ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	199/4284	495/18639	0.402020202020202	1.74912571089042	3.37085047246973e-18	4.46300602554993e-15
GO:0019787	ubiquitin-like protein transferase activity	190/4284	479/18639	0.396659707724426	1.72580305608674	1.01640631862311e-16	6.72860982928498e-14
GO:0016755	aminoacyltransferase activity	192/4284	496/18639	0.387096774193548	1.68419625914882	1.29059133942409e-15	5.69580977799165e-13
GO:0004842	ubiquitin-protein transferase activity	174/4284	449/18639	0.387527839643653	1.68607175609665	2.53204583388807e-14	8.3810717101695e-12
GO:0044389	ubiquitin-like protein ligase binding	124/4284	322/18639	0.385093167701863	1.67547888720706	2.14068178840655e-10	5.66852537570055e-08
GO:0061659	ubiquitin-like protein ligase activity	137/4284	372/18639	0.368279569892473	1.60232560766242	8.4754039719591e-10	1.87023914314564e-07
GO:0051082	unfolded protein binding	58/4284	121/18639	0.479338842975207	2.08552677269255	1.44894087445857e-09	2.74056816826164e-07
GO:0031625	ubiquitin protein ligase binding	115/4284	302/18639	0.380794701986755	1.65677694919027	2.07389764257428e-09	2.909432811555e-07
GO:0140297	DNA-binding transcription factor binding	169/4284	488/18639	0.346311475409836	1.50674593607935	2.16885028202214e-09	2.909432811555e-07
GO:0003713	transcription coactivator activity	101/4284	256/18639	0.39453125	1.71654247636555	2.19745680631043e-09	2.909432811555e-07
GO:0061630	ubiquitin protein ligase activity	127/4284	353/18639	0.359773371104816	1.5653164948699	1.75198347783293e-08	2.10875102240982e-06
GO:0042393	histone binding	93/4284	247/18639	0.376518218623482	1.63817065287654	1.29198498422168e-07	1.42549009925793e-05
GO:0031072	heat shock protein binding	57/4284	131/18639	0.435114503816794	1.89311373404324	1.46178625811801e-07	1.4887730813448e-05
GO:0051087	protein-folding chaperone binding	57/4284	134/18639	0.425373134328358	1.85073059074376	3.68626753693203e-07	3.34123101037477e-05
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	121/4284	349/18639	0.346704871060172	1.50845753774289	3.78538256462399e-07	3.34123101037477e-05
GO:0140662	ATP-dependent protein folding chaperone	24/4284	40/18639	0.6	2.61050420168067	5.41693534101233e-07	4.25535770876212e-05
GO:0043021	ribonucleoprotein complex binding	70/4284	177/18639	0.395480225988701	1.72067131937521	5.46382787378823e-07	4.25535770876212e-05
GO:0061650	ubiquitin-like protein conjugating enzyme activity	24/4284	41/18639	0.585365853658537	2.54683336749334	1.02161432526333e-06	7.51454092582586e-05
GO:0060590	ATPase regulator activity	27/4284	49/18639	0.551020408163265	2.39740181787	1.13998976853565e-06	7.9439287028484e-05
GO:0003697	single-stranded DNA binding	51/4284	121/18639	0.421487603305785	1.83382526564345	2.06238332909606e-06	0.000136529776386159
GO:0004532	RNA exonuclease activity	23/4284	40/18639	0.575	2.50173319327731	2.63651794030257e-06	0.00016622617871241
GO:0010485	histone H4 acetyltransferase activity	21/4284	35/18639	0.6	2.61050420168067	2.79239323901243e-06	0.000168051302202384
GO:0140098	catalytic activity, acting on RNA	128/4284	387/18639	0.330749354005168	1.4390376305561	3.02402551504182e-06	0.000174078686170233
GO:0140852	histone ubiquitin ligase activity	11/4284	13/18639	0.846153846153846	3.68148028442146	4.55677964702577e-06	0.000251382343860922
GO:0140030	modification-dependent protein binding	66/4284	173/18639	0.38150289017341	1.65985816291835	4.88234493065096e-06	0.000258568987527275
GO:0060589	nucleoside-triphosphatase regulator activity	155/4284	490/18639	0.316326530612245	1.37628622877723	5.33995713112772e-06	0.000263042835128387
GO:0019207	kinase regulator activity	99/4284	287/18639	0.344947735191638	1.50081252013	5.36416657739158e-06	0.000263042835128387
GO:0045296	cadherin binding	112/4284	334/18639	0.335329341317365	1.45896442409299	6.05779401256034e-06	0.000286447116879639
GO:0030695	GTPase regulator activity	154/4284	489/18639	0.314928425357873	1.37020329604234	7.50251225111161e-06	0.000342528490361095
GO:0106310	protein serine kinase activity	119/4284	361/18639	0.329639889196676	1.43421052631579	7.92378198791969e-06	0.000344640940529692
GO:0004402	histone acetyltransferase activity	23/4284	42/18639	0.547619047619048	2.38260304121649	8.13261409012395e-06	0.000344640940529692
GO:0034212	protein N-acetyltransferase activity	27/4284	53/18639	0.509433962264151	2.21646583161567	8.32969040555147e-06	0.000344640940529692
GO:0019887	protein kinase regulator activity	89/4284	255/18639	0.349019607843137	1.51852858790575	9.27656169127882e-06	0.000372186899371308
GO:0070063	RNA polymerase binding	29/4284	59/18639	0.491525423728814	2.1385486397949	9.65160123921679e-06	0.000375844707080089
GO:0001671	ATPase activator activity	17/4284	27/18639	0.62962962962963	2.73941798941799	1.01240141384153e-05	0.00038297699197891
GO:0003714	transcription corepressor activity	74/4284	204/18639	0.362745098039216	1.57824600428407	1.12494823203944e-05	0.000413730960894505
GO:0061631	ubiquitin conjugating enzyme activity	20/4284	35/18639	0.571428571428571	2.48619447779112	1.35139568031108e-05	0.000447719905299017
GO:0016407	acetyltransferase activity	41/4284	96/18639	0.427083333333333	1.85817139355742	1.36101202112818e-05	0.000447719905299017
GO:0140097	catalytic activity, acting on DNA	111/4284	336/18639	0.330357142857143	1.43733118247299	1.413080169542e-05	0.000447719905299017
GO:0043995	histone H4K5 acetyltransferase activity	18/4284	30/18639	0.6	2.61050420168067	1.45158960045591e-05	0.000447719905299017
GO:0043996	histone H4K8 acetyltransferase activity	18/4284	30/18639	0.6	2.61050420168067	1.45158960045591e-05	0.000447719905299017
GO:0043997	histone H4K12 acetyltransferase activity	18/4284	30/18639	0.6	2.61050420168067	1.45158960045591e-05	0.000447719905299017
GO:0019210	kinase inhibitor activity	39/4284	90/18639	0.433333333333333	1.88536414565826	1.45407522113729e-05	0.000447719905299017
GO:0004860	protein kinase inhibitor activity	37/4284	84/18639	0.44047619047619	1.91644157663065	1.52929960755817e-05	0.000460180154637957
GO:0008080	N-acetyltransferase activity	32/4284	69/18639	0.463768115942029	2.01778102545366	1.57788732151392e-05	0.000464249514152094
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	21/4284	38/18639	0.552631578947368	2.40441176470588	1.66621854085614e-05	0.000479581162629029
GO:0008094	ATP-dependent activity, acting on DNA	75/4284	210/18639	0.357142857142857	1.55387154861945	1.84301335695413e-05	0.000519180783958993
GO:0061733	protein-lysine-acetyltransferase activity	24/4284	47/18639	0.51063829787234	2.22170570355802	2.49364915004379e-05	0.000687831557220412
GO:0016922	nuclear receptor binding	53/4284	137/18639	0.386861313868613	1.68317180886953	2.56349649743816e-05	0.000692667216858802
GO:0000287	magnesium ion binding	80/4284	230/18639	0.347826086956522	1.51333576909024	2.93797939886881e-05	0.000777976944820461
GO:0016791	phosphatase activity	92/4284	273/18639	0.336996336996337	1.46621725613322	3.17616992395641e-05	0.000824558623395742
GO:0010484	histone H3 acetyltransferase activity	17/4284	29/18639	0.586206896551724	2.55049261083744	3.84442675613177e-05	0.000956247921437949
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	24/4284	48/18639	0.5	2.17542016806723	3.90477413869589e-05	0.000956247921437949
GO:0140857	histone H3T45 kinase activity	84/4284	246/18639	0.341463414634146	1.48565279770445	4.04097560288916e-05	0.000956247921437949
GO:0003725	double-stranded RNA binding	33/4284	75/18639	0.44	1.91436974789916	4.4512188177862e-05	0.000956247921437949
GO:0051020	GTPase binding	103/4284	315/18639	0.326984126984127	1.42265572895825	4.51419949371468e-05	0.000956247921437949
GO:0004674	protein serine/threonine kinase activity	135/4284	433/18639	0.311778290993072	1.35649756438372	4.54255998459415e-05	0.000956247921437949
GO:0002039	p53 binding	31/4284	69/18639	0.449275362318841	1.95472536840823	4.59957867238728e-05	0.000956247921437949
GO:0061775	cohesin loader activity	57/4284	153/18639	0.372549019607843	1.62090130169715	4.628763489685e-05	0.000956247921437949
GO:0035403	histone H3T6 kinase activity	84/4284	247/18639	0.340080971659919	1.47963800904977	4.76051693088494e-05	0.000956247921437949
GO:0003689	DNA clamp loader activity	59/4284	160/18639	0.36875	1.60437237394958	4.85112560466135e-05	0.000956247921437949
GO:0031267	small GTPase binding	94/4284	283/18639	0.332155477031802	1.44515544733795	4.90960414406942e-05	0.000956247921437949
GO:0140517	protein-RNA adaptor activity	14/4284	22/18639	0.636363636363636	2.76871657754011	5.31230088027812e-05	0.000956247921437949
GO:0004679	AMP-activated protein kinase activity	84/4284	248/18639	0.338709677419355	1.47367172675522	5.59674259638788e-05	0.000956247921437949
GO:0000175	3'-5'-RNA exonuclease activity	19/4284	35/18639	0.542857142857143	2.36188475390156	5.85746899535127e-05	0.000956247921437949
GO:0004676	3-phosphoinositide-dependent protein kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0004711	ribosomal protein S6 kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0035175	histone H3S10 kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0035979	histone H2AXS139 kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0044022	histone H3S28 kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0044023	histone H4S1 kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0044024	histone H2AS1 kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0044025	histone H2BS14 kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0072354	histone H3T3 kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0072371	histone H2AS121 kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0072518	Rho-dependent protein serine/threonine kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0140823	histone H2BS36 kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0140855	histone H3S57 kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0140995	histone H2A kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0140997	histone H4 kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0140998	histone H2B kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:1990244	histone H2AT120 kinase activity	83/4284	245/18639	0.338775510204082	1.47395815469045	6.12838738276902e-05	0.000956247921437949
GO:0000510	H3-H4 histone complex chaperone activity	56/4284	151/18639	0.370860927152318	1.61355668095053	6.21127803955163e-05	0.000956247921437949
GO:0140584	chromatin extrusion motor activity	56/4284	151/18639	0.370860927152318	1.61355668095053	6.21127803955163e-05	0.000956247921437949
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	56/4284	151/18639	0.370860927152318	1.61355668095053	6.21127803955163e-05	0.000956247921437949
GO:0140849	ATP-dependent H2AZ histone chaperone activity	56/4284	151/18639	0.370860927152318	1.61355668095053	6.21127803955163e-05	0.000956247921437949
GO:0004677	DNA-dependent protein kinase activity	83/4284	246/18639	0.33739837398374	1.46796645487463	7.19130258356668e-05	0.00109440053110831
GO:0001221	transcription coregulator binding	45/4284	115/18639	0.391304347826087	1.70250274022653	7.33806479629199e-05	0.00110404520344211
GO:0017025	TBP-class protein binding	15/4284	25/18639	0.6	2.61050420168067	7.63462976733445e-05	0.0011142618063931
GO:0015616	DNA translocase activity	56/4284	152/18639	0.368421052631579	1.60294117647059	7.6584459502849e-05	0.0011142618063931
GO:0140674	ATP-dependent histone chaperone activity	56/4284	152/18639	0.368421052631579	1.60294117647059	7.6584459502849e-05	0.0011142618063931
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	82/4284	243/18639	0.337448559670782	1.46818480478611	7.87564442799564e-05	0.00113340795898546
GO:0035402	histone H3T11 kinase activity	83/4284	247/18639	0.336032388663968	1.4620232708468	8.42151727364355e-05	0.00119893428712947
GO:0000993	RNA polymerase II complex binding	19/4284	36/18639	0.527777777777778	2.29627684407096	9.73911089406642e-05	0.00137176413018553
GO:0036408	histone H3K14 acetyltransferase activity	16/4284	28/18639	0.571428571428571	2.48619447779112	9.96068803445945e-05	0.00138820536396045
GO:0140104	molecular carrier activity	83/4284	249/18639	0.333333333333333	1.45028011204482	0.000114804068528788	0.0015833394451262
GO:0043175	RNA polymerase core enzyme binding	21/4284	42/18639	0.5	2.17542016806723	0.000117796522009528	0.00160038397692642
GO:0044183	protein folding chaperone	32/4284	75/18639	0.426666666666667	1.85635854341737	0.00011845742427401	0.00160038397692642
GO:0005096	GTPase activator activity	89/4284	271/18639	0.328413284132841	1.42887376352755	0.00012067124813998	0.00161382558118519
GO:0140658	ATP-dependent chromatin remodeler activity	57/4284	158/18639	0.360759493670886	1.56960695670673	0.000128791936171207	0.001700967002125
GO:0030544	Hsp70 protein binding	24/4284	51/18639	0.470588235294118	2.04745427582798	0.000133584823610973	0.001700967002125
GO:0035173	histone kinase activity	113/4284	360/18639	0.313888888888889	1.3656804388422	0.000134895177869808	0.001700967002125
GO:0001098	basal transcription machinery binding	27/4284	60/18639	0.45	1.9578781512605	0.000134895419352814	0.001700967002125
GO:0001099	basal RNA polymerase II transcription machinery binding	27/4284	60/18639	0.45	1.9578781512605	0.000134895419352814	0.001700967002125
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	27/4284	60/18639	0.45	1.9578781512605	0.000134895419352814	0.001700967002125
GO:0004386	helicase activity	56/4284	155/18639	0.361290322580645	1.5719165085389	0.000140406192477475	0.001752555234321
GO:0008170	N-methyltransferase activity	39/4284	98/18639	0.397959183673469	1.73145686846167	0.000141633995522921	0.001752555234321
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	48/4284	128/18639	0.375	1.63156512605042	0.000147437832641603	0.00180747861497668
GO:0015631	tubulin binding	119/4284	385/18639	0.309090909090909	1.34480519480519	0.00018451337694628	0.00224124505575115
GO:0140597	protein carrier chaperone	65/4284	188/18639	0.345744680851064	1.50427990345074	0.000190258387060268	0.00229001913152541
GO:0005525	GTP binding	117/4284	378/18639	0.30952380952381	1.34668867547019	0.000195461070307435	0.00233144555934273
GO:0051059	NF-kappaB binding	17/4284	32/18639	0.53125	2.31138392857143	0.00020372164919204	0.00240828092437733
GO:0140713	histone chaperone activity	58/4284	164/18639	0.353658536585366	1.53871182619389	0.000208763057077592	0.00244603794310382
GO:0016303	1-phosphatidylinositol-3-kinase activity	8/4284	10/18639	0.8	3.48067226890756	0.000221109490211943	0.00256797337754923
GO:0004721	phosphoprotein phosphatase activity	61/4284	175/18639	0.348571428571429	1.51657863145258	0.000229191299413996	0.00263868939499244
GO:0032182	ubiquitin-like protein binding	45/4284	120/18639	0.375	1.63156512605042	0.000233639853846214	0.00266671695252058
GO:0019783	ubiquitin-like protein peptidase activity	47/4284	127/18639	0.37007874015748	1.61015351022299	0.000245900254156524	0.0027826661239593
GO:0004527	exonuclease activity	34/4284	84/18639	0.404761904761905	1.76105442176871	0.000252391617745932	0.00283191950758995
GO:0043014	alpha-tubulin binding	21/4284	44/18639	0.477272727272727	2.07653743315508	0.000271197916435745	0.00301736169210862
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	13/4284	22/18639	0.590909090909091	2.57095110771581	0.000288020134453395	0.00317782215013579
GO:0019003	GDP binding	31/4284	75/18639	0.413333333333333	1.79834733893557	0.000299429866230802	0.00327640613958332
GO:0140416	transcription regulator inhibitor activity	17/4284	33/18639	0.515151515151515	2.24134199134199	0.000330589498217348	0.00358770898065384
GO:0008276	protein methyltransferase activity	37/4284	95/18639	0.389473684210526	1.69453781512605	0.000343895842021488	0.00368335385257681
GO:0016887	ATP hydrolysis activity	126/4284	417/18639	0.302158273381295	1.31464240372408	0.000344966675014747	0.00368335385257681
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	58/4284	167/18639	0.347305389221557	1.51107029638203	0.000358343319185034	0.00378398856290735
GO:0140996	histone H3 kinase activity	110/4284	357/18639	0.30812324929972	1.34059506155403	0.00036010767290508	0.00378398856290735
GO:0140789	histone phosphatase activity	49/4284	136/18639	0.360294117647059	1.5675821799308	0.000381579594812487	0.00397804239001364
GO:0140463	chromatin-protein adaptor activity	24/4284	54/18639	0.444444444444444	1.93370681605976	0.000392885429428629	0.00403242827382589
GO:0141003	histone H2AX kinase activity	109/4284	354/18639	0.307909604519774	1.33966552722784	0.000392887649035906	0.00403242827382589
GO:0003727	single-stranded RNA binding	35/4284	89/18639	0.393258426966292	1.71100462656973	0.000396544714355291	0.00403865539851081
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	75/4284	229/18639	0.327510917030568	1.42494770834098	0.000432752169385942	0.00437377001730525
GO:0004535	poly(A)-specific ribonuclease activity	9/4284	13/18639	0.692307692307692	3.01212023270847	0.000506138405792665	0.00507672158537491
GO:0044013	histone H2B acetyltransferase activity	13/4284	23/18639	0.565217391304348	2.45917062477165	0.000523331109044297	0.00520970216823044
GO:0008408	3'-5' exonuclease activity	25/4284	58/18639	0.431034482758621	1.87536221385106	0.000528984280841559	0.00522668050622556
GO:0015036	disulfide oxidoreductase activity	19/4284	40/18639	0.475	2.06664915966387	0.000566758440869491	0.00555843093119412
GO:0001222	transcription corepressor binding	22/4284	49/18639	0.448979591836735	1.95343851826445	0.000571414777465319	0.00556289092179472
GO:0016410	N-acyltransferase activity	36/4284	94/18639	0.382978723404255	1.66627927766851	0.00059660666966257	0.00576574620900177
GO:0070990	snRNP binding	8/4284	11/18639	0.727272727272727	3.16424751718869	0.000646402896083118	0.00615710384470538
GO:0140537	transcription regulator activator activity	8/4284	11/18639	0.727272727272727	3.16424751718869	0.000646402896083118	0.00615710384470538
GO:0004725	protein tyrosine phosphatase activity	37/4284	98/18639	0.377551020408163	1.64266420854056	0.000693052678210116	0.00655429818535853
GO:0070717	poly-purine tract binding	16/4284	32/18639	0.5	2.17542016806723	0.000756821477405236	0.00710660734811725
GO:0008168	methyltransferase activity	67/4284	204/18639	0.32843137254902	1.42895246333828	0.000778977263781157	0.00726314012145248
GO:0043998	histone H2A acetyltransferase activity	13/4284	24/18639	0.541666666666667	2.35670518207283	0.000902464046505956	0.00835568110191528
GO:0008234	cysteine-type peptidase activity	62/4284	187/18639	0.331550802139037	1.44252460342426	0.000915939770135038	0.00842155733096382
GO:0019001	guanyl nucleotide binding	119/4284	400/18639	0.2975	1.294375	0.000939478514226725	0.00851965447148071
GO:0032561	guanyl ribonucleotide binding	119/4284	400/18639	0.2975	1.294375	0.000939478514226725	0.00851965447148071
GO:0016278	lysine N-methyltransferase activity	28/4284	70/18639	0.4	1.74033613445378	0.00106545776290516	0.00959636787813897
GO:0043130	ubiquitin binding	37/4284	100/18639	0.37	1.60981092436975	0.0010729219951489	0.00959830217281858
GO:1990825	sequence-specific mRNA binding	9/4284	14/18639	0.642857142857143	2.79696878751501	0.00112770761724321	0.0100207039277182
GO:0140311	protein sequestering activity	16/4284	33/18639	0.484848484848485	2.10949834479246	0.00115798098722912	0.010221112180609
GO:0032931	histone H3K56 acetyltransferase activity	12/4284	22/18639	0.545454545454545	2.37318563789152	0.00131348465082953	0.0106690409674742
GO:0043992	histone H3K9 acetyltransferase activity	12/4284	22/18639	0.545454545454545	2.37318563789152	0.00131348465082953	0.0106690409674742
GO:0043993	histone H3K18 acetyltransferase activity	12/4284	22/18639	0.545454545454545	2.37318563789152	0.00131348465082953	0.0106690409674742
GO:0043994	histone H3K23 acetyltransferase activity	12/4284	22/18639	0.545454545454545	2.37318563789152	0.00131348465082953	0.0106690409674742
GO:0043999	histone H2AK5 acetyltransferase activity	12/4284	22/18639	0.545454545454545	2.37318563789152	0.00131348465082953	0.0106690409674742
GO:0044012	histone H2AK9 acetyltransferase activity	12/4284	22/18639	0.545454545454545	2.37318563789152	0.00131348465082953	0.0106690409674742
GO:0044014	histone H2BK5 acetyltransferase activity	12/4284	22/18639	0.545454545454545	2.37318563789152	0.00131348465082953	0.0106690409674742
GO:0044015	histone H2BK12 acetyltransferase activity	12/4284	22/18639	0.545454545454545	2.37318563789152	0.00131348465082953	0.0106690409674742
GO:0044016	histone H3K4 acetyltransferase activity	12/4284	22/18639	0.545454545454545	2.37318563789152	0.00131348465082953	0.0106690409674742
GO:0044017	histone H3K27 acetyltransferase activity	12/4284	22/18639	0.545454545454545	2.37318563789152	0.00131348465082953	0.0106690409674742
GO:0044018	histone H3K36 acetyltransferase activity	12/4284	22/18639	0.545454545454545	2.37318563789152	0.00131348465082953	0.0106690409674742
GO:0046972	histone H4K16 acetyltransferase activity	12/4284	22/18639	0.545454545454545	2.37318563789152	0.00131348465082953	0.0106690409674742
GO:0140908	histone H3K122 acetyltransferase activity	12/4284	22/18639	0.545454545454545	2.37318563789152	0.00131348465082953	0.0106690409674742
GO:0005085	guanyl-nucleotide exchange factor activity	73/4284	230/18639	0.317391304347826	1.38091888929485	0.00136241920188551	0.0109990428249781
GO:0101005	deubiquitinase activity	41/4284	115/18639	0.356521739130435	1.5511691633175	0.0013847537659416	0.0111115999157981
GO:1990841	promoter-specific chromatin binding	27/4284	68/18639	0.397058823529412	1.72753954522986	0.00147823458860181	0.0117902565982458
GO:0043022	ribosome binding	40/4284	112/18639	0.357142857142857	1.55387154861945	0.00151469375123746	0.0120087097403497
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	8/4284	12/18639	0.666666666666667	2.90056022408964	0.00154749158745758	0.0121957075106776
GO:0004659	prenyltransferase activity	10/4284	17/18639	0.588235294117647	2.55931784478497	0.00156313274029774	0.0122460813500249
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	31/4284	82/18639	0.378048780487805	1.64482988317278	0.001767067681997	0.0137623388880237
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	33/4284	89/18639	0.370786516853933	1.61323293362289	0.00186510034497902	0.0143569352136757
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	33/4284	89/18639	0.370786516853933	1.61323293362289	0.00186510034497902	0.0143569352136757
GO:0016279	protein-lysine N-methyltransferase activity	27/4284	69/18639	0.391304347826087	1.70250274022653	0.00190390137792414	0.014570898406772
GO:0046332	SMAD binding	30/4284	79/18639	0.379746835443038	1.65221784916498	0.00191620586221472	0.0145807848366224
GO:0004722	protein serine/threonine phosphatase activity	37/4284	103/18639	0.359223300970874	1.56292322754344	0.00198156920740062	0.0149919864605624
GO:0001217	DNA-binding transcription repressor activity	85/4284	278/18639	0.305755395683453	1.33029290853032	0.00201258181054442	0.0151289490178496
GO:0140296	general transcription initiation factor binding	22/4284	53/18639	0.415094339622642	1.80600919613128	0.0020225256617518	0.0151289490178496
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	31/4284	83/18639	0.373493975903614	1.62501265566468	0.00220877298372654	0.0164293001710896
GO:0140767	enzyme-substrate adaptor activity	47/4284	139/18639	0.338129496402878	1.47114745178647	0.00229985617875121	0.016955006122047
GO:0140793	histone H2AXY142 phosphatase activity	33/4284	90/18639	0.366666666666667	1.5953081232493	0.00230506125526319	0.016955006122047
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	82/4284	268/18639	0.305970149253731	1.33122726702621	0.00233448719765903	0.0170765803850859
GO:0140142	nucleocytoplasmic carrier activity	15/4284	32/18639	0.46875	2.03945640756303	0.00250532815327621	0.0181327846317419
GO:0140566	histone reader activity	16/4284	35/18639	0.457142857142857	1.98895558223289	0.00250626857070149	0.0181327846317419
GO:0016779	nucleotidyltransferase activity	46/4284	136/18639	0.338235294117647	1.47160776075136	0.00252492710881309	0.0181684972395029
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	22/4284	54/18639	0.407407407407407	1.77256458138811	0.00268212298260738	0.019195301778228
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	10/4284	18/18639	0.555555555555556	2.4171335200747	0.00279581662932854	0.0197949797712887
GO:0070628	proteasome binding	10/4284	18/18639	0.555555555555556	2.4171335200747	0.00279581662932854	0.0197949797712887
GO:0019903	protein phosphatase binding	48/4284	144/18639	0.333333333333333	1.45028011204482	0.0028833055927305	0.0200882284021762
GO:0003924	GTPase activity	98/4284	331/18639	0.29607250755287	1.2881642082815	0.00293961952362105	0.0200882284021762
GO:0033192	calmodulin-dependent protein phosphatase activity	30/4284	81/18639	0.37037037037037	1.61142234671646	0.00298895845561081	0.0200882284021762
GO:0140791	histone H2AXS140 phosphatase activity	30/4284	81/18639	0.37037037037037	1.61142234671646	0.00298895845561081	0.0200882284021762
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	30/4284	81/18639	0.37037037037037	1.61142234671646	0.00298895845561081	0.0200882284021762
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	30/4284	81/18639	0.37037037037037	1.61142234671646	0.00298895845561081	0.0200882284021762
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	30/4284	81/18639	0.37037037037037	1.61142234671646	0.00298895845561081	0.0200882284021762
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	30/4284	81/18639	0.37037037037037	1.61142234671646	0.00298895845561081	0.0200882284021762
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	30/4284	81/18639	0.37037037037037	1.61142234671646	0.00298895845561081	0.0200882284021762
GO:1990439	MAP kinase serine/threonine phosphatase activity	30/4284	81/18639	0.37037037037037	1.61142234671646	0.00298895845561081	0.0200882284021762
GO:0035613	RNA stem-loop binding	11/4284	21/18639	0.523809523809524	2.27901160464186	0.00319127396054365	0.021274407209164
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	8/4284	13/18639	0.615384615384615	2.67744020685197	0.00321365667812145	0.021274407209164
GO:0046975	histone H3K36 methyltransferase activity	8/4284	13/18639	0.615384615384615	2.67744020685197	0.00321365667812145	0.021274407209164
GO:0042578	phosphoric ester hydrolase activity	106/4284	363/18639	0.292011019283747	1.27049332129546	0.00330507745911195	0.0217707589843991
GO:0016741	transferase activity, transferring one-carbon groups	67/4284	215/18639	0.311627906976744	1.35584326753957	0.00342993723936268	0.0224813708164168
GO:0035035	histone acetyltransferase binding	12/4284	24/18639	0.5	2.17542016806723	0.00344847661904813	0.0224915420867967
GO:0000149	SNARE binding	37/4284	106/18639	0.349056603773585	1.51868955129221	0.00349159159392815	0.0226611140703965
GO:0031624	ubiquitin conjugating enzyme binding	14/4284	30/18639	0.466666666666667	2.03039215686275	0.00364441430549138	0.0235375831242468
GO:0033549	MAP kinase phosphatase activity	30/4284	82/18639	0.365853658536585	1.59177085468334	0.00369389544038802	0.0237413473935618
GO:0019208	phosphatase regulator activity	40/4284	117/18639	0.341880341880342	1.48746678158443	0.00374836872556177	0.0239750733944144
GO:0035091	phosphatidylinositol binding	85/4284	284/18639	0.299295774647887	1.30218812877264	0.00387167612216424	0.0246447076237762
GO:0008135	translation factor activity, RNA binding	30/4284	83/18639	0.36144578313253	1.57259289257872	0.00453453079321525	0.0287259271302249
GO:0032404	mismatch repair complex binding	7/4284	11/18639	0.636363636363636	2.76871657754011	0.00457099493324082	0.0288190347219564
GO:0003756	protein disulfide isomerase activity	10/4284	19/18639	0.526315789473684	2.28991596638655	0.00469531888548286	0.0291859258421564
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	10/4284	19/18639	0.526315789473684	2.28991596638655	0.00469531888548286	0.0291859258421564
GO:1990380	K48-linked deubiquitinase activity	10/4284	19/18639	0.526315789473684	2.28991596638655	0.00469531888548286	0.0291859258421564
GO:0061791	GTPase motor activity	17/4284	40/18639	0.425	1.84910714285714	0.00473949747579675	0.0291864867811856
GO:1990606	membrane scission GTPase motor activity	17/4284	40/18639	0.425	1.84910714285714	0.00473949747579675	0.0291864867811856
GO:0016860	intramolecular oxidoreductase activity	21/4284	53/18639	0.39622641509434	1.72391786903441	0.00489826476694113	0.0300245488492132
GO:0004843	cysteine-type deubiquitinase activity	37/4284	108/18639	0.342592592592593	1.49056567071273	0.00497095011715844	0.0303296679959345
GO:0140035	ubiquitin-like protein reader activity	11/4284	22/18639	0.5	2.17542016806723	0.00506906327025778	0.030786420962483
GO:0015035	protein-disulfide reductase activity	15/4284	34/18639	0.441176470588235	1.91948838358873	0.00513078835335628	0.0308780171811078
GO:0052866	phosphatidylinositol phosphate phosphatase activity	15/4284	34/18639	0.441176470588235	1.91948838358873	0.00513078835335628	0.0308780171811078
GO:0008139	nuclear localization sequence binding	12/4284	25/18639	0.48	2.08840336134454	0.00525929709027963	0.031246086437566
GO:0019211	phosphatase activator activity	12/4284	25/18639	0.48	2.08840336134454	0.00525929709027963	0.031246086437566
GO:0046966	nuclear thyroid hormone receptor binding	13/4284	28/18639	0.464285714285714	2.02003301320528	0.00530994671333258	0.031246086437566
GO:0051019	mitogen-activated protein kinase binding	13/4284	28/18639	0.464285714285714	2.02003301320528	0.00530994671333258	0.031246086437566
GO:0051537	2 iron, 2 sulfur cluster binding	13/4284	28/18639	0.464285714285714	2.02003301320528	0.00530994671333258	0.031246086437566
GO:0003724	RNA helicase activity	28/4284	77/18639	0.363636363636364	1.58212375859435	0.00543061105412291	0.0318147302462776
GO:0017018	myosin phosphatase activity	30/4284	84/18639	0.357142857142857	1.55387154861945	0.00553040478998503	0.0321151576400885
GO:0180051	translation factor activity	30/4284	84/18639	0.357142857142857	1.55387154861945	0.00553040478998503	0.0321151576400885
GO:0003678	DNA helicase activity	27/4284	74/18639	0.364864864864865	1.5874687712923	0.00594153808380664	0.0343519494452401
GO:0001046	core promoter sequence-specific DNA binding	18/4284	44/18639	0.409090909090909	1.77988922841864	0.00601145798815267	0.0346050885926701
GO:0019902	phosphatase binding	59/4284	190/18639	0.310526315789474	1.35105042016807	0.00624669780319163	0.0358035839455659
GO:0003925	G protein activity	21/4284	54/18639	0.388888888888889	1.69199346405229	0.00630853681151712	0.0360021669760719
GO:0004518	nuclease activity	64/4284	209/18639	0.30622009569378	1.33231474407945	0.00642324424238238	0.0364994651369711
GO:0003743	translation initiation factor activity	20/4284	51/18639	0.392156862745098	1.70621189652332	0.00681537196543755	0.0383980956691035
GO:0005048	signal sequence binding	20/4284	51/18639	0.392156862745098	1.70621189652332	0.00681537196543755	0.0383980956691035
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	9/4284	17/18639	0.529411764705882	2.30338606030648	0.00693273259562671	0.0388870632599813
GO:0140101	catalytic activity, acting on a tRNA	45/4284	139/18639	0.323741007194245	1.40854543256151	0.00696090180711146	0.0388870632599813
GO:0061608	nuclear import signal receptor activity	10/4284	20/18639	0.5	2.17542016806723	0.00747595759637975	0.0415889405781798
GO:0106222	lncRNA binding	13/4284	29/18639	0.448275862068966	1.9503767024051	0.00762702513973051	0.0422518045397623
GO:0008143	poly(A) binding	12/4284	26/18639	0.461538461538462	2.00808015513898	0.00775077692865034	0.0425810317573985
GO:0052742	phosphatidylinositol kinase activity	12/4284	26/18639	0.461538461538462	2.00808015513898	0.00775077692865034	0.0425810317573985
GO:0140313	molecular sequestering activity	21/4284	55/18639	0.381818181818182	1.66122994652406	0.00803460855819862	0.0439579410374173
GO:0008186	ATP-dependent activity, acting on RNA	28/4284	79/18639	0.354430379746835	1.54206999255398	0.00808279258814757	0.0440395777230756
GO:0043047	single-stranded telomeric DNA binding	7/4284	12/18639	0.583333333333333	2.53799019607843	0.00880389961733736	0.0468127031861633
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	7/4284	12/18639	0.583333333333333	2.53799019607843	0.00880389961733736	0.0468127031861633
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	7/4284	12/18639	0.583333333333333	2.53799019607843	0.00880389961733736	0.0468127031861633
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	7/4284	12/18639	0.583333333333333	2.53799019607843	0.00880389961733736	0.0468127031861633
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	7/4284	12/18639	0.583333333333333	2.53799019607843	0.00880389961733736	0.0468127031861633
GO:1990247	N6-methyladenosine-containing RNA reader activity	7/4284	12/18639	0.583333333333333	2.53799019607843	0.00880389961733736	0.0468127031861633
GO:0051536	iron-sulfur cluster binding	27/4284	76/18639	0.355263157894737	1.54569327731092	0.00887729991428787	0.0468268728546499
GO:0140034	methylation-dependent protein binding	27/4284	76/18639	0.355263157894737	1.54569327731092	0.00887729991428787	0.0468268728546499
GO:0005484	SNAP receptor activity	15/4284	36/18639	0.416666666666667	1.81285014005602	0.00962702778481335	0.0503801770240825
GO:0044390	ubiquitin-like protein conjugating enzyme binding	15/4284	36/18639	0.416666666666667	1.81285014005602	0.00962702778481335	0.0503801770240825
GO:0043539	protein serine/threonine kinase activator activity	26/4284	73/18639	0.356164383561644	1.54961436629446	0.00975078223749972	0.0508269121356285
GO:0042826	histone deacetylase binding	41/4284	127/18639	0.322834645669291	1.40460199827963	0.0101644497544943	0.0525530128340709
GO:0030291	protein serine/threonine kinase inhibitor activity	18/4284	46/18639	0.391304347826087	1.70250274022653	0.0102457112135655	0.0525530128340709
GO:0000774	adenyl-nucleotide exchange factor activity	8/4284	15/18639	0.533333333333333	2.32044817927171	0.010280385441106	0.0525530128340709
GO:0031386	protein tag activity	8/4284	15/18639	0.533333333333333	2.32044817927171	0.010280385441106	0.0525530128340709
GO:0141047	molecular tag activity	8/4284	15/18639	0.533333333333333	2.32044817927171	0.010280385441106	0.0525530128340709
GO:0035925	mRNA 3'-UTR AU-rich region binding	13/4284	30/18639	0.433333333333333	1.88536414565826	0.0106725510717957	0.054347913919452
GO:0051540	metal cluster binding	27/4284	77/18639	0.350649350649351	1.52561933864455	0.0107385118987769	0.0544742902451365
GO:0000900	mRNA regulatory element binding translation repressor activity	9/4284	18/18639	0.5	2.17542016806723	0.0110696485619249	0.0553489849716211
GO:1990381	ubiquitin-specific protease binding	9/4284	18/18639	0.5	2.17542016806723	0.0110696485619249	0.0553489849716211
GO:0048156	tau protein binding	17/4284	43/18639	0.395348837209302	1.72009966777409	0.0110699408158143	0.0553489849716211
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	12/4284	27/18639	0.444444444444444	1.93370681605976	0.011078157868187	0.0553489849716211
GO:0140033	acetylation-dependent protein binding	11/4284	24/18639	0.458333333333333	1.99413515406162	0.0113371784847103	0.0562275071887011
GO:0051010	microtubule plus-end binding	10/4284	21/18639	0.476190476190476	2.0718287314926	0.011371124538049	0.0562275071887011
GO:0016853	isomerase activity	55/4284	180/18639	0.305555555555556	1.32942343604108	0.0113813987360815	0.0562275071887011
GO:0004197	cysteine-type endopeptidase activity	30/4284	88/18639	0.340909090909091	1.4832410236822	0.0115122309824826	0.0566624305606205
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	16/4284	40/18639	0.4	1.74033613445378	0.0119296191852347	0.0584993177824099
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	6/4284	10/18639	0.6	2.61050420168067	0.0129490123219261	0.0623436084153824
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	6/4284	10/18639	0.6	2.61050420168067	0.0129490123219261	0.0623436084153824
GO:0098505	G-rich strand telomeric DNA binding	6/4284	10/18639	0.6	2.61050420168067	0.0129490123219261	0.0623436084153824
GO:0099122	RNA polymerase II C-terminal domain binding	6/4284	10/18639	0.6	2.61050420168067	0.0129490123219261	0.0623436084153824
GO:1905394	retromer complex binding	6/4284	10/18639	0.6	2.61050420168067	0.0129490123219261	0.0623436084153824
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	39/4284	122/18639	0.319672131147541	1.39084240253478	0.014156217076688	0.0679088094548368
GO:0030145	manganese ion binding	24/4284	68/18639	0.352941176470588	1.53559070687098	0.0143084453731753	0.0681452578204464
GO:0140223	general transcription initiation factor activity	24/4284	68/18639	0.352941176470588	1.53559070687098	0.0143084453731753	0.0681452578204464
GO:0051219	phosphoprotein binding	31/4284	93/18639	0.333333333333333	1.45028011204482	0.0145608315844124	0.0690987133253121
GO:0051011	microtubule minus-end binding	7/4284	13/18639	0.538461538461538	2.34276018099548	0.0153258497130893	0.0710638142656793
GO:0097157	pre-mRNA intronic binding	7/4284	13/18639	0.538461538461538	2.34276018099548	0.0153258497130893	0.0710638142656793
GO:0140666	annealing activity	7/4284	13/18639	0.538461538461538	2.34276018099548	0.0153258497130893	0.0710638142656793
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	7/4284	13/18639	0.538461538461538	2.34276018099548	0.0153258497130893	0.0710638142656793
GO:0019789	SUMO transferase activity	12/4284	28/18639	0.428571428571429	1.86464585834334	0.0154043162343278	0.0710638142656793
GO:0046875	ephrin receptor binding	12/4284	28/18639	0.428571428571429	1.86464585834334	0.0154043162343278	0.0710638142656793
GO:0097718	disordered domain specific binding	12/4284	28/18639	0.428571428571429	1.86464585834334	0.0154043162343278	0.0710638142656793
GO:0141052	histone H3 demethylase activity	12/4284	28/18639	0.428571428571429	1.86464585834334	0.0154043162343278	0.0710638142656793
GO:0061980	regulatory RNA binding	21/4284	58/18639	0.362068965517241	1.57530425963489	0.0156047031569767	0.0717382881244346
GO:0000062	fatty-acyl-CoA binding	8/4284	16/18639	0.5	2.17542016806723	0.0164707676217595	0.0751148230506477
GO:0005521	lamin binding	8/4284	16/18639	0.5	2.17542016806723	0.0164707676217595	0.0751148230506477
GO:0140693	molecular condensate scaffold activity	18/4284	48/18639	0.375	1.63156512605042	0.0165655808874916	0.0751148230506477
GO:0008017	microtubule binding	79/4284	276/18639	0.286231884057971	1.24534922664718	0.0165870172705296	0.0751148230506477
GO:0050321	tau-protein kinase activity	10/4284	22/18639	0.454545454545455	1.97765469824293	0.0166228422612083	0.0751148230506477
GO:0043531	ADP binding	15/4284	38/18639	0.394736842105263	1.71743697478992	0.0167649070447996	0.0751752227649898
GO:0120227	acyl-CoA binding	9/4284	19/18639	0.473684210526316	2.0609243697479	0.0168065452707228	0.0751752227649898
GO:0140036	ubiquitin-modified protein reader activity	9/4284	19/18639	0.473684210526316	2.0609243697479	0.0168065452707228	0.0751752227649898
GO:0043015	gamma-tubulin binding	14/4284	35/18639	0.4	1.74033613445378	0.0181127879925594	0.0807452232395576
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	131/4284	484/18639	0.270661157024793	1.17760347940829	0.0188229048883388	0.083629282121344
GO:0031593	polyubiquitin modification-dependent protein binding	21/4284	59/18639	0.355932203389831	1.54860418743769	0.0191029575718523	0.0845896850338879
GO:0035198	miRNA binding	16/4284	42/18639	0.380952380952381	1.65746298519408	0.0197835057624933	0.0873112054318038
GO:0016763	pentosyltransferase activity	18/4284	49/18639	0.36734693877551	1.59826787858	0.0206895496704924	0.091006524132
GO:0016776	phosphotransferase activity, phosphate group as acceptor	15/4284	39/18639	0.384615384615385	1.67340012928248	0.0215844923843871	0.0946287017116838
GO:0035591	signaling adaptor activity	40/4284	129/18639	0.310077519379845	1.34909777864634	0.0218436259605693	0.0954487154184614
GO:0034237	protein kinase A regulatory subunit binding	11/4284	26/18639	0.423076923076923	1.84074014221073	0.022244701905855	0.0958193171976929
GO:0050681	nuclear androgen receptor binding	11/4284	26/18639	0.423076923076923	1.84074014221073	0.022244701905855	0.0958193171976929
GO:0097602	cullin family protein binding	11/4284	26/18639	0.423076923076923	1.84074014221073	0.022244701905855	0.0958193171976929
GO:0035064	methylated histone binding	25/4284	74/18639	0.337837837837838	1.46987849193732	0.0222817319443719	0.0958193171976929
GO:0019209	kinase activator activity	45/4284	148/18639	0.304054054054054	1.32289064274358	0.022290294332998	0.0958193171976929
GO:0001216	DNA-binding transcription activator activity	132/4284	491/18639	0.268839103869654	1.16967601704633	0.0227071657025288	0.0972954284470811
GO:0042054	histone methyltransferase activity	23/4284	67/18639	0.343283582089552	1.49357205568795	0.0228446764178136	0.0973018732951225
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	6/4284	11/18639	0.545454545454545	2.37318563789152	0.0230026331883485	0.0973018732951225
GO:0019107	myristoyltransferase activity	6/4284	11/18639	0.545454545454545	2.37318563789152	0.0230026331883485	0.0973018732951225
GO:0180030	inositol phosphate kinase activity	6/4284	11/18639	0.545454545454545	2.37318563789152	0.0230026331883485	0.0973018732951225
GO:0098531	ligand-modulated transcription factor activity	21/4284	60/18639	0.35	1.52279411764706	0.0231809377532007	0.0977438267045787
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	10/4284	23/18639	0.434782608695652	1.89166971136281	0.0234700105675619	0.0978961320551818
GO:0070577	lysine-acetylated histone binding	10/4284	23/18639	0.434782608695652	1.89166971136281	0.0234700105675619	0.0978961320551818
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	10/4284	23/18639	0.434782608695652	1.89166971136281	0.0234700105675619	0.0978961320551818
GO:0055106	ubiquitin-protein transferase regulator activity	14/4284	36/18639	0.388888888888889	1.69199346405229	0.0235128172156705	0.0978961320551818
GO:0043024	ribosomal small subunit binding	9/4284	20/18639	0.45	1.9578781512605	0.0244406624588215	0.10144024167862
GO:0070742	C2H2 zinc finger domain binding	7/4284	14/18639	0.5	2.17542016806723	0.0246567773335528	0.101488554044599
GO:0098847	sequence-specific single stranded DNA binding	7/4284	14/18639	0.5	2.17542016806723	0.0246567773335528	0.101488554044599
GO:0017124	SH3 domain binding	36/4284	115/18639	0.31304347826087	1.36200219218122	0.0246822616332031	0.101488554044599
GO:0070403	NAD+ binding	8/4284	17/18639	0.470588235294118	2.04745427582798	0.0249490209783219	0.101952172145982
GO:1901567	fatty acid derivative binding	8/4284	17/18639	0.470588235294118	2.04745427582798	0.0249490209783219	0.101952172145982
GO:0032451	demethylase activity	15/4284	40/18639	0.375	1.63156512605042	0.0273774163038786	0.111531382111801
GO:0008187	poly-pyrimidine tract binding	12/4284	30/18639	0.4	1.74033613445378	0.0277085805716206	0.112190093812922
GO:0032452	histone demethylase activity	12/4284	30/18639	0.4	1.74033613445378	0.0277085805716206	0.112190093812922
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	21/4284	61/18639	0.344262295081967	1.49783027965284	0.0278943532445767	0.112597938097011
GO:0140938	histone H3 methyltransferase activity	17/4284	47/18639	0.361702127659574	1.57370820668693	0.0281698003478257	0.113067548519352
GO:0017069	snRNA binding	19/4284	54/18639	0.351851851851852	1.53085122938064	0.0282668871298381	0.113067548519352
GO:0051287	NAD binding	19/4284	54/18639	0.351851851851852	1.53085122938064	0.0282668871298381	0.113067548519352
GO:0008266	poly(U) RNA binding	11/4284	27/18639	0.407407407407407	1.77256458138811	0.0299217009317518	0.119326301306143
GO:0017116	single-stranded DNA helicase activity	20/4284	58/18639	0.344827586206897	1.50028977108085	0.0308488554278032	0.122654308067302
GO:0000049	tRNA binding	26/4284	80/18639	0.325	1.4140231092437	0.0325922659278428	0.129198084097197
GO:0004540	RNA nuclease activity	37/4284	121/18639	0.305785123966942	1.33042225154525	0.032728849336498	0.129352228422458
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9/4284	21/18639	0.428571428571429	1.86464585834334	0.034242815899401	0.134933000746449
GO:0070273	phosphatidylinositol-4-phosphate binding	12/4284	31/18639	0.387096774193548	1.68419625914882	0.0359981367265876	0.141010452739651
GO:0140457	protein demethylase activity	12/4284	31/18639	0.387096774193548	1.68419625914882	0.0359981367265876	0.141010452739651
GO:0004879	nuclear receptor activity	20/4284	59/18639	0.338983050847458	1.47486113089304	0.0368723927898292	0.141262530650497
GO:0045309	protein phosphorylated amino acid binding	20/4284	59/18639	0.338983050847458	1.47486113089304	0.0368723927898292	0.141262530650497
GO:0034452	dynactin binding	6/4284	12/18639	0.5	2.17542016806723	0.0372013667593595	0.141262530650497
GO:0035497	cAMP response element binding	6/4284	12/18639	0.5	2.17542016806723	0.0372013667593595	0.141262530650497
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	6/4284	12/18639	0.5	2.17542016806723	0.0372013667593595	0.141262530650497
GO:0004559	alpha-mannosidase activity	7/4284	15/18639	0.466666666666667	2.03039215686275	0.0372361202394436	0.141262530650497
GO:0042809	nuclear vitamin D receptor binding	7/4284	15/18639	0.466666666666667	2.03039215686275	0.0372361202394436	0.141262530650497
GO:0050700	CARD domain binding	7/4284	15/18639	0.466666666666667	2.03039215686275	0.0372361202394436	0.141262530650497
GO:0061578	K63-linked deubiquitinase activity	7/4284	15/18639	0.466666666666667	2.03039215686275	0.0372361202394436	0.141262530650497
GO:0120283	protein serine/threonine kinase binding	7/4284	15/18639	0.466666666666667	2.03039215686275	0.0372361202394436	0.141262530650497
GO:0140776	protein-containing complex destabilizing activity	7/4284	15/18639	0.466666666666667	2.03039215686275	0.0372361202394436	0.141262530650497
GO:0042162	telomeric DNA binding	14/4284	38/18639	0.368421052631579	1.60294117647059	0.0377600140475321	0.142840738854093
GO:0003684	damaged DNA binding	24/4284	74/18639	0.324324324324324	1.41108335225982	0.0398579779681432	0.150347472449634
GO:0051879	Hsp90 protein binding	15/4284	42/18639	0.357142857142857	1.55387154861945	0.042277616422586	0.159021489044045
GO:0017056	structural constituent of nuclear pore	10/4284	25/18639	0.4	1.74033613445378	0.0428187608481562	0.160147003850166
GO:0042974	nuclear retinoic acid receptor binding	10/4284	25/18639	0.4	1.74033613445378	0.0428187608481562	0.160147003850166
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	20/4284	60/18639	0.333333333333333	1.45028011204482	0.0437181203081435	0.163050116304175
GO:0016251	RNA polymerase II general transcription initiation factor activity	18/4284	53/18639	0.339622641509434	1.47764388774378	0.0453160273172576	0.168062801591174
GO:0051018	protein kinase A binding	18/4284	53/18639	0.339622641509434	1.47764388774378	0.0453160273172576	0.168062801591174
GO:0030515	snoRNA binding	12/4284	32/18639	0.375	1.63156512605042	0.0458971355125019	0.169742478822772
GO:0004536	DNA nuclease activity	21/4284	64/18639	0.328125	1.42761948529412	0.0463822633792298	0.171058820930641
GO:0050145	nucleoside monophosphate kinase activity	8/4284	19/18639	0.421052631578947	1.83193277310924	0.0500495906501428	0.18407127227997
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	11/4284	29/18639	0.379310344827586	1.65031874818893	0.0505726624755744	0.184967417452101
GO:0097472	cyclin-dependent protein kinase activity	11/4284	29/18639	0.379310344827586	1.65031874818893	0.0505726624755744	0.184967417452101
GO:0005159	insulin-like growth factor receptor binding	7/4284	16/18639	0.4375	1.90349264705882	0.0533869500531981	0.191556427833155
GO:0015923	mannosidase activity	7/4284	16/18639	0.4375	1.90349264705882	0.0533869500531981	0.191556427833155
GO:0017070	U6 snRNA binding	7/4284	16/18639	0.4375	1.90349264705882	0.0533869500531981	0.191556427833155
GO:0031435	mitogen-activated protein kinase kinase kinase binding	7/4284	16/18639	0.4375	1.90349264705882	0.0533869500531981	0.191556427833155
GO:0043023	ribosomal large subunit binding	7/4284	16/18639	0.4375	1.90349264705882	0.0533869500531981	0.191556427833155
GO:0070411	I-SMAD binding	7/4284	16/18639	0.4375	1.90349264705882	0.0533869500531981	0.191556427833155
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	7/4284	16/18639	0.4375	1.90349264705882	0.0533869500531981	0.191556427833155
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	10/4284	26/18639	0.384615384615385	1.67340012928248	0.0556775476870942	0.196070670195289
GO:0030507	spectrin binding	10/4284	26/18639	0.384615384615385	1.67340012928248	0.0556775476870942	0.196070670195289
GO:0070006	metalloaminopeptidase activity	10/4284	26/18639	0.384615384615385	1.67340012928248	0.0556775476870942	0.196070670195289
GO:1990518	single-stranded 3'-5' DNA helicase activity	16/4284	47/18639	0.340425531914894	1.48113713570535	0.0558905430051935	0.196070670195289
GO:0008253	5'-nucleotidase activity	6/4284	13/18639	0.461538461538462	2.00808015513898	0.0559518099418769	0.196070670195289
GO:0046974	histone H3K9 methyltransferase activity	6/4284	13/18639	0.461538461538462	2.00808015513898	0.0559518099418769	0.196070670195289
GO:0005528	FK506 binding	5/4284	10/18639	0.5	2.17542016806723	0.0567183283117792	0.196070670195289
GO:0008140	cAMP response element binding protein binding	5/4284	10/18639	0.5	2.17542016806723	0.0567183283117792	0.196070670195289
GO:0008641	ubiquitin-like modifier activating enzyme activity	5/4284	10/18639	0.5	2.17542016806723	0.0567183283117792	0.196070670195289
GO:0015924	mannosyl-oligosaccharide mannosidase activity	5/4284	10/18639	0.5	2.17542016806723	0.0567183283117792	0.196070670195289
GO:0016783	sulfurtransferase activity	5/4284	10/18639	0.5	2.17542016806723	0.0567183283117792	0.196070670195289
GO:0043422	protein kinase B binding	5/4284	10/18639	0.5	2.17542016806723	0.0567183283117792	0.196070670195289
GO:0045322	unmethylated CpG binding	5/4284	10/18639	0.5	2.17542016806723	0.0567183283117792	0.196070670195289
GO:0050815	phosphoserine residue binding	5/4284	10/18639	0.5	2.17542016806723	0.0567183283117792	0.196070670195289
GO:0051117	ATPase binding	26/4284	84/18639	0.30952380952381	1.34668867547019	0.0571549694272802	0.197005964697851
GO:0030331	nuclear estrogen receptor binding	14/4284	40/18639	0.35	1.52279411764706	0.057286477650055	0.197005964697851
GO:0019888	protein phosphatase regulator activity	32/4284	107/18639	0.299065420560748	1.30118589491871	0.0587944051581904	0.201667856034829
GO:0005158	insulin receptor binding	9/4284	23/18639	0.391304347826087	1.70250274022653	0.0612084904429783	0.209405791593032
GO:0001223	transcription coactivator binding	15/4284	44/18639	0.340909090909091	1.4832410236822	0.0621678045386605	0.212139621673161
GO:0051721	protein phosphatase 2A binding	11/4284	30/18639	0.366666666666667	1.5953081232493	0.0638097625252321	0.217182842116728
GO:0030295	protein kinase activator activity	40/4284	139/18639	0.287769784172662	1.25204038449912	0.0658460437539936	0.223538876744327
GO:0036121	double-stranded DNA helicase activity	16/4284	48/18639	0.333333333333333	1.45028011204482	0.0665691122237859	0.224692726012072
GO:0043138	3'-5' DNA helicase activity	16/4284	48/18639	0.333333333333333	1.45028011204482	0.0665691122237859	0.224692726012072
GO:0036002	pre-mRNA binding	19/4284	59/18639	0.322033898305085	1.40111807434838	0.0666950463162721	0.224692726012072
GO:0052745	inositol phosphate phosphatase activity	8/4284	20/18639	0.4	1.74033613445378	0.0671222094443569	0.225557881483067
GO:0001727	lipid kinase activity	14/4284	41/18639	0.341463414634146	1.48565279770445	0.0692344261865378	0.232066785496142
GO:0008173	RNA methyltransferase activity	21/4284	67/18639	0.313432835820896	1.36369622475856	0.0723788306803396	0.241394513773705
GO:0005092	GDP-dissociation inhibitor activity	7/4284	17/18639	0.411764705882353	1.79152249134948	0.0732935004056114	0.241394513773705
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	7/4284	17/18639	0.411764705882353	1.79152249134948	0.0732935004056114	0.241394513773705
GO:0016805	dipeptidase activity	7/4284	17/18639	0.411764705882353	1.79152249134948	0.0732935004056114	0.241394513773705
GO:0046965	nuclear retinoid X receptor binding	7/4284	17/18639	0.411764705882353	1.79152249134948	0.0732935004056114	0.241394513773705
GO:0051787	misfolded protein binding	7/4284	17/18639	0.411764705882353	1.79152249134948	0.0732935004056114	0.241394513773705
GO:1990226	histone methyltransferase binding	7/4284	17/18639	0.411764705882353	1.79152249134948	0.0732935004056114	0.241394513773705
GO:0001091	RNA polymerase II general transcription initiation factor binding	9/4284	24/18639	0.375	1.63156512605042	0.0786517931898631	0.257759837087571
GO:0048027	mRNA 5'-UTR binding	9/4284	24/18639	0.375	1.63156512605042	0.0786517931898631	0.257759837087571
GO:0005545	1-phosphatidylinositol binding	6/4284	14/18639	0.428571428571429	1.86464585834334	0.0794230843981198	0.258368952685775
GO:0030983	mismatched DNA binding	6/4284	14/18639	0.428571428571429	1.86464585834334	0.0794230843981198	0.258368952685775
GO:0061665	SUMO ligase activity	6/4284	14/18639	0.428571428571429	1.86464585834334	0.0794230843981198	0.258368952685775
GO:1901981	phosphatidylinositol phosphate binding	51/4284	185/18639	0.275675675675676	1.19942084942085	0.0825398936583359	0.26710192276759
GO:0004520	DNA endonuclease activity	14/4284	42/18639	0.333333333333333	1.45028011204482	0.0827128310685134	0.26710192276759
GO:0048487	beta-tubulin binding	14/4284	42/18639	0.333333333333333	1.45028011204482	0.0827128310685134	0.26710192276759
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	5/4284	11/18639	0.454545454545455	1.97765469824293	0.0848147409146384	0.270589679448148
GO:0005225	volume-sensitive anion channel activity	5/4284	11/18639	0.454545454545455	1.97765469824293	0.0848147409146384	0.270589679448148
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	5/4284	11/18639	0.454545454545455	1.97765469824293	0.0848147409146384	0.270589679448148
GO:0034713	type I transforming growth factor beta receptor binding	5/4284	11/18639	0.454545454545455	1.97765469824293	0.0848147409146384	0.270589679448148
GO:0140031	phosphorylation-dependent protein binding	5/4284	11/18639	0.454545454545455	1.97765469824293	0.0848147409146384	0.270589679448148
GO:0005154	epidermal growth factor receptor binding	12/4284	35/18639	0.342857142857143	1.49171668667467	0.0862408123253205	0.274477969996934
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	8/4284	21/18639	0.380952380952381	1.65746298519408	0.0873556823950989	0.276695989213184
GO:0072542	protein phosphatase activator activity	8/4284	21/18639	0.380952380952381	1.65746298519408	0.0873556823950989	0.276695989213184
GO:0015605	organophosphate ester transmembrane transporter activity	16/4284	50/18639	0.32	1.39226890756303	0.0918223102782434	0.290149734626239
GO:0008308	voltage-gated monoatomic anion channel activity	7/4284	18/18639	0.388888888888889	1.69199346405229	0.0969923068109935	0.303588213280746
GO:0008409	5'-3' exonuclease activity	7/4284	18/18639	0.388888888888889	1.69199346405229	0.0969923068109935	0.303588213280746
GO:0017075	syntaxin-1 binding	7/4284	18/18639	0.388888888888889	1.69199346405229	0.0969923068109935	0.303588213280746
GO:0017128	phospholipid scramblase activity	7/4284	18/18639	0.388888888888889	1.69199346405229	0.0969923068109935	0.303588213280746
GO:0004712	protein serine/threonine/tyrosine kinase activity	14/4284	43/18639	0.325581395348837	1.41655266757866	0.0977512493585434	0.305242108846018
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	9/4284	25/18639	0.36	1.5663025210084	0.0988078738820732	0.307447515044244
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	18/4284	58/18639	0.310344827586207	1.35026079397276	0.0989219345988279	0.307447515044244
GO:0031490	chromatin DNA binding	36/4284	128/18639	0.28125	1.22367384453782	0.101769854466299	0.315558049914237
GO:0061749	forked DNA-dependent helicase activity	15/4284	47/18639	0.319148936170213	1.38856606472376	0.10239697517012	0.316760736273921
GO:0008252	nucleotidase activity	6/4284	15/18639	0.4	1.74033613445378	0.107547727170571	0.33114695528799
GO:0055105	ubiquitin-protein transferase inhibitor activity	6/4284	15/18639	0.4	1.74033613445378	0.107547727170571	0.33114695528799
GO:0004177	aminopeptidase activity	13/4284	40/18639	0.325	1.4140231092437	0.109316422588018	0.335034591450315
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	13/4284	40/18639	0.325	1.4140231092437	0.109316422588018	0.335034591450315
GO:0034062	5'-3' RNA polymerase activity	8/4284	22/18639	0.363636363636364	1.58212375859435	0.11073535279951	0.337042774957588
GO:0070034	telomerase RNA binding	8/4284	22/18639	0.363636363636364	1.58212375859435	0.11073535279951	0.337042774957588
GO:0097747	RNA polymerase activity	8/4284	22/18639	0.363636363636364	1.58212375859435	0.11073535279951	0.337042774957588
GO:0005543	phospholipid binding	126/4284	497/18639	0.253521126760563	1.10302994437211	0.112426452528203	0.341405098961791
GO:0071889	14-3-3 protein binding	11/4284	33/18639	0.333333333333333	1.45028011204482	0.115992972457426	0.351429509230281
GO:0009378	four-way junction helicase activity	15/4284	48/18639	0.3125	1.35963760504202	0.118682367418453	0.352742971077775
GO:0032266	phosphatidylinositol-3-phosphate binding	15/4284	48/18639	0.3125	1.35963760504202	0.118682367418453	0.352742971077775
GO:0004300	enoyl-CoA hydratase activity	5/4284	12/18639	0.416666666666667	1.81285014005602	0.118824293882694	0.352742971077775
GO:0005049	nuclear export signal receptor activity	5/4284	12/18639	0.416666666666667	1.81285014005602	0.118824293882694	0.352742971077775
GO:0005527	macrolide binding	5/4284	12/18639	0.416666666666667	1.81285014005602	0.118824293882694	0.352742971077775
GO:0016801	hydrolase activity, acting on ether bonds	5/4284	12/18639	0.416666666666667	1.81285014005602	0.118824293882694	0.352742971077775
GO:0016803	ether hydrolase activity	5/4284	12/18639	0.416666666666667	1.81285014005602	0.118824293882694	0.352742971077775
GO:0017166	vinculin binding	5/4284	12/18639	0.416666666666667	1.81285014005602	0.118824293882694	0.352742971077775
GO:1990459	transferrin receptor binding	5/4284	12/18639	0.416666666666667	1.81285014005602	0.118824293882694	0.352742971077775
GO:0004529	DNA exonuclease activity	9/4284	26/18639	0.346153846153846	1.50606011635423	0.121641575985297	0.357896548010074
GO:0005160	transforming growth factor beta receptor binding	9/4284	26/18639	0.346153846153846	1.50606011635423	0.121641575985297	0.357896548010074
GO:0050750	low-density lipoprotein particle receptor binding	9/4284	26/18639	0.346153846153846	1.50606011635423	0.121641575985297	0.357896548010074
GO:0070412	R-SMAD binding	9/4284	26/18639	0.346153846153846	1.50606011635423	0.121641575985297	0.357896548010074
GO:0005346	purine ribonucleotide transmembrane transporter activity	7/4284	19/18639	0.368421052631579	1.60294117647059	0.124375557904823	0.364321324482269
GO:0097001	ceramide binding	7/4284	19/18639	0.368421052631579	1.60294117647059	0.124375557904823	0.364321324482269
GO:0015215	nucleotide transmembrane transporter activity	10/4284	30/18639	0.333333333333333	1.45028011204482	0.13041027714101	0.380315433776867
GO:0070566	adenylyltransferase activity	10/4284	30/18639	0.333333333333333	1.45028011204482	0.13041027714101	0.380315433776867
GO:0051539	4 iron, 4 sulfur cluster binding	14/4284	45/18639	0.311111111111111	1.35359477124183	0.132513861441707	0.38560077483257
GO:0005548	phospholipid transporter activity	20/4284	68/18639	0.294117647058824	1.27965892239249	0.132833962607458	0.385684575640953
GO:0008175	tRNA methyltransferase activity	11/4284	34/18639	0.323529411764706	1.40762481463174	0.137536558421685	0.398464777571795
GO:0003688	DNA replication origin binding	6/4284	16/18639	0.375	1.63156512605042	0.140044193440995	0.402209353830535
GO:0008296	3'-5'-DNA exonuclease activity	6/4284	16/18639	0.375	1.63156512605042	0.140044193440995	0.402209353830535
GO:0034450	ubiquitin-ubiquitin ligase activity	6/4284	16/18639	0.375	1.63156512605042	0.140044193440995	0.402209353830535
GO:0097027	ubiquitin-protein transferase activator activity	6/4284	16/18639	0.375	1.63156512605042	0.140044193440995	0.402209353830535
GO:0016504	peptidase activator activity	17/4284	57/18639	0.298245614035088	1.29761904761905	0.14247405714801	0.408302276328929
GO:0035255	ionotropic glutamate receptor binding	9/4284	27/18639	0.333333333333333	1.45028011204482	0.14704834108871	0.420501087692122
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	14/4284	46/18639	0.304347826086957	1.32416879795396	0.152183583463874	0.434247983849501
GO:0051213	dioxygenase activity	26/4284	93/18639	0.279569892473118	1.21636396494081	0.154069136630595	0.435361169522394
GO:0070325	lipoprotein particle receptor binding	10/4284	31/18639	0.32258064516129	1.40349688262402	0.15484081067745	0.435361169522394
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	7/4284	20/18639	0.35	1.52279411764706	0.15520428399892	0.435361169522394
GO:0015095	magnesium ion transmembrane transporter activity	7/4284	20/18639	0.35	1.52279411764706	0.15520428399892	0.435361169522394
GO:0016505	peptidase activator activity involved in apoptotic process	7/4284	20/18639	0.35	1.52279411764706	0.15520428399892	0.435361169522394
GO:0030742	GTP-dependent protein binding	7/4284	20/18639	0.35	1.52279411764706	0.15520428399892	0.435361169522394
GO:0140664	ATP-dependent DNA damage sensor activity	7/4284	20/18639	0.35	1.52279411764706	0.15520428399892	0.435361169522394
GO:0140939	histone H4 methyltransferase activity	7/4284	20/18639	0.35	1.52279411764706	0.15520428399892	0.435361169522394
GO:0005338	nucleotide-sugar transmembrane transporter activity	5/4284	13/18639	0.384615384615385	1.67340012928248	0.158119596345706	0.441667395699819
GO:0035673	oligopeptide transmembrane transporter activity	5/4284	13/18639	0.384615384615385	1.67340012928248	0.158119596345706	0.441667395699819
GO:0000217	DNA secondary structure binding	12/4284	39/18639	0.307692307692308	1.33872010342599	0.166030524085705	0.461869551732021
GO:0031491	nucleosome binding	21/4284	74/18639	0.283783783783784	1.23469793322734	0.166254066348479	0.461869551732021
GO:0140612	DNA damage sensor activity	8/4284	24/18639	0.333333333333333	1.45028011204482	0.166398622489558	0.461869551732021
GO:0008375	acetylglucosaminyltransferase activity	13/4284	43/18639	0.302325581395349	1.31537033418018	0.170052321380612	0.471023584744623
GO:0001784	phosphotyrosine residue binding	14/4284	47/18639	0.297872340425532	1.29599499374218	0.173305174861224	0.479031422789688
GO:0046625	sphingolipid binding	9/4284	28/18639	0.321428571428571	1.3984843937575	0.174859864397854	0.482321792630747
GO:0032183	SUMO binding	6/4284	17/18639	0.352941176470588	1.53559070687098	0.176453662369385	0.482707030565255
GO:0005381	iron ion transmembrane transporter activity	4/4284	10/18639	0.4	1.74033613445378	0.179009933540438	0.482707030565255
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	4/4284	10/18639	0.4	1.74033613445378	0.179009933540438	0.482707030565255
GO:0015279	store-operated calcium channel activity	4/4284	10/18639	0.4	1.74033613445378	0.179009933540438	0.482707030565255
GO:0016427	tRNA (cytidine) methyltransferase activity	4/4284	10/18639	0.4	1.74033613445378	0.179009933540438	0.482707030565255
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	4/4284	10/18639	0.4	1.74033613445378	0.179009933540438	0.482707030565255
GO:0031434	mitogen-activated protein kinase kinase binding	4/4284	10/18639	0.4	1.74033613445378	0.179009933540438	0.482707030565255
GO:0031996	thioesterase binding	4/4284	10/18639	0.4	1.74033613445378	0.179009933540438	0.482707030565255
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	4/4284	10/18639	0.4	1.74033613445378	0.179009933540438	0.482707030565255
GO:0140999	histone H3K4 trimethyltransferase activity	4/4284	10/18639	0.4	1.74033613445378	0.179009933540438	0.482707030565255
GO:1990757	ubiquitin ligase activator activity	4/4284	10/18639	0.4	1.74033613445378	0.179009933540438	0.482707030565255
GO:0031369	translation initiation factor binding	10/4284	32/18639	0.3125	1.35963760504202	0.181358743577892	0.488046700197416
GO:0030165	PDZ domain binding	23/4284	83/18639	0.27710843373494	1.20565455097702	0.18403305086444	0.494238862767786
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	11/4284	36/18639	0.305555555555556	1.32942343604108	0.186401955779493	0.497572962604937
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	11/4284	36/18639	0.305555555555556	1.32942343604108	0.186401955779493	0.497572962604937
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	11/4284	36/18639	0.305555555555556	1.32942343604108	0.186401955779493	0.497572962604937
GO:0010314	phosphatidylinositol-5-phosphate binding	7/4284	21/18639	0.333333333333333	1.45028011204482	0.18912858480083	0.503835505586116
GO:0044325	transmembrane transporter binding	36/4284	136/18639	0.264705882352941	1.15169303015324	0.191516872688783	0.509173372369374
GO:0004709	MAP kinase kinase kinase activity	8/4284	25/18639	0.32	1.39226890756303	0.198206033598961	0.52484957697005
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	8/4284	25/18639	0.32	1.39226890756303	0.198206033598961	0.52484957697005
GO:0016651	oxidoreductase activity, acting on NAD(P)H	24/4284	88/18639	0.272727272727273	1.18659281894576	0.200831341393352	0.525021615181935
GO:0032934	sterol binding	19/4284	68/18639	0.279411764705882	1.21567597627286	0.20122210023418	0.525021615181935
GO:0005347	ATP transmembrane transporter activity	5/4284	14/18639	0.357142857142857	1.55387154861945	0.201839880761031	0.525021615181935
GO:0008174	mRNA methyltransferase activity	5/4284	14/18639	0.357142857142857	1.55387154861945	0.201839880761031	0.525021615181935
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	5/4284	14/18639	0.357142857142857	1.55387154861945	0.201839880761031	0.525021615181935
GO:0019992	diacylglycerol binding	5/4284	14/18639	0.357142857142857	1.55387154861945	0.201839880761031	0.525021615181935
GO:0032454	histone H3K9 demethylase activity	5/4284	14/18639	0.357142857142857	1.55387154861945	0.201839880761031	0.525021615181935
GO:0046030	inositol trisphosphate phosphatase activity	5/4284	14/18639	0.357142857142857	1.55387154861945	0.201839880761031	0.525021615181935
GO:0071933	Arp2/3 complex binding	5/4284	14/18639	0.357142857142857	1.55387154861945	0.201839880761031	0.525021615181935
GO:0008137	NADH dehydrogenase (ubiquinone) activity	12/4284	41/18639	0.292682926829268	1.27341668374667	0.216161662757446	0.553632623513967
GO:0016877	ligase activity, forming carbon-sulfur bonds	12/4284	41/18639	0.292682926829268	1.27341668374667	0.216161662757446	0.553632623513967
GO:0140318	protein transporter activity	12/4284	41/18639	0.292682926829268	1.27341668374667	0.216161662757446	0.553632623513967
GO:0000400	four-way junction DNA binding	6/4284	18/18639	0.333333333333333	1.45028011204482	0.216184340148581	0.553632623513967
GO:0004706	JUN kinase kinase kinase activity	6/4284	18/18639	0.333333333333333	1.45028011204482	0.216184340148581	0.553632623513967
GO:0031690	adrenergic receptor binding	6/4284	18/18639	0.333333333333333	1.45028011204482	0.216184340148581	0.553632623513967
GO:0070064	proline-rich region binding	6/4284	18/18639	0.333333333333333	1.45028011204482	0.216184340148581	0.553632623513967
GO:0098641	cadherin binding involved in cell-cell adhesion	6/4284	18/18639	0.333333333333333	1.45028011204482	0.216184340148581	0.553632623513967
GO:0004715	non-membrane spanning protein tyrosine kinase activity	13/4284	45/18639	0.288888888888889	1.25690943043884	0.218146924256076	0.556505833747676
GO:0140303	intramembrane lipid transporter activity	13/4284	45/18639	0.288888888888889	1.25690943043884	0.218146924256076	0.556505833747676
GO:0019843	rRNA binding	18/4284	65/18639	0.276923076923077	1.20484809308339	0.22141295459358	0.562669389408638
GO:0120013	lipid transfer activity	18/4284	65/18639	0.276923076923077	1.20484809308339	0.22141295459358	0.562669389408638
GO:0004407	histone deacetylase activity	7/4284	22/18639	0.318181818181818	1.38435828877005	0.225712093068114	0.569224402327966
GO:0008093	cytoskeletal anchor activity	7/4284	22/18639	0.318181818181818	1.38435828877005	0.225712093068114	0.569224402327966
GO:0008649	rRNA methyltransferase activity	7/4284	22/18639	0.318181818181818	1.38435828877005	0.225712093068114	0.569224402327966
GO:0033558	protein lysine deacetylase activity	7/4284	22/18639	0.318181818181818	1.38435828877005	0.225712093068114	0.569224402327966
GO:0008198	ferrous iron binding	8/4284	26/18639	0.307692307692308	1.33872010342599	0.232234681427257	0.575139073613811
GO:0015216	purine nucleotide transmembrane transporter activity	8/4284	26/18639	0.307692307692308	1.33872010342599	0.232234681427257	0.575139073613811
GO:0005114	type II transforming growth factor beta receptor binding	4/4284	11/18639	0.363636363636364	1.58212375859435	0.232835757898038	0.575139073613811
GO:0008432	JUN kinase binding	4/4284	11/18639	0.363636363636364	1.58212375859435	0.232835757898038	0.575139073613811
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/4284	11/18639	0.363636363636364	1.58212375859435	0.232835757898038	0.575139073613811
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	4/4284	11/18639	0.363636363636364	1.58212375859435	0.232835757898038	0.575139073613811
GO:0019215	intermediate filament binding	4/4284	11/18639	0.363636363636364	1.58212375859435	0.232835757898038	0.575139073613811
GO:0034511	U3 snoRNA binding	4/4284	11/18639	0.363636363636364	1.58212375859435	0.232835757898038	0.575139073613811
GO:0047676	arachidonate-CoA ligase activity	4/4284	11/18639	0.363636363636364	1.58212375859435	0.232835757898038	0.575139073613811
GO:0048185	activin binding	4/4284	11/18639	0.363636363636364	1.58212375859435	0.232835757898038	0.575139073613811
GO:1990948	ubiquitin ligase inhibitor activity	4/4284	11/18639	0.363636363636364	1.58212375859435	0.232835757898038	0.575139073613811
GO:0016831	carboxy-lyase activity	10/4284	34/18639	0.294117647058824	1.27965892239249	0.23987951308312	0.591434777136034
GO:0097110	scaffold protein binding	19/4284	70/18639	0.271428571428571	1.18094237695078	0.242105548395324	0.595813654415259
GO:0016859	cis-trans isomerase activity	12/4284	42/18639	0.285714285714286	1.24309723889556	0.243348784762012	0.597762135482195
GO:0015485	cholesterol binding	15/4284	54/18639	0.277777777777778	1.20856676003735	0.244458888920131	0.599376979500469
GO:0050780	dopamine receptor binding	5/4284	15/18639	0.333333333333333	1.45028011204482	0.248985957556261	0.60934825841865
GO:0005516	calmodulin binding	52/4284	207/18639	0.251207729468599	1.09296472212073	0.254620040485546	0.621986962366905
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	6/4284	19/18639	0.315789473684211	1.37394957983193	0.258557624261085	0.626978561395011
GO:0008301	DNA binding, bending	6/4284	19/18639	0.315789473684211	1.37394957983193	0.258557624261085	0.626978561395011
GO:0042800	histone H3K4 methyltransferase activity	6/4284	19/18639	0.315789473684211	1.37394957983193	0.258557624261085	0.626978561395011
GO:0046527	glucosyltransferase activity	6/4284	19/18639	0.315789473684211	1.37394957983193	0.258557624261085	0.626978561395011
GO:0000295	adenine nucleotide transmembrane transporter activity	7/4284	23/18639	0.304347826086957	1.32416879795396	0.264458149052438	0.634316285046064
GO:0008171	O-methyltransferase activity	7/4284	23/18639	0.304347826086957	1.32416879795396	0.264458149052438	0.634316285046064
GO:0031681	G-protein beta-subunit binding	7/4284	23/18639	0.304347826086957	1.32416879795396	0.264458149052438	0.634316285046064
GO:0042171	lysophosphatidic acid acyltransferase activity	7/4284	23/18639	0.304347826086957	1.32416879795396	0.264458149052438	0.634316285046064
GO:0071617	lysophospholipid acyltransferase activity	7/4284	23/18639	0.304347826086957	1.32416879795396	0.264458149052438	0.634316285046064
GO:0140102	catalytic activity, acting on a rRNA	7/4284	23/18639	0.304347826086957	1.32416879795396	0.264458149052438	0.634316285046064
GO:0016830	carbon-carbon lyase activity	14/4284	51/18639	0.274509803921569	1.19434832756632	0.270403710943997	0.647404183164288
GO:0034061	DNA polymerase activity	10/4284	35/18639	0.285714285714286	1.24309723889556	0.271412474830027	0.648480009687355
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	11/4284	39/18639	0.282051282051282	1.22716009480715	0.271832632459578	0.648480009687355
GO:1990782	protein tyrosine kinase binding	30/4284	117/18639	0.256410256410256	1.11560008618832	0.278289959348449	0.662690478736235
GO:0000995	RNA polymerase III general transcription initiation factor activity	4/4284	12/18639	0.333333333333333	1.45028011204482	0.28984148990571	0.678003767906644
GO:0003720	telomerase activity	4/4284	12/18639	0.333333333333333	1.45028011204482	0.28984148990571	0.678003767906644
GO:0003995	acyl-CoA dehydrogenase activity	4/4284	12/18639	0.333333333333333	1.45028011204482	0.28984148990571	0.678003767906644
GO:0005095	GTPase inhibitor activity	4/4284	12/18639	0.333333333333333	1.45028011204482	0.28984148990571	0.678003767906644
GO:0035197	siRNA binding	4/4284	12/18639	0.333333333333333	1.45028011204482	0.28984148990571	0.678003767906644
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	4/4284	12/18639	0.333333333333333	1.45028011204482	0.28984148990571	0.678003767906644
GO:0070679	inositol 1,4,5 trisphosphate binding	4/4284	12/18639	0.333333333333333	1.45028011204482	0.28984148990571	0.678003767906644
GO:0097677	STAT family protein binding	4/4284	12/18639	0.333333333333333	1.45028011204482	0.28984148990571	0.678003767906644
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	4/4284	12/18639	0.333333333333333	1.45028011204482	0.28984148990571	0.678003767906644
GO:1990817	poly(A) RNA polymerase activity	4/4284	12/18639	0.333333333333333	1.45028011204482	0.28984148990571	0.678003767906644
GO:0030159	signaling receptor complex adaptor activity	14/4284	52/18639	0.269230769230769	1.17138009049774	0.29721300303622	0.694021192275053
GO:0008142	oxysterol binding	5/4284	16/18639	0.3125	1.35963760504202	0.298504941245019	0.695810813747192
GO:0003954	NADH dehydrogenase activity	12/4284	44/18639	0.272727272727273	1.18659281894576	0.301089031325222	0.699371714867709
GO:0019205	nucleobase-containing compound kinase activity	12/4284	44/18639	0.272727272727273	1.18659281894576	0.301089031325222	0.699371714867709
GO:0016408	C-acyltransferase activity	6/4284	20/18639	0.3	1.30525210084034	0.302851912944869	0.702234558211921
GO:0050431	transforming growth factor beta binding	7/4284	24/18639	0.291666666666667	1.26899509803922	0.304835601166564	0.703216037388831
GO:0120015	sterol transfer activity	9/4284	32/18639	0.28125	1.22367384453782	0.305056775943872	0.703216037388831
GO:0045499	chemorepellent activity	8/4284	28/18639	0.285714285714286	1.24309723889556	0.305399714122793	0.703216037388831
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	8/4284	28/18639	0.285714285714286	1.24309723889556	0.305399714122793	0.703216037388831
GO:0004519	endonuclease activity	32/4284	127/18639	0.251968503937008	1.09627473036459	0.307482386122037	0.706782429211071
GO:0004713	protein tyrosine kinase activity	35/4284	140/18639	0.25	1.08771008403361	0.314895879394436	0.72256870765725
GO:0019905	syntaxin binding	16/4284	61/18639	0.262295081967213	1.14120402259264	0.318329649488229	0.729184179796565
GO:0015932	nucleobase-containing compound transmembrane transporter activity	15/4284	57/18639	0.263157894736842	1.14495798319328	0.321522179062191	0.735225155575718
GO:1901505	carbohydrate derivative transmembrane transporter activity	14/4284	53/18639	0.264150943396226	1.14927857935627	0.324746844601785	0.741318659056488
GO:0035254	glutamate receptor binding	13/4284	49/18639	0.26530612244898	1.15430457897445	0.327994154865886	0.747442790090247
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	11/4284	41/18639	0.268292682926829	1.16729862676778	0.334492131992388	0.759635647955269
GO:0140828	metal cation:monoatomic cation antiporter activity	11/4284	41/18639	0.268292682926829	1.16729862676778	0.334492131992388	0.759635647955269
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	8/4284	29/18639	0.275862068965517	1.20023181686468	0.343703507748314	0.769637544738984
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	6/4284	21/18639	0.285714285714286	1.24309723889556	0.348341244202485	0.769637544738984
GO:0140312	cargo adaptor activity	6/4284	21/18639	0.285714285714286	1.24309723889556	0.348341244202485	0.769637544738984
GO:1904047	S-adenosyl-L-methionine binding	6/4284	21/18639	0.285714285714286	1.24309723889556	0.348341244202485	0.769637544738984
GO:0002161	aminoacyl-tRNA editing activity	4/4284	13/18639	0.307692307692308	1.33872010342599	0.348384553710156	0.769637544738984
GO:0003964	RNA-directed DNA polymerase activity	4/4284	13/18639	0.307692307692308	1.33872010342599	0.348384553710156	0.769637544738984
GO:0009982	pseudouridine synthase activity	4/4284	13/18639	0.307692307692308	1.33872010342599	0.348384553710156	0.769637544738984
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	4/4284	13/18639	0.307692307692308	1.33872010342599	0.348384553710156	0.769637544738984
GO:0019855	calcium channel inhibitor activity	4/4284	13/18639	0.307692307692308	1.33872010342599	0.348384553710156	0.769637544738984
GO:0039706	co-receptor binding	4/4284	13/18639	0.307692307692308	1.33872010342599	0.348384553710156	0.769637544738984
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	4/4284	13/18639	0.307692307692308	1.33872010342599	0.348384553710156	0.769637544738984
GO:0070123	transforming growth factor beta receptor activity, type III	4/4284	13/18639	0.307692307692308	1.33872010342599	0.348384553710156	0.769637544738984
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	4/4284	13/18639	0.307692307692308	1.33872010342599	0.348384553710156	0.769637544738984
GO:0030169	low-density lipoprotein particle binding	5/4284	17/18639	0.294117647058824	1.27965892239249	0.349359640776533	0.769637544738984
GO:0031489	myosin V binding	5/4284	17/18639	0.294117647058824	1.27965892239249	0.349359640776533	0.769637544738984
GO:0032977	membrane insertase activity	5/4284	17/18639	0.294117647058824	1.27965892239249	0.349359640776533	0.769637544738984
GO:0038191	neuropilin binding	5/4284	17/18639	0.294117647058824	1.27965892239249	0.349359640776533	0.769637544738984
GO:0048038	quinone binding	5/4284	17/18639	0.294117647058824	1.27965892239249	0.349359640776533	0.769637544738984
GO:0016835	carbon-oxygen lyase activity	20/4284	79/18639	0.253164556962025	1.10147856610999	0.351849020988949	0.773834059450777
GO:0050661	NADP binding	14/4284	54/18639	0.259259259259259	1.12799564270152	0.352847629090364	0.774743384603054
GO:0032813	tumor necrosis factor receptor superfamily binding	13/4284	50/18639	0.26	1.13121848739496	0.357340152396333	0.783308545981367
GO:0005109	frizzled binding	10/4284	38/18639	0.263157894736842	1.14495798319328	0.371865597875974	0.813801738161636
GO:0030332	cyclin binding	9/4284	34/18639	0.264705882352941	1.15169303015324	0.377112437831941	0.823922223910049
GO:0008157	protein phosphatase 1 binding	7/4284	26/18639	0.269230769230769	1.17138009049774	0.388327698197139	0.844246095916276
GO:0051139	metal cation:proton antiporter activity	7/4284	26/18639	0.269230769230769	1.17138009049774	0.388327698197139	0.844246095916276
GO:0120014	phospholipid transfer activity	7/4284	26/18639	0.269230769230769	1.17138009049774	0.388327698197139	0.844246095916276
GO:0035401	histone H3Y41 kinase activity	28/4284	115/18639	0.243478260869565	1.05933503836317	0.398959736967709	0.861613081444402
GO:0140801	histone H2AXY142 kinase activity	28/4284	115/18639	0.243478260869565	1.05933503836317	0.398959736967709	0.861613081444402
GO:0003746	translation elongation factor activity	5/4284	18/18639	0.277777777777778	1.20856676003735	0.400580910248822	0.861613081444402
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	5/4284	18/18639	0.277777777777778	1.20856676003735	0.400580910248822	0.861613081444402
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	15/4284	60/18639	0.25	1.08771008403361	0.403572237400301	0.861613081444402
GO:0015386	potassium:proton antiporter activity	4/4284	14/18639	0.285714285714286	1.24309723889556	0.407002422889807	0.861613081444402
GO:0034236	protein kinase A catalytic subunit binding	4/4284	14/18639	0.285714285714286	1.24309723889556	0.407002422889807	0.861613081444402
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	4/4284	14/18639	0.285714285714286	1.24309723889556	0.407002422889807	0.861613081444402
GO:0004857	enzyme inhibitor activity	98/4284	416/18639	0.235576923076923	1.02495757918552	0.408307031121869	0.861613081444402
GO:0016874	ligase activity	40/4284	167/18639	0.239520958083832	1.04211744578071	0.412213007908713	0.861613081444402
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0004090	carbonyl reductase (NADPH) activity	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0005131	growth hormone receptor binding	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0008190	eukaryotic initiation factor 4E binding	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0030957	Tat protein binding	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0032356	oxidized DNA binding	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0033204	ribonuclease P RNA binding	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0042975	peroxisome proliferator activated receptor binding	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0043295	glutathione binding	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0047429	nucleoside triphosphate diphosphatase activity	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0051880	G-quadruplex DNA binding	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0070513	death domain binding	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0097177	mitochondrial ribosome binding	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0140135	mechanosensitive monoatomic cation channel activity	3/4284	10/18639	0.3	1.30525210084034	0.413235881206341	0.861613081444402
GO:0005164	tumor necrosis factor receptor binding	8/4284	31/18639	0.258064516129032	1.12279750609921	0.421663723140602	0.875051362755732
GO:0008327	methyl-CpG binding	8/4284	31/18639	0.258064516129032	1.12279750609921	0.421663723140602	0.875051362755732
GO:0017147	Wnt-protein binding	8/4284	31/18639	0.258064516129032	1.12279750609921	0.421663723140602	0.875051362755732
GO:0160215	deacylase activity	16/4284	65/18639	0.246153846153846	1.07097608274079	0.42422067331159	0.878023106536312
GO:0038187	pattern recognition receptor activity	12/4284	48/18639	0.25	1.08771008403361	0.424422045455619	0.878023106536312
GO:0016836	hydro-lyase activity	15/4284	61/18639	0.245901639344262	1.0698787711806	0.431368733458585	0.891001876909776
GO:0003887	DNA-directed DNA polymerase activity	6/4284	23/18639	0.260869565217391	1.13500182681768	0.440163302992734	0.907751110844828
GO:0016409	palmitoyltransferase activity	9/4284	36/18639	0.25	1.08771008403361	0.450231572647496	0.923532999073855
GO:0045505	dynein intermediate chain binding	9/4284	36/18639	0.25	1.08771008403361	0.450231572647496	0.923532999073855
GO:0008235	metalloexopeptidase activity	16/4284	66/18639	0.242424242424242	1.05474917239623	0.451096954831425	0.923532999073855
GO:0022821	solute:potassium antiporter activity	5/4284	19/18639	0.263157894736842	1.14495798319328	0.451303512387299	0.923532999073855
GO:0046624	sphingolipid transporter activity	5/4284	19/18639	0.263157894736842	1.14495798319328	0.451303512387299	0.923532999073855
GO:0022884	macromolecule transmembrane transporter activity	8/4284	32/18639	0.25	1.08771008403361	0.460532705539512	0.934572877503951
GO:0051015	actin filament binding	49/4284	209/18639	0.23444976076555	1.02005347593583	0.463718645129714	0.934572877503951
GO:0004467	long-chain fatty acid-CoA ligase activity	4/4284	15/18639	0.266666666666667	1.16022408963585	0.464462955738369	0.934572877503951
GO:0005041	low-density lipoprotein particle receptor activity	4/4284	15/18639	0.266666666666667	1.16022408963585	0.464462955738369	0.934572877503951
GO:0016846	carbon-sulfur lyase activity	4/4284	15/18639	0.266666666666667	1.16022408963585	0.464462955738369	0.934572877503951
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	4/4284	15/18639	0.266666666666667	1.16022408963585	0.464462955738369	0.934572877503951
GO:0031005	filamin binding	4/4284	15/18639	0.266666666666667	1.16022408963585	0.464462955738369	0.934572877503951
GO:0033130	acetylcholine receptor binding	4/4284	15/18639	0.266666666666667	1.16022408963585	0.464462955738369	0.934572877503951
GO:0048531	beta-1,3-galactosyltransferase activity	4/4284	15/18639	0.266666666666667	1.16022408963585	0.464462955738369	0.934572877503951
GO:0141050	histone H3K deacetylase activity	4/4284	15/18639	0.266666666666667	1.16022408963585	0.464462955738369	0.934572877503951
GO:0141051	histone H4K deacetylase activity	4/4284	15/18639	0.266666666666667	1.16022408963585	0.464462955738369	0.934572877503951
GO:0140299	molecular sensor activity	17/4284	71/18639	0.23943661971831	1.04175050301811	0.469485427811205	0.939331519382173
GO:0051959	dynein light intermediate chain binding	7/4284	28/18639	0.25	1.08771008403361	0.472075398753274	0.939331519382173
GO:0002020	protease binding	32/4284	136/18639	0.235294117647059	1.02372713791399	0.473059018546989	0.939331519382173
GO:0004812	aminoacyl-tRNA ligase activity	10/4284	41/18639	0.24390243902439	1.06118056978889	0.475222457061417	0.939331519382173
GO:0016875	ligase activity, forming carbon-oxygen bonds	10/4284	41/18639	0.24390243902439	1.06118056978889	0.475222457061417	0.939331519382173
GO:0042169	SH2 domain binding	10/4284	41/18639	0.24390243902439	1.06118056978889	0.475222457061417	0.939331519382173
GO:0048306	calcium-dependent protein binding	19/4284	80/18639	0.2375	1.03332457983193	0.478499211597509	0.939331519382173
GO:0008013	beta-catenin binding	25/4284	106/18639	0.235849056603774	1.02614158871096	0.479117359564456	0.939331519382173
GO:0008172	S-methyltransferase activity	3/4284	11/18639	0.272727272727273	1.18659281894576	0.480885927446954	0.939331519382173
GO:0008526	phosphatidylinositol transfer activity	3/4284	11/18639	0.272727272727273	1.18659281894576	0.480885927446954	0.939331519382173
GO:0015217	ADP transmembrane transporter activity	3/4284	11/18639	0.272727272727273	1.18659281894576	0.480885927446954	0.939331519382173
GO:0019206	nucleoside kinase activity	3/4284	11/18639	0.272727272727273	1.18659281894576	0.480885927446954	0.939331519382173
GO:0032050	clathrin heavy chain binding	3/4284	11/18639	0.272727272727273	1.18659281894576	0.480885927446954	0.939331519382173
GO:0034056	estrogen response element binding	3/4284	11/18639	0.272727272727273	1.18659281894576	0.480885927446954	0.939331519382173
GO:0035252	UDP-xylosyltransferase activity	3/4284	11/18639	0.272727272727273	1.18659281894576	0.480885927446954	0.939331519382173
GO:0042285	xylosyltransferase activity	3/4284	11/18639	0.272727272727273	1.18659281894576	0.480885927446954	0.939331519382173
GO:0045294	alpha-catenin binding	3/4284	11/18639	0.272727272727273	1.18659281894576	0.480885927446954	0.939331519382173
GO:1900750	oligopeptide binding	3/4284	11/18639	0.272727272727273	1.18659281894576	0.480885927446954	0.939331519382173
GO:0004622	lysophospholipase activity	6/4284	24/18639	0.25	1.08771008403361	0.485272536934791	0.939331519382173
GO:0030215	semaphorin receptor binding	6/4284	24/18639	0.25	1.08771008403361	0.485272536934791	0.939331519382173
GO:0042625	ATPase-coupled ion transmembrane transporter activity	6/4284	24/18639	0.25	1.08771008403361	0.485272536934791	0.939331519382173
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	6/4284	24/18639	0.25	1.08771008403361	0.485272536934791	0.939331519382173
GO:0046961	proton-transporting ATPase activity, rotational mechanism	6/4284	24/18639	0.25	1.08771008403361	0.485272536934791	0.939331519382173
GO:0060229	lipase activator activity	6/4284	24/18639	0.25	1.08771008403361	0.485272536934791	0.939331519382173
GO:0070300	phosphatidic acid binding	6/4284	24/18639	0.25	1.08771008403361	0.485272536934791	0.939331519382173
GO:0008238	exopeptidase activity	24/4284	102/18639	0.235294117647059	1.02372713791399	0.486277023608577	0.939331519382173
GO:0019213	deacetylase activity	9/4284	37/18639	0.243243243243243	1.05831251419487	0.486406268218256	0.939331519382173
GO:0017022	myosin binding	18/4284	76/18639	0.236842105263158	1.03046218487395	0.486692917142123	0.939331519382173
GO:0070888	E-box binding	14/4284	59/18639	0.23728813559322	1.03240279162512	0.49629601028194	0.956471495798091
GO:0030276	clathrin binding	11/4284	46/18639	0.239130434782609	1.04041834124954	0.497433998903085	0.957271242075123
GO:0000339	RNA cap binding	5/4284	20/18639	0.25	1.08771008403361	0.500787378868109	0.959540505964365
GO:0016004	phospholipase activator activity	5/4284	20/18639	0.25	1.08771008403361	0.500787378868109	0.959540505964365
GO:0031418	L-ascorbic acid binding	5/4284	20/18639	0.25	1.08771008403361	0.500787378868109	0.959540505964365
GO:0030971	receptor tyrosine kinase binding	19/4284	81/18639	0.234567901234568	1.02056748625376	0.502851888224353	0.962103901747172
GO:0008374	O-acyltransferase activity	13/4284	55/18639	0.236363636363636	1.02838044308633	0.506467864500624	0.967624029724137
GO:0050660	flavin adenine dinucleotide binding	20/4284	86/18639	0.232558139534884	1.01182333398476	0.518073875486162	0.981728612164524
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	4/4284	16/18639	0.25	1.08771008403361	0.519782293902818	0.981728612164524
GO:0004707	MAP kinase activity	4/4284	16/18639	0.25	1.08771008403361	0.519782293902818	0.981728612164524
GO:0005024	transforming growth factor beta receptor activity	4/4284	16/18639	0.25	1.08771008403361	0.519782293902818	0.981728612164524
GO:0005324	long-chain fatty acid transmembrane transporter activity	4/4284	16/18639	0.25	1.08771008403361	0.519782293902818	0.981728612164524
GO:0022858	alanine transmembrane transporter activity	4/4284	16/18639	0.25	1.08771008403361	0.519782293902818	0.981728612164524
GO:0030275	LRR domain binding	4/4284	16/18639	0.25	1.08771008403361	0.519782293902818	0.981728612164524
GO:0140327	flippase activity	4/4284	16/18639	0.25	1.08771008403361	0.519782293902818	0.981728612164524
GO:0042887	amide transmembrane transporter activity	9/4284	38/18639	0.236842105263158	1.03046218487395	0.52195337280724	0.984424879767502
GO:0016829	lyase activity	46/4284	200/18639	0.23	1.00069327731092	0.52559715349013	0.986330022400325
GO:0000030	mannosyltransferase activity	6/4284	25/18639	0.24	1.04420168067227	0.529157762739262	0.986330022400325
GO:0005537	D-mannose binding	6/4284	25/18639	0.24	1.04420168067227	0.529157762739262	0.986330022400325
GO:0120020	cholesterol transfer activity	6/4284	25/18639	0.24	1.04420168067227	0.529157762739262	0.986330022400325
GO:0019212	phosphatase inhibitor activity	13/4284	56/18639	0.232142857142857	1.01001650660264	0.535599733345927	0.986330022400325
GO:0008200	ion channel inhibitor activity	10/4284	43/18639	0.232558139534884	1.01182333398476	0.542295908633492	0.986330022400325
GO:0003774	cytoskeletal motor activity	35/4284	153/18639	0.228758169934641	0.995290272971934	0.544367143393725	0.986330022400325
GO:0000340	RNA 7-methylguanosine cap binding	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0004000	adenosine deaminase activity	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0004526	ribonuclease P activity	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0004859	phospholipase inhibitor activity	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0005025	transforming growth factor beta receptor activity, type I	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0005026	transforming growth factor beta receptor activity, type II	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0005165	neurotrophin receptor binding	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0005247	voltage-gated chloride channel activity	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0008603	cAMP-dependent protein kinase regulator activity	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0015368	calcium:monoatomic cation antiporter activity	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0016273	arginine N-methyltransferase activity	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0016274	protein-arginine N-methyltransferase activity	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0016361	activin receptor activity, type I	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0016362	activin receptor activity, type II	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0017002	activin receptor activity	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0031543	peptidyl-proline dioxygenase activity	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0035251	UDP-glucosyltransferase activity	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0035259	nuclear glucocorticoid receptor binding	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0045295	gamma-catenin binding	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0070008	serine-type exopeptidase activity	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0070410	co-SMAD binding	3/4284	12/18639	0.25	1.08771008403361	0.54456740662737	0.986330022400325
GO:0016757	glycosyltransferase activity	61/4284	267/18639	0.228464419475655	0.994012211626224	0.545536801655397	0.986735963649926
GO:0005080	protein kinase C binding	12/4284	52/18639	0.230769230769231	1.00404007756949	0.547540708727834	0.987914391618066
GO:0005123	death receptor binding	5/4284	21/18639	0.238095238095238	1.0359143657463	0.548426795951117	0.987914391618066
GO:0070182	DNA polymerase binding	5/4284	21/18639	0.238095238095238	1.0359143657463	0.548426795951117	0.987914391618066
GO:0043178	alcohol binding	21/4284	92/18639	0.228260869565217	0.993126598465473	0.555018969522436	0.998430863651773
GO:0005112	Notch binding	6/4284	26/18639	0.230769230769231	1.00404007756949	0.571406782101898	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/4284	17/18639	0.235294117647059	1.02372713791399	0.572220033326292	1
GO:0004549	tRNA-specific ribonuclease activity	4/4284	17/18639	0.235294117647059	1.02372713791399	0.572220033326292	1
GO:0016018	cyclosporin A binding	4/4284	17/18639	0.235294117647059	1.02372713791399	0.572220033326292	1
GO:0017110	nucleoside diphosphate phosphatase activity	4/4284	17/18639	0.235294117647059	1.02372713791399	0.572220033326292	1
GO:0036041	long-chain fatty acid binding	4/4284	17/18639	0.235294117647059	1.02372713791399	0.572220033326292	1
GO:0070402	NADPH binding	4/4284	17/18639	0.235294117647059	1.02372713791399	0.572220033326292	1
GO:0016229	steroid dehydrogenase activity	8/4284	35/18639	0.228571428571429	0.994477791116447	0.572638417879799	1
GO:0016248	channel inhibitor activity	10/4284	44/18639	0.227272727272727	0.988827349121467	0.574635602409718	1
GO:0005246	calcium channel regulator activity	12/4284	53/18639	0.226415094339623	0.985095925162518	0.576957803931057	1
GO:0005544	calcium-dependent phospholipid binding	12/4284	53/18639	0.226415094339623	0.985095925162518	0.576957803931057	1
GO:0071949	FAD binding	9/4284	40/18639	0.225	0.978939075630252	0.59023151005179	1
GO:0016411	acylglycerol O-acyltransferase activity	7/4284	31/18639	0.225806451612903	0.982447817836812	0.590771514695177	1
GO:0016878	acid-thiol ligase activity	7/4284	31/18639	0.225806451612903	0.982447817836812	0.590771514695177	1
GO:0008970	phospholipase A1 activity	5/4284	22/18639	0.227272727272727	0.988827349121467	0.593750213619717	1
GO:0005319	lipid transporter activity	40/4284	178/18639	0.224719101123595	0.977716929468417	0.593929213946268	1
GO:0009055	electron transfer activity	26/4284	116/18639	0.224137931034483	0.97518835120255	0.594201226921313	1
GO:0003779	actin binding	100/4284	443/18639	0.225733634311512	0.982131001384753	0.600983837816684	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	3/4284	13/18639	0.230769230769231	1.00404007756949	0.603422262502533	1
GO:0005035	death receptor activity	3/4284	13/18639	0.230769230769231	1.00404007756949	0.603422262502533	1
GO:0005172	vascular endothelial growth factor receptor binding	3/4284	13/18639	0.230769230769231	1.00404007756949	0.603422262502533	1
GO:0043560	insulin receptor substrate binding	3/4284	13/18639	0.230769230769231	1.00404007756949	0.603422262502533	1
GO:0070700	BMP receptor binding	3/4284	13/18639	0.230769230769231	1.00404007756949	0.603422262502533	1
GO:0046915	transition metal ion transmembrane transporter activity	10/4284	45/18639	0.222222222222222	0.966853408029879	0.605946657149549	1
GO:0141110	transporter inhibitor activity	10/4284	45/18639	0.222222222222222	0.966853408029879	0.605946657149549	1
GO:0070851	growth factor receptor binding	31/4284	139/18639	0.223021582733813	0.970331297986821	0.608819182296307	1
GO:0004364	glutathione transferase activity	6/4284	27/18639	0.222222222222222	0.966853408029879	0.611692583389397	1
GO:0005044	scavenger receptor activity	6/4284	27/18639	0.222222222222222	0.966853408029879	0.611692583389397	1
GO:0008320	protein transmembrane transporter activity	6/4284	27/18639	0.222222222222222	0.966853408029879	0.611692583389397	1
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	6/4284	27/18639	0.222222222222222	0.966853408029879	0.611692583389397	1
GO:0005496	steroid binding	24/4284	108/18639	0.222222222222222	0.966853408029879	0.611959923283847	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	15/4284	68/18639	0.220588235294118	0.959744191794365	0.618744877529988	1
GO:0001786	phosphatidylserine binding	13/4284	59/18639	0.220338983050847	0.958659735080473	0.619061821170196	1
GO:0016209	antioxidant activity	19/4284	86/18639	0.22093023255814	0.961232167285519	0.61951297420105	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	4/4284	18/18639	0.222222222222222	0.966853408029879	0.621259782776997	1
GO:0016854	racemase and epimerase activity	4/4284	18/18639	0.222222222222222	0.966853408029879	0.621259782776997	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	4/4284	18/18639	0.222222222222222	0.966853408029879	0.621259782776997	1
GO:0030228	lipoprotein particle receptor activity	4/4284	18/18639	0.222222222222222	0.966853408029879	0.621259782776997	1
GO:0034185	apolipoprotein binding	4/4284	18/18639	0.222222222222222	0.966853408029879	0.621259782776997	1
GO:0035615	clathrin adaptor activity	4/4284	18/18639	0.222222222222222	0.966853408029879	0.621259782776997	1
GO:0017080	sodium channel regulator activity	9/4284	41/18639	0.219512195121951	0.955062512810002	0.622577806205333	1
GO:0008378	galactosyltransferase activity	7/4284	32/18639	0.21875	0.951746323529412	0.627238381258764	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/4284	32/18639	0.21875	0.951746323529412	0.627238381258764	1
GO:0043425	bHLH transcription factor binding	7/4284	32/18639	0.21875	0.951746323529412	0.627238381258764	1
GO:0071813	lipoprotein particle binding	7/4284	32/18639	0.21875	0.951746323529412	0.627238381258764	1
GO:0071814	protein-lipid complex binding	7/4284	32/18639	0.21875	0.951746323529412	0.627238381258764	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	20/4284	91/18639	0.21978021978022	0.956228645304276	0.630610888932472	1
GO:0098632	cell-cell adhesion mediator activity	12/4284	55/18639	0.218181818181818	0.949274255156608	0.633196949383839	1
GO:0004602	glutathione peroxidase activity	5/4284	23/18639	0.217391304347826	0.945834855681403	0.636413244349436	1
GO:0017134	fibroblast growth factor binding	5/4284	23/18639	0.217391304347826	0.945834855681403	0.636413244349436	1
GO:0140103	catalytic activity, acting on a glycoprotein	5/4284	23/18639	0.217391304347826	0.945834855681403	0.636413244349436	1
GO:0016866	intramolecular transferase activity	6/4284	28/18639	0.214285714285714	0.932322929171669	0.649769997381067	1
GO:0048029	monosaccharide binding	16/4284	74/18639	0.216216216216216	0.940722234839882	0.654070468737988	1
GO:0038024	cargo receptor activity	14/4284	65/18639	0.215384615384615	0.93710407239819	0.656377178606082	1
GO:0004705	JUN kinase activity	3/4284	14/18639	0.214285714285714	0.932322929171669	0.65699130966964	1
GO:0008191	metalloendopeptidase inhibitor activity	3/4284	14/18639	0.214285714285714	0.932322929171669	0.65699130966964	1
GO:0008474	palmitoyl-(protein) hydrolase activity	3/4284	14/18639	0.214285714285714	0.932322929171669	0.65699130966964	1
GO:0032036	myosin heavy chain binding	3/4284	14/18639	0.214285714285714	0.932322929171669	0.65699130966964	1
GO:0042813	Wnt receptor activity	3/4284	14/18639	0.214285714285714	0.932322929171669	0.65699130966964	1
GO:0098599	palmitoyl hydrolase activity	3/4284	14/18639	0.214285714285714	0.932322929171669	0.65699130966964	1
GO:0098821	BMP receptor activity	3/4284	14/18639	0.214285714285714	0.932322929171669	0.65699130966964	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	7/4284	33/18639	0.212121212121212	0.922905525846702	0.661804045817176	1
GO:0019239	deaminase activity	7/4284	33/18639	0.212121212121212	0.922905525846702	0.661804045817176	1
GO:0043495	protein-membrane adaptor activity	10/4284	47/18639	0.212765957446809	0.925710709815841	0.664949122188364	1
GO:0015245	fatty acid transmembrane transporter activity	4/4284	19/18639	0.210526315789474	0.915966386554622	0.666581454880917	1
GO:0070003	threonine-type peptidase activity	4/4284	19/18639	0.210526315789474	0.915966386554622	0.666581454880917	1
GO:0000146	microfilament motor activity	8/4284	38/18639	0.210526315789474	0.915966386554622	0.672806328630345	1
GO:0005540	hyaluronic acid binding	5/4284	24/18639	0.208333333333333	0.906425070028011	0.67618711472171	1
GO:0070840	dynein complex binding	5/4284	24/18639	0.208333333333333	0.906425070028011	0.67618711472171	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	9/4284	43/18639	0.209302325581395	0.910641000586281	0.682971685349914	1
GO:0016417	S-acyltransferase activity	6/4284	29/18639	0.206896551724138	0.900173862648508	0.685469735714388	1
GO:0035250	UDP-galactosyltransferase activity	6/4284	29/18639	0.206896551724138	0.900173862648508	0.685469735714388	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	10/4284	48/18639	0.208333333333333	0.906425070028011	0.69243867898247	1
GO:0098631	cell adhesion mediator activity	16/4284	76/18639	0.210526315789474	0.915966386554622	0.698296395646101	1
GO:0004864	protein phosphatase inhibitor activity	11/4284	53/18639	0.207547169811321	0.903004598065641	0.70131029375734	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	26/4284	122/18639	0.213114754098361	0.927228268356523	0.703552067729599	1
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/4284	15/18639	0.2	0.870168067226891	0.705123398152459	1
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/4284	15/18639	0.2	0.870168067226891	0.705123398152459	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	3/4284	15/18639	0.2	0.870168067226891	0.705123398152459	1
GO:0005523	tropomyosin binding	3/4284	15/18639	0.2	0.870168067226891	0.705123398152459	1
GO:0015929	hexosaminidase activity	3/4284	15/18639	0.2	0.870168067226891	0.705123398152459	1
GO:0017081	chloride channel regulator activity	3/4284	15/18639	0.2	0.870168067226891	0.705123398152459	1
GO:0045504	dynein heavy chain binding	3/4284	15/18639	0.2	0.870168067226891	0.705123398152459	1
GO:0001094	TFIID-class transcription factor complex binding	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0004382	GDP phosphatase activity	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0005031	tumor necrosis factor receptor activity	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0005522	profilin binding	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0015187	glycine transmembrane transporter activity	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0015643	toxic substance binding	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0016868	intramolecular phosphotransferase activity	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0019531	oxalate transmembrane transporter activity	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0031419	cobalamin binding	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0035256	G protein-coupled glutamate receptor binding	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0035374	chondroitin sulfate binding	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0051864	histone H3K36 demethylase activity	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0140940	histone H2A methyltransferase activity	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0141109	transporter activator activity	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:1990259	histone H2AQ104 methyltransferase activity	2/4284	10/18639	0.2	0.870168067226891	0.707549919369907	1
GO:0042288	MHC class I protein binding	4/4284	20/18639	0.2	0.870168067226891	0.708029973884118	1
GO:0016790	thiolester hydrolase activity	9/4284	44/18639	0.204545454545455	0.88994461420932	0.710829535248821	1
GO:0003707	nuclear steroid receptor activity	5/4284	25/18639	0.2	0.870168067226891	0.712944452717323	1
GO:0015645	fatty acid ligase activity	5/4284	25/18639	0.2	0.870168067226891	0.712944452717323	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	5/4284	25/18639	0.2	0.870168067226891	0.712944452717323	1
GO:0019707	protein-cysteine S-acyltransferase activity	5/4284	25/18639	0.2	0.870168067226891	0.712944452717323	1
GO:0047617	fatty acyl-CoA hydrolase activity	5/4284	25/18639	0.2	0.870168067226891	0.712944452717323	1
GO:0120515	fatty acid-CoA ligase activity	5/4284	25/18639	0.2	0.870168067226891	0.712944452717323	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	6/4284	30/18639	0.2	0.870168067226891	0.718690698556948	1
GO:0072341	modified amino acid binding	19/4284	91/18639	0.208791208791209	0.908417213039062	0.72192773934392	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/4284	59/18639	0.203389830508475	0.884916678535821	0.732798612169482	1
GO:0033218	amide binding	53/4284	247/18639	0.214574898785425	0.933581124757595	0.739668037648047	1
GO:0052689	carboxylic ester hydrolase activity	19/4284	92/18639	0.206521739130435	0.898543112897333	0.740229969554545	1
GO:0001846	opsonin binding	4/4284	21/18639	0.19047619047619	0.828731492597039	0.74558366280953	1
GO:0005248	voltage-gated sodium channel activity	4/4284	21/18639	0.19047619047619	0.828731492597039	0.74558366280953	1
GO:0008373	sialyltransferase activity	4/4284	21/18639	0.19047619047619	0.828731492597039	0.74558366280953	1
GO:0009931	calcium-dependent protein serine/threonine kinase activity	4/4284	21/18639	0.19047619047619	0.828731492597039	0.74558366280953	1
GO:0009975	cyclase activity	4/4284	21/18639	0.19047619047619	0.828731492597039	0.74558366280953	1
GO:0019200	carbohydrate kinase activity	4/4284	21/18639	0.19047619047619	0.828731492597039	0.74558366280953	1
GO:0051428	peptide hormone receptor binding	4/4284	21/18639	0.19047619047619	0.828731492597039	0.74558366280953	1
GO:0003735	structural constituent of ribosome	37/4284	175/18639	0.211428571428571	0.919891956782713	0.746317513242671	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	5/4284	26/18639	0.192307692307692	0.836700064641241	0.746643898101947	1
GO:0016289	acyl-CoA hydrolase activity	5/4284	26/18639	0.192307692307692	0.836700064641241	0.746643898101947	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	3/4284	16/18639	0.1875	0.81578256302521	0.747894422210068	1
GO:0004708	MAP kinase kinase activity	3/4284	16/18639	0.1875	0.81578256302521	0.747894422210068	1
GO:0005149	interleukin-1 receptor binding	3/4284	16/18639	0.1875	0.81578256302521	0.747894422210068	1
GO:0015385	sodium:proton antiporter activity	3/4284	16/18639	0.1875	0.81578256302521	0.747894422210068	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/4284	16/18639	0.1875	0.81578256302521	0.747894422210068	1
GO:0055102	lipase inhibitor activity	3/4284	16/18639	0.1875	0.81578256302521	0.747894422210068	1
GO:0140328	floppase activity	3/4284	16/18639	0.1875	0.81578256302521	0.747894422210068	1
GO:1902936	phosphatidylinositol bisphosphate binding	23/4284	111/18639	0.207207207207207	0.901525475054887	0.748716417232097	1
GO:0004033	aldo-keto reductase (NADPH) activity	7/4284	36/18639	0.194444444444444	0.845996732026144	0.753043198667061	1
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0002162	dystroglycan binding	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0004016	adenylate cyclase activity	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0008271	secondary active sulfate transmembrane transporter activity	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0010854	adenylate cyclase regulator activity	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0043522	leucine zipper domain binding	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0050786	RAGE receptor binding	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0097493	structural molecule activity conferring elasticity	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/4284	11/18639	0.181818181818182	0.791061879297173	0.757919695352785	1
GO:0004180	carboxypeptidase activity	9/4284	46/18639	0.195652173913043	0.851251370113263	0.761608382692576	1
GO:0016597	amino acid binding	10/4284	51/18639	0.196078431372549	0.853105948261658	0.766156342058752	1
GO:0030170	pyridoxal phosphate binding	11/4284	56/18639	0.196428571428571	0.854629351740696	0.770751929809328	1
GO:0005385	zinc ion transmembrane transporter activity	5/4284	27/18639	0.185185185185185	0.805711173358232	0.777314651445709	1
GO:0016405	CoA-ligase activity	5/4284	27/18639	0.185185185185185	0.805711173358232	0.777314651445709	1
GO:0042805	actinin binding	7/4284	37/18639	0.189189189189189	0.823131955484897	0.779175455645887	1
GO:0061133	endopeptidase activator activity	4/4284	22/18639	0.181818181818182	0.791061879297173	0.779324429296156	1
GO:0019894	kinesin binding	8/4284	42/18639	0.19047619047619	0.828731492597039	0.781583516583206	1
GO:0046982	protein heterodimerization activity	79/4284	369/18639	0.214092140921409	0.931480722370249	0.783663982905933	1
GO:0022853	active monoatomic ion transmembrane transporter activity	24/4284	118/18639	0.203389830508475	0.884916678535821	0.784512248476794	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	27/4284	132/18639	0.204545454545455	0.88994461420932	0.785287377414677	1
GO:0004550	nucleoside diphosphate kinase activity	3/4284	17/18639	0.176470588235294	0.767795353435492	0.785538934113734	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/4284	17/18639	0.176470588235294	0.767795353435492	0.785538934113734	1
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/4284	17/18639	0.176470588235294	0.767795353435492	0.785538934113734	1
GO:0008429	phosphatidylethanolamine binding	3/4284	17/18639	0.176470588235294	0.767795353435492	0.785538934113734	1
GO:0019198	transmembrane receptor protein phosphatase activity	3/4284	17/18639	0.176470588235294	0.767795353435492	0.785538934113734	1
GO:0004601	peroxidase activity	11/4284	57/18639	0.192982456140351	0.839635854341737	0.791180466625667	1
GO:0070279	vitamin B6 binding	11/4284	57/18639	0.192982456140351	0.839635854341737	0.791180466625667	1
GO:0001618	virus receptor activity	16/4284	81/18639	0.197530864197531	0.859425251582114	0.793121655094524	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	17/4284	86/18639	0.197674418604651	0.860049833887043	0.797359146972851	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	13/4284	67/18639	0.194029850746269	0.844192901041013	0.798361155489409	1
GO:0005078	MAP-kinase scaffold activity	2/4284	12/18639	0.166666666666667	0.725140056022409	0.800590153097869	1
GO:0010853	cyclase activator activity	2/4284	12/18639	0.166666666666667	0.725140056022409	0.800590153097869	1
GO:0015269	calcium-activated potassium channel activity	2/4284	12/18639	0.166666666666667	0.725140056022409	0.800590153097869	1
GO:0016423	tRNA (guanine) methyltransferase activity	2/4284	12/18639	0.166666666666667	0.725140056022409	0.800590153097869	1
GO:0016840	carbon-nitrogen lyase activity	2/4284	12/18639	0.166666666666667	0.725140056022409	0.800590153097869	1
GO:0036009	protein-glutamine N-methyltransferase activity	2/4284	12/18639	0.166666666666667	0.725140056022409	0.800590153097869	1
GO:0042301	phosphate ion binding	2/4284	12/18639	0.166666666666667	0.725140056022409	0.800590153097869	1
GO:0097371	MDM2/MDM4 family protein binding	2/4284	12/18639	0.166666666666667	0.725140056022409	0.800590153097869	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	2/4284	12/18639	0.166666666666667	0.725140056022409	0.800590153097869	1
GO:0140900	chloride:bicarbonate antiporter activity	2/4284	12/18639	0.166666666666667	0.725140056022409	0.800590153097869	1
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/4284	12/18639	0.166666666666667	0.725140056022409	0.800590153097869	1
GO:0051393	alpha-actinin binding	5/4284	28/18639	0.178571428571429	0.776935774309724	0.805041750155413	1
GO:0140272	exogenous protein binding	16/4284	82/18639	0.195121951219512	0.848944455831113	0.809276674664382	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/4284	23/18639	0.173913043478261	0.756667884545122	0.809410994548097	1
GO:0008525	phosphatidylcholine transporter activity	3/4284	18/18639	0.166666666666667	0.725140056022409	0.818394764381081	1
GO:0050811	GABA receptor binding	3/4284	18/18639	0.166666666666667	0.725140056022409	0.818394764381081	1
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	6/4284	34/18639	0.176470588235294	0.767795353435492	0.82665901380768	1
GO:0051427	hormone receptor binding	6/4284	34/18639	0.176470588235294	0.767795353435492	0.82665901380768	1
GO:0004629	phospholipase C activity	5/4284	29/18639	0.172413793103448	0.750144885540423	0.829952586497294	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/4284	24/18639	0.166666666666667	0.725140056022409	0.836055770513374	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/4284	24/18639	0.166666666666667	0.725140056022409	0.836055770513374	1
GO:0005315	phosphate transmembrane transporter activity	4/4284	24/18639	0.166666666666667	0.725140056022409	0.836055770513374	1
GO:0015295	solute:proton symporter activity	4/4284	24/18639	0.166666666666667	0.725140056022409	0.836055770513374	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	4/4284	24/18639	0.166666666666667	0.725140056022409	0.836055770513374	1
GO:0030552	cAMP binding	4/4284	24/18639	0.166666666666667	0.725140056022409	0.836055770513374	1
GO:0050699	WW domain binding	4/4284	24/18639	0.166666666666667	0.725140056022409	0.836055770513374	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/4284	24/18639	0.166666666666667	0.725140056022409	0.836055770513374	1
GO:0005542	folic acid binding	2/4284	13/18639	0.153846153846154	0.669360051712993	0.836438860478839	1
GO:0008035	high-density lipoprotein particle binding	2/4284	13/18639	0.153846153846154	0.669360051712993	0.836438860478839	1
GO:0008417	fucosyltransferase activity	2/4284	13/18639	0.153846153846154	0.669360051712993	0.836438860478839	1
GO:0019104	DNA N-glycosylase activity	2/4284	13/18639	0.153846153846154	0.669360051712993	0.836438860478839	1
GO:0031432	titin binding	2/4284	13/18639	0.153846153846154	0.669360051712993	0.836438860478839	1
GO:0031994	insulin-like growth factor I binding	2/4284	13/18639	0.153846153846154	0.669360051712993	0.836438860478839	1
GO:0035325	Toll-like receptor binding	2/4284	13/18639	0.153846153846154	0.669360051712993	0.836438860478839	1
GO:0045159	myosin II binding	2/4284	13/18639	0.153846153846154	0.669360051712993	0.836438860478839	1
GO:0061459	L-arginine transmembrane transporter activity	2/4284	13/18639	0.153846153846154	0.669360051712993	0.836438860478839	1
GO:0071837	HMG box domain binding	2/4284	13/18639	0.153846153846154	0.669360051712993	0.836438860478839	1
GO:0089720	caspase binding	2/4284	13/18639	0.153846153846154	0.669360051712993	0.836438860478839	1
GO:0140333	glycerophospholipid flippase activity	2/4284	13/18639	0.153846153846154	0.669360051712993	0.836438860478839	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	3/4284	19/18639	0.157894736842105	0.686974789915966	0.846859759912362	1
GO:0005520	insulin-like growth factor binding	3/4284	19/18639	0.157894736842105	0.686974789915966	0.846859759912362	1
GO:0008381	mechanosensitive monoatomic ion channel activity	3/4284	19/18639	0.157894736842105	0.686974789915966	0.846859759912362	1
GO:0030506	ankyrin binding	3/4284	19/18639	0.157894736842105	0.686974789915966	0.846859759912362	1
GO:0042577	lipid phosphatase activity	3/4284	19/18639	0.157894736842105	0.686974789915966	0.846859759912362	1
GO:0031210	phosphatidylcholine binding	5/4284	30/18639	0.166666666666667	0.725140056022409	0.852204964085363	1
GO:0033612	receptor serine/threonine kinase binding	5/4284	30/18639	0.166666666666667	0.725140056022409	0.852204964085363	1
GO:0015399	primary active transmembrane transporter activity	33/4284	166/18639	0.198795180722892	0.864926090918295	0.85308461296667	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/4284	25/18639	0.16	0.696134453781513	0.85950554533167	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	4/4284	25/18639	0.16	0.696134453781513	0.85950554533167	1
GO:0001530	lipopolysaccharide binding	7/4284	41/18639	0.170731707317073	0.742826398852224	0.863255548623712	1
GO:0015926	glucosidase activity	2/4284	14/18639	0.142857142857143	0.621548619447779	0.866346785613705	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/4284	14/18639	0.142857142857143	0.621548619447779	0.866346785613705	1
GO:0042043	neurexin family protein binding	2/4284	14/18639	0.142857142857143	0.621548619447779	0.866346785613705	1
GO:0044548	S100 protein binding	2/4284	14/18639	0.142857142857143	0.621548619447779	0.866346785613705	1
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/4284	14/18639	0.142857142857143	0.621548619447779	0.866346785613705	1
GO:1901612	cardiolipin binding	2/4284	14/18639	0.142857142857143	0.621548619447779	0.866346785613705	1
GO:0004190	aspartic-type endopeptidase activity	6/4284	36/18639	0.166666666666667	0.725140056022409	0.866680032836552	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	25/4284	130/18639	0.192307692307692	0.836700064641241	0.871037581361256	1
GO:0001972	retinoic acid binding	3/4284	20/18639	0.15	0.652626050420168	0.871359133917347	1
GO:0047499	calcium-independent phospholipase A2 activity	5/4284	31/18639	0.161290322580645	0.701748441312009	0.871976822047208	1
GO:0072349	modified amino acid transmembrane transporter activity	5/4284	31/18639	0.161290322580645	0.701748441312009	0.871976822047208	1
GO:0015297	antiporter activity	26/4284	135/18639	0.192592592592593	0.837939620292561	0.8731427567044	1
GO:0140359	ABC-type transporter activity	8/4284	47/18639	0.170212765957447	0.740568567852673	0.876875410202415	1
GO:0031492	nucleosomal DNA binding	7/4284	42/18639	0.166666666666667	0.725140056022409	0.879589955031813	1
GO:0004435	phosphatidylinositol phospholipase C activity	4/4284	26/18639	0.153846153846154	0.669360051712993	0.880025844827983	1
GO:0019838	growth factor binding	26/4284	136/18639	0.191176470588235	0.831778299555116	0.882237648976952	1
GO:0030551	cyclic nucleotide binding	6/4284	37/18639	0.162162162162162	0.705541676129911	0.88361640261539	1
GO:0070001	aspartic-type peptidase activity	6/4284	37/18639	0.162162162162162	0.705541676129911	0.88361640261539	1
GO:0005507	copper ion binding	11/4284	63/18639	0.174603174603175	0.759670534880619	0.886539853768545	1
GO:0042626	ATPase-coupled transmembrane transporter activity	18/4284	98/18639	0.183673469387755	0.799133939290002	0.889059001204842	1
GO:0047498	calcium-dependent phospholipase A2 activity	5/4284	32/18639	0.15625	0.679818802521008	0.889457633834239	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/4284	15/18639	0.133333333333333	0.580112044817927	0.891150383684666	1
GO:0008242	omega peptidase activity	2/4284	15/18639	0.133333333333333	0.580112044817927	0.891150383684666	1
GO:0015116	sulfate transmembrane transporter activity	2/4284	15/18639	0.133333333333333	0.580112044817927	0.891150383684666	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/4284	15/18639	0.133333333333333	0.580112044817927	0.891150383684666	1
GO:0030553	cGMP binding	2/4284	15/18639	0.133333333333333	0.580112044817927	0.891150383684666	1
GO:0051371	muscle alpha-actinin binding	2/4284	15/18639	0.133333333333333	0.580112044817927	0.891150383684666	1
GO:0015174	basic amino acid transmembrane transporter activity	3/4284	21/18639	0.142857142857143	0.621548619447779	0.892321712435316	1
GO:0061891	calcium ion sensor activity	3/4284	21/18639	0.142857142857143	0.621548619447779	0.892321712435316	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	4/4284	27/18639	0.148148148148148	0.644568938686586	0.897888661068378	1
GO:0023026	MHC class II protein complex binding	4/4284	27/18639	0.148148148148148	0.644568938686586	0.897888661068378	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	35/4284	181/18639	0.193370165745856	0.841322716932077	0.898183111027147	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	9/4284	54/18639	0.166666666666667	0.725140056022409	0.901379712744615	1
GO:0016782	transferase activity, transferring sulphur-containing groups	12/4284	70/18639	0.171428571428571	0.745858343337335	0.907973157024066	1
GO:0042277	peptide binding	49/4284	249/18639	0.196787148594378	0.856189463737302	0.909074790786099	1
GO:0016758	hexosyltransferase activity	38/4284	197/18639	0.192893401015228	0.839248389711214	0.909406382989845	1
GO:0005506	iron ion binding	29/4284	154/18639	0.188311688311688	0.819314089272072	0.91005818101917	1
GO:0015377	chloride:monoatomic cation symporter activity	3/4284	22/18639	0.136363636363636	0.59329640947288	0.910163388720446	1
GO:0016881	acid-amino acid ligase activity	3/4284	22/18639	0.136363636363636	0.59329640947288	0.910163388720446	1
GO:0031683	G-protein beta/gamma-subunit complex binding	3/4284	22/18639	0.136363636363636	0.59329640947288	0.910163388720446	1
GO:0140784	metal ion sensor activity	3/4284	22/18639	0.136363636363636	0.59329640947288	0.910163388720446	1
GO:0015562	efflux transmembrane transporter activity	2/4284	16/18639	0.125	0.543855042016807	0.91161552103818	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	24/4284	130/18639	0.184615384615385	0.803232062055592	0.911728986910454	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	5/4284	34/18639	0.147058823529412	0.639829461196243	0.918321125456414	1
GO:0015026	coreceptor activity	10/4284	61/18639	0.163934426229508	0.713252514120402	0.920555926747999	1
GO:0015078	proton transmembrane transporter activity	35/4284	185/18639	0.189189189189189	0.823131955484897	0.92306245594926	1
GO:0050997	quaternary ammonium group binding	6/4284	40/18639	0.15	0.652626050420168	0.92387514042764	1
GO:0005212	structural constituent of eye lens	3/4284	23/18639	0.130434782608696	0.567500913408842	0.925276247846299	1
GO:0005283	amino acid:sodium symporter activity	3/4284	23/18639	0.130434782608696	0.567500913408842	0.925276247846299	1
GO:0043274	phospholipase binding	3/4284	23/18639	0.130434782608696	0.567500913408842	0.925276247846299	1
GO:0005021	vascular endothelial growth factor receptor activity	8/4284	51/18639	0.156862745098039	0.682484758609326	0.925759021787761	1
GO:0000182	rDNA binding	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0004935	adrenergic receptor activity	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0004955	prostaglandin receptor activity	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0005345	purine nucleobase transmembrane transporter activity	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0008519	ammonium channel activity	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0015203	polyamine transmembrane transporter activity	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0019911	structural constituent of myelin sheath	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0032052	bile acid binding	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0042166	acetylcholine binding	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0043121	neurotrophin binding	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0050308	sugar-phosphatase activity	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0070097	delta-catenin binding	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0070739	protein-glutamic acid ligase activity	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0070740	tubulin-glutamic acid ligase activity	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:1990763	arrestin family protein binding	1/4284	10/18639	0.1	0.435084033613445	0.926634336083669	1
GO:0043236	laminin binding	4/4284	29/18639	0.137931034482759	0.600115908432338	0.926708835776259	1
GO:0099604	ligand-gated calcium channel activity	4/4284	29/18639	0.137931034482759	0.600115908432338	0.926708835776259	1
GO:0008569	minus-end-directed microtubule motor activity	2/4284	17/18639	0.117647058823529	0.511863568956995	0.928425732628106	1
GO:0015278	intracellularly gated calcium channel activity	2/4284	17/18639	0.117647058823529	0.511863568956995	0.928425732628106	1
GO:0045125	bioactive lipid receptor activity	2/4284	17/18639	0.117647058823529	0.511863568956995	0.928425732628106	1
GO:0004623	phospholipase A2 activity	5/4284	35/18639	0.142857142857143	0.621548619447779	0.930084552953322	1
GO:0001540	amyloid-beta binding	14/4284	83/18639	0.168674698795181	0.733876683203402	0.931934762951328	1
GO:0019199	transmembrane receptor protein kinase activity	13/4284	78/18639	0.166666666666667	0.725140056022409	0.932891164133306	1
GO:0004521	RNA endonuclease activity	12/4284	73/18639	0.164383561643836	0.715206630597444	0.934133381386703	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	6/4284	41/18639	0.146341463414634	0.636708341873335	0.93426707045117	1
GO:0016247	channel regulator activity	31/4284	168/18639	0.18452380952381	0.802833633453381	0.935449564567737	1
GO:0001968	fibronectin binding	4/4284	30/18639	0.133333333333333	0.580112044817927	0.93817096988255	1
GO:0016769	transferase activity, transferring nitrogenous groups	4/4284	30/18639	0.133333333333333	0.580112044817927	0.93817096988255	1
GO:0098918	structural constituent of synapse	4/4284	30/18639	0.133333333333333	0.580112044817927	0.93817096988255	1
GO:0005504	fatty acid binding	7/4284	47/18639	0.148936170212766	0.647997496871089	0.938714401306815	1
GO:0033293	monocarboxylic acid binding	13/4284	79/18639	0.164556962025316	0.715961067971492	0.939964888792046	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	5/4284	36/18639	0.138888888888889	0.604283380018674	0.940311088456027	1
GO:0004970	glutamate-gated receptor activity	2/4284	18/18639	0.111111111111111	0.483426704014939	0.942179603658985	1
GO:0015172	acidic amino acid transmembrane transporter activity	2/4284	18/18639	0.111111111111111	0.483426704014939	0.942179603658985	1
GO:0015280	ligand-gated sodium channel activity	2/4284	18/18639	0.111111111111111	0.483426704014939	0.942179603658985	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/4284	18/18639	0.111111111111111	0.483426704014939	0.942179603658985	1
GO:1901611	phosphatidylglycerol binding	2/4284	18/18639	0.111111111111111	0.483426704014939	0.942179603658985	1
GO:0008194	UDP-glycosyltransferase activity	26/4284	145/18639	0.179310344827586	0.78015068096204	0.942921152500465	1
GO:0005003	ephrin receptor activity	8/4284	53/18639	0.150943396226415	0.656730616775012	0.943153358745416	1
GO:0005005	transmembrane-ephrin receptor activity	8/4284	53/18639	0.150943396226415	0.656730616775012	0.943153358745416	1
GO:0038064	collagen receptor activity	8/4284	53/18639	0.150943396226415	0.656730616775012	0.943153358745416	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0004954	prostanoid receptor activity	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0005536	D-glucose binding	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0008046	axon guidance receptor activity	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0008503	benzodiazepine receptor activity	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0015173	aromatic amino acid transmembrane transporter activity	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0015205	nucleobase transmembrane transporter activity	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0016594	glycine binding	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0019203	carbohydrate phosphatase activity	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0032794	GTPase activating protein binding	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0042608	T cell receptor binding	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0048407	platelet-derived growth factor binding	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0070697	activin receptor binding	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/4284	11/18639	0.0909090909090909	0.395530939648587	0.943505800156757	1
GO:0099106	ion channel regulator activity	29/4284	160/18639	0.18125	0.78858981092437	0.944012305458247	1
GO:0141108	transporter regulator activity	31/4284	170/18639	0.182352941176471	0.793388531883341	0.944904546573192	1
GO:0005452	solute:inorganic anion antiporter activity	4/4284	31/18639	0.129032258064516	0.561398753049607	0.947977510302601	1
GO:0001848	complement binding	3/4284	25/18639	0.12	0.522100840336134	0.948728823730262	1
GO:0008483	transaminase activity	3/4284	25/18639	0.12	0.522100840336134	0.948728823730262	1
GO:0015662	P-type ion transporter activity	3/4284	25/18639	0.12	0.522100840336134	0.948728823730262	1
GO:0140358	P-type transmembrane transporter activity	3/4284	25/18639	0.12	0.522100840336134	0.948728823730262	1
GO:0022829	wide pore channel activity	5/4284	37/18639	0.135135135135135	0.587951396774926	0.949169633118626	1
GO:0043394	proteoglycan binding	5/4284	37/18639	0.135135135135135	0.587951396774926	0.949169633118626	1
GO:0005200	structural constituent of cytoskeleton	19/4284	112/18639	0.169642857142857	0.738088985594238	0.952679484006861	1
GO:0022840	leak channel activity	2/4284	19/18639	0.105263157894737	0.457983193277311	0.953393702923293	1
GO:0022842	narrow pore channel activity	2/4284	19/18639	0.105263157894737	0.457983193277311	0.953393702923293	1
GO:0031420	alkali metal ion binding	2/4284	19/18639	0.105263157894737	0.457983193277311	0.953393702923293	1
GO:0042834	peptidoglycan binding	2/4284	19/18639	0.105263157894737	0.457983193277311	0.953393702923293	1
GO:0043395	heparan sulfate proteoglycan binding	2/4284	19/18639	0.105263157894737	0.457983193277311	0.953393702923293	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	9/4284	60/18639	0.15	0.652626050420168	0.953949906028795	1
GO:0005004	GPI-linked ephrin receptor activity	7/4284	49/18639	0.142857142857143	0.621548619447779	0.953996551882507	1
GO:0005008	hepatocyte growth factor receptor activity	7/4284	49/18639	0.142857142857143	0.621548619447779	0.953996551882507	1
GO:0005009	insulin receptor activity	7/4284	49/18639	0.142857142857143	0.621548619447779	0.953996551882507	1
GO:0005011	macrophage colony-stimulating factor receptor activity	7/4284	49/18639	0.142857142857143	0.621548619447779	0.953996551882507	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	7/4284	49/18639	0.142857142857143	0.621548619447779	0.953996551882507	1
GO:0005020	stem cell factor receptor activity	7/4284	49/18639	0.142857142857143	0.621548619447779	0.953996551882507	1
GO:0008288	boss receptor activity	7/4284	49/18639	0.142857142857143	0.621548619447779	0.953996551882507	1
GO:0036332	placental growth factor receptor activity	7/4284	49/18639	0.142857142857143	0.621548619447779	0.953996551882507	1
GO:0038062	protein tyrosine kinase collagen receptor activity	7/4284	49/18639	0.142857142857143	0.621548619447779	0.953996551882507	1
GO:0060175	brain-derived neurotrophic factor receptor activity	7/4284	49/18639	0.142857142857143	0.621548619447779	0.953996551882507	1
GO:0008081	phosphoric diester hydrolase activity	14/4284	87/18639	0.160919540229885	0.700135226504395	0.956241361464965	1
GO:0004032	aldose reductase (NADPH) activity	1/4284	12/18639	0.0833333333333333	0.362570028011204	0.956498131707565	1
GO:0004126	cytidine deaminase activity	1/4284	12/18639	0.0833333333333333	0.362570028011204	0.956498131707565	1
GO:0005436	sodium:phosphate symporter activity	1/4284	12/18639	0.0833333333333333	0.362570028011204	0.956498131707565	1
GO:0008179	adenylate cyclase binding	1/4284	12/18639	0.0833333333333333	0.362570028011204	0.956498131707565	1
GO:0008504	monoamine transmembrane transporter activity	1/4284	12/18639	0.0833333333333333	0.362570028011204	0.956498131707565	1
GO:0015166	polyol transmembrane transporter activity	1/4284	12/18639	0.0833333333333333	0.362570028011204	0.956498131707565	1
GO:0016208	AMP binding	1/4284	12/18639	0.0833333333333333	0.362570028011204	0.956498131707565	1
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/4284	12/18639	0.0833333333333333	0.362570028011204	0.956498131707565	1
GO:0005126	cytokine receptor binding	52/4284	275/18639	0.189090909090909	0.82270435446906	0.956978684486827	1
GO:0005227	calcium-activated cation channel activity	3/4284	26/18639	0.115384615384615	0.502020038784745	0.957690081847951	1
GO:0019955	cytokine binding	25/4284	144/18639	0.173611111111111	0.755354225023343	0.959887970722554	1
GO:0005006	epidermal growth factor receptor activity	7/4284	50/18639	0.14	0.609117647058824	0.960272378479484	1
GO:0005007	fibroblast growth factor receptor activity	7/4284	50/18639	0.14	0.609117647058824	0.960272378479484	1
GO:0005017	platelet-derived growth factor receptor activity	7/4284	50/18639	0.14	0.609117647058824	0.960272378479484	1
GO:0005019	platelet-derived growth factor beta-receptor activity	7/4284	50/18639	0.14	0.609117647058824	0.960272378479484	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/4284	20/18639	0.1	0.435084033613445	0.962508655035065	1
GO:0010851	cyclase regulator activity	2/4284	20/18639	0.1	0.435084033613445	0.962508655035065	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/4284	20/18639	0.1	0.435084033613445	0.962508655035065	1
GO:0019842	vitamin binding	26/4284	150/18639	0.173333333333333	0.754145658263305	0.963345413867826	1
GO:0019956	chemokine binding	4/4284	33/18639	0.121212121212121	0.527374586198116	0.963440401551789	1
GO:0030296	protein tyrosine kinase activator activity	4/4284	33/18639	0.121212121212121	0.527374586198116	0.963440401551789	1
GO:0042562	hormone binding	15/4284	94/18639	0.159574468085106	0.694283032361881	0.964202353829022	1
GO:0005104	fibroblast growth factor receptor binding	3/4284	27/18639	0.111111111111111	0.483426704014939	0.965165259445397	1
GO:0005010	insulin-like growth factor receptor activity	7/4284	51/18639	0.137254901960784	0.59717416378316	0.965763139771349	1
GO:0005030	neurotrophin receptor activity	7/4284	51/18639	0.137254901960784	0.59717416378316	0.965763139771349	1
GO:0004465	lipoprotein lipase activity	1/4284	13/18639	0.0769230769230769	0.334680025856496	0.966503070976626	1
GO:0017154	semaphorin receptor activity	1/4284	13/18639	0.0769230769230769	0.334680025856496	0.966503070976626	1
GO:0030955	potassium ion binding	1/4284	13/18639	0.0769230769230769	0.334680025856496	0.966503070976626	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/4284	13/18639	0.0769230769230769	0.334680025856496	0.966503070976626	1
GO:1901338	catecholamine binding	1/4284	13/18639	0.0769230769230769	0.334680025856496	0.966503070976626	1
GO:0003777	microtubule motor activity	10/4284	68/18639	0.147058823529412	0.639829461196243	0.967187255284963	1
GO:0015144	carbohydrate transmembrane transporter activity	5/4284	40/18639	0.125	0.543855042016807	0.969044457209048	1
GO:1901681	sulfur compound binding	51/4284	275/18639	0.185454545454545	0.806883116883117	0.969153064293449	1
GO:0008376	acetylgalactosaminyltransferase activity	4/4284	34/18639	0.117647058823529	0.511863568956995	0.969456305031172	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	4/4284	34/18639	0.117647058823529	0.511863568956995	0.969456305031172	1
GO:0036122	BMP binding	2/4284	21/18639	0.0952380952380952	0.414365746298519	0.969896754256091	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	7/4284	52/18639	0.134615384615385	0.585690045248869	0.97055415491522	1
GO:0051119	sugar transmembrane transporter activity	3/4284	28/18639	0.107142857142857	0.466161464585834	0.97138151303238	1
GO:0042287	MHC protein binding	5/4284	41/18639	0.121951219512195	0.530590284894446	0.973874649814308	1
GO:0004065	arylsulfatase activity	1/4284	14/18639	0.0714285714285714	0.31077430972389	0.974207400619927	1
GO:0005313	L-glutamate transmembrane transporter activity	1/4284	14/18639	0.0714285714285714	0.31077430972389	0.974207400619927	1
GO:0005344	oxygen carrier activity	1/4284	14/18639	0.0714285714285714	0.31077430972389	0.974207400619927	1
GO:0008195	phosphatidate phosphatase activity	1/4284	14/18639	0.0714285714285714	0.31077430972389	0.974207400619927	1
GO:0008494	translation activator activity	1/4284	14/18639	0.0714285714285714	0.31077430972389	0.974207400619927	1
GO:0008559	ABC-type xenobiotic transporter activity	1/4284	14/18639	0.0714285714285714	0.31077430972389	0.974207400619927	1
GO:0016530	metallochaperone activity	1/4284	14/18639	0.0714285714285714	0.31077430972389	0.974207400619927	1
GO:0031404	chloride ion binding	1/4284	14/18639	0.0714285714285714	0.31077430972389	0.974207400619927	1
GO:0043176	amine binding	1/4284	14/18639	0.0714285714285714	0.31077430972389	0.974207400619927	1
GO:0008237	metallopeptidase activity	32/4284	184/18639	0.173913043478261	0.756667884545122	0.974269745959492	1
GO:0004181	metallocarboxypeptidase activity	3/4284	29/18639	0.103448275862069	0.450086931324254	0.976536052715779	1
GO:0005416	amino acid:monoatomic cation symporter activity	3/4284	29/18639	0.103448275862069	0.450086931324254	0.976536052715779	1
GO:0051861	glycolipid binding	3/4284	29/18639	0.103448275862069	0.450086931324254	0.976536052715779	1
GO:0008307	structural constituent of muscle	5/4284	42/18639	0.119047619047619	0.517957182873149	0.977995558840423	1
GO:0042056	chemoattractant activity	5/4284	42/18639	0.119047619047619	0.517957182873149	0.977995558840423	1
GO:0004129	cytochrome-c oxidase activity	1/4284	15/18639	0.0666666666666667	0.290056022408964	0.980140044686732	1
GO:0004953	icosanoid receptor activity	1/4284	15/18639	0.0666666666666667	0.290056022408964	0.980140044686732	1
GO:0010181	FMN binding	1/4284	15/18639	0.0666666666666667	0.290056022408964	0.980140044686732	1
GO:0015250	water channel activity	1/4284	15/18639	0.0666666666666667	0.290056022408964	0.980140044686732	1
GO:0034483	heparan sulfate sulfotransferase activity	1/4284	15/18639	0.0666666666666667	0.290056022408964	0.980140044686732	1
GO:0047372	monoacylglycerol lipase activity	1/4284	15/18639	0.0666666666666667	0.290056022408964	0.980140044686732	1
GO:0031406	carboxylic acid binding	32/4284	187/18639	0.171122994652406	0.74452882757381	0.98031290858706	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/4284	23/18639	0.0869565217391304	0.378333942272561	0.980688552044261	1
GO:0016849	phosphorus-oxygen lyase activity	2/4284	23/18639	0.0869565217391304	0.378333942272561	0.980688552044261	1
GO:0016917	GABA receptor activity	2/4284	23/18639	0.0869565217391304	0.378333942272561	0.980688552044261	1
GO:0099186	structural constituent of postsynapse	2/4284	23/18639	0.0869565217391304	0.378333942272561	0.980688552044261	1
GO:0001965	G-protein alpha-subunit binding	3/4284	30/18639	0.1	0.435084033613445	0.980798839697248	1
GO:0022839	monoatomic ion-gated channel activity	3/4284	30/18639	0.1	0.435084033613445	0.980798839697248	1
GO:0005518	collagen binding	10/4284	72/18639	0.138888888888889	0.604283380018674	0.980974024759317	1
GO:0023023	MHC protein complex binding	4/4284	37/18639	0.108108108108108	0.470361117419941	0.982408054263409	1
GO:0016500	protein-hormone receptor activity	9/4284	67/18639	0.134328358208955	0.58444123918224	0.98266708826443	1
GO:0050840	extracellular matrix binding	9/4284	67/18639	0.134328358208955	0.58444123918224	0.98266708826443	1
GO:0043177	organic acid binding	32/4284	189/18639	0.169312169312169	0.736650215641812	0.983604712256921	1
GO:0015179	L-amino acid transmembrane transporter activity	8/4284	62/18639	0.129032258064516	0.561398753049607	0.98451842170732	1
GO:0015149	hexose transmembrane transporter activity	2/4284	24/18639	0.0833333333333333	0.362570028011204	0.984567326746246	1
GO:0019957	C-C chemokine binding	2/4284	24/18639	0.0833333333333333	0.362570028011204	0.984567326746246	1
GO:0055056	D-glucose transmembrane transporter activity	2/4284	24/18639	0.0833333333333333	0.362570028011204	0.984567326746246	1
GO:0015378	sodium:chloride symporter activity	1/4284	16/18639	0.0625	0.271927521008403	0.984708346263302	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/4284	16/18639	0.0625	0.271927521008403	0.984708346263302	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/4284	16/18639	0.0625	0.271927521008403	0.984708346263302	1
GO:0016722	oxidoreductase activity, acting on metal ions	1/4284	16/18639	0.0625	0.271927521008403	0.984708346263302	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/4284	16/18639	0.0625	0.271927521008403	0.984708346263302	1
GO:1901682	sulfur compound transmembrane transporter activity	8/4284	63/18639	0.126984126984127	0.552487661731359	0.986720661544903	1
GO:0042605	peptide antigen binding	5/4284	45/18639	0.111111111111111	0.483426704014939	0.986999834832839	1
GO:0015106	bicarbonate transmembrane transporter activity	3/4284	32/18639	0.09375	0.407891281512605	0.987209678088155	1
GO:0005178	integrin binding	26/4284	161/18639	0.161490683229814	0.702620178506185	0.987403789788951	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/4284	39/18639	0.102564102564103	0.446240034475329	0.987935363059216	1
GO:0008484	sulfuric ester hydrolase activity	1/4284	17/18639	0.0588235294117647	0.255931784478497	0.988226009615502	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/4284	17/18639	0.0588235294117647	0.255931784478497	0.988226009615502	1
GO:0030548	acetylcholine receptor regulator activity	1/4284	17/18639	0.0588235294117647	0.255931784478497	0.988226009615502	1
GO:0045236	CXCR chemokine receptor binding	1/4284	17/18639	0.0588235294117647	0.255931784478497	0.988226009615502	1
GO:0070492	oligosaccharide binding	1/4284	17/18639	0.0588235294117647	0.255931784478497	0.988226009615502	1
GO:0004620	phospholipase activity	16/4284	109/18639	0.146788990825688	0.638655462184874	0.988633478142866	1
GO:0015085	calcium ion transmembrane transporter activity	23/4284	147/18639	0.156462585034014	0.680743726061853	0.989430149867354	1
GO:0008066	glutamate receptor activity	2/4284	26/18639	0.0769230769230769	0.334680025856496	0.990183188018262	1
GO:0015145	monosaccharide transmembrane transporter activity	2/4284	26/18639	0.0769230769230769	0.334680025856496	0.990183188018262	1
GO:0030247	polysaccharide binding	2/4284	26/18639	0.0769230769230769	0.334680025856496	0.990183188018262	1
GO:0043548	phosphatidylinositol 3-kinase binding	2/4284	26/18639	0.0769230769230769	0.334680025856496	0.990183188018262	1
GO:0015459	potassium channel regulator activity	7/4284	59/18639	0.11864406779661	0.516201395812562	0.990259959620962	1
GO:0008146	sulfotransferase activity	6/4284	53/18639	0.113207547169811	0.492547962581259	0.990450986818222	1
GO:0005372	water transmembrane transporter activity	1/4284	18/18639	0.0555555555555556	0.24171335200747	0.990934621730591	1
GO:0015373	monoatomic anion:sodium symporter activity	1/4284	18/18639	0.0555555555555556	0.24171335200747	0.990934621730591	1
GO:0022851	GABA-gated chloride ion channel activity	1/4284	18/18639	0.0555555555555556	0.24171335200747	0.990934621730591	1
GO:0032393	MHC class I receptor activity	1/4284	18/18639	0.0555555555555556	0.24171335200747	0.990934621730591	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/4284	18/18639	0.0555555555555556	0.24171335200747	0.990934621730591	1
GO:0099602	neurotransmitter receptor regulator activity	1/4284	18/18639	0.0555555555555556	0.24171335200747	0.990934621730591	1
GO:0090482	vitamin transmembrane transporter activity	3/4284	34/18639	0.0882352941176471	0.383897676717746	0.991534699358949	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/4284	27/18639	0.0740740740740741	0.322284469343293	0.992184622304091	1
GO:0004890	GABA-A receptor activity	1/4284	19/18639	0.0526315789473684	0.228991596638655	0.993020228330996	1
GO:0005229	intracellularly calcium-gated chloride channel activity	1/4284	19/18639	0.0526315789473684	0.228991596638655	0.993020228330996	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/4284	19/18639	0.0526315789473684	0.228991596638655	0.993020228330996	1
GO:0034987	immunoglobulin receptor binding	1/4284	19/18639	0.0526315789473684	0.228991596638655	0.993020228330996	1
GO:0141147	intracellularly calcium-gated channel activity	1/4284	19/18639	0.0526315789473684	0.228991596638655	0.993020228330996	1
GO:0005343	organic acid:sodium symporter activity	3/4284	35/18639	0.0857142857142857	0.372929171668667	0.993128277632688	1
GO:0005242	inward rectifier potassium channel activity	2/4284	28/18639	0.0714285714285714	0.31077430972389	0.993784861478838	1
GO:0050698	proteoglycan sulfotransferase activity	2/4284	28/18639	0.0714285714285714	0.31077430972389	0.993784861478838	1
GO:0005253	monoatomic anion channel activity	14/4284	103/18639	0.135922330097087	0.59137635636779	0.994099191782662	1
GO:0170055	lipid transmembrane transporter activity	6/4284	56/18639	0.107142857142857	0.466161464585834	0.994335497161436	1
GO:0005262	calcium channel activity	19/4284	131/18639	0.145038167938931	0.631037911347745	0.994346226030735	1
GO:0005326	neurotransmitter transmembrane transporter activity	1/4284	20/18639	0.05	0.217542016806723	0.994626100609729	1
GO:0030627	pre-mRNA 5'-splice site binding	1/4284	20/18639	0.05	0.217542016806723	0.994626100609729	1
GO:0048020	CCR chemokine receptor binding	5/4284	50/18639	0.1	0.435084033613445	0.994770464383165	1
GO:0003785	actin monomer binding	2/4284	29/18639	0.0689655172413793	0.300057954216169	0.995062551016842	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	4/4284	44/18639	0.0909090909090909	0.395530939648587	0.995431246596365	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	8/4284	70/18639	0.114285714285714	0.497238895558223	0.995652685860614	1
GO:0005272	sodium channel activity	5/4284	51/18639	0.0980392156862745	0.426552974130829	0.995660710363486	1
GO:0015125	bile acid transmembrane transporter activity	1/4284	21/18639	0.0476190476190476	0.20718287314926	0.995862567927411	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/4284	30/18639	0.0666666666666667	0.290056022408964	0.99608138753967	1
GO:0048019	receptor antagonist activity	2/4284	30/18639	0.0666666666666667	0.290056022408964	0.99608138753967	1
GO:0005501	retinoid binding	3/4284	38/18639	0.0789473684210526	0.343487394957983	0.996353498022006	1
GO:0019840	isoprenoid binding	3/4284	38/18639	0.0789473684210526	0.343487394957983	0.996353498022006	1
GO:0016298	lipase activity	18/4284	130/18639	0.138461538461538	0.602424046541694	0.996798504716064	1
GO:0005243	gap junction channel activity	1/4284	22/18639	0.0454545454545455	0.197765469824293	0.996814590647304	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/4284	31/18639	0.0645161290322581	0.280699376524803	0.996892834218005	1
GO:0004175	endopeptidase activity	71/4284	405/18639	0.175308641975309	0.762739910779127	0.997206696894772	1
GO:0016493	C-C chemokine receptor activity	1/4284	23/18639	0.0434782608695652	0.189166971136281	0.997547592401988	1
GO:0004222	metalloendopeptidase activity	14/4284	110/18639	0.127272727272727	0.553743315508021	0.997780963609091	1
GO:0061134	peptidase regulator activity	35/4284	226/18639	0.154867256637168	0.673802706923477	0.998068146591843	1
GO:0004806	triacylglycerol lipase activity	1/4284	24/18639	0.0416666666666667	0.181285014005602	0.998111951778325	1
GO:0015171	amino acid transmembrane transporter activity	12/4284	102/18639	0.117647058823529	0.511863568956995	0.99873758147597	1
GO:0008509	monoatomic anion transmembrane transporter activity	20/4284	149/18639	0.134228187919463	0.584005414246235	0.998847286904649	1
GO:0001637	G protein-coupled chemoattractant receptor activity	1/4284	26/18639	0.0384615384615385	0.167340012928248	0.998880992445564	1
GO:0004950	chemokine receptor activity	1/4284	26/18639	0.0384615384615385	0.167340012928248	0.998880992445564	1
GO:0042379	chemokine receptor binding	7/4284	72/18639	0.0972222222222222	0.422998366013072	0.998970914845636	1
GO:0030547	signaling receptor inhibitor activity	3/4284	44/18639	0.0681818181818182	0.29664820473644	0.999004200299745	1
GO:0008395	steroid hydroxylase activity	1/4284	27/18639	0.037037037037037	0.161142234671646	0.999138545143313	1
GO:0015252	proton channel activity	1/4284	27/18639	0.037037037037037	0.161142234671646	0.999138545143313	1
GO:0008009	chemokine activity	3/4284	45/18639	0.0666666666666667	0.290056022408964	0.999200655795885	1
GO:0017046	peptide hormone binding	4/4284	53/18639	0.0754716981132075	0.328365308387506	0.999266690140502	1
GO:0015101	organic cation transmembrane transporter activity	8/4284	81/18639	0.0987654320987654	0.429712625791057	0.99933850660076	1
GO:0008514	organic anion transmembrane transporter activity	41/4284	269/18639	0.152416356877323	0.663139233388523	0.999421246490205	1
GO:0001664	G protein-coupled receptor binding	46/4284	297/18639	0.154882154882155	0.673867526808703	0.999512239044541	1
GO:0071855	neuropeptide receptor binding	2/4284	40/18639	0.05	0.217542016806723	0.999627844010319	1
GO:0030246	carbohydrate binding	42/4284	280/18639	0.15	0.652626050420168	0.999687522428953	1
GO:0005184	neuropeptide hormone activity	1/4284	31/18639	0.032258064516129	0.140349688262402	0.999697475345941	1
GO:0042910	xenobiotic transmembrane transporter activity	1/4284	32/18639	0.03125	0.135963760504202	0.999767123648713	1
GO:0160041	neuropeptide activity	1/4284	32/18639	0.03125	0.135963760504202	0.999767123648713	1
GO:0015020	glucuronosyltransferase activity	1/4284	34/18639	0.0294117647058824	0.127965892239249	0.999862014429022	1
GO:0019825	oxygen binding	1/4284	34/18639	0.0294117647058824	0.127965892239249	0.999862014429022	1
GO:0015294	solute:monoatomic cation symporter activity	12/4284	116/18639	0.103448275862069	0.450086931324254	0.999867959013008	1
GO:0022804	active transmembrane transporter activity	74/4284	457/18639	0.161925601750547	0.704512439549124	0.999884792257419	1
GO:0003730	mRNA 3'-UTR binding	37/4284	262/18639	0.141221374045802	0.614431650522805	0.999888957834472	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/4284	46/18639	0.0434782608695652	0.189166971136281	0.999911913659594	1
GO:0004497	monooxygenase activity	10/4284	106/18639	0.0943396226415094	0.410456635484382	0.999920089499174	1
GO:0015291	secondary active transmembrane transporter activity	41/4284	287/18639	0.142857142857143	0.621548619447779	0.999923458321446	1
GO:0099095	ligand-gated monoatomic anion channel activity	2/4284	47/18639	0.0425531914893617	0.185142141963168	0.999930831122903	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/4284	56/18639	0.0535714285714286	0.233080732292917	0.999932273688225	1
GO:0046906	tetrapyrrole binding	17/4284	152/18639	0.111842105263158	0.486607142857143	0.999940820097361	1
GO:0015293	symporter activity	16/4284	146/18639	0.10958904109589	0.476804420398296	0.999941990711355	1
GO:0046943	carboxylic acid transmembrane transporter activity	23/4284	188/18639	0.122340425531915	0.532283658144109	0.999942505180855	1
GO:0004867	serine-type endopeptidase inhibitor activity	8/4284	95/18639	0.0842105263157895	0.366386554621849	0.999949497764594	1
GO:0005342	organic acid transmembrane transporter activity	23/4284	189/18639	0.121693121693122	0.529467342492553	0.999950168499109	1
GO:0061135	endopeptidase regulator activity	22/4284	184/18639	0.119565217391304	0.520209170624772	0.999956189196937	1
GO:0020037	heme binding	15/4284	142/18639	0.105633802816901	0.459595810155048	0.999959300169921	1
GO:0004866	endopeptidase inhibitor activity	18/4284	161/18639	0.111801242236025	0.486429354350436	0.999962318113392	1
GO:0005254	chloride channel activity	6/4284	83/18639	0.072289156626506	0.314518578515744	0.999967790675189	1
GO:0015081	sodium ion transmembrane transporter activity	18/4284	164/18639	0.109756097560976	0.477531256405001	0.999976422402559	1
GO:0008227	G protein-coupled amine receptor activity	1/4284	41/18639	0.024390243902439	0.106118056978889	0.999977915239737	1
GO:0015108	chloride transmembrane transporter activity	11/4284	121/18639	0.0909090909090909	0.395530939648587	0.999982110488935	1
GO:0008201	heparin binding	19/4284	172/18639	0.11046511627907	0.480616083642759	0.99998240496143	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/4284	53/18639	0.0377358490566038	0.164182654193753	0.999983915869016	1
GO:0015370	solute:sodium symporter activity	5/4284	79/18639	0.0632911392405063	0.275369641527497	0.999984774415047	1
GO:0022824	transmitter-gated monoatomic ion channel activity	3/4284	63/18639	0.0476190476190476	0.20718287314926	0.999986459973811	1
GO:0022835	transmitter-gated channel activity	3/4284	63/18639	0.0476190476190476	0.20718287314926	0.999986459973811	1
GO:0017171	serine hydrolase activity	23/4284	198/18639	0.116161616161616	0.505400645106527	0.999986632746837	1
GO:0005245	voltage-gated calcium channel activity	1/4284	43/18639	0.0232558139534884	0.101182333398476	0.999986917967042	1
GO:0030414	peptidase inhibitor activity	18/4284	169/18639	0.106508875739645	0.46340311272438	0.999989347411979	1
GO:0004896	cytokine receptor activity	7/4284	96/18639	0.0729166666666667	0.317248774509804	0.999989676383916	1
GO:0008236	serine-type peptidase activity	22/4284	194/18639	0.11340206185567	0.493394264922464	0.999990128266213	1
GO:0005539	glycosaminoglycan binding	30/4284	242/18639	0.12396694214876	0.539360372248073	0.999991035407458	1
GO:0008083	growth factor activity	16/4284	162/18639	0.0987654320987654	0.429712625791057	0.999995789862121	1
GO:0004252	serine-type endopeptidase activity	18/4284	176/18639	0.102272727272727	0.44497230710466	0.999996586776657	1
GO:0098960	postsynaptic neurotransmitter receptor activity	3/4284	69/18639	0.0434782608695652	0.189166971136281	0.999996656243658	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/4284	73/18639	0.0410958904109589	0.178801657649361	0.999998694539972	1
GO:0015103	inorganic anion transmembrane transporter activity	15/4284	165/18639	0.0909090909090909	0.395530939648587	0.999999191510612	1
GO:0015079	potassium ion transmembrane transporter activity	14/4284	160/18639	0.0875	0.380698529411765	0.999999403347286	1
GO:0001653	peptide receptor activity	9/4284	128/18639	0.0703125	0.305918461134454	0.99999967606143	1
GO:0005201	extracellular matrix structural constituent	14/4284	168/18639	0.0833333333333333	0.362570028011204	0.999999861959569	1
GO:0022832	voltage-gated channel activity	15/4284	175/18639	0.0857142857142857	0.372929171668667	0.999999865960131	1
GO:0008528	G protein-coupled peptide receptor activity	7/4284	122/18639	0.0573770491803279	0.249638379942141	0.999999953726052	1
GO:0030594	neurotransmitter receptor activity	4/4284	97/18639	0.0412371134020619	0.179416096335441	0.999999958913593	1
GO:0005244	voltage-gated monoatomic ion channel activity	13/4284	173/18639	0.0751445086705202	0.326941759362705	0.99999998580664	1
GO:0005249	voltage-gated potassium channel activity	3/4284	98/18639	0.0306122448979592	0.133188989881667	0.99999999673479	1
GO:0099094	ligand-gated monoatomic cation channel activity	7/4284	136/18639	0.0514705882352941	0.223940311418685	0.999999997775098	1
GO:0005267	potassium channel activity	5/4284	124/18639	0.0403225806451613	0.175437110328002	0.999999999343121	1
GO:0046873	metal ion transmembrane transporter activity	54/4284	450/18639	0.12	0.522100840336134	0.999999999353087	1
GO:0140375	immune receptor activity	8/4284	156/18639	0.0512820512820513	0.223120017237664	0.999999999827275	1
GO:0005125	cytokine activity	18/4284	234/18639	0.0769230769230769	0.334680025856496	0.999999999891017	1
GO:0005261	monoatomic cation channel activity	34/4284	341/18639	0.0997067448680352	0.433808127356514	0.9999999999021	1
GO:0005179	hormone activity	4/4284	132/18639	0.0303030303030303	0.131843646549529	0.999999999989729	1
GO:0022843	voltage-gated monoatomic cation channel activity	5/4284	143/18639	0.034965034965035	0.152127284480226	0.999999999992224	1
GO:0005216	monoatomic ion channel activity	46/4284	448/18639	0.102678571428571	0.446738070228091	0.999999999999418	1
GO:0003823	antigen binding	7/4284	174/18639	0.0402298850574713	0.175033806626099	0.999999999999564	1
GO:0015276	ligand-gated monoatomic ion channel activity	8/4284	186/18639	0.043010752688172	0.187132917683202	0.999999999999783	1
GO:0022834	ligand-gated channel activity	8/4284	188/18639	0.0425531914893617	0.185142141963168	0.999999999999862	1
GO:0022836	gated channel activity	21/4284	318/18639	0.0660377358490566	0.287319644839068	0.999999999999999	1
GO:0030371	translation repressor activity	12/4284	329/18639	0.0364741641337386	0.158693264539858	1	1
GO:0045182	translation regulator activity	15/4284	356/18639	0.0421348314606742	0.183321924275328	1	1