ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0051082 unfolded protein binding 13/171 121/18639 0.107438016528926 11.7107438016529 8.56823983951472e-11 4.59257655397989e-08 GO:0140662 ATP-dependent protein folding chaperone 8/171 40/18639 0.2 21.8 2.55037916851111e-09 6.83501617160977e-07 GO:0044389 ubiquitin-like protein ligase binding 17/171 322/18639 0.0527950310559006 5.75465838509317 7.29819160923502e-09 1.30394356751666e-06 GO:0031625 ubiquitin protein ligase binding 16/171 302/18639 0.0529801324503311 5.77483443708609 1.96671474926799e-08 2.6353977640191e-06 GO:0044183 protein folding chaperone 9/171 75/18639 0.12 13.08 2.78631899158558e-08 2.98693395897974e-06 GO:0016209 antioxidant activity 7/171 86/18639 0.0813953488372093 8.87209302325581 1.41346393155945e-05 0.00126269444552644 GO:0003924 GTPase activity 12/171 331/18639 0.0362537764350453 3.95166163141994 5.69700679289303e-05 0.00436227948712952 GO:0031720 haptoglobin binding 3/171 10/18639 0.3 32.7 8.68393721838269e-05 0.00581823793631641 GO:0031072 heat shock protein binding 7/171 131/18639 0.0534351145038168 5.82442748091603 0.000207937808817776 0.0123838517251476 GO:0019825 oxygen binding 4/171 34/18639 0.117647058823529 12.8235294117647 0.00025585617280757 0.0124929612418809 GO:0005344 oxygen carrier activity 3/171 14/18639 0.214285714285714 23.3571428571429 0.00025638539862069 0.0124929612418809 GO:0140776 protein-containing complex destabilizing activity 3/171 15/18639 0.2 21.8 0.000318324825092772 0.0142185088541438 GO:0001664 G protein-coupled receptor binding 10/171 297/18639 0.0336700336700337 3.67003367003367 0.000428659889230856 0.0176739769713645 GO:0019003 GDP binding 5/171 75/18639 0.0666666666666667 7.26666666666667 0.000630026108128408 0.0241209995683448 GO:0030547 signaling receptor inhibitor activity 4/171 44/18639 0.0909090909090909 9.90909090909091 0.000697404304427998 0.0249205804782271 GO:0005525 GTP binding 11/171 378/18639 0.0291005291005291 3.17195767195767 0.000755318171055635 0.0253031587303638 GO:0019001 guanyl nucleotide binding 11/171 400/18639 0.0275 2.9975 0.00119402350128028 0.0354398714635743 GO:0032561 guanyl ribonucleotide binding 11/171 400/18639 0.0275 2.9975 0.00119402350128028 0.0354398714635743 GO:0043021 ribonucleoprotein complex binding 7/171 177/18639 0.0395480225988701 4.31073446327684 0.00125626410038789 0.0354398714635743 GO:0003925 G protein activity 4/171 54/18639 0.0740740740740741 8.07407407407407 0.00151321083485491 0.0405540503741116 GO:0004857 enzyme inhibitor activity 11/171 416/18639 0.0264423076923077 2.88221153846154 0.00163035688432401 0.0411524999540246 GO:0008198 ferrous iron binding 3/171 26/18639 0.115384615384615 12.5769230769231 0.00168909514736668 0.0411524999540246 GO:0004601 peroxidase activity 4/171 57/18639 0.0701754385964912 7.64912280701754 0.00185025092338315 0.0431188910840595 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/171 59/18639 0.0677966101694915 7.38983050847458 0.00210181900304035 0.0469406244012345 GO:0140416 transcription regulator inhibitor activity 3/171 33/18639 0.0909090909090909 9.90909090909091 0.00338187492901318 0.0686797114298533 GO:0032934 sterol binding 4/171 68/18639 0.0588235294117647 6.41176470588235 0.00352876766158921 0.0686797114298533 GO:0005522 profilin binding 2/171 10/18639 0.2 21.8 0.00358774611946995 0.0686797114298533 GO:0030957 Tat protein binding 2/171 10/18639 0.2 21.8 0.00358774611946995 0.0686797114298533 GO:0043022 ribosome binding 5/171 112/18639 0.0446428571428571 4.86607142857143 0.00373381530892484 0.0690112070890937 GO:0061631 ubiquitin conjugating enzyme activity 3/171 35/18639 0.0857142857142857 9.34285714285714 0.00400291577264027 0.0715187618045061 GO:0055106 ubiquitin-protein transferase regulator activity 3/171 36/18639 0.0833333333333333 9.08333333333333 0.00433769240281636 0.0730076833752321 GO:0010854 adenylate cyclase regulator activity 2/171 11/18639 0.181818181818182 19.8181818181818 0.00435866766419296 0.0730076833752321 GO:0004859 phospholipase inhibitor activity 2/171 12/18639 0.166666666666667 18.1666666666667 0.00519898787427703 0.0828253815391178 GO:0017022 myosin binding 4/171 76/18639 0.0526315789473684 5.73684210526316 0.00525384882897389 0.0828253815391178 GO:0061650 ubiquitin-like protein conjugating enzyme activity 3/171 41/18639 0.0731707317073171 7.97560975609756 0.0062633375585582 0.095918540896777 GO:0032036 myosin heavy chain binding 2/171 14/18639 0.142857142857143 15.5714285714286 0.00708255000242274 0.105451300036072 GO:0031386 protein tag activity 2/171 15/18639 0.133333333333333 14.5333333333333 0.00812320002970428 0.114579874103197 GO:0141047 molecular tag activity 2/171 15/18639 0.133333333333333 14.5333333333333 0.00812320002970428 0.114579874103197 GO:0005504 fatty acid binding 3/171 47/18639 0.0638297872340425 6.95744680851064 0.00915364773386239 0.117767680348129 GO:0008142 oxysterol binding 2/171 16/18639 0.125 13.625 0.00922806450489071 0.117767680348129 GO:0055102 lipase inhibitor activity 2/171 16/18639 0.125 13.625 0.00922806450489071 0.117767680348129 GO:0097027 ubiquitin-protein transferase activator activity 2/171 16/18639 0.125 13.625 0.00922806450489071 0.117767680348129 GO:0072341 modified amino acid binding 4/171 91/18639 0.043956043956044 4.79120879120879 0.00984836378685523 0.12113473876131 GO:0043178 alcohol binding 4/171 92/18639 0.0434782608695652 4.73913043478261 0.0102239979123106 0.12113473876131 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/171 17/18639 0.117647058823529 12.8235294117647 0.0103958917593662 0.12113473876131 GO:0036041 long-chain fatty acid binding 2/171 17/18639 0.117647058823529 12.8235294117647 0.0103958917593662 0.12113473876131 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/171 18/18639 0.111111111111111 12.1111111111111 0.0116254474514112 0.129817496540759 GO:0098641 cadherin binding involved in cell-cell adhesion 2/171 18/18639 0.111111111111111 12.1111111111111 0.0116254474514112 0.129817496540759 GO:0004864 protein phosphatase inhibitor activity 3/171 53/18639 0.0566037735849057 6.16981132075472 0.0127072427648277 0.131827279281556 GO:0005246 calcium channel regulator activity 3/171 53/18639 0.0566037735849057 6.16981132075472 0.0127072427648277 0.131827279281556 GO:0005520 insulin-like growth factor binding 2/171 19/18639 0.105263157894737 11.4736842105263 0.012915514356686 0.131827279281556 GO:0097001 ceramide binding 2/171 19/18639 0.105263157894737 11.4736842105263 0.012915514356686 0.131827279281556 GO:0015485 cholesterol binding 3/171 54/18639 0.0555555555555556 6.05555555555556 0.0133657152312967 0.131827279281556 GO:0051287 NAD binding 3/171 54/18639 0.0555555555555556 6.05555555555556 0.0133657152312967 0.131827279281556 GO:0005506 iron ion binding 5/171 154/18639 0.0324675324675325 3.53896103896104 0.0138652240293287 0.131827279281556 GO:0010851 cyclase regulator activity 2/171 20/18639 0.1 10.9 0.0142648921610639 0.131827279281556 GO:0016408 C-acyltransferase activity 2/171 20/18639 0.1 10.9 0.0142648921610639 0.131827279281556 GO:0043024 ribosomal small subunit binding 2/171 20/18639 0.1 10.9 0.0142648921610639 0.131827279281556 GO:0019212 phosphatase inhibitor activity 3/171 56/18639 0.0535714285714286 5.83928571428571 0.0147401630536834 0.133910633843632 GO:0001786 phosphatidylserine binding 3/171 59/18639 0.0508474576271186 5.54237288135593 0.0169465213616794 0.148150940624652 GO:0019888 protein phosphatase regulator activity 4/171 107/18639 0.0373831775700935 4.07476635514019 0.0170004182988676 0.148150940624652 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/171 22/18639 0.0909090909090909 9.90909090909091 0.017136862534941 0.148150940624652 GO:0005496 steroid binding 4/171 108/18639 0.037037037037037 4.03703703703704 0.0175314175271872 0.149156187215434 GO:0005212 structural constituent of eye lens 2/171 23/18639 0.0869565217391304 9.47826086956522 0.0186571371951597 0.156253524009463 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 6/171 229/18639 0.0262008733624454 2.85589519650655 0.019202202266856 0.158118115282302 GO:0016247 channel regulator activity 5/171 168/18639 0.0297619047619048 3.24404761904762 0.0194697679265521 0.158118115282302 GO:0048027 mRNA 5'-UTR binding 2/171 24/18639 0.0833333333333333 9.08333333333333 0.0202320865376419 0.158279403839591 GO:0060229 lipase activator activity 2/171 24/18639 0.0833333333333333 9.08333333333333 0.0202320865376419 0.158279403839591 GO:0141108 transporter regulator activity 5/171 170/18639 0.0294117647058824 3.20588235294118 0.0203755202703951 0.158279403839591 GO:0003735 structural constituent of ribosome 5/171 175/18639 0.0285714285714286 3.11428571428571 0.0227594007684751 0.171565965858047 GO:0019208 phosphatase regulator activity 4/171 117/18639 0.0341880341880342 3.72649572649573 0.0227776261175443 0.171565965858047 GO:0005160 transforming growth factor beta receptor binding 2/171 26/18639 0.0769230769230769 8.38461538461539 0.0235415498244322 0.171565965858047 GO:0050750 low-density lipoprotein particle receptor binding 2/171 26/18639 0.0769230769230769 8.38461538461539 0.0235415498244322 0.171565965858047 GO:0050840 extracellular matrix binding 3/171 67/18639 0.0447761194029851 4.88059701492537 0.0236863460326408 0.171565965858047 GO:0015631 tubulin binding 8/171 385/18639 0.0207792207792208 2.26493506493506 0.0259550409302928 0.183815115453333 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/171 122/18639 0.0327868852459016 3.57377049180328 0.0260633372657712 0.183815115453333 GO:0033218 amide binding 6/171 247/18639 0.0242914979757085 2.64777327935223 0.0266127394234583 0.185252315986671 GO:0046625 sphingolipid binding 2/171 28/18639 0.0714285714285714 7.78571428571429 0.0270564895109719 0.185926645870268 GO:0005518 collagen binding 3/171 72/18639 0.0416666666666667 4.54166666666667 0.0285331146274561 0.193551890460568 GO:0003785 actin monomer binding 2/171 29/18639 0.0689655172413793 7.51724137931034 0.0288883418597863 0.193551890460568 GO:0043539 protein serine/threonine kinase activator activity 3/171 73/18639 0.0410958904109589 4.47945205479452 0.029560853793573 0.193612528849943 GO:0042826 histone deacetylase binding 4/171 127/18639 0.031496062992126 3.43307086614173 0.0296198271748048 0.193612528849943 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 4/171 128/18639 0.03125 3.40625 0.0303639202543674 0.196085075377602 GO:0048019 receptor antagonist activity 2/171 30/18639 0.0666666666666667 7.26666666666667 0.0307683880825738 0.196331619193566 GO:0070273 phosphatidylinositol-4-phosphate binding 2/171 31/18639 0.0645161290322581 7.03225806451613 0.0326956008521569 0.198756815514708 GO:0070325 lipoprotein particle receptor binding 2/171 31/18639 0.0645161290322581 7.03225806451613 0.0326956008521569 0.198756815514708 GO:0098631 cell adhesion mediator activity 3/171 76/18639 0.0394736842105263 4.30263157894737 0.0327602357195195 0.198756815514708 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/171 132/18639 0.0303030303030303 3.3030303030303 0.0334503186538802 0.198756815514708 GO:0045296 cadherin binding 7/171 334/18639 0.0209580838323353 2.28443113772455 0.0347223484857997 0.198756815514708 GO:0051087 protein-folding chaperone binding 4/171 134/18639 0.0298507462686567 3.25373134328358 0.0350597638134646 0.198756815514708 GO:0033293 monocarboxylic acid binding 3/171 79/18639 0.0379746835443038 4.13924050632911 0.0361328710657163 0.198756815514708 GO:0071889 14-3-3 protein binding 2/171 33/18639 0.0606060606060606 6.60606060606061 0.0366874895375043 0.198756815514708 GO:0002020 protease binding 4/171 136/18639 0.0294117647058824 3.20588235294118 0.0367135105543125 0.198756815514708 GO:0044325 transmembrane transporter binding 4/171 136/18639 0.0294117647058824 3.20588235294118 0.0367135105543125 0.198756815514708 GO:0048306 calcium-dependent protein binding 3/171 80/18639 0.0375 4.0875 0.0372953233850848 0.198756815514708 GO:0033192 calmodulin-dependent protein phosphatase activity 3/171 81/18639 0.037037037037037 4.03703703703704 0.0384767895950241 0.198756815514708 GO:0140791 histone H2AXS140 phosphatase activity 3/171 81/18639 0.037037037037037 4.03703703703704 0.0384767895950241 0.198756815514708 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 3/171 81/18639 0.037037037037037 4.03703703703704 0.0384767895950241 0.198756815514708 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 3/171 81/18639 0.037037037037037 4.03703703703704 0.0384767895950241 0.198756815514708 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 3/171 81/18639 0.037037037037037 4.03703703703704 0.0384767895950241 0.198756815514708 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 3/171 81/18639 0.037037037037037 4.03703703703704 0.0384767895950241 0.198756815514708 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 3/171 81/18639 0.037037037037037 4.03703703703704 0.0384767895950241 0.198756815514708 GO:1990439 MAP kinase serine/threonine phosphatase activity 3/171 81/18639 0.037037037037037 4.03703703703704 0.0384767895950241 0.198756815514708 GO:0016887 ATP hydrolysis activity 8/171 417/18639 0.0191846522781775 2.09112709832134 0.0388323515136466 0.198756815514708 GO:0030295 protein kinase activator activity 4/171 139/18639 0.0287769784172662 3.13669064748201 0.0392773472647613 0.198756815514708 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 3/171 82/18639 0.0365853658536585 3.98780487804878 0.039677200112078 0.198756815514708 GO:0033549 MAP kinase phosphatase activity 3/171 82/18639 0.0365853658536585 3.98780487804878 0.039677200112078 0.198756815514708 GO:0000175 3'-5'-RNA exonuclease activity 2/171 35/18639 0.0571428571428571 6.22857142857143 0.0408560780672915 0.201105634595095 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 3/171 83/18639 0.036144578313253 3.93975903614458 0.0408964816620622 0.201105634595095 GO:0017018 myosin phosphatase activity 3/171 84/18639 0.0357142857142857 3.89285714285714 0.0421345573826118 0.205310206882545 GO:0016409 palmitoyltransferase activity 2/171 36/18639 0.0555555555555556 6.05555555555556 0.0430042184004959 0.20580590234523 GO:0045505 dynein intermediate chain binding 2/171 36/18639 0.0555555555555556 6.05555555555556 0.0430042184004959 0.20580590234523 GO:0019903 protein phosphatase binding 4/171 144/18639 0.0277777777777778 3.02777777777778 0.0437725926199101 0.207629288887361 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/171 38/18639 0.0526315789473684 5.73684210526316 0.0474234791487833 0.22171140710925 GO:0019209 kinase activator activity 4/171 148/18639 0.027027027027027 2.94594594594595 0.0475686787641114 0.22171140710925 GO:0004532 RNA exonuclease activity 2/171 40/18639 0.05 5.45 0.0520005879752107 0.232269292955941 GO:0015036 disulfide oxidoreductase activity 2/171 40/18639 0.05 5.45 0.0520005879752107 0.232269292955941 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/171 40/18639 0.05 5.45 0.0520005879752107 0.232269292955941 GO:0061791 GTPase motor activity 2/171 40/18639 0.05 5.45 0.0520005879752107 0.232269292955941 GO:1990606 membrane scission GTPase motor activity 2/171 40/18639 0.05 5.45 0.0520005879752107 0.232269292955941 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/171 41/18639 0.0487804878048781 5.31707317073171 0.0543460879965775 0.240739695588145 GO:0048487 beta-tubulin binding 2/171 42/18639 0.0476190476190476 5.19047619047619 0.0567283791241779 0.2472065952078 GO:0051879 Hsp90 protein binding 2/171 42/18639 0.0476190476190476 5.19047619047619 0.0567283791241779 0.2472065952078 GO:0099106 ion channel regulator activity 4/171 160/18639 0.025 2.725 0.060016652824456 0.257949552939277 GO:0000287 magnesium ion binding 5/171 230/18639 0.0217391304347826 2.3695652173913 0.0610868065144635 0.257949552939277 GO:0005178 integrin binding 4/171 161/18639 0.0248447204968944 2.70807453416149 0.0611251167990136 0.257949552939277 GO:0001046 core promoter sequence-specific DNA binding 2/171 44/18639 0.0454545454545455 4.95454545454546 0.0615998932392304 0.257949552939277 GO:0003954 NADH dehydrogenase activity 2/171 44/18639 0.0454545454545455 4.95454545454546 0.0615998932392304 0.257949552939277 GO:0043130 ubiquitin binding 3/171 100/18639 0.03 3.27 0.0644246433157693 0.26768689005622 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/171 46/18639 0.0434782608695652 4.73913043478261 0.0666083722865176 0.274631442658257 GO:0004722 protein serine/threonine phosphatase activity 3/171 103/18639 0.029126213592233 3.1747572815534 0.0691036299008204 0.280938100875857 GO:0005201 extracellular matrix structural constituent 4/171 168/18639 0.0238095238095238 2.5952380952381 0.0691862487231589 0.280938100875857 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/171 48/18639 0.0416666666666667 4.54166666666667 0.0717472545931247 0.289146830540713 GO:0060590 ATPase regulator activity 2/171 49/18639 0.0408163265306122 4.44897959183673 0.0743635989426919 0.297454395770768 GO:0140104 molecular carrier activity 5/171 249/18639 0.0200803212851406 2.18875502008032 0.0796867779366243 0.311390137835875 GO:0005200 structural constituent of cytoskeleton 3/171 112/18639 0.0267857142857143 2.91964285714286 0.0840249017370034 0.311390137835875 GO:0005544 calcium-dependent phospholipid binding 2/171 53/18639 0.0377358490566038 4.11320754716981 0.0851236289292813 0.311390137835875 GO:0019887 protein kinase regulator activity 5/171 255/18639 0.0196078431372549 2.13725490196078 0.0861264130160722 0.311390137835875 GO:0005543 phospholipid binding 8/171 497/18639 0.0160965794768612 1.75452716297787 0.0878118435539534 0.311390137835875 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/171 54/18639 0.037037037037037 4.03703703703704 0.087883548686896 0.311390137835875 GO:0005528 FK506 binding 1/171 10/18639 0.1 10.9 0.0880671429232631 0.311390137835875 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/171 10/18639 0.1 10.9 0.0880671429232631 0.311390137835875 GO:0031996 thioesterase binding 1/171 10/18639 0.1 10.9 0.0880671429232631 0.311390137835875 GO:1905394 retromer complex binding 1/171 10/18639 0.1 10.9 0.0880671429232631 0.311390137835875 GO:1990757 ubiquitin ligase activator activity 1/171 10/18639 0.1 10.9 0.0880671429232631 0.311390137835875 GO:0098632 cell-cell adhesion mediator activity 2/171 55/18639 0.0363636363636364 3.96363636363636 0.0906699719454954 0.311390137835875 GO:0140313 molecular sequestering activity 2/171 55/18639 0.0363636363636364 3.96363636363636 0.0906699719454954 0.311390137835875 GO:0015078 proton transmembrane transporter activity 4/171 185/18639 0.0216216216216216 2.35675675675676 0.0909037311043147 0.311390137835875 GO:0009055 electron transfer activity 3/171 116/18639 0.0258620689655172 2.81896551724138 0.0910631921037225 0.311390137835875 GO:0031406 carboxylic acid binding 4/171 187/18639 0.0213903743315508 2.33155080213904 0.093651250348477 0.311390137835875 GO:0022853 active monoatomic ion transmembrane transporter activity 3/171 118/18639 0.0254237288135593 2.77118644067797 0.0946718385554088 0.311390137835875 GO:0043177 organic acid binding 4/171 189/18639 0.0211640211640212 2.30687830687831 0.0964379580433979 0.311390137835875 GO:0005114 type II transforming growth factor beta receptor binding 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:0008199 ferric iron binding 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:0008526 phosphatidylinositol transfer activity 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:0019107 myristoyltransferase activity 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:0019215 intermediate filament binding 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:0034713 type I transforming growth factor beta receptor binding 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:0050786 RAGE receptor binding 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:0070697 activin receptor binding 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:0070990 snRNP binding 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:0097493 structural molecule activity conferring elasticity 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:1990948 ubiquitin ligase inhibitor activity 1/171 11/18639 0.0909090909090909 9.90909090909091 0.0964379904491703 0.311390137835875 GO:0019902 phosphatase binding 4/171 190/18639 0.0210526315789474 2.29473684210526 0.097845876255408 0.312712489025701 GO:0032182 ubiquitin-like protein binding 3/171 120/18639 0.025 2.725 0.0983385600578196 0.312712489025701 GO:0008408 3'-5' exonuclease activity 2/171 58/18639 0.0344827586206897 3.75862068965517 0.0991811998775544 0.312712489025701 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/171 58/18639 0.0344827586206897 3.75862068965517 0.0991811998775544 0.312712489025701 GO:0003720 telomerase activity 1/171 12/18639 0.0833333333333333 9.08333333333333 0.104732445228706 0.319696912134373 GO:0005527 macrolide binding 1/171 12/18639 0.0833333333333333 9.08333333333333 0.104732445228706 0.319696912134373 GO:0008179 adenylate cyclase binding 1/171 12/18639 0.0833333333333333 9.08333333333333 0.104732445228706 0.319696912134373 GO:0010853 cyclase activator activity 1/171 12/18639 0.0833333333333333 9.08333333333333 0.104732445228706 0.319696912134373 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/171 12/18639 0.0833333333333333 9.08333333333333 0.104732445228706 0.319696912134373 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/171 60/18639 0.0333333333333333 3.63333333333333 0.104975105476958 0.319696912134373 GO:0008017 microtubule binding 5/171 276/18639 0.0181159420289855 1.97463768115942 0.110727057001766 0.325493781688037 GO:0003964 RNA-directed DNA polymerase activity 1/171 13/18639 0.0769230769230769 8.38461538461539 0.112951200361894 0.325493781688037 GO:0005542 folic acid binding 1/171 13/18639 0.0769230769230769 8.38461538461539 0.112951200361894 0.325493781688037 GO:0019855 calcium channel inhibitor activity 1/171 13/18639 0.0769230769230769 8.38461538461539 0.112951200361894 0.325493781688037 GO:0031432 titin binding 1/171 13/18639 0.0769230769230769 8.38461538461539 0.112951200361894 0.325493781688037 GO:0031994 insulin-like growth factor I binding 1/171 13/18639 0.0769230769230769 8.38461538461539 0.112951200361894 0.325493781688037 GO:0035325 Toll-like receptor binding 1/171 13/18639 0.0769230769230769 8.38461538461539 0.112951200361894 0.325493781688037 GO:0039706 co-receptor binding 1/171 13/18639 0.0769230769230769 8.38461538461539 0.112951200361894 0.325493781688037 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/171 13/18639 0.0769230769230769 8.38461538461539 0.112951200361894 0.325493781688037 GO:0089720 caspase binding 1/171 13/18639 0.0769230769230769 8.38461538461539 0.112951200361894 0.325493781688037 GO:0003714 transcription corepressor activity 4/171 204/18639 0.0196078431372549 2.13725490196078 0.118542930892282 0.339780807263441 GO:0019843 rRNA binding 2/171 65/18639 0.0307692307692308 3.35384615384615 0.119840527210333 0.339826645474971 GO:0120013 lipid transfer activity 2/171 65/18639 0.0307692307692308 3.35384615384615 0.119840527210333 0.339826645474971 GO:0016530 metallochaperone activity 1/171 14/18639 0.0714285714285714 7.78571428571429 0.121094942697238 0.339826645474971 GO:0019992 diacylglycerol binding 1/171 14/18639 0.0714285714285714 7.78571428571429 0.121094942697238 0.339826645474971 GO:0019207 kinase regulator activity 5/171 287/18639 0.0174216027874564 1.89895470383275 0.12483768846247 0.342234910473165 GO:0051015 actin filament binding 4/171 209/18639 0.0191387559808612 2.08612440191388 0.126362000662868 0.342234910473165 GO:0005548 phospholipid transporter activity 2/171 68/18639 0.0294117647058824 3.20588235294118 0.128995701074633 0.342234910473165 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 2/171 68/18639 0.0294117647058824 3.20588235294118 0.128995701074633 0.342234910473165 GO:0000774 adenyl-nucleotide exchange factor activity 1/171 15/18639 0.0666666666666667 7.26666666666667 0.129164352887776 0.342234910473165 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/171 15/18639 0.0666666666666667 7.26666666666667 0.129164352887776 0.342234910473165 GO:0008242 omega peptidase activity 1/171 15/18639 0.0666666666666667 7.26666666666667 0.129164352887776 0.342234910473165 GO:0050700 CARD domain binding 1/171 15/18639 0.0666666666666667 7.26666666666667 0.129164352887776 0.342234910473165 GO:0051371 muscle alpha-actinin binding 1/171 15/18639 0.0666666666666667 7.26666666666667 0.129164352887776 0.342234910473165 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/171 15/18639 0.0666666666666667 7.26666666666667 0.129164352887776 0.342234910473165 GO:0019838 growth factor binding 3/171 136/18639 0.0220588235294118 2.40441176470588 0.129615087362038 0.342234910473165 GO:0140789 histone phosphatase activity 3/171 136/18639 0.0220588235294118 2.40441176470588 0.129615087362038 0.342234910473165 GO:0000062 fatty-acyl-CoA binding 1/171 16/18639 0.0625 6.8125 0.137160105446635 0.348425670708039 GO:0008296 3'-5'-DNA exonuclease activity 1/171 16/18639 0.0625 6.8125 0.137160105446635 0.348425670708039 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/171 16/18639 0.0625 6.8125 0.137160105446635 0.348425670708039 GO:0016722 oxidoreductase activity, acting on metal ions 1/171 16/18639 0.0625 6.8125 0.137160105446635 0.348425670708039 GO:0019841 retinol binding 1/171 16/18639 0.0625 6.8125 0.137160105446635 0.348425670708039 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/171 16/18639 0.0625 6.8125 0.137160105446635 0.348425670708039 GO:0043023 ribosomal large subunit binding 1/171 16/18639 0.0625 6.8125 0.137160105446635 0.348425670708039 GO:0070411 I-SMAD binding 1/171 16/18639 0.0625 6.8125 0.137160105446635 0.348425670708039 GO:0020037 heme binding 3/171 142/18639 0.0211267605633803 2.30281690140845 0.14215102324718 0.353474625808726 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/171 17/18639 0.0588235294117647 6.41176470588235 0.145082868802089 0.353474625808726 GO:0008429 phosphatidylethanolamine binding 1/171 17/18639 0.0588235294117647 6.41176470588235 0.145082868802089 0.353474625808726 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/171 17/18639 0.0588235294117647 6.41176470588235 0.145082868802089 0.353474625808726 GO:0031489 myosin V binding 1/171 17/18639 0.0588235294117647 6.41176470588235 0.145082868802089 0.353474625808726 GO:0045236 CXCR chemokine receptor binding 1/171 17/18639 0.0588235294117647 6.41176470588235 0.145082868802089 0.353474625808726 GO:0051787 misfolded protein binding 1/171 17/18639 0.0588235294117647 6.41176470588235 0.145082868802089 0.353474625808726 GO:0070492 oligosaccharide binding 1/171 17/18639 0.0588235294117647 6.41176470588235 0.145082868802089 0.353474625808726 GO:1901567 fatty acid derivative binding 1/171 17/18639 0.0588235294117647 6.41176470588235 0.145082868802089 0.353474625808726 GO:0003746 translation elongation factor activity 1/171 18/18639 0.0555555555555556 6.05555555555556 0.152933305352129 0.359527419599742 GO:0004706 JUN kinase kinase kinase activity 1/171 18/18639 0.0555555555555556 6.05555555555556 0.152933305352129 0.359527419599742 GO:0008308 voltage-gated monoatomic anion channel activity 1/171 18/18639 0.0555555555555556 6.05555555555556 0.152933305352129 0.359527419599742 GO:0008525 phosphatidylcholine transporter activity 1/171 18/18639 0.0555555555555556 6.05555555555556 0.152933305352129 0.359527419599742 GO:0031690 adrenergic receptor binding 1/171 18/18639 0.0555555555555556 6.05555555555556 0.152933305352129 0.359527419599742 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/171 18/18639 0.0555555555555556 6.05555555555556 0.152933305352129 0.359527419599742 GO:0070064 proline-rich region binding 1/171 18/18639 0.0555555555555556 6.05555555555556 0.152933305352129 0.359527419599742 GO:1990381 ubiquitin-specific protease binding 1/171 18/18639 0.0555555555555556 6.05555555555556 0.152933305352129 0.359527419599742 GO:0016918 retinal binding 1/171 19/18639 0.0526315789473684 5.73684210526316 0.160712071518543 0.374529001451908 GO:0120227 acyl-CoA binding 1/171 19/18639 0.0526315789473684 5.73684210526316 0.160712071518543 0.374529001451908 GO:0046906 tetrapyrrole binding 3/171 152/18639 0.0197368421052632 2.15131578947368 0.163886480163523 0.380273391201941 GO:0001614 purinergic nucleotide receptor activity 1/171 20/18639 0.05 5.45 0.168419817800515 0.380898828443359 GO:0016004 phospholipase activator activity 1/171 20/18639 0.05 5.45 0.168419817800515 0.380898828443359 GO:0016502 nucleotide receptor activity 1/171 20/18639 0.05 5.45 0.168419817800515 0.380898828443359 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/171 20/18639 0.05 5.45 0.168419817800515 0.380898828443359 GO:0030742 GTP-dependent protein binding 1/171 20/18639 0.05 5.45 0.168419817800515 0.380898828443359 GO:0052745 inositol phosphate phosphatase activity 1/171 20/18639 0.05 5.45 0.168419817800515 0.380898828443359 GO:0001618 virus receptor activity 2/171 81/18639 0.0246913580246914 2.69135802469136 0.170294649805002 0.383073219769791 GO:0003712 transcription coregulator activity 7/171 495/18639 0.0141414141414141 1.54141414141414 0.170810633442127 0.383073219769791 GO:0140272 exogenous protein binding 2/171 82/18639 0.024390243902439 2.65853658536585 0.173560086047326 0.385170013108877 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/171 21/18639 0.0476190476190476 5.19047619047619 0.176057188827751 0.385170013108877 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/171 21/18639 0.0476190476190476 5.19047619047619 0.176057188827751 0.385170013108877 GO:0010314 phosphatidylinositol-5-phosphate binding 1/171 21/18639 0.0476190476190476 5.19047619047619 0.176057188827751 0.385170013108877 GO:0070182 DNA polymerase binding 1/171 21/18639 0.0476190476190476 5.19047619047619 0.176057188827751 0.385170013108877 GO:0072542 protein phosphatase activator activity 1/171 21/18639 0.0476190476190476 5.19047619047619 0.176057188827751 0.385170013108877 GO:0008135 translation factor activity, RNA binding 2/171 83/18639 0.0240963855421687 2.62650602409639 0.176835730600048 0.385300616266771 GO:0004527 exonuclease activity 2/171 84/18639 0.0238095238095238 2.5952380952381 0.180121125068766 0.387730614605858 GO:0051117 ATPase binding 2/171 84/18639 0.0238095238095238 2.5952380952381 0.180121125068766 0.387730614605858 GO:0180051 translation factor activity 2/171 84/18639 0.0238095238095238 2.5952380952381 0.180121125068766 0.387730614605858 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/171 22/18639 0.0454545454545455 4.95454545454546 0.183624823413123 0.392123128882207 GO:0070034 telomerase RNA binding 1/171 22/18639 0.0454545454545455 4.95454545454546 0.183624823413123 0.392123128882207 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/171 23/18639 0.0434782608695652 4.73913043478261 0.191123354604849 0.39416528748029 GO:0004602 glutathione peroxidase activity 1/171 23/18639 0.0434782608695652 4.73913043478261 0.191123354604849 0.39416528748029 GO:0008171 O-methyltransferase activity 1/171 23/18639 0.0434782608695652 4.73913043478261 0.191123354604849 0.39416528748029 GO:0031681 G-protein beta-subunit binding 1/171 23/18639 0.0434782608695652 4.73913043478261 0.191123354604849 0.39416528748029 GO:0042171 lysophosphatidic acid acyltransferase activity 1/171 23/18639 0.0434782608695652 4.73913043478261 0.191123354604849 0.39416528748029 GO:0071617 lysophospholipid acyltransferase activity 1/171 23/18639 0.0434782608695652 4.73913043478261 0.191123354604849 0.39416528748029 GO:0099186 structural constituent of postsynapse 1/171 23/18639 0.0434782608695652 4.73913043478261 0.191123354604849 0.39416528748029 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/171 23/18639 0.0434782608695652 4.73913043478261 0.191123354604849 0.39416528748029 GO:0004197 cysteine-type endopeptidase activity 2/171 88/18639 0.0227272727272727 2.47727272727273 0.193351293251939 0.39416528748029 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/171 88/18639 0.0227272727272727 2.47727272727273 0.193351293251939 0.39416528748029 GO:0015399 primary active transmembrane transporter activity 3/171 166/18639 0.0180722891566265 1.96987951807229 0.195817899598158 0.39416528748029 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/171 89/18639 0.0224719101123595 2.44943820224719 0.196678819079973 0.39416528748029 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/171 89/18639 0.0224719101123595 2.44943820224719 0.196678819079973 0.39416528748029 GO:0019957 C-C chemokine binding 1/171 24/18639 0.0416666666666667 4.54166666666667 0.198553409738206 0.39416528748029 GO:0035035 histone acetyltransferase binding 1/171 24/18639 0.0416666666666667 4.54166666666667 0.198553409738206 0.39416528748029 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/171 24/18639 0.0416666666666667 4.54166666666667 0.198553409738206 0.39416528748029 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/171 24/18639 0.0416666666666667 4.54166666666667 0.198553409738206 0.39416528748029 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/171 24/18639 0.0416666666666667 4.54166666666667 0.198553409738206 0.39416528748029 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/171 24/18639 0.0416666666666667 4.54166666666667 0.198553409738206 0.39416528748029 GO:0140793 histone H2AXY142 phosphatase activity 2/171 90/18639 0.0222222222222222 2.42222222222222 0.200013497743175 0.395598652362885 GO:0004709 MAP kinase kinase kinase activity 1/171 25/18639 0.04 4.36 0.205915610486783 0.398450423180201 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/171 25/18639 0.04 4.36 0.205915610486783 0.398450423180201 GO:0019211 phosphatase activator activity 1/171 25/18639 0.04 4.36 0.205915610486783 0.398450423180201 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/171 25/18639 0.04 4.36 0.205915610486783 0.398450423180201 GO:0019707 protein-cysteine S-acyltransferase activity 1/171 25/18639 0.04 4.36 0.205915610486783 0.398450423180201 GO:0120020 cholesterol transfer activity 1/171 25/18639 0.04 4.36 0.205915610486783 0.398450423180201 GO:0052689 carboxylic ester hydrolase activity 2/171 92/18639 0.0217391304347826 2.3695652173913 0.206702687668413 0.398534678382263 GO:0004529 DNA exonuclease activity 1/171 26/18639 0.0384615384615385 4.19230769230769 0.213210572913277 0.40137124138063 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/171 26/18639 0.0384615384615385 4.19230769230769 0.213210572913277 0.40137124138063 GO:0019865 immunoglobulin binding 1/171 26/18639 0.0384615384615385 4.19230769230769 0.213210572913277 0.40137124138063 GO:0097602 cullin family protein binding 1/171 26/18639 0.0384615384615385 4.19230769230769 0.213210572913277 0.40137124138063 GO:0120014 phospholipid transfer activity 1/171 26/18639 0.0384615384615385 4.19230769230769 0.213210572913277 0.40137124138063 GO:0016410 N-acyltransferase activity 2/171 94/18639 0.0212765957446809 2.31914893617021 0.213415678719178 0.40137124138063 GO:0042562 hormone binding 2/171 94/18639 0.0212765957446809 2.31914893617021 0.213415678719178 0.40137124138063 GO:0004721 phosphoprotein phosphatase activity 3/171 175/18639 0.0171428571428571 1.86857142857143 0.217093529278965 0.402621298824078 GO:0004252 serine-type endopeptidase activity 3/171 176/18639 0.0170454545454545 1.85795454545455 0.219487598974693 0.402621298824078 GO:0004896 cytokine receptor activity 2/171 96/18639 0.0208333333333333 2.27083333333333 0.220149392619284 0.402621298824078 GO:0001671 ATPase activator activity 1/171 27/18639 0.037037037037037 4.03703703703704 0.220438907519834 0.402621298824078 GO:0004364 glutathione transferase activity 1/171 27/18639 0.037037037037037 4.03703703703704 0.220438907519834 0.402621298824078 GO:0008320 protein transmembrane transporter activity 1/171 27/18639 0.037037037037037 4.03703703703704 0.220438907519834 0.402621298824078 GO:0023026 MHC class II protein complex binding 1/171 27/18639 0.037037037037037 4.03703703703704 0.220438907519834 0.402621298824078 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/171 27/18639 0.037037037037037 4.03703703703704 0.220438907519834 0.402621298824078 GO:0003779 actin binding 6/171 443/18639 0.0135440180586907 1.47629796839729 0.222471404738014 0.402621298824078 GO:0005319 lipid transporter activity 3/171 178/18639 0.0168539325842697 1.83707865168539 0.224292043572346 0.402621298824078 GO:0004725 protein tyrosine phosphatase activity 2/171 98/18639 0.0204081632653061 2.22448979591837 0.226900854352224 0.402621298824078 GO:0019789 SUMO transferase activity 1/171 28/18639 0.0357142857142857 3.89285714285714 0.227601219297939 0.402621298824078 GO:0050698 proteoglycan sulfotransferase activity 1/171 28/18639 0.0357142857142857 3.89285714285714 0.227601219297939 0.402621298824078 GO:0051019 mitogen-activated protein kinase binding 1/171 28/18639 0.0357142857142857 3.89285714285714 0.227601219297939 0.402621298824078 GO:0051393 alpha-actinin binding 1/171 28/18639 0.0357142857142857 3.89285714285714 0.227601219297939 0.402621298824078 GO:0051537 2 iron, 2 sulfur cluster binding 1/171 28/18639 0.0357142857142857 3.89285714285714 0.227601219297939 0.402621298824078 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/171 28/18639 0.0357142857142857 3.89285714285714 0.227601219297939 0.402621298824078 GO:0097718 disordered domain specific binding 1/171 28/18639 0.0357142857142857 3.89285714285714 0.227601219297939 0.402621298824078 GO:0016417 S-acyltransferase activity 1/171 29/18639 0.0344827586206897 3.75862068965517 0.234698107777873 0.412453068094886 GO:0043236 laminin binding 1/171 29/18639 0.0344827586206897 3.75862068965517 0.234698107777873 0.412453068094886 GO:1901981 phosphatidylinositol phosphate binding 3/171 185/18639 0.0162162162162162 1.76756756756757 0.241263758964244 0.413953257359914 GO:0001965 G-protein alpha-subunit binding 1/171 30/18639 0.0333333333333333 3.63333333333333 0.241730167077711 0.413953257359914 GO:0001968 fibronectin binding 1/171 30/18639 0.0333333333333333 3.63333333333333 0.241730167077711 0.413953257359914 GO:0031210 phosphatidylcholine binding 1/171 30/18639 0.0333333333333333 3.63333333333333 0.241730167077711 0.413953257359914 GO:0033612 receptor serine/threonine kinase binding 1/171 30/18639 0.0333333333333333 3.63333333333333 0.241730167077711 0.413953257359914 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/171 30/18639 0.0333333333333333 3.63333333333333 0.241730167077711 0.413953257359914 GO:0051721 protein phosphatase 2A binding 1/171 30/18639 0.0333333333333333 3.63333333333333 0.241730167077711 0.413953257359914 GO:0098918 structural constituent of synapse 1/171 30/18639 0.0333333333333333 3.63333333333333 0.241730167077711 0.413953257359914 GO:0016411 acylglycerol O-acyltransferase activity 1/171 31/18639 0.032258064516129 3.51612903225806 0.248697985951896 0.424529046083492 GO:0022884 macromolecule transmembrane transporter activity 1/171 32/18639 0.03125 3.40625 0.255602147839377 0.429475709222275 GO:0030515 snoRNA binding 1/171 32/18639 0.03125 3.40625 0.255602147839377 0.429475709222275 GO:0043425 bHLH transcription factor binding 1/171 32/18639 0.03125 3.40625 0.255602147839377 0.429475709222275 GO:0051059 NF-kappaB binding 1/171 32/18639 0.03125 3.40625 0.255602147839377 0.429475709222275 GO:0120015 sterol transfer activity 1/171 32/18639 0.03125 3.40625 0.255602147839377 0.429475709222275 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/171 33/18639 0.0303030303030303 3.3030303030303 0.26244323091131 0.435509510119078 GO:0019956 chemokine binding 1/171 33/18639 0.0303030303030303 3.3030303030303 0.26244323091131 0.435509510119078 GO:0030296 protein tyrosine kinase activator activity 1/171 33/18639 0.0303030303030303 3.3030303030303 0.26244323091131 0.435509510119078 GO:0140311 protein sequestering activity 1/171 33/18639 0.0303030303030303 3.3030303030303 0.26244323091131 0.435509510119078 GO:0008236 serine-type peptidase activity 3/171 194/18639 0.0154639175257732 1.68556701030928 0.263381200819194 0.43571704826879 GO:0015035 protein-disulfide reductase activity 1/171 34/18639 0.0294117647058824 3.20588235294118 0.269221808118349 0.441293238995214 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/171 34/18639 0.0294117647058824 3.20588235294118 0.269221808118349 0.441293238995214 GO:0090482 vitamin transmembrane transporter activity 1/171 34/18639 0.0294117647058824 3.20588235294118 0.269221808118349 0.441293238995214 GO:1902936 phosphatidylinositol bisphosphate binding 2/171 111/18639 0.018018018018018 1.96396396396396 0.271028521102919 0.442900266192574 GO:0017171 serine hydrolase activity 3/171 198/18639 0.0151515151515152 1.65151515151515 0.273294917891863 0.445246431580664 GO:0005154 epidermal growth factor receptor binding 1/171 35/18639 0.0285714285714286 3.11428571428571 0.275938447237497 0.446836881327186 GO:0034061 DNA polymerase activity 1/171 35/18639 0.0285714285714286 3.11428571428571 0.275938447237497 0.446836881327186 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/171 36/18639 0.0277777777777778 3.02777777777778 0.282593710918555 0.453503679797441 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/171 36/18639 0.0277777777777778 3.02777777777778 0.282593710918555 0.453503679797441 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/171 36/18639 0.0277777777777778 3.02777777777778 0.282593710918555 0.453503679797441 GO:0035401 histone H3Y41 kinase activity 2/171 115/18639 0.0173913043478261 1.89565217391304 0.284623721398047 0.454042603182599 GO:0140801 histone H2AXY142 kinase activity 2/171 115/18639 0.0173913043478261 1.89565217391304 0.284623721398047 0.454042603182599 GO:0022829 wide pore channel activity 1/171 37/18639 0.027027027027027 2.94594594594595 0.28918815673014 0.454559683306027 GO:0023023 MHC protein complex binding 1/171 37/18639 0.027027027027027 2.94594594594595 0.28918815673014 0.454559683306027 GO:0030280 structural constituent of skin epidermis 1/171 37/18639 0.027027027027027 2.94594594594595 0.28918815673014 0.454559683306027 GO:0042805 actinin binding 1/171 37/18639 0.027027027027027 2.94594594594595 0.28918815673014 0.454559683306027 GO:0043394 proteoglycan binding 1/171 37/18639 0.027027027027027 2.94594594594595 0.28918815673014 0.454559683306027 GO:0140297 DNA-binding transcription factor binding 6/171 488/18639 0.0122950819672131 1.34016393442623 0.291517695259331 0.456811113424124 GO:0005109 frizzled binding 1/171 38/18639 0.0263157894736842 2.86842105263158 0.295722337205312 0.456811113424124 GO:0005501 retinoid binding 1/171 38/18639 0.0263157894736842 2.86842105263158 0.295722337205312 0.456811113424124 GO:0019840 isoprenoid binding 1/171 38/18639 0.0263157894736842 2.86842105263158 0.295722337205312 0.456811113424124 GO:0043531 ADP binding 1/171 38/18639 0.0263157894736842 2.86842105263158 0.295722337205312 0.456811113424124 GO:0005516 calmodulin binding 3/171 207/18639 0.0144927536231884 1.57971014492754 0.295734060369722 0.456811113424124 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/171 39/18639 0.0256410256410256 2.79487179487179 0.302196799886775 0.465452542354343 GO:0004540 RNA nuclease activity 2/171 121/18639 0.0165289256198347 1.80165289256198 0.304967676799271 0.468374426259052 GO:0050997 quaternary ammonium group binding 1/171 40/18639 0.025 2.725 0.308612087371687 0.472617368089212 GO:0017080 sodium channel regulator activity 1/171 41/18639 0.024390243902439 2.65853658536585 0.314968737356065 0.479611486428553 GO:0140318 protein transporter activity 1/171 41/18639 0.024390243902439 2.65853658536585 0.314968737356065 0.479611486428553 GO:0016859 cis-trans isomerase activity 1/171 42/18639 0.0238095238095238 2.5952380952381 0.321267282678794 0.486438597502354 GO:0042056 chemoattractant activity 1/171 42/18639 0.0238095238095238 2.5952380952381 0.321267282678794 0.486438597502354 GO:0008200 ion channel inhibitor activity 1/171 43/18639 0.0232558139534884 2.53488372093023 0.327508251365244 0.494491331638792 GO:0016248 channel inhibitor activity 1/171 44/18639 0.0227272727272727 2.47727272727273 0.333692166670501 0.50100560598148 GO:0043014 alpha-tubulin binding 1/171 44/18639 0.0227272727272727 2.47727272727273 0.333692166670501 0.50100560598148 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/171 45/18639 0.0222222222222222 2.42222222222222 0.3398195471222 0.505953547937497 GO:0008009 chemokine activity 1/171 45/18639 0.0222222222222222 2.42222222222222 0.3398195471222 0.505953547937497 GO:0141110 transporter inhibitor activity 1/171 45/18639 0.0222222222222222 2.42222222222222 0.3398195471222 0.505953547937497 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/171 48/18639 0.0208333333333333 2.27083333333333 0.357867594609634 0.518571343960225 GO:0032266 phosphatidylinositol-3-phosphate binding 1/171 48/18639 0.0208333333333333 2.27083333333333 0.357867594609634 0.518571343960225 GO:0140693 molecular condensate scaffold activity 1/171 48/18639 0.0208333333333333 2.27083333333333 0.357867594609634 0.518571343960225 GO:0005125 cytokine activity 3/171 234/18639 0.0128205128205128 1.3974358974359 0.363399763533317 0.518571343960225 GO:0005004 GPI-linked ephrin receptor activity 1/171 49/18639 0.0204081632653061 2.22448979591837 0.363773927852695 0.518571343960225 GO:0005008 hepatocyte growth factor receptor activity 1/171 49/18639 0.0204081632653061 2.22448979591837 0.363773927852695 0.518571343960225 GO:0005009 insulin receptor activity 1/171 49/18639 0.0204081632653061 2.22448979591837 0.363773927852695 0.518571343960225 GO:0005011 macrophage colony-stimulating factor receptor activity 1/171 49/18639 0.0204081632653061 2.22448979591837 0.363773927852695 0.518571343960225 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/171 49/18639 0.0204081632653061 2.22448979591837 0.363773927852695 0.518571343960225 GO:0005020 stem cell factor receptor activity 1/171 49/18639 0.0204081632653061 2.22448979591837 0.363773927852695 0.518571343960225 GO:0008288 boss receptor activity 1/171 49/18639 0.0204081632653061 2.22448979591837 0.363773927852695 0.518571343960225 GO:0016763 pentosyltransferase activity 1/171 49/18639 0.0204081632653061 2.22448979591837 0.363773927852695 0.518571343960225 GO:0035254 glutamate receptor binding 1/171 49/18639 0.0204081632653061 2.22448979591837 0.363773927852695 0.518571343960225 GO:0036332 placental growth factor receptor activity 1/171 49/18639 0.0204081632653061 2.22448979591837 0.363773927852695 0.518571343960225 GO:0038062 protein tyrosine kinase collagen receptor activity 1/171 49/18639 0.0204081632653061 2.22448979591837 0.363773927852695 0.518571343960225 GO:0060175 brain-derived neurotrophic factor receptor activity 1/171 49/18639 0.0204081632653061 2.22448979591837 0.363773927852695 0.518571343960225 GO:0004713 protein tyrosine kinase activity 2/171 140/18639 0.0142857142857143 1.55714285714286 0.368476536081564 0.519999133072656 GO:0005006 epidermal growth factor receptor activity 1/171 50/18639 0.02 2.18 0.369626249441571 0.519999133072656 GO:0005007 fibroblast growth factor receptor activity 1/171 50/18639 0.02 2.18 0.369626249441571 0.519999133072656 GO:0005017 platelet-derived growth factor receptor activity 1/171 50/18639 0.02 2.18 0.369626249441571 0.519999133072656 GO:0005019 platelet-derived growth factor beta-receptor activity 1/171 50/18639 0.02 2.18 0.369626249441571 0.519999133072656 GO:0003743 translation initiation factor activity 1/171 51/18639 0.0196078431372549 2.13725490196078 0.375425050417712 0.521315614051538 GO:0005010 insulin-like growth factor receptor activity 1/171 51/18639 0.0196078431372549 2.13725490196078 0.375425050417712 0.521315614051538 GO:0005021 vascular endothelial growth factor receptor activity 1/171 51/18639 0.0196078431372549 2.13725490196078 0.375425050417712 0.521315614051538 GO:0005030 neurotrophin receptor activity 1/171 51/18639 0.0196078431372549 2.13725490196078 0.375425050417712 0.521315614051538 GO:0030544 Hsp70 protein binding 1/171 51/18639 0.0196078431372549 2.13725490196078 0.375425050417712 0.521315614051538 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/171 52/18639 0.0192307692307692 2.09615384615385 0.381170817384495 0.526292186409247 GO:0019955 cytokine binding 2/171 144/18639 0.0138888888888889 1.51388888888889 0.381583109320307 0.526292186409247 GO:0005003 ephrin receptor activity 1/171 53/18639 0.0188679245283019 2.05660377358491 0.386864032547096 0.526292186409247 GO:0005005 transmembrane-ephrin receptor activity 1/171 53/18639 0.0188679245283019 2.05660377358491 0.386864032547096 0.526292186409247 GO:0008146 sulfotransferase activity 1/171 53/18639 0.0188679245283019 2.05660377358491 0.386864032547096 0.526292186409247 GO:0016860 intramolecular oxidoreductase activity 1/171 53/18639 0.0188679245283019 2.05660377358491 0.386864032547096 0.526292186409247 GO:0034212 protein N-acetyltransferase activity 1/171 53/18639 0.0188679245283019 2.05660377358491 0.386864032547096 0.526292186409247 GO:0038064 collagen receptor activity 1/171 53/18639 0.0188679245283019 2.05660377358491 0.386864032547096 0.526292186409247 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/171 54/18639 0.0185185185185185 2.01851851851852 0.392505173752005 0.532614615521708 GO:0008374 O-acyltransferase activity 1/171 55/18639 0.0181818181818182 1.98181818181818 0.398094714526199 0.538835270166775 GO:0019842 vitamin binding 2/171 150/18639 0.0133333333333333 1.45333333333333 0.401023901577836 0.54143277391869 GO:0170055 lipid transmembrane transporter activity 1/171 56/18639 0.0178571428571429 1.94642857142857 0.403633124115955 0.543586317904905 GO:0003774 cytoskeletal motor activity 2/171 153/18639 0.0130718954248366 1.42483660130719 0.410637789913848 0.551633722791535 GO:0003713 transcription coactivator activity 3/171 256/18639 0.01171875 1.27734375 0.417855016610934 0.558844812847541 GO:0070063 RNA polymerase binding 1/171 59/18639 0.0169491525423729 1.84745762711864 0.4199461948363 0.558844812847541 GO:0070888 E-box binding 1/171 59/18639 0.0169491525423729 1.84745762711864 0.4199461948363 0.558844812847541 GO:0140375 immune receptor activity 2/171 156/18639 0.0128205128205128 1.3974358974359 0.420176230555147 0.558844812847541 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/171 60/18639 0.0166666666666667 1.81666666666667 0.425284687876289 0.562845907905409 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/171 60/18639 0.0166666666666667 1.81666666666667 0.425284687876289 0.562845907905409 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/171 61/18639 0.0163934426229508 1.78688524590164 0.43057433308718 0.568442961908199 GO:0003730 mRNA 3'-UTR binding 3/171 262/18639 0.0114503816793893 1.24809160305344 0.432466397582505 0.569538056767133 GO:0008083 growth factor activity 2/171 162/18639 0.0123456790123457 1.34567901234568 0.43901482047432 0.576744960230969 GO:0004536 DNA nuclease activity 1/171 64/18639 0.015625 1.703125 0.446154605268876 0.584691609838918 GO:0019787 ubiquitin-like protein transferase activity 5/171 479/18639 0.0104384133611691 1.13778705636743 0.449071829270461 0.587079269485286 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/171 167/18639 0.0119760479041916 1.30538922155689 0.454458189355813 0.591236867705621 GO:0016874 ligase activity 2/171 167/18639 0.0119760479041916 1.30538922155689 0.454458189355813 0.591236867705621 GO:0016791 phosphatase activity 3/171 273/18639 0.010989010989011 1.1978021978022 0.458899310769766 0.595569081289576 GO:0016500 protein-hormone receptor activity 1/171 67/18639 0.0149253731343284 1.62686567164179 0.461311004707385 0.597252894983474 GO:0005126 cytokine receptor binding 3/171 275/18639 0.0109090909090909 1.18909090909091 0.463650806108651 0.59883573993792 GO:0030145 manganese ion binding 1/171 68/18639 0.0147058823529412 1.60294117647059 0.466270934612352 0.599331465113239 GO:1990841 promoter-specific chromatin binding 1/171 68/18639 0.0147058823529412 1.60294117647059 0.466270934612352 0.599331465113239 GO:0008080 N-acetyltransferase activity 1/171 69/18639 0.0144927536231884 1.57971014492754 0.471185461034262 0.604199538551111 GO:0005244 voltage-gated monoatomic ion channel activity 2/171 173/18639 0.0115606936416185 1.26011560693642 0.472667417695386 0.604653307600781 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/171 70/18639 0.0142857142857143 1.55714285714286 0.476054997176596 0.604657531958899 GO:0016782 transferase activity, transferring sulphur-containing groups 1/171 70/18639 0.0142857142857143 1.55714285714286 0.476054997176596 0.604657531958899 GO:0097110 scaffold protein binding 1/171 70/18639 0.0142857142857143 1.55714285714286 0.476054997176596 0.604657531958899 GO:0022832 voltage-gated channel activity 2/171 175/18639 0.0114285714285714 1.24571428571429 0.478656268106919 0.605916847721665 GO:0016755 aminoacyltransferase activity 5/171 496/18639 0.0100806451612903 1.09879032258065 0.479307357152959 0.605916847721665 GO:0035091 phosphatidylinositol binding 3/171 284/18639 0.0105633802816901 1.15140845070423 0.484804319721984 0.611066086312384 GO:0042379 chemokine receptor binding 1/171 72/18639 0.0138888888888889 1.51388888888889 0.485660732778126 0.611066086312384 GO:0016853 isomerase activity 2/171 180/18639 0.0111111111111111 1.21111111111111 0.49344641347196 0.619408144311406 GO:0003725 double-stranded RNA binding 1/171 75/18639 0.0133333333333333 1.45333333333333 0.499742026003563 0.625845154060537 GO:0051536 iron-sulfur cluster binding 1/171 76/18639 0.0131578947368421 1.43421052631579 0.504350090728482 0.63014370310132 GO:0051540 metal cluster binding 1/171 77/18639 0.012987012987013 1.41558441558442 0.508915954785231 0.634369655267171 GO:0004175 endopeptidase activity 4/171 405/18639 0.00987654320987654 1.07654320987654 0.511406589771998 0.635902498828874 GO:0019199 transmembrane receptor protein kinase activity 1/171 78/18639 0.0128205128205128 1.3974358974359 0.513440002394956 0.635902498828874 GO:0008234 cysteine-type peptidase activity 2/171 187/18639 0.0106951871657754 1.16577540106952 0.513704817150937 0.635902498828874 GO:0046332 SMAD binding 1/171 79/18639 0.0126582278481013 1.37974683544304 0.517922614301128 0.639646362362684 GO:0030971 receptor tyrosine kinase binding 1/171 81/18639 0.0123456790123457 1.34567901234568 0.52676503677578 0.649071401636364 GO:0001540 amyloid-beta binding 1/171 83/18639 0.0120481927710843 1.31325301204819 0.535446199785521 0.65674865694517 GO:0030165 PDZ domain binding 1/171 83/18639 0.0120481927710843 1.31325301204819 0.535446199785521 0.65674865694517 GO:0004860 protein kinase inhibitor activity 1/171 84/18639 0.0119047619047619 1.29761904761905 0.539727224782108 0.66048811069226 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/171 86/18639 0.0116279069767442 1.26744186046512 0.548171964412493 0.66929424356514 GO:0008168 methyltransferase activity 2/171 204/18639 0.00980392156862745 1.06862745098039 0.560644733484204 0.682967220789848 GO:0019210 kinase inhibitor activity 1/171 90/18639 0.0111111111111111 1.21111111111111 0.564602092896497 0.686228394087353 GO:0004518 nuclease activity 2/171 209/18639 0.00956937799043062 1.04306220095694 0.573826014279037 0.695861410980914 GO:0004867 serine-type endopeptidase inhibitor activity 1/171 95/18639 0.0105263157894737 1.14736842105263 0.584306830800885 0.70697169595773 GO:0016407 acetyltransferase activity 1/171 96/18639 0.0104166666666667 1.13541666666667 0.58814006699227 0.709764632295582 GO:0016741 transferase activity, transferring one-carbon groups 2/171 215/18639 0.00930232558139535 1.01395348837209 0.589263547334952 0.709764632295582 GO:0004842 ubiquitin-protein transferase activity 4/171 449/18639 0.0089086859688196 0.971046770601336 0.593031146433357 0.712701108718115 GO:0008170 N-methyltransferase activity 1/171 98/18639 0.0102040816326531 1.11224489795918 0.595701431731752 0.712714212964775 GO:0042626 ATPase-coupled transmembrane transporter activity 1/171 98/18639 0.0102040816326531 1.11224489795918 0.595701431731752 0.712714212964775 GO:0022804 active transmembrane transporter activity 4/171 457/18639 0.0087527352297593 0.954048140043764 0.606996894872993 0.724610992543261 GO:0005253 monoatomic anion channel activity 1/171 103/18639 0.00970873786407767 1.05825242718447 0.614006461556515 0.731349918653982 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 3/171 349/18639 0.00859598853868195 0.936962750716333 0.623996098625085 0.740666012112255 GO:0008013 beta-catenin binding 1/171 106/18639 0.00943396226415094 1.02830188679245 0.624591487826006 0.740666012112255 GO:0005085 guanyl-nucleotide exchange factor activity 2/171 230/18639 0.00869565217391304 0.947826086956522 0.626037549526871 0.740742001206187 GO:0004843 cysteine-type deubiquitinase activity 1/171 108/18639 0.00925925925925926 1.00925925925926 0.631487340148563 0.745544524933106 GO:0004222 metalloendopeptidase activity 1/171 110/18639 0.00909090909090909 0.990909090909091 0.638257250261549 0.751881068439978 GO:0042578 phosphoric ester hydrolase activity 3/171 363/18639 0.00826446280991736 0.900826446280992 0.650422621045612 0.764466712145665 GO:0005539 glycosaminoglycan binding 2/171 242/18639 0.00826446280991736 0.900826446280992 0.653593098342852 0.764466712145665 GO:0001221 transcription coregulator binding 1/171 115/18639 0.00869565217391304 0.947826086956522 0.654645934468023 0.764466712145665 GO:0101005 deubiquitinase activity 1/171 115/18639 0.00869565217391304 0.947826086956522 0.654645934468023 0.764466712145665 GO:0030695 GTPase regulator activity 4/171 489/18639 0.0081799591002045 0.891615541922291 0.659880968483876 0.765744344842297 GO:1990782 protein tyrosine kinase binding 1/171 117/18639 0.00854700854700855 0.931623931623932 0.660992786749962 0.765744344842297 GO:0046982 protein heterodimerization activity 3/171 369/18639 0.00813008130081301 0.886178861788618 0.66133957108731 0.765744344842297 GO:0060589 nucleoside-triphosphatase regulator activity 4/171 490/18639 0.00816326530612245 0.889795918367347 0.661454536682806 0.765744344842297 GO:0042393 histone binding 2/171 247/18639 0.00809716599190283 0.882591093117409 0.664591253513493 0.767717482506967 GO:0003697 single-stranded DNA binding 1/171 121/18639 0.00826446280991736 0.900826446280992 0.673340683263225 0.776151841352878 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/171 122/18639 0.00819672131147541 0.89344262295082 0.676357139854756 0.777955851850106 GO:0019783 ubiquitin-like protein peptidase activity 1/171 127/18639 0.0078740157480315 0.858267716535433 0.691029043674622 0.793009241266591 GO:0001653 peptide receptor activity 1/171 128/18639 0.0078125 0.8515625 0.693883086108267 0.793009241266591 GO:0031490 chromatin DNA binding 1/171 128/18639 0.0078125 0.8515625 0.693883086108267 0.793009241266591 GO:0035591 signaling adaptor activity 1/171 129/18639 0.00775193798449612 0.844961240310078 0.696710917790807 0.794546919012495 GO:0005262 calcium channel activity 1/171 131/18639 0.00763358778625954 0.83206106870229 0.702288903968024 0.7992077548341 GO:0005179 hormone activity 1/171 132/18639 0.00757575757575758 0.825757575757576 0.705039530584702 0.800638111002966 GO:0005096 GTPase activator activity 2/171 271/18639 0.00738007380073801 0.804428044280443 0.713526259396657 0.808562526504457 GO:0016779 nucleotidyltransferase activity 1/171 136/18639 0.00735294117647059 0.801470588235294 0.715791669293229 0.809418427723988 GO:1901681 sulfur compound binding 2/171 275/18639 0.00727272727272727 0.792727272727273 0.721078137269935 0.813101023269741 GO:0070851 growth factor receptor binding 1/171 139/18639 0.00719424460431655 0.784172661870504 0.723599231529228 0.813101023269741 GO:0140767 enzyme-substrate adaptor activity 1/171 139/18639 0.00719424460431655 0.784172661870504 0.723599231529228 0.813101023269741 GO:0001217 DNA-binding transcription repressor activity 2/171 278/18639 0.00719424460431655 0.784172661870504 0.726632109007906 0.814800858636481 GO:0015293 symporter activity 1/171 146/18639 0.00684931506849315 0.746575342465753 0.740997506309531 0.829174662592711 GO:0015085 calcium ion transmembrane transporter activity 1/171 147/18639 0.00680272108843537 0.741496598639456 0.743392435548761 0.83012155302945 GO:0008509 monoatomic anion transmembrane transporter activity 1/171 149/18639 0.00671140939597315 0.731543624161074 0.748116444317 0.833659904685888 GO:0004866 endopeptidase inhibitor activity 1/171 161/18639 0.0062111801242236 0.677018633540373 0.774698773125356 0.861490751857242 GO:0030414 peptidase inhibitor activity 1/171 169/18639 0.00591715976331361 0.644970414201183 0.790851305495006 0.877262746477189 GO:0022836 gated channel activity 2/171 318/18639 0.00628930817610063 0.685534591194969 0.792155166595073 0.877262746477189 GO:0008201 heparin binding 1/171 172/18639 0.00581395348837209 0.633720930232558 0.796607055339099 0.880373982807746 GO:0140097 catalytic activity, acting on DNA 2/171 336/18639 0.00595238095238095 0.648809523809524 0.816862605710825 0.898565953767535 GO:0008237 metallopeptidase activity 1/171 184/18639 0.00543478260869565 0.592391304347826 0.81809736089283 0.898565953767535 GO:0061135 endopeptidase regulator activity 1/171 184/18639 0.00543478260869565 0.592391304347826 0.81809736089283 0.898565953767535 GO:0046943 carboxylic acid transmembrane transporter activity 1/171 188/18639 0.00531914893617021 0.579787234042553 0.824746648660644 0.902107496843225 GO:0140597 protein carrier chaperone 1/171 188/18639 0.00531914893617021 0.579787234042553 0.824746648660644 0.902107496843225 GO:0005342 organic acid transmembrane transporter activity 1/171 189/18639 0.00529100529100529 0.576719576719577 0.826370859981387 0.902107496843225 GO:0061630 ubiquitin protein ligase activity 2/171 353/18639 0.0056657223796034 0.617563739376771 0.837764044686583 0.912096025295778 GO:0141003 histone H2AX kinase activity 2/171 354/18639 0.00564971751412429 0.615819209039548 0.838924142669437 0.912096025295778 GO:0140996 histone H3 kinase activity 2/171 357/18639 0.00560224089635854 0.610644257703081 0.842359792422862 0.913977426596466 GO:0035173 histone kinase activity 2/171 360/18639 0.00555555555555556 0.605555555555556 0.84572927853565 0.915779582414361 GO:0061659 ubiquitin-like protein ligase activity 2/171 372/18639 0.00537634408602151 0.586021505376344 0.858566026214282 0.924939666555956 GO:0140098 catalytic activity, acting on RNA 2/171 387/18639 0.00516795865633075 0.563307493540052 0.873244430663941 0.924939666555956 GO:0061134 peptidase regulator activity 1/171 226/18639 0.00442477876106195 0.482300884955752 0.877015588171179 0.924939666555956 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/171 243/18639 0.00411522633744856 0.448559670781893 0.89506164520762 0.924939666555956 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0004711 ribosomal protein S6 kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0035175 histone H3S10 kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0035979 histone H2AXS139 kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0044022 histone H3S28 kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0044023 histone H4S1 kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0044024 histone H2AS1 kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0044025 histone H2BS14 kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0072354 histone H3T3 kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0072371 histone H2AS121 kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0140823 histone H2BS36 kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0140855 histone H3S57 kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0140995 histone H2A kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0140997 histone H4 kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0140998 histone H2B kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:1990244 histone H2AT120 kinase activity 1/171 245/18639 0.00408163265306122 0.444897959183673 0.897003539156335 0.924939666555956 GO:0004677 DNA-dependent protein kinase activity 1/171 246/18639 0.0040650406504065 0.443089430894309 0.897961046756871 0.924939666555956 GO:0140857 histone H3T45 kinase activity 1/171 246/18639 0.0040650406504065 0.443089430894309 0.897961046756871 0.924939666555956 GO:0035402 histone H3T11 kinase activity 1/171 247/18639 0.00404858299595142 0.441295546558705 0.898909704452983 0.924939666555956 GO:0035403 histone H3T6 kinase activity 1/171 247/18639 0.00404858299595142 0.441295546558705 0.898909704452983 0.924939666555956 GO:0004679 AMP-activated protein kinase activity 1/171 248/18639 0.00403225806451613 0.439516129032258 0.899849593564473 0.924939666555956 GO:0042277 peptide binding 1/171 249/18639 0.00401606425702811 0.437751004016064 0.9007807946683 0.924939666555956 GO:0016757 glycosyltransferase activity 1/171 267/18639 0.00374531835205993 0.408239700374532 0.916144350200798 0.936926085140481 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 1/171 268/18639 0.00373134328358209 0.406716417910448 0.916924848574174 0.936926085140481 GO:0008514 organic anion transmembrane transporter activity 1/171 269/18639 0.00371747211895911 0.405204460966543 0.917698124437971 0.936926085140481 GO:0005216 monoatomic ion channel activity 2/171 448/18639 0.00446428571428571 0.486607142857143 0.919636100529159 0.937119676584846 GO:0030246 carbohydrate binding 1/171 280/18639 0.00357142857142857 0.389285714285714 0.925746049245186 0.941555754071005 GO:0031267 small GTPase binding 1/171 283/18639 0.00353356890459364 0.385159010600707 0.927801750238521 0.941859352514862 GO:0015291 secondary active transmembrane transporter activity 1/171 287/18639 0.00348432055749129 0.379790940766551 0.930454928188722 0.942767186217685 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 2/171 484/18639 0.00413223140495868 0.450413223140496 0.938998756946472 0.949628931553413 GO:0001216 DNA-binding transcription activator activity 2/171 491/18639 0.00407331975560081 0.443991853360489 0.942212636244346 0.951084694966045 GO:0051020 GTPase binding 1/171 315/18639 0.00317460317460317 0.346031746031746 0.946501156154064 0.953617706200335 GO:0005261 monoatomic cation channel activity 1/171 341/18639 0.00293255131964809 0.319648093841642 0.958081763116152 0.963474343396356 GO:0106310 protein serine kinase activity 1/171 361/18639 0.00277008310249307 0.301939058171745 0.965261851585876 0.968877064513164 GO:0004674 protein serine/threonine kinase activity 1/171 433/18639 0.0023094688221709 0.251732101616628 0.98236744386434 0.984203644693993 GO:0046873 metal ion transmembrane transporter activity 1/171 450/18639 0.00222222222222222 0.242222222222222 0.984982009104291 0.984982009104291