ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0019787	ubiquitin-like protein transferase activity	216/4868	479/18639	0.450939457202505	1.72659419531584	9.20795412020818e-20	1.21452914845546e-16
GO:0016755	aminoacyltransferase activity	217/4868	496/18639	0.4375	1.67513609285127	5.76029863171362e-18	3.79891694761513e-15
GO:0004842	ubiquitin-protein transferase activity	199/4868	449/18639	0.443207126948775	1.69698801133899	2.6341762714727e-17	1.15815950069083e-14
GO:0003712	transcription coregulator activity	211/4868	495/18639	0.426262626262626	1.63210950922537	5.25168973837261e-16	1.73174469122837e-13
GO:0043021	ribonucleoprotein complex binding	96/4868	177/18639	0.542372881355932	2.07668203278415	1.45170225185727e-15	3.82959054039948e-13
GO:0003697	single-stranded DNA binding	72/4868	121/18639	0.59504132231405	2.27834330456277	8.56050370122588e-15	1.88188406365282e-12
GO:0140098	catalytic activity, acting on RNA	167/4868	387/18639	0.431524547803618	1.65225678851923	1.71190614834192e-13	3.22572029951857e-11
GO:0140097	catalytic activity, acting on DNA	148/4868	336/18639	0.44047619047619	1.68653157647611	5.91540865315997e-13	9.75303001689751e-11
GO:0140104	molecular carrier activity	117/4868	249/18639	0.469879518072289	1.79911346289018	8.77065036088053e-13	1.28538753622238e-10
GO:0008094	ATP-dependent activity, acting on DNA	100/4868	210/18639	0.476190476190476	1.82327737997418	1.4788343361395e-11	1.95058248936799e-09
GO:0003713	transcription coactivator activity	116/4868	256/18639	0.453125	1.73496238188168	2.0927195763426e-11	2.50936101926899e-09
GO:0031072	heat shock protein binding	70/4868	131/18639	0.534351145038168	2.04596774699392	2.44173696687988e-11	2.68387588276214e-09
GO:0016887	ATP hydrolysis activity	168/4868	417/18639	0.402877697841727	1.54257136607887	1.25798540147965e-10	1.27637134196281e-08
GO:0061659	ubiquitin-like protein ligase activity	152/4868	372/18639	0.408602150537634	1.56448962281655	2.89705088327121e-10	2.72943579645337e-08
GO:0043022	ribosome binding	60/4868	112/18639	0.535714285714286	2.05118705247095	5.55549861534557e-10	4.68430066993866e-08
GO:0042393	histone binding	109/4868	247/18639	0.441295546558704	1.68966879464004	5.68224493699913e-10	4.68430066993866e-08
GO:0140597	protein carrier chaperone	88/4868	188/18639	0.468085106382979	1.79224287137887	7.24855755265859e-10	5.62402788938628e-08
GO:0008135	translation factor activity, RNA binding	48/4868	83/18639	0.578313253012048	2.21429349278791	9.59959095790903e-10	7.03436692971223e-08
GO:0003684	damaged DNA binding	44/4868	74/18639	0.594594594594595	2.2766328366164	1.41493739565968e-09	9.822644341448e-08
GO:0180051	translation factor activity	48/4868	84/18639	0.571428571428571	2.18793285596901	1.67361041659535e-09	1.10374606974463e-07
GO:0140297	DNA-binding transcription factor binding	186/4868	488/18639	0.381147540983607	1.4593691488072	2.64493369092145e-09	1.59759462774397e-07
GO:0140713	histone chaperone activity	78/4868	164/18639	0.475609756097561	1.82105387097421	2.66467640715447e-09	1.59759462774397e-07
GO:0061630	ubiquitin protein ligase activity	142/4868	353/18639	0.402266288951841	1.5402303532813	3.7947692511392e-09	2.17621767054461e-07
GO:0140674	ATP-dependent histone chaperone activity	73/4868	152/18639	0.480263157894737	1.83887119967132	5.02406858421695e-09	2.76114435940923e-07
GO:0004386	helicase activity	74/4868	155/18639	0.47741935483871	1.8279826119225	5.48150586551216e-09	2.89204249464422e-07
GO:0140658	ATP-dependent chromatin remodeler activity	75/4868	158/18639	0.474683544303797	1.81750751484767	5.95210883773997e-09	3.01955059883809e-07
GO:0044389	ubiquitin-like protein ligase binding	131/4868	322/18639	0.406832298136646	1.55771306593446	6.66277263784086e-09	3.25488781826374e-07
GO:0000510	H3-H4 histone complex chaperone activity	72/4868	151/18639	0.47682119205298	1.82569231690129	9.37514169844263e-09	3.98897158072446e-07
GO:0140584	chromatin extrusion motor activity	72/4868	151/18639	0.47682119205298	1.82569231690129	9.37514169844263e-09	3.98897158072446e-07
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	72/4868	151/18639	0.47682119205298	1.82569231690129	9.37514169844263e-09	3.98897158072446e-07
GO:0140849	ATP-dependent H2AZ histone chaperone activity	72/4868	151/18639	0.47682119205298	1.82569231690129	9.37514169844263e-09	3.98897158072446e-07
GO:0051059	NF-kappaB binding	24/4868	32/18639	0.75	2.87166187345933	1.03136158532479e-08	4.25114353451061e-07
GO:0003689	DNA clamp loader activity	75/4868	160/18639	0.46875	1.79478867091208	1.18037194452913e-08	4.71791089343614e-07
GO:0015616	DNA translocase activity	72/4868	152/18639	0.473684210526316	1.81368118323747	1.32911075012458e-08	5.15616788063035e-07
GO:0016741	transferase activity, transferring one-carbon groups	94/4868	215/18639	0.437209302325581	1.6740230456135	1.49243897237099e-08	5.62436287016382e-07
GO:0070063	RNA polymerase binding	36/4868	59/18639	0.610169491525424	2.33626728688216	1.68004427139299e-08	6.15549553879822e-07
GO:0061775	cohesin loader activity	72/4868	153/18639	0.470588235294118	1.80182705785683	1.87332033794567e-08	6.67813385337931e-07
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	138/4868	349/18639	0.39541547277937	1.51399938314188	2.23381005584408e-08	7.7536722727851e-07
GO:0031625	ubiquitin protein ligase binding	122/4868	302/18639	0.403973509933775	1.54676710181915	3.50626169871793e-08	1.18583568733563e-06
GO:0003743	translation initiation factor activity	32/4868	51/18639	0.627450980392157	2.40243607714244	4.03183886776469e-08	1.32949886664541e-06
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	76/4868	167/18639	0.455089820359281	1.74248544816694	4.57960578075175e-08	1.47329268897843e-06
GO:0008168	methyltransferase activity	88/4868	204/18639	0.431372549019608	1.65167480303543	8.97315364591331e-08	2.80461909351767e-06
GO:0003735	structural constituent of ribosome	78/4868	175/18639	0.445714285714286	1.70658762765583	9.14318582420468e-08	2.80461909351767e-06
GO:0016779	nucleotidyltransferase activity	64/4868	136/18639	0.470588235294118	1.80182705785683	1.13053180129433e-07	3.38902601342549e-06
GO:0140030	modification-dependent protein binding	77/4868	173/18639	0.445086705202312	1.70418469561748	1.18432205395612e-07	3.47137953148472e-06
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	35/4868	60/18639	0.583333333333333	2.23351479046836	1.31437866421845e-07	3.7688379524003e-06
GO:0051087	protein-folding chaperone binding	63/4868	134/18639	0.470149253731343	1.8001462490342	1.47717373470133e-07	4.14551522568308e-06
GO:0051082	unfolded protein binding	58/4868	121/18639	0.479338842975207	1.83533210645334	1.98961523172182e-07	5.46729685550225e-06
GO:0060589	nucleoside-triphosphatase regulator activity	177/4868	490/18639	0.361224489795918	1.38308612680898	4.83791312075679e-07	1.30228722577106e-05
GO:0001098	basal transcription machinery binding	34/4868	60/18639	0.566666666666667	2.16970008216927	5.14193736353485e-07	1.32984615343186e-05
GO:0001099	basal RNA polymerase II transcription machinery binding	34/4868	60/18639	0.566666666666667	2.16970008216927	5.14193736353485e-07	1.32984615343186e-05
GO:0140142	nucleocytoplasmic carrier activity	22/4868	32/18639	0.6875	2.63235671733772	5.3374275121512e-07	1.35385901702451e-05
GO:0061650	ubiquitin-like protein conjugating enzyme activity	26/4868	41/18639	0.634146341463415	2.42807182796561	5.6162040490239e-07	1.39769304540802e-05
GO:0019783	ubiquitin-like protein peptidase activity	59/4868	127/18639	0.464566929133858	1.77877218408504	6.00546572011714e-07	1.46689060830269e-05
GO:0030695	GTPase regulator activity	176/4868	489/18639	0.359918200408998	1.37808449823815	6.8189377472363e-07	1.63530525247358e-05
GO:0004527	exonuclease activity	43/4868	84/18639	0.511904761904762	1.96002318347224	7.86162356692273e-07	1.85169312228055e-05
GO:0003678	DNA helicase activity	39/4868	74/18639	0.527027027027027	2.01792455972818	9.73584376067525e-07	2.23666335833039e-05
GO:0004674	protein serine/threonine kinase activity	158/4868	433/18639	0.364896073903002	1.39714419093633	9.8352141609676e-07	2.23666335833039e-05
GO:0002039	p53 binding	37/4868	69/18639	0.536231884057971	2.05316887571005	1.05222752634219e-06	2.35235272414466e-05
GO:0043175	RNA polymerase core enzyme binding	26/4868	42/18639	0.619047619047619	2.37026059396643	1.1076571006902e-06	2.43499952635062e-05
GO:1990518	single-stranded 3'-5' DNA helicase activity	28/4868	47/18639	0.595744680851064	2.28103638175493	1.30780853876734e-06	2.82786797153134e-05
GO:0004532	RNA exonuclease activity	25/4868	40/18639	0.625	2.3930515612161	1.37991508967339e-06	2.93565806980517e-05
GO:0003725	double-stranded RNA binding	39/4868	75/18639	0.52	1.9910188989318	1.51909767050351e-06	3.18046004348274e-05
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	24/4868	38/18639	0.631578947368421	2.41824157764996	1.70965088469154e-06	3.52348362016897e-05
GO:0003727	single-stranded RNA binding	44/4868	89/18639	0.49438202247191	1.89293067314173	2.00895810888349e-06	4.07663960864203e-05
GO:0000993	RNA polymerase II complex binding	23/4868	36/18639	0.638888888888889	2.44623048479869	2.10449477573835e-06	4.1430277749237e-05
GO:0005484	SNAP receptor activity	23/4868	36/18639	0.638888888888889	2.44623048479869	2.10449477573835e-06	4.1430277749237e-05
GO:0106310	protein serine kinase activity	134/4868	361/18639	0.371191135734072	1.4212472430048	2.28487108674345e-06	4.43197788737442e-05
GO:0043138	3'-5' DNA helicase activity	28/4868	48/18639	0.583333333333333	2.23351479046836	2.35716753916282e-06	4.50594780312428e-05
GO:0017116	single-stranded DNA helicase activity	32/4868	58/18639	0.551724137931034	2.11248689541835	2.45579554845225e-06	4.62742046915503e-05
GO:0000287	magnesium ion binding	92/4868	230/18639	0.4	1.53155299917831	2.64738130964011e-06	4.91816330621874e-05
GO:0004518	nuclease activity	85/4868	209/18639	0.406698564593301	1.55720101591096	2.86576953862806e-06	5.24993058534779e-05
GO:0008234	cysteine-type peptidase activity	77/4868	187/18639	0.411764705882353	1.57659867562473	4.7814073241507e-06	8.63928254870518e-05
GO:0061749	forked DNA-dependent helicase activity	27/4868	47/18639	0.574468085106383	2.19957079669225	5.33790201849317e-06	9.51444967890878e-05
GO:0140662	ATP-dependent protein folding chaperone	24/4868	40/18639	0.6	2.29732949876746	6.28916585158763e-06	0.000110605463443255
GO:0015631	tubulin binding	139/4868	385/18639	0.361038961038961	1.3823757589986	8.14920077885664e-06	0.000141431524043578
GO:0008408	3'-5' exonuclease activity	31/4868	58/18639	0.53448275862069	2.04647167993653	8.48830968037791e-06	0.000145403642446993
GO:0009378	four-way junction helicase activity	27/4868	48/18639	0.5625	2.15374640509449	9.17027492048939e-06	0.000153108767343361
GO:0036121	double-stranded DNA helicase activity	27/4868	48/18639	0.5625	2.15374640509449	9.17027492048939e-06	0.000153108767343361
GO:0032404	mismatch repair complex binding	10/4868	11/18639	0.909090909090909	3.48080227085979	1.23080383444405e-05	0.000202928782203962
GO:0044183	protein folding chaperone	37/4868	75/18639	0.493333333333333	1.88891536565325	1.36029198968721e-05	0.000221509275851534
GO:0008173	RNA methyltransferase activity	34/4868	67/18639	0.507462686567164	1.94301499895755	1.39578680102673e-05	0.000224517413482226
GO:0017069	snRNA binding	29/4868	54/18639	0.537037037037037	2.05625171185976	1.45948544382086e-05	0.0002319350964337
GO:0001222	transcription corepressor binding	27/4868	49/18639	0.551020408163265	2.10979239682726	1.53545139103169e-05	0.000238265927620095
GO:0060590	ATPase regulator activity	27/4868	49/18639	0.551020408163265	2.10979239682726	1.53545139103169e-05	0.000238265927620095
GO:0035173	histone kinase activity	130/4868	360/18639	0.361111111111111	1.38265201314708	1.55799507564435e-05	0.0002389529656715
GO:0051020	GTPase binding	116/4868	315/18639	0.368253968253968	1.4100011738467	1.61044998402187e-05	0.000244159026313201
GO:0141003	histone H2AX kinase activity	128/4868	354/18639	0.361581920903955	1.38445468852276	1.68022345018006e-05	0.000251842583044033
GO:0140852	histone ubiquitin ligase activity	11/4868	13/18639	0.846153846153846	3.23982365210796	1.72872603614362e-05	0.000256201083334094
GO:0140857	histone H3T45 kinase activity	94/4868	246/18639	0.382113821138211	1.46306892197928	1.90562677948537e-05	0.000279280191349023
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	93/4868	243/18639	0.382716049382716	1.46537478316443	1.95796666052288e-05	0.000281384807821798
GO:0051536	iron-sulfur cluster binding	37/4868	76/18639	0.486842105263158	1.86406121610518	1.98768170380708e-05	0.000281384807821798
GO:0004402	histone acetyltransferase activity	24/4868	42/18639	0.571428571428571	2.18793285596901	2.00490221537182e-05	0.000281384807821798
GO:0061733	protein-lysine-acetyltransferase activity	26/4868	47/18639	0.553191489361702	2.11810521162957	2.00532008606891e-05	0.000281384807821798
GO:0000175	3'-5'-RNA exonuclease activity	21/4868	35/18639	0.6	2.29732949876746	2.3953423654165e-05	0.000317533079669011
GO:0010485	histone H4 acetyltransferase activity	21/4868	35/18639	0.6	2.29732949876746	2.3953423654165e-05	0.000317533079669011
GO:0061631	ubiquitin conjugating enzyme activity	21/4868	35/18639	0.6	2.29732949876746	2.3953423654165e-05	0.000317533079669011
GO:0051537	2 iron, 2 sulfur cluster binding	18/4868	28/18639	0.642857142857143	2.46142446296514	2.44350855570326e-05	0.000317533079669011
GO:0004715	non-membrane spanning protein tyrosine kinase activity	25/4868	45/18639	0.555555555555556	2.1271569433032	2.6180098018636e-05	0.000317533079669011
GO:0140996	histone H3 kinase activity	128/4868	357/18639	0.358543417366947	1.37282061550997	2.65212527637837e-05	0.000317533079669011
GO:0031267	small GTPase binding	105/4868	283/18639	0.371024734982332	1.42061011407882	2.77378072197118e-05	0.000317533079669011
GO:0004676	3-phosphoinositide-dependent protein kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0004711	ribosomal protein S6 kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0035175	histone H3S10 kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0035979	histone H2AXS139 kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0044022	histone H3S28 kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0044023	histone H4S1 kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0044024	histone H2AS1 kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0044025	histone H2BS14 kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0072354	histone H3T3 kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0072371	histone H2AS121 kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0072518	Rho-dependent protein serine/threonine kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0140823	histone H2BS36 kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0140855	histone H3S57 kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0140995	histone H2A kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0140997	histone H4 kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0140998	histone H2B kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:1990244	histone H2AT120 kinase activity	93/4868	245/18639	0.379591836734694	1.45341254003656	2.84070533744831e-05	0.000317533079669011
GO:0051540	metal cluster binding	37/4868	77/18639	0.480519480519481	1.83985262888303	2.86949496422609e-05	0.000318055786370943
GO:0004677	DNA-dependent protein kinase activity	93/4868	246/18639	0.378048780487805	1.4475043589795	3.40908642170029e-05	0.000374715415851891
GO:0030544	Hsp70 protein binding	27/4868	51/18639	0.529411764705882	2.02705544008894	4.01124409673351e-05	0.000437258757321611
GO:0035402	histone H3T11 kinase activity	93/4868	247/18639	0.376518218623482	1.44164401744517	4.08131157896816e-05	0.000437662599403171
GO:0035403	histone H3T6 kinase activity	93/4868	247/18639	0.376518218623482	1.44164401744517	4.08131157896816e-05	0.000437662599403171
GO:0140101	catalytic activity, acting on a tRNA	58/4868	139/18639	0.41726618705036	1.59766320058169	4.2880646881806e-05	0.000454071287095255
GO:0098505	G-rich strand telomeric DNA binding	9/4868	10/18639	0.9	3.44599424815119	4.30317747436747e-05	0.000454071287095255
GO:0004679	AMP-activated protein kinase activity	93/4868	248/18639	0.375	1.43583093672966	4.87441988051909e-05	0.0005102666525718
GO:0005525	GTP binding	133/4868	378/18639	0.351851851851852	1.34719939742536	5.17310622181063e-05	0.000537269850910883
GO:0005096	GTPase activator activity	100/4868	271/18639	0.3690036900369	1.41287177045969	5.44743855252765e-05	0.000560191384036107
GO:0016922	nuclear receptor binding	57/4868	137/18639	0.416058394160584	1.59303870352488	5.4787481835222e-05	0.000560191384036107
GO:0043047	single-stranded telomeric DNA binding	10/4868	12/18639	0.833333333333333	3.19073541495481	5.63855825467882e-05	0.00057209679522472
GO:0030983	mismatched DNA binding	11/4868	14/18639	0.785714285714286	3.00840767695739	6.14766629759484e-05	0.000614300897464211
GO:0098847	sequence-specific single stranded DNA binding	11/4868	14/18639	0.785714285714286	3.00840767695739	6.14766629759484e-05	0.000614300897464211
GO:0004197	cysteine-type endopeptidase activity	40/4868	88/18639	0.454545454545455	1.74040113542989	6.85561853979521e-05	0.000679891793533074
GO:0022884	macromolecule transmembrane transporter activity	19/4868	32/18639	0.59375	2.2733989831553	7.18009699253679e-05	0.000706757308444479
GO:0017056	structural constituent of nuclear pore	16/4868	25/18639	0.64	2.45048479868529	7.57764408813911e-05	0.000740363892759666
GO:0101005	deubiquitinase activity	49/4868	115/18639	0.426086956521739	1.63143689042907	8.71982641421085e-05	0.000845694929437067
GO:0034212	protein N-acetyltransferase activity	27/4868	53/18639	0.509433962264151	1.95056278197237	9.62673427887325e-05	0.000920120472016943
GO:0140296	general transcription initiation factor binding	27/4868	53/18639	0.509433962264151	1.95056278197237	9.62673427887325e-05	0.000920120472016943
GO:0046966	nuclear thyroid hormone receptor binding	17/4868	28/18639	0.607142857142857	2.32467865946707	0.000117458767594568	0.0011145907514909
GO:0042162	telomeric DNA binding	21/4868	38/18639	0.552631578947368	2.11596138044371	0.000127588163913241	0.00120206277286832
GO:0016407	acetyltransferase activity	42/4868	96/18639	0.4375	1.67513609285127	0.000133455740389501	0.00124842639414008
GO:0140034	methylation-dependent protein binding	35/4868	76/18639	0.460526315789474	1.76330115036976	0.000138262054190718	0.00128427922167294
GO:0032182	ubiquitin-like protein binding	50/4868	120/18639	0.416666666666667	1.5953677074774	0.000145978457298496	0.0013464726236134
GO:0044390	ubiquitin-like protein conjugating enzyme binding	20/4868	36/18639	0.555555555555556	2.1271569433032	0.000167225515394146	0.00153173926947832
GO:0035064	methylated histone binding	34/4868	74/18639	0.459459459459459	1.75921628283995	0.000181047630697321	0.00163780581016823
GO:0070990	snRNP binding	9/4868	11/18639	0.818181818181818	3.13272204377381	0.000181288588540228	0.00163780581016823
GO:0004540	RNA nuclease activity	50/4868	121/18639	0.413223140495868	1.58218285039081	0.000186336536995269	0.00167195845099836
GO:0008017	microtubule binding	99/4868	276/18639	0.358695652173913	1.37340350469794	0.000201336160989023	0.00179434051584136
GO:0016853	isomerase activity	69/4868	180/18639	0.383333333333333	1.46773829087921	0.000205537001080129	0.00181948526459523
GO:0008080	N-acetyltransferase activity	32/4868	69/18639	0.463768115942029	1.77571362223572	0.000224205868812297	0.00197151693975613
GO:0008276	protein methyltransferase activity	41/4868	95/18639	0.431578947368421	1.65246507806081	0.000228174186022879	0.00199312418121972
GO:0008170	N-methyltransferase activity	42/4868	98/18639	0.428571428571429	1.64094964197676	0.000231636170546846	0.00201005334836375
GO:0019207	kinase regulator activity	102/4868	287/18639	0.355400696864112	1.36078750798073	0.000240692015681499	0.00207498541623462
GO:0019887	protein kinase regulator activity	92/4868	255/18639	0.36078431372549	1.3814007443569	0.000263665860699369	0.00225828097573031
GO:0008320	protein transmembrane transporter activity	16/4868	27/18639	0.592592592592593	2.26896740619008	0.000277629092808179	0.00236253402202573
GO:0030515	snoRNA binding	18/4868	32/18639	0.5625	2.15374640509449	0.000286956434085249	0.0024122596168798
GO:0003714	transcription corepressor activity	76/4868	204/18639	0.372549019607843	1.42644642080333	0.000287130219749908	0.0024122596168798
GO:0061608	nuclear import signal receptor activity	13/4868	20/18639	0.65	2.48877362366475	0.000292941061520396	0.00244550164648989
GO:0051219	phosphoprotein binding	40/4868	93/18639	0.43010752688172	1.64683118191216	0.000294855758409439	0.00244600468768585
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	24/4868	48/18639	0.5	1.91444124897288	0.000334400943148638	0.00275671777508159
GO:0016791	phosphatase activity	97/4868	273/18639	0.355311355311355	1.36044542967304	0.000340138142664019	0.00278659757871951
GO:0140767	enzyme-substrate adaptor activity	55/4868	139/18639	0.39568345323741	1.51502544882746	0.000347032959670498	0.00282553378892214
GO:0043995	histone H4K5 acetyltransferase activity	17/4868	30/18639	0.566666666666667	2.16970008216927	0.000375588632389277	0.00300243276437246
GO:0043996	histone H4K8 acetyltransferase activity	17/4868	30/18639	0.566666666666667	2.16970008216927	0.000375588632389277	0.00300243276437246
GO:0043997	histone H4K12 acetyltransferase activity	17/4868	30/18639	0.566666666666667	2.16970008216927	0.000375588632389277	0.00300243276437246
GO:0030145	manganese ion binding	31/4868	68/18639	0.455882352941176	1.74551996229881	0.000406621755481464	0.0032309282860244
GO:0003688	DNA replication origin binding	11/4868	16/18639	0.6875	2.63235671733772	0.000429347898103886	0.00339107711137141
GO:0003924	GTPase activity	114/4868	331/18639	0.344410876132931	1.31870877572755	0.00043798346487714	0.00343869160817231
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	51/4868	128/18639	0.3984375	1.52557037027527	0.000460886417194541	0.00359709576496805
GO:0016763	pentosyltransferase activity	24/4868	49/18639	0.489795918367347	1.87537101940201	0.000494322480460904	0.00383536089251725
GO:0140318	protein transporter activity	21/4868	41/18639	0.51219512195122	1.96113493797222	0.000513781579904912	0.00396302867774608
GO:0005049	nuclear export signal receptor activity	9/4868	12/18639	0.75	2.87166187345933	0.000555997606520548	0.00423908001734452
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	9/4868	12/18639	0.75	2.87166187345933	0.000555997606520548	0.00423908001734452
GO:0032356	oxidized DNA binding	8/4868	10/18639	0.8	3.06310599835661	0.000572987779726388	0.00431869075119489
GO:1905394	retromer complex binding	8/4868	10/18639	0.8	3.06310599835661	0.000572987779726388	0.00431869075119489
GO:0140457	protein demethylase activity	17/4868	31/18639	0.548387096774194	2.099709756938	0.000630172310760514	0.00470137998905498
GO:0004843	cysteine-type deubiquitinase activity	44/4868	108/18639	0.407407407407407	1.55991509175568	0.000630890263883799	0.00470137998905498
GO:0019902	phosphatase binding	70/4868	190/18639	0.368421052631579	1.41064092029581	0.000697817061701156	0.00517090283361699
GO:0042826	histone deacetylase binding	50/4868	127/18639	0.393700787401575	1.50743405430936	0.000719098326956281	0.00529883068857729
GO:0051879	Hsp90 protein binding	21/4868	42/18639	0.5	1.91444124897288	0.000776528094154258	0.0056902253121637
GO:0008186	ATP-dependent activity, acting on RNA	34/4868	79/18639	0.430379746835443	1.64787348012856	0.000800725250457694	0.0058064465288845
GO:0019001	guanyl nucleotide binding	133/4868	400/18639	0.3325	1.27310343056697	0.000805594931604143	0.0058064465288845
GO:0032561	guanyl ribonucleotide binding	133/4868	400/18639	0.3325	1.27310343056697	0.000805594931604143	0.0058064465288845
GO:0004721	phosphoprotein phosphatase activity	65/4868	175/18639	0.371428571428571	1.42215635637986	0.000829958822012195	0.00589775945318528
GO:0010484	histone H3 acetyltransferase activity	16/4868	29/18639	0.551724137931034	2.11248689541835	0.000831247243211931	0.00589775945318528
GO:0005085	guanyl-nucleotide exchange factor activity	82/4868	230/18639	0.356521739130435	1.36507984709371	0.000831677982026127	0.00589775945318528
GO:0051787	misfolded protein binding	11/4868	17/18639	0.647058823529412	2.47751220455314	0.000929123682111336	0.00655355153318103
GO:0019843	rRNA binding	29/4868	65/18639	0.446153846153846	1.70827065292965	0.000948443980206107	0.00665424260580774
GO:0140223	general transcription initiation factor activity	30/4868	68/18639	0.441176470588235	1.68921286674078	0.000977850668969671	0.00682425943053437
GO:0015036	disulfide oxidoreductase activity	20/4868	40/18639	0.5	1.91444124897288	0.00103005056239805	0.00715071943054228
GO:0003724	RNA helicase activity	33/4868	77/18639	0.428571428571429	1.64094964197676	0.00103647218868158	0.00715762731346076
GO:0140463	chromatin-protein adaptor activity	25/4868	54/18639	0.462962962962963	1.772630786086	0.00108852536009045	0.00740559128919441
GO:0004407	histone deacetylase activity	13/4868	22/18639	0.590909090909091	2.26252147605886	0.00108922267634853	0.00740559128919441
GO:0033558	protein lysine deacetylase activity	13/4868	22/18639	0.590909090909091	2.26252147605886	0.00108922267634853	0.00740559128919441
GO:0001671	ATPase activator activity	15/4868	27/18639	0.555555555555556	2.1271569433032	0.00109666614009872	0.00741796225020618
GO:0042809	nuclear vitamin D receptor binding	10/4868	15/18639	0.666666666666667	2.55258833196385	0.0011478013068295	0.00772423430463321
GO:0140566	histone reader activity	18/4868	35/18639	0.514285714285714	1.96913957037211	0.00119932939244643	0.0080300277595779
GO:0031624	ubiquitin conjugating enzyme binding	16/4868	30/18639	0.533333333333333	2.04207066557108	0.00135199994129496	0.00896124584205049
GO:0032452	histone demethylase activity	16/4868	30/18639	0.533333333333333	2.04207066557108	0.00135199994129496	0.00896124584205049
GO:0046975	histone H3K36 methyltransferase activity	9/4868	13/18639	0.692307692307692	2.65076480627015	0.00138688724407137	0.00905596175707987
GO:0140666	annealing activity	9/4868	13/18639	0.692307692307692	2.65076480627015	0.00138688724407137	0.00905596175707987
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	9/4868	13/18639	0.692307692307692	2.65076480627015	0.00138688724407137	0.00905596175707987
GO:0000339	RNA cap binding	12/4868	20/18639	0.6	2.29732949876746	0.00141340596627351	0.0091386395564449
GO:0043024	ribosomal small subunit binding	12/4868	20/18639	0.6	2.29732949876746	0.00141340596627351	0.0091386395564449
GO:0008139	nuclear localization sequence binding	14/4868	25/18639	0.56	2.14417419884963	0.00144694156374425	0.00930983376867643
GO:0001046	core promoter sequence-specific DNA binding	21/4868	44/18639	0.477272727272727	1.82742119220139	0.00166004316504061	0.01057776296951
GO:0016790	thiolester hydrolase activity	21/4868	44/18639	0.477272727272727	1.82742119220139	0.00166004316504061	0.01057776296951
GO:0019903	protein phosphatase binding	54/4868	144/18639	0.375	1.43583093672966	0.0017030105624689	0.0107993794802715
GO:0043539	protein serine/threonine kinase activator activity	31/4868	73/18639	0.424657534246575	1.62596380049752	0.00173385799316201	0.0109423860908167
GO:0036408	histone H3K14 acetyltransferase activity	15/4868	28/18639	0.535714285714286	2.05118705247095	0.00179529300202839	0.0112227083870874
GO:0141052	histone H3 demethylase activity	15/4868	28/18639	0.535714285714286	2.05118705247095	0.00179529300202839	0.0112227083870874
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	11/4868	18/18639	0.611111111111111	2.33987263763353	0.00182629624556672	0.0113626639052005
GO:0035591	signaling adaptor activity	49/4868	129/18639	0.37984496124031	1.45438172402591	0.00199189467561392	0.0123347843996937
GO:0160215	deacylase activity	28/4868	65/18639	0.430769230769231	1.64936476834587	0.00219937547843417	0.0135559638133396
GO:1990841	promoter-specific chromatin binding	29/4868	68/18639	0.426470588235294	1.63290577118275	0.00222487988176533	0.0136493793676673
GO:0000049	tRNA binding	33/4868	80/18639	0.4125	1.57941403040263	0.00223819843004407	0.013667517264945
GO:0043023	ribosomal large subunit binding	10/4868	16/18639	0.625	2.3930515612161	0.00234522365470552	0.0142482737828567
GO:0051539	4 iron, 4 sulfur cluster binding	21/4868	45/18639	0.466666666666667	1.78681183237469	0.00235490802476327	0.0142482737828567
GO:0050681	nuclear androgen receptor binding	14/4868	26/18639	0.538461538461538	2.06170596043234	0.00238645357013013	0.014373206662108
GO:0015035	protein-disulfide reductase activity	17/4868	34/18639	0.5	1.91444124897288	0.00241964671142416	0.0144412398749705
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	17/4868	34/18639	0.5	1.91444124897288	0.00241964671142416	0.0144412398749705
GO:0140693	molecular condensate scaffold activity	22/4868	48/18639	0.458333333333333	1.75490447822514	0.0024878406960256	0.014781359811071
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	26/4868	60/18639	0.433333333333333	1.6591824157765	0.00281670732728917	0.0166602554470602
GO:0032451	demethylase activity	19/4868	40/18639	0.475	1.81871918652424	0.00291597437690862	0.0170184522262941
GO:0061791	GTPase motor activity	19/4868	40/18639	0.475	1.81871918652424	0.00291597437690862	0.0170184522262941
GO:1990606	membrane scission GTPase motor activity	19/4868	40/18639	0.475	1.81871918652424	0.00291597437690862	0.0170184522262941
GO:0008474	palmitoyl-(protein) hydrolase activity	9/4868	14/18639	0.642857142857143	2.46142446296514	0.00298363533085444	0.0172605921113904
GO:0098599	palmitoyl hydrolase activity	9/4868	14/18639	0.642857142857143	2.46142446296514	0.00298363533085444	0.0172605921113904
GO:0045296	cadherin binding	110/4868	334/18639	0.329341317365269	1.26100920591028	0.00305779865750897	0.017612386153949
GO:0004722	protein serine/threonine phosphatase activity	40/4868	103/18639	0.388349514563107	1.48694465939641	0.00310773052785051	0.0178221589836296
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	46/4868	122/18639	0.377049180327869	1.44367700742217	0.00317193247201336	0.0181115971021023
GO:0140036	ubiquitin-modified protein reader activity	11/4868	19/18639	0.578947368421053	2.21672144617913	0.0033184039260162	0.018866270596618
GO:0043015	gamma-tubulin binding	17/4868	35/18639	0.485714285714286	1.85974292757366	0.00357216862379201	0.0201379625460102
GO:0042054	histone methyltransferase activity	28/4868	67/18639	0.417910447761194	1.60012999914151	0.00373375794858953	0.0201379625460102
GO:0000340	RNA 7-methylguanosine cap binding	8/4868	12/18639	0.666666666666667	2.55258833196385	0.00374056165562736	0.0201379625460102
GO:0000995	RNA polymerase III general transcription initiation factor activity	8/4868	12/18639	0.666666666666667	2.55258833196385	0.00374056165562736	0.0201379625460102
GO:0005095	GTPase inhibitor activity	8/4868	12/18639	0.666666666666667	2.55258833196385	0.00374056165562736	0.0201379625460102
GO:0016273	arginine N-methyltransferase activity	8/4868	12/18639	0.666666666666667	2.55258833196385	0.00374056165562736	0.0201379625460102
GO:0016274	protein-arginine N-methyltransferase activity	8/4868	12/18639	0.666666666666667	2.55258833196385	0.00374056165562736	0.0201379625460102
GO:0034452	dynactin binding	8/4868	12/18639	0.666666666666667	2.55258833196385	0.00374056165562736	0.0201379625460102
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	8/4868	12/18639	0.666666666666667	2.55258833196385	0.00374056165562736	0.0201379625460102
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	8/4868	12/18639	0.666666666666667	2.55258833196385	0.00374056165562736	0.0201379625460102
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	8/4868	12/18639	0.666666666666667	2.55258833196385	0.00374056165562736	0.0201379625460102
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	8/4868	12/18639	0.666666666666667	2.55258833196385	0.00374056165562736	0.0201379625460102
GO:1990817	poly(A) RNA polymerase activity	8/4868	12/18639	0.666666666666667	2.55258833196385	0.00374056165562736	0.0201379625460102
GO:0001727	lipid kinase activity	19/4868	41/18639	0.463414634146341	1.77436018197487	0.0041200899367405	0.0220910513274826
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	12/4868	22/18639	0.545454545454545	2.08848136251587	0.00423192328533178	0.0225076887635186
GO:0140517	protein-RNA adaptor activity	12/4868	22/18639	0.545454545454545	2.08848136251587	0.00423192328533178	0.0225076887635186
GO:0070566	adenylyltransferase activity	15/4868	30/18639	0.5	1.91444124897288	0.00430439840308282	0.0228012108179367
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	10/4868	17/18639	0.588235294117647	2.25228382232104	0.00436822361555436	0.0229549280833315
GO:0004659	prenyltransferase activity	10/4868	17/18639	0.588235294117647	2.25228382232104	0.00436822361555436	0.0229549280833315
GO:0140938	histone H3 methyltransferase activity	21/4868	47/18639	0.446808510638298	1.71077728631619	0.00448916058402919	0.0234968365489465
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	7/4868	10/18639	0.7	2.68021774856204	0.00457598537013001	0.0237626956818956
GO:0008641	ubiquitin-like modifier activating enzyme activity	7/4868	10/18639	0.7	2.68021774856204	0.00457598537013001	0.0237626956818956
GO:0071889	14-3-3 protein binding	16/4868	33/18639	0.484848484848485	1.85642787779189	0.00475930084575852	0.024617716923747
GO:0045309	protein phosphorylated amino acid binding	25/4868	59/18639	0.423728813559322	1.62240783811261	0.00480787990373037	0.0247718499727358
GO:0001221	transcription coregulator binding	43/4868	115/18639	0.373913043478261	1.43166910792755	0.00504226094357622	0.02581261042344
GO:0017025	TBP-class protein binding	13/4868	25/18639	0.52	1.9910188989318	0.00504901705022557	0.02581261042344
GO:0016829	lyase activity	69/4868	200/18639	0.345	1.32096446179129	0.00509756750147175	0.0259601989746766
GO:0052745	inositol phosphate phosphatase activity	11/4868	20/18639	0.55	2.10588537387017	0.00564673476570171	0.0285365638159408
GO:0140939	histone H4 methyltransferase activity	11/4868	20/18639	0.55	2.10588537387017	0.00564673476570171	0.0285365638159408
GO:0031386	protein tag activity	9/4868	15/18639	0.6	2.29732949876746	0.00573738636689186	0.028540074897103
GO:0061578	K63-linked deubiquitinase activity	9/4868	15/18639	0.6	2.29732949876746	0.00573738636689186	0.028540074897103
GO:0140776	protein-containing complex destabilizing activity	9/4868	15/18639	0.6	2.29732949876746	0.00573738636689186	0.028540074897103
GO:0141047	molecular tag activity	9/4868	15/18639	0.6	2.29732949876746	0.00573738636689186	0.028540074897103
GO:0097718	disordered domain specific binding	14/4868	28/18639	0.5	1.91444124897288	0.00575561783368414	0.028540074897103
GO:0043130	ubiquitin binding	38/4868	100/18639	0.38	1.45497534921939	0.00593540069870511	0.0293213240509065
GO:0009055	electron transfer activity	43/4868	116/18639	0.370689655172414	1.41932713285921	0.00602308052711287	0.0296434448330667
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	23/4868	54/18639	0.425925925925926	1.63082032319912	0.00620604739402876	0.0304303959580815
GO:0140789	histone phosphatase activity	49/4868	136/18639	0.360294117647059	1.37952384117164	0.00668091918578674	0.0325709751502842
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	12/4868	23/18639	0.521739130434783	1.99767782501518	0.0067660706529021	0.0325709751502842
GO:0008171	O-methyltransferase activity	12/4868	23/18639	0.521739130434783	1.99767782501518	0.0067660706529021	0.0325709751502842
GO:0044013	histone H2B acetyltransferase activity	12/4868	23/18639	0.521739130434783	1.99767782501518	0.0067660706529021	0.0325709751502842
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	12/4868	23/18639	0.521739130434783	1.99767782501518	0.0067660706529021	0.0325709751502842
GO:0008175	tRNA methyltransferase activity	16/4868	34/18639	0.470588235294118	1.80182705785683	0.0068389934096113	0.0326834503886859
GO:0052866	phosphatidylinositol phosphate phosphatase activity	16/4868	34/18639	0.470588235294118	1.80182705785683	0.0068389934096113	0.0326834503886859
GO:0004535	poly(A)-specific ribonuclease activity	8/4868	13/18639	0.615384615384615	2.35623538335124	0.00750644071411697	0.0353606975068581
GO:0009982	pseudouridine synthase activity	8/4868	13/18639	0.615384615384615	2.35623538335124	0.00750644071411697	0.0353606975068581
GO:0019104	DNA N-glycosylase activity	8/4868	13/18639	0.615384615384615	2.35623538335124	0.00750644071411697	0.0353606975068581
GO:0051011	microtubule minus-end binding	8/4868	13/18639	0.615384615384615	2.35623538335124	0.00750644071411697	0.0353606975068581
GO:0000400	four-way junction DNA binding	10/4868	18/18639	0.555555555555556	2.1271569433032	0.00754563282803889	0.0354188245558125
GO:0016278	lysine N-methyltransferase activity	28/4868	70/18639	0.4	1.53155299917831	0.00765846174838245	0.0358154039418783
GO:0004529	DNA exonuclease activity	13/4868	26/18639	0.5	1.91444124897288	0.00771158053032102	0.0358154039418783
GO:0052742	phosphatidylinositol kinase activity	13/4868	26/18639	0.5	1.91444124897288	0.00771158053032102	0.0358154039418783
GO:0004712	protein serine/threonine/tyrosine kinase activity	19/4868	43/18639	0.441860465116279	1.6918318014179	0.00775979585147835	0.0359128797477191
GO:0106222	lncRNA binding	14/4868	29/18639	0.482758620689655	1.84842603349106	0.00848787525107973	0.0391451309656439
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	32/4868	83/18639	0.385542168674699	1.47619566185861	0.00862588785915978	0.0396430177220618
GO:0031369	translation initiation factor binding	15/4868	32/18639	0.46875	1.79478867091208	0.00910841121906591	0.0415709148717922
GO:0070717	poly-purine tract binding	15/4868	32/18639	0.46875	1.79478867091208	0.00910841121906591	0.0415709148717922
GO:0031491	nucleosome binding	29/4868	74/18639	0.391891891891892	1.50050800595172	0.00933260398528448	0.042447257436518
GO:0034511	U3 snoRNA binding	7/4868	11/18639	0.636363636363636	2.43656158960185	0.0097533015944676	0.0440812073633155
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	27/4868	68/18639	0.397058823529412	1.5202915800667	0.00975869033365285	0.0440812073633155
GO:0000062	fatty-acyl-CoA binding	9/4868	16/18639	0.5625	2.15374640509449	0.0100987384254172	0.0454421209309122
GO:0008137	NADH dehydrogenase (ubiquinone) activity	18/4868	41/18639	0.439024390243902	1.68097280397619	0.0102049915783117	0.0454421209309122
GO:0001091	RNA polymerase II general transcription initiation factor binding	12/4868	24/18639	0.5	1.91444124897288	0.0103562035085489	0.0454421209309122
GO:0043998	histone H2A acetyltransferase activity	12/4868	24/18639	0.5	1.91444124897288	0.0103562035085489	0.0454421209309122
GO:0048027	mRNA 5'-UTR binding	12/4868	24/18639	0.5	1.91444124897288	0.0103562035085489	0.0454421209309122
GO:0140612	DNA damage sensor activity	12/4868	24/18639	0.5	1.91444124897288	0.0103562035085489	0.0454421209309122
GO:0003954	NADH dehydrogenase activity	19/4868	44/18639	0.431818181818182	1.6533810786584	0.0103700366946206	0.0454421209309122
GO:0019205	nucleobase-containing compound kinase activity	19/4868	44/18639	0.431818181818182	1.6533810786584	0.0103700366946206	0.0454421209309122
GO:0043014	alpha-tubulin binding	19/4868	44/18639	0.431818181818182	1.6533810786584	0.0103700366946206	0.0454421209309122
GO:0016251	RNA polymerase II general transcription initiation factor activity	22/4868	53/18639	0.415094339622642	1.58934745197749	0.010452286689988	0.0455002182973406
GO:0016860	intramolecular oxidoreductase activity	22/4868	53/18639	0.415094339622642	1.58934745197749	0.010452286689988	0.0455002182973406
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	13/4868	27/18639	0.481481481481481	1.84353601752944	0.0113665538490382	0.04931738331211
GO:0016410	N-acyltransferase activity	35/4868	94/18639	0.372340425531915	1.42564773859683	0.0114494757894334	0.0495142903811892
GO:0019003	GDP binding	29/4868	75/18639	0.386666666666667	1.48050123253903	0.0114928290132587	0.0495393512042097
GO:0016279	protein-lysine N-methyltransferase activity	27/4868	69/18639	0.391304347826087	1.49825836876139	0.0121202234879566	0.0520252034849629
GO:0035925	mRNA 3'-UTR AU-rich region binding	14/4868	30/18639	0.466666666666667	1.78681183237469	0.012148417493077	0.0520252034849629
GO:0120227	acyl-CoA binding	10/4868	19/18639	0.526315789473684	2.0152013147083	0.0122425538302863	0.0520900919424119
GO:1990380	K48-linked deubiquitinase activity	10/4868	19/18639	0.526315789473684	2.0152013147083	0.0122425538302863	0.0520900919424119
GO:0019239	deaminase activity	15/4868	33/18639	0.454545454545455	1.74040113542989	0.0127326698634887	0.0540012590030277
GO:0042578	phosphoric ester hydrolase activity	114/4868	363/18639	0.31404958677686	1.20245896629702	0.0131436645204118	0.0549073014215065
GO:0055106	ubiquitin-protein transferase regulator activity	16/4868	36/18639	0.444444444444444	1.70172555464256	0.013148690865095	0.0549073014215065
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	31/4868	82/18639	0.378048780487805	1.4475043589795	0.0131582268159932	0.0549073014215065
GO:0016776	phosphotransferase activity, phosphate group as acceptor	17/4868	39/18639	0.435897435897436	1.66900006320713	0.0134229350485953	0.0549073014215065
GO:0016830	carbon-carbon lyase activity	21/4868	51/18639	0.411764705882353	1.57659867562473	0.0135186538730554	0.0549073014215065
GO:0032454	histone H3K9 demethylase activity	8/4868	14/18639	0.571428571428571	2.18793285596901	0.0135368478918003	0.0549073014215065
GO:0008649	rRNA methyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0032931	histone H3K56 acetyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0034062	5'-3' RNA polymerase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0043992	histone H3K9 acetyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0043993	histone H3K18 acetyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0043994	histone H3K23 acetyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0043999	histone H2AK5 acetyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0044012	histone H2AK9 acetyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0044014	histone H2BK5 acetyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0044015	histone H2BK12 acetyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0044016	histone H3K4 acetyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0044017	histone H3K27 acetyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0044018	histone H3K36 acetyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0046972	histone H4K16 acetyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0070034	telomerase RNA binding	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0097747	RNA polymerase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0140035	ubiquitin-like protein reader activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0140908	histone H3K122 acetyltransferase activity	11/4868	22/18639	0.5	1.91444124897288	0.0139453722336654	0.0549073014215065
GO:0019209	kinase activator activity	51/4868	148/18639	0.344594594594595	1.31941221212996	0.0147613868231444	0.0579472298206176
GO:0017124	SH3 domain binding	41/4868	115/18639	0.356521739130435	1.36507984709371	0.014870663256921	0.0582029817088392
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	12/4868	25/18639	0.48	1.83786359901397	0.0152551448546935	0.0593555636086747
GO:0047617	fatty acyl-CoA hydrolase activity	12/4868	25/18639	0.48	1.83786359901397	0.0152551448546935	0.0593555636086747
GO:0004536	DNA nuclease activity	25/4868	64/18639	0.390625	1.49565722576007	0.0157725678686448	0.0611882853492428
GO:0051019	mitogen-activated protein kinase binding	13/4868	28/18639	0.464285714285714	1.77769544547482	0.0162293650623451	0.0627757551825021
GO:0032183	SUMO binding	9/4868	17/18639	0.529411764705882	2.02705544008894	0.0165455675865128	0.0636256666081936
GO:1901567	fatty acid derivative binding	9/4868	17/18639	0.529411764705882	2.02705544008894	0.0165455675865128	0.0636256666081936
GO:0019210	kinase inhibitor activity	33/4868	90/18639	0.366666666666667	1.40392358258011	0.0175645390229691	0.0673477528235358
GO:0019213	deacetylase activity	16/4868	37/18639	0.432432432432432	1.65573297208466	0.0176581484588614	0.0675104284557629
GO:0003995	acyl-CoA dehydrogenase activity	7/4868	12/18639	0.583333333333333	2.23351479046836	0.0181711375088439	0.0682841321201286
GO:0004126	cytidine deaminase activity	7/4868	12/18639	0.583333333333333	2.23351479046836	0.0181711375088439	0.0682841321201286
GO:0004300	enoyl-CoA hydratase activity	7/4868	12/18639	0.583333333333333	2.23351479046836	0.0181711375088439	0.0682841321201286
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	7/4868	12/18639	0.583333333333333	2.23351479046836	0.0181711375088439	0.0682841321201286
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	7/4868	12/18639	0.583333333333333	2.23351479046836	0.0181711375088439	0.0682841321201286
GO:1990247	N6-methyladenosine-containing RNA reader activity	7/4868	12/18639	0.583333333333333	2.23351479046836	0.0181711375088439	0.0682841321201286
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	10/4868	20/18639	0.5	1.91444124897288	0.018838372894871	0.0701915645433187
GO:0016505	peptidase activator activity involved in apoptotic process	10/4868	20/18639	0.5	1.91444124897288	0.018838372894871	0.0701915645433187
GO:0140664	ATP-dependent DNA damage sensor activity	10/4868	20/18639	0.5	1.91444124897288	0.018838372894871	0.0701915645433187
GO:0004860	protein kinase inhibitor activity	31/4868	84/18639	0.369047619047619	1.41303996947999	0.0189885892547936	0.0705519696537259
GO:0033192	calmodulin-dependent protein phosphatase activity	30/4868	81/18639	0.37037037037037	1.4181046288688	0.0197304473331407	0.0716927273620181
GO:0140791	histone H2AXS140 phosphatase activity	30/4868	81/18639	0.37037037037037	1.4181046288688	0.0197304473331407	0.0716927273620181
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	30/4868	81/18639	0.37037037037037	1.4181046288688	0.0197304473331407	0.0716927273620181
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	30/4868	81/18639	0.37037037037037	1.4181046288688	0.0197304473331407	0.0716927273620181
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	30/4868	81/18639	0.37037037037037	1.4181046288688	0.0197304473331407	0.0716927273620181
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	30/4868	81/18639	0.37037037037037	1.4181046288688	0.0197304473331407	0.0716927273620181
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	30/4868	81/18639	0.37037037037037	1.4181046288688	0.0197304473331407	0.0716927273620181
GO:1990439	MAP kinase serine/threonine phosphatase activity	30/4868	81/18639	0.37037037037037	1.4181046288688	0.0197304473331407	0.0716927273620181
GO:0019208	phosphatase regulator activity	41/4868	117/18639	0.35042735042735	1.34174514885279	0.0200878254437122	0.0727907740666384
GO:0140102	catalytic activity, acting on a rRNA	11/4868	23/18639	0.478260869565217	1.83120467293059	0.0205263986826985	0.0741456533475058
GO:0036002	pre-mRNA binding	23/4868	59/18639	0.389830508474576	1.4926152110636	0.0205741539993837	0.0741456533475058
GO:0051018	protein kinase A binding	21/4868	53/18639	0.39622641509434	1.51710438597851	0.0216464098473753	0.0776424779351412
GO:0016289	acyl-CoA hydrolase activity	12/4868	26/18639	0.461538461538462	1.76717653751343	0.0217210571327271	0.0776424779351412
GO:0034237	protein kinase A regulatory subunit binding	12/4868	26/18639	0.461538461538462	1.76717653751343	0.0217210571327271	0.0776424779351412
GO:0000774	adenyl-nucleotide exchange factor activity	8/4868	15/18639	0.533333333333333	2.04207066557108	0.0224505182059814	0.0793893659884435
GO:0050700	CARD domain binding	8/4868	15/18639	0.533333333333333	2.04207066557108	0.0224505182059814	0.0793893659884435
GO:0141050	histone H3K deacetylase activity	8/4868	15/18639	0.533333333333333	2.04207066557108	0.0224505182059814	0.0793893659884435
GO:0141051	histone H4K deacetylase activity	8/4868	15/18639	0.533333333333333	2.04207066557108	0.0224505182059814	0.0793893659884435
GO:0016877	ligase activity, forming carbon-sulfur bonds	17/4868	41/18639	0.414634146341463	1.58758542597751	0.0231387002623439	0.0816041327434002
GO:0033549	MAP kinase phosphatase activity	30/4868	82/18639	0.365853658536585	1.40081066998016	0.0235221130161104	0.082735112181999
GO:0016783	sulfurtransferase activity	6/4868	10/18639	0.6	2.29732949876746	0.0244131355024181	0.0845168654270066
GO:0030957	Tat protein binding	6/4868	10/18639	0.6	2.29732949876746	0.0244131355024181	0.0845168654270066
GO:0031996	thioesterase binding	6/4868	10/18639	0.6	2.29732949876746	0.0244131355024181	0.0845168654270066
GO:0043422	protein kinase B binding	6/4868	10/18639	0.6	2.29732949876746	0.0244131355024181	0.0845168654270066
GO:0051864	histone H3K36 demethylase activity	6/4868	10/18639	0.6	2.29732949876746	0.0244131355024181	0.0845168654270066
GO:0099122	RNA polymerase II C-terminal domain binding	6/4868	10/18639	0.6	2.29732949876746	0.0244131355024181	0.0845168654270066
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	23/4868	60/18639	0.383333333333333	1.46773829087921	0.0253122815695069	0.0874002601837161
GO:0000900	mRNA regulatory element binding translation repressor activity	9/4868	18/18639	0.5	1.91444124897288	0.0255455023449867	0.0877461395652018
GO:0008409	5'-3' exonuclease activity	9/4868	18/18639	0.5	1.91444124897288	0.0255455023449867	0.0877461395652018
GO:0030295	protein kinase activator activity	47/4868	139/18639	0.338129496402878	1.29465811081619	0.0262733551458286	0.0900118323047999
GO:0005048	signal sequence binding	20/4868	51/18639	0.392156862745098	1.50152254821403	0.027675703659955	0.0944150403728552
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	10/4868	21/18639	0.476190476190476	1.82327737997418	0.0277017593815731	0.0944150403728552
GO:0000149	SNARE binding	37/4868	106/18639	0.349056603773585	1.33649672098107	0.0278313783738777	0.0946123403998575
GO:0140303	intramembrane lipid transporter activity	18/4868	45/18639	0.4	1.53155299917831	0.0290592798463825	0.0985326224097134
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	73/4868	229/18639	0.318777292576419	1.22056079628839	0.0291732311223531	0.0986653637189325
GO:0048487	beta-tubulin binding	17/4868	42/18639	0.404761904761905	1.54978577297805	0.029639603124479	0.0999862826628845
GO:0008266	poly(U) RNA binding	12/4868	27/18639	0.444444444444444	1.70172555464256	0.0300046597596782	0.100702662145078
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	12/4868	27/18639	0.444444444444444	1.70172555464256	0.0300046597596782	0.100702662145078
GO:0008187	poly-pyrimidine tract binding	13/4868	30/18639	0.433333333333333	1.6591824157765	0.0304500199182321	0.10145457611001
GO:0140311	protein sequestering activity	14/4868	33/18639	0.424242424242424	1.6243743930679	0.0305678374031483	0.10145457611001
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	7/4868	13/18639	0.538461538461538	2.06170596043234	0.0306132837693587	0.10145457611001
GO:0043560	insulin receptor substrate binding	7/4868	13/18639	0.538461538461538	2.06170596043234	0.0306132837693587	0.10145457611001
GO:0097157	pre-mRNA intronic binding	7/4868	13/18639	0.538461538461538	2.06170596043234	0.0306132837693587	0.10145457611001
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	23/4868	61/18639	0.377049180327869	1.44367700742217	0.0308425869268348	0.101958326206755
GO:0004519	endonuclease activity	43/4868	127/18639	0.338582677165354	1.29639328670605	0.0316940397405521	0.10451109604447
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	22/4868	58/18639	0.379310344827586	1.45233474060012	0.0319666467746828	0.105147149864854
GO:0019888	protein phosphatase regulator activity	37/4868	107/18639	0.345794392523364	1.3240060974205	0.0321091632132988	0.105353199697366
GO:0017018	myosin phosphatase activity	30/4868	84/18639	0.357142857142857	1.36745803498063	0.0327870774905313	0.107310558833774
GO:0004708	MAP kinase kinase activity	8/4868	16/18639	0.5	1.91444124897288	0.0348022979865456	0.111689126628355
GO:0008296	3'-5'-DNA exonuclease activity	8/4868	16/18639	0.5	1.91444124897288	0.0348022979865456	0.111689126628355
GO:0017070	U6 snRNA binding	8/4868	16/18639	0.5	1.91444124897288	0.0348022979865456	0.111689126628355
GO:0030275	LRR domain binding	8/4868	16/18639	0.5	1.91444124897288	0.0348022979865456	0.111689126628355
GO:0034450	ubiquitin-ubiquitin ligase activity	8/4868	16/18639	0.5	1.91444124897288	0.0348022979865456	0.111689126628355
GO:0097027	ubiquitin-protein transferase activator activity	8/4868	16/18639	0.5	1.91444124897288	0.0348022979865456	0.111689126628355
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	8/4868	16/18639	0.5	1.91444124897288	0.0348022979865456	0.111689126628355
GO:0140328	floppase activity	8/4868	16/18639	0.5	1.91444124897288	0.0348022979865456	0.111689126628355
GO:0031490	chromatin DNA binding	43/4868	128/18639	0.3359375	1.28626521415366	0.035976762824306	0.115178034381698
GO:0048156	tau protein binding	17/4868	43/18639	0.395348837209302	1.51374424337391	0.0374017716529061	0.119450210194148
GO:0046527	glucosyltransferase activity	9/4868	19/18639	0.473684210526316	1.81368118323747	0.037518156008217	0.119532482547919
GO:0030331	nuclear estrogen receptor binding	16/4868	40/18639	0.4	1.53155299917831	0.0383328107410486	0.121540810979431
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	16/4868	40/18639	0.4	1.53155299917831	0.0383328107410486	0.121540810979431
GO:0031593	polyubiquitin modification-dependent protein binding	22/4868	59/18639	0.372881355932203	1.4277188975391	0.0387405613978336	0.122539089889071
GO:0050321	tau-protein kinase activity	10/4868	22/18639	0.454545454545455	1.74040113542989	0.0391654153381628	0.123586561796739
GO:0030332	cyclin binding	14/4868	34/18639	0.411764705882353	1.57659867562473	0.0397954229563989	0.125274851741026
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	11/4868	25/18639	0.44	1.68470829909614	0.0400351512667416	0.125729439335315
GO:0005164	tumor necrosis factor receptor binding	13/4868	31/18639	0.419354838709677	1.60566040236435	0.0402193761939369	0.125776256506743
GO:0016866	intramolecular transferase activity	12/4868	28/18639	0.428571428571429	1.64094964197676	0.040336130782678	0.125776256506743
GO:0019789	SUMO transferase activity	12/4868	28/18639	0.428571428571429	1.64094964197676	0.040336130782678	0.125776256506743
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	6/4868	11/18639	0.545454545454545	2.08848136251587	0.0420049361919587	0.12884769962138
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	6/4868	11/18639	0.545454545454545	2.08848136251587	0.0420049361919587	0.12884769962138
GO:0019107	myristoyltransferase activity	6/4868	11/18639	0.545454545454545	2.08848136251587	0.0420049361919587	0.12884769962138
GO:0042608	T cell receptor binding	6/4868	11/18639	0.545454545454545	2.08848136251587	0.0420049361919587	0.12884769962138
GO:0140031	phosphorylation-dependent protein binding	6/4868	11/18639	0.545454545454545	2.08848136251587	0.0420049361919587	0.12884769962138
GO:0140537	transcription regulator activator activity	6/4868	11/18639	0.545454545454545	2.08848136251587	0.0420049361919587	0.12884769962138
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	6/4868	11/18639	0.545454545454545	2.08848136251587	0.0420049361919587	0.12884769962138
GO:0016874	ligase activity	54/4868	167/18639	0.323353293413174	1.23808176580282	0.0423408671403116	0.129576806863274
GO:0032813	tumor necrosis factor receptor superfamily binding	19/4868	50/18639	0.38	1.45497534921939	0.0434070947348888	0.132532310081755
GO:0001784	phosphotyrosine residue binding	18/4868	47/18639	0.382978723404255	1.46638053112817	0.0449811874308837	0.137021215291768
GO:0008174	mRNA methyltransferase activity	7/4868	14/18639	0.5	1.91444124897288	0.0476897196469171	0.143613562133068
GO:0034236	protein kinase A catalytic subunit binding	7/4868	14/18639	0.5	1.91444124897288	0.0476897196469171	0.143613562133068
GO:0046030	inositol trisphosphate phosphatase activity	7/4868	14/18639	0.5	1.91444124897288	0.0476897196469171	0.143613562133068
GO:0070742	C2H2 zinc finger domain binding	7/4868	14/18639	0.5	1.91444124897288	0.0476897196469171	0.143613562133068
GO:1990825	sequence-specific mRNA binding	7/4868	14/18639	0.5	1.91444124897288	0.0476897196469171	0.143613562133068
GO:0016504	peptidase activator activity	21/4868	57/18639	0.368421052631579	1.41064092029581	0.0485323361156626	0.145818112383961
GO:0043531	ADP binding	15/4868	38/18639	0.394736842105263	1.51140098603122	0.0495040113667448	0.148399524983492
GO:0003925	G protein activity	20/4868	54/18639	0.37037037037037	1.4181046288688	0.0506117778128467	0.151256703765151
GO:0005092	GDP-dissociation inhibitor activity	8/4868	17/18639	0.470588235294118	1.80182705785683	0.0510305027865748	0.151256703765151
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	8/4868	17/18639	0.470588235294118	1.80182705785683	0.0510305027865748	0.151256703765151
GO:0031489	myosin V binding	8/4868	17/18639	0.470588235294118	1.80182705785683	0.0510305027865748	0.151256703765151
GO:0032977	membrane insertase activity	8/4868	17/18639	0.470588235294118	1.80182705785683	0.0510305027865748	0.151256703765151
GO:0008378	galactosyltransferase activity	13/4868	32/18639	0.40625	1.55548351479047	0.0520000949075991	0.153785034042877
GO:0030742	GTP-dependent protein binding	9/4868	20/18639	0.45	1.7229971240756	0.0528016149191366	0.155438419234389
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	12/4868	29/18639	0.413793103448276	1.58436517156377	0.0529126991935107	0.155438419234389
GO:0097472	cyclin-dependent protein kinase activity	12/4868	29/18639	0.413793103448276	1.58436517156377	0.0529126991935107	0.155438419234389
GO:0008143	poly(A) binding	11/4868	26/18639	0.423076923076923	1.61991182605398	0.053465486965019	0.15612968115879
GO:0003887	DNA-directed DNA polymerase activity	10/4868	23/18639	0.434782608695652	1.66473152084599	0.0535031204577507	0.15612968115879
GO:0043274	phospholipase binding	10/4868	23/18639	0.434782608695652	1.66473152084599	0.0535031204577507	0.15612968115879
GO:0035401	histone H3Y41 kinase activity	38/4868	115/18639	0.330434782608696	1.26519595584295	0.0584722829579232	0.169878725157491
GO:0140801	histone H2AXY142 kinase activity	38/4868	115/18639	0.330434782608696	1.26519595584295	0.0584722829579232	0.169878725157491
GO:0016859	cis-trans isomerase activity	16/4868	42/18639	0.380952380952381	1.45862190397934	0.0593908496461521	0.1721681993039
GO:0140313	molecular sequestering activity	20/4868	55/18639	0.363636363636364	1.39232090834392	0.0606217219558573	0.175350989604771
GO:0000217	DNA secondary structure binding	15/4868	39/18639	0.384615384615385	1.47264711459453	0.0616252286922893	0.17747527651775
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	15/4868	39/18639	0.384615384615385	1.47264711459453	0.0616252286922893	0.17747527651775
GO:0004713	protein tyrosine kinase activity	45/4868	140/18639	0.321428571428571	1.23071223148257	0.0649086750413025	0.18652405747163
GO:0035197	siRNA binding	6/4868	12/18639	0.5	1.91444124897288	0.0658387348750736	0.188375903037358
GO:0141221	histone deacetylase activity, hydrolytic mechanism	6/4868	12/18639	0.5	1.91444124897288	0.0658387348750736	0.188375903037358
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	42/4868	130/18639	0.323076923076923	1.2370235762594	0.06749674778283	0.192701753951413
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	7/4868	15/18639	0.466666666666667	1.78681183237469	0.0697740209077359	0.198344684433844
GO:0055105	ubiquitin-protein transferase inhibitor activity	7/4868	15/18639	0.466666666666667	1.78681183237469	0.0697740209077359	0.198344684433844
GO:0140033	acetylation-dependent protein binding	10/4868	24/18639	0.416666666666667	1.5953677074774	0.0709111004665439	0.201011408869949
GO:0003746	translation elongation factor activity	8/4868	18/18639	0.444444444444444	1.70172555464256	0.0714185031398454	0.201011408869949
GO:0070628	proteasome binding	8/4868	18/18639	0.444444444444444	1.70172555464256	0.0714185031398454	0.201011408869949
GO:1990381	ubiquitin-specific protease binding	8/4868	18/18639	0.444444444444444	1.70172555464256	0.0714185031398454	0.201011408869949
GO:0009931	calcium-dependent protein serine/threonine kinase activity	9/4868	21/18639	0.428571428571429	1.64094964197676	0.0716265065723093	0.201011408869949
GO:0070182	DNA polymerase binding	9/4868	21/18639	0.428571428571429	1.64094964197676	0.0716265065723093	0.201011408869949
GO:0051213	dioxygenase activity	31/4868	93/18639	0.333333333333333	1.27629416598192	0.073315676866631	0.205315027148803
GO:0015605	organophosphate ester transmembrane transporter activity	18/4868	50/18639	0.36	1.37839769926048	0.0792072606185672	0.221344018550615
GO:0016831	carboxy-lyase activity	13/4868	34/18639	0.382352941176471	1.46398448450868	0.0821102675844549	0.228555664738287
GO:0022853	active monoatomic ion transmembrane transporter activity	38/4868	118/18639	0.322033898305085	1.23302995696559	0.0821344845230841	0.228555664738287
GO:0008327	methyl-CpG binding	12/4868	31/18639	0.387096774193548	1.48214806372094	0.0853626245102112	0.237038529955723
GO:0004725	protein tyrosine phosphatase activity	32/4868	98/18639	0.326530612244898	1.25024734626801	0.0887702248227848	0.244622947060034
GO:0051287	NAD binding	19/4868	54/18639	0.351851851851852	1.34719939742536	0.088977381421395	0.244622947060034
GO:0004709	MAP kinase kinase kinase activity	10/4868	25/18639	0.4	1.53155299917831	0.0914950665997453	0.244622947060034
GO:0005131	growth hormone receptor binding	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0016303	1-phosphatidylinositol-3-kinase activity	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0016427	tRNA (cytidine) methyltransferase activity	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0033204	ribonuclease P RNA binding	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0042975	peroxisome proliferator activated receptor binding	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0045322	unmethylated CpG binding	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0047429	nucleoside triphosphate diphosphatase activity	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0050815	phosphoserine residue binding	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0070513	death domain binding	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0097177	mitochondrial ribosome binding	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:1990757	ubiquitin ligase activator activity	5/4868	10/18639	0.5	1.91444124897288	0.0918031529906873	0.244622947060034
GO:0005338	nucleotide-sugar transmembrane transporter activity	6/4868	13/18639	0.461538461538462	1.76717653751343	0.0960319786799722	0.253949266713236
GO:0046974	histone H3K9 methyltransferase activity	6/4868	13/18639	0.461538461538462	1.76717653751343	0.0960319786799722	0.253949266713236
GO:0003756	protein disulfide isomerase activity	8/4868	19/18639	0.421052631578947	1.61216105176664	0.0960733010537566	0.253949266713236
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	8/4868	19/18639	0.421052631578947	1.61216105176664	0.0960733010537566	0.253949266713236
GO:0005521	lamin binding	7/4868	16/18639	0.4375	1.67513609285127	0.0969742498464394	0.254156986447576
GO:0022858	alanine transmembrane transporter activity	7/4868	16/18639	0.4375	1.67513609285127	0.0969742498464394	0.254156986447576
GO:0070411	I-SMAD binding	7/4868	16/18639	0.4375	1.67513609285127	0.0969742498464394	0.254156986447576
GO:0140327	flippase activity	7/4868	16/18639	0.4375	1.67513609285127	0.0969742498464394	0.254156986447576
GO:0005548	phospholipid transporter activity	23/4868	68/18639	0.338235294117647	1.2950631978346	0.0971153306820155	0.254156986447576
GO:0034061	DNA polymerase activity	13/4868	35/18639	0.371428571428571	1.42215635637986	0.100589607149247	0.26272810263338
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	29/4868	89/18639	0.325842696629214	1.24761339820705	0.103573067401395	0.269453404146824
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	29/4868	89/18639	0.325842696629214	1.24761339820705	0.103573067401395	0.269453404146824
GO:0004520	DNA endonuclease activity	15/4868	42/18639	0.357142857142857	1.36745803498063	0.109324789973604	0.283857082628314
GO:0035250	UDP-galactosyltransferase activity	11/4868	29/18639	0.379310344827586	1.45233474060012	0.110291116778156	0.285803503006657
GO:0001217	DNA-binding transcription repressor activity	82/4868	278/18639	0.294964028776978	1.12938260730774	0.111470555913774	0.288293457353468
GO:0140793	histone H2AXY142 phosphatase activity	29/4868	90/18639	0.322222222222222	1.23375102711586	0.116146450167787	0.299798762761862
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	79/4868	268/18639	0.294776119402985	1.12866312439446	0.117548640028978	0.302825500387152
GO:0070577	lysine-acetylated histone binding	9/4868	23/18639	0.391304347826087	1.49825836876139	0.120197287126549	0.309045266510562
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	13/4868	36/18639	0.361111111111111	1.38265201314708	0.121371803097456	0.310250791251056
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	13/4868	36/18639	0.361111111111111	1.38265201314708	0.121371803097456	0.310250791251056
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	13/4868	36/18639	0.361111111111111	1.38265201314708	0.121371803097456	0.310250791251056
GO:0030291	protein serine/threonine kinase inhibitor activity	16/4868	46/18639	0.347826086956522	1.33178521667679	0.122181582334133	0.311716648160003
GO:0016004	phospholipase activator activity	8/4868	20/18639	0.4	1.53155299917831	0.12492109181017	0.318090579339024
GO:0140416	transcription regulator inhibitor activity	12/4868	33/18639	0.363636363636364	1.39232090834392	0.127922473692514	0.325105477457468
GO:0051117	ATPase binding	27/4868	84/18639	0.321428571428571	1.23071223148257	0.129006527575768	0.325676667701389
GO:0004550	nucleoside diphosphate kinase activity	7/4868	17/18639	0.411764705882353	1.57659867562473	0.129134872788344	0.325676667701389
GO:0070402	NADPH binding	7/4868	17/18639	0.411764705882353	1.57659867562473	0.129134872788344	0.325676667701389
GO:0070403	NAD+ binding	7/4868	17/18639	0.411764705882353	1.57659867562473	0.129134872788344	0.325676667701389
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	6/4868	14/18639	0.428571428571429	1.64094964197676	0.132288672954763	0.331120336646551
GO:0061665	SUMO ligase activity	6/4868	14/18639	0.428571428571429	1.64094964197676	0.132288672954763	0.331120336646551
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	5/4868	11/18639	0.454545454545455	1.74040113542989	0.133301666989628	0.331120336646551
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	5/4868	11/18639	0.454545454545455	1.74040113542989	0.133301666989628	0.331120336646551
GO:0004143	ATP-dependent diacylglycerol kinase activity	5/4868	11/18639	0.454545454545455	1.74040113542989	0.133301666989628	0.331120336646551
GO:0015173	aromatic amino acid transmembrane transporter activity	5/4868	11/18639	0.454545454545455	1.74040113542989	0.133301666989628	0.331120336646551
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	5/4868	11/18639	0.454545454545455	1.74040113542989	0.133301666989628	0.331120336646551
GO:0180030	inositol phosphate kinase activity	5/4868	11/18639	0.454545454545455	1.74040113542989	0.133301666989628	0.331120336646551
GO:0051721	protein phosphatase 2A binding	11/4868	30/18639	0.366666666666667	1.40392358258011	0.134840394606879	0.33431293324525
GO:0004683	calcium/calmodulin-dependent protein kinase activity	10/4868	27/18639	0.37037037037037	1.4181046288688	0.142127523402484	0.351718955662058
GO:0035035	histone acetyltransferase binding	9/4868	24/18639	0.375	1.43583093672966	0.149768999122553	0.36924356979934
GO:0060229	lipase activator activity	9/4868	24/18639	0.375	1.43583093672966	0.149768999122553	0.36924356979934
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	12/4868	34/18639	0.352941176470588	1.35137029339262	0.152910949751455	0.376286460302555
GO:0005123	death receptor binding	8/4868	21/18639	0.380952380952381	1.45862190397934	0.157717759648853	0.385954962851275
GO:0051010	microtubule plus-end binding	8/4868	21/18639	0.380952380952381	1.45862190397934	0.157717759648853	0.385954962851275
GO:1904047	S-adenosyl-L-methionine binding	8/4868	21/18639	0.380952380952381	1.45862190397934	0.157717759648853	0.385954962851275
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	14/4868	41/18639	0.341463414634146	1.30742329198148	0.159820116056694	0.39037543162737
GO:0016835	carbon-oxygen lyase activity	25/4868	79/18639	0.316455696202532	1.21167167656512	0.160227844346183	0.390647923646239
GO:0004706	JUN kinase kinase kinase activity	7/4868	18/18639	0.388888888888889	1.48900986031224	0.165863471655571	0.40289856190368
GO:0008525	phosphatidylcholine transporter activity	7/4868	18/18639	0.388888888888889	1.48900986031224	0.165863471655571	0.40289856190368
GO:0016757	glycosyltransferase activity	77/4868	267/18639	0.288389513108614	1.10420955933267	0.170862707539424	0.414279248611213
GO:0008252	nucleotidase activity	6/4868	15/18639	0.4	1.53155299917831	0.173965107652782	0.420256368120914
GO:0048531	beta-1,3-galactosyltransferase activity	6/4868	15/18639	0.4	1.53155299917831	0.173965107652782	0.420256368120914
GO:0004521	RNA endonuclease activity	23/4868	73/18639	0.315068493150685	1.2063602390788	0.178639004482418	0.430758403861626
GO:0015399	primary active transmembrane transporter activity	49/4868	166/18639	0.295180722891566	1.1302123036105	0.179928129333573	0.432961249173806
GO:0005154	epidermal growth factor receptor binding	12/4868	35/18639	0.342857142857143	1.31275971358141	0.180209041543912	0.432961249173806
GO:0004526	ribonuclease P activity	5/4868	12/18639	0.416666666666667	1.5953677074774	0.18148947564288	0.433667786907535
GO:0097677	STAT family protein binding	5/4868	12/18639	0.416666666666667	1.5953677074774	0.18148947564288	0.433667786907535
GO:1990459	transferrin receptor binding	5/4868	12/18639	0.416666666666667	1.5953677074774	0.18148947564288	0.433667786907535
GO:0031492	nucleosomal DNA binding	14/4868	42/18639	0.333333333333333	1.27629416598192	0.18506777909824	0.44141844598658
GO:0016417	S-acyltransferase activity	10/4868	29/18639	0.344827586206897	1.32030430963647	0.204334356875423	0.486492809961522
GO:0008301	DNA binding, bending	7/4868	19/18639	0.368421052631579	1.41064092029581	0.20657440450663	0.489177090743706
GO:0046624	sphingolipid transporter activity	7/4868	19/18639	0.368421052631579	1.41064092029581	0.20657440450663	0.489177090743706
GO:0050145	nucleoside monophosphate kinase activity	7/4868	19/18639	0.368421052631579	1.41064092029581	0.20657440450663	0.489177090743706
GO:0140299	molecular sensor activity	22/4868	71/18639	0.309859154929577	1.18641429513813	0.209539095377411	0.495308363445886
GO:0097602	cullin family protein binding	9/4868	26/18639	0.346153846153846	1.32538240313507	0.218169309146434	0.514785901188098
GO:0050660	flavin adenine dinucleotide binding	26/4868	86/18639	0.302325581395349	1.15756912728593	0.224759225468017	0.529388247129133
GO:0042171	lysophosphatidic acid acyltransferase activity	8/4868	23/18639	0.347826086956522	1.33178521667679	0.233470330442927	0.546443813812623
GO:0071617	lysophospholipid acyltransferase activity	8/4868	23/18639	0.347826086956522	1.33178521667679	0.233470330442927	0.546443813812623
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	5/4868	13/18639	0.384615384615385	1.47264711459453	0.234900411244698	0.546443813812623
GO:0005035	death receptor activity	5/4868	13/18639	0.384615384615385	1.47264711459453	0.234900411244698	0.546443813812623
GO:0008253	5'-nucleotidase activity	5/4868	13/18639	0.384615384615385	1.47264711459453	0.234900411244698	0.546443813812623
GO:0035673	oligopeptide transmembrane transporter activity	5/4868	13/18639	0.384615384615385	1.47264711459453	0.234900411244698	0.546443813812623
GO:0140333	glycerophospholipid flippase activity	5/4868	13/18639	0.384615384615385	1.47264711459453	0.234900411244698	0.546443813812623
GO:0061980	regulatory RNA binding	18/4868	58/18639	0.310344827586207	1.18827387867282	0.237043008897011	0.550457268899926
GO:0015078	proton transmembrane transporter activity	53/4868	185/18639	0.286486486486487	1.09692309400609	0.238806040712616	0.552605557368317
GO:1901981	phosphatidylinositol phosphate binding	53/4868	185/18639	0.286486486486487	1.09692309400609	0.238806040712616	0.552605557368317
GO:0001223	transcription coactivator binding	14/4868	44/18639	0.318181818181818	1.21828079480093	0.240710643082605	0.556037369922864
GO:0016408	C-acyltransferase activity	7/4868	20/18639	0.35	1.34010887428102	0.250541572881647	0.565346934104419
GO:0042288	MHC class I protein binding	7/4868	20/18639	0.35	1.34010887428102	0.250541572881647	0.565346934104419
GO:0001094	TFIID-class transcription factor complex binding	4/4868	10/18639	0.4	1.53155299917831	0.250741437794606	0.565346934104419
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	4/4868	10/18639	0.4	1.53155299917831	0.250741437794606	0.565346934104419
GO:0004445	inositol-polyphosphate 5-phosphatase activity	4/4868	10/18639	0.4	1.53155299917831	0.250741437794606	0.565346934104419
GO:0004955	prostaglandin receptor activity	4/4868	10/18639	0.4	1.53155299917831	0.250741437794606	0.565346934104419
GO:0005522	profilin binding	4/4868	10/18639	0.4	1.53155299917831	0.250741437794606	0.565346934104419
GO:0005528	FK506 binding	4/4868	10/18639	0.4	1.53155299917831	0.250741437794606	0.565346934104419
GO:0008140	cAMP response element binding protein binding	4/4868	10/18639	0.4	1.53155299917831	0.250741437794606	0.565346934104419
GO:0015279	store-operated calcium channel activity	4/4868	10/18639	0.4	1.53155299917831	0.250741437794606	0.565346934104419
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	4/4868	10/18639	0.4	1.53155299917831	0.250741437794606	0.565346934104419
GO:0051880	G-quadruplex DNA binding	4/4868	10/18639	0.4	1.53155299917831	0.250741437794606	0.565346934104419
GO:0140940	histone H2A methyltransferase activity	4/4868	10/18639	0.4	1.53155299917831	0.250741437794606	0.565346934104419
GO:1990259	histone H2AQ104 methyltransferase activity	4/4868	10/18639	0.4	1.53155299917831	0.250741437794606	0.565346934104419
GO:0016651	oxidoreductase activity, acting on NAD(P)H	26/4868	88/18639	0.295454545454545	1.13126073802943	0.266335047595732	0.599481105424522
GO:0030159	signaling receptor complex adaptor activity	16/4868	52/18639	0.307692307692308	1.17811769167562	0.266948919747648	0.599839225122909
GO:0004549	tRNA-specific ribonuclease activity	6/4868	17/18639	0.352941176470588	1.35137029339262	0.269809485726538	0.60216364073317
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	6/4868	17/18639	0.352941176470588	1.35137029339262	0.269809485726538	0.60216364073317
GO:0017110	nucleoside diphosphate phosphatase activity	6/4868	17/18639	0.352941176470588	1.35137029339262	0.269809485726538	0.60216364073317
GO:1990226	histone methyltransferase binding	6/4868	17/18639	0.352941176470588	1.35137029339262	0.269809485726538	0.60216364073317
GO:0042887	amide transmembrane transporter activity	12/4868	38/18639	0.315789473684211	1.20912078882498	0.27385199250331	0.609261828335921
GO:0004622	lysophospholipase activity	8/4868	24/18639	0.333333333333333	1.27629416598192	0.275320996103115	0.609261828335921
GO:0070840	dynein complex binding	8/4868	24/18639	0.333333333333333	1.27629416598192	0.275320996103115	0.609261828335921
GO:0035091	phosphatidylinositol binding	79/4868	284/18639	0.278169014084507	1.065076469499	0.275665478157831	0.609261828335921
GO:0016878	acid-thiol ligase activity	10/4868	31/18639	0.32258064516129	1.23512338643412	0.275761418890481	0.609261828335921
GO:0070273	phosphatidylinositol-4-phosphate binding	10/4868	31/18639	0.32258064516129	1.23512338643412	0.275761418890481	0.609261828335921
GO:0035198	miRNA binding	13/4868	42/18639	0.30952380952381	1.18513029698321	0.288573603833196	0.636502647919709
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	5/4868	14/18639	0.357142857142857	1.36745803498063	0.291906932516884	0.640641004974659
GO:0044548	S100 protein binding	5/4868	14/18639	0.357142857142857	1.36745803498063	0.291906932516884	0.640641004974659
GO:0071933	Arp2/3 complex binding	5/4868	14/18639	0.357142857142857	1.36745803498063	0.291906932516884	0.640641004974659
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	7/4868	21/18639	0.333333333333333	1.27629416598192	0.296953479498044	0.646339339039471
GO:0009975	cyclase activity	7/4868	21/18639	0.333333333333333	1.27629416598192	0.296953479498044	0.646339339039471
GO:0035613	RNA stem-loop binding	7/4868	21/18639	0.333333333333333	1.27629416598192	0.296953479498044	0.646339339039471
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	7/4868	21/18639	0.333333333333333	1.27629416598192	0.296953479498044	0.646339339039471
GO:0072542	protein phosphatase activator activity	7/4868	21/18639	0.333333333333333	1.27629416598192	0.296953479498044	0.646339339039471
GO:0015932	nucleobase-containing compound transmembrane transporter activity	17/4868	57/18639	0.298245614035088	1.14194741166804	0.306799657420837	0.666670095779381
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	12/4868	39/18639	0.307692307692308	1.17811769167562	0.308087997671278	0.668368534421736
GO:0046332	SMAD binding	23/4868	79/18639	0.291139240506329	1.11473794243991	0.310454365995847	0.672396237682302
GO:0043425	bHLH transcription factor binding	10/4868	32/18639	0.3125	1.19652578060805	0.313953409811871	0.676199982931949
GO:0016836	hydro-lyase activity	18/4868	61/18639	0.295081967213115	1.1298341797217	0.317124529639796	0.676199982931949
GO:0019905	syntaxin binding	18/4868	61/18639	0.295081967213115	1.1298341797217	0.317124529639796	0.676199982931949
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	4/4868	11/18639	0.363636363636364	1.39232090834392	0.317849878254593	0.676199982931949
GO:0004954	prostanoid receptor activity	4/4868	11/18639	0.363636363636364	1.39232090834392	0.317849878254593	0.676199982931949
GO:0005225	volume-sensitive anion channel activity	4/4868	11/18639	0.363636363636364	1.39232090834392	0.317849878254593	0.676199982931949
GO:0019206	nucleoside kinase activity	4/4868	11/18639	0.363636363636364	1.39232090834392	0.317849878254593	0.676199982931949
GO:0032794	GTPase activating protein binding	4/4868	11/18639	0.363636363636364	1.39232090834392	0.317849878254593	0.676199982931949
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	4/4868	11/18639	0.363636363636364	1.39232090834392	0.317849878254593	0.676199982931949
GO:0043522	leucine zipper domain binding	4/4868	11/18639	0.363636363636364	1.39232090834392	0.317849878254593	0.676199982931949
GO:1990948	ubiquitin ligase inhibitor activity	4/4868	11/18639	0.363636363636364	1.39232090834392	0.317849878254593	0.676199982931949
GO:0019211	phosphatase activator activity	8/4868	25/18639	0.32	1.22524239934265	0.318978836073224	0.676419750451098
GO:0042974	nuclear retinoic acid receptor binding	8/4868	25/18639	0.32	1.22524239934265	0.318978836073224	0.676419750451098
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	13/4868	43/18639	0.302325581395349	1.15756912728593	0.321716765930311	0.67800496478132
GO:0008308	voltage-gated monoatomic anion channel activity	6/4868	18/18639	0.333333333333333	1.27629416598192	0.321782492762021	0.67800496478132
GO:0017128	phospholipid scramblase activity	6/4868	18/18639	0.333333333333333	1.27629416598192	0.321782492762021	0.67800496478132
GO:0050811	GABA receptor binding	6/4868	18/18639	0.333333333333333	1.27629416598192	0.321782492762021	0.67800496478132
GO:0050661	NADP binding	16/4868	54/18639	0.296296296296296	1.13448370309504	0.32534388021406	0.684415594900073
GO:0120013	lipid transfer activity	19/4868	65/18639	0.292307692307692	1.11921180709184	0.326775018133961	0.686331606558432
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	12/4868	40/18639	0.3	1.14866474938373	0.343324262160743	0.71994388201911
GO:0061133	endopeptidase activator activity	7/4868	22/18639	0.318181818181818	1.21828079480093	0.344965298117147	0.722236870184947
GO:0004953	icosanoid receptor activity	5/4868	15/18639	0.333333333333333	1.27629416598192	0.350877844948935	0.732290945391844
GO:0016846	carbon-sulfur lyase activity	5/4868	15/18639	0.333333333333333	1.27629416598192	0.350877844948935	0.732290945391844
GO:0097110	scaffold protein binding	20/4868	70/18639	0.285714285714286	1.09396642798451	0.362840165314074	0.749734171369964
GO:0005112	Notch binding	8/4868	26/18639	0.307692307692308	1.17811769167562	0.363783070262909	0.749734171369964
GO:0008157	protein phosphatase 1 binding	8/4868	26/18639	0.307692307692308	1.17811769167562	0.363783070262909	0.749734171369964
GO:0030507	spectrin binding	8/4868	26/18639	0.307692307692308	1.17811769167562	0.363783070262909	0.749734171369964
GO:0043548	phosphatidylinositol 3-kinase binding	8/4868	26/18639	0.307692307692308	1.17811769167562	0.363783070262909	0.749734171369964
GO:0051139	metal cation:proton antiporter activity	8/4868	26/18639	0.307692307692308	1.17811769167562	0.363783070262909	0.749734171369964
GO:0070006	metalloaminopeptidase activity	8/4868	26/18639	0.307692307692308	1.17811769167562	0.363783070262909	0.749734171369964
GO:0120014	phospholipid transfer activity	8/4868	26/18639	0.307692307692308	1.17811769167562	0.363783070262909	0.749734171369964
GO:0042169	SH2 domain binding	12/4868	41/18639	0.292682926829268	1.12064853598413	0.379236610646569	0.777076699417704
GO:0015215	nucleotide transmembrane transporter activity	9/4868	30/18639	0.3	1.14866474938373	0.379558725354939	0.777076699417704
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	19/4868	67/18639	0.283582089552239	1.08580249941746	0.382441686750095	0.777076699417704
GO:0005078	MAP-kinase scaffold activity	4/4868	12/18639	0.333333333333333	1.27629416598192	0.38603007956045	0.777076699417704
GO:0005527	macrolide binding	4/4868	12/18639	0.333333333333333	1.27629416598192	0.38603007956045	0.777076699417704
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	4/4868	12/18639	0.333333333333333	1.27629416598192	0.38603007956045	0.777076699417704
GO:0008603	cAMP-dependent protein kinase regulator activity	4/4868	12/18639	0.333333333333333	1.27629416598192	0.38603007956045	0.777076699417704
GO:0016423	tRNA (guanine) methyltransferase activity	4/4868	12/18639	0.333333333333333	1.27629416598192	0.38603007956045	0.777076699417704
GO:0016840	carbon-nitrogen lyase activity	4/4868	12/18639	0.333333333333333	1.27629416598192	0.38603007956045	0.777076699417704
GO:0035014	phosphatidylinositol 3-kinase regulator activity	4/4868	12/18639	0.333333333333333	1.27629416598192	0.38603007956045	0.777076699417704
GO:0035251	UDP-glucosyltransferase activity	4/4868	12/18639	0.333333333333333	1.27629416598192	0.38603007956045	0.777076699417704
GO:0036009	protein-glutamine N-methyltransferase activity	4/4868	12/18639	0.333333333333333	1.27629416598192	0.38603007956045	0.777076699417704
GO:0042301	phosphate ion binding	4/4868	12/18639	0.333333333333333	1.27629416598192	0.38603007956045	0.777076699417704
GO:0097371	MDM2/MDM4 family protein binding	4/4868	12/18639	0.333333333333333	1.27629416598192	0.38603007956045	0.777076699417704
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	4/4868	12/18639	0.333333333333333	1.27629416598192	0.38603007956045	0.777076699417704
GO:0019212	phosphatase inhibitor activity	16/4868	56/18639	0.285714285714286	1.09396642798451	0.386476356950731	0.777076699417704
GO:0016849	phosphorus-oxygen lyase activity	7/4868	23/18639	0.304347826086957	1.16531206459219	0.393744346474618	0.789283879939242
GO:0140103	catalytic activity, acting on a glycoprotein	7/4868	23/18639	0.304347826086957	1.16531206459219	0.393744346474618	0.789283879939242
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	5/4868	16/18639	0.3125	1.19652578060805	0.410295218863639	0.815029207351115
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/4868	16/18639	0.3125	1.19652578060805	0.410295218863639	0.815029207351115
GO:0005324	long-chain fatty acid transmembrane transporter activity	5/4868	16/18639	0.3125	1.19652578060805	0.410295218863639	0.815029207351115
GO:0008142	oxysterol binding	5/4868	16/18639	0.3125	1.19652578060805	0.410295218863639	0.815029207351115
GO:0015562	efflux transmembrane transporter activity	5/4868	16/18639	0.3125	1.19652578060805	0.410295218863639	0.815029207351115
GO:0015923	mannosidase activity	5/4868	16/18639	0.3125	1.19652578060805	0.410295218863639	0.815029207351115
GO:0002020	protease binding	37/4868	136/18639	0.272058823529412	1.04168126782348	0.418076972716024	0.829238386484867
GO:0017022	myosin binding	21/4868	76/18639	0.276315789473684	1.05798069022186	0.424546690327975	0.840806433247146
GO:0052689	carboxylic ester hydrolase activity	25/4868	92/18639	0.271739130434783	1.04045720052874	0.447958103700186	0.885842187077279
GO:0002161	aminoacyl-tRNA editing activity	4/4868	13/18639	0.307692307692308	1.17811769167562	0.453198821034117	0.893526524579971
GO:0035325	Toll-like receptor binding	4/4868	13/18639	0.307692307692308	1.17811769167562	0.453198821034117	0.893526524579971
GO:0008429	phosphatidylethanolamine binding	5/4868	17/18639	0.294117647058824	1.12614191116052	0.468830941004098	0.918852914092727
GO:0016018	cyclosporin A binding	5/4868	17/18639	0.294117647058824	1.12614191116052	0.468830941004098	0.918852914092727
GO:0045125	bioactive lipid receptor activity	5/4868	17/18639	0.294117647058824	1.12614191116052	0.468830941004098	0.918852914092727
GO:0048038	quinone binding	5/4868	17/18639	0.294117647058824	1.12614191116052	0.468830941004098	0.918852914092727
GO:0016409	palmitoyltransferase activity	10/4868	36/18639	0.277777777777778	1.0635784716516	0.473065796991403	0.925777130907508
GO:0140312	cargo adaptor activity	6/4868	21/18639	0.285714285714286	1.09396642798451	0.480804577616199	0.938215007970149
GO:0004177	aminopeptidase activity	11/4868	40/18639	0.275	1.05294268693509	0.480844082932389	0.938215007970149
GO:0000030	mannosyltransferase activity	7/4868	25/18639	0.28	1.07208709942482	0.490545595013112	0.952915522565971
GO:0019706	protein-cysteine S-palmitoyltransferase activity	7/4868	25/18639	0.28	1.07208709942482	0.490545595013112	0.952915522565971
GO:0019707	protein-cysteine S-acyltransferase activity	7/4868	25/18639	0.28	1.07208709942482	0.490545595013112	0.952915522565971
GO:0016879	ligase activity, forming carbon-nitrogen bonds	13/4868	48/18639	0.270833333333333	1.03698900986031	0.494232442014003	0.95866557502422
GO:0044325	transmembrane transporter binding	36/4868	136/18639	0.264705882352941	1.01352772004447	0.495365028472937	0.959451501550372
GO:1990782	protein tyrosine kinase binding	31/4868	117/18639	0.264957264957265	1.01449023449845	0.498161136679912	0.963452403637543
GO:0004090	carbonyl reductase (NADPH) activity	3/4868	10/18639	0.3	1.14866474938373	0.507712277944474	0.966338376058819
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	3/4868	10/18639	0.3	1.14866474938373	0.507712277944474	0.966338376058819
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/4868	10/18639	0.3	1.14866474938373	0.507712277944474	0.966338376058819
GO:0005031	tumor necrosis factor receptor activity	3/4868	10/18639	0.3	1.14866474938373	0.507712277944474	0.966338376058819
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/4868	10/18639	0.3	1.14866474938373	0.507712277944474	0.966338376058819
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/4868	10/18639	0.3	1.14866474938373	0.507712277944474	0.966338376058819
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	3/4868	10/18639	0.3	1.14866474938373	0.507712277944474	0.966338376058819
GO:0016868	intramolecular phosphotransferase activity	3/4868	10/18639	0.3	1.14866474938373	0.507712277944474	0.966338376058819
GO:0031419	cobalamin binding	3/4868	10/18639	0.3	1.14866474938373	0.507712277944474	0.966338376058819
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/4868	10/18639	0.3	1.14866474938373	0.507712277944474	0.966338376058819
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/4868	10/18639	0.3	1.14866474938373	0.507712277944474	0.966338376058819
GO:0008559	ABC-type xenobiotic transporter activity	4/4868	14/18639	0.285714285714286	1.09396642798451	0.517715576441011	0.977645358942756
GO:0016530	metallochaperone activity	4/4868	14/18639	0.285714285714286	1.09396642798451	0.517715576441011	0.977645358942756
GO:0042043	neurexin family protein binding	4/4868	14/18639	0.285714285714286	1.09396642798451	0.517715576441011	0.977645358942756
GO:0004812	aminoacyl-tRNA ligase activity	11/4868	41/18639	0.268292682926829	1.02726115798545	0.518100156103856	0.977645358942756
GO:0015175	neutral L-amino acid transmembrane transporter activity	11/4868	41/18639	0.268292682926829	1.02726115798545	0.518100156103856	0.977645358942756
GO:0016875	ligase activity, forming carbon-oxygen bonds	11/4868	41/18639	0.268292682926829	1.02726115798545	0.518100156103856	0.977645358942756
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	5/4868	18/18639	0.277777777777778	1.0635784716516	0.525388036481819	0.987160712420968
GO:0031690	adrenergic receptor binding	5/4868	18/18639	0.277777777777778	1.0635784716516	0.525388036481819	0.987160712420968
GO:0035615	clathrin adaptor activity	5/4868	18/18639	0.277777777777778	1.0635784716516	0.525388036481819	0.987160712420968
GO:0008093	cytoskeletal anchor activity	6/4868	22/18639	0.272727272727273	1.04424068125794	0.531744307428343	0.997682420338528
GO:0008198	ferrous iron binding	7/4868	26/18639	0.269230769230769	1.03085298021617	0.537247577815817	1
GO:0070412	R-SMAD binding	7/4868	26/18639	0.269230769230769	1.03085298021617	0.537247577815817	1
GO:0001965	G-protein alpha-subunit binding	8/4868	30/18639	0.266666666666667	1.02103533278554	0.542148294041564	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	12/4868	46/18639	0.260869565217391	0.998838912507592	0.558082313043149	1
GO:0030971	receptor tyrosine kinase binding	21/4868	81/18639	0.259259259259259	0.992673240208162	0.558119118399136	1
GO:0004129	cytochrome-c oxidase activity	4/4868	15/18639	0.266666666666667	1.02103533278554	0.578383842438129	1
GO:0004467	long-chain fatty acid-CoA ligase activity	4/4868	15/18639	0.266666666666667	1.02103533278554	0.578383842438129	1
GO:0004559	alpha-mannosidase activity	4/4868	15/18639	0.266666666666667	1.02103533278554	0.578383842438129	1
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/4868	15/18639	0.266666666666667	1.02103533278554	0.578383842438129	1
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/4868	15/18639	0.266666666666667	1.02103533278554	0.578383842438129	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/4868	15/18639	0.266666666666667	1.02103533278554	0.578383842438129	1
GO:0017081	chloride channel regulator activity	4/4868	15/18639	0.266666666666667	1.02103533278554	0.578383842438129	1
GO:0050780	dopamine receptor binding	4/4868	15/18639	0.266666666666667	1.02103533278554	0.578383842438129	1
GO:0004016	adenylate cyclase activity	3/4868	11/18639	0.272727272727273	1.04424068125794	0.578910677828179	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	3/4868	11/18639	0.272727272727273	1.04424068125794	0.578910677828179	1
GO:0008526	phosphatidylinositol transfer activity	3/4868	11/18639	0.272727272727273	1.04424068125794	0.578910677828179	1
GO:0015217	ADP transmembrane transporter activity	3/4868	11/18639	0.272727272727273	1.04424068125794	0.578910677828179	1
GO:0034713	type I transforming growth factor beta receptor binding	3/4868	11/18639	0.272727272727273	1.04424068125794	0.578910677828179	1
GO:0035252	UDP-xylosyltransferase activity	3/4868	11/18639	0.272727272727273	1.04424068125794	0.578910677828179	1
GO:0042285	xylosyltransferase activity	3/4868	11/18639	0.272727272727273	1.04424068125794	0.578910677828179	1
GO:0047676	arachidonate-CoA ligase activity	3/4868	11/18639	0.272727272727273	1.04424068125794	0.578910677828179	1
GO:0050786	RAGE receptor binding	3/4868	11/18639	0.272727272727273	1.04424068125794	0.578910677828179	1
GO:0070697	activin receptor binding	3/4868	11/18639	0.272727272727273	1.04424068125794	0.578910677828179	1
GO:0015245	fatty acid transmembrane transporter activity	5/4868	19/18639	0.263157894736842	1.00760065735415	0.579113957878111	1
GO:0034987	immunoglobulin receptor binding	5/4868	19/18639	0.263157894736842	1.00760065735415	0.579113957878111	1
GO:0097001	ceramide binding	5/4868	19/18639	0.263157894736842	1.00760065735415	0.579113957878111	1
GO:0072349	modified amino acid transmembrane transporter activity	8/4868	31/18639	0.258064516129032	0.988098709147295	0.583931610293353	1
GO:0008375	acetylglucosaminyltransferase activity	11/4868	43/18639	0.255813953488372	0.979481569241941	0.589809253605374	1
GO:0016248	channel inhibitor activity	11/4868	44/18639	0.25	0.957220624486442	0.623795608840045	1
GO:0032266	phosphatidylinositol-3-phosphate binding	12/4868	48/18639	0.25	0.957220624486442	0.624322025426072	1
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	7/4868	28/18639	0.25	0.957220624486442	0.624714593116289	1
GO:0005319	lipid transporter activity	45/4868	178/18639	0.252808988764045	0.96797591240202	0.628887465442085	1
GO:0001972	retinoic acid binding	5/4868	20/18639	0.25	0.957220624486442	0.629393379690953	1
GO:0004707	MAP kinase activity	4/4868	16/18639	0.25	0.957220624486442	0.634413383629626	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/4868	16/18639	0.25	0.957220624486442	0.634413383629626	1
GO:0003720	telomerase activity	3/4868	12/18639	0.25	0.957220624486442	0.643204210584089	1
GO:0005165	neurotrophin receptor binding	3/4868	12/18639	0.25	0.957220624486442	0.643204210584089	1
GO:0010853	cyclase activator activity	3/4868	12/18639	0.25	0.957220624486442	0.643204210584089	1
GO:0016801	hydrolase activity, acting on ether bonds	3/4868	12/18639	0.25	0.957220624486442	0.643204210584089	1
GO:0016803	ether hydrolase activity	3/4868	12/18639	0.25	0.957220624486442	0.643204210584089	1
GO:0035259	nuclear glucocorticoid receptor binding	3/4868	12/18639	0.25	0.957220624486442	0.643204210584089	1
GO:0035497	cAMP response element binding	3/4868	12/18639	0.25	0.957220624486442	0.643204210584089	1
GO:0070008	serine-type exopeptidase activity	3/4868	12/18639	0.25	0.957220624486442	0.643204210584089	1
GO:0070679	inositol 1,4,5 trisphosphate binding	3/4868	12/18639	0.25	0.957220624486442	0.643204210584089	1
GO:0004864	protein phosphatase inhibitor activity	13/4868	53/18639	0.245283018867925	0.939159857986698	0.654999295368596	1
GO:1901505	carbohydrate derivative transmembrane transporter activity	13/4868	53/18639	0.245283018867925	0.939159857986698	0.654999295368596	1
GO:0046915	transition metal ion transmembrane transporter activity	11/4868	45/18639	0.244444444444444	0.93594905505341	0.656289796274069	1
GO:0141110	transporter inhibitor activity	11/4868	45/18639	0.244444444444444	0.93594905505341	0.656289796274069	1
GO:0042287	MHC protein binding	10/4868	41/18639	0.24390243902439	0.933873779986773	0.657473612321166	1
GO:0023023	MHC protein complex binding	9/4868	37/18639	0.243243243243243	0.931349796797619	0.659159921840754	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	8/4868	33/18639	0.242424242424242	0.928213938895944	0.661514027436333	1
GO:0003785	actin monomer binding	7/4868	29/18639	0.241379310344828	0.92421301674553	0.664781166831658	1
GO:0004629	phospholipase C activity	7/4868	29/18639	0.241379310344828	0.92421301674553	0.664781166831658	1
GO:0008483	transaminase activity	6/4868	25/18639	0.24	0.918931799506984	0.669342532053335	1
GO:0008373	sialyltransferase activity	5/4868	21/18639	0.238095238095238	0.911638689987088	0.675827380339314	1
GO:0015485	cholesterol binding	13/4868	54/18639	0.240740740740741	0.921768008764722	0.683641333864043	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	4/4868	17/18639	0.235294117647059	0.900913528928416	0.685361827514404	1
GO:0016805	dipeptidase activity	4/4868	17/18639	0.235294117647059	0.900913528928416	0.685361827514404	1
GO:0019198	transmembrane receptor protein phosphatase activity	4/4868	17/18639	0.235294117647059	0.900913528928416	0.685361827514404	1
GO:0036041	long-chain fatty acid binding	4/4868	17/18639	0.235294117647059	0.900913528928416	0.685361827514404	1
GO:0046965	nuclear retinoid X receptor binding	4/4868	17/18639	0.235294117647059	0.900913528928416	0.685361827514404	1
GO:0003964	RNA-directed DNA polymerase activity	3/4868	13/18639	0.230769230769231	0.883588268756716	0.700205827449081	1
GO:0005542	folic acid binding	3/4868	13/18639	0.230769230769231	0.883588268756716	0.700205827449081	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/4868	13/18639	0.230769230769231	0.883588268756716	0.700205827449081	1
GO:0019855	calcium channel inhibitor activity	3/4868	13/18639	0.230769230769231	0.883588268756716	0.700205827449081	1
GO:0031432	titin binding	3/4868	13/18639	0.230769230769231	0.883588268756716	0.700205827449081	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/4868	13/18639	0.230769230769231	0.883588268756716	0.700205827449081	1
GO:0061459	L-arginine transmembrane transporter activity	3/4868	13/18639	0.230769230769231	0.883588268756716	0.700205827449081	1
GO:0071837	HMG box domain binding	3/4868	13/18639	0.230769230769231	0.883588268756716	0.700205827449081	1
GO:0089720	caspase binding	3/4868	13/18639	0.230769230769231	0.883588268756716	0.700205827449081	1
GO:0016769	transferase activity, transferring nitrogenous groups	7/4868	30/18639	0.233333333333333	0.893405916187346	0.70210421507212	1
GO:0031210	phosphatidylcholine binding	7/4868	30/18639	0.233333333333333	0.893405916187346	0.70210421507212	1
GO:0004435	phosphatidylinositol phospholipase C activity	6/4868	26/18639	0.230769230769231	0.883588268756716	0.708971018324591	1
GO:0005160	transforming growth factor beta receptor binding	6/4868	26/18639	0.230769230769231	0.883588268756716	0.708971018324591	1
GO:0015216	purine nucleotide transmembrane transporter activity	6/4868	26/18639	0.230769230769231	0.883588268756716	0.708971018324591	1
GO:0140359	ABC-type transporter activity	11/4868	47/18639	0.234042553191489	0.896121435689435	0.716291370091748	1
GO:0008200	ion channel inhibitor activity	10/4868	43/18639	0.232558139534884	0.890437790219946	0.719906055158267	1
GO:0015172	acidic amino acid transmembrane transporter activity	4/4868	18/18639	0.222222222222222	0.850862777321282	0.731068624952285	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	4/4868	18/18639	0.222222222222222	0.850862777321282	0.731068624952285	1
GO:0030170	pyridoxal phosphate binding	13/4868	56/18639	0.232142857142857	0.888847722737411	0.736553747620401	1
GO:0016411	acylglycerol O-acyltransferase activity	7/4868	31/18639	0.225806451612903	0.864586370503883	0.736571224799261	1
GO:0016758	hexosyltransferase activity	48/4868	197/18639	0.243654822335025	0.932925684778664	0.737811556054706	1
GO:0005385	zinc ion transmembrane transporter activity	6/4868	27/18639	0.222222222222222	0.850862777321282	0.745218633746012	1
GO:0016405	CoA-ligase activity	6/4868	27/18639	0.222222222222222	0.850862777321282	0.745218633746012	1
GO:0004705	JUN kinase activity	3/4868	14/18639	0.214285714285714	0.820474820988379	0.749975895905827	1
GO:0005347	ATP transmembrane transporter activity	3/4868	14/18639	0.214285714285714	0.820474820988379	0.749975895905827	1
GO:0015386	potassium:proton antiporter activity	3/4868	14/18639	0.214285714285714	0.820474820988379	0.749975895905827	1
GO:0015926	glucosidase activity	3/4868	14/18639	0.214285714285714	0.820474820988379	0.749975895905827	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/4868	14/18639	0.214285714285714	0.820474820988379	0.749975895905827	1
GO:0031404	chloride ion binding	3/4868	14/18639	0.214285714285714	0.820474820988379	0.749975895905827	1
GO:0032036	myosin heavy chain binding	3/4868	14/18639	0.214285714285714	0.820474820988379	0.749975895905827	1
GO:1901474	azole transmembrane transporter activity	3/4868	14/18639	0.214285714285714	0.820474820988379	0.749975895905827	1
GO:0071949	FAD binding	9/4868	40/18639	0.225	0.861498562037798	0.753598544603018	1
GO:0000295	adenine nucleotide transmembrane transporter activity	5/4868	23/18639	0.217391304347826	0.832365760422993	0.75646991548174	1
GO:0070279	vitamin B6 binding	13/4868	57/18639	0.228070175438596	0.873253903040263	0.76072377273135	1
GO:0015297	antiporter activity	32/4868	135/18639	0.237037037037037	0.907586962476034	0.767862728690319	1
GO:0120015	sterol transfer activity	7/4868	32/18639	0.21875	0.837568046425637	0.768145509976151	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	4/4868	19/18639	0.210526315789474	0.80608052588332	0.771589869505399	1
GO:0042800	histone H3K4 methyltransferase activity	4/4868	19/18639	0.210526315789474	0.80608052588332	0.771589869505399	1
GO:0046875	ephrin receptor binding	6/4868	28/18639	0.214285714285714	0.820474820988379	0.778083372099572	1
GO:0005381	iron ion transmembrane transporter activity	2/4868	10/18639	0.2	0.765776499589154	0.780288313997402	1
GO:0015187	glycine transmembrane transporter activity	2/4868	10/18639	0.2	0.765776499589154	0.780288313997402	1
GO:0015643	toxic substance binding	2/4868	10/18639	0.2	0.765776499589154	0.780288313997402	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/4868	10/18639	0.2	0.765776499589154	0.780288313997402	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	2/4868	10/18639	0.2	0.765776499589154	0.780288313997402	1
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/4868	10/18639	0.2	0.765776499589154	0.780288313997402	1
GO:0019531	oxalate transmembrane transporter activity	2/4868	10/18639	0.2	0.765776499589154	0.780288313997402	1
GO:0019911	structural constituent of myelin sheath	2/4868	10/18639	0.2	0.765776499589154	0.780288313997402	1
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/4868	10/18639	0.2	0.765776499589154	0.780288313997402	1
GO:0043295	glutathione binding	2/4868	10/18639	0.2	0.765776499589154	0.780288313997402	1
GO:0141109	transporter activator activity	2/4868	10/18639	0.2	0.765776499589154	0.780288313997402	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	5/4868	24/18639	0.208333333333333	0.797683853738702	0.790690612407545	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	5/4868	24/18639	0.208333333333333	0.797683853738702	0.790690612407545	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	5/4868	24/18639	0.208333333333333	0.797683853738702	0.790690612407545	1
GO:0050699	WW domain binding	5/4868	24/18639	0.208333333333333	0.797683853738702	0.790690612407545	1
GO:0005523	tropomyosin binding	3/4868	15/18639	0.2	0.765776499589154	0.792873909272751	1
GO:0031005	filamin binding	3/4868	15/18639	0.2	0.765776499589154	0.792873909272751	1
GO:0047372	monoacylglycerol lipase activity	3/4868	15/18639	0.2	0.765776499589154	0.792873909272751	1
GO:0120283	protein serine/threonine kinase binding	3/4868	15/18639	0.2	0.765776499589154	0.792873909272751	1
GO:0003774	cytoskeletal motor activity	36/4868	153/18639	0.235294117647059	0.900913528928416	0.793719938890644	1
GO:0043178	alcohol binding	21/4868	92/18639	0.228260869565217	0.873984048444143	0.797781387889504	1
GO:0004180	carboxypeptidase activity	10/4868	46/18639	0.217391304347826	0.832365760422993	0.798668473953187	1
GO:0030276	clathrin binding	10/4868	46/18639	0.217391304347826	0.832365760422993	0.798668473953187	1
GO:1901682	sulfur compound transmembrane transporter activity	14/4868	63/18639	0.222222222222222	0.850862777321282	0.800132635226779	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	13/4868	59/18639	0.220338983050847	0.843652075818559	0.804405430432982	1
GO:0015095	magnesium ion transmembrane transporter activity	4/4868	20/18639	0.2	0.765776499589154	0.80713899195901	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/4868	29/18639	0.206896551724138	0.792182585781883	0.807640469125985	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	30/4868	130/18639	0.230769230769231	0.883588268756716	0.812979573396978	1
GO:0016597	amino acid binding	11/4868	51/18639	0.215686274509804	0.825837401517715	0.814696336629899	1
GO:0032934	sterol binding	15/4868	68/18639	0.220588235294118	0.84460643337039	0.815278916888959	1
GO:0005504	fatty acid binding	10/4868	47/18639	0.212765957446809	0.814655850626759	0.8209325560779	1
GO:0043495	protein-membrane adaptor activity	10/4868	47/18639	0.212765957446809	0.814655850626759	0.8209325560779	1
GO:0003707	nuclear steroid receptor activity	5/4868	25/18639	0.2	0.765776499589154	0.821027632496097	1
GO:0005537	D-mannose binding	5/4868	25/18639	0.2	0.765776499589154	0.821027632496097	1
GO:0015662	P-type ion transporter activity	5/4868	25/18639	0.2	0.765776499589154	0.821027632496097	1
GO:0140358	P-type transmembrane transporter activity	5/4868	25/18639	0.2	0.765776499589154	0.821027632496097	1
GO:0015101	organic cation transmembrane transporter activity	18/4868	81/18639	0.222222222222222	0.850862777321282	0.822220365599264	1
GO:0008238	exopeptidase activity	23/4868	102/18639	0.225490196078431	0.863375465223065	0.824750454077963	1
GO:0000099	sulfur amino acid transmembrane transporter activity	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0002162	dystroglycan binding	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0005536	D-glucose binding	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0008172	S-methyltransferase activity	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0008271	secondary active sulfate transmembrane transporter activity	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0008432	JUN kinase binding	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0010854	adenylate cyclase regulator activity	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0019215	intermediate filament binding	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0034056	estrogen response element binding	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0045294	alpha-catenin binding	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:1900750	oligopeptide binding	2/4868	11/18639	0.181818181818182	0.696160454171958	0.825038899812784	1
GO:0042626	ATPase-coupled transmembrane transporter activity	22/4868	98/18639	0.224489795918367	0.859545050559254	0.827005836151123	1
GO:0005149	interleukin-1 receptor binding	3/4868	16/18639	0.1875	0.717915468364832	0.829441722882703	1
GO:0005159	insulin-like growth factor receptor binding	3/4868	16/18639	0.1875	0.717915468364832	0.829441722882703	1
GO:0015385	sodium:proton antiporter activity	3/4868	16/18639	0.1875	0.717915468364832	0.829441722882703	1
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/4868	16/18639	0.1875	0.717915468364832	0.829441722882703	1
GO:0051015	actin filament binding	49/4868	209/18639	0.23444976076555	0.897680585642788	0.832199323038237	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	6/4868	30/18639	0.2	0.765776499589154	0.834024532639451	1
GO:0033612	receptor serine/threonine kinase binding	6/4868	30/18639	0.2	0.765776499589154	0.834024532639451	1
GO:0010314	phosphatidylinositol-5-phosphate binding	4/4868	21/18639	0.19047619047619	0.72931095198967	0.83803584175188	1
GO:0015174	basic amino acid transmembrane transporter activity	4/4868	21/18639	0.19047619047619	0.72931095198967	0.83803584175188	1
GO:0016229	steroid dehydrogenase activity	7/4868	35/18639	0.2	0.765776499589154	0.846026793855311	1
GO:0004601	peroxidase activity	12/4868	57/18639	0.210526315789474	0.80608052588332	0.847267660145712	1
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/4868	26/18639	0.192307692307692	0.736323557297263	0.847707778727408	1
GO:0016782	transferase activity, transferring sulphur-containing groups	15/4868	70/18639	0.214285714285714	0.820474820988379	0.849236935186162	1
GO:0005516	calmodulin binding	48/4868	207/18639	0.231884057971014	0.887856811117859	0.852137462835454	1
GO:0008235	metalloexopeptidase activity	14/4868	66/18639	0.212121212121212	0.812187196533951	0.853679308786475	1
GO:0033293	monocarboxylic acid binding	17/4868	79/18639	0.215189873417722	0.823936740064279	0.85636977371438	1
GO:0050997	quaternary ammonium group binding	8/4868	40/18639	0.2	0.765776499589154	0.857060790870968	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	6/4868	31/18639	0.193548387096774	0.741074031860471	0.857413326521096	1
GO:0005452	solute:inorganic anion antiporter activity	6/4868	31/18639	0.193548387096774	0.741074031860471	0.857413326521096	1
GO:0015179	L-amino acid transmembrane transporter activity	13/4868	62/18639	0.209677419354839	0.802830201182177	0.858561965751743	1
GO:0015278	intracellularly gated calcium channel activity	3/4868	17/18639	0.176470588235294	0.675685146696312	0.86031598617591	1
GO:0004000	adenosine deaminase activity	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0005025	transforming growth factor beta receptor activity, type I	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0005026	transforming growth factor beta receptor activity, type II	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0005247	voltage-gated chloride channel activity	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0005436	sodium:phosphate symporter activity	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0008179	adenylate cyclase binding	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0015166	polyol transmembrane transporter activity	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0015368	calcium:monoatomic cation antiporter activity	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0016208	AMP binding	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0016361	activin receptor activity, type I	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0016362	activin receptor activity, type II	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0017002	activin receptor activity	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0017166	vinculin binding	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0031543	peptidyl-proline dioxygenase activity	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0045295	gamma-catenin binding	2/4868	12/18639	0.166666666666667	0.638147082990961	0.861405837658523	1
GO:0015377	chloride:monoatomic cation symporter activity	4/4868	22/18639	0.181818181818182	0.696160454171958	0.864664972202321	1
GO:0016881	acid-amino acid ligase activity	4/4868	22/18639	0.181818181818182	0.696160454171958	0.864664972202321	1
GO:0031683	G-protein beta/gamma-subunit complex binding	4/4868	22/18639	0.181818181818182	0.696160454171958	0.864664972202321	1
GO:0004033	aldo-keto reductase (NADPH) activity	7/4868	36/18639	0.194444444444444	0.744504930156122	0.866756906532305	1
GO:0045505	dynein intermediate chain binding	7/4868	36/18639	0.194444444444444	0.744504930156122	0.866756906532305	1
GO:0042605	peptide antigen binding	9/4868	45/18639	0.2	0.765776499589154	0.867193823242078	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	27/4868	122/18639	0.221311475409836	0.847375634791277	0.867254363040977	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	11/4868	54/18639	0.203703703703704	0.779957545877842	0.869896959398337	1
GO:0015252	proton channel activity	5/4868	27/18639	0.185185185185185	0.709052314434402	0.87100076622318	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	5/4868	27/18639	0.185185185185185	0.709052314434402	0.87100076622318	1
GO:0023026	MHC class II protein complex binding	5/4868	27/18639	0.185185185185185	0.709052314434402	0.87100076622318	1
GO:0140828	metal cation:monoatomic cation antiporter activity	8/4868	41/18639	0.195121951219512	0.747099023989418	0.875588574886406	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/4868	32/18639	0.1875	0.717915468364832	0.878013591877622	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	29/4868	132/18639	0.21969696969697	0.841193882124449	0.884071126707801	1
GO:0016854	racemase and epimerase activity	3/4868	18/18639	0.166666666666667	0.638147082990961	0.886165458420635	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	3/4868	18/18639	0.166666666666667	0.638147082990961	0.886165458420635	1
GO:0017075	syntaxin-1 binding	3/4868	18/18639	0.166666666666667	0.638147082990961	0.886165458420635	1
GO:0032393	MHC class I receptor activity	3/4868	18/18639	0.166666666666667	0.638147082990961	0.886165458420635	1
GO:0070064	proline-rich region binding	3/4868	18/18639	0.166666666666667	0.638147082990961	0.886165458420635	1
GO:0098641	cadherin binding involved in cell-cell adhesion	3/4868	18/18639	0.166666666666667	0.638147082990961	0.886165458420635	1
GO:0004602	glutathione peroxidase activity	4/4868	23/18639	0.173913043478261	0.665892608338394	0.887442878880338	1
GO:0005158	insulin receptor binding	4/4868	23/18639	0.173913043478261	0.665892608338394	0.887442878880338	1
GO:0031681	G-protein beta-subunit binding	4/4868	23/18639	0.173913043478261	0.665892608338394	0.887442878880338	1
GO:0001216	DNA-binding transcription activator activity	117/4868	491/18639	0.238289205702648	0.912381369164266	0.889916701262409	1
GO:0017154	semaphorin receptor activity	2/4868	13/18639	0.153846153846154	0.589058845837811	0.890714930423877	1
GO:0045159	myosin II binding	2/4868	13/18639	0.153846153846154	0.589058845837811	0.890714930423877	1
GO:0070123	transforming growth factor beta receptor activity, type III	2/4868	13/18639	0.153846153846154	0.589058845837811	0.890714930423877	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/4868	13/18639	0.153846153846154	0.589058845837811	0.890714930423877	1
GO:0046625	sphingolipid binding	5/4868	28/18639	0.178571428571429	0.683729017490316	0.891200199728312	1
GO:0051959	dynein light intermediate chain binding	5/4868	28/18639	0.178571428571429	0.683729017490316	0.891200199728312	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	115/4868	484/18639	0.237603305785124	0.909755138974718	0.894943427847271	1
GO:0019956	chemokine binding	6/4868	33/18639	0.181818181818182	0.696160454171958	0.896049059840524	1
GO:0005315	phosphate transmembrane transporter activity	4/4868	24/18639	0.166666666666667	0.638147082990961	0.906793332174897	1
GO:0030552	cAMP binding	4/4868	24/18639	0.166666666666667	0.638147082990961	0.906793332174897	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/4868	24/18639	0.166666666666667	0.638147082990961	0.906793332174897	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	3/4868	19/18639	0.157894736842105	0.60456039441249	0.907648381342242	1
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/4868	19/18639	0.157894736842105	0.60456039441249	0.907648381342242	1
GO:0008574	plus-end-directed microtubule motor activity	3/4868	19/18639	0.157894736842105	0.60456039441249	0.907648381342242	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/4868	19/18639	0.157894736842105	0.60456039441249	0.907648381342242	1
GO:0022821	solute:potassium antiporter activity	3/4868	19/18639	0.157894736842105	0.60456039441249	0.907648381342242	1
GO:0031420	alkali metal ion binding	3/4868	19/18639	0.157894736842105	0.60456039441249	0.907648381342242	1
GO:0008376	acetylgalactosaminyltransferase activity	6/4868	34/18639	0.176470588235294	0.675685146696312	0.911750643364867	1
GO:0051427	hormone receptor binding	6/4868	34/18639	0.176470588235294	0.675685146696312	0.911750643364867	1
GO:0005161	platelet-derived growth factor receptor binding	2/4868	14/18639	0.142857142857143	0.546983213992253	0.914171436176885	1
GO:0005344	oxygen carrier activity	2/4868	14/18639	0.142857142857143	0.546983213992253	0.914171436176885	1
GO:0005545	1-phosphatidylinositol binding	2/4868	14/18639	0.142857142857143	0.546983213992253	0.914171436176885	1
GO:0008195	phosphatidate phosphatase activity	2/4868	14/18639	0.142857142857143	0.546983213992253	0.914171436176885	1
GO:0019763	immunoglobulin receptor activity	2/4868	14/18639	0.142857142857143	0.546983213992253	0.914171436176885	1
GO:0019992	diacylglycerol binding	2/4868	14/18639	0.142857142857143	0.546983213992253	0.914171436176885	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/4868	14/18639	0.142857142857143	0.546983213992253	0.914171436176885	1
GO:0098821	BMP receptor activity	2/4868	14/18639	0.142857142857143	0.546983213992253	0.914171436176885	1
GO:1901612	cardiolipin binding	2/4868	14/18639	0.142857142857143	0.546983213992253	0.914171436176885	1
GO:0004857	enzyme inhibitor activity	97/4868	416/18639	0.233173076923077	0.892792313222932	0.916123779798689	1
GO:0005543	phospholipid binding	117/4868	497/18639	0.235412474849095	0.901366704747797	0.91688557011483	1
GO:0048306	calcium-dependent protein binding	16/4868	80/18639	0.2	0.765776499589154	0.918873318552579	1
GO:0008194	UDP-glycosyltransferase activity	31/4868	145/18639	0.213793103448276	0.818588671974613	0.921488730542941	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/4868	25/18639	0.16	0.612621199671323	0.92312965592324	1
GO:0015645	fatty acid ligase activity	4/4868	25/18639	0.16	0.612621199671323	0.92312965592324	1
GO:0120020	cholesterol transfer activity	4/4868	25/18639	0.16	0.612621199671323	0.92312965592324	1
GO:0120515	fatty acid-CoA ligase activity	4/4868	25/18639	0.16	0.612621199671323	0.92312965592324	1
GO:0005506	iron ion binding	33/4868	154/18639	0.214285714285714	0.820474820988379	0.924940342989129	1
GO:0010851	cyclase regulator activity	3/4868	20/18639	0.15	0.574332374691865	0.925385332409871	1
GO:0031418	L-ascorbic acid binding	3/4868	20/18639	0.15	0.574332374691865	0.925385332409871	1
GO:0003777	microtubule motor activity	13/4868	68/18639	0.191176470588235	0.731992242254338	0.93120650053399	1
GO:0070888	E-box binding	11/4868	59/18639	0.186440677966102	0.71385944876955	0.931942713879498	1
GO:0004089	carbonate dehydratase activity	2/4868	15/18639	0.133333333333333	0.510517666392769	0.932832594162136	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/4868	15/18639	0.133333333333333	0.510517666392769	0.932832594162136	1
GO:0010181	FMN binding	2/4868	15/18639	0.133333333333333	0.510517666392769	0.932832594162136	1
GO:0015116	sulfate transmembrane transporter activity	2/4868	15/18639	0.133333333333333	0.510517666392769	0.932832594162136	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/4868	15/18639	0.133333333333333	0.510517666392769	0.932832594162136	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	18/4868	91/18639	0.197802197802198	0.757361373220042	0.936676157882435	1
GO:0030247	polysaccharide binding	4/4868	26/18639	0.153846153846154	0.589058845837811	0.9368427245043	1
GO:0050750	low-density lipoprotein particle receptor binding	4/4868	26/18639	0.153846153846154	0.589058845837811	0.9368427245043	1
GO:0008374	O-acyltransferase activity	10/4868	55/18639	0.181818181818182	0.696160454171958	0.937445639769776	1
GO:0001846	opsonin binding	3/4868	21/18639	0.142857142857143	0.546983213992253	0.93994358085287	1
GO:0019200	carbohydrate kinase activity	3/4868	21/18639	0.142857142857143	0.546983213992253	0.93994358085287	1
GO:0098531	ligand-modulated transcription factor activity	11/4868	60/18639	0.183333333333333	0.701961791290057	0.940696745212052	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	13/4868	70/18639	0.185714285714286	0.711078178189928	0.946954989450523	1
GO:0022829	wide pore channel activity	6/4868	37/18639	0.162162162162162	0.620899864531746	0.947118812279075	1
GO:0005024	transforming growth factor beta receptor activity	2/4868	16/18639	0.125	0.478610312243221	0.947602718630626	1
GO:0015378	sodium:chloride symporter activity	2/4868	16/18639	0.125	0.478610312243221	0.947602718630626	1
GO:0016722	oxidoreductase activity, acting on metal ions	2/4868	16/18639	0.125	0.478610312243221	0.947602718630626	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	2/4868	16/18639	0.125	0.478610312243221	0.947602718630626	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/4868	16/18639	0.125	0.478610312243221	0.947602718630626	1
GO:0055102	lipase inhibitor activity	2/4868	16/18639	0.125	0.478610312243221	0.947602718630626	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/4868	16/18639	0.125	0.478610312243221	0.947602718630626	1
GO:0019894	kinesin binding	7/4868	42/18639	0.166666666666667	0.638147082990961	0.948059593281867	1
GO:0004364	glutathione transferase activity	4/4868	27/18639	0.148148148148148	0.567241851547521	0.948293499857538	1
GO:0000182	rDNA binding	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0004382	GDP phosphatase activity	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0004935	adrenergic receptor activity	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0005345	purine nucleobase transmembrane transporter activity	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0008190	eukaryotic initiation factor 4E binding	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0008239	dipeptidyl-peptidase activity	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0008519	ammonium channel activity	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0031434	mitogen-activated protein kinase kinase binding	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0035256	G protein-coupled glutamate receptor binding	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0035374	chondroitin sulfate binding	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0042166	acetylcholine binding	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0043121	neurotrophin binding	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0050308	sugar-phosphatase activity	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0070097	delta-catenin binding	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0071723	lipopeptide binding	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0140999	histone H3K4 trimethyltransferase activity	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:1990763	arrestin family protein binding	1/4868	10/18639	0.1	0.382888249794577	0.951576307248843	1
GO:0008970	phospholipase A1 activity	3/4868	22/18639	0.136363636363636	0.522120340628968	0.951829676955588	1
GO:0046982	protein heterodimerization activity	83/4868	369/18639	0.224932249322493	0.861239152654468	0.953349505495468	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	38/4868	181/18639	0.209944751381215	0.803853784099112	0.954338063048342	1
GO:0030296	protein tyrosine kinase activator activity	5/4868	33/18639	0.151515151515152	0.580133711809965	0.9561238414679	1
GO:0050698	proteoglycan sulfotransferase activity	4/4868	28/18639	0.142857142857143	0.546983213992253	0.957809049879076	1
GO:0051119	sugar transmembrane transporter activity	4/4868	28/18639	0.142857142857143	0.546983213992253	0.957809049879076	1
GO:0030169	low-density lipoprotein particle binding	2/4868	17/18639	0.117647058823529	0.450456764464208	0.959240949624589	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/4868	17/18639	0.117647058823529	0.450456764464208	0.959240949624589	1
GO:0038191	neuropilin binding	2/4868	17/18639	0.117647058823529	0.450456764464208	0.959240949624589	1
GO:0045236	CXCR chemokine receptor binding	2/4868	17/18639	0.117647058823529	0.450456764464208	0.959240949624589	1
GO:0005283	amino acid:sodium symporter activity	3/4868	23/18639	0.130434782608696	0.499419456253796	0.961487696666876	1
GO:0017134	fibroblast growth factor binding	3/4868	23/18639	0.130434782608696	0.499419456253796	0.961487696666876	1
GO:0035254	glutamate receptor binding	8/4868	49/18639	0.163265306122449	0.625123673134003	0.963501605130677	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	5/4868	34/18639	0.147058823529412	0.56307095558026	0.963774392864975	1
GO:0001851	complement component C3b binding	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0003953	NAD+ nucleosidase activity	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0005114	type II transforming growth factor beta receptor binding	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0008046	axon guidance receptor activity	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0008199	ferric iron binding	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0015205	nucleobase transmembrane transporter activity	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0016594	glycine binding	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0019203	carbohydrate phosphatase activity	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0019864	IgG binding	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0032050	clathrin heavy chain binding	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0048185	activin binding	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/4868	11/18639	0.0909090909090909	0.348080227085979	0.964230047992449	1
GO:0008081	phosphoric diester hydrolase activity	16/4868	87/18639	0.183908045977011	0.704162298472785	0.96541977163034	1
GO:0004879	nuclear receptor activity	10/4868	59/18639	0.169491525423729	0.648963135245045	0.965423550058761	1
GO:0051861	glycolipid binding	4/4868	29/18639	0.137931034482759	0.528121723854589	0.965681141549787	1
GO:0030165	PDZ domain binding	15/4868	83/18639	0.180722891566265	0.691966716496223	0.96801738810588	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/4868	18/18639	0.111111111111111	0.425431388660641	0.968375386025083	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/4868	18/18639	0.111111111111111	0.425431388660641	0.968375386025083	1
GO:0005372	water transmembrane transporter activity	2/4868	18/18639	0.111111111111111	0.425431388660641	0.968375386025083	1
GO:0015373	monoatomic anion:sodium symporter activity	2/4868	18/18639	0.111111111111111	0.425431388660641	0.968375386025083	1
GO:0030228	lipoprotein particle receptor activity	2/4868	18/18639	0.111111111111111	0.425431388660641	0.968375386025083	1
GO:0099602	neurotransmitter receptor regulator activity	2/4868	18/18639	0.111111111111111	0.425431388660641	0.968375386025083	1
GO:1901611	phosphatidylglycerol binding	2/4868	18/18639	0.111111111111111	0.425431388660641	0.968375386025083	1
GO:0048029	monosaccharide binding	13/4868	74/18639	0.175675675675676	0.672641519909392	0.969300796168681	1
GO:0004806	triacylglycerol lipase activity	3/4868	24/18639	0.125	0.478610312243221	0.969301177308587	1
GO:0015149	hexose transmembrane transporter activity	3/4868	24/18639	0.125	0.478610312243221	0.969301177308587	1
GO:0015295	solute:proton symporter activity	3/4868	24/18639	0.125	0.478610312243221	0.969301177308587	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/4868	24/18639	0.125	0.478610312243221	0.969301177308587	1
GO:0019957	C-C chemokine binding	3/4868	24/18639	0.125	0.478610312243221	0.969301177308587	1
GO:0055056	D-glucose transmembrane transporter activity	3/4868	24/18639	0.125	0.478610312243221	0.969301177308587	1
GO:0070300	phosphatidic acid binding	3/4868	24/18639	0.125	0.478610312243221	0.969301177308587	1
GO:0004032	aldose reductase (NADPH) activity	1/4868	12/18639	0.0833333333333333	0.319073541495481	0.973577703477351	1
GO:0004859	phospholipase inhibitor activity	1/4868	12/18639	0.0833333333333333	0.319073541495481	0.973577703477351	1
GO:0015132	prostaglandin transmembrane transporter activity	1/4868	12/18639	0.0833333333333333	0.319073541495481	0.973577703477351	1
GO:0015269	calcium-activated potassium channel activity	1/4868	12/18639	0.0833333333333333	0.319073541495481	0.973577703477351	1
GO:0070410	co-SMAD binding	1/4868	12/18639	0.0833333333333333	0.319073541495481	0.973577703477351	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/4868	12/18639	0.0833333333333333	0.319073541495481	0.973577703477351	1
GO:0140900	chloride:bicarbonate antiporter activity	1/4868	12/18639	0.0833333333333333	0.319073541495481	0.973577703477351	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/4868	19/18639	0.105263157894737	0.40304026294166	0.975519739517182	1
GO:0008381	mechanosensitive monoatomic ion channel activity	2/4868	19/18639	0.105263157894737	0.40304026294166	0.975519739517182	1
GO:0042577	lipid phosphatase activity	2/4868	19/18639	0.105263157894737	0.40304026294166	0.975519739517182	1
GO:0042834	peptidoglycan binding	2/4868	19/18639	0.105263157894737	0.40304026294166	0.975519739517182	1
GO:0070003	threonine-type peptidase activity	2/4868	19/18639	0.105263157894737	0.40304026294166	0.975519739517182	1
GO:0141147	intracellularly calcium-gated channel activity	2/4868	19/18639	0.105263157894737	0.40304026294166	0.975519739517182	1
GO:0001848	complement binding	3/4868	25/18639	0.12	0.459465899753492	0.975597293861134	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/4868	25/18639	0.12	0.459465899753492	0.975597293861134	1
GO:0047499	calcium-independent phospholipase A2 activity	4/4868	31/18639	0.129032258064516	0.494049354573648	0.9774892624703	1
GO:0070325	lipoprotein particle receptor binding	4/4868	31/18639	0.129032258064516	0.494049354573648	0.9774892624703	1
GO:0001618	virus receptor activity	14/4868	81/18639	0.172839506172839	0.661782160138775	0.977825633500846	1
GO:0005080	protein kinase C binding	8/4868	52/18639	0.153846153846154	0.589058845837811	0.977991589288575	1
GO:0016209	antioxidant activity	15/4868	86/18639	0.174418604651163	0.66782834266496	0.97873415529094	1
GO:0030551	cyclic nucleotide binding	5/4868	37/18639	0.135135135135135	0.517416553776455	0.979956836391414	1
GO:0008035	high-density lipoprotein particle binding	1/4868	13/18639	0.0769230769230769	0.294529422918905	0.98048293456514	1
GO:0008417	fucosyltransferase activity	1/4868	13/18639	0.0769230769230769	0.294529422918905	0.98048293456514	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/4868	13/18639	0.0769230769230769	0.294529422918905	0.98048293456514	1
GO:0030955	potassium ion binding	1/4868	13/18639	0.0769230769230769	0.294529422918905	0.98048293456514	1
GO:0032396	inhibitory MHC class I receptor activity	1/4868	13/18639	0.0769230769230769	0.294529422918905	0.98048293456514	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/4868	13/18639	0.0769230769230769	0.294529422918905	0.98048293456514	1
GO:0070700	BMP receptor binding	1/4868	13/18639	0.0769230769230769	0.294529422918905	0.98048293456514	1
GO:0071714	icosanoid transmembrane transporter activity	1/4868	13/18639	0.0769230769230769	0.294529422918905	0.98048293456514	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/4868	13/18639	0.0769230769230769	0.294529422918905	0.98048293456514	1
GO:0005227	calcium-activated cation channel activity	3/4868	26/18639	0.115384615384615	0.441794134378358	0.980652237690287	1
GO:0015145	monosaccharide transmembrane transporter activity	3/4868	26/18639	0.115384615384615	0.441794134378358	0.980652237690287	1
GO:0019865	immunoglobulin binding	3/4868	26/18639	0.115384615384615	0.441794134378358	0.980652237690287	1
GO:0140272	exogenous protein binding	14/4868	82/18639	0.170731707317073	0.653711645990741	0.980775414639566	1
GO:0015464	acetylcholine receptor activity	2/4868	20/18639	0.1	0.382888249794577	0.981090229195772	1
GO:0030627	pre-mRNA 5'-splice site binding	2/4868	20/18639	0.1	0.382888249794577	0.981090229195772	1
GO:0005544	calcium-dependent phospholipid binding	8/4868	53/18639	0.150943396226415	0.577944527991814	0.981496220826514	1
GO:0005507	copper ion binding	10/4868	63/18639	0.158730158730159	0.607759126658058	0.981603878174469	1
GO:0038187	pattern recognition receptor activity	7/4868	48/18639	0.145833333333333	0.558378697617091	0.981812756241708	1
GO:0015106	bicarbonate transmembrane transporter activity	4/4868	32/18639	0.125	0.478610312243221	0.981841785419288	1
GO:0042910	xenobiotic transmembrane transporter activity	4/4868	32/18639	0.125	0.478610312243221	0.981841785419288	1
GO:0047498	calcium-dependent phospholipase A2 activity	4/4868	32/18639	0.125	0.478610312243221	0.981841785419288	1
GO:0008013	beta-catenin binding	19/4868	106/18639	0.179245283018868	0.686309126990279	0.982340951155417	1
GO:0031406	carboxylic acid binding	37/4868	187/18639	0.197860962566845	0.757586376598895	0.982763852779274	1
GO:1902936	phosphatidylinositol bisphosphate binding	20/4868	111/18639	0.18018018018018	0.689888738368607	0.983197369145806	1
GO:0005501	retinoid binding	5/4868	38/18639	0.131578947368421	0.503800328677075	0.983631592879633	1
GO:0019840	isoprenoid binding	5/4868	38/18639	0.131578947368421	0.503800328677075	0.983631592879633	1
GO:0042277	peptide binding	51/4868	249/18639	0.204819277108434	0.784228945362386	0.984431931012188	1
GO:0035255	ionotropic glutamate receptor binding	3/4868	27/18639	0.111111111111111	0.425431388660641	0.98469707991938	1
GO:0022804	active transmembrane transporter activity	100/4868	457/18639	0.218818380743982	0.837829868259468	0.985119278540396	1
GO:0005200	structural constituent of cytoskeleton	20/4868	112/18639	0.178571428571429	0.683729017490316	0.985223784720646	1
GO:0036122	BMP binding	2/4868	21/18639	0.0952380952380952	0.364655475994835	0.98542145533713	1
GO:0051428	peptide hormone receptor binding	2/4868	21/18639	0.0952380952380952	0.364655475994835	0.98542145533713	1
GO:0061891	calcium ion sensor activity	2/4868	21/18639	0.0952380952380952	0.364655475994835	0.98542145533713	1
GO:0005313	L-glutamate transmembrane transporter activity	1/4868	14/18639	0.0714285714285714	0.273491606996126	0.985583819056545	1
GO:0008191	metalloendopeptidase inhibitor activity	1/4868	14/18639	0.0714285714285714	0.273491606996126	0.985583819056545	1
GO:0008392	arachidonate epoxygenase activity	1/4868	14/18639	0.0714285714285714	0.273491606996126	0.985583819056545	1
GO:0008494	translation activator activity	1/4868	14/18639	0.0714285714285714	0.273491606996126	0.985583819056545	1
GO:0042813	Wnt receptor activity	1/4868	14/18639	0.0714285714285714	0.273491606996126	0.985583819056545	1
GO:0043176	amine binding	1/4868	14/18639	0.0714285714285714	0.273491606996126	0.985583819056545	1
GO:0043177	organic acid binding	37/4868	189/18639	0.195767195767196	0.749569589544939	0.985933845678023	1
GO:0019842	vitamin binding	28/4868	150/18639	0.186666666666667	0.714724732949877	0.987623891637358	1
GO:0003779	actin binding	96/4868	443/18639	0.216704288939052	0.829735259148519	0.987683825341707	1
GO:0004620	phospholipase activity	19/4868	109/18639	0.174311926605505	0.667419884963024	0.988113525568287	1
GO:0090482	vitamin transmembrane transporter activity	4/4868	34/18639	0.117647058823529	0.450456764464208	0.988271047389045	1
GO:0033038	bitter taste receptor activity	2/4868	22/18639	0.0909090909090909	0.348080227085979	0.988780633175284	1
GO:0140784	metal ion sensor activity	2/4868	22/18639	0.0909090909090909	0.348080227085979	0.988780633175284	1
GO:0170055	lipid transmembrane transporter activity	8/4868	56/18639	0.142857142857143	0.546983213992253	0.989149600880387	1
GO:0015144	carbohydrate transmembrane transporter activity	5/4868	40/18639	0.125	0.478610312243221	0.989161223920147	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	14/4868	86/18639	0.162790697674419	0.623306453153962	0.989336311590517	1
GO:0005041	low-density lipoprotein particle receptor activity	1/4868	15/18639	0.0666666666666667	0.255258833196385	0.98935176369186	1
GO:0015250	water channel activity	1/4868	15/18639	0.0666666666666667	0.255258833196385	0.98935176369186	1
GO:0015929	hexosaminidase activity	1/4868	15/18639	0.0666666666666667	0.255258833196385	0.98935176369186	1
GO:0033130	acetylcholine receptor binding	1/4868	15/18639	0.0666666666666667	0.255258833196385	0.98935176369186	1
GO:0034483	heparan sulfate sulfotransferase activity	1/4868	15/18639	0.0666666666666667	0.255258833196385	0.98935176369186	1
GO:0045504	dynein heavy chain binding	1/4868	15/18639	0.0666666666666667	0.255258833196385	0.98935176369186	1
GO:0140161	monocarboxylate:sodium symporter activity	1/4868	15/18639	0.0666666666666667	0.255258833196385	0.98935176369186	1
GO:0005416	amino acid:monoatomic cation symporter activity	3/4868	29/18639	0.103448275862069	0.396091292890942	0.990490086059728	1
GO:0099604	ligand-gated calcium channel activity	3/4868	29/18639	0.103448275862069	0.396091292890942	0.990490086059728	1
GO:0004623	phospholipase A2 activity	4/4868	35/18639	0.114285714285714	0.437586571193802	0.990605546646548	1
GO:0070851	growth factor receptor binding	25/4868	139/18639	0.179856115107914	0.68864793128521	0.99102625476603	1
GO:0001530	lipopolysaccharide binding	5/4868	41/18639	0.121951219512195	0.466936889993386	0.991209668219376	1
GO:0017080	sodium channel regulator activity	5/4868	41/18639	0.121951219512195	0.466936889993386	0.991209668219376	1
GO:0005212	structural constituent of eye lens	2/4868	23/18639	0.0869565217391304	0.332946304169197	0.991379960461799	1
GO:0016493	C-C chemokine receptor activity	2/4868	23/18639	0.0869565217391304	0.332946304169197	0.991379960461799	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	7/4868	52/18639	0.134615384615385	0.515426490108084	0.991392244790666	1
GO:0033218	amide binding	49/4868	247/18639	0.198380566801619	0.759575880159282	0.991647861294165	1
GO:0008391	arachidonate monooxygenase activity	1/4868	16/18639	0.0625	0.239305156121611	0.992135033362609	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/4868	36/18639	0.111111111111111	0.425431388660641	0.992491331781689	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/4868	30/18639	0.1	0.382888249794577	0.992526022188984	1
GO:0022839	monoatomic ion-gated channel activity	3/4868	30/18639	0.1	0.382888249794577	0.992526022188984	1
GO:0005246	calcium channel regulator activity	7/4868	53/18639	0.132075471698113	0.505701461992837	0.992898161480863	1
GO:0005496	steroid binding	18/4868	108/18639	0.166666666666667	0.638147082990961	0.992902528424447	1
GO:0005540	hyaluronic acid binding	2/4868	24/18639	0.0833333333333333	0.319073541495481	0.993387122566636	1
GO:0030215	semaphorin receptor binding	2/4868	24/18639	0.0833333333333333	0.319073541495481	0.993387122566636	1
GO:0046943	carboxylic acid transmembrane transporter activity	35/4868	188/18639	0.186170212765957	0.712823869298414	0.994028423092886	1
GO:0017147	Wnt-protein binding	3/4868	31/18639	0.0967741935483871	0.370537015930236	0.994137103587414	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/4868	17/18639	0.0588235294117647	0.225228382232104	0.994190913596235	1
GO:0008484	sulfuric ester hydrolase activity	1/4868	17/18639	0.0588235294117647	0.225228382232104	0.994190913596235	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/4868	17/18639	0.0588235294117647	0.225228382232104	0.994190913596235	1
GO:0030548	acetylcholine receptor regulator activity	1/4868	17/18639	0.0588235294117647	0.225228382232104	0.994190913596235	1
GO:0008237	metallopeptidase activity	34/4868	184/18639	0.184782608695652	0.707510896359544	0.994376755201825	1
GO:0005342	organic acid transmembrane transporter activity	35/4868	189/18639	0.185185185185185	0.709052314434402	0.994670944609868	1
GO:0000146	microfilament motor activity	4/4868	38/18639	0.105263157894737	0.40304026294166	0.995231731812343	1
GO:0005109	frizzled binding	4/4868	38/18639	0.105263157894737	0.40304026294166	0.995231731812343	1
GO:0016298	lipase activity	22/4868	130/18639	0.169230769230769	0.647964730421592	0.995323174970055	1
GO:0071813	lipoprotein particle binding	3/4868	32/18639	0.09375	0.358957734182416	0.995409033053082	1
GO:0071814	protein-lipid complex binding	3/4868	32/18639	0.09375	0.358957734182416	0.995409033053082	1
GO:0015280	ligand-gated sodium channel activity	1/4868	18/18639	0.0555555555555556	0.21271569433032	0.995709474041597	1
GO:0034185	apolipoprotein binding	1/4868	18/18639	0.0555555555555556	0.21271569433032	0.995709474041597	1
GO:0001637	G protein-coupled chemoattractant receptor activity	2/4868	26/18639	0.0769230769230769	0.294529422918905	0.996124216401778	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	2/4868	26/18639	0.0769230769230769	0.294529422918905	0.996124216401778	1
GO:0004950	chemokine receptor activity	2/4868	26/18639	0.0769230769230769	0.294529422918905	0.996124216401778	1
GO:0008514	organic anion transmembrane transporter activity	52/4868	269/18639	0.193308550185874	0.740155724509963	0.996502550642841	1
GO:0004890	GABA-A receptor activity	1/4868	19/18639	0.0526315789473684	0.20152013147083	0.99683112595962	1
GO:0005520	insulin-like growth factor binding	1/4868	19/18639	0.0526315789473684	0.20152013147083	0.99683112595962	1
GO:0030506	ankyrin binding	1/4868	19/18639	0.0526315789473684	0.20152013147083	0.99683112595962	1
GO:0043395	heparan sulfate proteoglycan binding	1/4868	19/18639	0.0526315789473684	0.20152013147083	0.99683112595962	1
GO:0005126	cytokine receptor binding	53/4868	275/18639	0.192727272727273	0.737930081422275	0.997017800612748	1
GO:0001614	purinergic nucleotide receptor activity	1/4868	20/18639	0.05	0.191444124897288	0.997659594210349	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/4868	20/18639	0.05	0.191444124897288	0.997659594210349	1
GO:0016502	nucleotide receptor activity	1/4868	20/18639	0.05	0.191444124897288	0.997659594210349	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/4868	20/18639	0.05	0.191444124897288	0.997659594210349	1
GO:0008146	sulfotransferase activity	6/4868	53/18639	0.113207547169811	0.433458395993861	0.99769192224986	1
GO:0008527	taste receptor activity	2/4868	28/18639	0.0714285714285714	0.273491606996126	0.997739521458536	1
GO:0045499	chemorepellent activity	2/4868	28/18639	0.0714285714285714	0.273491606996126	0.997739521458536	1
GO:0005343	organic acid:sodium symporter activity	3/4868	35/18639	0.0857142857142857	0.328189928395352	0.997816882032809	1
GO:0001786	phosphatidylserine binding	7/4868	59/18639	0.11864406779661	0.454274194671532	0.99784628958407	1
GO:0038024	cargo receptor activity	8/4868	65/18639	0.123076923076923	0.471247076670248	0.998031595347765	1
GO:0015171	amino acid transmembrane transporter activity	15/4868	102/18639	0.147058823529412	0.56307095558026	0.998136695214884	1
GO:0004181	metallocarboxypeptidase activity	2/4868	29/18639	0.0689655172413793	0.264060861927294	0.998276516673262	1
GO:0004190	aspartic-type endopeptidase activity	3/4868	36/18639	0.0833333333333333	0.319073541495481	0.998301022964729	1
GO:0005253	monoatomic anion channel activity	15/4868	103/18639	0.145631067961165	0.557604247273656	0.998419945625362	1
GO:0098632	cell-cell adhesion mediator activity	6/4868	55/18639	0.109090909090909	0.417696272503175	0.998494441595538	1
GO:0015026	coreceptor activity	7/4868	61/18639	0.114754098360656	0.439379958780662	0.998572562166936	1
GO:0042805	actinin binding	3/4868	37/18639	0.0810810810810811	0.310449932265873	0.99867958400077	1
GO:0070001	aspartic-type peptidase activity	3/4868	37/18639	0.0810810810810811	0.310449932265873	0.99867958400077	1
GO:0001968	fibronectin binding	2/4868	30/18639	0.0666666666666667	0.255258833196385	0.998687266279282	1
GO:0033691	sialic acid binding	1/4868	22/18639	0.0454545454545455	0.174040113542989	0.998723447248234	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/4868	23/18639	0.0434782608695652	0.166473152084599	0.999057242102164	1
GO:0016917	GABA receptor activity	1/4868	23/18639	0.0434782608695652	0.166473152084599	0.999057242102164	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/4868	23/18639	0.0434782608695652	0.166473152084599	0.999057242102164	1
GO:0008009	chemokine activity	4/4868	45/18639	0.0888888888888889	0.340345110928513	0.999077714117038	1
GO:0072341	modified amino acid binding	12/4868	91/18639	0.131868131868132	0.504907582146695	0.999146992680137	1
GO:0046906	tetrapyrrole binding	24/4868	152/18639	0.157894736842105	0.60456039441249	0.999195559834264	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/4868	24/18639	0.0416666666666667	0.15953677074774	0.999303769038491	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/4868	24/18639	0.0416666666666667	0.15953677074774	0.999303769038491	1
GO:0003730	mRNA 3'-UTR binding	47/4868	262/18639	0.179389312977099	0.686860600776531	0.999361838125113	1
GO:0042923	neuropeptide binding	2/4868	33/18639	0.0606060606060606	0.232053484723986	0.999423088948185	1
GO:0001540	amyloid-beta binding	10/4868	83/18639	0.120481927710843	0.461311144330815	0.999499091447977	1
GO:0004222	metalloendopeptidase activity	15/4868	110/18639	0.136363636363636	0.522120340628968	0.999519504593574	1
GO:0019825	oxygen binding	2/4868	34/18639	0.0588235294117647	0.225228382232104	0.999562109034251	1
GO:0004175	endopeptidase activity	78/4868	405/18639	0.192592592592593	0.737414407011778	0.999566694929807	1
GO:0020037	heme binding	21/4868	142/18639	0.147887323943662	0.566243186315923	0.999615543798187	1
GO:0015291	secondary active transmembrane transporter activity	51/4868	287/18639	0.177700348432056	0.680393753990363	0.99970842603408	1
GO:0005245	voltage-gated calcium channel activity	3/4868	43/18639	0.0697674418604651	0.267131337065984	0.999716218331753	1
GO:0005104	fibroblast growth factor receptor binding	1/4868	27/18639	0.037037037037037	0.14181046288688	0.99971960954752	1
GO:0048020	CCR chemokine receptor binding	4/4868	50/18639	0.08	0.306310599835662	0.999726425762508	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	2/4868	36/18639	0.0555555555555556	0.21271569433032	0.999748283744315	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	3/4868	44/18639	0.0681818181818182	0.261060170314484	0.999781176719633	1
GO:0005010	insulin-like growth factor receptor activity	4/4868	51/18639	0.0784313725490196	0.300304509642805	0.999786205271083	1
GO:0005030	neurotrophin receptor activity	4/4868	51/18639	0.0784313725490196	0.300304509642805	0.999786205271083	1
GO:0051393	alpha-actinin binding	1/4868	28/18639	0.0357142857142857	0.136745803498063	0.999792946143408	1
GO:0098631	cell adhesion mediator activity	8/4868	76/18639	0.105263157894737	0.40304026294166	0.999794378311175	1
GO:0030280	structural constituent of skin epidermis	2/4868	37/18639	0.0540540540540541	0.206966621510582	0.999809352301089	1
GO:0043394	proteoglycan binding	2/4868	37/18639	0.0540540540540541	0.206966621510582	0.999809352301089	1
GO:0015085	calcium ion transmembrane transporter activity	21/4868	147/18639	0.142857142857143	0.546983213992253	0.999828295644336	1
GO:0015459	potassium channel regulator activity	5/4868	59/18639	0.0847457627118644	0.324481567622523	0.999848783467679	1
GO:0016247	channel regulator activity	25/4868	168/18639	0.148809523809524	0.56977418124193	0.999849474972466	1
GO:0042379	chemokine receptor binding	7/4868	72/18639	0.0972222222222222	0.372252465078061	0.999865592199424	1
GO:0005003	ephrin receptor activity	4/4868	53/18639	0.0754716981132075	0.288972263995907	0.999869843718987	1
GO:0005005	transmembrane-ephrin receptor activity	4/4868	53/18639	0.0754716981132075	0.288972263995907	0.999869843718987	1
GO:0017046	peptide hormone binding	4/4868	53/18639	0.0754716981132075	0.288972263995907	0.999869843718987	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	3/4868	46/18639	0.0652173913043478	0.249709728126898	0.999870250089977	1
GO:0008509	monoatomic anion transmembrane transporter activity	21/4868	149/18639	0.140939597315436	0.539641157428598	0.99987647855874	1
GO:0019955	cytokine binding	20/4868	144/18639	0.138888888888889	0.531789235825801	0.999879335928036	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	5/4868	60/18639	0.0833333333333333	0.319073541495481	0.999880855627315	1
GO:0048019	receptor antagonist activity	1/4868	30/18639	0.0333333333333333	0.127629416598192	0.999887098754615	1
GO:0098918	structural constituent of synapse	1/4868	30/18639	0.0333333333333333	0.127629416598192	0.999887098754615	1
GO:0141108	transporter regulator activity	25/4868	170/18639	0.147058823529412	0.56307095558026	0.999889971163855	1
GO:0015293	symporter activity	20/4868	146/18639	0.136986301369863	0.524504451773393	0.999913977058008	1
GO:0061134	peptidase regulator activity	36/4868	226/18639	0.15929203539823	0.609910486398441	0.999916506778473	1
GO:0005262	calcium channel activity	17/4868	131/18639	0.129770992366412	0.49687788141281	0.99992449713963	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	4/4868	56/18639	0.0714285714285714	0.273491606996126	0.999938629215184	1
GO:0005004	GPI-linked ephrin receptor activity	3/4868	49/18639	0.0612244897959184	0.234421377425251	0.999941136308821	1
GO:0005008	hepatocyte growth factor receptor activity	3/4868	49/18639	0.0612244897959184	0.234421377425251	0.999941136308821	1
GO:0005009	insulin receptor activity	3/4868	49/18639	0.0612244897959184	0.234421377425251	0.999941136308821	1
GO:0005011	macrophage colony-stimulating factor receptor activity	3/4868	49/18639	0.0612244897959184	0.234421377425251	0.999941136308821	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	3/4868	49/18639	0.0612244897959184	0.234421377425251	0.999941136308821	1
GO:0005020	stem cell factor receptor activity	3/4868	49/18639	0.0612244897959184	0.234421377425251	0.999941136308821	1
GO:0008288	boss receptor activity	3/4868	49/18639	0.0612244897959184	0.234421377425251	0.999941136308821	1
GO:0036332	placental growth factor receptor activity	3/4868	49/18639	0.0612244897959184	0.234421377425251	0.999941136308821	1
GO:0038062	protein tyrosine kinase collagen receptor activity	3/4868	49/18639	0.0612244897959184	0.234421377425251	0.999941136308821	1
GO:0060175	brain-derived neurotrophic factor receptor activity	3/4868	49/18639	0.0612244897959184	0.234421377425251	0.999941136308821	1
GO:0042562	hormone binding	10/4868	94/18639	0.106382978723404	0.40732792531338	0.999945688080232	1
GO:0008307	structural constituent of muscle	2/4868	42/18639	0.0476190476190476	0.182327737997418	0.999952918230535	1
GO:0042056	chemoattractant activity	2/4868	42/18639	0.0476190476190476	0.182327737997418	0.999952918230535	1
GO:0099106	ion channel regulator activity	22/4868	160/18639	0.1375	0.526471343467543	0.99995355298643	1
GO:0005254	chloride channel activity	8/4868	83/18639	0.0963855421686747	0.369048915464652	0.999954810284547	1
GO:0005006	epidermal growth factor receptor activity	3/4868	50/18639	0.06	0.229732949876746	0.999954841237308	1
GO:0005007	fibroblast growth factor receptor activity	3/4868	50/18639	0.06	0.229732949876746	0.999954841237308	1
GO:0005017	platelet-derived growth factor receptor activity	3/4868	50/18639	0.06	0.229732949876746	0.999954841237308	1
GO:0005019	platelet-derived growth factor beta-receptor activity	3/4868	50/18639	0.06	0.229732949876746	0.999954841237308	1
GO:0140375	immune receptor activity	21/4868	156/18639	0.134615384615385	0.515426490108084	0.999962127138127	1
GO:0004896	cytokine receptor activity	10/4868	96/18639	0.104166666666667	0.398841926869351	0.999964246904545	1
GO:0019199	transmembrane receptor protein kinase activity	7/4868	78/18639	0.0897435897435897	0.343617660072056	0.999965122676873	1
GO:0005021	vascular endothelial growth factor receptor activity	3/4868	51/18639	0.0588235294117647	0.225228382232104	0.999965380985198	1
GO:0005518	collagen binding	6/4868	72/18639	0.0833333333333333	0.319073541495481	0.999967856822929	1
GO:0015370	solute:sodium symporter activity	7/4868	79/18639	0.0886075949367089	0.339268069438233	0.999972243519602	1
GO:0030547	signaling receptor inhibitor activity	2/4868	44/18639	0.0454545454545455	0.174040113542989	0.999973192559796	1
GO:0015294	solute:monoatomic cation symporter activity	13/4868	116/18639	0.112068965517241	0.429098900631853	0.999979575921222	1
GO:0038064	collagen receptor activity	3/4868	53/18639	0.0566037735849057	0.21672919799693	0.999979697950042	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	3/4868	53/18639	0.0566037735849057	0.21672919799693	0.999979697950042	1
GO:0015103	inorganic anion transmembrane transporter activity	22/4868	165/18639	0.133333333333333	0.510517666392769	0.999980225891468	1
GO:0030246	carbohydrate binding	45/4868	280/18639	0.160714285714286	0.615356115741284	0.999980979178092	1
GO:0099095	ligand-gated monoatomic anion channel activity	2/4868	47/18639	0.0425531914893617	0.162931170125352	0.999988522939258	1
GO:0015108	chloride transmembrane transporter activity	13/4868	121/18639	0.107438016528926	0.411367541101612	0.999992546464565	1
GO:0005178	integrin binding	20/4868	161/18639	0.124223602484472	0.475637577384567	0.999993932687212	1
GO:0071855	neuropeptide receptor binding	1/4868	40/18639	0.025	0.0957220624486442	0.999994563998515	1
GO:0004497	monooxygenase activity	10/4868	106/18639	0.0943396226415094	0.361215329994884	0.999995821096893	1
GO:0008227	G protein-coupled amine receptor activity	1/4868	41/18639	0.024390243902439	0.0933873779986773	0.999995986787656	1
GO:0098960	postsynaptic neurotransmitter receptor activity	4/4868	69/18639	0.0579710144927536	0.221964202779465	0.999997830518897	1
GO:0022824	transmitter-gated monoatomic ion channel activity	3/4868	63/18639	0.0476190476190476	0.182327737997418	0.999998642531196	1
GO:0022835	transmitter-gated channel activity	3/4868	63/18639	0.0476190476190476	0.182327737997418	0.999998642531196	1
GO:0019838	growth factor binding	14/4868	136/18639	0.102941176470588	0.394149668906182	0.999998874331949	1
GO:0008188	neuropeptide receptor activity	1/4868	48/18639	0.0208333333333333	0.0797683853738702	0.999999520544526	1
GO:0016500	protein-hormone receptor activity	3/4868	67/18639	0.0447761194029851	0.171442499908019	0.999999546561991	1
GO:0061135	endopeptidase regulator activity	21/4868	184/18639	0.114130434782609	0.436992024222071	0.999999774743644	1
GO:0005272	sodium channel activity	1/4868	51/18639	0.0196078431372549	0.0750761274107013	0.999999807175437	1
GO:1901681	sulfur compound binding	37/4868	275/18639	0.134545454545455	0.515158736087249	0.999999911001254	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/4868	73/18639	0.0410958904109589	0.157351335532018	0.999999913572198	1
GO:0003823	antigen binding	18/4868	174/18639	0.103448275862069	0.396091292890942	0.999999945078043	1
GO:0008083	growth factor activity	15/4868	162/18639	0.0925925925925926	0.354526157217201	0.999999983991975	1
GO:0001664	G protein-coupled receptor binding	39/4868	297/18639	0.131313131313131	0.502782550235303	0.999999987504305	1
GO:0004867	serine-type endopeptidase inhibitor activity	4/4868	95/18639	0.0421052631578947	0.161216105176664	0.99999999796078	1
GO:0004866	endopeptidase inhibitor activity	13/4868	161/18639	0.0807453416149068	0.309164425299969	0.999999998773785	1
GO:0030594	neurotransmitter receptor activity	4/4868	97/18639	0.0412371134020619	0.15789206177096	0.999999998820402	1
GO:0001653	peptide receptor activity	8/4868	128/18639	0.0625	0.239305156121611	0.99999999895266	1
GO:0030414	peptidase inhibitor activity	14/4868	169/18639	0.0828402366863905	0.317185532374206	0.999999999150523	1
GO:0015081	sodium ion transmembrane transporter activity	13/4868	164/18639	0.0792682926829268	0.303508978495701	0.999999999385388	1
GO:0005179	hormone activity	8/4868	132/18639	0.0606060606060606	0.232053484723986	0.999999999616177	1
GO:0017171	serine hydrolase activity	18/4868	198/18639	0.0909090909090909	0.348080227085979	0.999999999656713	1
GO:0015079	potassium ion transmembrane transporter activity	12/4868	160/18639	0.075	0.287166187345933	0.999999999660174	1
GO:0008236	serine-type peptidase activity	17/4868	194/18639	0.0876288659793814	0.335520631263289	0.999999999786346	1
GO:0004252	serine-type endopeptidase activity	14/4868	176/18639	0.0795454545454545	0.304570198700232	0.999999999828587	1
GO:0099094	ligand-gated monoatomic cation channel activity	8/4868	136/18639	0.0588235294117647	0.225228382232104	0.999999999860274	1
GO:0005244	voltage-gated monoatomic ion channel activity	13/4868	173/18639	0.0751445086705202	0.287719494065289	0.999999999924514	1
GO:0022832	voltage-gated channel activity	13/4868	175/18639	0.0742857142857143	0.284431271275971	0.99999999995286	1
GO:0008528	G protein-coupled peptide receptor activity	5/4868	122/18639	0.040983606557377	0.156921413850236	0.99999999998756	1
GO:0005249	voltage-gated potassium channel activity	2/4868	98/18639	0.0204081632653061	0.0781404591417504	0.999999999995706	1
GO:0005125	cytokine activity	20/4868	234/18639	0.0854700854700855	0.327254914354339	0.999999999998114	1
GO:0005267	potassium channel activity	4/4868	124/18639	0.032258064516129	0.123512338643412	0.999999999999348	1
GO:0022834	ligand-gated channel activity	12/4868	188/18639	0.0638297872340425	0.244396755188028	0.999999999999605	1
GO:0022843	voltage-gated monoatomic cation channel activity	6/4868	143/18639	0.041958041958042	0.160652412501221	0.999999999999609	1
GO:0015276	ligand-gated monoatomic ion channel activity	11/4868	186/18639	0.0591397849462366	0.226439287512922	0.999999999999889	1
GO:0005549	odorant binding	1/4868	111/18639	0.00900900900900901	0.0344944369184303	0.999999999999998	1
GO:0046873	metal ion transmembrane transporter activity	50/4868	450/18639	0.111111111111111	0.425431388660641	1	1
GO:0008201	heparin binding	6/4868	172/18639	0.0348837209302326	0.133565668532992	1	1
GO:0005261	monoatomic cation channel activity	30/4868	341/18639	0.0879765395894428	0.336851832663851	1	1
GO:0004984	olfactory receptor activity	2/4868	419/18639	0.00477326968973747	0.0182762887730108	1	1
GO:0005201	extracellular matrix structural constituent	4/4868	168/18639	0.0238095238095238	0.0911638689987088	1	1
GO:0005216	monoatomic ion channel activity	46/4868	448/18639	0.102678571428571	0.393144185056932	1	1
GO:0005539	glycosaminoglycan binding	12/4868	242/18639	0.0495867768595041	0.189861942046898	1	1
GO:0022836	gated channel activity	23/4868	318/18639	0.0723270440251572	0.276931752996078	1	1
GO:0030371	translation repressor activity	11/4868	329/18639	0.033434650455927	0.128017347955634	1	1
GO:0045182	translation regulator activity	14/4868	356/18639	0.0393258426966292	0.150574030818092	1	1