0.000265354045663828	0.00565646374006727
GO:0005048	signal sequence binding	19/3132	51/18639	0.372549019607843	2.21709488393058	0.000367636207879384	0.00744517399965139
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	15/3132	36/18639	0.416666666666667	2.47964559386973	0.000372549754478256	0.00744517399965139
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	15/3132	36/18639	0.416666666666667	2.47964559386973	0.000372549754478256	0.00744517399965139
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	15/3132	36/18639	0.416666666666667	2.47964559386973	0.000372549754478256	0.00744517399965139
GO:0004527	exonuclease activity	27/3132	84/18639	0.321428571428571	1.91286945812808	0.000411524521154706	0.00808659173067047
GO:0015036	disulfide oxidoreductase activity	16/3132	40/18639	0.4	2.38045977011494	0.000417290894624121	0.00808659173067047
GO:0051536	iron-sulfur cluster binding	25/3132	76/18639	0.328947368421053	1.95761494252874	0.0004490677739111	0.00857250272884026
GO:0097602	cullin family protein binding	12/3132	26/18639	0.461538461538462	2.74668435013263	0.000466733085009793	0.00877870023128714
GO:0032182	ubiquitin-like protein binding	35/3132	120/18639	0.291666666666667	1.73575191570881	0.000513377075029053	0.00951607650669795
GO:0051540	metal cluster binding	25/3132	77/18639	0.324675324675325	1.93219137184654	0.000560216311491476	0.0102359523199657
GO:0019209	kinase activator activity	41/3132	148/18639	0.277027027027027	1.64862923268096	0.000582974001750247	0.0105017429329375
GO:0016860	intramolecular oxidoreductase activity	19/3132	53/18639	0.358490566037736	2.13343092604641	0.00064349774808267	0.0114310224971908
GO:0051787	misfolded protein binding	9/3132	17/18639	0.529411764705882	3.15060851926978	0.000701446865755674	0.0122897334424864
GO:0016859	cis-trans isomerase activity	16/3132	42/18639	0.380952380952381	2.26710454296661	0.000790270256434172	0.0134767421063907
GO:0051879	Hsp90 protein binding	16/3132	42/18639	0.380952380952381	2.26710454296661	0.000790270256434172	0.0134767421063907
GO:0008408	3'-5' exonuclease activity	20/3132	58/18639	0.344827586206897	2.0521204914784	0.000829565066630358	0.0136079864323132
GO:0051020	GTPase binding	75/3132	315/18639	0.238095238095238	1.41694033935413	0.000829884621609823	0.0136079864323132
GO:0140597	protein carrier chaperone	49/3132	188/18639	0.26063829787234	1.55109745659085	0.000829885020891658	0.0136079864323132
GO:0042393	histone binding	61/3132	247/18639	0.246963562753036	1.46971706454465	0.000940212467627567	0.0152219208366539
GO:0003735	structural constituent of ribosome	46/3132	175/18639	0.262857142857143	1.56430213464696	0.000970876298210786	0.0155218848176449
GO:0051117	ATPase binding	26/3132	84/18639	0.30952380952381	1.84202244116037	0.00098680233210967	0.0155817306514601
GO:0016853	isomerase activity	47/3132	180/18639	0.261111111111111	1.55391123882503	0.00100385846307902	0.0156577435887569
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	15/3132	39/18639	0.384615384615385	2.28890362511052	0.00101873461380241	0.0156983321813648
GO:0030544	Hsp70 protein binding	18/3132	51/18639	0.352941176470588	2.10040567951318	0.00109199836316568	0.0166269750772489
GO:1990381	ubiquitin-specific protease binding	9/3132	18/18639	0.5	2.97557471264368	0.00119449022025312	0.0177309278237733
GO:0030515	snoRNA binding	13/3132	32/18639	0.40625	2.41765445402299	0.00120609125931843	0.0177309278237733
GO:0140142	nucleocytoplasmic carrier activity	13/3132	32/18639	0.40625	2.41765445402299	0.00120609125931843	0.0177309278237733
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	22/3132	68/18639	0.323529411764706	1.92537187288709	0.00123539629463758	0.0179553620550167
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	20/3132	60/18639	0.333333333333333	1.98371647509579	0.00134150598618354	0.0192784961385253
GO:0001046	core promoter sequence-specific DNA binding	16/3132	44/18639	0.363636363636364	2.16405433646813	0.00141487081856038	0.0198859316147113
GO:0003954	NADH dehydrogenase activity	16/3132	44/18639	0.363636363636364	2.16405433646813	0.00141487081856038	0.0198859316147113
GO:0070034	telomerase RNA binding	10/3132	22/18639	0.454545454545455	2.70506792058516	0.00160759243680584	0.021996630677986
GO:0019843	rRNA binding	21/3132	65/18639	0.323076923076923	1.92267904509284	0.00161035008776818	0.021996630677986
GO:0003689	DNA clamp loader activity	42/3132	160/18639	0.2625	1.56217672413793	0.00161664056585667	0.021996630677986
GO:0031267	small GTPase binding	67/3132	283/18639	0.236749116607774	1.40892936923764	0.00176976012615408	0.0238135948697524
GO:0140296	general transcription initiation factor binding	18/3132	53/18639	0.339622641509434	2.02114508783344	0.0018060785831872	0.0238135948697524
GO:0008137	NADH dehydrogenase (ubiquinone) activity	15/3132	41/18639	0.365853658536585	2.17724978973928	0.00184173743629161	0.0238135948697524
GO:0140318	protein transporter activity	15/3132	41/18639	0.365853658536585	2.17724978973928	0.00184173743629161	0.0238135948697524
GO:0001222	transcription corepressor binding	17/3132	49/18639	0.346938775510204	2.06468449448745	0.00184327278507075	0.0238135948697524
GO:0050681	nuclear androgen receptor binding	11/3132	26/18639	0.423076923076923	2.51779398762157	0.00193204947674007	0.0247109128075054
GO:0046332	SMAD binding	24/3132	79/18639	0.30379746835443	1.80794412920122	0.00201114487379267	0.0254678642928794
GO:0016741	transferase activity, transferring one-carbon groups	53/3132	215/18639	0.246511627906977	1.46702753274526	0.00203459827933643	0.0255122666595225
GO:0070566	adenylyltransferase activity	12/3132	30/18639	0.4	2.38045977011494	0.00216516633616939	0.0268859004268024
GO:0030295	protein kinase activator activity	37/3132	139/18639	0.266187050359712	1.58411891176714	0.00227939365332004	0.0280321584865032
GO:0004402	histone acetyltransferase activity	15/3132	42/18639	0.357142857142857	2.1254105090312	0.00242588586954574	0.0295496002585619
GO:0005528	FK506 binding	6/3132	10/18639	0.6	3.57068965517241	0.00253936048442974	0.0306400194300532
GO:0019208	phosphatase regulator activity	32/3132	117/18639	0.273504273504274	1.62766480007859	0.00275242907257219	0.0329005306899049
GO:0004386	helicase activity	40/3132	155/18639	0.258064516129032	1.53578049684835	0.00286805489669703	0.0334075954479124
GO:0043024	ribosomal small subunit binding	9/3132	20/18639	0.45	2.67801724137931	0.00299496603206072	0.0334075954479124
GO:0052745	inositol phosphate phosphatase activity	9/3132	20/18639	0.45	2.67801724137931	0.00299496603206072	0.0334075954479124
GO:0005548	phospholipid transporter activity	21/3132	68/18639	0.308823529411765	1.83785496957404	0.00299504470859177	0.0334075954479124
GO:1990841	promoter-specific chromatin binding	21/3132	68/18639	0.308823529411765	1.83785496957404	0.00299504470859177	0.0334075954479124
GO:0070273	phosphatidylinositol-4-phosphate binding	12/3132	31/18639	0.387096774193548	2.30367074527252	0.00299900958140563	0.0334075954479124
GO:0061733	protein-lysine-acetyltransferase activity	16/3132	47/18639	0.340425531914894	2.02592320860846	0.00309283673093663	0.0334075954479124
GO:0010485	histone H4 acetyltransferase activity	13/3132	35/18639	0.371428571428571	2.21042692939245	0.00312562045079059	0.0334075954479124
GO:0003724	RNA helicase activity	23/3132	77/18639	0.298701298701299	1.77761606209882	0.00313716163494724	0.0334075954479124
GO:0048156	tau protein binding	15/3132	43/18639	0.348837209302326	2.07598235765838	0.00315524687509292	0.0334075954479124
GO:0000510	H3-H4 histone complex chaperone activity	39/3132	151/18639	0.258278145695364	1.53705183831925	0.00316053092196826	0.0334075954479124
GO:0140584	chromatin extrusion motor activity	39/3132	151/18639	0.258278145695364	1.53705183831925	0.00316053092196826	0.0334075954479124
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	39/3132	151/18639	0.258278145695364	1.53705183831925	0.00316053092196826	0.0334075954479124
GO:0140849	ATP-dependent H2AZ histone chaperone activity	39/3132	151/18639	0.258278145695364	1.53705183831925	0.00316053092196826	0.0334075954479124
GO:0008094	ATP-dependent activity, acting on DNA	51/3132	210/18639	0.242857142857143	1.44527914614122	0.00338911674039951	0.0355301664833686
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	24/3132	82/18639	0.292682926829268	1.74179983179142	0.00346437890710732	0.0360239074974818
GO:0015616	DNA translocase activity	39/3132	152/18639	0.256578947368421	1.52693965517241	0.0035760191539243	0.0365898279829534
GO:0140674	ATP-dependent histone chaperone activity	39/3132	152/18639	0.256578947368421	1.52693965517241	0.0035760191539243	0.0365898279829534
GO:0070402	NADPH binding	8/3132	17/18639	0.470588235294118	2.80054090601758	0.00364045241871707	0.0369534812979296
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	42/3132	167/18639	0.251497005988024	1.49669626264712	0.00380807152458402	0.038350578582228
GO:0036408	histone H3K14 acetyltransferase activity	11/3132	28/18639	0.392857142857143	2.33795155993432	0.00387893421968973	0.038759038023306
GO:0061775	cohesin loader activity	39/3132	153/18639	0.254901960784314	1.51695965742619	0.00403731814548459	0.0397833494273855
GO:0003684	damaged DNA binding	22/3132	74/18639	0.297297297297297	1.7692606399503	0.00406266904531358	0.0397833494273855
GO:0070717	poly-purine tract binding	12/3132	32/18639	0.375	2.23168103448276	0.00407476057465794	0.0397833494273855
GO:0140658	ATP-dependent chromatin remodeler activity	40/3132	158/18639	0.253164556962025	1.50662010766769	0.00412304952919896	0.0399158545526207
GO:0055106	ubiquitin-protein transferase regulator activity	13/3132	36/18639	0.361111111111111	2.14902618135377	0.0041507495351826	0.0399158545526207
GO:0030983	mismatched DNA binding	7/3132	14/18639	0.5	2.97557471264368	0.00429380806178773	0.0409834366494516
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9/3132	21/18639	0.428571428571429	2.55049261083744	0.00446785886415601	0.0414365436472404
GO:0051010	microtubule plus-end binding	9/3132	21/18639	0.428571428571429	2.55049261083744	0.00446785886415601	0.0414365436472404
GO:0072542	protein phosphatase activator activity	9/3132	21/18639	0.428571428571429	2.55049261083744	0.00446785886415601	0.0414365436472404
GO:0008186	ATP-dependent activity, acting on RNA	23/3132	79/18639	0.291139240506329	1.73261312381784	0.00447087022933477	0.0414365436472404
GO:0034212	protein N-acetyltransferase activity	17/3132	53/18639	0.320754716981132	1.90885924962047	0.0046933098321017	0.043033999990585
GO:0140713	histone chaperone activity	41/3132	164/18639	0.25	1.48778735632184	0.00471052384572471	0.043033999990585
GO:0070990	snRNP binding	6/3132	11/18639	0.545454545454545	3.24608150470219	0.00479485511758487	0.0430773972260909
GO:0140537	transcription regulator activator activity	6/3132	11/18639	0.545454545454545	3.24608150470219	0.00479485511758487	0.0430773972260909
GO:0004540	RNA nuclease activity	32/3132	121/18639	0.264462809917355	1.57385769924955	0.00481631571800703	0.0430773972260909
GO:0019888	protein phosphatase regulator activity	29/3132	107/18639	0.271028037383178	1.61292834890966	0.0048664109908951	0.0432231920649641
GO:0019211	phosphatase activator activity	10/3132	25/18639	0.4	2.38045977011494	0.0050083257413084	0.0441768870560927
GO:0008168	methyltransferase activity	49/3132	204/18639	0.240196078431373	1.42944275411314	0.00504300097439407	0.0441780701797946
GO:0010484	histone H3 acetyltransferase activity	11/3132	29/18639	0.379310344827586	2.25733254062624	0.00531397323632341	0.0462351821037935
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	18/3132	58/18639	0.310344827586207	1.84690844233056	0.00543713070178884	0.0466889456458393
GO:0140416	transcription regulator inhibitor activity	12/3132	33/18639	0.363636363636364	2.16405433646813	0.0054391344028382	0.0466889456458393
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	8/3132	18/18639	0.444444444444444	2.64495530012771	0.00559722217748824	0.0477256477667164
GO:0017069	snRNA binding	17/3132	54/18639	0.314814814814815	1.87351000425713	0.00579754409893325	0.049106350347918
GO:0033192	calmodulin-dependent protein phosphatase activity	23/3132	81/18639	0.283950617283951	1.68983255285937	0.00624588816676935	0.0502420815427547
GO:0140791	histone H2AXS140 phosphatase activity	23/3132	81/18639	0.283950617283951	1.68983255285937	0.00624588816676935	0.0502420815427547
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	23/3132	81/18639	0.283950617283951	1.68983255285937	0.00624588816676935	0.0502420815427547
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	23/3132	81/18639	0.283950617283951	1.68983255285937	0.00624588816676935	0.0502420815427547
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	23/3132	81/18639	0.283950617283951	1.68983255285937	0.00624588816676935	0.0502420815427547
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	23/3132	81/18639	0.283950617283951	1.68983255285937	0.00624588816676935	0.0502420815427547
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	23/3132	81/18639	0.283950617283951	1.68983255285937	0.00624588816676935	0.0502420815427547
GO:1990439	MAP kinase serine/threonine phosphatase activity	23/3132	81/18639	0.283950617283951	1.68983255285937	0.00624588816676935	0.0502420815427547
GO:0140517	protein-RNA adaptor activity	9/3132	22/18639	0.409090909090909	2.43456112852665	0.00644804331385996	0.0513246635983739
GO:0008276	protein methyltransferase activity	26/3132	95/18639	0.273684210526316	1.62873563218391	0.00646072778681642	0.0513246635983739
GO:0043130	ubiquitin binding	27/3132	100/18639	0.27	1.60681034482759	0.00679226291689772	0.0535103596566092
GO:0140223	general transcription initiation factor activity	20/3132	68/18639	0.294117647058824	1.75033806626099	0.00681953762629187	0.0535103596566092
GO:0008143	poly(A) binding	10/3132	26/18639	0.384615384615385	2.28890362511052	0.00693099840666359	0.0540129018667584
GO:0008187	poly-pyrimidine tract binding	11/3132	30/18639	0.366666666666667	2.18208812260536	0.0071369667048336	0.0540129018667584
GO:0035925	mRNA 3'-UTR AU-rich region binding	11/3132	30/18639	0.366666666666667	2.18208812260536	0.0071369667048336	0.0540129018667584
GO:0043995	histone H4K5 acetyltransferase activity	11/3132	30/18639	0.366666666666667	2.18208812260536	0.0071369667048336	0.0540129018667584
GO:0043996	histone H4K8 acetyltransferase activity	11/3132	30/18639	0.366666666666667	2.18208812260536	0.0071369667048336	0.0540129018667584
GO:0043997	histone H4K12 acetyltransferase activity	11/3132	30/18639	0.366666666666667	2.18208812260536	0.0071369667048336	0.0540129018667584
GO:0033549	MAP kinase phosphatase activity	23/3132	82/18639	0.280487804878049	1.66922483880011	0.00733020533579016	0.0551490154380919
GO:0140097	catalytic activity, acting on DNA	74/3132	336/18639	0.220238095238095	1.31066981390257	0.00741308986761388	0.055446444097533
GO:0005049	nuclear export signal receptor activity	6/3132	12/18639	0.5	2.97557471264368	0.00823601408826413	0.060193497250799
GO:0005527	macrolide binding	6/3132	12/18639	0.5	2.97557471264368	0.00823601408826413	0.060193497250799
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	6/3132	12/18639	0.5	2.97557471264368	0.00823601408826413	0.060193497250799
GO:1990817	poly(A) RNA polymerase activity	6/3132	12/18639	0.5	2.97557471264368	0.00823601408826413	0.060193497250799
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	23/3132	83/18639	0.27710843373494	1.64911369616397	0.00856383109553647	0.0618821467298935
GO:0008135	translation factor activity, RNA binding	23/3132	83/18639	0.27710843373494	1.64911369616397	0.00856383109553647	0.0618821467298935
GO:0044013	histone H2B acetyltransferase activity	9/3132	23/18639	0.391304347826087	2.32871064467766	0.00903777126220861	0.0649399406986788
GO:0008266	poly(U) RNA binding	10/3132	27/18639	0.37037037037037	2.20412941677309	0.00937833021692416	0.0670105270807039
GO:0017018	myosin phosphatase activity	23/3132	84/18639	0.273809523809524	1.62948139025725	0.00996113692052391	0.0703883653113264
GO:0180051	translation factor activity	23/3132	84/18639	0.273809523809524	1.62948139025725	0.00996113692052391	0.0703883653113264
GO:0030275	LRR domain binding	7/3132	16/18639	0.4375	2.60362787356322	0.0104995519853687	0.073785313127948
GO:0001223	transcription coactivator binding	14/3132	44/18639	0.318181818181818	1.89354754440961	0.0106094425512587	0.0741501476669939
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	13/3132	40/18639	0.325	1.93412356321839	0.0112309274910168	0.0772277218333899
GO:0061791	GTPase motor activity	13/3132	40/18639	0.325	1.93412356321839	0.0112309274910168	0.0772277218333899
GO:1990606	membrane scission GTPase motor activity	13/3132	40/18639	0.325	1.93412356321839	0.0112309274910168	0.0772277218333899
GO:0044390	ubiquitin-like protein conjugating enzyme binding	12/3132	36/18639	0.333333333333333	1.98371647509579	0.0117820470076471	0.0805841610843887
GO:0035035	histone acetyltransferase binding	9/3132	24/18639	0.375	2.23168103448276	0.0123425308503286	0.0839686008381397
GO:0097718	disordered domain specific binding	10/3132	28/18639	0.357142857142857	2.1254105090312	0.0124335502153877	0.0841402683887877
GO:0004518	nuclease activity	48/3132	209/18639	0.229665071770335	1.36677115987461	0.0128828013014308	0.086721594023842
GO:0004535	poly(A)-specific ribonuclease activity	6/3132	13/18639	0.461538461538462	2.74668435013263	0.0131451464725449	0.0875658455124216
GO:0019104	DNA N-glycosylase activity	6/3132	13/18639	0.461538461538462	2.74668435013263	0.0131451464725449	0.0875658455124216
GO:0140463	chromatin-protein adaptor activity	16/3132	54/18639	0.296296296296296	1.76330353341848	0.0135880246562076	0.0900470649496866
GO:0001217	DNA-binding transcription repressor activity	61/3132	278/18639	0.219424460431655	1.30582775159183	0.0150697841367299	0.0993518242828738
GO:0004029	aldehyde dehydrogenase (NAD+) activity	7/3132	17/18639	0.411764705882353	2.45047329276538	0.0153009216820248	0.100358352981075
GO:0071889	14-3-3 protein binding	11/3132	33/18639	0.333333333333333	1.98371647509579	0.0155939051989931	0.101758187497511
GO:0035091	phosphatidylinositol binding	62/3132	284/18639	0.21830985915493	1.29919459284442	0.0159447434749129	0.103201061942972
GO:0008641	ubiquitin-like modifier activating enzyme activity	5/3132	10/18639	0.5	2.97557471264368	0.0159763958285445	0.103201061942972
GO:0106222	lncRNA binding	10/3132	29/18639	0.344827586206897	2.0521204914784	0.0161806959938426	0.10399552852324
GO:0008139	nuclear localization sequence binding	9/3132	25/18639	0.36	2.14241379310345	0.0164680212241524	0.104789050476074
GO:0017025	TBP-class protein binding	9/3132	25/18639	0.36	2.14241379310345	0.0164680212241524	0.104789050476074
GO:0008080	N-acetyltransferase activity	19/3132	69/18639	0.27536231884058	1.63872230551391	0.0170234216872419	0.107786912564269
GO:0048487	beta-tubulin binding	13/3132	42/18639	0.30952380952381	1.84202244116037	0.0171984663707982	0.10835881028695
GO:0003743	translation initiation factor activity	15/3132	51/18639	0.294117647058824	1.75033806626099	0.0177279259149524	0.111147143358942
GO:0004722	protein serine/threonine phosphatase activity	26/3132	103/18639	0.252427184466019	1.50223189376186	0.0188098566801163	0.117355154604238
GO:0140030	modification-dependent protein binding	40/3132	173/18639	0.23121387283237	1.37598830642482	0.0194904832097097	0.121011301093294
GO:0008175	tRNA methyltransferase activity	11/3132	34/18639	0.323529411764706	1.92537187288709	0.0196358759600918	0.121325050014287
GO:1990825	sequence-specific mRNA binding	6/3132	14/18639	0.428571428571429	2.55049261083744	0.0197836502806128	0.121650426485115
GO:0017128	phospholipid scramblase activity	7/3132	18/18639	0.388888888888889	2.31433588761175	0.0214760031849116	0.124382072246282
GO:0070064	proline-rich region binding	7/3132	18/18639	0.388888888888889	2.31433588761175	0.0214760031849116	0.124382072246282
GO:0070628	proteasome binding	7/3132	18/18639	0.388888888888889	2.31433588761175	0.0214760031849116	0.124382072246282
GO:0070412	R-SMAD binding	9/3132	26/18639	0.346153846153846	2.06001326259947	0.0215170333039994	0.124382072246282
GO:0120014	phospholipid transfer activity	9/3132	26/18639	0.346153846153846	2.06001326259947	0.0215170333039994	0.124382072246282
GO:0032931	histone H3K56 acetyltransferase activity	8/3132	22/18639	0.363636363636364	2.16405433646813	0.0218811307704562	0.124382072246282
GO:0043992	histone H3K9 acetyltransferase activity	8/3132	22/18639	0.363636363636364	2.16405433646813	0.0218811307704562	0.124382072246282
GO:0043993	histone H3K18 acetyltransferase activity	8/3132	22/18639	0.363636363636364	2.16405433646813	0.0218811307704562	0.124382072246282
GO:0043994	histone H3K23 acetyltransferase activity	8/3132	22/18639	0.363636363636364	2.16405433646813	0.0218811307704562	0.124382072246282
GO:0043999	histone H2AK5 acetyltransferase activity	8/3132	22/18639	0.363636363636364	2.16405433646813	0.0218811307704562	0.124382072246282
GO:0044012	histone H2AK9 acetyltransferase activity	8/3132	22/18639	0.363636363636364	2.16405433646813	0.0218811307704562	0.124382072246282
GO:0044014	histone H2BK5 acetyltransferase activity	8/3132	22/18639	0.363636363636364	2.16405433646813	0.0218811307704562	0.124382072246282
GO:0044015	histone H2BK12 acetyltransferase activity	8/3132	22/18639	0.363636363636364	2.16405433646813	0.0218811307704562	0.124382072246282
GO:0044016	histone H3K4 acetyltransferase activity	8/3132	22/18639	0.363636363636364	2.16405433646813	0.0218811307704562	0.124382072246282
GO:0044017	histone H3K27 acetyltransferase activity	8/3132	22/18639	0.363636363636364	2.16405433646813	0.0218811307704562	0.124382072246282
GO:0044018	histone H3K36 acetyltransferase activity	8/3132	22/18639	0.363636363636364	2.16405433646813	0.0218811307704562	0.124382072246282
GO:0140908	histone H3K122 acetyltransferase activity	8/3132	22/18639	0.363636363636364	2.16405433646813	0.0218811307704562	0.124382072246282
GO:0140767	enzyme-substrate adaptor activity	33/3132	139/18639	0.237410071942446	1.41286281319772	0.022055023392898	0.124815818227949
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	58/3132	268/18639	0.216417910447761	1.28793532338308	0.0226477762702537	0.12760575264165
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	14/3132	48/18639	0.291666666666667	1.73575191570881	0.0231506277746092	0.129299794426748
GO:0140693	molecular condensate scaffold activity	14/3132	48/18639	0.291666666666667	1.73575191570881	0.0231506277746092	0.129299794426748
GO:0016251	RNA polymerase II general transcription initiation factor activity	15/3132	53/18639	0.283018867924528	1.68428757319453	0.0250435736756091	0.136661289531412
GO:0008526	phosphatidylinositol transfer activity	5/3132	11/18639	0.454545454545455	2.70506792058516	0.0252943464210109	0.136661289531412
GO:0010854	adenylate cyclase regulator activity	5/3132	11/18639	0.454545454545455	2.70506792058516	0.0252943464210109	0.136661289531412
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	5/3132	11/18639	0.454545454545455	2.70506792058516	0.0252943464210109	0.136661289531412
GO:0019107	myristoyltransferase activity	5/3132	11/18639	0.454545454545455	2.70506792058516	0.0252943464210109	0.136661289531412
GO:0032404	mismatch repair complex binding	5/3132	11/18639	0.454545454545455	2.70506792058516	0.0252943464210109	0.136661289531412
GO:0034511	U3 snoRNA binding	5/3132	11/18639	0.454545454545455	2.70506792058516	0.0252943464210109	0.136661289531412
GO:0008173	RNA methyltransferase activity	18/3132	67/18639	0.26865671641791	1.59881626351004	0.0253234758553124	0.136661289531412
GO:0061980	regulatory RNA binding	16/3132	58/18639	0.275862068965517	1.64169639318272	0.0266633518768628	0.143287508615578
GO:0016779	nucleotidyltransferase activity	32/3132	136/18639	0.235294117647059	1.40027045300879	0.0269023899370423	0.143967182968523
GO:0008320	protein transmembrane transporter activity	9/3132	27/18639	0.333333333333333	1.98371647509579	0.027586384847537	0.147012442583333
GO:0005158	insulin receptor binding	8/3132	23/18639	0.347826086956522	2.06996501749125	0.0287309225081882	0.151846487140383
GO:0008171	O-methyltransferase activity	8/3132	23/18639	0.347826086956522	2.06996501749125	0.0287309225081882	0.151846487140383
GO:0097001	ceramide binding	7/3132	19/18639	0.368421052631579	2.19252873563218	0.0291841603436628	0.15303023998204
GO:0030145	manganese ion binding	18/3132	68/18639	0.264705882352941	1.57530425963489	0.0291941974633447	0.15303023998204
GO:0042826	histone deacetylase binding	30/3132	127/18639	0.236220472440945	1.40578332880804	0.02984161961472	0.155785434641742
GO:0036002	pre-mRNA binding	16/3132	59/18639	0.271186440677966	1.6138710305864	0.031052324640278	0.161446842337055
GO:0016791	phosphatase activity	58/3132	273/18639	0.212454212454212	1.26434676434676	0.031733357473132	0.164319693150348
GO:0022884	macromolecule transmembrane transporter activity	10/3132	32/18639	0.3125	1.8597341954023	0.0323829961426679	0.166197384859606
GO:0043425	bHLH transcription factor binding	10/3132	32/18639	0.3125	1.8597341954023	0.0323829961426679	0.166197384859606
GO:0051219	phosphoprotein binding	23/3132	93/18639	0.247311827956989	1.471789642813	0.0324858062665375	0.166197384859606
GO:0008170	N-methyltransferase activity	24/3132	98/18639	0.244897959183673	1.45742434904996	0.0327718264019634	0.166992693100044
GO:0031491	nucleosome binding	19/3132	74/18639	0.256756756756757	1.52799782541162	0.0343863589703241	0.174524417154938
GO:1901981	phosphatidylinositol phosphate binding	41/3132	185/18639	0.221621621621622	1.31890338614477	0.0347635838098487	0.175052013599392
GO:0019789	SUMO transferase activity	9/3132	28/18639	0.321428571428571	1.91286945812808	0.0347640433575025	0.175052013599392
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	13/3132	46/18639	0.282608695652174	1.68184657671164	0.0358985585860431	0.180055907574702
GO:0035591	signaling adaptor activity	30/3132	129/18639	0.232558139534884	1.38398823843892	0.0362025812305068	0.180871489819603
GO:0106310	protein serine kinase activity	74/3132	361/18639	0.204986149584488	1.21990320629159	0.0364459080616755	0.181378663077366
GO:0001091	RNA polymerase II general transcription initiation factor binding	8/3132	24/18639	0.333333333333333	1.98371647509579	0.0369251183371182	0.18157376557101
GO:0043998	histone H2A acetyltransferase activity	8/3132	24/18639	0.333333333333333	1.98371647509579	0.0369251183371182	0.18157376557101
GO:0000340	RNA 7-methylguanosine cap binding	5/3132	12/18639	0.416666666666667	2.47964559386973	0.0374788695158301	0.18157376557101
GO:0003995	acyl-CoA dehydrogenase activity	5/3132	12/18639	0.416666666666667	2.47964559386973	0.0374788695158301	0.18157376557101
GO:0016423	tRNA (guanine) methyltransferase activity	5/3132	12/18639	0.416666666666667	2.47964559386973	0.0374788695158301	0.18157376557101
GO:0043047	single-stranded telomeric DNA binding	5/3132	12/18639	0.416666666666667	2.47964559386973	0.0374788695158301	0.18157376557101
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	5/3132	12/18639	0.416666666666667	2.47964559386973	0.0374788695158301	0.18157376557101
GO:0000339	RNA cap binding	7/3132	20/18639	0.35	2.08290229885057	0.0385591913620965	0.183872657129139
GO:0030742	GTP-dependent protein binding	7/3132	20/18639	0.35	2.08290229885057	0.0385591913620965	0.183872657129139
GO:0061608	nuclear import signal receptor activity	7/3132	20/18639	0.35	2.08290229885057	0.0385591913620965	0.183872657129139
GO:0005521	lamin binding	6/3132	16/18639	0.375	2.23168103448276	0.0391034892409114	0.183872657129139
GO:0017070	U6 snRNA binding	6/3132	16/18639	0.375	2.23168103448276	0.0391034892409114	0.183872657129139
GO:0043023	ribosomal large subunit binding	6/3132	16/18639	0.375	2.23168103448276	0.0391034892409114	0.183872657129139
GO:0070411	I-SMAD binding	6/3132	16/18639	0.375	2.23168103448276	0.0391034892409114	0.183872657129139
GO:0097027	ubiquitin-protein transferase activator activity	6/3132	16/18639	0.375	2.23168103448276	0.0391034892409114	0.183872657129139
GO:0140789	histone phosphatase activity	31/3132	136/18639	0.227941176470588	1.35651200135226	0.0430923855721097	0.200577661925091
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	9/3132	29/18639	0.310344827586207	1.84690844233056	0.0431265496711493	0.200577661925091
GO:0097472	cyclin-dependent protein kinase activity	9/3132	29/18639	0.310344827586207	1.84690844233056	0.0431265496711493	0.200577661925091
GO:0042162	telomeric DNA binding	11/3132	38/18639	0.289473684210526	1.72270114942529	0.043649225726883	0.202273042408273
GO:0016407	acetyltransferase activity	23/3132	96/18639	0.239583333333333	1.4257962164751	0.0452306316287684	0.208844685390595
GO:0019902	phosphatase binding	41/3132	190/18639	0.215789473684211	1.28419540229885	0.0505884179195959	0.232743116975407
GO:0005092	GDP-dissociation inhibitor activity	6/3132	17/18639	0.352941176470588	2.10040567951318	0.0520867079093951	0.238340658821132
GO:0097157	pre-mRNA intronic binding	5/3132	13/18639	0.384615384615385	2.28890362511052	0.0526874464178832	0.238340658821132
GO:0140666	annealing activity	5/3132	13/18639	0.384615384615385	2.28890362511052	0.0526874464178832	0.238340658821132
GO:0140852	histone ubiquitin ligase activity	5/3132	13/18639	0.384615384615385	2.28890362511052	0.0526874464178832	0.238340658821132
GO:0031624	ubiquitin conjugating enzyme binding	9/3132	30/18639	0.3	1.78534482758621	0.0527368306852074	0.238340658821132
GO:0004721	phosphoprotein phosphatase activity	38/3132	175/18639	0.217142857142857	1.29224958949097	0.0535060831570034	0.240965775907772
GO:0043014	alpha-tubulin binding	12/3132	44/18639	0.272727272727273	1.6230407523511	0.0548934163084996	0.246346243714284
GO:0005154	epidermal growth factor receptor binding	10/3132	35/18639	0.285714285714286	1.70032840722496	0.0574889880500949	0.256196570439273
GO:0140566	histone reader activity	10/3132	35/18639	0.285714285714286	1.70032840722496	0.0574889880500949	0.256196570439273
GO:0051287	NAD binding	14/3132	54/18639	0.259259259259259	1.54289059174117	0.0589571875992083	0.261827232428428
GO:0016410	N-acyltransferase activity	22/3132	94/18639	0.234042553191489	1.39282220591832	0.0616944715608364	0.273035394900726
GO:0003678	DNA helicase activity	18/3132	74/18639	0.243243243243243	1.44757688723206	0.0621192950734692	0.273415762041208
GO:0004860	protein kinase inhibitor activity	20/3132	84/18639	0.238095238095238	1.41694033935413	0.0622079646239183	0.273415762041208
GO:0046972	histone H4K16 acetyltransferase activity	7/3132	22/18639	0.318181818181818	1.89354754440961	0.0626883540604906	0.274583578230711
GO:0051539	4 iron, 4 sulfur cluster binding	12/3132	45/18639	0.266666666666667	1.58697318007663	0.0638500238754505	0.277769321553405
GO:0140303	intramembrane lipid transporter activity	12/3132	45/18639	0.266666666666667	1.58697318007663	0.0638500238754505	0.277769321553405
GO:0004674	protein serine/threonine kinase activity	85/3132	433/18639	0.196304849884527	1.16823949457142	0.0654851976710432	0.283917179055133
GO:0003746	translation elongation factor activity	6/3132	18/18639	0.333333333333333	1.98371647509579	0.0673920602716369	0.291197449619674
GO:0120013	lipid transfer activity	16/3132	65/18639	0.246153846153846	1.46489832007073	0.0689866099797537	0.292981327093019
GO:0042578	phosphoric ester hydrolase activity	72/3132	363/18639	0.198347107438017	1.18039327443716	0.0704488119762919	0.292981327093019
GO:0046030	inositol trisphosphate phosphatase activity	5/3132	14/18639	0.357142857142857	2.1254105090312	0.0709673331608111	0.292981327093019
GO:0098847	sequence-specific single stranded DNA binding	5/3132	14/18639	0.357142857142857	2.1254105090312	0.0709673331608111	0.292981327093019
GO:0008140	cAMP response element binding protein binding	4/3132	10/18639	0.4	2.38045977011494	0.0714700344433323	0.292981327093019
GO:0015279	store-operated calcium channel activity	4/3132	10/18639	0.4	2.38045977011494	0.0714700344433323	0.292981327093019
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	4/3132	10/18639	0.4	2.38045977011494	0.0714700344433323	0.292981327093019
GO:0030957	Tat protein binding	4/3132	10/18639	0.4	2.38045977011494	0.0714700344433323	0.292981327093019
GO:0031996	thioesterase binding	4/3132	10/18639	0.4	2.38045977011494	0.0714700344433323	0.292981327093019
GO:0043422	protein kinase B binding	4/3132	10/18639	0.4	2.38045977011494	0.0714700344433323	0.292981327093019
GO:0047429	nucleoside triphosphate diphosphatase activity	4/3132	10/18639	0.4	2.38045977011494	0.0714700344433323	0.292981327093019
GO:0050815	phosphoserine residue binding	4/3132	10/18639	0.4	2.38045977011494	0.0714700344433323	0.292981327093019
GO:0051880	G-quadruplex DNA binding	4/3132	10/18639	0.4	2.38045977011494	0.0714700344433323	0.292981327093019
GO:0097177	mitochondrial ribosome binding	4/3132	10/18639	0.4	2.38045977011494	0.0714700344433323	0.292981327093019
GO:0098505	G-rich strand telomeric DNA binding	4/3132	10/18639	0.4	2.38045977011494	0.0714700344433323	0.292981327093019
GO:1905394	retromer complex binding	4/3132	10/18639	0.4	2.38045977011494	0.0714700344433323	0.292981327093019
GO:0016849	phosphorus-oxygen lyase activity	7/3132	23/18639	0.304347826086957	1.81121939030485	0.0775447303646229	0.316868083502724
GO:0019903	protein phosphatase binding	31/3132	144/18639	0.215277777777778	1.28115022349936	0.0822904730415343	0.335189538280645
GO:0035198	miRNA binding	11/3132	42/18639	0.261904761904762	1.55863437328955	0.0826129300024598	0.335434722136972
GO:0046966	nuclear thyroid hormone receptor binding	8/3132	28/18639	0.285714285714286	1.70032840722496	0.0845830590435724	0.338781502560216
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	8/3132	28/18639	0.285714285714286	1.70032840722496	0.0845830590435724	0.338781502560216
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	6/3132	19/18639	0.315789473684211	1.87931034482759	0.0850264756230096	0.338781502560216
GO:0070003	threonine-type peptidase activity	6/3132	19/18639	0.315789473684211	1.87931034482759	0.0850264756230096	0.338781502560216
GO:0120227	acyl-CoA binding	6/3132	19/18639	0.315789473684211	1.87931034482759	0.0850264756230096	0.338781502560216
GO:0140036	ubiquitin-modified protein reader activity	6/3132	19/18639	0.315789473684211	1.87931034482759	0.0850264756230096	0.338781502560216
GO:0016504	peptidase activator activity	14/3132	57/18639	0.245614035087719	1.46168582375479	0.0863854366008024	0.343127246622442
GO:0055105	ubiquitin-protein transferase inhibitor activity	5/3132	15/18639	0.333333333333333	1.98371647509579	0.0922624933561755	0.364209040131322
GO:0140776	protein-containing complex destabilizing activity	5/3132	15/18639	0.333333333333333	1.98371647509579	0.0922624933561755	0.364209040131322
GO:0043531	ADP binding	10/3132	38/18639	0.263157894736842	1.56609195402299	0.0927519211867051	0.365014483685526
GO:0048027	mRNA 5'-UTR binding	7/3132	24/18639	0.291666666666667	1.73575191570881	0.0942704529641837	0.36985248264169
GO:0008200	ion channel inhibitor activity	11/3132	43/18639	0.255813953488372	1.52238706228281	0.0949161937133662	0.371247130762677
GO:0032934	sterol binding	16/3132	68/18639	0.235294117647059	1.40027045300879	0.096331700798712	0.373605986479041
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	4/3132	11/18639	0.363636363636364	2.16405433646813	0.0978561418846589	0.373605986479041
GO:0002162	dystroglycan binding	4/3132	11/18639	0.363636363636364	2.16405433646813	0.0978561418846589	0.373605986479041
GO:0004016	adenylate cyclase activity	4/3132	11/18639	0.363636363636364	2.16405433646813	0.0978561418846589	0.373605986479041
GO:0034056	estrogen response element binding	4/3132	11/18639	0.363636363636364	2.16405433646813	0.0978561418846589	0.373605986479041
GO:0034713	type I transforming growth factor beta receptor binding	4/3132	11/18639	0.363636363636364	2.16405433646813	0.0978561418846589	0.373605986479041
GO:0043522	leucine zipper domain binding	4/3132	11/18639	0.363636363636364	2.16405433646813	0.0978561418846589	0.373605986479041
GO:0048407	platelet-derived growth factor binding	4/3132	11/18639	0.363636363636364	2.16405433646813	0.0978561418846589	0.373605986479041
GO:0030332	cyclin binding	9/3132	34/18639	0.264705882352941	1.57530425963489	0.104354311256619	0.397229655051237
GO:0031418	L-ascorbic acid binding	6/3132	20/18639	0.3	1.78534482758621	0.104941026020544	0.398277662552746
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	46/3132	229/18639	0.200873362445415	1.19542739547257	0.107643410948845	0.407015277042127
GO:0016248	channel inhibitor activity	11/3132	44/18639	0.25	1.48778735632184	0.108257119514988	0.407015277042127
GO:0031593	polyubiquitin modification-dependent protein binding	14/3132	59/18639	0.23728813559322	1.4121371517631	0.108516191924445	0.407015277042127
GO:0070888	E-box binding	14/3132	59/18639	0.23728813559322	1.4121371517631	0.108516191924445	0.407015277042127
GO:0019210	kinase inhibitor activity	20/3132	90/18639	0.222222222222222	1.32247765006386	0.11046817852842	0.413125147186694
GO:0017056	structural constituent of nuclear pore	7/3132	25/18639	0.28	1.66632183908046	0.112827633952075	0.420718786660945
GO:0015631	tubulin binding	74/3132	385/18639	0.192207792207792	1.14385729213315	0.113737804493108	0.422155434836232
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	26/3132	122/18639	0.213114754098361	1.26827774637272	0.114203112160544	0.422155434836232
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	26/3132	122/18639	0.213114754098361	1.26827774637272	0.114203112160544	0.422155434836232
GO:0000062	fatty-acyl-CoA binding	5/3132	16/18639	0.3125	1.8597341954023	0.116425677044932	0.424240572479965
GO:0003688	DNA replication origin binding	5/3132	16/18639	0.3125	1.8597341954023	0.116425677044932	0.424240572479965
GO:0005159	insulin-like growth factor receptor binding	5/3132	16/18639	0.3125	1.8597341954023	0.116425677044932	0.424240572479965
GO:0008142	oxysterol binding	5/3132	16/18639	0.3125	1.8597341954023	0.116425677044932	0.424240572479965
GO:0034450	ubiquitin-ubiquitin ligase activity	5/3132	16/18639	0.3125	1.8597341954023	0.116425677044932	0.424240572479965
GO:0015215	nucleotide transmembrane transporter activity	8/3132	30/18639	0.266666666666667	1.58697318007663	0.117699354743977	0.426451769738092
GO:0051721	protein phosphatase 2A binding	8/3132	30/18639	0.266666666666667	1.58697318007663	0.117699354743977	0.426451769738092
GO:0030331	nuclear estrogen receptor binding	10/3132	40/18639	0.25	1.48778735632184	0.122084621800326	0.439518488863375
GO:0032813	tumor necrosis factor receptor superfamily binding	12/3132	50/18639	0.24	1.42827586206897	0.122464614528254	0.439518488863375
GO:0141110	transporter inhibitor activity	11/3132	45/18639	0.244444444444444	1.45472541507024	0.122624121045427	0.439518488863375
GO:0016209	antioxidant activity	19/3132	86/18639	0.22093023255814	1.31478882651697	0.122680297516986	0.439518488863375
GO:0022853	active monoatomic ion transmembrane transporter activity	25/3132	118/18639	0.211864406779661	1.26083674264563	0.125681349043394	0.442619651757689
GO:0005123	death receptor binding	6/3132	21/18639	0.285714285714286	1.70032840722496	0.127035741405115	0.442619651757689
GO:0009975	cyclase activity	6/3132	21/18639	0.285714285714286	1.70032840722496	0.127035741405115	0.442619651757689
GO:0000995	RNA polymerase III general transcription initiation factor activity	4/3132	12/18639	0.333333333333333	1.98371647509579	0.128044778069073	0.442619651757689
GO:0008179	adenylate cyclase binding	4/3132	12/18639	0.333333333333333	1.98371647509579	0.128044778069073	0.442619651757689
GO:0010853	cyclase activator activity	4/3132	12/18639	0.333333333333333	1.98371647509579	0.128044778069073	0.442619651757689
GO:0035197	siRNA binding	4/3132	12/18639	0.333333333333333	1.98371647509579	0.128044778069073	0.442619651757689
GO:0035251	UDP-glucosyltransferase activity	4/3132	12/18639	0.333333333333333	1.98371647509579	0.128044778069073	0.442619651757689
GO:0035259	nuclear glucocorticoid receptor binding	4/3132	12/18639	0.333333333333333	1.98371647509579	0.128044778069073	0.442619651757689
GO:0035497	cAMP response element binding	4/3132	12/18639	0.333333333333333	1.98371647509579	0.128044778069073	0.442619651757689
GO:0070679	inositol 1,4,5 trisphosphate binding	4/3132	12/18639	0.333333333333333	1.98371647509579	0.128044778069073	0.442619651757689
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/3132	12/18639	0.333333333333333	1.98371647509579	0.128044778069073	0.442619651757689
GO:1990459	transferrin receptor binding	4/3132	12/18639	0.333333333333333	1.98371647509579	0.128044778069073	0.442619651757689
GO:0005112	Notch binding	7/3132	26/18639	0.269230769230769	1.60223253757737	0.133145686600721	0.457777777318072
GO:0052742	phosphatidylinositol kinase activity	7/3132	26/18639	0.269230769230769	1.60223253757737	0.133145686600721	0.457777777318072
GO:0044325	transmembrane transporter binding	28/3132	136/18639	0.205882352941176	1.22523664638269	0.142899118057198	0.483366094746563
GO:0004659	prenyltransferase activity	5/3132	17/18639	0.294117647058824	1.75033806626099	0.143233580851405	0.483366094746563
GO:0008484	sulfuric ester hydrolase activity	5/3132	17/18639	0.294117647058824	1.75033806626099	0.143233580851405	0.483366094746563
GO:0017110	nucleoside diphosphate phosphatase activity	5/3132	17/18639	0.294117647058824	1.75033806626099	0.143233580851405	0.483366094746563
GO:0032977	membrane insertase activity	5/3132	17/18639	0.294117647058824	1.75033806626099	0.143233580851405	0.483366094746563
GO:0048038	quinone binding	5/3132	17/18639	0.294117647058824	1.75033806626099	0.143233580851405	0.483366094746563
GO:1901567	fatty acid derivative binding	5/3132	17/18639	0.294117647058824	1.75033806626099	0.143233580851405	0.483366094746563
GO:0016651	oxidoreductase activity, acting on NAD(P)H	19/3132	88/18639	0.215909090909091	1.28490726227795	0.144785545001484	0.487317663307626
GO:0140035	ubiquitin-like protein reader activity	6/3132	22/18639	0.272727272727273	1.6230407523511	0.151166011659349	0.507457556200281
GO:0005080	protein kinase C binding	12/3132	52/18639	0.230769230769231	1.37334217506631	0.152325570556121	0.51001153073633
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	7/3132	27/18639	0.259259259259259	1.54289059174117	0.155124507814331	0.518026750638457
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	27/3132	132/18639	0.204545454545455	1.21728056426332	0.156334755191503	0.520605685045854
GO:0120015	sterol transfer activity	8/3132	32/18639	0.25	1.48778735632184	0.156710859063842	0.520605685045854
GO:0031432	titin binding	4/3132	13/18639	0.307692307692308	1.83112290008842	0.161536925469602	0.53386492939437
GO:0046975	histone H3K36 methyltransferase activity	4/3132	13/18639	0.307692307692308	1.83112290008842	0.161536925469602	0.53386492939437
GO:0005096	GTPase activator activity	52/3132	271/18639	0.191881918819188	1.14191797090385	0.164263246978356	0.541476012591026
GO:0005543	phospholipid binding	92/3132	497/18639	0.185110663983903	1.10162122158237	0.165493460617461	0.544128884652268
GO:0032266	phosphatidylinositol-3-phosphate binding	11/3132	48/18639	0.229166666666667	1.36380507662835	0.17161610886995	0.558237833091321
GO:0140101	catalytic activity, acting on a tRNA	28/3132	139/18639	0.201438848920863	1.19879268998594	0.171866587414875	0.558237833091321
GO:0000900	mRNA regulatory element binding translation repressor activity	5/3132	18/18639	0.277777777777778	1.65309706257982	0.172403396459009	0.558237833091321
GO:0008308	voltage-gated monoatomic anion channel activity	5/3132	18/18639	0.277777777777778	1.65309706257982	0.172403396459009	0.558237833091321
GO:0008409	5'-3' exonuclease activity	5/3132	18/18639	0.277777777777778	1.65309706257982	0.172403396459009	0.558237833091321
GO:0031690	adrenergic receptor binding	5/3132	18/18639	0.277777777777778	1.65309706257982	0.172403396459009	0.558237833091321
GO:0016279	protein-lysine N-methyltransferase activity	15/3132	69/18639	0.217391304347826	1.29372813593203	0.172861766789816	0.558308585162056
GO:0004712	protein serine/threonine/tyrosine kinase activity	10/3132	43/18639	0.232558139534884	1.38398823843892	0.174380593523413	0.561795413391548
GO:0042171	lysophosphatidic acid acyltransferase activity	6/3132	23/18639	0.260869565217391	1.55247376311844	0.177149993292781	0.565540634869131
GO:0071617	lysophospholipid acyltransferase activity	6/3132	23/18639	0.260869565217391	1.55247376311844	0.177149993292781	0.565540634869131
GO:0000049	tRNA binding	17/3132	80/18639	0.2125	1.26461925287356	0.17814832467017	0.565540634869131
GO:0140311	protein sequestering activity	8/3132	33/18639	0.242424242424242	1.44270289097875	0.178235497182623	0.565540634869131
GO:0046625	sphingolipid binding	7/3132	28/18639	0.25	1.48778735632184	0.17863832407125	0.565540634869131
GO:0051019	mitogen-activated protein kinase binding	7/3132	28/18639	0.25	1.48778735632184	0.17863832407125	0.565540634869131
GO:0141052	histone H3 demethylase activity	7/3132	28/18639	0.25	1.48778735632184	0.17863832407125	0.565540634869131
GO:0004879	nuclear receptor activity	13/3132	59/18639	0.220338983050847	1.31127021235145	0.181338451126383	0.572671306149738
GO:0015485	cholesterol binding	12/3132	54/18639	0.222222222222222	1.32247765006386	0.185585741304028	0.584640795881408
GO:0016278	lysine N-methyltransferase activity	15/3132	70/18639	0.214285714285714	1.27524630541872	0.187862407415652	0.590358769249677
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	9/3132	39/18639	0.230769230769231	1.37334217506631	0.197624101895712	0.606146594077547
GO:0140034	methylation-dependent protein binding	16/3132	76/18639	0.210526315789474	1.25287356321839	0.197756828393167	0.606146594077547
GO:0004065	arylsulfatase activity	4/3132	14/18639	0.285714285714286	1.70032840722496	0.197764762393119	0.606146594077547
GO:0005347	ATP transmembrane transporter activity	4/3132	14/18639	0.285714285714286	1.70032840722496	0.197764762393119	0.606146594077547
GO:0008474	palmitoyl-(protein) hydrolase activity	4/3132	14/18639	0.285714285714286	1.70032840722496	0.197764762393119	0.606146594077547
GO:0016530	metallochaperone activity	4/3132	14/18639	0.285714285714286	1.70032840722496	0.197764762393119	0.606146594077547
GO:0042813	Wnt receptor activity	4/3132	14/18639	0.285714285714286	1.70032840722496	0.197764762393119	0.606146594077547
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	4/3132	14/18639	0.285714285714286	1.70032840722496	0.197764762393119	0.606146594077547
GO:0098599	palmitoyl hydrolase activity	4/3132	14/18639	0.285714285714286	1.70032840722496	0.197764762393119	0.606146594077547
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	13/3132	60/18639	0.216666666666667	1.28941570881226	0.19809951237249	0.606146594077547
GO:0098531	ligand-modulated transcription factor activity	13/3132	60/18639	0.216666666666667	1.28941570881226	0.19809951237249	0.606146594077547
GO:0046624	sphingolipid transporter activity	5/3132	19/18639	0.263157894736842	1.56609195402299	0.203609439614722	0.621519029277398
GO:0140033	acetylation-dependent protein binding	6/3132	24/18639	0.25	1.48778735632184	0.204776506735647	0.623593219321173
GO:0015605	organophosphate ester transmembrane transporter activity	11/3132	50/18639	0.22	1.30925287356322	0.208760458295045	0.634215264036489
GO:0046915	transition metal ion transmembrane transporter activity	10/3132	45/18639	0.222222222222222	1.32247765006386	0.214172832133754	0.649116237675524
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	13/3132	61/18639	0.213114754098361	1.26827774637272	0.215533578176947	0.651696090988926
GO:0032451	demethylase activity	9/3132	40/18639	0.225	1.33900862068966	0.219554918697599	0.660983302782685
GO:0005518	collagen binding	15/3132	72/18639	0.208333333333333	1.23982279693487	0.219638704990337	0.660983302782685
GO:0019212	phosphatase inhibitor activity	12/3132	56/18639	0.214285714285714	1.27524630541872	0.221905863660427	0.661886448423519
GO:0042054	histone methyltransferase activity	14/3132	67/18639	0.208955223880597	1.24352376050781	0.226454959919049	0.661886448423519
GO:0001094	TFIID-class transcription factor complex binding	3/3132	10/18639	0.3	1.78534482758621	0.228563928826353	0.661886448423519
GO:0004090	carbonyl reductase (NADPH) activity	3/3132	10/18639	0.3	1.78534482758621	0.228563928826353	0.661886448423519
GO:0005381	iron ion transmembrane transporter activity	3/3132	10/18639	0.3	1.78534482758621	0.228563928826353	0.661886448423519
GO:0005522	profilin binding	3/3132	10/18639	0.3	1.78534482758621	0.228563928826353	0.661886448423519
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/3132	10/18639	0.3	1.78534482758621	0.228563928826353	0.661886448423519
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/3132	10/18639	0.3	1.78534482758621	0.228563928826353	0.661886448423519
GO:0016427	tRNA (cytidine) methyltransferase activity	3/3132	10/18639	0.3	1.78534482758621	0.228563928826353	0.661886448423519
GO:0031434	mitogen-activated protein kinase kinase binding	3/3132	10/18639	0.3	1.78534482758621	0.228563928826353	0.661886448423519
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	3/3132	10/18639	0.3	1.78534482758621	0.228563928826353	0.661886448423519
GO:0070513	death domain binding	3/3132	10/18639	0.3	1.78534482758621	0.228563928826353	0.661886448423519
GO:0099122	RNA polymerase II C-terminal domain binding	3/3132	10/18639	0.3	1.78534482758621	0.228563928826353	0.661886448423519
GO:0032452	histone demethylase activity	7/3132	30/18639	0.233333333333333	1.38860153256705	0.229665371862591	0.661886448423519
GO:1902936	phosphatidylinositol bisphosphate binding	22/3132	111/18639	0.198198198198198	1.1795070933002	0.230122575128414	0.661886448423519
GO:0005319	lipid transporter activity	34/3132	178/18639	0.191011235955056	1.13673640707736	0.23161352782194	0.661886448423519
GO:0070851	growth factor receptor binding	27/3132	139/18639	0.194244604316547	1.15597866534359	0.233357547333317	0.661886448423519
GO:0000030	mannosyltransferase activity	6/3132	25/18639	0.24	1.42827586206897	0.233812992877828	0.661886448423519
GO:0004709	MAP kinase kinase kinase activity	6/3132	25/18639	0.24	1.42827586206897	0.233812992877828	0.661886448423519
GO:0030276	clathrin binding	10/3132	46/18639	0.217391304347826	1.29372813593203	0.235333207313899	0.661886448423519
GO:0004129	cytochrome-c oxidase activity	4/3132	15/18639	0.266666666666667	1.58697318007663	0.236129223861098	0.661886448423519
GO:0004559	alpha-mannosidase activity	4/3132	15/18639	0.266666666666667	1.58697318007663	0.236129223861098	0.661886448423519
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	4/3132	15/18639	0.266666666666667	1.58697318007663	0.236129223861098	0.661886448423519
GO:0031386	protein tag activity	4/3132	15/18639	0.266666666666667	1.58697318007663	0.236129223861098	0.661886448423519
GO:0042809	nuclear vitamin D receptor binding	4/3132	15/18639	0.266666666666667	1.58697318007663	0.236129223861098	0.661886448423519
GO:0050780	dopamine receptor binding	4/3132	15/18639	0.266666666666667	1.58697318007663	0.236129223861098	0.661886448423519
GO:0141047	molecular tag activity	4/3132	15/18639	0.266666666666667	1.58697318007663	0.236129223861098	0.661886448423519
GO:0141050	histone H3K deacetylase activity	4/3132	15/18639	0.266666666666667	1.58697318007663	0.236129223861098	0.661886448423519
GO:0141051	histone H4K deacetylase activity	4/3132	15/18639	0.266666666666667	1.58697318007663	0.236129223861098	0.661886448423519
GO:0010851	cyclase regulator activity	5/3132	20/18639	0.25	1.48778735632184	0.236498910812782	0.661886448423519
GO:0015095	magnesium ion transmembrane transporter activity	5/3132	20/18639	0.25	1.48778735632184	0.236498910812782	0.661886448423519
GO:0016505	peptidase activator activity involved in apoptotic process	5/3132	20/18639	0.25	1.48778735632184	0.236498910812782	0.661886448423519
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	9/3132	41/18639	0.219512195121951	1.30634987384357	0.242365373616277	0.675349265479779
GO:0016877	ligase activity, forming carbon-sulfur bonds	9/3132	41/18639	0.219512195121951	1.30634987384357	0.242365373616277	0.675349265479779
GO:0005507	copper ion binding	13/3132	63/18639	0.206349206349206	1.22801496077358	0.252227810190953	0.70130297659615
GO:0035064	methylated histone binding	15/3132	74/18639	0.202702702702703	1.20631407269338	0.253545342333971	0.701914486677811
GO:0048029	monosaccharide binding	15/3132	74/18639	0.202702702702703	1.20631407269338	0.253545342333971	0.701914486677811
GO:0005164	tumor necrosis factor receptor binding	7/3132	31/18639	0.225806451612903	1.34380793474231	0.25683809443288	0.707502476289623
GO:0140457	protein demethylase activity	7/3132	31/18639	0.225806451612903	1.34380793474231	0.25683809443288	0.707502476289623
GO:1990518	single-stranded 3'-5' DNA helicase activity	10/3132	47/18639	0.212765957446809	1.26620200538029	0.257223339698729	0.707502476289623
GO:0004112	cyclic-nucleotide phosphodiesterase activity	6/3132	26/18639	0.230769230769231	1.37334217506631	0.26401318476096	0.71722017632488
GO:0004529	DNA exonuclease activity	6/3132	26/18639	0.230769230769231	1.37334217506631	0.26401318476096	0.71722017632488
GO:0005160	transforming growth factor beta receptor binding	6/3132	26/18639	0.230769230769231	1.37334217506631	0.26401318476096	0.71722017632488
GO:0008198	ferrous iron binding	6/3132	26/18639	0.230769230769231	1.37334217506631	0.26401318476096	0.71722017632488
GO:0070006	metalloaminopeptidase activity	6/3132	26/18639	0.230769230769231	1.37334217506631	0.26401318476096	0.71722017632488
GO:0004864	protein phosphatase inhibitor activity	11/3132	53/18639	0.207547169811321	1.23514422034266	0.270002833106671	0.71722017632488
GO:0005246	calcium channel regulator activity	11/3132	53/18639	0.207547169811321	1.23514422034266	0.270002833106671	0.71722017632488
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	5/3132	21/18639	0.238095238095238	1.41694033935413	0.270706151252678	0.71722017632488
GO:0035613	RNA stem-loop binding	5/3132	21/18639	0.238095238095238	1.41694033935413	0.270706151252678	0.71722017632488
GO:0070182	DNA polymerase binding	5/3132	21/18639	0.238095238095238	1.41694033935413	0.270706151252678	0.71722017632488
GO:0140312	cargo adaptor activity	5/3132	21/18639	0.238095238095238	1.41694033935413	0.270706151252678	0.71722017632488
GO:0004536	DNA nuclease activity	13/3132	64/18639	0.203125	1.20882722701149	0.271381729760767	0.71722017632488
GO:0008296	3'-5'-DNA exonuclease activity	4/3132	16/18639	0.25	1.48778735632184	0.276030406133153	0.71722017632488
GO:0015923	mannosidase activity	4/3132	16/18639	0.25	1.48778735632184	0.276030406133153	0.71722017632488
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/3132	16/18639	0.25	1.48778735632184	0.276030406133153	0.71722017632488
GO:0016722	oxidoreductase activity, acting on metal ions	4/3132	16/18639	0.25	1.48778735632184	0.276030406133153	0.71722017632488
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/3132	16/18639	0.25	1.48778735632184	0.276030406133153	0.71722017632488
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	4/3132	16/18639	0.25	1.48778735632184	0.276030406133153	0.71722017632488
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/3132	11/18639	0.272727272727273	1.6230407523511	0.277579348929488	0.71722017632488
GO:0008432	JUN kinase binding	3/3132	11/18639	0.272727272727273	1.6230407523511	0.277579348929488	0.71722017632488
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	3/3132	11/18639	0.272727272727273	1.6230407523511	0.277579348929488	0.71722017632488
GO:0015217	ADP transmembrane transporter activity	3/3132	11/18639	0.272727272727273	1.6230407523511	0.277579348929488	0.71722017632488
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	3/3132	11/18639	0.272727272727273	1.6230407523511	0.277579348929488	0.71722017632488
GO:0032050	clathrin heavy chain binding	3/3132	11/18639	0.272727272727273	1.6230407523511	0.277579348929488	0.71722017632488
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	3/3132	11/18639	0.272727272727273	1.6230407523511	0.277579348929488	0.71722017632488
GO:0045294	alpha-catenin binding	3/3132	11/18639	0.272727272727273	1.6230407523511	0.277579348929488	0.71722017632488
GO:0070697	activin receptor binding	3/3132	11/18639	0.272727272727273	1.6230407523511	0.277579348929488	0.71722017632488
GO:0097493	structural molecule activity conferring elasticity	3/3132	11/18639	0.272727272727273	1.6230407523511	0.277579348929488	0.71722017632488
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/3132	11/18639	0.272727272727273	1.6230407523511	0.277579348929488	0.71722017632488
GO:1990948	ubiquitin ligase inhibitor activity	3/3132	11/18639	0.272727272727273	1.6230407523511	0.277579348929488	0.71722017632488
GO:0036121	double-stranded DNA helicase activity	10/3132	48/18639	0.208333333333333	1.23982279693487	0.279751558337882	0.719924030410766
GO:0043138	3'-5' DNA helicase activity	10/3132	48/18639	0.208333333333333	1.23982279693487	0.279751558337882	0.719924030410766
GO:0097110	scaffold protein binding	14/3132	70/18639	0.2	1.19022988505747	0.280786517001292	0.720629916828699
GO:0045309	protein phosphorylated amino acid binding	12/3132	59/18639	0.203389830508475	1.2104032729398	0.281152719700955	0.720629916828699
GO:0016829	lyase activity	37/3132	200/18639	0.185	1.10096264367816	0.286273113965344	0.731603478525085
GO:0017124	SH3 domain binding	22/3132	115/18639	0.191304347826087	1.13848075962019	0.286578063128278	0.731603478525085
GO:0015399	primary active transmembrane transporter activity	31/3132	166/18639	0.186746987951807	1.11135923002354	0.287997987510833	0.733763796865251
GO:0160215	deacylase activity	13/3132	65/18639	0.2	1.19022988505747	0.290997374005249	0.739931692550127
GO:0050661	NADP binding	11/3132	54/18639	0.203703703703704	1.2122711792252	0.291597903102696	0.739987535849897
GO:0005385	zinc ion transmembrane transporter activity	6/3132	27/18639	0.222222222222222	1.32247765006386	0.29512423531714	0.74597608096961
GO:0035255	ionotropic glutamate receptor binding	6/3132	27/18639	0.222222222222222	1.32247765006386	0.29512423531714	0.74597608096961
GO:0019783	ubiquitin-like protein peptidase activity	24/3132	127/18639	0.188976377952756	1.12462666304643	0.296952396119928	0.749116596917925
GO:0060589	nucleoside-triphosphatase regulator activity	87/3132	490/18639	0.177551020408163	1.05663265306122	0.301826583788197	0.756675735508739
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	12/3132	60/18639	0.2	1.19022988505747	0.301916021533071	0.756675735508739
GO:0004197	cysteine-type endopeptidase activity	17/3132	88/18639	0.193181818181818	1.14965386624869	0.303954063280969	0.756675735508739
GO:0004407	histone deacetylase activity	5/3132	22/18639	0.227272727272727	1.35253396029258	0.305865015838951	0.756675735508739
GO:0008649	rRNA methyltransferase activity	5/3132	22/18639	0.227272727272727	1.35253396029258	0.305865015838951	0.756675735508739
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	5/3132	22/18639	0.227272727272727	1.35253396029258	0.305865015838951	0.756675735508739
GO:0033558	protein lysine deacetylase activity	5/3132	22/18639	0.227272727272727	1.35253396029258	0.305865015838951	0.756675735508739
GO:0034062	5'-3' RNA polymerase activity	5/3132	22/18639	0.227272727272727	1.35253396029258	0.305865015838951	0.756675735508739
GO:0050321	tau-protein kinase activity	5/3132	22/18639	0.227272727272727	1.35253396029258	0.305865015838951	0.756675735508739
GO:0097747	RNA polymerase activity	5/3132	22/18639	0.227272727272727	1.35253396029258	0.305865015838951	0.756675735508739
GO:0046982	protein heterodimerization activity	66/3132	369/18639	0.178861788617886	1.0644332305392	0.307565624281498	0.759413964200841
GO:0004679	AMP-activated protein kinase activity	45/3132	248/18639	0.181451612903226	1.0798456618465	0.309458472285938	0.762615387386734
GO:0140313	molecular sequestering activity	11/3132	55/18639	0.2	1.19022988505747	0.313650258094014	0.770114479086479
GO:0016790	thiolester hydrolase activity	9/3132	44/18639	0.204545454545455	1.21728056426332	0.314962077372207	0.770114479086479
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/3132	17/18639	0.235294117647059	1.40027045300879	0.316890967758307	0.770114479086479
GO:0016018	cyclosporin A binding	4/3132	17/18639	0.235294117647059	1.40027045300879	0.316890967758307	0.770114479086479
GO:0031489	myosin V binding	4/3132	17/18639	0.235294117647059	1.40027045300879	0.316890967758307	0.770114479086479
GO:0032183	SUMO binding	4/3132	17/18639	0.235294117647059	1.40027045300879	0.316890967758307	0.770114479086479
GO:0070403	NAD+ binding	4/3132	17/18639	0.235294117647059	1.40027045300879	0.316890967758307	0.770114479086479
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	44/3132	243/18639	0.181069958847737	1.07757438153351	0.317318475745562	0.770114479086479
GO:0000149	SNARE binding	20/3132	106/18639	0.188679245283019	1.12285838212969	0.321840357359957	0.77737582019017
GO:0004000	adenosine deaminase activity	3/3132	12/18639	0.25	1.48778735632184	0.327424205882959	0.77737582019017
GO:0004300	enoyl-CoA hydratase activity	3/3132	12/18639	0.25	1.48778735632184	0.327424205882959	0.77737582019017
GO:0005078	MAP-kinase scaffold activity	3/3132	12/18639	0.25	1.48778735632184	0.327424205882959	0.77737582019017
GO:0005165	neurotrophin receptor binding	3/3132	12/18639	0.25	1.48778735632184	0.327424205882959	0.77737582019017
GO:0031543	peptidyl-proline dioxygenase activity	3/3132	12/18639	0.25	1.48778735632184	0.327424205882959	0.77737582019017
GO:0034452	dynactin binding	3/3132	12/18639	0.25	1.48778735632184	0.327424205882959	0.77737582019017
GO:0070008	serine-type exopeptidase activity	3/3132	12/18639	0.25	1.48778735632184	0.327424205882959	0.77737582019017
GO:0097677	STAT family protein binding	3/3132	12/18639	0.25	1.48778735632184	0.327424205882959	0.77737582019017
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	3/3132	12/18639	0.25	1.48778735632184	0.327424205882959	0.77737582019017
GO:0141221	histone deacetylase activity, hydrolytic mechanism	3/3132	12/18639	0.25	1.48778735632184	0.327424205882959	0.77737582019017
GO:0016776	phosphotransferase activity, phosphate group as acceptor	8/3132	39/18639	0.205128205128205	1.22074860005894	0.328198107182233	0.77737582019017
GO:0030695	GTPase regulator activity	86/3132	489/18639	0.175869120654397	1.04662341630821	0.337646179492435	0.77737582019017
GO:0004676	3-phosphoinositide-dependent protein kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0004711	ribosomal protein S6 kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0035175	histone H3S10 kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0035979	histone H2AXS139 kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0044022	histone H3S28 kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0044023	histone H4S1 kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0044024	histone H2AS1 kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0044025	histone H2BS14 kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0072354	histone H3T3 kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0072371	histone H2AS121 kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0072518	Rho-dependent protein serine/threonine kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0140823	histone H2BS36 kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0140855	histone H3S57 kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0140995	histone H2A kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0140997	histone H4 kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0140998	histone H2B kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:1990244	histone H2AT120 kinase activity	44/3132	245/18639	0.179591836734694	1.06877785596997	0.338544434594155	0.77737582019017
GO:0004715	non-membrane spanning protein tyrosine kinase activity	9/3132	45/18639	0.2	1.19022988505747	0.34015938868182	0.778714971804765
GO:0031681	G-protein beta-subunit binding	5/3132	23/18639	0.217391304347826	1.29372813593203	0.341619188768443	0.778714971804765
GO:0070577	lysine-acetylated histone binding	5/3132	23/18639	0.217391304347826	1.29372813593203	0.341619188768443	0.778714971804765
GO:0140102	catalytic activity, acting on a rRNA	5/3132	23/18639	0.217391304347826	1.29372813593203	0.341619188768443	0.778714971804765
GO:0016831	carboxy-lyase activity	7/3132	34/18639	0.205882352941176	1.22523664638269	0.342780710810073	0.778714971804765
GO:0052866	phosphatidylinositol phosphate phosphatase activity	7/3132	34/18639	0.205882352941176	1.22523664638269	0.342780710810073	0.778714971804765
GO:0002020	protease binding	25/3132	136/18639	0.183823529411765	1.09396129141312	0.3444118093352	0.7810331633683
GO:0004677	DNA-dependent protein kinase activity	44/3132	246/18639	0.178861788617886	1.0644332305392	0.349309683149476	0.789341139131059
GO:0140857	histone H3T45 kinase activity	44/3132	246/18639	0.178861788617886	1.0644332305392	0.349309683149476	0.789341139131059
GO:0016830	carbon-carbon lyase activity	10/3132	51/18639	0.196078431372549	1.16689204417399	0.35019893124055	0.789954908389176
GO:0005496	steroid binding	20/3132	108/18639	0.185185185185185	1.10206470838655	0.354356461528408	0.797925905448652
GO:0004706	JUN kinase kinase kinase activity	4/3132	18/18639	0.222222222222222	1.32247765006386	0.358173130986677	0.799741457325376
GO:0008525	phosphatidylcholine transporter activity	4/3132	18/18639	0.222222222222222	1.32247765006386	0.358173130986677	0.799741457325376
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	4/3132	18/18639	0.222222222222222	1.32247765006386	0.358173130986677	0.799741457325376
GO:1901611	phosphatidylglycerol binding	4/3132	18/18639	0.222222222222222	1.32247765006386	0.358173130986677	0.799741457325376
GO:0015932	nucleobase-containing compound transmembrane transporter activity	11/3132	57/18639	0.192982456140351	1.14846743295019	0.358793078167663	0.799741457325376
GO:0051861	glycolipid binding	6/3132	29/18639	0.206896551724138	1.23127229488704	0.359072203419984	0.799741457325376
GO:0035402	histone H3T11 kinase activity	44/3132	247/18639	0.178137651821862	1.06012378426172	0.360165034729802	0.799741457325376
GO:0035403	histone H3T6 kinase activity	44/3132	247/18639	0.178137651821862	1.06012378426172	0.360165034729802	0.799741457325376
GO:0016229	steroid dehydrogenase activity	7/3132	35/18639	0.2	1.19022988505747	0.372278938910304	0.818625946285604
GO:0043015	gamma-tubulin binding	7/3132	35/18639	0.2	1.19022988505747	0.372278938910304	0.818625946285604
GO:0035401	histone H3Y41 kinase activity	21/3132	115/18639	0.182608695652174	1.08673163418291	0.374863788981548	0.818625946285604
GO:0140801	histone H2AXY142 kinase activity	21/3132	115/18639	0.182608695652174	1.08673163418291	0.374863788981548	0.818625946285604
GO:0043178	alcohol binding	17/3132	92/18639	0.184782608695652	1.09966891554223	0.374950720455985	0.818625946285604
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	3/3132	13/18639	0.230769230769231	1.37334217506631	0.377190390006967	0.818625946285604
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/3132	13/18639	0.230769230769231	1.37334217506631	0.377190390006967	0.818625946285604
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/3132	13/18639	0.230769230769231	1.37334217506631	0.377190390006967	0.818625946285604
GO:0008035	high-density lipoprotein particle binding	3/3132	13/18639	0.230769230769231	1.37334217506631	0.377190390006967	0.818625946285604
GO:0019855	calcium channel inhibitor activity	3/3132	13/18639	0.230769230769231	1.37334217506631	0.377190390006967	0.818625946285604
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	5/3132	24/18639	0.208333333333333	1.23982279693487	0.377630420882335	0.818625946285604
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	5/3132	24/18639	0.208333333333333	1.23982279693487	0.377630420882335	0.818625946285604
GO:0050431	transforming growth factor beta binding	5/3132	24/18639	0.208333333333333	1.23982279693487	0.377630420882335	0.818625946285604
GO:0050699	WW domain binding	5/3132	24/18639	0.208333333333333	1.23982279693487	0.377630420882335	0.818625946285604
GO:0004725	protein tyrosine phosphatase activity	18/3132	98/18639	0.183673469387755	1.09306826178747	0.379472522058356	0.821227336231197
GO:0141003	histone H2AX kinase activity	62/3132	354/18639	0.175141242937853	1.04229170725372	0.380865519576266	0.821373961761428
GO:0017116	single-stranded DNA helicase activity	11/3132	58/18639	0.189655172413793	1.12866627031312	0.381715572252313	0.821373961761428
GO:0035173	histone kinase activity	63/3132	360/18639	0.175	1.04145114942529	0.382250718184278	0.821373961761428
GO:0015078	proton transmembrane transporter activity	33/3132	185/18639	0.178378378378378	1.06155638397018	0.382477312347203	0.821373961761428
GO:0001530	lipopolysaccharide binding	8/3132	41/18639	0.195121951219512	1.16119988786095	0.382751275379055	0.821373961761428
GO:0005201	extracellular matrix structural constituent	30/3132	168/18639	0.178571428571429	1.0627052545156	0.388160780847636	0.831587334512775
GO:0061749	forked DNA-dependent helicase activity	9/3132	47/18639	0.191489361702128	1.13958180484226	0.391339459115675	0.832996975981088
GO:0140938	histone H3 methyltransferase activity	9/3132	47/18639	0.191489361702128	1.13958180484226	0.391339459115675	0.832996975981088
GO:0008106	alcohol dehydrogenase (NADP+) activity	6/3132	30/18639	0.2	1.19022988505747	0.391423911309331	0.832996975981088
GO:0031210	phosphatidylcholine binding	6/3132	30/18639	0.2	1.19022988505747	0.391423911309331	0.832996975981088
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/3132	19/18639	0.210526315789474	1.25287356321839	0.399390115352531	0.844330508323781
GO:0008301	DNA binding, bending	4/3132	19/18639	0.210526315789474	1.25287356321839	0.399390115352531	0.844330508323781
GO:0046527	glucosyltransferase activity	4/3132	19/18639	0.210526315789474	1.25287356321839	0.399390115352531	0.844330508323781
GO:0050145	nucleoside monophosphate kinase activity	4/3132	19/18639	0.210526315789474	1.25287356321839	0.399390115352531	0.844330508323781
GO:0005484	SNAP receptor activity	7/3132	36/18639	0.194444444444444	1.15716794380587	0.401900131880895	0.845444520848132
GO:0016409	palmitoyltransferase activity	7/3132	36/18639	0.194444444444444	1.15716794380587	0.401900131880895	0.845444520848132
GO:0045505	dynein intermediate chain binding	7/3132	36/18639	0.194444444444444	1.15716794380587	0.401900131880895	0.845444520848132
GO:0004713	protein tyrosine kinase activity	25/3132	140/18639	0.178571428571429	1.0627052545156	0.403357776151872	0.847117562722898
GO:0001786	phosphatidylserine binding	11/3132	59/18639	0.186440677966102	1.10953633352815	0.404761225962	0.847282500827164
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	11/3132	59/18639	0.186440677966102	1.10953633352815	0.404761225962	0.847282500827164
GO:0140996	histone H3 kinase activity	62/3132	357/18639	0.173669467787115	1.03353295341125	0.408856348604887	0.854456323309886
GO:0004520	DNA endonuclease activity	8/3132	42/18639	0.19047619047619	1.13355227148331	0.410234704259797	0.855938314434389
GO:0003707	nuclear steroid receptor activity	5/3132	25/18639	0.2	1.19022988505747	0.413584777883462	0.857333761609316
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	5/3132	25/18639	0.2	1.19022988505747	0.413584777883462	0.857333761609316
GO:0047617	fatty acyl-CoA hydrolase activity	5/3132	25/18639	0.2	1.19022988505747	0.413584777883462	0.857333761609316
GO:0120020	cholesterol transfer activity	5/3132	25/18639	0.2	1.19022988505747	0.413584777883462	0.857333761609316
GO:0009378	four-way junction helicase activity	9/3132	48/18639	0.1875	1.11584051724138	0.417090513141319	0.863201887229363
GO:0016411	acylglycerol O-acyltransferase activity	6/3132	31/18639	0.193548387096774	1.15183537263626	0.423724507359679	0.869239920278722
GO:0005545	1-phosphatidylinositol binding	3/3132	14/18639	0.214285714285714	1.27524630541872	0.42612465208347	0.869239920278722
GO:0008174	mRNA methyltransferase activity	3/3132	14/18639	0.214285714285714	1.27524630541872	0.42612465208347	0.869239920278722
GO:0008191	metalloendopeptidase inhibitor activity	3/3132	14/18639	0.214285714285714	1.27524630541872	0.42612465208347	0.869239920278722
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/3132	14/18639	0.214285714285714	1.27524630541872	0.42612465208347	0.869239920278722
GO:0032454	histone H3K9 demethylase activity	3/3132	14/18639	0.214285714285714	1.27524630541872	0.42612465208347	0.869239920278722
GO:0061665	SUMO ligase activity	3/3132	14/18639	0.214285714285714	1.27524630541872	0.42612465208347	0.869239920278722
GO:0071933	Arp2/3 complex binding	3/3132	14/18639	0.214285714285714	1.27524630541872	0.42612465208347	0.869239920278722
GO:1901612	cardiolipin binding	3/3132	14/18639	0.214285714285714	1.27524630541872	0.42612465208347	0.869239920278722
GO:0019213	deacetylase activity	7/3132	37/18639	0.189189189189189	1.12589313451382	0.431474511806637	0.877354372974068
GO:0042805	actinin binding	7/3132	37/18639	0.189189189189189	1.12589313451382	0.431474511806637	0.877354372974068
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	4/3132	20/18639	0.2	1.19022988505747	0.440112916487469	0.889264486868045
GO:0016004	phospholipase activator activity	4/3132	20/18639	0.2	1.19022988505747	0.440112916487469	0.889264486868045
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	4/3132	20/18639	0.2	1.19022988505747	0.440112916487469	0.889264486868045
GO:0140939	histone H4 methyltransferase activity	4/3132	20/18639	0.2	1.19022988505747	0.440112916487469	0.889264486868045
GO:0042277	peptide binding	43/3132	249/18639	0.172690763052209	1.02770853529059	0.448031087640587	0.90192000352772
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/3132	26/18639	0.192307692307692	1.14445181255526	0.449197061960248	0.90192000352772
GO:0015216	purine nucleotide transmembrane transporter activity	5/3132	26/18639	0.192307692307692	1.14445181255526	0.449197061960248	0.90192000352772
GO:0016289	acyl-CoA hydrolase activity	5/3132	26/18639	0.192307692307692	1.14445181255526	0.449197061960248	0.90192000352772
GO:0031369	translation initiation factor binding	6/3132	32/18639	0.1875	1.11584051724138	0.455766996672788	0.912247243731605
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/3132	32/18639	0.1875	1.11584051724138	0.455766996672788	0.912247243731605
GO:0004521	RNA endonuclease activity	13/3132	73/18639	0.178082191780822	1.05979373327035	0.457124967377032	0.913535676992538
GO:0004865	protein serine/threonine phosphatase inhibitor activity	3/3132	15/18639	0.2	1.19022988505747	0.473623509139064	0.936266565979695
GO:0005523	tropomyosin binding	3/3132	15/18639	0.2	1.19022988505747	0.473623509139064	0.936266565979695
GO:0008252	nucleotidase activity	3/3132	15/18639	0.2	1.19022988505747	0.473623509139064	0.936266565979695
GO:0031005	filamin binding	3/3132	15/18639	0.2	1.19022988505747	0.473623509139064	0.936266565979695
GO:0050700	CARD domain binding	3/3132	15/18639	0.2	1.19022988505747	0.473623509139064	0.936266565979695
GO:0051371	muscle alpha-actinin binding	3/3132	15/18639	0.2	1.19022988505747	0.473623509139064	0.936266565979695
GO:0061578	K63-linked deubiquitinase activity	3/3132	15/18639	0.2	1.19022988505747	0.473623509139064	0.936266565979695
GO:0004519	endonuclease activity	22/3132	127/18639	0.173228346456693	1.03090777445923	0.474455812389336	0.936464481552409
GO:0048306	calcium-dependent protein binding	14/3132	80/18639	0.175	1.04145114942529	0.479938512347881	0.941542778250471
GO:0001846	opsonin binding	4/3132	21/18639	0.19047619047619	1.13355227148331	0.479973331836831	0.941542778250471
GO:0019200	carbohydrate kinase activity	4/3132	21/18639	0.19047619047619	1.13355227148331	0.479973331836831	0.941542778250471
GO:1904047	S-adenosyl-L-methionine binding	4/3132	21/18639	0.19047619047619	1.13355227148331	0.479973331836831	0.941542778250471
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	5/3132	27/18639	0.185185185185185	1.10206470838655	0.484213613470046	0.948406143381606
GO:0008234	cysteine-type peptidase activity	32/3132	187/18639	0.171122994652406	1.01837851127912	0.485392459993472	0.949261401118732
GO:0019239	deaminase activity	6/3132	33/18639	0.181818181818182	1.08202716823406	0.487363215670018	0.951660386018248
GO:0004601	peroxidase activity	10/3132	57/18639	0.175438596491228	1.04406130268199	0.495226705675983	0.965541092316437
GO:0051213	dioxygenase activity	16/3132	93/18639	0.172043010752688	1.02385366456557	0.501842731366481	0.965824705574706
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	6/3132	34/18639	0.176470588235294	1.05020283975659	0.518345180997149	0.965824705574706
GO:0004177	aminopeptidase activity	7/3132	40/18639	0.175	1.04145114942529	0.518389531386998	0.965824705574706
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	7/3132	40/18639	0.175	1.04145114942529	0.518389531386998	0.965824705574706
GO:0030291	protein serine/threonine kinase inhibitor activity	8/3132	46/18639	0.173913043478261	1.03498250874563	0.51850716732764	0.965824705574706
GO:0030159	signaling receptor complex adaptor activity	9/3132	52/18639	0.173076923076923	1.03000663129973	0.51867404513317	0.965824705574706
GO:0004708	MAP kinase kinase activity	3/3132	16/18639	0.1875	1.11584051724138	0.519221917525044	0.965824705574706
GO:0005149	interleukin-1 receptor binding	3/3132	16/18639	0.1875	1.11584051724138	0.519221917525044	0.965824705574706
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/3132	16/18639	0.1875	1.11584051724138	0.519221917525044	0.965824705574706
GO:0022858	alanine transmembrane transporter activity	3/3132	16/18639	0.1875	1.11584051724138	0.519221917525044	0.965824705574706
GO:0140328	floppase activity	3/3132	16/18639	0.1875	1.11584051724138	0.519221917525044	0.965824705574706
GO:0098631	cell adhesion mediator activity	13/3132	76/18639	0.171052631578947	1.01795977011494	0.51959446603483	0.965824705574706
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0004382	GDP phosphatase activity	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0005031	tumor necrosis factor receptor activity	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0005131	growth hormone receptor binding	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0008190	eukaryotic initiation factor 4E binding	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0016783	sulfurtransferase activity	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0032356	oxidized DNA binding	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0033204	ribonuclease P RNA binding	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0042166	acetylcholine binding	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0051864	histone H3K36 demethylase activity	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:1990757	ubiquitin ligase activator activity	2/3132	10/18639	0.2	1.19022988505747	0.520291807772457	0.965824705574706
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	81/3132	484/18639	0.167355371900826	0.995956825306355	0.535558068047223	0.992722853670143
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	15/3132	89/18639	0.168539325842697	1.00300271212708	0.539098380538532	0.99570369318868
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	15/3132	89/18639	0.168539325842697	1.00300271212708	0.539098380538532	0.99570369318868
GO:0030165	PDZ domain binding	14/3132	83/18639	0.168674698795181	1.00380833679546	0.539501688334445	0.99570369318868
GO:0140299	molecular sensor activity	12/3132	71/18639	0.169014084507042	1.00582807187955	0.540576007322596	0.996248866521037
GO:0001727	lipid kinase activity	7/3132	41/18639	0.170731707317073	1.01604990187833	0.546315054682752	1
GO:0016417	S-acyltransferase activity	5/3132	29/18639	0.172413793103448	1.0260602457392	0.551609870135931	1
GO:0043236	laminin binding	5/3132	29/18639	0.172413793103448	1.0260602457392	0.551609870135931	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/3132	29/18639	0.172413793103448	1.0260602457392	0.551609870135931	1
GO:0000295	adenine nucleotide transmembrane transporter activity	4/3132	23/18639	0.173913043478261	1.03498250874563	0.555936675031946	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/3132	23/18639	0.173913043478261	1.03498250874563	0.555936675031946	1
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	4/3132	23/18639	0.173913043478261	1.03498250874563	0.555936675031946	1
GO:0140793	histone H2AXY142 phosphatase activity	15/3132	90/18639	0.166666666666667	0.991858237547893	0.55783070419403	1
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	3/3132	17/18639	0.176470588235294	1.05020283975659	0.562578549617916	1
GO:0004549	tRNA-specific ribonuclease activity	3/3132	17/18639	0.176470588235294	1.05020283975659	0.562578549617916	1
GO:0008429	phosphatidylethanolamine binding	3/3132	17/18639	0.176470588235294	1.05020283975659	0.562578549617916	1
GO:0016805	dipeptidase activity	3/3132	17/18639	0.176470588235294	1.05020283975659	0.562578549617916	1
GO:0045125	bioactive lipid receptor activity	3/3132	17/18639	0.176470588235294	1.05020283975659	0.562578549617916	1
GO:0046965	nuclear retinoid X receptor binding	3/3132	17/18639	0.176470588235294	1.05020283975659	0.562578549617916	1
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/3132	11/18639	0.181818181818182	1.08202716823406	0.574227909737561	1
GO:0001851	complement component C3b binding	2/3132	11/18639	0.181818181818182	1.08202716823406	0.574227909737561	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	2/3132	11/18639	0.181818181818182	1.08202716823406	0.574227909737561	1
GO:0005114	type II transforming growth factor beta receptor binding	2/3132	11/18639	0.181818181818182	1.08202716823406	0.574227909737561	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/3132	11/18639	0.181818181818182	1.08202716823406	0.574227909737561	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/3132	11/18639	0.181818181818182	1.08202716823406	0.574227909737561	1
GO:0019206	nucleoside kinase activity	2/3132	11/18639	0.181818181818182	1.08202716823406	0.574227909737561	1
GO:0019215	intermediate filament binding	2/3132	11/18639	0.181818181818182	1.08202716823406	0.574227909737561	1
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/3132	11/18639	0.181818181818182	1.08202716823406	0.574227909737561	1
GO:0032794	GTPase activating protein binding	2/3132	11/18639	0.181818181818182	1.08202716823406	0.574227909737561	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	2/3132	11/18639	0.181818181818182	1.08202716823406	0.574227909737561	1
GO:0140031	phosphorylation-dependent protein binding	2/3132	11/18639	0.181818181818182	1.08202716823406	0.574227909737561	1
GO:0004033	aldo-keto reductase (NADPH) activity	6/3132	36/18639	0.166666666666667	0.991858237547893	0.577898912993686	1
GO:0016835	carbon-oxygen lyase activity	13/3132	79/18639	0.164556962025316	0.979303069983995	0.579849220438357	1
GO:0001965	G-protein alpha-subunit binding	5/3132	30/18639	0.166666666666667	0.991858237547893	0.583647061901251	1
GO:0016769	transferase activity, transferring nitrogenous groups	5/3132	30/18639	0.166666666666667	0.991858237547893	0.583647061901251	1
GO:0033612	receptor serine/threonine kinase binding	5/3132	30/18639	0.166666666666667	0.991858237547893	0.583647061901251	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	11/3132	67/18639	0.164179104477612	0.977054383256133	0.584502278035733	1
GO:0098632	cell-cell adhesion mediator activity	9/3132	55/18639	0.163636363636364	0.973824451410658	0.59082740135101	1
GO:0005540	hyaluronic acid binding	4/3132	24/18639	0.166666666666667	0.991858237547893	0.591597925861868	1
GO:0060229	lipase activator activity	4/3132	24/18639	0.166666666666667	0.991858237547893	0.591597925861868	1
GO:0070300	phosphatidic acid binding	4/3132	24/18639	0.166666666666667	0.991858237547893	0.591597925861868	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/3132	24/18639	0.166666666666667	0.991858237547893	0.591597925861868	1
GO:0140612	DNA damage sensor activity	4/3132	24/18639	0.166666666666667	0.991858237547893	0.591597925861868	1
GO:0001216	DNA-binding transcription activator activity	81/3132	491/18639	0.164969450101833	0.981757848163495	0.592163871982096	1
GO:0035254	glutamate receptor binding	8/3132	49/18639	0.163265306122449	0.971616232699976	0.594930874640923	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	14/3132	86/18639	0.162790697674419	0.968791766907244	0.596691105243774	1
GO:0000400	four-way junction DNA binding	3/3132	18/18639	0.166666666666667	0.991858237547893	0.603459633344164	1
GO:0034185	apolipoprotein binding	3/3132	18/18639	0.166666666666667	0.991858237547893	0.603459633344164	1
GO:0035615	clathrin adaptor activity	3/3132	18/18639	0.166666666666667	0.991858237547893	0.603459633344164	1
GO:0050811	GABA receptor binding	3/3132	18/18639	0.166666666666667	0.991858237547893	0.603459633344164	1
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	3/3132	18/18639	0.166666666666667	0.991858237547893	0.603459633344164	1
GO:0098641	cadherin binding involved in cell-cell adhesion	3/3132	18/18639	0.166666666666667	0.991858237547893	0.603459633344164	1
GO:0019838	growth factor binding	22/3132	136/18639	0.161764705882353	0.962685936443543	0.61340758883889	1
GO:0008017	microtubule binding	45/3132	276/18639	0.16304347826087	0.970296101949025	0.613525192004933	1
GO:0030170	pyridoxal phosphate binding	9/3132	56/18639	0.160714285714286	0.956434729064039	0.613717354078534	1
GO:0008327	methyl-CpG binding	5/3132	31/18639	0.161290322580645	0.959862810530219	0.614401399313092	1
GO:0008081	phosphoric diester hydrolase activity	14/3132	87/18639	0.160919540229885	0.957656229356586	0.615053010928121	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	21/3132	130/18639	0.161538461538462	0.961339522546419	0.615183555869074	1
GO:0003720	telomerase activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0004526	ribonuclease P activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0004859	phospholipase inhibitor activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0005095	GTPase inhibitor activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0005247	voltage-gated chloride channel activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0008603	cAMP-dependent protein kinase regulator activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0016208	AMP binding	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0016273	arginine N-methyltransferase activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0016274	protein-arginine N-methyltransferase activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0016801	hydrolase activity, acting on ether bonds	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0016803	ether hydrolase activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/3132	12/18639	0.166666666666667	0.991858237547893	0.623588650508482	1
GO:0008013	beta-catenin binding	17/3132	106/18639	0.160377358490566	0.954429624810236	0.623941997080597	1
GO:0019205	nucleobase-containing compound kinase activity	7/3132	44/18639	0.159090909090909	0.946773772204807	0.625488857874635	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	7/3132	44/18639	0.159090909090909	0.946773772204807	0.625488857874635	1
GO:0001848	complement binding	4/3132	25/18639	0.16	0.952183908045977	0.625505192143469	1
GO:0005537	D-mannose binding	4/3132	25/18639	0.16	0.952183908045977	0.625505192143469	1
GO:0008483	transaminase activity	4/3132	25/18639	0.16	0.952183908045977	0.625505192143469	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	4/3132	25/18639	0.16	0.952183908045977	0.625505192143469	1
GO:0019707	protein-cysteine S-acyltransferase activity	4/3132	25/18639	0.16	0.952183908045977	0.625505192143469	1
GO:0042974	nuclear retinoic acid receptor binding	4/3132	25/18639	0.16	0.952183908045977	0.625505192143469	1
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	4/3132	25/18639	0.16	0.952183908045977	0.625505192143469	1
GO:0016247	channel regulator activity	27/3132	168/18639	0.160714285714286	0.956434729064039	0.632517550531859	1
GO:0005109	frizzled binding	6/3132	38/18639	0.157894736842105	0.939655172413793	0.633500876522818	1
GO:0070279	vitamin B6 binding	9/3132	57/18639	0.157894736842105	0.939655172413793	0.635934350654012	1
GO:0017022	myosin binding	12/3132	76/18639	0.157894736842105	0.939655172413793	0.640929803216298	1
GO:0005229	intracellularly calcium-gated chloride channel activity	3/3132	19/18639	0.157894736842105	0.939655172413793	0.641722667967596	1
GO:0042800	histone H3K4 methyltransferase activity	3/3132	19/18639	0.157894736842105	0.939655172413793	0.641722667967596	1
GO:0141147	intracellularly calcium-gated channel activity	3/3132	19/18639	0.157894736842105	0.939655172413793	0.641722667967596	1
GO:1990380	K48-linked deubiquitinase activity	3/3132	19/18639	0.157894736842105	0.939655172413793	0.641722667967596	1
GO:0016597	amino acid binding	8/3132	51/18639	0.156862745098039	0.933513635339193	0.642359627106699	1
GO:0008378	galactosyltransferase activity	5/3132	32/18639	0.15625	0.929867097701149	0.643778140542778	1
GO:0071813	lipoprotein particle binding	5/3132	32/18639	0.15625	0.929867097701149	0.643778140542778	1
GO:0071814	protein-lipid complex binding	5/3132	32/18639	0.15625	0.929867097701149	0.643778140542778	1
GO:0005227	calcium-activated cation channel activity	4/3132	26/18639	0.153846153846154	0.915561450044209	0.657561215813145	1
GO:0008157	protein phosphatase 1 binding	4/3132	26/18639	0.153846153846154	0.915561450044209	0.657561215813145	1
GO:0034237	protein kinase A regulatory subunit binding	4/3132	26/18639	0.153846153846154	0.915561450044209	0.657561215813145	1
GO:0043548	phosphatidylinositol 3-kinase binding	4/3132	26/18639	0.153846153846154	0.915561450044209	0.657561215813145	1
GO:0050750	low-density lipoprotein particle receptor binding	4/3132	26/18639	0.153846153846154	0.915561450044209	0.657561215813145	1
GO:0051139	metal cation:proton antiporter activity	4/3132	26/18639	0.153846153846154	0.915561450044209	0.657561215813145	1
GO:0141108	transporter regulator activity	27/3132	170/18639	0.158823529411765	0.945182555780933	0.657986523714336	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	8/3132	52/18639	0.153846153846154	0.915561450044209	0.66484791473825	1
GO:0101005	deubiquitinase activity	18/3132	115/18639	0.156521739130435	0.931484257871065	0.667857799952827	1
GO:0003964	RNA-directed DNA polymerase activity	2/3132	13/18639	0.153846153846154	0.915561450044209	0.66838833423603	1
GO:0005035	death receptor activity	2/3132	13/18639	0.153846153846154	0.915561450044209	0.66838833423603	1
GO:0005172	vascular endothelial growth factor receptor binding	2/3132	13/18639	0.153846153846154	0.915561450044209	0.66838833423603	1
GO:0008253	5'-nucleotidase activity	2/3132	13/18639	0.153846153846154	0.915561450044209	0.66838833423603	1
GO:0043560	insulin receptor substrate binding	2/3132	13/18639	0.153846153846154	0.915561450044209	0.66838833423603	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/3132	13/18639	0.153846153846154	0.915561450044209	0.66838833423603	1
GO:0071837	HMG box domain binding	2/3132	13/18639	0.153846153846154	0.915561450044209	0.66838833423603	1
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/3132	13/18639	0.153846153846154	0.915561450044209	0.66838833423603	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	5/3132	33/18639	0.151515151515152	0.901689306861721	0.671709377127199	1
GO:0004180	carboxypeptidase activity	7/3132	46/18639	0.152173913043478	0.905609695152424	0.673710724991482	1
GO:0031490	chromatin DNA binding	20/3132	128/18639	0.15625	0.929867097701149	0.675746894030874	1
GO:0001972	retinoic acid binding	3/3132	20/18639	0.15	0.892672413793103	0.677300859405265	1
GO:0016408	C-acyltransferase activity	3/3132	20/18639	0.15	0.892672413793103	0.677300859405265	1
GO:0042288	MHC class I protein binding	3/3132	20/18639	0.15	0.892672413793103	0.677300859405265	1
GO:0140664	ATP-dependent DNA damage sensor activity	3/3132	20/18639	0.15	0.892672413793103	0.677300859405265	1
GO:0050997	quaternary ammonium group binding	6/3132	40/18639	0.15	0.892672413793103	0.684540141680572	1
GO:0071949	FAD binding	6/3132	40/18639	0.15	0.892672413793103	0.684540141680572	1
GO:1901505	carbohydrate derivative transmembrane transporter activity	8/3132	53/18639	0.150943396226415	0.898286705703752	0.686466719237962	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	4/3132	27/18639	0.148148148148148	0.881651766709238	0.687708624916293	1
GO:0005044	scavenger receptor activity	4/3132	27/18639	0.148148148148148	0.881651766709238	0.687708624916293	1
GO:0005104	fibroblast growth factor receptor binding	4/3132	27/18639	0.148148148148148	0.881651766709238	0.687708624916293	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/3132	27/18639	0.148148148148148	0.881651766709238	0.687708624916293	1
GO:0023026	MHC class II protein complex binding	4/3132	27/18639	0.148148148148148	0.881651766709238	0.687708624916293	1
GO:0005506	iron ion binding	24/3132	154/18639	0.155844155844156	0.927451858486341	0.690308495006304	1
GO:0008235	metalloexopeptidase activity	10/3132	66/18639	0.151515151515152	0.901689306861721	0.690381003907313	1
GO:0033218	amide binding	39/3132	247/18639	0.157894736842105	0.939655172413793	0.691781216160797	1
GO:0001784	phosphotyrosine residue binding	7/3132	47/18639	0.148936170212766	0.886341403766202	0.696306352928891	1
GO:0043495	protein-membrane adaptor activity	7/3132	47/18639	0.148936170212766	0.886341403766202	0.696306352928891	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	5/3132	34/18639	0.147058823529412	0.875169033130494	0.698151479908242	1
GO:0050660	flavin adenine dinucleotide binding	13/3132	86/18639	0.151162790697674	0.899592354985298	0.705914714144604	1
GO:0042169	SH2 domain binding	6/3132	41/18639	0.146341463414634	0.870899915895711	0.708235870880198	1
GO:0004705	JUN kinase activity	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0005161	platelet-derived growth factor receptor binding	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0008195	phosphatidate phosphatase activity	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0008494	translation activator activity	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0008559	ABC-type xenobiotic transporter activity	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0031404	chloride ion binding	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0032036	myosin heavy chain binding	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0034236	protein kinase A catalytic subunit binding	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0042043	neurexin family protein binding	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0044548	S100 protein binding	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0070742	C2H2 zinc finger domain binding	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/3132	14/18639	0.142857142857143	0.850164203612479	0.70876561459479	1
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/3132	21/18639	0.142857142857143	0.850164203612479	0.710188780666671	1
GO:0010314	phosphatidylinositol-5-phosphate binding	3/3132	21/18639	0.142857142857143	0.850164203612479	0.710188780666671	1
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	3/3132	21/18639	0.142857142857143	0.850164203612479	0.710188780666671	1
GO:0046875	ephrin receptor binding	4/3132	28/18639	0.142857142857143	0.850164203612479	0.715924442285318	1
GO:0051119	sugar transmembrane transporter activity	4/3132	28/18639	0.142857142857143	0.850164203612479	0.715924442285318	1
GO:0051393	alpha-actinin binding	4/3132	28/18639	0.142857142857143	0.850164203612479	0.715924442285318	1
GO:0016836	hydro-lyase activity	9/3132	61/18639	0.147540983606557	0.878038439796495	0.717321106196819	1
GO:0019955	cytokine binding	22/3132	144/18639	0.152777777777778	0.909203384418902	0.721571017087788	1
GO:0005126	cytokine receptor binding	43/3132	275/18639	0.156363636363636	0.930543364681296	0.722886080851301	1
GO:0008374	O-acyltransferase activity	8/3132	55/18639	0.145454545454545	0.865621734587252	0.726994776987474	1
GO:0030971	receptor tyrosine kinase binding	12/3132	81/18639	0.148148148148148	0.881651766709238	0.728427282133465	1
GO:0042056	chemoattractant activity	6/3132	42/18639	0.142857142857143	0.850164203612479	0.730686661899008	1
GO:0016763	pentosyltransferase activity	7/3132	49/18639	0.142857142857143	0.850164203612479	0.738342260610101	1
GO:0008093	cytoskeletal anchor activity	3/3132	22/18639	0.136363636363636	0.811520376175549	0.740429524657421	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/3132	22/18639	0.136363636363636	0.811520376175549	0.740429524657421	1
GO:0031683	G-protein beta/gamma-subunit complex binding	3/3132	22/18639	0.136363636363636	0.811520376175549	0.740429524657421	1
GO:0061133	endopeptidase activator activity	3/3132	22/18639	0.136363636363636	0.811520376175549	0.740429524657421	1
GO:0035250	UDP-galactosyltransferase activity	4/3132	29/18639	0.137931034482759	0.820848196591359	0.74221477382922	1
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/3132	15/18639	0.133333333333333	0.793486590038314	0.74494132312644	1
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/3132	15/18639	0.133333333333333	0.793486590038314	0.74494132312644	1
GO:0005041	low-density lipoprotein particle receptor activity	2/3132	15/18639	0.133333333333333	0.793486590038314	0.74494132312644	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	2/3132	15/18639	0.133333333333333	0.793486590038314	0.74494132312644	1
GO:0008242	omega peptidase activity	2/3132	15/18639	0.133333333333333	0.793486590038314	0.74494132312644	1
GO:0016846	carbon-sulfur lyase activity	2/3132	15/18639	0.133333333333333	0.793486590038314	0.74494132312644	1
GO:0030553	cGMP binding	2/3132	15/18639	0.133333333333333	0.793486590038314	0.74494132312644	1
GO:0045504	dynein heavy chain binding	2/3132	15/18639	0.133333333333333	0.793486590038314	0.74494132312644	1
GO:0120283	protein serine/threonine kinase binding	2/3132	15/18639	0.133333333333333	0.793486590038314	0.74494132312644	1
GO:0004190	aspartic-type endopeptidase activity	5/3132	36/18639	0.138888888888889	0.826548531289911	0.746499125623497	1
GO:0004843	cysteine-type deubiquitinase activity	16/3132	108/18639	0.148148148148148	0.881651766709238	0.747904010801132	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6/3132	43/18639	0.13953488372093	0.830392943063352	0.751887581968627	1
GO:0008238	exopeptidase activity	15/3132	102/18639	0.147058823529412	0.875169033130494	0.753549284534476	1
GO:0099106	ion channel regulator activity	24/3132	160/18639	0.15	0.892672413793103	0.760395887757819	1
GO:0005085	guanyl-nucleotide exchange factor activity	35/3132	230/18639	0.152173913043478	0.905609695152424	0.766446095038377	1
GO:0022839	monoatomic ion-gated channel activity	4/3132	30/18639	0.133333333333333	0.793486590038314	0.766609806433522	1
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/3132	23/18639	0.130434782608696	0.77623688155922	0.768103452101243	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	3/3132	23/18639	0.130434782608696	0.77623688155922	0.768103452101243	1
GO:0005212	structural constituent of eye lens	3/3132	23/18639	0.130434782608696	0.77623688155922	0.768103452101243	1
GO:0030551	cyclic nucleotide binding	5/3132	37/18639	0.135135135135135	0.804209381795589	0.768414751552942	1
GO:0070001	aspartic-type peptidase activity	5/3132	37/18639	0.135135135135135	0.804209381795589	0.768414751552942	1
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/3132	16/18639	0.125	0.74389367816092	0.777186952498068	1
GO:0004707	MAP kinase activity	2/3132	16/18639	0.125	0.74389367816092	0.777186952498068	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/3132	16/18639	0.125	0.74389367816092	0.777186952498068	1
GO:0015385	sodium:proton antiporter activity	2/3132	16/18639	0.125	0.74389367816092	0.777186952498068	1
GO:0015562	efflux transmembrane transporter activity	2/3132	16/18639	0.125	0.74389367816092	0.777186952498068	1
GO:0055102	lipase inhibitor activity	2/3132	16/18639	0.125	0.74389367816092	0.777186952498068	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/3132	16/18639	0.125	0.74389367816092	0.777186952498068	1
GO:0140327	flippase activity	2/3132	16/18639	0.125	0.74389367816092	0.777186952498068	1
GO:0072341	modified amino acid binding	13/3132	91/18639	0.142857142857143	0.850164203612479	0.780074365187348	1
GO:0038024	cargo receptor activity	9/3132	65/18639	0.138461538461538	0.824005305039788	0.78578681881008	1
GO:0016878	acid-thiol ligase activity	4/3132	31/18639	0.129032258064516	0.767890248424175	0.789159200080993	1
GO:0017147	Wnt-protein binding	4/3132	31/18639	0.129032258064516	0.767890248424175	0.789159200080993	1
GO:0047499	calcium-independent phospholipase A2 activity	4/3132	31/18639	0.129032258064516	0.767890248424175	0.789159200080993	1
GO:0070325	lipoprotein particle receptor binding	4/3132	31/18639	0.129032258064516	0.767890248424175	0.789159200080993	1
GO:0004622	lysophospholipase activity	3/3132	24/18639	0.125	0.74389367816092	0.793318527278296	1
GO:0015149	hexose transmembrane transporter activity	3/3132	24/18639	0.125	0.74389367816092	0.793318527278296	1
GO:0055056	D-glucose transmembrane transporter activity	3/3132	24/18639	0.125	0.74389367816092	0.793318527278296	1
GO:0070840	dynein complex binding	3/3132	24/18639	0.125	0.74389367816092	0.793318527278296	1
GO:0004550	nucleoside diphosphate kinase activity	2/3132	17/18639	0.117647058823529	0.700135226504395	0.805801406215421	1
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/3132	17/18639	0.117647058823529	0.700135226504395	0.805801406215421	1
GO:0015278	intracellularly gated calcium channel activity	2/3132	17/18639	0.117647058823529	0.700135226504395	0.805801406215421	1
GO:0036041	long-chain fatty acid binding	2/3132	17/18639	0.117647058823529	0.700135226504395	0.805801406215421	1
GO:0038191	neuropilin binding	2/3132	17/18639	0.117647058823529	0.700135226504395	0.805801406215421	1
GO:1990226	histone methyltransferase binding	2/3132	17/18639	0.117647058823529	0.700135226504395	0.805801406215421	1
GO:0000217	DNA secondary structure binding	5/3132	39/18639	0.128205128205128	0.76296787503684	0.807861938598024	1
GO:0047498	calcium-dependent phospholipase A2 activity	4/3132	32/18639	0.125	0.74389367816092	0.809927922872167	1
GO:0050840	extracellular matrix binding	9/3132	67/18639	0.134328358208955	0.799408131755018	0.815110413517595	1
GO:0042562	hormone binding	13/3132	94/18639	0.138297872340426	0.823031303497188	0.817731505174044	1
GO:0001618	virus receptor activity	11/3132	81/18639	0.135802469135802	0.808180786150135	0.821889344555882	1
GO:0019905	syntaxin binding	8/3132	61/18639	0.131147540983607	0.78047861315244	0.826462937739536	1
GO:0015172	acidic amino acid transmembrane transporter activity	2/3132	18/18639	0.111111111111111	0.661238825031928	0.831094127824328	1
GO:0016854	racemase and epimerase activity	2/3132	18/18639	0.111111111111111	0.661238825031928	0.831094127824328	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/3132	18/18639	0.111111111111111	0.661238825031928	0.831094127824328	1
GO:0017075	syntaxin-1 binding	2/3132	18/18639	0.111111111111111	0.661238825031928	0.831094127824328	1
GO:0030228	lipoprotein particle receptor activity	2/3132	18/18639	0.111111111111111	0.661238825031928	0.831094127824328	1
GO:0140272	exogenous protein binding	11/3132	82/18639	0.134146341463415	0.798324922904401	0.833934195517059	1
GO:0004857	enzyme inhibitor activity	63/3132	416/18639	0.151442307692308	0.901255802387268	0.8368137691347	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	26/3132	181/18639	0.143646408839779	0.854861243411443	0.836835202311558	1
GO:0015145	monosaccharide transmembrane transporter activity	3/3132	26/18639	0.115384615384615	0.686671087533157	0.836894461462519	1
GO:0000182	rDNA binding	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0005345	purine nucleobase transmembrane transporter activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0008239	dipeptidyl-peptidase activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0015187	glycine transmembrane transporter activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0015203	polyamine transmembrane transporter activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0015643	toxic substance binding	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0016868	intramolecular phosphotransferase activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0031419	cobalamin binding	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0035256	G protein-coupled glutamate receptor binding	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0042975	peroxisome proliferator activated receptor binding	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0043121	neurotrophin binding	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0043295	glutathione binding	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0045322	unmethylated CpG binding	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0070097	delta-catenin binding	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0070739	protein-glutamic acid ligase activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0070740	tubulin-glutamic acid ligase activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0140135	mechanosensitive monoatomic cation channel activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0140940	histone H2A methyltransferase activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0140999	histone H3K4 trimethyltransferase activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0141109	transporter activator activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:1990259	histone H2AQ104 methyltransferase activity	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:1990763	arrestin family protein binding	1/3132	10/18639	0.1	0.595114942528736	0.841203862549821	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	5/3132	41/18639	0.121951219512195	0.725749929913092	0.841763153057307	1
GO:0017080	sodium channel regulator activity	5/3132	41/18639	0.121951219512195	0.725749929913092	0.841763153057307	1
GO:0140828	metal cation:monoatomic cation antiporter activity	5/3132	41/18639	0.121951219512195	0.725749929913092	0.841763153057307	1
GO:0008376	acetylgalactosaminyltransferase activity	4/3132	34/18639	0.117647058823529	0.700135226504395	0.84643802586657	1
GO:0051427	hormone receptor binding	4/3132	34/18639	0.117647058823529	0.700135226504395	0.84643802586657	1
GO:0090482	vitamin transmembrane transporter activity	4/3132	34/18639	0.117647058823529	0.700135226504395	0.84643802586657	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	18/3132	130/18639	0.138461538461538	0.824005305039788	0.847304806744177	1
GO:0016782	transferase activity, transferring sulphur-containing groups	9/3132	70/18639	0.128571428571429	0.765147783251231	0.853227864011374	1
GO:0015245	fatty acid transmembrane transporter activity	2/3132	19/18639	0.105263157894737	0.626436781609195	0.853373123101591	1
GO:0031420	alkali metal ion binding	2/3132	19/18639	0.105263157894737	0.626436781609195	0.853373123101591	1
GO:0042577	lipid phosphatase activity	2/3132	19/18639	0.105263157894737	0.626436781609195	0.853373123101591	1
GO:0042834	peptidoglycan binding	2/3132	19/18639	0.105263157894737	0.626436781609195	0.853373123101591	1
GO:0043395	heparan sulfate proteoglycan binding	2/3132	19/18639	0.105263157894737	0.626436781609195	0.853373123101591	1
GO:0008395	steroid hydroxylase activity	3/3132	27/18639	0.111111111111111	0.661238825031928	0.855542691030797	1
GO:0031492	nucleosomal DNA binding	5/3132	42/18639	0.119047619047619	0.708470169677066	0.85677348970032	1
GO:0016758	hexosyltransferase activity	28/3132	197/18639	0.142131979695431	0.845848649279421	0.859356127372581	1
GO:0004623	phospholipase A2 activity	4/3132	35/18639	0.114285714285714	0.680131362889984	0.862354877020333	1
GO:0052689	carboxylic ester hydrolase activity	12/3132	92/18639	0.130434782608696	0.77623688155922	0.867802189471822	1
GO:0003953	NAD+ nucleosidase activity	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0005225	volume-sensitive anion channel activity	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0005536	D-glucose binding	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0008046	axon guidance receptor activity	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0008172	S-methyltransferase activity	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0008199	ferric iron binding	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0015173	aromatic amino acid transmembrane transporter activity	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0015205	nucleobase transmembrane transporter activity	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0042608	T cell receptor binding	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0047676	arachidonate-CoA ligase activity	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0048185	activin binding	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0050786	RAGE receptor binding	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0050998	nitric-oxide synthase binding	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0180030	inositol phosphate kinase activity	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:1900750	oligopeptide binding	1/3132	11/18639	0.0909090909090909	0.541013584117032	0.867901457831047	1
GO:0050698	proteoglycan sulfotransferase activity	3/3132	28/18639	0.107142857142857	0.63762315270936	0.872296880880254	1
GO:0003774	cytoskeletal motor activity	21/3132	153/18639	0.137254901960784	0.816824430921794	0.872702737159902	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/3132	20/18639	0.1	0.595114942528736	0.872936707956738	1
GO:0030627	pre-mRNA 5'-splice site binding	2/3132	20/18639	0.1	0.595114942528736	0.872936707956738	1
GO:0003779	actin binding	66/3132	443/18639	0.148984198645598	0.886627228146649	0.875876967682542	1
GO:0003785	actin monomer binding	3/3132	29/18639	0.103448275862069	0.61563614744352	0.887306354770758	1
GO:0004181	metallocarboxypeptidase activity	3/3132	29/18639	0.103448275862069	0.61563614744352	0.887306354770758	1
GO:0022829	wide pore channel activity	4/3132	37/18639	0.108108108108108	0.643367505436471	0.889978917992451	1
GO:0023023	MHC protein complex binding	4/3132	37/18639	0.108108108108108	0.643367505436471	0.889978917992451	1
GO:0043394	proteoglycan binding	4/3132	37/18639	0.108108108108108	0.643367505436471	0.889978917992451	1
GO:0008373	sialyltransferase activity	2/3132	21/18639	0.0952380952380952	0.566776135741653	0.890068068724114	1
GO:0051428	peptide hormone receptor binding	2/3132	21/18639	0.0952380952380952	0.566776135741653	0.890068068724114	1
GO:0004032	aldose reductase (NADPH) activity	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0004126	cytidine deaminase activity	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0005025	transforming growth factor beta receptor activity, type I	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0005026	transforming growth factor beta receptor activity, type II	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0015368	calcium:monoatomic cation antiporter activity	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0016361	activin receptor activity, type I	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0016362	activin receptor activity, type II	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0016840	carbon-nitrogen lyase activity	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0017002	activin receptor activity	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0017166	vinculin binding	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0036009	protein-glutamine N-methyltransferase activity	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0042301	phosphate ion binding	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0070410	co-SMAD binding	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0097371	MDM2/MDM4 family protein binding	1/3132	12/18639	0.0833333333333333	0.495929118773946	0.89011171304219	1
GO:0051018	protein kinase A binding	6/3132	53/18639	0.113207547169811	0.673715029277814	0.9004956088183	1
GO:1990782	protein tyrosine kinase binding	15/3132	117/18639	0.128205128205128	0.76296787503684	0.903389913897555	1
GO:0008970	phospholipase A1 activity	2/3132	22/18639	0.0909090909090909	0.541013584117032	0.905031923130783	1
GO:0016881	acid-amino acid ligase activity	2/3132	22/18639	0.0909090909090909	0.541013584117032	0.905031923130783	1
GO:0002161	aminoacyl-tRNA editing activity	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0005542	folic acid binding	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0008417	fucosyltransferase activity	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0009982	pseudouridine synthase activity	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0017154	semaphorin receptor activity	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0035325	Toll-like receptor binding	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0035673	oligopeptide transmembrane transporter activity	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0039706	co-receptor binding	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0045159	myosin II binding	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0046974	histone H3K9 methyltransferase activity	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0061459	L-arginine transmembrane transporter activity	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0070123	transforming growth factor beta receptor activity, type III	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0070700	BMP receptor binding	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0089720	caspase binding	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0140333	glycerophospholipid flippase activity	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/3132	13/18639	0.0769230769230769	0.457780725022104	0.908588661276036	1
GO:0001540	amyloid-beta binding	10/3132	83/18639	0.120481927710843	0.717005954853898	0.909486277282698	1
GO:0005504	fatty acid binding	5/3132	47/18639	0.106382978723404	0.633101002690144	0.915021241381975	1
GO:0140359	ABC-type transporter activity	5/3132	47/18639	0.106382978723404	0.633101002690144	0.915021241381975	1
GO:0004602	glutathione peroxidase activity	2/3132	23/18639	0.0869565217391304	0.517491254372814	0.918072729895501	1
GO:0043274	phospholipase binding	2/3132	23/18639	0.0869565217391304	0.517491254372814	0.918072729895501	1
GO:0140103	catalytic activity, acting on a glycoprotein	2/3132	23/18639	0.0869565217391304	0.517491254372814	0.918072729895501	1
GO:0016757	glycosyltransferase activity	37/3132	267/18639	0.138576779026217	0.824691118860046	0.918842594461461	1
GO:0015144	carbohydrate transmembrane transporter activity	4/3132	40/18639	0.1	0.595114942528736	0.922302443438523	1
GO:0042910	xenobiotic transmembrane transporter activity	3/3132	32/18639	0.09375	0.55792025862069	0.923298173615563	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	5/3132	48/18639	0.104166666666667	0.619911398467433	0.923779806738001	1
GO:0038187	pattern recognition receptor activity	5/3132	48/18639	0.104166666666667	0.619911398467433	0.923779806738001	1
GO:0008331	high voltage-gated calcium channel activity	1/3132	14/18639	0.0714285714285714	0.42508210180624	0.923959664866902	1
GO:0015386	potassium:proton antiporter activity	1/3132	14/18639	0.0714285714285714	0.42508210180624	0.923959664866902	1
GO:0015926	glucosidase activity	1/3132	14/18639	0.0714285714285714	0.42508210180624	0.923959664866902	1
GO:0019992	diacylglycerol binding	1/3132	14/18639	0.0714285714285714	0.42508210180624	0.923959664866902	1
GO:0043176	amine binding	1/3132	14/18639	0.0714285714285714	0.42508210180624	0.923959664866902	1
GO:0098821	BMP receptor activity	1/3132	14/18639	0.0714285714285714	0.42508210180624	0.923959664866902	1
GO:1901474	azole transmembrane transporter activity	1/3132	14/18639	0.0714285714285714	0.42508210180624	0.923959664866902	1
GO:0020037	heme binding	18/3132	142/18639	0.126760563380282	0.754371053909665	0.928421000366231	1
GO:0005315	phosphate transmembrane transporter activity	2/3132	24/18639	0.0833333333333333	0.495929118773946	0.92941402104252	1
GO:0015295	solute:proton symporter activity	2/3132	24/18639	0.0833333333333333	0.495929118773946	0.92941402104252	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/3132	24/18639	0.0833333333333333	0.495929118773946	0.92941402104252	1
GO:0019957	C-C chemokine binding	2/3132	24/18639	0.0833333333333333	0.495929118773946	0.92941402104252	1
GO:0030215	semaphorin receptor binding	2/3132	24/18639	0.0833333333333333	0.495929118773946	0.92941402104252	1
GO:0030552	cAMP binding	2/3132	24/18639	0.0833333333333333	0.495929118773946	0.92941402104252	1
GO:0019956	chemokine binding	3/3132	33/18639	0.0909090909090909	0.541013584117032	0.932728735989972	1
GO:0030296	protein tyrosine kinase activator activity	3/3132	33/18639	0.0909090909090909	0.541013584117032	0.932728735989972	1
GO:0019842	vitamin binding	19/3132	150/18639	0.126666666666667	0.753812260536398	0.93361344363888	1
GO:0004467	long-chain fatty acid-CoA ligase activity	1/3132	15/18639	0.0666666666666667	0.396743295019157	0.936746689276934	1
GO:0010181	FMN binding	1/3132	15/18639	0.0666666666666667	0.396743295019157	0.936746689276934	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/3132	15/18639	0.0666666666666667	0.396743295019157	0.936746689276934	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/3132	15/18639	0.0666666666666667	0.396743295019157	0.936746689276934	1
GO:0034483	heparan sulfate sulfotransferase activity	1/3132	15/18639	0.0666666666666667	0.396743295019157	0.936746689276934	1
GO:0047372	monoacylglycerol lipase activity	1/3132	15/18639	0.0666666666666667	0.396743295019157	0.936746689276934	1
GO:0048531	beta-1,3-galactosyltransferase activity	1/3132	15/18639	0.0666666666666667	0.396743295019157	0.936746689276934	1
GO:0008307	structural constituent of muscle	4/3132	42/18639	0.0952380952380952	0.566776135741653	0.938823699439447	1
GO:0019894	kinesin binding	4/3132	42/18639	0.0952380952380952	0.566776135741653	0.938823699439447	1
GO:0005251	delayed rectifier potassium channel activity	2/3132	25/18639	0.08	0.476091954022989	0.93925853036034	1
GO:0015645	fatty acid ligase activity	2/3132	25/18639	0.08	0.476091954022989	0.93925853036034	1
GO:0015662	P-type ion transporter activity	2/3132	25/18639	0.08	0.476091954022989	0.93925853036034	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/3132	25/18639	0.08	0.476091954022989	0.93925853036034	1
GO:0120515	fatty acid-CoA ligase activity	2/3132	25/18639	0.08	0.476091954022989	0.93925853036034	1
GO:0140358	P-type transmembrane transporter activity	2/3132	25/18639	0.08	0.476091954022989	0.93925853036034	1
GO:0046906	tetrapyrrole binding	19/3132	152/18639	0.125	0.74389367816092	0.942031585477893	1
GO:0005516	calmodulin binding	27/3132	207/18639	0.130434782608696	0.77623688155922	0.943093812988914	1
GO:0005021	vascular endothelial growth factor receptor activity	5/3132	51/18639	0.0980392156862745	0.583446022086996	0.945434126419641	1
GO:0005030	neurotrophin receptor activity	5/3132	51/18639	0.0980392156862745	0.583446022086996	0.945434126419641	1
GO:0008375	acetylglucosaminyltransferase activity	4/3132	43/18639	0.0930232558139535	0.553595295375568	0.945823641224678	1
GO:0015459	potassium channel regulator activity	6/3132	59/18639	0.101694915254237	0.605201636469901	0.946330126955425	1
GO:0016874	ligase activity	21/3132	167/18639	0.125748502994012	0.74834813132356	0.946463779581704	1
GO:0005024	transforming growth factor beta receptor activity	1/3132	16/18639	0.0625	0.37194683908046	0.947384005062192	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/3132	16/18639	0.0625	0.37194683908046	0.947384005062192	1
GO:0030507	spectrin binding	2/3132	26/18639	0.0769230769230769	0.457780725022104	0.947788869435158	1
GO:0034061	DNA polymerase activity	3/3132	35/18639	0.0857142857142857	0.510098522167488	0.948459878577808	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	6/3132	60/18639	0.1	0.595114942528736	0.951783684712505	1
GO:0016405	CoA-ligase activity	2/3132	27/18639	0.0740740740740741	0.440825883354619	0.955168563707507	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/3132	17/18639	0.0588235294117647	0.350067613252197	0.956232917490116	1
GO:0008569	minus-end-directed microtubule motor activity	1/3132	17/18639	0.0588235294117647	0.350067613252197	0.956232917490116	1
GO:0019198	transmembrane receptor protein phosphatase activity	1/3132	17/18639	0.0588235294117647	0.350067613252197	0.956232917490116	1
GO:0030169	low-density lipoprotein particle binding	1/3132	17/18639	0.0588235294117647	0.350067613252197	0.956232917490116	1
GO:0030548	acetylcholine receptor regulator activity	1/3132	17/18639	0.0588235294117647	0.350067613252197	0.956232917490116	1
GO:0045236	CXCR chemokine receptor binding	1/3132	17/18639	0.0588235294117647	0.350067613252197	0.956232917490116	1
GO:0070492	oligosaccharide binding	1/3132	17/18639	0.0588235294117647	0.350067613252197	0.956232917490116	1
GO:0005003	ephrin receptor activity	5/3132	53/18639	0.0943396226415094	0.561429191064845	0.956601151736273	1
GO:0005005	transmembrane-ephrin receptor activity	5/3132	53/18639	0.0943396226415094	0.561429191064845	0.956601151736273	1
GO:0038064	collagen receptor activity	5/3132	53/18639	0.0943396226415094	0.561429191064845	0.956601151736273	1
GO:0015297	antiporter activity	16/3132	135/18639	0.118518518518519	0.70532141336739	0.956709501062723	1
GO:0015026	coreceptor activity	6/3132	61/18639	0.0983606557377049	0.58535895986433	0.956732018051914	1
GO:0008009	chemokine activity	4/3132	45/18639	0.0888888888888889	0.528991060025543	0.957670048368503	1
GO:0061134	peptidase regulator activity	29/3132	226/18639	0.128318584070796	0.763643067846608	0.958922460026744	1
GO:0016866	intramolecular transferase activity	2/3132	28/18639	0.0714285714285714	0.42508210180624	0.961543308540373	1
GO:0045499	chemorepellent activity	2/3132	28/18639	0.0714285714285714	0.42508210180624	0.961543308540373	1
GO:0051959	dynein light intermediate chain binding	2/3132	28/18639	0.0714285714285714	0.42508210180624	0.961543308540373	1
GO:0008201	heparin binding	21/3132	172/18639	0.122093023255814	0.726593825180433	0.961928542817144	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	4/3132	46/18639	0.0869565217391304	0.517491254372814	0.962649306526361	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/3132	18/18639	0.0555555555555556	0.330619412515964	0.963594022764574	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/3132	18/18639	0.0555555555555556	0.330619412515964	0.963594022764574	1
GO:0099602	neurotransmitter receptor regulator activity	1/3132	18/18639	0.0555555555555556	0.330619412515964	0.963594022764574	1
GO:0008194	UDP-glycosyltransferase activity	17/3132	145/18639	0.117241379310345	0.697720967102656	0.965245630833011	1
GO:0005501	retinoid binding	3/3132	38/18639	0.0789473684210526	0.469827586206897	0.965748232570414	1
GO:0019840	isoprenoid binding	3/3132	38/18639	0.0789473684210526	0.469827586206897	0.965748232570414	1
GO:0042887	amide transmembrane transporter activity	3/3132	38/18639	0.0789473684210526	0.469827586206897	0.965748232570414	1
GO:0004629	phospholipase C activity	2/3132	29/18639	0.0689655172413793	0.41042409829568	0.967042342152937	1
GO:0099604	ligand-gated calcium channel activity	2/3132	29/18639	0.0689655172413793	0.41042409829568	0.967042342152937	1
GO:0004175	endopeptidase activity	55/3132	405/18639	0.135802469135802	0.808180786150135	0.968427982569833	1
GO:0042379	chemokine receptor binding	7/3132	72/18639	0.0972222222222222	0.578583971902937	0.96905703101717	1
GO:0005178	integrin binding	19/3132	161/18639	0.118012422360248	0.702309559505961	0.969550227851071	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/3132	19/18639	0.0526315789473684	0.313218390804598	0.969717406079184	1
GO:0005520	insulin-like growth factor binding	1/3132	19/18639	0.0526315789473684	0.313218390804598	0.969717406079184	1
GO:0008381	mechanosensitive monoatomic ion channel activity	1/3132	19/18639	0.0526315789473684	0.313218390804598	0.969717406079184	1
GO:0008574	plus-end-directed microtubule motor activity	1/3132	19/18639	0.0526315789473684	0.313218390804598	0.969717406079184	1
GO:0022821	solute:potassium antiporter activity	1/3132	19/18639	0.0526315789473684	0.313218390804598	0.969717406079184	1
GO:0030506	ankyrin binding	1/3132	19/18639	0.0526315789473684	0.313218390804598	0.969717406079184	1
GO:0001968	fibronectin binding	2/3132	30/18639	0.0666666666666667	0.396743295019157	0.971779860709305	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/3132	30/18639	0.0666666666666667	0.396743295019157	0.971779860709305	1
GO:0048019	receptor antagonist activity	2/3132	30/18639	0.0666666666666667	0.396743295019157	0.971779860709305	1
GO:0005004	GPI-linked ephrin receptor activity	4/3132	49/18639	0.0816326530612245	0.485808116349988	0.974508518156134	1
GO:0005008	hepatocyte growth factor receptor activity	4/3132	49/18639	0.0816326530612245	0.485808116349988	0.974508518156134	1
GO:0005009	insulin receptor activity	4/3132	49/18639	0.0816326530612245	0.485808116349988	0.974508518156134	1
GO:0005011	macrophage colony-stimulating factor receptor activity	4/3132	49/18639	0.0816326530612245	0.485808116349988	0.974508518156134	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	4/3132	49/18639	0.0816326530612245	0.485808116349988	0.974508518156134	1
GO:0005020	stem cell factor receptor activity	4/3132	49/18639	0.0816326530612245	0.485808116349988	0.974508518156134	1
GO:0008288	boss receptor activity	4/3132	49/18639	0.0816326530612245	0.485808116349988	0.974508518156134	1
GO:0036332	placental growth factor receptor activity	4/3132	49/18639	0.0816326530612245	0.485808116349988	0.974508518156134	1
GO:0038062	protein tyrosine kinase collagen receptor activity	4/3132	49/18639	0.0816326530612245	0.485808116349988	0.974508518156134	1
GO:0060175	brain-derived neurotrophic factor receptor activity	4/3132	49/18639	0.0816326530612245	0.485808116349988	0.974508518156134	1
GO:0001614	purinergic nucleotide receptor activity	1/3132	20/18639	0.05	0.297557471264368	0.974811127032997	1
GO:0015464	acetylcholine receptor activity	1/3132	20/18639	0.05	0.297557471264368	0.974811127032997	1
GO:0016502	nucleotide receptor activity	1/3132	20/18639	0.05	0.297557471264368	0.974811127032997	1
GO:0003730	mRNA 3'-UTR binding	33/3132	262/18639	0.125954198473282	0.749572255856804	0.97578729341061	1
GO:0005452	solute:inorganic anion antiporter activity	2/3132	31/18639	0.0645161290322581	0.383945124212087	0.9758564226473	1
GO:0072349	modified amino acid transmembrane transporter activity	2/3132	31/18639	0.0645161290322581	0.383945124212087	0.9758564226473	1
GO:0005539	glycosaminoglycan binding	30/3132	242/18639	0.12396694214876	0.737745796523226	0.976802733342823	1
GO:0042287	MHC protein binding	3/3132	41/18639	0.0731707317073171	0.435449957947855	0.977455688800251	1
GO:0005006	epidermal growth factor receptor activity	4/3132	50/18639	0.08	0.476091954022989	0.977602655893052	1
GO:0005007	fibroblast growth factor receptor activity	4/3132	50/18639	0.08	0.476091954022989	0.977602655893052	1
GO:0005017	platelet-derived growth factor receptor activity	4/3132	50/18639	0.08	0.476091954022989	0.977602655893052	1
GO:0005019	platelet-derived growth factor beta-receptor activity	4/3132	50/18639	0.08	0.476091954022989	0.977602655893052	1
GO:0016500	protein-hormone receptor activity	6/3132	67/18639	0.0895522388059701	0.532938754503345	0.977899787168333	1
GO:0031406	carboxylic acid binding	22/3132	187/18639	0.117647058823529	0.700135226504395	0.978431768036326	1
GO:0005248	voltage-gated sodium channel activity	1/3132	21/18639	0.0476190476190476	0.283388067870826	0.979048279948441	1
GO:0015174	basic amino acid transmembrane transporter activity	1/3132	21/18639	0.0476190476190476	0.283388067870826	0.979048279948441	1
GO:0036122	BMP binding	1/3132	21/18639	0.0476190476190476	0.283388067870826	0.979048279948441	1
GO:0061891	calcium ion sensor activity	1/3132	21/18639	0.0476190476190476	0.283388067870826	0.979048279948441	1
GO:0003777	microtubule motor activity	6/3132	68/18639	0.0882352941176471	0.525101419878296	0.980308684414542	1
GO:0005010	insulin-like growth factor receptor activity	4/3132	51/18639	0.0784313725490196	0.466756817669597	0.980340403082279	1
GO:0043177	organic acid binding	22/3132	189/18639	0.116402116402116	0.692726388128687	0.981388605421065	1
GO:0005243	gap junction channel activity	1/3132	22/18639	0.0454545454545455	0.270506792058516	0.982572868368329	1
GO:0033038	bitter taste receptor activity	1/3132	22/18639	0.0454545454545455	0.270506792058516	0.982572868368329	1
GO:0140784	metal ion sensor activity	1/3132	22/18639	0.0454545454545455	0.270506792058516	0.982572868368329	1
GO:0005245	voltage-gated calcium channel activity	3/3132	43/18639	0.0697674418604651	0.415196471531676	0.983022660719408	1
GO:1901681	sulfur compound binding	34/3132	275/18639	0.123636363636364	0.735778474399164	0.98348407977402	1
GO:0015085	calcium ion transmembrane transporter activity	16/3132	147/18639	0.108843537414966	0.647744155133318	0.983517617994091	1
GO:0019199	transmembrane receptor protein kinase activity	7/3132	78/18639	0.0897435897435897	0.534077512525788	0.983937674320965	1
GO:0008237	metallopeptidase activity	21/3132	184/18639	0.114130434782609	0.679207271364318	0.984209748505139	1
GO:0005544	calcium-dependent phospholipid binding	4/3132	53/18639	0.0754716981132075	0.449143352851876	0.984895151552579	1
GO:0008146	sulfotransferase activity	4/3132	53/18639	0.0754716981132075	0.449143352851876	0.984895151552579	1
GO:0017046	peptide hormone binding	4/3132	53/18639	0.0754716981132075	0.449143352851876	0.984895151552579	1
GO:0015020	glucuronosyltransferase activity	2/3132	34/18639	0.0588235294117647	0.350067613252197	0.984949378325008	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/3132	34/18639	0.0588235294117647	0.350067613252197	0.984949378325008	1
GO:0030547	signaling receptor inhibitor activity	3/3132	44/18639	0.0681818181818182	0.405760188087774	0.985286551332621	1
GO:0015179	L-amino acid transmembrane transporter activity	5/3132	62/18639	0.0806451612903226	0.479931405265109	0.985310484932936	1
GO:0003887	DNA-directed DNA polymerase activity	1/3132	23/18639	0.0434782608695652	0.258745627186407	0.985504692844367	1
GO:0005283	amino acid:sodium symporter activity	1/3132	23/18639	0.0434782608695652	0.258745627186407	0.985504692844367	1
GO:0016493	C-C chemokine receptor activity	1/3132	23/18639	0.0434782608695652	0.258745627186407	0.985504692844367	1
GO:0017134	fibroblast growth factor binding	1/3132	23/18639	0.0434782608695652	0.258745627186407	0.985504692844367	1
GO:0033293	monocarboxylic acid binding	7/3132	79/18639	0.0886075949367089	0.52731703768369	0.985645053289566	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	4/3132	54/18639	0.0740740740740741	0.440825883354619	0.98677772402287	1
GO:0004896	cytokine receptor activity	9/3132	96/18639	0.09375	0.55792025862069	0.986897209539111	1
GO:0005200	structural constituent of cytoskeleton	11/3132	112/18639	0.0982142857142857	0.58448788998358	0.987248581458099	1
GO:0042605	peptide antigen binding	3/3132	45/18639	0.0666666666666667	0.396743295019157	0.9872591586872	1
GO:0004806	triacylglycerol lipase activity	1/3132	24/18639	0.0416666666666667	0.247964559386973	0.987943417705317	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/3132	24/18639	0.0416666666666667	0.247964559386973	0.987943417705317	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/3132	24/18639	0.0416666666666667	0.247964559386973	0.987943417705317	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/3132	24/18639	0.0416666666666667	0.247964559386973	0.987943417705317	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/3132	36/18639	0.0555555555555556	0.330619412515964	0.989054380793205	1
GO:0042626	ATPase-coupled transmembrane transporter activity	9/3132	98/18639	0.0918367346938776	0.546534130893737	0.989390986405404	1
GO:0015271	outward rectifier potassium channel activity	1/3132	25/18639	0.04	0.238045977011494	0.989971954678024	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/3132	25/18639	0.04	0.238045977011494	0.989971954678024	1
GO:0099095	ligand-gated monoatomic anion channel activity	3/3132	47/18639	0.0638297872340425	0.379860601614087	0.990469054724037	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	8/3132	91/18639	0.0879120879120879	0.523177971453834	0.990608369306501	1
GO:0005262	calcium channel activity	13/3132	131/18639	0.099236641221374	0.590572080372028	0.990916348325488	1
GO:0001637	G protein-coupled chemoattractant receptor activity	1/3132	26/18639	0.0384615384615385	0.228890362511052	0.991659278087739	1
GO:0004435	phosphatidylinositol phospholipase C activity	1/3132	26/18639	0.0384615384615385	0.228890362511052	0.991659278087739	1
GO:0004950	chemokine receptor activity	1/3132	26/18639	0.0384615384615385	0.228890362511052	0.991659278087739	1
GO:0030247	polysaccharide binding	1/3132	26/18639	0.0384615384615385	0.228890362511052	0.991659278087739	1
GO:0000146	microfilament motor activity	2/3132	38/18639	0.0526315789473684	0.313218390804598	0.992059089380191	1
GO:0051015	actin filament binding	23/3132	209/18639	0.110047846889952	0.65491118077325	0.993038772382971	1
GO:0004364	glutathione transferase activity	1/3132	27/18639	0.037037037037037	0.220412941677309	0.993062767102363	1
GO:0015252	proton channel activity	1/3132	27/18639	0.037037037037037	0.220412941677309	0.993062767102363	1
GO:0005253	monoatomic anion channel activity	9/3132	103/18639	0.087378640776699	0.520003347840643	0.993821538972798	1
GO:0048020	CCR chemokine receptor binding	3/3132	50/18639	0.06	0.357068965517241	0.993867271585137	1
GO:0005242	inward rectifier potassium channel activity	1/3132	28/18639	0.0357142857142857	0.21254105090312	0.994230154456511	1
GO:0008527	taste receptor activity	1/3132	28/18639	0.0357142857142857	0.21254105090312	0.994230154456511	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	5/3132	70/18639	0.0714285714285714	0.42508210180624	0.994722047912415	1
GO:0017171	serine hydrolase activity	21/3132	198/18639	0.106060606060606	0.631182514803205	0.99488773257961	1
GO:0005416	amino acid:monoatomic cation symporter activity	1/3132	29/18639	0.0344827586206897	0.20521204914784	0.995201147753067	1
GO:0015101	organic cation transmembrane transporter activity	6/3132	81/18639	0.0740740740740741	0.440825883354619	0.995929115105875	1
GO:0008236	serine-type peptidase activity	20/3132	194/18639	0.103092783505155	0.613520559307975	0.996212753556801	1
GO:0001664	G protein-coupled receptor binding	34/3132	297/18639	0.114478114478114	0.681276365184411	0.99630882389567	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/3132	31/18639	0.032258064516129	0.191972562106044	0.996680523530566	1
GO:0004222	metalloendopeptidase activity	9/3132	110/18639	0.0818181818181818	0.486912225705329	0.997182850497463	1
GO:0015106	bicarbonate transmembrane transporter activity	1/3132	32/18639	0.03125	0.18597341954023	0.997239240227807	1
GO:0004252	serine-type endopeptidase activity	17/3132	176/18639	0.0965909090909091	0.574826933124347	0.997593021877264	1
GO:0042923	neuropeptide binding	1/3132	33/18639	0.0303030303030303	0.180337861372344	0.997703941663101	1
GO:0030414	peptidase inhibitor activity	16/3132	169/18639	0.0946745562130177	0.563422430796436	0.997774784418688	1
GO:0008083	growth factor activity	15/3132	162/18639	0.0925925925925926	0.551032354193274	0.997962603035528	1
GO:0019825	oxygen binding	1/3132	34/18639	0.0294117647058824	0.175033806626099	0.998090443582437	1
GO:0004497	monooxygenase activity	8/3132	106/18639	0.0754716981132075	0.449143352851876	0.998359645276421	1
GO:0005343	organic acid:sodium symporter activity	1/3132	35/18639	0.0285714285714286	0.170032840722496	0.998411901830209	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/3132	36/18639	0.0277777777777778	0.165309706257982	0.998679259574124	1
GO:0004620	phospholipase activity	8/3132	109/18639	0.073394495412844	0.436781609195402	0.998862034568927	1
GO:0061135	endopeptidase regulator activity	17/3132	184/18639	0.0923913043478261	0.549834457771114	0.998889463271198	1
GO:0022804	active transmembrane transporter activity	54/3132	457/18639	0.118161925601751	0.703199275635705	0.998934891422129	1
GO:0004866	endopeptidase inhibitor activity	14/3132	161/18639	0.0869565217391304	0.517491254372814	0.999010104479352	1
GO:0005254	chloride channel activity	5/3132	83/18639	0.0602409638554217	0.358502977426949	0.999089389952251	1
GO:0015171	amino acid transmembrane transporter activity	7/3132	102/18639	0.0686274509803922	0.408412215460897	0.999113296097941	1
GO:1901682	sulfur compound transmembrane transporter activity	3/3132	63/18639	0.0476190476190476	0.283388067870826	0.999147306866848	1
GO:0030246	carbohydrate binding	29/3132	280/18639	0.103571428571429	0.616369047619048	0.999206472567174	1
GO:0071855	neuropeptide receptor binding	1/3132	40/18639	0.025	0.148778735632184	0.999368271150146	1
GO:0004812	aminoacyl-tRNA ligase activity	1/3132	41/18639	0.024390243902439	0.145149985982618	0.999474651856514	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	1/3132	41/18639	0.024390243902439	0.145149985982618	0.999474651856514	1
GO:0170055	lipid transmembrane transporter activity	2/3132	56/18639	0.0357142857142857	0.21254105090312	0.999592318852115	1
GO:0016298	lipase activity	9/3132	130/18639	0.0692307692307692	0.412002652519894	0.999744029072989	1
GO:0008188	neuropeptide receptor activity	1/3132	48/18639	0.0208333333333333	0.123982279693487	0.999855545789061	1
GO:0005249	voltage-gated potassium channel activity	5/3132	98/18639	0.0510204081632653	0.303630072718743	0.999892580482058	1
GO:0005244	voltage-gated monoatomic ion channel activity	13/3132	173/18639	0.0751445086705202	0.447196199588067	0.999897476750514	1
GO:0005272	sodium channel activity	1/3132	51/18639	0.0196078431372549	0.116689204417399	0.999916947646203	1
GO:0022832	voltage-gated channel activity	13/3132	175/18639	0.0742857142857143	0.442085385878489	0.999918851903301	1
GO:0008509	monoatomic anion transmembrane transporter activity	10/3132	149/18639	0.0671140939597315	0.399406001697138	0.999926048523049	1
GO:0008514	organic anion transmembrane transporter activity	24/3132	269/18639	0.0892193308550186	0.530957569542366	0.999937730489055	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/3132	53/18639	0.0188679245283019	0.112285838212969	0.999942578292701	1
GO:0099094	ligand-gated monoatomic cation channel activity	8/3132	136/18639	0.0588235294117647	0.350067613252197	0.999965207726656	1
GO:0004867	serine-type endopeptidase inhibitor activity	4/3132	95/18639	0.0421052631578947	0.250574712643678	0.999966585761099	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/3132	56/18639	0.0178571428571429	0.10627052545156	0.999966991421805	1
GO:0046943	carboxylic acid transmembrane transporter activity	13/3132	188/18639	0.0691489361702128	0.411515651748594	0.999982881028649	1
GO:0005342	organic acid transmembrane transporter activity	13/3132	189/18639	0.0687830687830688	0.40933832025786	0.999984849715822	1
GO:0005125	cytokine activity	18/3132	234/18639	0.0769230769230769	0.457780725022104	0.999986777734392	1
GO:0005267	potassium channel activity	6/3132	124/18639	0.0483870967741935	0.287958843159066	0.999988885351018	1
GO:0022824	transmitter-gated monoatomic ion channel activity	1/3132	63/18639	0.0158730158730159	0.0944626892902755	0.999990934063602	1
GO:0022835	transmitter-gated channel activity	1/3132	63/18639	0.0158730158730159	0.0944626892902755	0.999990934063602	1
GO:0140375	immune receptor activity	9/3132	156/18639	0.0576923076923077	0.343335543766578	0.99999131919315	1
GO:0001653	peptide receptor activity	6/3132	128/18639	0.046875	0.278960129310345	0.999993815073315	1
GO:0015291	secondary active transmembrane transporter activity	23/3132	287/18639	0.0801393728222996	0.476921382514318	0.999995914629589	1
GO:0015108	chloride transmembrane transporter activity	5/3132	121/18639	0.0413223140495868	0.245915265507742	0.999996560537479	1
GO:0022843	voltage-gated monoatomic cation channel activity	7/3132	143/18639	0.048951048951049	0.291315006832248	0.999996777324753	1
GO:0098960	postsynaptic neurotransmitter receptor activity	1/3132	69/18639	0.0144927536231884	0.0862485423954689	0.999997006446137	1
GO:0015293	symporter activity	7/3132	146/18639	0.0479452054794521	0.285329082034325	0.999997911774995	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/3132	73/18639	0.0136986301369863	0.0815225948669501	0.999998570200514	1
GO:0015294	solute:monoatomic cation symporter activity	4/3132	116/18639	0.0344827586206897	0.20521204914784	0.999998778403689	1
GO:0015103	inorganic anion transmembrane transporter activity	8/3132	165/18639	0.0484848484848485	0.288540578195751	0.999999391271715	1
GO:0015370	solute:sodium symporter activity	1/3132	79/18639	0.0126582278481013	0.0753310053833843	0.999999528192526	1
GO:0008528	G protein-coupled peptide receptor activity	4/3132	122/18639	0.0327868852459016	0.19511965328811	0.999999534377303	1
GO:0022834	ligand-gated channel activity	10/3132	188/18639	0.0531914893617021	0.316550501345072	0.999999577236873	1
GO:0015079	potassium ion transmembrane transporter activity	7/3132	160/18639	0.04375	0.260362787356322	0.999999732881366	1
GO:0015276	ligand-gated monoatomic ion channel activity	9/3132	186/18639	0.0483870967741935	0.287958843159066	0.99999986662064	1
GO:0005261	monoatomic cation channel activity	25/3132	341/18639	0.0733137829912024	0.436301277513736	0.99999993417445	1
GO:0046873	metal ion transmembrane transporter activity	37/3132	450/18639	0.0822222222222222	0.489316730523627	0.999999971161551	1
GO:0030594	neurotransmitter receptor activity	1/3132	97/18639	0.0103092783505155	0.0613520559307975	0.999999983087517	1
GO:0015081	sodium ion transmembrane transporter activity	5/3132	164/18639	0.0304878048780488	0.181437482478273	0.999999996108703	1
GO:0022836	gated channel activity	19/3132	318/18639	0.059748427672956	0.355571821007735	0.99999999857215	1
GO:0005179	hormone activity	2/3132	132/18639	0.0151515151515152	0.0901689306861721	0.999999999278237	1
GO:0005216	monoatomic ion channel activity	32/3132	448/18639	0.0714285714285714	0.42508210180624	0.999999999676186	1
GO:0003823	antigen binding	3/3132	174/18639	0.0172413793103448	0.10260602457392	0.999999999992932	1
GO:0004984	olfactory receptor activity	1/3132	419/18639	0.00238663484486874	0.0142032205854114	1	1
GO:0030371	translation repressor activity	6/3132	329/18639	0.0182370820668693	0.108531600461168	1	1
GO:0045182	translation regulator activity	10/3132	356/18639	0.0280898876404494	0.167167118687847	1	1