ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	44/1583	175/18639	0.251428571428571	2.96044039346629	3.43523113724611e-11	3.82684748689216e-08
GO:0051082	unfolded protein binding	33/1583	121/18639	0.272727272727273	3.21122150117728	1.02256745603171e-09	3.88343907907463e-07
GO:0051537	2 iron, 2 sulfur cluster binding	15/1583	28/18639	0.535714285714286	6.30775652016966	1.0458094467885e-09	3.88343907907463e-07
GO:0140662	ATP-dependent protein folding chaperone	17/1583	40/18639	0.425	5.00415350600126	7.64541991676055e-09	2.12924944681781e-06
GO:0009055	electron transfer activity	29/1583	116/18639	0.25	2.94361970941251	8.50022522473222e-08	1.89385018007034e-05
GO:0031625	ubiquitin protein ligase binding	54/1583	302/18639	0.178807947019868	2.10537038818908	1.21446705732392e-07	2.25486050309808e-05
GO:0005525	GTP binding	63/1583	378/18639	0.166666666666667	1.96241313960834	1.61552467610542e-07	2.57099212740206e-05
GO:0044389	ubiquitin-like protein ligase binding	56/1583	322/18639	0.173913043478261	2.04773545002609	1.86647948428608e-07	2.59907268186837e-05
GO:0044183	protein folding chaperone	21/1583	75/18639	0.28	3.29685407454201	6.77592995896619e-07	8.38709552698704e-05
GO:0016853	isomerase activity	36/1583	180/18639	0.2	2.35489576753001	1.02372146081835e-06	0.00010290575590465
GO:0008135	translation factor activity, RNA binding	22/1583	83/18639	0.265060240963855	3.12094619793133	1.03691634780948e-06	0.00010290575590465
GO:0019001	guanyl nucleotide binding	63/1583	400/18639	0.1575	1.85448041692988	1.22507197437401e-06	0.00010290575590465
GO:0032561	guanyl ribonucleotide binding	63/1583	400/18639	0.1575	1.85448041692988	1.22507197437401e-06	0.00010290575590465
GO:0180051	translation factor activity	22/1583	84/18639	0.261904761904762	3.08379207652739	1.29325007420566e-06	0.00010290575590465
GO:0015036	disulfide oxidoreductase activity	14/1583	40/18639	0.35	4.12106759317751	2.68670146163208e-06	0.000199532361883876
GO:0019003	GDP binding	20/1583	75/18639	0.266666666666667	3.13986102337334	2.86799937081273e-06	0.000199684456192836
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	16/1583	54/18639	0.296296296296296	3.48873447041482	6.37817621116449e-06	0.000417958135249249
GO:0003756	protein disulfide isomerase activity	9/1583	19/18639	0.473684210526316	5.57738471257107	9.45975755981376e-06	0.000554640522191186
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	9/1583	19/18639	0.473684210526316	5.57738471257107	9.45975755981376e-06	0.000554640522191186
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	18/1583	68/18639	0.264705882352941	3.11677380996618	9.95832799763337e-06	0.000554678869468179
GO:0043021	ribonucleoprotein complex binding	33/1583	177/18639	0.186440677966102	2.19524181718899	1.35766487615641e-05	0.000707256608870072
GO:0051536	iron-sulfur cluster binding	19/1583	76/18639	0.25	2.94361970941251	1.3967365704795e-05	0.000707256608870072
GO:0051540	metal cluster binding	19/1583	77/18639	0.246753246753247	2.90539088201754	1.7082102095267e-05	0.000827367901483801
GO:0061650	ubiquitin-like protein conjugating enzyme activity	13/1583	41/18639	0.317073170731707	3.73337133876708	2.08437931822636e-05	0.000942500824759198
GO:0003924	GTPase activity	51/1583	331/18639	0.154078549848943	1.81419462453218	2.27380731829097e-05	0.000942500824759198
GO:0016860	intramolecular oxidoreductase activity	15/1583	53/18639	0.283018867924528	3.33239967103303	2.27502938679833e-05	0.000942500824759198
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	12/1583	36/18639	0.333333333333333	3.92482627921668	2.45354792800868e-05	0.000942500824759198
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	12/1583	36/18639	0.333333333333333	3.92482627921668	2.45354792800868e-05	0.000942500824759198
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	12/1583	36/18639	0.333333333333333	3.92482627921668	2.45354792800868e-05	0.000942500824759198
GO:0003954	NADH dehydrogenase activity	13/1583	44/18639	0.295454545454545	3.47882329294205	4.82540716055303e-05	0.00179183452561869
GO:0003746	translation elongation factor activity	8/1583	18/18639	0.444444444444444	5.23310170562224	5.35573906906393e-05	0.00192461074933459
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	12/1583	39/18639	0.307692307692308	3.62291656543078	6.03124634639851e-05	0.00209962763433998
GO:0015035	protein-disulfide reductase activity	11/1583	34/18639	0.323529411764706	3.80939021218089	7.30276800682754e-05	0.00246523744230481
GO:0008137	NADH dehydrogenase (ubiquinone) activity	12/1583	41/18639	0.292682926829268	3.44618892809269	0.000103840525477838	0.00340230427595033
GO:0003925	G protein activity	14/1583	54/18639	0.259259259259259	3.05264266161297	0.000121246075828019	0.00385908938492608
GO:0016859	cis-trans isomerase activity	12/1583	42/18639	0.285714285714286	3.36413681075715	0.000134234876715534	0.0041538236850307
GO:0003743	translation initiation factor activity	13/1583	51/18639	0.254901960784314	3.0013377429304	0.000252590491887814	0.00760502183683852
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	14/1583	58/18639	0.241379310344828	2.84211558150173	0.000274713944027943	0.00805345614860864
GO:0051787	misfolded protein binding	7/1583	17/18639	0.411764705882353	4.84831481550295	0.000285125926090838	0.00814436619654341
GO:0061631	ubiquitin conjugating enzyme activity	10/1583	35/18639	0.285714285714286	3.36413681075715	0.000482641880327075	0.0134415763671091
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	12/1583	48/18639	0.25	2.94361970941251	0.000524739318933841	0.0142575512510317
GO:0031072	heat shock protein binding	23/1583	131/18639	0.175572519083969	2.0672749104271	0.00063605675264088	0.0168706481533795
GO:0051087	protein-folding chaperone binding	23/1583	134/18639	0.171641791044776	2.02099263631307	0.000879089029428219	0.022774539041466
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	22/1583	128/18639	0.171875	2.0237385502211	0.00110491030475795	0.0278064602226127
GO:0043022	ribosome binding	20/1583	112/18639	0.178571428571429	2.10258550672322	0.00112324121186497	0.0278064602226127
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	5/1583	11/18639	0.454545454545455	5.35203583529547	0.00131157420252858	0.0317629056873227
GO:0015399	primary active transmembrane transporter activity	26/1583	166/18639	0.156626506024096	1.84419548059579	0.00169614414926726	0.037419194937611
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	7/1583	22/18639	0.318181818181818	3.74642508470683	0.00171308702138075	0.037419194937611
GO:0034062	5'-3' RNA polymerase activity	7/1583	22/18639	0.318181818181818	3.74642508470683	0.00171308702138075	0.037419194937611
GO:0097747	RNA polymerase activity	7/1583	22/18639	0.318181818181818	3.74642508470683	0.00171308702138075	0.037419194937611
GO:0140517	protein-RNA adaptor activity	7/1583	22/18639	0.318181818181818	3.74642508470683	0.00171308702138075	0.037419194937611
GO:0140098	catalytic activity, acting on RNA	50/1583	387/18639	0.129198966408269	1.52125049582042	0.00188397415497068	0.0403605232430257
GO:0016018	cyclosporin A binding	6/1583	17/18639	0.352941176470588	4.15569841328825	0.0020252472648559	0.0425684047745182
GO:0022853	active monoatomic ion transmembrane transporter activity	20/1583	118/18639	0.169491525423729	1.99567437926272	0.00215842359523754	0.0443776321332351
GO:0016209	antioxidant activity	16/1583	86/18639	0.186046511627907	2.1906007139814	0.00219099620047391	0.0443776321332351
GO:0000049	tRNA binding	15/1583	80/18639	0.1875	2.20771478205938	0.00274455527542528	0.0545970460147101
GO:0035925	mRNA 3'-UTR AU-rich region binding	8/1583	30/18639	0.266666666666667	3.13986102337334	0.00285157911614982	0.0557308620244018
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	20/1583	122/18639	0.163934426229508	1.93024243240164	0.00322441457802877	0.0619309972400698
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	21/1583	132/18639	0.159090909090909	1.87321254235341	0.00372797188632623	0.0703891640909732
GO:0051059	NF-kappaB binding	8/1583	32/18639	0.25	2.94361970941251	0.00440139718733889	0.0817192744449254
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	12/1583	61/18639	0.19672131147541	2.31629091888197	0.00469954125125429	0.0858244090802833
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	6/1583	20/18639	0.3	3.53234365129501	0.0050846682992737	0.0913600078288856
GO:0002020	protease binding	21/1583	136/18639	0.154411764705882	1.81811805581361	0.00531391254798953	0.0922937196873305
GO:0071889	14-3-3 protein binding	8/1583	33/18639	0.242424242424242	2.85441911215758	0.00538518113076883	0.0922937196873305
GO:0140416	transcription regulator inhibitor activity	8/1583	33/18639	0.242424242424242	2.85441911215758	0.00538518113076883	0.0922937196873305
GO:0032182	ubiquitin-like protein binding	19/1583	120/18639	0.158333333333333	1.86429248262792	0.00592593243636611	0.100022556577452
GO:0004364	glutathione transferase activity	7/1583	27/18639	0.259259259259259	3.05264266161297	0.00612974549108105	0.101918454881557
GO:0140693	molecular condensate scaffold activity	10/1583	48/18639	0.208333333333333	2.45301642451042	0.00625063984036117	0.102400187972976
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	5/1583	15/18639	0.333333333333333	3.92482627921668	0.0063941593238038	0.103233238937934
GO:0008641	ubiquitin-like modifier activating enzyme activity	4/1583	10/18639	0.4	4.70979153506001	0.00716937009617431	0.112488426579411
GO:0141109	transporter activator activity	4/1583	10/18639	0.4	4.70979153506001	0.00716937009617431	0.112488426579411
GO:0015078	proton transmembrane transporter activity	26/1583	185/18639	0.140540540540541	1.65479162042649	0.00747786487848337	0.115699187147645
GO:0004601	peroxidase activity	11/1583	57/18639	0.192982456140351	2.27226784586229	0.00772247926648626	0.117847149354325
GO:0043023	ribosomal large subunit binding	5/1583	16/18639	0.3125	3.67952463676563	0.00865919229264617	0.130355948837944
GO:0030544	Hsp70 protein binding	10/1583	51/18639	0.196078431372549	2.30872134071569	0.00968682803213367	0.1426740351189
GO:0043130	ubiquitin binding	16/1583	100/18639	0.16	1.88391661402401	0.00995374447256673	0.1426740351189
GO:0003725	double-stranded RNA binding	13/1583	75/18639	0.173333333333333	2.04090966519267	0.0100053678299813	0.1426740351189
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	11/1583	59/18639	0.186440677966102	2.19524181718899	0.010027536331848	0.1426740351189
GO:0016790	thiolester hydrolase activity	9/1583	44/18639	0.204545454545455	2.40841612588296	0.0104778964406785	0.1426740351189
GO:0010854	adenylate cyclase regulator activity	4/1583	11/18639	0.363636363636364	4.28162866823638	0.0105166820354004	0.1426740351189
GO:0019206	nucleoside kinase activity	4/1583	11/18639	0.363636363636364	4.28162866823638	0.0105166820354004	0.1426740351189
GO:0048407	platelet-derived growth factor binding	4/1583	11/18639	0.363636363636364	4.28162866823638	0.0105166820354004	0.1426740351189
GO:0140103	catalytic activity, acting on a glycoprotein	6/1583	23/18639	0.260869565217391	3.07160317503914	0.010630112131839	0.1426740351189
GO:0005506	iron ion binding	22/1583	154/18639	0.142857142857143	1.68206840537858	0.0109399362413016	0.143501963372484
GO:0016829	lyase activity	27/1583	200/18639	0.135	1.58955464308275	0.0109494316756384	0.143501963372484
GO:0004029	aldehyde dehydrogenase (NAD+) activity	5/1583	17/18639	0.294117647058824	3.46308201107354	0.0114233360542255	0.146271222579393
GO:0004549	tRNA-specific ribonuclease activity	5/1583	17/18639	0.294117647058824	3.46308201107354	0.0114233360542255	0.146271222579393
GO:0000287	magnesium ion binding	30/1583	230/18639	0.130434782608696	1.53580158751957	0.012166241599752	0.154013558433225
GO:0016251	RNA polymerase II general transcription initiation factor activity	10/1583	53/18639	0.188679245283019	2.22159978068869	0.0126732311474287	0.158628983126242
GO:0140101	catalytic activity, acting on a tRNA	20/1583	139/18639	0.143884892086331	1.69416961692806	0.0137149261949113	0.169760308679235
GO:0004300	enoyl-CoA hydratase activity	4/1583	12/18639	0.333333333333333	3.92482627921668	0.0147291010670365	0.170948935869716
GO:0004859	phospholipase inhibitor activity	4/1583	12/18639	0.333333333333333	3.92482627921668	0.0147291010670365	0.170948935869716
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/1583	12/18639	0.333333333333333	3.92482627921668	0.0147291010670365	0.170948935869716
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	5/1583	18/18639	0.277777777777778	3.2706885660139	0.0147316856763848	0.170948935869716
GO:0031690	adrenergic receptor binding	5/1583	18/18639	0.277777777777778	3.2706885660139	0.0147316856763848	0.170948935869716
GO:1990381	ubiquitin-specific protease binding	5/1583	18/18639	0.277777777777778	3.2706885660139	0.0147316856763848	0.170948935869716
GO:0016651	oxidoreductase activity, acting on NAD(P)H	14/1583	88/18639	0.159090909090909	1.87321254235341	0.0160171882481844	0.183246781558136
GO:0047617	fatty acyl-CoA hydrolase activity	6/1583	25/18639	0.24	2.82587492103601	0.0161204529557426	0.183246781558136
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	5/1583	19/18639	0.263157894736842	3.09854706253948	0.0186248157330348	0.209576209359604
GO:0008198	ferrous iron binding	6/1583	26/18639	0.230769230769231	2.71718742407308	0.0194886500354765	0.212846628818832
GO:0016289	acyl-CoA hydrolase activity	6/1583	26/18639	0.230769230769231	2.71718742407308	0.0194886500354765	0.212846628818832
GO:0097602	cullin family protein binding	6/1583	26/18639	0.230769230769231	2.71718742407308	0.0194886500354765	0.212846628818832
GO:0160215	deacylase activity	11/1583	65/18639	0.169230769230769	1.99260411098693	0.0201570441365629	0.215099545352664
GO:0016877	ligase activity, forming carbon-sulfur bonds	8/1583	41/18639	0.195121951219512	2.29745928539513	0.0202741941310859	0.215099545352664
GO:0140318	protein transporter activity	8/1583	41/18639	0.195121951219512	2.29745928539513	0.0202741941310859	0.215099545352664
GO:0004860	protein kinase inhibitor activity	13/1583	84/18639	0.154761904761905	1.82224077249346	0.0244471293993978	0.256925491989898
GO:0016229	steroid dehydrogenase activity	7/1583	35/18639	0.2	2.35489576753001	0.0256394364335626	0.260792605184991
GO:0070063	RNA polymerase binding	10/1583	59/18639	0.169491525423729	1.99567437926272	0.025788345868456	0.260792605184991
GO:0008191	metalloendopeptidase inhibitor activity	4/1583	14/18639	0.285714285714286	3.36413681075715	0.0259856186494919	0.260792605184991
GO:0008474	palmitoyl-(protein) hydrolase activity	4/1583	14/18639	0.285714285714286	3.36413681075715	0.0259856186494919	0.260792605184991
GO:0098599	palmitoyl hydrolase activity	4/1583	14/18639	0.285714285714286	3.36413681075715	0.0259856186494919	0.260792605184991
GO:0045296	cadherin binding	39/1583	334/18639	0.116766467065868	1.37486429541423	0.0262426324842538	0.261020469530882
GO:0019887	protein kinase regulator activity	31/1583	255/18639	0.12156862745098	1.43140723124373	0.0271606339074111	0.267760585600496
GO:0046966	nuclear thyroid hormone receptor binding	6/1583	28/18639	0.214285714285714	2.52310260806786	0.0275928697966684	0.269635587311303
GO:0005123	death receptor binding	5/1583	21/18639	0.238095238095238	2.80344734229763	0.0283017778074857	0.274158091109036
GO:0019207	kinase regulator activity	34/1583	287/18639	0.118466898954704	1.39488599470418	0.0300500867126958	0.286138573114719
GO:0019205	nucleobase-containing compound kinase activity	8/1583	44/18639	0.181818181818182	2.14081433411819	0.0300522558836824	0.286138573114719
GO:0016836	hydro-lyase activity	10/1583	61/18639	0.163934426229508	1.93024243240164	0.0317807156573088	0.297454042291892
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	40/1583	349/18639	0.114613180515759	1.34951046849857	0.03196778785451	0.297454042291892
GO:0003785	actin monomer binding	6/1583	29/18639	0.206896551724138	2.43609906985863	0.0323700333335811	0.297454042291892
GO:0000774	adenyl-nucleotide exchange factor activity	4/1583	15/18639	0.266666666666667	3.13986102337334	0.0331097856770149	0.297454042291892
GO:0004559	alpha-mannosidase activity	4/1583	15/18639	0.266666666666667	3.13986102337334	0.0331097856770149	0.297454042291892
GO:0031386	protein tag activity	4/1583	15/18639	0.266666666666667	3.13986102337334	0.0331097856770149	0.297454042291892
GO:0141047	molecular tag activity	4/1583	15/18639	0.266666666666667	3.13986102337334	0.0331097856770149	0.297454042291892
GO:0016835	carbon-oxygen lyase activity	12/1583	79/18639	0.151898734177215	1.78852843103545	0.0339841920204554	0.302867119286298
GO:0016755	aminoacyltransferase activity	54/1583	496/18639	0.108870967741935	1.2818989057119	0.0350643295995549	0.31001319979289
GO:0017069	snRNA binding	9/1583	54/18639	0.166666666666667	1.96241313960834	0.0368407002916531	0.320629219725793
GO:0051287	NAD binding	9/1583	54/18639	0.166666666666667	1.96241313960834	0.0368407002916531	0.320629219725793
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	8/1583	46/18639	0.173913043478261	2.04773545002609	0.0381249137047132	0.328311582768502
GO:0005109	frizzled binding	7/1583	38/18639	0.184210526315789	2.16898294377764	0.0386053854497446	0.328311582768502
GO:0019210	kinase inhibitor activity	13/1583	90/18639	0.144444444444444	1.70075805432723	0.0402658068669167	0.328311582768502
GO:0004022	alcohol dehydrogenase (NAD+) activity	5/1583	23/18639	0.217391304347826	2.55966931253262	0.0406701326827309	0.328311582768502
GO:0004602	glutathione peroxidase activity	5/1583	23/18639	0.217391304347826	2.55966931253262	0.0406701326827309	0.328311582768502
GO:0008171	O-methyltransferase activity	5/1583	23/18639	0.217391304347826	2.55966931253262	0.0406701326827309	0.328311582768502
GO:0000062	fatty-acyl-CoA binding	4/1583	16/18639	0.25	2.94361970941251	0.0412599834718045	0.328311582768502
GO:0008142	oxysterol binding	4/1583	16/18639	0.25	2.94361970941251	0.0412599834718045	0.328311582768502
GO:0015923	mannosidase activity	4/1583	16/18639	0.25	2.94361970941251	0.0412599834718045	0.328311582768502
GO:0016722	oxidoreductase activity, acting on metal ions	4/1583	16/18639	0.25	2.94361970941251	0.0412599834718045	0.328311582768502
GO:0030275	LRR domain binding	4/1583	16/18639	0.25	2.94361970941251	0.0412599834718045	0.328311582768502
GO:0055102	lipase inhibitor activity	4/1583	16/18639	0.25	2.94361970941251	0.0412599834718045	0.328311582768502
GO:0019843	rRNA binding	10/1583	65/18639	0.153846153846154	1.81145828271539	0.0465670750520876	0.348673571738714
GO:0005522	profilin binding	3/1583	10/18639	0.3	3.53234365129501	0.0466358727011386	0.348673571738714
GO:0005528	FK506 binding	3/1583	10/18639	0.3	3.53234365129501	0.0466358727011386	0.348673571738714
GO:0015279	store-operated calcium channel activity	3/1583	10/18639	0.3	3.53234365129501	0.0466358727011386	0.348673571738714
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/1583	10/18639	0.3	3.53234365129501	0.0466358727011386	0.348673571738714
GO:0030957	Tat protein binding	3/1583	10/18639	0.3	3.53234365129501	0.0466358727011386	0.348673571738714
GO:0033204	ribonuclease P RNA binding	3/1583	10/18639	0.3	3.53234365129501	0.0466358727011386	0.348673571738714
GO:0047429	nucleoside triphosphate diphosphatase activity	3/1583	10/18639	0.3	3.53234365129501	0.0466358727011386	0.348673571738714
GO:0097177	mitochondrial ribosome binding	3/1583	10/18639	0.3	3.53234365129501	0.0466358727011386	0.348673571738714
GO:0048027	mRNA 5'-UTR binding	5/1583	24/18639	0.208333333333333	2.45301642451042	0.0479053048909346	0.353273685100857
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	7/1583	40/18639	0.175	2.06053379658876	0.0492776353805533	0.353273685100857
GO:0061791	GTPase motor activity	7/1583	40/18639	0.175	2.06053379658876	0.0492776353805533	0.353273685100857
GO:1990606	membrane scission GTPase motor activity	7/1583	40/18639	0.175	2.06053379658876	0.0492776353805533	0.353273685100857
GO:0008378	galactosyltransferase activity	6/1583	32/18639	0.1875	2.20771478205938	0.0497881225860274	0.353273685100857
GO:0022884	macromolecule transmembrane transporter activity	6/1583	32/18639	0.1875	2.20771478205938	0.0497881225860274	0.353273685100857
GO:0031369	translation initiation factor binding	6/1583	32/18639	0.1875	2.20771478205938	0.0497881225860274	0.353273685100857
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/1583	32/18639	0.1875	2.20771478205938	0.0497881225860274	0.353273685100857
GO:1901567	fatty acid derivative binding	4/1583	17/18639	0.235294117647059	2.77046560885883	0.0504404903695211	0.355637381466117
GO:0051117	ATPase binding	12/1583	84/18639	0.142857142857143	1.68206840537858	0.0510238690392119	0.357487988111208
GO:0016763	pentosyltransferase activity	8/1583	49/18639	0.163265306122449	1.92236389186123	0.0527567132313337	0.367318615873161
GO:0061980	regulatory RNA binding	9/1583	58/18639	0.155172413793103	1.82707430239397	0.054651879108726	0.377888157613432
GO:0019787	ubiquitin-like protein transferase activity	51/1583	479/18639	0.106471816283925	1.25365014764123	0.0549532150209838	0.377888157613432
GO:0019239	deaminase activity	6/1583	33/18639	0.181818181818182	2.14081433411819	0.0566568898092928	0.387213345077007
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	3/1583	11/18639	0.272727272727273	3.21122150117728	0.0601805692007904	0.395066132629769
GO:0015217	ADP transmembrane transporter activity	3/1583	11/18639	0.272727272727273	3.21122150117728	0.0601805692007904	0.395066132629769
GO:0034056	estrogen response element binding	3/1583	11/18639	0.272727272727273	3.21122150117728	0.0601805692007904	0.395066132629769
GO:0043522	leucine zipper domain binding	3/1583	11/18639	0.272727272727273	3.21122150117728	0.0601805692007904	0.395066132629769
GO:0070990	snRNP binding	3/1583	11/18639	0.272727272727273	3.21122150117728	0.0601805692007904	0.395066132629769
GO:1900750	oligopeptide binding	3/1583	11/18639	0.272727272727273	3.21122150117728	0.0601805692007904	0.395066132629769
GO:0140223	general transcription initiation factor activity	10/1583	68/18639	0.147058823529412	1.73154100553677	0.060295937233616	0.395066132629769
GO:0098641	cadherin binding involved in cell-cell adhesion	4/1583	18/18639	0.222222222222222	2.61655085281112	0.0606430059961315	0.395066132629769
GO:0048487	beta-tubulin binding	7/1583	42/18639	0.166666666666667	1.96241313960834	0.0616511257835066	0.396990486259112
GO:0051879	Hsp90 protein binding	7/1583	42/18639	0.166666666666667	1.96241313960834	0.0616511257835066	0.396990486259112
GO:0016831	carboxy-lyase activity	6/1583	34/18639	0.176470588235294	2.07784920664412	0.064066081587837	0.404675804317623
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	6/1583	34/18639	0.176470588235294	2.07784920664412	0.064066081587837	0.404675804317623
GO:0016830	carbon-carbon lyase activity	8/1583	51/18639	0.156862745098039	1.84697707257255	0.0642714597228872	0.404675804317623
GO:0003712	transcription coregulator activity	52/1583	495/18639	0.105050505050505	1.23691494860162	0.064297681655493	0.404675804317623
GO:0008080	N-acetyltransferase activity	10/1583	69/18639	0.144927536231884	1.70644620835508	0.0653988341502231	0.409293827209823
GO:0044325	transmembrane transporter binding	17/1583	136/18639	0.125	1.47180985470625	0.0689455932940585	0.429080396254643
GO:0016757	glycosyltransferase activity	30/1583	267/18639	0.112359550561798	1.32297515029776	0.0698478773324539	0.430352816700929
GO:0140297	DNA-binding transcription factor binding	51/1583	488/18639	0.104508196721311	1.23052955065605	0.0712216958967779	0.430352816700929
GO:0033218	amide binding	28/1583	247/18639	0.11336032388664	1.33475873463239	0.0712674781419049	0.430352816700929
GO:0050145	nucleoside monophosphate kinase activity	4/1583	19/18639	0.210526315789474	2.47883765003159	0.0718478567329572	0.430352816700929
GO:0070003	threonine-type peptidase activity	4/1583	19/18639	0.210526315789474	2.47883765003159	0.0718478567329572	0.430352816700929
GO:0120227	acyl-CoA binding	4/1583	19/18639	0.210526315789474	2.47883765003159	0.0718478567329572	0.430352816700929
GO:0008320	protein transmembrane transporter activity	5/1583	27/18639	0.185185185185185	2.18045904400927	0.073873858015619	0.430352816700929
GO:0048306	calcium-dependent protein binding	11/1583	80/18639	0.1375	1.61899084017688	0.0749494595842951	0.430352816700929
GO:0004526	ribonuclease P activity	3/1583	12/18639	0.25	2.94361970941251	0.0753310585787084	0.430352816700929
GO:0005527	macrolide binding	3/1583	12/18639	0.25	2.94361970941251	0.0753310585787084	0.430352816700929
GO:0031543	peptidyl-proline dioxygenase activity	3/1583	12/18639	0.25	2.94361970941251	0.0753310585787084	0.430352816700929
GO:0035197	siRNA binding	3/1583	12/18639	0.25	2.94361970941251	0.0753310585787084	0.430352816700929
GO:0035497	cAMP response element binding	3/1583	12/18639	0.25	2.94361970941251	0.0753310585787084	0.430352816700929
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	3/1583	12/18639	0.25	2.94361970941251	0.0753310585787084	0.430352816700929
GO:1990247	N6-methyladenosine-containing RNA reader activity	3/1583	12/18639	0.25	2.94361970941251	0.0753310585787084	0.430352816700929
GO:1990459	transferrin receptor binding	3/1583	12/18639	0.25	2.94361970941251	0.0753310585787084	0.430352816700929
GO:0004857	enzyme inhibitor activity	44/1583	416/18639	0.105769230769231	1.24537756936683	0.0763074348711083	0.433706543093952
GO:0016887	ATP hydrolysis activity	44/1583	417/18639	0.105515587529976	1.24239105241391	0.0785936525189708	0.4444331416555
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	4/1583	20/18639	0.2	2.35489576753001	0.0840252713634578	0.461104198516709
GO:0010851	cyclase regulator activity	4/1583	20/18639	0.2	2.35489576753001	0.0840252713634578	0.461104198516709
GO:0016004	phospholipase activator activity	4/1583	20/18639	0.2	2.35489576753001	0.0840252713634578	0.461104198516709
GO:0016408	C-acyltransferase activity	4/1583	20/18639	0.2	2.35489576753001	0.0840252713634578	0.461104198516709
GO:0030742	GTP-dependent protein binding	4/1583	20/18639	0.2	2.35489576753001	0.0840252713634578	0.461104198516709
GO:0043024	ribosomal small subunit binding	4/1583	20/18639	0.2	2.35489576753001	0.0840252713634578	0.461104198516709
GO:0004521	RNA endonuclease activity	10/1583	73/18639	0.136986301369863	1.6129423065274	0.0885103200987173	0.483335767597898
GO:0008238	exopeptidase activity	13/1583	102/18639	0.127450980392157	1.5006688714652	0.0909364074775042	0.494161745999706
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/1583	13/18639	0.230769230769231	2.71718742407308	0.0919695119480347	0.494947035314544
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/1583	13/18639	0.230769230769231	2.71718742407308	0.0919695119480347	0.494947035314544
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4/1583	21/18639	0.19047619047619	2.2427578738381	0.0971366816119217	0.520241650556158
GO:0003714	transcription corepressor activity	23/1583	204/18639	0.112745098039216	1.32751477091152	0.098998468362769	0.527676046680022
GO:0016410	N-acyltransferase activity	12/1583	94/18639	0.127659574468085	1.50312495799788	0.100523484329169	0.533253150203304
GO:0004842	ubiquitin-protein transferase activity	46/1583	449/18639	0.102449888641425	1.20629404572807	0.105485960729356	0.556925877973945
GO:0016776	phosphotransferase activity, phosphate group as acceptor	6/1583	39/18639	0.153846153846154	1.81145828271539	0.109138843791966	0.561931847712655
GO:0005161	platelet-derived growth factor receptor binding	3/1583	14/18639	0.214285714285714	2.52310260806786	0.109965119211274	0.561931847712655
GO:0005347	ATP transmembrane transporter activity	3/1583	14/18639	0.214285714285714	2.52310260806786	0.109965119211274	0.561931847712655
GO:0008392	arachidonate epoxygenase activity	3/1583	14/18639	0.214285714285714	2.52310260806786	0.109965119211274	0.561931847712655
GO:0016530	metallochaperone activity	3/1583	14/18639	0.214285714285714	2.52310260806786	0.109965119211274	0.561931847712655
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	3/1583	14/18639	0.214285714285714	2.52310260806786	0.109965119211274	0.561931847712655
GO:0070742	C2H2 zinc finger domain binding	3/1583	14/18639	0.214285714285714	2.52310260806786	0.109965119211274	0.561931847712655
GO:0140104	molecular carrier activity	27/1583	249/18639	0.108433734939759	1.27675071733555	0.112631897968278	0.57223708263676
GO:0016407	acetyltransferase activity	12/1583	96/18639	0.125	1.47180985470625	0.113009118653579	0.57223708263676
GO:0016779	nucleotidyltransferase activity	16/1583	136/18639	0.117647058823529	1.38523280442942	0.114234596297172	0.575825069117872
GO:0060590	ATPase regulator activity	7/1583	49/18639	0.142857142857143	1.68206840537858	0.11855445519314	0.594908392275484
GO:0032934	sterol binding	9/1583	68/18639	0.132352941176471	1.55838690498309	0.120502988465073	0.601974570179779
GO:0046982	protein heterodimerization activity	38/1583	369/18639	0.102981029810298	1.21254795618076	0.12404727542058	0.614980141840384
GO:0005212	structural constituent of eye lens	4/1583	23/18639	0.173913043478261	2.04773545002609	0.125970934347024	0.614980141840384
GO:0031681	G-protein beta-subunit binding	4/1583	23/18639	0.173913043478261	2.04773545002609	0.125970934347024	0.614980141840384
GO:0005496	steroid binding	13/1583	108/18639	0.12037037037037	1.41729837860602	0.126725413226508	0.614980141840384
GO:0015605	organophosphate ester transmembrane transporter activity	7/1583	50/18639	0.14	1.648427037271	0.128357649548904	0.614980141840384
GO:0004129	cytochrome-c oxidase activity	3/1583	15/18639	0.2	2.35489576753001	0.129178952594838	0.614980141840384
GO:0008242	omega peptidase activity	3/1583	15/18639	0.2	2.35489576753001	0.129178952594838	0.614980141840384
GO:0048531	beta-1,3-galactosyltransferase activity	3/1583	15/18639	0.2	2.35489576753001	0.129178952594838	0.614980141840384
GO:0050700	CARD domain binding	3/1583	15/18639	0.2	2.35489576753001	0.129178952594838	0.614980141840384
GO:0050780	dopamine receptor binding	3/1583	15/18639	0.2	2.35489576753001	0.129178952594838	0.614980141840384
GO:0140776	protein-containing complex destabilizing activity	3/1583	15/18639	0.2	2.35489576753001	0.129178952594838	0.614980141840384
GO:0001098	basal transcription machinery binding	8/1583	60/18639	0.133333333333333	1.56993051168667	0.133882267831507	0.631969687984318
GO:0001099	basal RNA polymerase II transcription machinery binding	8/1583	60/18639	0.133333333333333	1.56993051168667	0.133882267831507	0.631969687984318
GO:0060229	lipase activator activity	4/1583	24/18639	0.166666666666667	1.96241313960834	0.141584060238242	0.652969769619194
GO:0035198	miRNA binding	6/1583	42/18639	0.142857142857143	1.68206840537858	0.14226856076657	0.652969769619194
GO:0042056	chemoattractant activity	6/1583	42/18639	0.142857142857143	1.68206840537858	0.14226856076657	0.652969769619194
GO:0004540	RNA nuclease activity	14/1583	121/18639	0.115702479338843	1.36233639443885	0.14613126922568	0.652969769619194
GO:1902936	phosphatidylinositol bisphosphate binding	13/1583	111/18639	0.117117117117117	1.37899301702208	0.147222399121811	0.652969769619194
GO:0033192	calmodulin-dependent protein phosphatase activity	10/1583	81/18639	0.123456790123457	1.45363936267284	0.147628389908511	0.652969769619194
GO:0140791	histone H2AXS140 phosphatase activity	10/1583	81/18639	0.123456790123457	1.45363936267284	0.147628389908511	0.652969769619194
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	10/1583	81/18639	0.123456790123457	1.45363936267284	0.147628389908511	0.652969769619194
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	10/1583	81/18639	0.123456790123457	1.45363936267284	0.147628389908511	0.652969769619194
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	10/1583	81/18639	0.123456790123457	1.45363936267284	0.147628389908511	0.652969769619194
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	10/1583	81/18639	0.123456790123457	1.45363936267284	0.147628389908511	0.652969769619194
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	10/1583	81/18639	0.123456790123457	1.45363936267284	0.147628389908511	0.652969769619194
GO:1990439	MAP kinase serine/threonine phosphatase activity	10/1583	81/18639	0.123456790123457	1.45363936267284	0.147628389908511	0.652969769619194
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	7/1583	52/18639	0.134615384615385	1.58502599737597	0.149128418669103	0.652969769619194
GO:0005159	insulin-like growth factor receptor binding	3/1583	16/18639	0.1875	2.20771478205938	0.149467945469385	0.652969769619194
GO:0008391	arachidonate monooxygenase activity	3/1583	16/18639	0.1875	2.20771478205938	0.149467945469385	0.652969769619194
GO:0016675	oxidoreductase activity, acting on a heme group of donors	3/1583	16/18639	0.1875	2.20771478205938	0.149467945469385	0.652969769619194
GO:0017070	U6 snRNA binding	3/1583	16/18639	0.1875	2.20771478205938	0.149467945469385	0.652969769619194
GO:0097027	ubiquitin-protein transferase activator activity	3/1583	16/18639	0.1875	2.20771478205938	0.149467945469385	0.652969769619194
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6/1583	43/18639	0.13953488372093	1.64295053548605	0.154233077653877	0.6711548769782
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	10/1583	82/18639	0.121951219512195	1.43591205337195	0.156173452918546	0.671436153032578
GO:0033549	MAP kinase phosphatase activity	10/1583	82/18639	0.121951219512195	1.43591205337195	0.156173452918546	0.671436153032578
GO:1901981	phosphatidylinositol phosphate binding	20/1583	185/18639	0.108108108108108	1.2729166310973	0.157294206655667	0.671436153032578
GO:0030332	cyclin binding	5/1583	34/18639	0.147058823529412	1.73154100553677	0.157802509160313	0.671436153032578
GO:0000030	mannosyltransferase activity	4/1583	25/18639	0.16	1.88391661402401	0.157914068307482	0.671436153032578
GO:0017025	TBP-class protein binding	4/1583	25/18639	0.16	1.88391661402401	0.157914068307482	0.671436153032578
GO:0005246	calcium channel regulator activity	7/1583	53/18639	0.132075471698113	1.55511984648208	0.160069399207719	0.672895512141128
GO:0034212	protein N-acetyltransferase activity	7/1583	53/18639	0.132075471698113	1.55511984648208	0.160069399207719	0.672895512141128
GO:0140296	general transcription initiation factor binding	7/1583	53/18639	0.132075471698113	1.55511984648208	0.160069399207719	0.672895512141128
GO:0005507	copper ion binding	8/1583	63/18639	0.126984126984127	1.49517191589207	0.163237032580819	0.683631783064032
GO:0043539	protein serine/threonine kinase activator activity	9/1583	73/18639	0.123287671232877	1.45164807587466	0.164679303133932	0.685685232831874
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	10/1583	83/18639	0.120481927710843	1.41861190815061	0.164958386354526	0.685685232831874
GO:0001046	core promoter sequence-specific DNA binding	6/1583	44/18639	0.136363636363636	1.60561075058864	0.16662374012645	0.687477209262463
GO:0030547	signaling receptor inhibitor activity	6/1583	44/18639	0.136363636363636	1.60561075058864	0.16662374012645	0.687477209262463
GO:0004550	nucleoside diphosphate kinase activity	3/1583	17/18639	0.176470588235294	2.07784920664412	0.170688114419355	0.688936809649137
GO:0004659	prenyltransferase activity	3/1583	17/18639	0.176470588235294	2.07784920664412	0.170688114419355	0.688936809649137
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/1583	17/18639	0.176470588235294	2.07784920664412	0.170688114419355	0.688936809649137
GO:0017110	nucleoside diphosphate phosphatase activity	3/1583	17/18639	0.176470588235294	2.07784920664412	0.170688114419355	0.688936809649137
GO:0032977	membrane insertase activity	3/1583	17/18639	0.176470588235294	2.07784920664412	0.170688114419355	0.688936809649137
GO:0048038	quinone binding	3/1583	17/18639	0.176470588235294	2.07784920664412	0.170688114419355	0.688936809649137
GO:0015485	cholesterol binding	7/1583	54/18639	0.12962962962963	1.52632133080649	0.171360925184694	0.689155489731947
GO:0140566	histone reader activity	5/1583	35/18639	0.142857142857143	1.68206840537858	0.172100190359601	0.689638892304301
GO:0017018	myosin phosphatase activity	10/1583	84/18639	0.119047619047619	1.40172367114881	0.173976483172552	0.693362898672889
GO:0015216	purine nucleotide transmembrane transporter activity	4/1583	26/18639	0.153846153846154	1.81145828271539	0.17489674553598	0.693362898672889
GO:0070006	metalloaminopeptidase activity	4/1583	26/18639	0.153846153846154	1.81145828271539	0.17489674553598	0.693362898672889
GO:0046915	transition metal ion transmembrane transporter activity	6/1583	45/18639	0.133333333333333	1.56993051168667	0.179417403896229	0.706257907916605
GO:0051539	4 iron, 4 sulfur cluster binding	6/1583	45/18639	0.133333333333333	1.56993051168667	0.179417403896229	0.706257907916605
GO:0016922	nuclear receptor binding	15/1583	137/18639	0.109489051094891	1.28917651507117	0.186196809765201	0.727891945227221
GO:0000993	RNA polymerase II complex binding	5/1583	36/18639	0.138888888888889	1.63534428300695	0.186873515561028	0.727891945227221
GO:0044390	ubiquitin-like protein conjugating enzyme binding	5/1583	36/18639	0.138888888888889	1.63534428300695	0.186873515561028	0.727891945227221
GO:0019209	kinase activator activity	16/1583	148/18639	0.108108108108108	1.2729166310973	0.189773005203889	0.730151733400872
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	4/1583	27/18639	0.148148148148148	1.74436723520741	0.192465943365608	0.730151733400872
GO:0030291	protein serine/threonine kinase inhibitor activity	6/1583	46/18639	0.130434782608696	1.53580158751957	0.192589583008664	0.730151733400872
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	10/1583	86/18639	0.116279069767442	1.36912544623838	0.192682695186129	0.730151733400872
GO:0008308	voltage-gated monoatomic anion channel activity	3/1583	18/18639	0.166666666666667	1.96241313960834	0.192697136104	0.730151733400872
GO:0016854	racemase and epimerase activity	3/1583	18/18639	0.166666666666667	1.96241313960834	0.192697136104	0.730151733400872
GO:0017128	phospholipid scramblase activity	3/1583	18/18639	0.166666666666667	1.96241313960834	0.192697136104	0.730151733400872
GO:0070628	proteasome binding	3/1583	18/18639	0.166666666666667	1.96241313960834	0.192697136104	0.730151733400872
GO:0070851	growth factor receptor binding	15/1583	139/18639	0.107913669064748	1.27062721269605	0.201175347768749	0.731669847225251
GO:0022829	wide pore channel activity	5/1583	37/18639	0.135135135135135	1.59114578887163	0.202083715219609	0.731669847225251
GO:0043495	protein-membrane adaptor activity	6/1583	47/18639	0.127659574468085	1.50312495799788	0.206114655767166	0.731669847225251
GO:0061733	protein-lysine-acetyltransferase activity	6/1583	47/18639	0.127659574468085	1.50312495799788	0.206114655767166	0.731669847225251
GO:0140359	ABC-type transporter activity	6/1583	47/18639	0.127659574468085	1.50312495799788	0.206114655767166	0.731669847225251
GO:0004382	GDP phosphatase activity	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:0005031	tumor necrosis factor receptor activity	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:0005381	iron ion transmembrane transporter activity	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:0016783	sulfurtransferase activity	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:0016868	intramolecular phosphotransferase activity	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:0035256	G protein-coupled glutamate receptor binding	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:0043295	glutathione binding	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:0043422	protein kinase B binding	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:0099122	RNA polymerase II C-terminal domain binding	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:1905394	retromer complex binding	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:1990757	ubiquitin ligase activator activity	2/1583	10/18639	0.2	2.35489576753001	0.206233691228661	0.731669847225251
GO:0015932	nucleobase-containing compound transmembrane transporter activity	7/1583	57/18639	0.12280701754386	1.44598862918509	0.207170796487739	0.732661165991558
GO:0016741	transferase activity, transferring one-carbon groups	22/1583	215/18639	0.102325581395349	1.20483039268977	0.208992361629276	0.736764211566499
GO:0004197	cysteine-type endopeptidase activity	10/1583	88/18639	0.113636363636364	1.33800895882387	0.212228301459213	0.745811759702091
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/1583	19/18639	0.157894736842105	1.85912823752369	0.215356375986071	0.747373840649479
GO:0005520	insulin-like growth factor binding	3/1583	19/18639	0.157894736842105	1.85912823752369	0.215356375986071	0.747373840649479
GO:0046527	glucosyltransferase activity	3/1583	19/18639	0.157894736842105	1.85912823752369	0.215356375986071	0.747373840649479
GO:0097001	ceramide binding	3/1583	19/18639	0.157894736842105	1.85912823752369	0.215356375986071	0.747373840649479
GO:0001786	phosphatidylserine binding	7/1583	59/18639	0.11864406779661	1.3969720654839	0.232473411203245	0.783422903473268
GO:0004879	nuclear receptor activity	7/1583	59/18639	0.11864406779661	1.3969720654839	0.232473411203245	0.783422903473268
GO:0016758	hexosyltransferase activity	20/1583	197/18639	0.101522842639594	1.19537856219797	0.233043863381568	0.783422903473268
GO:0001222	transcription corepressor binding	6/1583	49/18639	0.122448979591837	1.44177291889592	0.234116524358425	0.783422903473268
GO:0000339	RNA cap binding	3/1583	20/18639	0.15	1.7661718256475	0.238532453272414	0.783422903473268
GO:0015095	magnesium ion transmembrane transporter activity	3/1583	20/18639	0.15	1.7661718256475	0.238532453272414	0.783422903473268
GO:0016505	peptidase activator activity involved in apoptotic process	3/1583	20/18639	0.15	1.7661718256475	0.238532453272414	0.783422903473268
GO:0031418	L-ascorbic acid binding	3/1583	20/18639	0.15	1.7661718256475	0.238532453272414	0.783422903473268
GO:0042288	MHC class I protein binding	3/1583	20/18639	0.15	1.7661718256475	0.238532453272414	0.783422903473268
GO:0052745	inositol phosphate phosphatase activity	3/1583	20/18639	0.15	1.7661718256475	0.238532453272414	0.783422903473268
GO:0003953	NAD+ nucleosidase activity	2/1583	11/18639	0.181818181818182	2.14081433411819	0.238689940568188	0.783422903473268
GO:0015173	aromatic amino acid transmembrane transporter activity	2/1583	11/18639	0.181818181818182	2.14081433411819	0.238689940568188	0.783422903473268
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/1583	11/18639	0.181818181818182	2.14081433411819	0.238689940568188	0.783422903473268
GO:0019107	myristoyltransferase activity	2/1583	11/18639	0.181818181818182	2.14081433411819	0.238689940568188	0.783422903473268
GO:0032050	clathrin heavy chain binding	2/1583	11/18639	0.181818181818182	2.14081433411819	0.238689940568188	0.783422903473268
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/1583	11/18639	0.181818181818182	2.14081433411819	0.238689940568188	0.783422903473268
GO:0097493	structural molecule activity conferring elasticity	2/1583	11/18639	0.181818181818182	2.14081433411819	0.238689940568188	0.783422903473268
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/1583	11/18639	0.181818181818182	2.14081433411819	0.238689940568188	0.783422903473268
GO:0008234	cysteine-type peptidase activity	19/1583	187/18639	0.101604278074866	1.19633742200722	0.239105733555576	0.783422903473268
GO:0004518	nuclease activity	21/1583	209/18639	0.100478468899522	1.18308160569689	0.240665797257282	0.784593478829682
GO:0001664	G protein-coupled receptor binding	29/1583	297/18639	0.0976430976430976	1.14969658684125	0.241248323165838	0.784593478829682
GO:0016782	transferase activity, transferring sulphur-containing groups	8/1583	70/18639	0.114285714285714	1.34565472430286	0.241575909549893	0.784593478829682
GO:0072341	modified amino acid binding	10/1583	91/18639	0.10989010989011	1.29389877336814	0.242964089554319	0.786513197369149
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	7/1583	60/18639	0.116666666666667	1.37368919772584	0.245494882969324	0.786513197369149
GO:0098531	ligand-modulated transcription factor activity	7/1583	60/18639	0.116666666666667	1.37368919772584	0.245494882969324	0.786513197369149
GO:0140597	protein carrier chaperone	19/1583	188/18639	0.101063829787234	1.18997392508165	0.246332813386713	0.786513197369149
GO:0015215	nucleotide transmembrane transporter activity	4/1583	30/18639	0.133333333333333	1.56993051168667	0.248019692333201	0.786513197369149
GO:0031624	ubiquitin conjugating enzyme binding	4/1583	30/18639	0.133333333333333	1.56993051168667	0.248019692333201	0.786513197369149
GO:0048019	receptor antagonist activity	4/1583	30/18639	0.133333333333333	1.56993051168667	0.248019692333201	0.786513197369149
GO:0032813	tumor necrosis factor receptor superfamily binding	6/1583	50/18639	0.12	1.412937460518	0.248538189105178	0.786513197369149
GO:0004177	aminopeptidase activity	5/1583	40/18639	0.125	1.47180985470625	0.249933278158599	0.786513197369149
GO:0030331	nuclear estrogen receptor binding	5/1583	40/18639	0.125	1.47180985470625	0.249933278158599	0.786513197369149
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	5/1583	40/18639	0.125	1.47180985470625	0.249933278158599	0.786513197369149
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	17/1583	167/18639	0.101796407185629	1.19859964215599	0.25201216425856	0.788599862314709
GO:0016874	ligase activity	17/1583	167/18639	0.101796407185629	1.19859964215599	0.25201216425856	0.788599862314709
GO:0043178	alcohol binding	10/1583	92/18639	0.108695652173913	1.27983465626631	0.253548667803293	0.791185478803554
GO:0004722	protein serine/threonine phosphatase activity	11/1583	103/18639	0.106796116504854	1.25746861372961	0.25752099183685	0.799727388095811
GO:0005201	extracellular matrix structural constituent	17/1583	168/18639	0.101190476190476	1.19146512047649	0.259872832932368	0.799727388095811
GO:0003713	transcription coactivator activity	25/1583	256/18639	0.09765625	1.14985144898926	0.26068750254444	0.799727388095811
GO:0001846	opsonin binding	3/1583	21/18639	0.142857142857143	1.68206840537858	0.26209841521583	0.799727388095811
GO:0035613	RNA stem-loop binding	3/1583	21/18639	0.142857142857143	1.68206840537858	0.26209841521583	0.799727388095811
GO:1904047	S-adenosyl-L-methionine binding	3/1583	21/18639	0.142857142857143	1.68206840537858	0.26209841521583	0.799727388095811
GO:0005048	signal sequence binding	6/1583	51/18639	0.117647058823529	1.38523280442942	0.263202857019402	0.799727388095811
GO:0019838	growth factor binding	14/1583	136/18639	0.102941176470588	1.21207870387574	0.264757131171669	0.799727388095811
GO:0001530	lipopolysaccharide binding	5/1583	41/18639	0.121951219512195	1.43591205337195	0.266486263411123	0.799727388095811
GO:0016878	acid-thiol ligase activity	4/1583	31/18639	0.129032258064516	1.51928759195484	0.267263191633253	0.799727388095811
GO:0017147	Wnt-protein binding	4/1583	31/18639	0.129032258064516	1.51928759195484	0.267263191633253	0.799727388095811
GO:0047499	calcium-independent phospholipase A2 activity	4/1583	31/18639	0.129032258064516	1.51928759195484	0.267263191633253	0.799727388095811
GO:0070273	phosphatidylinositol-4-phosphate binding	4/1583	31/18639	0.129032258064516	1.51928759195484	0.267263191633253	0.799727388095811
GO:0001221	transcription coregulator binding	12/1583	115/18639	0.104347826086957	1.22864127001566	0.270311879987439	0.799727388095811
GO:0005049	nuclear export signal receptor activity	2/1583	12/18639	0.166666666666667	1.96241313960834	0.271361716966083	0.799727388095811
GO:0005165	neurotrophin receptor binding	2/1583	12/18639	0.166666666666667	1.96241313960834	0.271361716966083	0.799727388095811
GO:0010853	cyclase activator activity	2/1583	12/18639	0.166666666666667	1.96241313960834	0.271361716966083	0.799727388095811
GO:0016423	tRNA (guanine) methyltransferase activity	2/1583	12/18639	0.166666666666667	1.96241313960834	0.271361716966083	0.799727388095811
GO:0035251	UDP-glucosyltransferase activity	2/1583	12/18639	0.166666666666667	1.96241313960834	0.271361716966083	0.799727388095811
GO:0070008	serine-type exopeptidase activity	2/1583	12/18639	0.166666666666667	1.96241313960834	0.271361716966083	0.799727388095811
GO:0070679	inositol 1,4,5 trisphosphate binding	2/1583	12/18639	0.166666666666667	1.96241313960834	0.271361716966083	0.799727388095811
GO:0042562	hormone binding	10/1583	94/18639	0.106382978723404	1.2526041316649	0.275165358790134	0.808797387050683
GO:0019783	ubiquitin-like protein peptidase activity	13/1583	127/18639	0.102362204724409	1.20526161330276	0.28167815470933	0.824201912707811
GO:0004402	histone acetyltransferase activity	5/1583	42/18639	0.119047619047619	1.40172367114881	0.283272439444171	0.824201912707811
GO:0043175	RNA polymerase core enzyme binding	5/1583	42/18639	0.119047619047619	1.40172367114881	0.283272439444171	0.824201912707811
GO:0008168	methyltransferase activity	20/1583	204/18639	0.0980392156862745	1.15436067035785	0.28336564862396	0.824201912707811
GO:0008649	rRNA methyltransferase activity	3/1583	22/18639	0.136363636363636	1.60561075058864	0.285934584094363	0.825455612288883
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/1583	22/18639	0.136363636363636	1.60561075058864	0.285934584094363	0.825455612288883
GO:0047498	calcium-dependent phospholipase A2 activity	4/1583	32/18639	0.125	1.47180985470625	0.28676061216858	0.825455612288883
GO:0140142	nucleocytoplasmic carrier activity	4/1583	32/18639	0.125	1.47180985470625	0.28676061216858	0.825455612288883
GO:0048029	monosaccharide binding	8/1583	74/18639	0.108108108108108	1.2729166310973	0.291082398648253	0.833077580810102
GO:0005178	integrin binding	16/1583	161/18639	0.0993788819875776	1.17013454287205	0.292312411791561	0.833077580810102
GO:0005544	calcium-dependent phospholipid binding	6/1583	53/18639	0.113207547169811	1.33295986841321	0.293147586784165	0.833077580810102
GO:0008146	sulfotransferase activity	6/1583	53/18639	0.113207547169811	1.33295986841321	0.293147586784165	0.833077580810102
GO:1901505	carbohydrate derivative transmembrane transporter activity	6/1583	53/18639	0.113207547169811	1.33295986841321	0.293147586784165	0.833077580810102
GO:0008237	metallopeptidase activity	18/1583	184/18639	0.0978260869565217	1.15185119063968	0.29989096484599	0.840277986122851
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	22/1583	229/18639	0.0960698689956332	1.13117263942489	0.303781776576526	0.840277986122851
GO:0004535	poly(A)-specific ribonuclease activity	2/1583	13/18639	0.153846153846154	1.81145828271539	0.30397848151482	0.840277986122851
GO:0005035	death receptor activity	2/1583	13/18639	0.153846153846154	1.81145828271539	0.30397848151482	0.840277986122851
GO:0005172	vascular endothelial growth factor receptor binding	2/1583	13/18639	0.153846153846154	1.81145828271539	0.30397848151482	0.840277986122851
GO:0019855	calcium channel inhibitor activity	2/1583	13/18639	0.153846153846154	1.81145828271539	0.30397848151482	0.840277986122851
GO:0031994	insulin-like growth factor I binding	2/1583	13/18639	0.153846153846154	1.81145828271539	0.30397848151482	0.840277986122851
GO:0039706	co-receptor binding	2/1583	13/18639	0.153846153846154	1.81145828271539	0.30397848151482	0.840277986122851
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/1583	13/18639	0.153846153846154	1.81145828271539	0.30397848151482	0.840277986122851
GO:0089720	caspase binding	2/1583	13/18639	0.153846153846154	1.81145828271539	0.30397848151482	0.840277986122851
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/1583	13/18639	0.153846153846154	1.81145828271539	0.30397848151482	0.840277986122851
GO:0005516	calmodulin binding	20/1583	207/18639	0.0966183574879227	1.13763080557005	0.306017334176527	0.840848528394808
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	4/1583	33/18639	0.121212121212121	1.42720955607879	0.306449284136708	0.840848528394808
GO:0140311	protein sequestering activity	4/1583	33/18639	0.121212121212121	1.42720955607879	0.306449284136708	0.840848528394808
GO:0000295	adenine nucleotide transmembrane transporter activity	3/1583	23/18639	0.130434782608696	1.53580158751957	0.309929131556464	0.843677062742376
GO:0005158	insulin receptor binding	3/1583	23/18639	0.130434782608696	1.53580158751957	0.309929131556464	0.843677062742376
GO:0140102	catalytic activity, acting on a rRNA	3/1583	23/18639	0.130434782608696	1.53580158751957	0.309929131556464	0.843677062742376
GO:0016798	hydrolase activity, acting on glycosyl bonds	13/1583	130/18639	0.1	1.177447883765	0.310509511422239	0.843677062742376
GO:0005126	cytokine receptor binding	26/1583	275/18639	0.0945454545454545	1.11322345374146	0.312054608178013	0.845812246983714
GO:0030020	extracellular matrix structural constituent conferring tensile strength	5/1583	44/18639	0.113636363636364	1.33800895882387	0.317383041646756	0.856088882311106
GO:0043014	alpha-tubulin binding	5/1583	44/18639	0.113636363636364	1.33800895882387	0.317383041646756	0.856088882311106
GO:0140313	molecular sequestering activity	6/1583	55/18639	0.109090909090909	1.28448860047091	0.323724090955789	0.867254265451853
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	4/1583	34/18639	0.117647058823529	1.38523280442942	0.32626885413356	0.867254265451853
GO:0052866	phosphatidylinositol phosphate phosphatase activity	4/1583	34/18639	0.117647058823529	1.38523280442942	0.32626885413356	0.867254265451853
GO:0008235	metalloexopeptidase activity	7/1583	66/18639	0.106060606060606	1.24880836156894	0.327499261449812	0.867254265451853
GO:0003724	RNA helicase activity	8/1583	77/18639	0.103896103896104	1.22332247663896	0.329697507371387	0.867254265451853
GO:0001091	RNA polymerase II general transcription initiation factor binding	3/1583	24/18639	0.125	1.47180985470625	0.333978427459066	0.867254265451853
GO:0035035	histone acetyltransferase binding	3/1583	24/18639	0.125	1.47180985470625	0.333978427459066	0.867254265451853
GO:0042605	peptide antigen binding	5/1583	45/18639	0.111111111111111	1.30827542640556	0.334628746365573	0.867254265451853
GO:0008195	phosphatidate phosphatase activity	2/1583	14/18639	0.142857142857143	1.68206840537858	0.336314041898744	0.867254265451853
GO:0008559	ABC-type xenobiotic transporter activity	2/1583	14/18639	0.142857142857143	1.68206840537858	0.336314041898744	0.867254265451853
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/1583	14/18639	0.142857142857143	1.68206840537858	0.336314041898744	0.867254265451853
GO:0032036	myosin heavy chain binding	2/1583	14/18639	0.142857142857143	1.68206840537858	0.336314041898744	0.867254265451853
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/1583	14/18639	0.142857142857143	1.68206840537858	0.336314041898744	0.867254265451853
GO:0042043	neurexin family protein binding	2/1583	14/18639	0.142857142857143	1.68206840537858	0.336314041898744	0.867254265451853
GO:0042813	Wnt receptor activity	2/1583	14/18639	0.142857142857143	1.68206840537858	0.336314041898744	0.867254265451853
GO:0044548	S100 protein binding	2/1583	14/18639	0.142857142857143	1.68206840537858	0.336314041898744	0.867254265451853
GO:0046030	inositol trisphosphate phosphatase activity	2/1583	14/18639	0.142857142857143	1.68206840537858	0.336314041898744	0.867254265451853
GO:1901612	cardiolipin binding	2/1583	14/18639	0.142857142857143	1.68206840537858	0.336314041898744	0.867254265451853
GO:1990825	sequence-specific mRNA binding	2/1583	14/18639	0.142857142857143	1.68206840537858	0.336314041898744	0.867254265451853
GO:0019955	cytokine binding	14/1583	144/18639	0.0972222222222222	1.14474099810486	0.33874732758891	0.871511600309574
GO:0008173	RNA methyltransferase activity	7/1583	67/18639	0.104477611940299	1.23016943079926	0.341616088888413	0.874567561111019
GO:0003727	single-stranded RNA binding	9/1583	89/18639	0.101123595505618	1.19067763526798	0.3430754256782	0.874567561111019
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	9/1583	89/18639	0.101123595505618	1.19067763526798	0.3430754256782	0.874567561111019
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	9/1583	89/18639	0.101123595505618	1.19067763526798	0.3430754256782	0.874567561111019
GO:0000175	3'-5'-RNA exonuclease activity	4/1583	35/18639	0.114285714285714	1.34565472430286	0.346161584943103	0.876418194605948
GO:0004623	phospholipase A2 activity	4/1583	35/18639	0.114285714285714	1.34565472430286	0.346161584943103	0.876418194605948
GO:0005154	epidermal growth factor receptor binding	4/1583	35/18639	0.114285714285714	1.34565472430286	0.346161584943103	0.876418194605948
GO:0004180	carboxypeptidase activity	5/1583	46/18639	0.108695652173913	1.27983465626631	0.351950595555439	0.882295895861966
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	5/1583	46/18639	0.108695652173913	1.27983465626631	0.351950595555439	0.882295895861966
GO:0016247	channel regulator activity	16/1583	168/18639	0.0952380952380952	1.12137893691905	0.35360126750548	0.882295895861966
GO:0016504	peptidase activator activity	6/1583	57/18639	0.105263157894737	1.23941882501579	0.354709887851492	0.882295895861966
GO:0140793	histone H2AXY142 phosphatase activity	9/1583	90/18639	0.1	1.177447883765	0.355356860151266	0.882295895861966
GO:0008186	ATP-dependent activity, acting on RNA	8/1583	79/18639	0.10126582278481	1.19235228735697	0.355901024830692	0.882295895861966
GO:0046332	SMAD binding	8/1583	79/18639	0.10126582278481	1.19235228735697	0.355901024830692	0.882295895861966
GO:0001848	complement binding	3/1583	25/18639	0.12	1.412937460518	0.35798720370701	0.882295895861966
GO:0003707	nuclear steroid receptor activity	3/1583	25/18639	0.12	1.412937460518	0.35798720370701	0.882295895861966
GO:0005537	D-mannose binding	3/1583	25/18639	0.12	1.412937460518	0.35798720370701	0.882295895861966
GO:0017056	structural constituent of nuclear pore	3/1583	25/18639	0.12	1.412937460518	0.35798720370701	0.882295895861966
GO:0019211	phosphatase activator activity	3/1583	25/18639	0.12	1.412937460518	0.35798720370701	0.882295895861966
GO:0005484	SNAP receptor activity	4/1583	36/18639	0.111111111111111	1.30827542640556	0.366072593615863	0.89358085030111
GO:0055106	ubiquitin-protein transferase regulator activity	4/1583	36/18639	0.111111111111111	1.30827542640556	0.366072593615863	0.89358085030111
GO:0016846	carbon-sulfur lyase activity	2/1583	15/18639	0.133333333333333	1.56993051168667	0.36818097871473	0.89358085030111
GO:0031005	filamin binding	2/1583	15/18639	0.133333333333333	1.56993051168667	0.36818097871473	0.89358085030111
GO:0042809	nuclear vitamin D receptor binding	2/1583	15/18639	0.133333333333333	1.56993051168667	0.36818097871473	0.89358085030111
GO:0051371	muscle alpha-actinin binding	2/1583	15/18639	0.133333333333333	1.56993051168667	0.36818097871473	0.89358085030111
GO:0061578	K63-linked deubiquitinase activity	2/1583	15/18639	0.133333333333333	1.56993051168667	0.36818097871473	0.89358085030111
GO:0140789	histone phosphatase activity	13/1583	136/18639	0.0955882352941176	1.1255016535989	0.370139673648881	0.894797843078322
GO:0008408	3'-5' exonuclease activity	6/1583	58/18639	0.103448275862069	1.21804953492931	0.370288874020742	0.894797843078322
GO:0141108	transporter regulator activity	16/1583	170/18639	0.0941176470588235	1.10818624354353	0.371580097491311	0.895974520790738
GO:0035091	phosphatidylinositol binding	26/1583	284/18639	0.0915492957746479	1.07794524570036	0.373676266085905	0.899082851878398
GO:0022804	active transmembrane transporter activity	41/1583	457/18639	0.0897155361050328	1.05635368127714	0.379394790182017	0.910532596955564
GO:0052689	carboxylic ester hydrolase activity	9/1583	92/18639	0.0978260869565217	1.15185119063968	0.3800697105784	0.910532596955564
GO:0005160	transforming growth factor beta receptor binding	3/1583	26/18639	0.115384615384615	1.35859371203654	0.381868567816274	0.910924163912912
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/1583	26/18639	0.115384615384615	1.35859371203654	0.381868567816274	0.910924163912912
GO:0019213	deacetylase activity	4/1583	37/18639	0.108108108108108	1.2729166310973	0.385950033421469	0.914562838993465
GO:0043394	proteoglycan binding	4/1583	37/18639	0.108108108108108	1.2729166310973	0.385950033421469	0.914562838993465
GO:0032266	phosphatidylinositol-3-phosphate binding	5/1583	48/18639	0.104166666666667	1.22650821225521	0.386677825104059	0.914562838993465
GO:0043138	3'-5' DNA helicase activity	5/1583	48/18639	0.104166666666667	1.22650821225521	0.386677825104059	0.914562838993465
GO:0003688	DNA replication origin binding	2/1583	16/18639	0.125	1.47180985470625	0.399425697749779	0.933884671170996
GO:0005521	lamin binding	2/1583	16/18639	0.125	1.47180985470625	0.399425697749779	0.933884671170996
GO:0022858	alanine transmembrane transporter activity	2/1583	16/18639	0.125	1.47180985470625	0.399425697749779	0.933884671170996
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/1583	16/18639	0.125	1.47180985470625	0.399425697749779	0.933884671170996
GO:0070411	I-SMAD binding	2/1583	16/18639	0.125	1.47180985470625	0.399425697749779	0.933884671170996
GO:0030295	protein kinase activator activity	13/1583	139/18639	0.0935251798561151	1.10121025100324	0.400555744550037	0.933884671170996
GO:0035254	glutamate receptor binding	5/1583	49/18639	0.102040816326531	1.20147743241327	0.404014336552426	0.933884671170996
GO:0001671	ATPase activator activity	3/1583	27/18639	0.111111111111111	1.30827542640556	0.405543895872607	0.933884671170996
GO:0005385	zinc ion transmembrane transporter activity	3/1583	27/18639	0.111111111111111	1.30827542640556	0.405543895872607	0.933884671170996
GO:0008266	poly(U) RNA binding	3/1583	27/18639	0.111111111111111	1.30827542640556	0.405543895872607	0.933884671170996
GO:0008395	steroid hydroxylase activity	3/1583	27/18639	0.111111111111111	1.30827542640556	0.405543895872607	0.933884671170996
GO:0023026	MHC class II protein complex binding	3/1583	27/18639	0.111111111111111	1.30827542640556	0.405543895872607	0.933884671170996
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	4/1583	38/18639	0.105263157894737	1.23941882501579	0.405745225176626	0.933884671170996
GO:0000149	SNARE binding	10/1583	106/18639	0.0943396226415094	1.11079989034434	0.412819866707293	0.948208930952422
GO:0140713	histone chaperone activity	15/1583	164/18639	0.0914634146341463	1.07693404002897	0.421486607980054	0.957870766007867
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/1583	39/18639	0.102564102564103	1.20763885514359	0.425412743288769	0.957870766007867
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	12/1583	130/18639	0.0923076923076923	1.08687496962923	0.425730484075135	0.957870766007867
GO:0019789	SUMO transferase activity	3/1583	28/18639	0.107142857142857	1.26155130403393	0.428942630154356	0.957870766007867
GO:0036408	histone H3K14 acetyltransferase activity	3/1583	28/18639	0.107142857142857	1.26155130403393	0.428942630154356	0.957870766007867
GO:0046625	sphingolipid binding	3/1583	28/18639	0.107142857142857	1.26155130403393	0.428942630154356	0.957870766007867
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/1583	28/18639	0.107142857142857	1.26155130403393	0.428942630154356	0.957870766007867
GO:0097718	disordered domain specific binding	3/1583	28/18639	0.107142857142857	1.26155130403393	0.428942630154356	0.957870766007867
GO:0005092	GDP-dissociation inhibitor activity	2/1583	17/18639	0.117647058823529	1.38523280442942	0.429924042193836	0.957870766007867
GO:0016805	dipeptidase activity	2/1583	17/18639	0.117647058823529	1.38523280442942	0.429924042193836	0.957870766007867
GO:0031489	myosin V binding	2/1583	17/18639	0.117647058823529	1.38523280442942	0.429924042193836	0.957870766007867
GO:0045236	CXCR chemokine receptor binding	2/1583	17/18639	0.117647058823529	1.38523280442942	0.429924042193836	0.957870766007867
GO:0070403	NAD+ binding	2/1583	17/18639	0.117647058823529	1.38523280442942	0.429924042193836	0.957870766007867
GO:0070492	oligosaccharide binding	2/1583	17/18639	0.117647058823529	1.38523280442942	0.429924042193836	0.957870766007867
GO:1990226	histone methyltransferase binding	2/1583	17/18639	0.117647058823529	1.38523280442942	0.429924042193836	0.957870766007867
GO:0004532	RNA exonuclease activity	4/1583	40/18639	0.1	1.177447883765	0.444910461636567	0.987311263472381
GO:0071949	FAD binding	4/1583	40/18639	0.1	1.177447883765	0.444910461636567	0.987311263472381
GO:0004181	metallocarboxypeptidase activity	3/1583	29/18639	0.103448275862069	1.21804953492931	0.452002002856747	0.997089566697853
GO:0010484	histone H3 acetyltransferase activity	3/1583	29/18639	0.103448275862069	1.21804953492931	0.452002002856747	0.997089566697853
GO:0035250	UDP-galactosyltransferase activity	3/1583	29/18639	0.103448275862069	1.21804953492931	0.452002002856747	0.997089566697853
GO:0004725	protein tyrosine phosphatase activity	9/1583	98/18639	0.0918367346938776	1.08132968917194	0.454491041953727	0.999999999999841
GO:0042277	peptide binding	22/1583	249/18639	0.0883534136546185	1.04031539931044	0.455656340966938	0.999999999999841
GO:0004706	JUN kinase kinase kinase activity	2/1583	18/18639	0.111111111111111	1.30827542640556	0.459577405455065	0.999999999999841
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/1583	18/18639	0.111111111111111	1.30827542640556	0.459577405455065	0.999999999999841
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/1583	18/18639	0.111111111111111	1.30827542640556	0.459577405455065	0.999999999999841
GO:1901611	phosphatidylglycerol binding	2/1583	18/18639	0.111111111111111	1.30827542640556	0.459577405455065	0.999999999999841
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	11/1583	122/18639	0.0901639344262295	1.0616333378209	0.464154367061101	0.999999999999841
GO:0042287	MHC protein binding	4/1583	41/18639	0.0975609756097561	1.14872964269756	0.464199564147425	0.999999999999841
GO:0001968	fibronectin binding	3/1583	30/18639	0.1	1.177447883765	0.47466670402603	0.999999999999841
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/1583	30/18639	0.1	1.177447883765	0.47466670402603	0.999999999999841
GO:0008187	poly-pyrimidine tract binding	3/1583	30/18639	0.1	1.177447883765	0.47466670402603	0.999999999999841
GO:0016769	transferase activity, transferring nitrogenous groups	3/1583	30/18639	0.1	1.177447883765	0.47466670402603	0.999999999999841
GO:0033612	receptor serine/threonine kinase binding	3/1583	30/18639	0.1	1.177447883765	0.47466670402603	0.999999999999841
GO:0043995	histone H4K5 acetyltransferase activity	3/1583	30/18639	0.1	1.177447883765	0.47466670402603	0.999999999999841
GO:0043996	histone H4K8 acetyltransferase activity	3/1583	30/18639	0.1	1.177447883765	0.47466670402603	0.999999999999841
GO:0043997	histone H4K12 acetyltransferase activity	3/1583	30/18639	0.1	1.177447883765	0.47466670402603	0.999999999999841
GO:0031492	nucleosomal DNA binding	4/1583	42/18639	0.0952380952380952	1.12137893691905	0.483244524642505	0.999999999999841
GO:0042577	lipid phosphatase activity	2/1583	19/18639	0.105263157894737	1.23941882501579	0.488309291274947	0.999999999999841
GO:0140463	chromatin-protein adaptor activity	5/1583	54/18639	0.0925925925925926	1.09022952200463	0.48919391809078	0.999999999999841
GO:0005164	tumor necrosis factor receptor binding	3/1583	31/18639	0.0967741935483871	1.13946569396613	0.496888508925256	0.999999999999841
GO:0008327	methyl-CpG binding	3/1583	31/18639	0.0967741935483871	1.13946569396613	0.496888508925256	0.999999999999841
GO:0004712	protein serine/threonine/tyrosine kinase activity	4/1583	43/18639	0.0930232558139535	1.0953003569907	0.502013060212236	0.999999999999841
GO:0098632	cell-cell adhesion mediator activity	5/1583	55/18639	0.0909090909090909	1.07040716705909	0.505740900804278	0.999999999999841
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	8/1583	91/18639	0.0879120879120879	1.03511901869451	0.513451180082864	0.999999999999841
GO:0061608	nuclear import signal receptor activity	2/1583	20/18639	0.1	1.177447883765	0.516062273275229	0.999999999999841
GO:0043425	bHLH transcription factor binding	3/1583	32/18639	0.09375	1.10385739102969	0.518625877555257	0.999999999999841
GO:0070717	poly-purine tract binding	3/1583	32/18639	0.09375	1.10385739102969	0.518625877555257	0.999999999999841
GO:0004519	endonuclease activity	11/1583	127/18639	0.0866141732283465	1.01983674971772	0.518891891905664	0.999999999999841
GO:0000510	H3-H4 histone complex chaperone activity	13/1583	151/18639	0.0860927152317881	1.01369685357252	0.521898900695659	0.999999999999841
GO:0140584	chromatin extrusion motor activity	13/1583	151/18639	0.0860927152317881	1.01369685357252	0.521898900695659	0.999999999999841
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	13/1583	151/18639	0.0860927152317881	1.01369685357252	0.521898900695659	0.999999999999841
GO:0140849	ATP-dependent H2AZ histone chaperone activity	13/1583	151/18639	0.0860927152317881	1.01369685357252	0.521898900695659	0.999999999999841
GO:0030145	manganese ion binding	6/1583	68/18639	0.0882352941176471	1.03892460332206	0.523522585302773	0.999999999999841
GO:1990841	promoter-specific chromatin binding	6/1583	68/18639	0.0882352941176471	1.03892460332206	0.523522585302773	0.999999999999841
GO:0015616	DNA translocase activity	13/1583	152/18639	0.0855263157894737	1.00702779532533	0.531768145934653	0.999999999999841
GO:0046906	tetrapyrrole binding	13/1583	152/18639	0.0855263157894737	1.00702779532533	0.531768145934653	0.999999999999841
GO:0140674	ATP-dependent histone chaperone activity	13/1583	152/18639	0.0855263157894737	1.00702779532533	0.531768145934653	0.999999999999841
GO:0008009	chemokine activity	4/1583	45/18639	0.0888888888888889	1.04662034112445	0.538607507503243	0.999999999999841
GO:0140303	intramembrane lipid transporter activity	4/1583	45/18639	0.0888888888888889	1.04662034112445	0.538607507503243	0.999999999999841
GO:0019956	chemokine binding	3/1583	33/18639	0.0909090909090909	1.07040716705909	0.539843536897112	0.999999999999841
GO:0061775	cohesin loader activity	13/1583	153/18639	0.0849673202614379	1.00044591431013	0.541573344684209	0.999999999999841
GO:0009975	cyclase activity	2/1583	21/18639	0.0952380952380952	1.12137893691905	0.542795310965692	0.999999999999841
GO:0010314	phosphatidylinositol-5-phosphate binding	2/1583	21/18639	0.0952380952380952	1.12137893691905	0.542795310965692	0.999999999999841
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/1583	21/18639	0.0952380952380952	1.12137893691905	0.542795310965692	0.999999999999841
GO:0061891	calcium ion sensor activity	2/1583	21/18639	0.0952380952380952	1.12137893691905	0.542795310965692	0.999999999999841
GO:0072542	protein phosphatase activator activity	2/1583	21/18639	0.0952380952380952	1.12137893691905	0.542795310965692	0.999999999999841
GO:0140312	cargo adaptor activity	2/1583	21/18639	0.0952380952380952	1.12137893691905	0.542795310965692	0.999999999999841
GO:0016791	phosphatase activity	23/1583	273/18639	0.0842490842490843	0.991989059582237	0.548123735951076	0.999999999999841
GO:0004497	monooxygenase activity	9/1583	106/18639	0.0849056603773585	0.999719901309908	0.550935369063574	0.999999999999841
GO:0020037	heme binding	12/1583	142/18639	0.0845070422535211	0.995026380646482	0.551078537655493	0.999999999999841
GO:0008175	tRNA methyltransferase activity	3/1583	34/18639	0.0882352941176471	1.03892460332206	0.560512054583907	0.999999999999841
GO:0008093	cytoskeletal anchor activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0008970	phospholipase A1 activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0031683	G-protein beta/gamma-subunit complex binding	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0032931	histone H3K56 acetyltransferase activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0043992	histone H3K9 acetyltransferase activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0043993	histone H3K18 acetyltransferase activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0043994	histone H3K23 acetyltransferase activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0043999	histone H2AK5 acetyltransferase activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0044012	histone H2AK9 acetyltransferase activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0044014	histone H2BK5 acetyltransferase activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0044015	histone H2BK12 acetyltransferase activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0044016	histone H3K4 acetyltransferase activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0044017	histone H3K27 acetyltransferase activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0044018	histone H3K36 acetyltransferase activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0046972	histone H4K16 acetyltransferase activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0070034	telomerase RNA binding	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0140784	metal ion sensor activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0140908	histone H3K122 acetyltransferase activity	2/1583	22/18639	0.0909090909090909	1.07040716705909	0.568481383652825	0.999999999999841
GO:0015459	potassium channel regulator activity	5/1583	59/18639	0.0847457627118644	0.997837189631359	0.569565661718026	0.999999999999841
GO:0070888	E-box binding	5/1583	59/18639	0.0847457627118644	0.997837189631359	0.569565661718026	0.999999999999841
GO:0061659	ubiquitin-like protein ligase activity	31/1583	372/18639	0.0833333333333333	0.981206569804169	0.571935972058316	0.999999999999841
GO:0005504	fatty acid binding	4/1583	47/18639	0.0851063829787234	1.00208330533192	0.573786434334723	0.999999999999841
GO:1990518	single-stranded 3'-5' DNA helicase activity	4/1583	47/18639	0.0851063829787234	1.00208330533192	0.573786434334723	0.999999999999841
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	15/1583	181/18639	0.0828729281767956	0.975785539031771	0.578721808189939	0.999999999999841
GO:0010485	histone H4 acetyltransferase activity	3/1583	35/18639	0.0857142857142857	1.00924104322715	0.580607411112733	0.999999999999841
GO:0043015	gamma-tubulin binding	3/1583	35/18639	0.0857142857142857	1.00924104322715	0.580607411112733	0.999999999999841
GO:0003697	single-stranded DNA binding	10/1583	121/18639	0.0826446280991736	0.973097424599176	0.583562071895041	0.999999999999841
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	5/1583	60/18639	0.0833333333333333	0.981206569804169	0.584845253568003	0.999999999999841
GO:0000182	rDNA binding	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0004090	carbonyl reductase (NADPH) activity	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0004935	adrenergic receptor activity	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0005131	growth hormone receptor binding	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0005345	purine nucleobase transmembrane transporter activity	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0008140	cAMP response element binding protein binding	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0008239	dipeptidyl-peptidase activity	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0015203	polyamine transmembrane transporter activity	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0015643	toxic substance binding	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0031419	cobalamin binding	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0031996	thioesterase binding	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0032395	MHC class II receptor activity	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0050308	sugar-phosphatase activity	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0050815	phosphoserine residue binding	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0051378	serotonin binding	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0071723	lipopeptide binding	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0098505	G-rich strand telomeric DNA binding	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/1583	10/18639	0.1	1.177447883765	0.588425517363962	0.999999999999841
GO:0140658	ATP-dependent chromatin remodeler activity	13/1583	158/18639	0.0822784810126582	0.968786233477534	0.589467190296049	0.999999999999841
GO:0009378	four-way junction helicase activity	4/1583	48/18639	0.0833333333333333	0.981206569804169	0.590796307901147	0.999999999999841
GO:0016849	phosphorus-oxygen lyase activity	2/1583	23/18639	0.0869565217391304	1.02386772501305	0.593105407662003	0.999999999999841
GO:0044013	histone H2B acetyltransferase activity	2/1583	23/18639	0.0869565217391304	1.02386772501305	0.593105407662003	0.999999999999841
GO:0099186	structural constituent of postsynapse	2/1583	23/18639	0.0869565217391304	1.02386772501305	0.593105407662003	0.999999999999841
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	2/1583	23/18639	0.0869565217391304	1.02386772501305	0.593105407662003	0.999999999999841
GO:0004222	metalloendopeptidase activity	9/1583	110/18639	0.0818181818181818	0.963366450353184	0.596569218243022	0.999999999999841
GO:0008170	N-methyltransferase activity	8/1583	98/18639	0.0816326530612245	0.961181945930615	0.599494772947083	0.999999999999841
GO:0042626	ATPase-coupled transmembrane transporter activity	8/1583	98/18639	0.0816326530612245	0.961181945930615	0.599494772947083	0.999999999999841
GO:0015026	coreceptor activity	5/1583	61/18639	0.0819672131147541	0.965121216200822	0.599825781182214	0.999999999999841
GO:0004033	aldo-keto reductase (NADPH) activity	3/1583	36/18639	0.0833333333333333	0.981206569804169	0.600110576339721	0.999999999999841
GO:0045505	dynein intermediate chain binding	3/1583	36/18639	0.0833333333333333	0.981206569804169	0.600110576339721	0.999999999999841
GO:0061630	ubiquitin protein ligase activity	29/1583	353/18639	0.0821529745042493	0.967308459750286	0.603102332549634	0.999999999999841
GO:0050660	flavin adenine dinucleotide binding	7/1583	86/18639	0.0813953488372093	0.958387812366863	0.603206929984213	0.999999999999841
GO:0003689	DNA clamp loader activity	13/1583	160/18639	0.08125	0.956676405559065	0.608013046204521	0.999999999999841
GO:0099106	ion channel regulator activity	13/1583	160/18639	0.08125	0.956676405559065	0.608013046204521	0.999999999999841
GO:0031491	nucleosome binding	6/1583	74/18639	0.0810810810810811	0.954687473322976	0.608028379097282	0.999999999999841
GO:0035064	methylated histone binding	6/1583	74/18639	0.0810810810810811	0.954687473322976	0.608028379097282	0.999999999999841
GO:0004622	lysophospholipase activity	2/1583	24/18639	0.0833333333333333	0.981206569804169	0.61666240586227	0.999999999999841
GO:0005540	hyaluronic acid binding	2/1583	24/18639	0.0833333333333333	0.981206569804169	0.61666240586227	0.999999999999841
GO:0015149	hexose transmembrane transporter activity	2/1583	24/18639	0.0833333333333333	0.981206569804169	0.61666240586227	0.999999999999841
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/1583	24/18639	0.0833333333333333	0.981206569804169	0.61666240586227	0.999999999999841
GO:0019957	C-C chemokine binding	2/1583	24/18639	0.0833333333333333	0.981206569804169	0.61666240586227	0.999999999999841
GO:0042625	ATPase-coupled ion transmembrane transporter activity	2/1583	24/18639	0.0833333333333333	0.981206569804169	0.61666240586227	0.999999999999841
GO:0043998	histone H2A acetyltransferase activity	2/1583	24/18639	0.0833333333333333	0.981206569804169	0.61666240586227	0.999999999999841
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	2/1583	24/18639	0.0833333333333333	0.981206569804169	0.61666240586227	0.999999999999841
GO:0046961	proton-transporting ATPase activity, rotational mechanism	2/1583	24/18639	0.0833333333333333	0.981206569804169	0.61666240586227	0.999999999999841
GO:0055056	D-glucose transmembrane transporter activity	2/1583	24/18639	0.0833333333333333	0.981206569804169	0.61666240586227	0.999999999999841
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/1583	24/18639	0.0833333333333333	0.981206569804169	0.61666240586227	0.999999999999841
GO:0005200	structural constituent of cytoskeleton	9/1583	112/18639	0.0803571428571429	0.946163478025449	0.618526822551915	0.999999999999841
GO:0023023	MHC protein complex binding	3/1583	37/18639	0.0810810810810811	0.954687473322976	0.619007094832508	0.999999999999841
GO:0030551	cyclic nucleotide binding	3/1583	37/18639	0.0810810810810811	0.954687473322976	0.619007094832508	0.999999999999841
GO:0042805	actinin binding	3/1583	37/18639	0.0810810810810811	0.954687473322976	0.619007094832508	0.999999999999841
GO:0001851	complement component C3b binding	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0004016	adenylate cyclase activity	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0005114	type II transforming growth factor beta receptor binding	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0005536	D-glucose binding	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0008172	S-methyltransferase activity	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0008199	ferric iron binding	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0008526	phosphatidylinositol transfer activity	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0015205	nucleobase transmembrane transporter activity	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0019203	carbohydrate phosphatase activity	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0019215	intermediate filament binding	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0034713	type I transforming growth factor beta receptor binding	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0035252	UDP-xylosyltransferase activity	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0042285	xylosyltransferase activity	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0042608	T cell receptor binding	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0045294	alpha-catenin binding	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0047676	arachidonate-CoA ligase activity	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0048185	activin binding	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0050998	nitric-oxide synthase binding	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0070697	activin receptor binding	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0140031	phosphorylation-dependent protein binding	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0140537	transcription regulator activator activity	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:1990948	ubiquitin ligase inhibitor activity	1/1583	11/18639	0.0909090909090909	1.07040716705909	0.62339907504354	0.999999999999841
GO:0004175	endopeptidase activity	33/1583	405/18639	0.0814814814814815	0.959401979364077	0.62566235554139	0.999999999999841
GO:0004721	phosphoprotein phosphatase activity	14/1583	175/18639	0.08	0.941958307012003	0.632500623731758	0.999999999999841
GO:0017022	myosin binding	6/1583	76/18639	0.0789473684210526	0.929564118761845	0.634291244296416	0.999999999999841
GO:0098631	cell adhesion mediator activity	6/1583	76/18639	0.0789473684210526	0.929564118761845	0.634291244296416	0.999999999999841
GO:0140034	methylation-dependent protein binding	6/1583	76/18639	0.0789473684210526	0.929564118761845	0.634291244296416	0.999999999999841
GO:0043531	ADP binding	3/1583	38/18639	0.0789473684210526	0.929564118761845	0.637286683660155	0.999999999999841
GO:0004709	MAP kinase kinase kinase activity	2/1583	25/18639	0.08	0.941958307012003	0.639155901701857	0.999999999999841
GO:0008139	nuclear localization sequence binding	2/1583	25/18639	0.08	0.941958307012003	0.639155901701857	0.999999999999841
GO:0008483	transaminase activity	2/1583	25/18639	0.08	0.941958307012003	0.639155901701857	0.999999999999841
GO:0015645	fatty acid ligase activity	2/1583	25/18639	0.08	0.941958307012003	0.639155901701857	0.999999999999841
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/1583	25/18639	0.08	0.941958307012003	0.639155901701857	0.999999999999841
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/1583	25/18639	0.08	0.941958307012003	0.639155901701857	0.999999999999841
GO:0120515	fatty acid-CoA ligase activity	2/1583	25/18639	0.08	0.941958307012003	0.639155901701857	0.999999999999841
GO:0140767	enzyme-substrate adaptor activity	11/1583	139/18639	0.079136690647482	0.931793289310434	0.641479713510009	0.999999999999841
GO:0042826	histone deacetylase binding	10/1583	127/18639	0.078740157480315	0.927124317925199	0.6455010299579	0.999999999999841
GO:0061134	peptidase regulator activity	18/1583	226/18639	0.079646017699115	0.93779034990133	0.647656572903438	0.999999999999841
GO:1901681	sulfur compound binding	22/1583	275/18639	0.08	0.941958307012003	0.647803468676316	0.999999999999841
GO:0101005	deubiquitinase activity	9/1583	115/18639	0.0782608695652174	0.921480952511742	0.65026069750331	0.999999999999841
GO:0005080	protein kinase C binding	4/1583	52/18639	0.0769230769230769	0.905729141357695	0.654653377111902	0.999999999999841
GO:0031490	chromatin DNA binding	10/1583	128/18639	0.078125	0.919881159191409	0.655318904343854	0.999999999999841
GO:0000340	RNA 7-methylguanosine cap binding	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0003720	telomerase activity	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0003995	acyl-CoA dehydrogenase activity	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0004000	adenosine deaminase activity	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0004126	cytidine deaminase activity	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0005095	GTPase inhibitor activity	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0008179	adenylate cyclase binding	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0008504	monoamine transmembrane transporter activity	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0016801	hydrolase activity, acting on ether bonds	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0016803	ether hydrolase activity	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0016840	carbon-nitrogen lyase activity	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0017166	vinculin binding	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0043047	single-stranded telomeric DNA binding	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0070410	co-SMAD binding	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/1583	12/18639	0.0833333333333333	0.981206569804169	0.655402471232399	0.999999999999841
GO:0004112	cyclic-nucleotide phosphodiesterase activity	2/1583	26/18639	0.0769230769230769	0.905729141357695	0.660596512858989	0.999999999999841
GO:0008143	poly(A) binding	2/1583	26/18639	0.0769230769230769	0.905729141357695	0.660596512858989	0.999999999999841
GO:0015145	monosaccharide transmembrane transporter activity	2/1583	26/18639	0.0769230769230769	0.905729141357695	0.660596512858989	0.999999999999841
GO:0034237	protein kinase A regulatory subunit binding	2/1583	26/18639	0.0769230769230769	0.905729141357695	0.660596512858989	0.999999999999841
GO:0050681	nuclear androgen receptor binding	2/1583	26/18639	0.0769230769230769	0.905729141357695	0.660596512858989	0.999999999999841
GO:0050750	low-density lipoprotein particle receptor binding	2/1583	26/18639	0.0769230769230769	0.905729141357695	0.660596512858989	0.999999999999841
GO:0120014	phospholipid transfer activity	2/1583	26/18639	0.0769230769230769	0.905729141357695	0.660596512858989	0.999999999999841
GO:0042578	phosphoric ester hydrolase activity	29/1583	363/18639	0.0798898071625344	0.940660843779204	0.663565879960775	0.999999999999841
GO:0005543	phospholipid binding	40/1583	497/18639	0.0804828973843058	0.947644172044268	0.664411162904955	0.999999999999841
GO:0035591	signaling adaptor activity	10/1583	129/18639	0.0775193798449612	0.912750297492251	0.664981920979754	0.999999999999841
GO:0004864	protein phosphatase inhibitor activity	4/1583	53/18639	0.0754716981132075	0.888639912275474	0.669527036643533	0.999999999999841
GO:0050997	quaternary ammonium group binding	3/1583	40/18639	0.075	0.883085912823752	0.671972498091922	0.999999999999841
GO:0016298	lipase activity	10/1583	130/18639	0.0769230769230769	0.905729141357695	0.674486902136934	0.999999999999841
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/1583	27/18639	0.0740740740740741	0.872183617603706	0.6810007222179	0.999999999999841
GO:0005104	fibroblast growth factor receptor binding	2/1583	27/18639	0.0740740740740741	0.872183617603706	0.6810007222179	0.999999999999841
GO:0015252	proton channel activity	2/1583	27/18639	0.0740740740740741	0.872183617603706	0.6810007222179	0.999999999999841
GO:0016405	CoA-ligase activity	2/1583	27/18639	0.0740740740740741	0.872183617603706	0.6810007222179	0.999999999999841
GO:0035255	ionotropic glutamate receptor binding	2/1583	27/18639	0.0740740740740741	0.872183617603706	0.6810007222179	0.999999999999841
GO:0050661	NADP binding	4/1583	54/18639	0.0740740740740741	0.872183617603706	0.683953686127753	0.999999999999841
GO:0002161	aminoacyl-tRNA editing activity	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0003964	RNA-directed DNA polymerase activity	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0004993	G protein-coupled serotonin receptor activity	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0005542	folic acid binding	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0008035	high-density lipoprotein particle binding	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0008253	5'-nucleotidase activity	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0017154	semaphorin receptor activity	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0019104	DNA N-glycosylase activity	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0031432	titin binding	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0035325	Toll-like receptor binding	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0035673	oligopeptide transmembrane transporter activity	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0045159	myosin II binding	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0070700	BMP receptor binding	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0071837	HMG box domain binding	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0097157	pre-mRNA intronic binding	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:1901338	catecholamine binding	1/1583	13/18639	0.0769230769230769	0.905729141357695	0.684687803708864	0.999999999999841
GO:0051213	dioxygenase activity	7/1583	93/18639	0.0752688172043011	0.886251095306992	0.685246714575515	0.999999999999841
GO:0030414	peptidase inhibitor activity	13/1583	169/18639	0.0769230769230769	0.905729141357695	0.686188286204053	0.999999999999841
GO:0001618	virus receptor activity	6/1583	81/18639	0.0740740740740741	0.872183617603706	0.695192050221835	0.999999999999841
GO:0005548	phospholipid transporter activity	5/1583	68/18639	0.0735294117647059	0.865770502768385	0.695541473308815	0.999999999999841
GO:0008374	O-acyltransferase activity	4/1583	55/18639	0.0727272727272727	0.856325733647275	0.697931159486457	0.999999999999841
GO:0016866	intramolecular transferase activity	2/1583	28/18639	0.0714285714285714	0.841034202689288	0.700389806222788	0.999999999999841
GO:0046875	ephrin receptor binding	2/1583	28/18639	0.0714285714285714	0.841034202689288	0.700389806222788	0.999999999999841
GO:0050698	proteoglycan sulfotransferase activity	2/1583	28/18639	0.0714285714285714	0.841034202689288	0.700389806222788	0.999999999999841
GO:0051019	mitogen-activated protein kinase binding	2/1583	28/18639	0.0714285714285714	0.841034202689288	0.700389806222788	0.999999999999841
GO:0051119	sugar transmembrane transporter activity	2/1583	28/18639	0.0714285714285714	0.841034202689288	0.700389806222788	0.999999999999841
GO:0051393	alpha-actinin binding	2/1583	28/18639	0.0714285714285714	0.841034202689288	0.700389806222788	0.999999999999841
GO:0140272	exogenous protein binding	6/1583	82/18639	0.0731707317073171	0.861547232023173	0.706521293884686	0.999999999999841
GO:0008276	protein methyltransferase activity	7/1583	95/18639	0.0736842105263158	0.867593177511055	0.706575994293502	0.999999999999841
GO:0002039	p53 binding	5/1583	69/18639	0.072463768115942	0.853223104177539	0.707838523160931	0.999999999999841
GO:0019212	phosphatase inhibitor activity	4/1583	56/18639	0.0714285714285714	0.841034202689288	0.711458906054598	0.999999999999841
GO:0004705	JUN kinase activity	1/1583	14/18639	0.0714285714285714	0.841034202689288	0.711485785386565	0.999999999999841
GO:0008174	mRNA methyltransferase activity	1/1583	14/18639	0.0714285714285714	0.841034202689288	0.711485785386565	0.999999999999841
GO:0008494	translation activator activity	1/1583	14/18639	0.0714285714285714	0.841034202689288	0.711485785386565	0.999999999999841
GO:0015386	potassium:proton antiporter activity	1/1583	14/18639	0.0714285714285714	0.841034202689288	0.711485785386565	0.999999999999841
GO:0019992	diacylglycerol binding	1/1583	14/18639	0.0714285714285714	0.841034202689288	0.711485785386565	0.999999999999841
GO:0034236	protein kinase A catalytic subunit binding	1/1583	14/18639	0.0714285714285714	0.841034202689288	0.711485785386565	0.999999999999841
GO:0043176	amine binding	1/1583	14/18639	0.0714285714285714	0.841034202689288	0.711485785386565	0.999999999999841
GO:0071933	Arp2/3 complex binding	1/1583	14/18639	0.0714285714285714	0.841034202689288	0.711485785386565	0.999999999999841
GO:0098847	sequence-specific single stranded DNA binding	1/1583	14/18639	0.0714285714285714	0.841034202689288	0.711485785386565	0.999999999999841
GO:0004896	cytokine receptor activity	7/1583	96/18639	0.0729166666666667	0.858555748578648	0.71687311899979	0.999999999999841
GO:0140030	modification-dependent protein binding	13/1583	173/18639	0.0751445086705202	0.88478742710665	0.717817402268032	0.999999999999841
GO:0004629	phospholipase C activity	2/1583	29/18639	0.0689655172413793	0.812033023286209	0.718788902768421	0.999999999999841
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	2/1583	29/18639	0.0689655172413793	0.812033023286209	0.718788902768421	0.999999999999841
GO:0106222	lncRNA binding	2/1583	29/18639	0.0689655172413793	0.812033023286209	0.718788902768421	0.999999999999841
GO:0008375	acetylglucosaminyltransferase activity	3/1583	43/18639	0.0697674418604651	0.821475267743025	0.719315580797277	0.999999999999841
GO:0004866	endopeptidase inhibitor activity	12/1583	161/18639	0.0745341614906832	0.87760090715404	0.723265652622016	0.999999999999841
GO:0004527	exonuclease activity	6/1583	84/18639	0.0714285714285714	0.841034202689288	0.728309838840563	0.999999999999841
GO:0008083	growth factor activity	12/1583	162/18639	0.0740740740740741	0.872183617603706	0.731033966989262	0.999999999999841
GO:0004467	long-chain fatty acid-CoA ligase activity	1/1583	15/18639	0.0666666666666667	0.784965255843335	0.736007557291697	0.999999999999841
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/1583	15/18639	0.0666666666666667	0.784965255843335	0.736007557291697	0.999999999999841
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/1583	15/18639	0.0666666666666667	0.784965255843335	0.736007557291697	0.999999999999841
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/1583	15/18639	0.0666666666666667	0.784965255843335	0.736007557291697	0.999999999999841
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/1583	15/18639	0.0666666666666667	0.784965255843335	0.736007557291697	0.999999999999841
GO:0008252	nucleotidase activity	1/1583	15/18639	0.0666666666666667	0.784965255843335	0.736007557291697	0.999999999999841
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/1583	15/18639	0.0666666666666667	0.784965255843335	0.736007557291697	0.999999999999841
GO:0047372	monoacylglycerol lipase activity	1/1583	15/18639	0.0666666666666667	0.784965255843335	0.736007557291697	0.999999999999841
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/1583	15/18639	0.0666666666666667	0.784965255843335	0.736007557291697	0.999999999999841
GO:0141050	histone H3K deacetylase activity	1/1583	15/18639	0.0666666666666667	0.784965255843335	0.736007557291697	0.999999999999841
GO:0141051	histone H4K deacetylase activity	1/1583	15/18639	0.0666666666666667	0.784965255843335	0.736007557291697	0.999999999999841
GO:0001965	G-protein alpha-subunit binding	2/1583	30/18639	0.0666666666666667	0.784965255843335	0.736226202678592	0.999999999999841
GO:0031210	phosphatidylcholine binding	2/1583	30/18639	0.0666666666666667	0.784965255843335	0.736226202678592	0.999999999999841
GO:0070566	adenylyltransferase activity	2/1583	30/18639	0.0666666666666667	0.784965255843335	0.736226202678592	0.999999999999841
GO:0098918	structural constituent of synapse	2/1583	30/18639	0.0666666666666667	0.784965255843335	0.736226202678592	0.999999999999841
GO:0017116	single-stranded DNA helicase activity	4/1583	58/18639	0.0689655172413793	0.812033023286209	0.737170291461068	0.999999999999841
GO:0005518	collagen binding	5/1583	72/18639	0.0694444444444444	0.817672141503474	0.742614917639595	0.999999999999841
GO:0042379	chemokine receptor binding	5/1583	72/18639	0.0694444444444444	0.817672141503474	0.742614917639595	0.999999999999841
GO:0031593	polyubiquitin modification-dependent protein binding	4/1583	59/18639	0.0677966101694915	0.798269751705087	0.749359719078744	0.999999999999841
GO:0005452	solute:inorganic anion antiporter activity	2/1583	31/18639	0.0645161290322581	0.759643795977421	0.752732250523649	0.999999999999841
GO:0070325	lipoprotein particle receptor binding	2/1583	31/18639	0.0645161290322581	0.759643795977421	0.752732250523649	0.999999999999841
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/1583	16/18639	0.0625	0.735904927353127	0.758446347927825	0.999999999999841
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	1/1583	16/18639	0.0625	0.735904927353127	0.758446347927825	0.999999999999841
GO:0004707	MAP kinase activity	1/1583	16/18639	0.0625	0.735904927353127	0.758446347927825	0.999999999999841
GO:0004708	MAP kinase kinase activity	1/1583	16/18639	0.0625	0.735904927353127	0.758446347927825	0.999999999999841
GO:0005149	interleukin-1 receptor binding	1/1583	16/18639	0.0625	0.735904927353127	0.758446347927825	0.999999999999841
GO:0015385	sodium:proton antiporter activity	1/1583	16/18639	0.0625	0.735904927353127	0.758446347927825	0.999999999999841
GO:0015562	efflux transmembrane transporter activity	1/1583	16/18639	0.0625	0.735904927353127	0.758446347927825	0.999999999999841
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/1583	16/18639	0.0625	0.735904927353127	0.758446347927825	0.999999999999841
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/1583	16/18639	0.0625	0.735904927353127	0.758446347927825	0.999999999999841
GO:0034450	ubiquitin-ubiquitin ligase activity	1/1583	16/18639	0.0625	0.735904927353127	0.758446347927825	0.999999999999841
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/1583	16/18639	0.0625	0.735904927353127	0.758446347927825	0.999999999999841
GO:0140328	floppase activity	1/1583	16/18639	0.0625	0.735904927353127	0.758446347927825	0.999999999999841
GO:0008081	phosphoric diester hydrolase activity	6/1583	87/18639	0.0689655172413793	0.812033023286209	0.75881187149018	0.999999999999841
GO:0004714	transmembrane receptor protein tyrosine kinase activity	4/1583	60/18639	0.0666666666666667	0.784965255843335	0.761110752329511	0.999999999999841
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4/1583	60/18639	0.0666666666666667	0.784965255843335	0.761110752329511	0.999999999999841
GO:0003678	DNA helicase activity	5/1583	74/18639	0.0675675675675676	0.795572894435813	0.76404635620248	0.999999999999841
GO:0015106	bicarbonate transmembrane transporter activity	2/1583	32/18639	0.0625	0.735904927353127	0.768339342054875	0.999999999999841
GO:0030515	snoRNA binding	2/1583	32/18639	0.0625	0.735904927353127	0.768339342054875	0.999999999999841
GO:0042910	xenobiotic transmembrane transporter activity	2/1583	32/18639	0.0625	0.735904927353127	0.768339342054875	0.999999999999841
GO:0120015	sterol transfer activity	2/1583	32/18639	0.0625	0.735904927353127	0.768339342054875	0.999999999999841
GO:0019905	syntaxin binding	4/1583	61/18639	0.0655737704918033	0.772096972960658	0.772428995918795	0.999999999999841
GO:0061749	forked DNA-dependent helicase activity	3/1583	47/18639	0.0638297872340425	0.751562478998938	0.773943123794821	0.999999999999841
GO:0004386	helicase activity	11/1583	155/18639	0.0709677419354839	0.835608175575164	0.774819002290355	0.999999999999841
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/1583	17/18639	0.0588235294117647	0.692616402214708	0.778978992036199	0.999999999999841
GO:0008429	phosphatidylethanolamine binding	1/1583	17/18639	0.0588235294117647	0.692616402214708	0.778978992036199	0.999999999999841
GO:0015278	intracellularly gated calcium channel activity	1/1583	17/18639	0.0588235294117647	0.692616402214708	0.778978992036199	0.999999999999841
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/1583	17/18639	0.0588235294117647	0.692616402214708	0.778978992036199	0.999999999999841
GO:0032183	SUMO binding	1/1583	17/18639	0.0588235294117647	0.692616402214708	0.778978992036199	0.999999999999841
GO:0036041	long-chain fatty acid binding	1/1583	17/18639	0.0588235294117647	0.692616402214708	0.778978992036199	0.999999999999841
GO:0045125	bioactive lipid receptor activity	1/1583	17/18639	0.0588235294117647	0.692616402214708	0.778978992036199	0.999999999999841
GO:0046965	nuclear retinoid X receptor binding	1/1583	17/18639	0.0588235294117647	0.692616402214708	0.778978992036199	0.999999999999841
GO:0070402	NADPH binding	1/1583	17/18639	0.0588235294117647	0.692616402214708	0.778978992036199	0.999999999999841
GO:0005125	cytokine activity	17/1583	234/18639	0.0726495726495727	0.855410855726712	0.783653373482432	0.999999999999841
GO:0042393	histone binding	18/1583	247/18639	0.0728744939271255	0.858059186549395	0.78465909570914	0.999999999999841
GO:0036121	double-stranded DNA helicase activity	3/1583	48/18639	0.0625	0.735904927353127	0.786152911521066	0.999999999999841
GO:0005262	calcium channel activity	9/1583	131/18639	0.0687022900763359	0.808933660601911	0.7917825912604	0.999999999999841
GO:0008094	ATP-dependent activity, acting on DNA	15/1583	210/18639	0.0714285714285714	0.841034202689288	0.793938289913458	0.999999999999841
GO:0061135	endopeptidase regulator activity	13/1583	184/18639	0.0706521739130435	0.8318925265731	0.793973015592292	0.999999999999841
GO:0008194	UDP-glycosyltransferase activity	10/1583	145/18639	0.0689655172413793	0.812033023286209	0.796861863008793	0.999999999999841
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/1583	34/18639	0.0588235294117647	0.692616402214708	0.796991566423754	0.999999999999841
GO:0019825	oxygen binding	2/1583	34/18639	0.0588235294117647	0.692616402214708	0.796991566423754	0.999999999999841
GO:0051427	hormone receptor binding	2/1583	34/18639	0.0588235294117647	0.692616402214708	0.796991566423754	0.999999999999841
GO:0090482	vitamin transmembrane transporter activity	2/1583	34/18639	0.0588235294117647	0.692616402214708	0.796991566423754	0.999999999999841
GO:0000400	four-way junction DNA binding	1/1583	18/18639	0.0555555555555556	0.65413771320278	0.797767320658618	0.999999999999841
GO:0000900	mRNA regulatory element binding translation repressor activity	1/1583	18/18639	0.0555555555555556	0.65413771320278	0.797767320658618	0.999999999999841
GO:0008525	phosphatidylcholine transporter activity	1/1583	18/18639	0.0555555555555556	0.65413771320278	0.797767320658618	0.999999999999841
GO:0017075	syntaxin-1 binding	1/1583	18/18639	0.0555555555555556	0.65413771320278	0.797767320658618	0.999999999999841
GO:0034185	apolipoprotein binding	1/1583	18/18639	0.0555555555555556	0.65413771320278	0.797767320658618	0.999999999999841
GO:0035615	clathrin adaptor activity	1/1583	18/18639	0.0555555555555556	0.65413771320278	0.797767320658618	0.999999999999841
GO:0050811	GABA receptor binding	1/1583	18/18639	0.0555555555555556	0.65413771320278	0.797767320658618	0.999999999999841
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/1583	18/18639	0.0555555555555556	0.65413771320278	0.797767320658618	0.999999999999841
GO:0070064	proline-rich region binding	1/1583	18/18639	0.0555555555555556	0.65413771320278	0.797767320658618	0.999999999999841
GO:0005017	platelet-derived growth factor receptor activity	3/1583	50/18639	0.06	0.706468730259002	0.808931712236599	0.999999999999841
GO:0005019	platelet-derived growth factor beta-receptor activity	3/1583	50/18639	0.06	0.706468730259002	0.808931712236599	0.999999999999841
GO:0015085	calcium ion transmembrane transporter activity	10/1583	147/18639	0.0680272108843537	0.800984954942179	0.810260901830606	0.999999999999841
GO:0051219	phosphoprotein binding	6/1583	93/18639	0.0645161290322581	0.759643795977421	0.812099236443643	0.999999999999841
GO:0022821	solute:potassium antiporter activity	1/1583	19/18639	0.0526315789473684	0.619709412507896	0.814959433402155	0.999999999999841
GO:0043395	heparan sulfate proteoglycan binding	1/1583	19/18639	0.0526315789473684	0.619709412507896	0.814959433402155	0.999999999999841
GO:0099589	serotonin receptor activity	1/1583	19/18639	0.0526315789473684	0.619709412507896	0.814959433402155	0.999999999999841
GO:1990380	K48-linked deubiquitinase activity	1/1583	19/18639	0.0526315789473684	0.619709412507896	0.814959433402155	0.999999999999841
GO:0005021	vascular endothelial growth factor receptor activity	3/1583	51/18639	0.0588235294117647	0.692616402214708	0.819531405057459	0.999999999999841
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/1583	36/18639	0.0555555555555556	0.65413771320278	0.822458415379137	0.999999999999841
GO:0016409	palmitoyltransferase activity	2/1583	36/18639	0.0555555555555556	0.65413771320278	0.822458415379137	0.999999999999841
GO:0004620	phospholipase activity	7/1583	109/18639	0.0642201834862385	0.756159191408718	0.828388425774079	0.999999999999841
GO:0030159	signaling receptor complex adaptor activity	3/1583	52/18639	0.0576923076923077	0.679296856018271	0.829625978196983	0.999999999999841
GO:0001614	purinergic nucleotide receptor activity	1/1583	20/18639	0.05	0.588723941882502	0.83069086288252	0.999999999999841
GO:0005326	neurotransmitter transmembrane transporter activity	1/1583	20/18639	0.05	0.588723941882502	0.83069086288252	0.999999999999841
GO:0016502	nucleotide receptor activity	1/1583	20/18639	0.05	0.588723941882502	0.83069086288252	0.999999999999841
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/1583	20/18639	0.05	0.588723941882502	0.83069086288252	0.999999999999841
GO:0140939	histone H4 methyltransferase activity	1/1583	20/18639	0.05	0.588723941882502	0.83069086288252	0.999999999999841
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	4/1583	67/18639	0.0597014925373134	0.702953960456718	0.831662480828777	0.999999999999841
GO:0050840	extracellular matrix binding	4/1583	67/18639	0.0597014925373134	0.702953960456718	0.831662480828777	0.999999999999841
GO:0017046	peptide hormone binding	3/1583	53/18639	0.0566037735849057	0.666479934206606	0.83923191469019	0.999999999999841
GO:0030165	PDZ domain binding	5/1583	83/18639	0.0602409638554217	0.709305954075303	0.843959596582359	0.999999999999841
GO:0042162	telomeric DNA binding	2/1583	38/18639	0.0526315789473684	0.619709412507896	0.845017400761576	0.999999999999841
GO:0042887	amide transmembrane transporter activity	2/1583	38/18639	0.0526315789473684	0.619709412507896	0.845017400761576	0.999999999999841
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/1583	21/18639	0.0476190476190476	0.560689468459525	0.845085640478361	0.999999999999841
GO:0008373	sialyltransferase activity	1/1583	21/18639	0.0476190476190476	0.560689468459525	0.845085640478361	0.999999999999841
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/1583	21/18639	0.0476190476190476	0.560689468459525	0.845085640478361	0.999999999999841
GO:0019200	carbohydrate kinase activity	1/1583	21/18639	0.0476190476190476	0.560689468459525	0.845085640478361	0.999999999999841
GO:0036122	BMP binding	1/1583	21/18639	0.0476190476190476	0.560689468459525	0.845085640478361	0.999999999999841
GO:0051010	microtubule plus-end binding	1/1583	21/18639	0.0476190476190476	0.560689468459525	0.845085640478361	0.999999999999841
GO:0051428	peptide hormone receptor binding	1/1583	21/18639	0.0476190476190476	0.560689468459525	0.845085640478361	0.999999999999841
GO:0070182	DNA polymerase binding	1/1583	21/18639	0.0476190476190476	0.560689468459525	0.845085640478361	0.999999999999841
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	3/1583	54/18639	0.0555555555555556	0.65413771320278	0.848365928135039	0.999999999999841
GO:0004713	protein tyrosine kinase activity	9/1583	140/18639	0.0642857142857143	0.756930782420359	0.850208289491979	0.999999999999841
GO:0051015	actin filament binding	14/1583	209/18639	0.0669856459330144	0.788721070464595	0.857034089381457	0.999999999999841
GO:0004407	histone deacetylase activity	1/1583	22/18639	0.0454545454545455	0.535203583529547	0.858257271755768	0.999999999999841
GO:0005243	gap junction channel activity	1/1583	22/18639	0.0454545454545455	0.535203583529547	0.858257271755768	0.999999999999841
GO:0016881	acid-amino acid ligase activity	1/1583	22/18639	0.0454545454545455	0.535203583529547	0.858257271755768	0.999999999999841
GO:0033558	protein lysine deacetylase activity	1/1583	22/18639	0.0454545454545455	0.535203583529547	0.858257271755768	0.999999999999841
GO:0050321	tau-protein kinase activity	1/1583	22/18639	0.0454545454545455	0.535203583529547	0.858257271755768	0.999999999999841
GO:0061133	endopeptidase activator activity	1/1583	22/18639	0.0454545454545455	0.535203583529547	0.858257271755768	0.999999999999841
GO:0140035	ubiquitin-like protein reader activity	1/1583	22/18639	0.0454545454545455	0.535203583529547	0.858257271755768	0.999999999999841
GO:0140299	molecular sensor activity	4/1583	71/18639	0.0563380281690141	0.663350920430988	0.863549713357041	0.999999999999841
GO:0015144	carbohydrate transmembrane transporter activity	2/1583	40/18639	0.05	0.588723941882502	0.864940080156923	0.999999999999841
GO:0030170	pyridoxal phosphate binding	3/1583	56/18639	0.0535714285714286	0.630775652016966	0.865285571305398	0.999999999999841
GO:0035401	histone H3Y41 kinase activity	7/1583	115/18639	0.0608695652173913	0.716707407509132	0.866612457521725	0.999999999999841
GO:0140801	histone H2AXY142 kinase activity	7/1583	115/18639	0.0608695652173913	0.716707407509132	0.866612457521725	0.999999999999841
GO:0017171	serine hydrolase activity	13/1583	198/18639	0.0656565656565657	0.773071842876012	0.867991735508128	0.999999999999841
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/1583	23/18639	0.0434782608695652	0.511933862506523	0.870309629214576	0.999999999999841
GO:0016493	C-C chemokine receptor activity	1/1583	23/18639	0.0434782608695652	0.511933862506523	0.870309629214576	0.999999999999841
GO:0042171	lysophosphatidic acid acyltransferase activity	1/1583	23/18639	0.0434782608695652	0.511933862506523	0.870309629214576	0.999999999999841
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/1583	23/18639	0.0434782608695652	0.511933862506523	0.870309629214576	0.999999999999841
GO:0070577	lysine-acetylated histone binding	1/1583	23/18639	0.0434782608695652	0.511933862506523	0.870309629214576	0.999999999999841
GO:0071617	lysophospholipid acyltransferase activity	1/1583	23/18639	0.0434782608695652	0.511933862506523	0.870309629214576	0.999999999999841
GO:0019903	protein phosphatase binding	9/1583	144/18639	0.0625	0.735904927353127	0.871626008944382	0.999999999999841
GO:0070279	vitamin B6 binding	3/1583	57/18639	0.0526315789473684	0.619709412507896	0.873104888809627	0.999999999999841
GO:0004812	aminoacyl-tRNA ligase activity	2/1583	41/18639	0.0487804878048781	0.574364821348782	0.873994667628768	0.999999999999841
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	2/1583	41/18639	0.0487804878048781	0.574364821348782	0.873994667628768	0.999999999999841
GO:0008227	G protein-coupled amine receptor activity	2/1583	41/18639	0.0487804878048781	0.574364821348782	0.873994667628768	0.999999999999841
GO:0015175	neutral L-amino acid transmembrane transporter activity	2/1583	41/18639	0.0487804878048781	0.574364821348782	0.873994667628768	0.999999999999841
GO:0016875	ligase activity, forming carbon-oxygen bonds	2/1583	41/18639	0.0487804878048781	0.574364821348782	0.873994667628768	0.999999999999841
GO:0019208	phosphatase regulator activity	7/1583	117/18639	0.0598290598290598	0.704455998833763	0.877687241493622	0.999999999999841
GO:0005253	monoatomic anion channel activity	6/1583	103/18639	0.058252427184466	0.685891971125245	0.879847048424204	0.999999999999841
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/1583	24/18639	0.0416666666666667	0.490603284902085	0.881337769360328	0.999999999999841
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/1583	24/18639	0.0416666666666667	0.490603284902085	0.881337769360328	0.999999999999841
GO:0004806	triacylglycerol lipase activity	1/1583	24/18639	0.0416666666666667	0.490603284902085	0.881337769360328	0.999999999999841
GO:0005315	phosphate transmembrane transporter activity	1/1583	24/18639	0.0416666666666667	0.490603284902085	0.881337769360328	0.999999999999841
GO:0015295	solute:proton symporter activity	1/1583	24/18639	0.0416666666666667	0.490603284902085	0.881337769360328	0.999999999999841
GO:0030215	semaphorin receptor binding	1/1583	24/18639	0.0416666666666667	0.490603284902085	0.881337769360328	0.999999999999841
GO:0030552	cAMP binding	1/1583	24/18639	0.0416666666666667	0.490603284902085	0.881337769360328	0.999999999999841
GO:0050431	transforming growth factor beta binding	1/1583	24/18639	0.0416666666666667	0.490603284902085	0.881337769360328	0.999999999999841
GO:0050699	WW domain binding	1/1583	24/18639	0.0416666666666667	0.490603284902085	0.881337769360328	0.999999999999841
GO:0070840	dynein complex binding	1/1583	24/18639	0.0416666666666667	0.490603284902085	0.881337769360328	0.999999999999841
GO:0140033	acetylation-dependent protein binding	1/1583	24/18639	0.0416666666666667	0.490603284902085	0.881337769360328	0.999999999999841
GO:0008307	structural constituent of muscle	2/1583	42/18639	0.0476190476190476	0.560689468459525	0.882486654018894	0.999999999999841
GO:0003684	damaged DNA binding	4/1583	74/18639	0.0540540540540541	0.63645831554865	0.883935860277663	0.999999999999841
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	16/1583	243/18639	0.065843621399177	0.77527432675885	0.886186543754407	0.999999999999841
GO:0045309	protein phosphorylated amino acid binding	3/1583	59/18639	0.0508474576271186	0.598702313778815	0.887545920217513	0.999999999999841
GO:0005085	guanyl-nucleotide exchange factor activity	15/1583	230/18639	0.0652173913043478	0.767900793759785	0.887963467484031	0.999999999999841
GO:0005245	voltage-gated calcium channel activity	2/1583	43/18639	0.0465116279069767	0.54765017849535	0.89044621856629	0.999999999999841
GO:0008200	ion channel inhibitor activity	2/1583	43/18639	0.0465116279069767	0.54765017849535	0.89044621856629	0.999999999999841
GO:0048156	tau protein binding	2/1583	43/18639	0.0465116279069767	0.54765017849535	0.89044621856629	0.999999999999841
GO:0004252	serine-type endopeptidase activity	11/1583	176/18639	0.0625	0.735904927353127	0.890738037144545	0.999999999999841
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/1583	25/18639	0.04	0.470979153506001	0.891428680512764	0.999999999999841
GO:0042974	nuclear retinoic acid receptor binding	1/1583	25/18639	0.04	0.470979153506001	0.891428680512764	0.999999999999841
GO:0120020	cholesterol transfer activity	1/1583	25/18639	0.04	0.470979153506001	0.891428680512764	0.999999999999841
GO:0019902	phosphatase binding	12/1583	190/18639	0.0631578947368421	0.743651295009476	0.891468231037877	0.999999999999841
GO:0004676	3-phosphoinositide-dependent protein kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0004711	ribosomal protein S6 kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0035175	histone H3S10 kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0035979	histone H2AXS139 kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0044022	histone H3S28 kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0044023	histone H4S1 kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0044024	histone H2AS1 kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0044025	histone H2BS14 kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0072354	histone H3T3 kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0072371	histone H2AS121 kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0072518	Rho-dependent protein serine/threonine kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0140823	histone H2BS36 kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0140855	histone H3S57 kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0140995	histone H2A kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0140997	histone H4 kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0140998	histone H2B kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:1990244	histone H2AT120 kinase activity	16/1583	245/18639	0.0653061224489796	0.768945556744492	0.893218177171218	0.999999999999841
GO:0008013	beta-catenin binding	6/1583	106/18639	0.0566037735849057	0.666479934206606	0.895653143801229	0.999999999999841
GO:0015297	antiporter activity	8/1583	135/18639	0.0592592592592593	0.697746894082965	0.895757478108908	0.999999999999841
GO:0004677	DNA-dependent protein kinase activity	16/1583	246/18639	0.0650406504065041	0.765819761798376	0.896600405865977	0.999999999999841
GO:0140857	histone H3T45 kinase activity	16/1583	246/18639	0.0650406504065041	0.765819761798376	0.896600405865977	0.999999999999841
GO:0001223	transcription coactivator binding	2/1583	44/18639	0.0454545454545455	0.535203583529547	0.897902475932544	0.999999999999841
GO:0016248	channel inhibitor activity	2/1583	44/18639	0.0454545454545455	0.535203583529547	0.897902475932544	0.999999999999841
GO:0019842	vitamin binding	9/1583	150/18639	0.06	0.706468730259002	0.89902279114705	0.999999999999841
GO:0035402	histone H3T11 kinase activity	16/1583	247/18639	0.0647773279352227	0.762719276932796	0.899895398216594	0.999999999999841
GO:0035403	histone H3T6 kinase activity	16/1583	247/18639	0.0647773279352227	0.762719276932796	0.899895398216594	0.999999999999841
GO:0019888	protein phosphatase regulator activity	6/1583	107/18639	0.0560747663551402	0.660251149774768	0.900511335851095	0.999999999999841
GO:0001637	G protein-coupled chemoattractant receptor activity	1/1583	26/18639	0.0384615384615385	0.452864570678847	0.900661967218915	0.999999999999841
GO:0004435	phosphatidylinositol phospholipase C activity	1/1583	26/18639	0.0384615384615385	0.452864570678847	0.900661967218915	0.999999999999841
GO:0004950	chemokine receptor activity	1/1583	26/18639	0.0384615384615385	0.452864570678847	0.900661967218915	0.999999999999841
GO:0005112	Notch binding	1/1583	26/18639	0.0384615384615385	0.452864570678847	0.900661967218915	0.999999999999841
GO:0008157	protein phosphatase 1 binding	1/1583	26/18639	0.0384615384615385	0.452864570678847	0.900661967218915	0.999999999999841
GO:0019865	immunoglobulin binding	1/1583	26/18639	0.0384615384615385	0.452864570678847	0.900661967218915	0.999999999999841
GO:0030507	spectrin binding	1/1583	26/18639	0.0384615384615385	0.452864570678847	0.900661967218915	0.999999999999841
GO:0043548	phosphatidylinositol 3-kinase binding	1/1583	26/18639	0.0384615384615385	0.452864570678847	0.900661967218915	0.999999999999841
GO:0051139	metal cation:proton antiporter activity	1/1583	26/18639	0.0384615384615385	0.452864570678847	0.900661967218915	0.999999999999841
GO:0070412	R-SMAD binding	1/1583	26/18639	0.0384615384615385	0.452864570678847	0.900661967218915	0.999999999999841
GO:0051020	GTPase binding	21/1583	315/18639	0.0666666666666667	0.784965255843335	0.90235045579926	0.999999999999841
GO:0004679	AMP-activated protein kinase activity	16/1583	248/18639	0.0645161290322581	0.759643795977421	0.903104544349255	0.999999999999841
GO:0004715	non-membrane spanning protein tyrosine kinase activity	2/1583	45/18639	0.0444444444444444	0.523310170562224	0.90488343926289	0.999999999999841
GO:0141110	transporter inhibitor activity	2/1583	45/18639	0.0444444444444444	0.523310170562224	0.90488343926289	0.999999999999841
GO:0004843	cysteine-type deubiquitinase activity	6/1583	108/18639	0.0555555555555556	0.65413771320278	0.905173996275239	0.999999999999841
GO:0008236	serine-type peptidase activity	12/1583	194/18639	0.0618556701030928	0.728318278617528	0.906189275585514	0.999999999999841
GO:0019199	transmembrane receptor protein kinase activity	4/1583	78/18639	0.0512820512820513	0.603819427571797	0.90695694504976	0.999999999999841
GO:0005044	scavenger receptor activity	1/1583	27/18639	0.037037037037037	0.436091808801853	0.909110476642031	0.999999999999841
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	1/1583	27/18639	0.037037037037037	0.436091808801853	0.909110476642031	0.999999999999841
GO:0030276	clathrin binding	2/1583	46/18639	0.0434782608695652	0.511933862506523	0.911415997188789	0.999999999999841
GO:0015631	tubulin binding	26/1583	385/18639	0.0675324675324675	0.795159609815327	0.91178289562659	0.999999999999841
GO:0033293	monocarboxylic acid binding	4/1583	79/18639	0.0506329113924051	0.596176143678483	0.912039168214935	0.999999999999841
GO:0004867	serine-type endopeptidase inhibitor activity	5/1583	95/18639	0.0526315789473684	0.619709412507896	0.914455214356971	0.999999999999841
GO:0005242	inward rectifier potassium channel activity	1/1583	28/18639	0.0357142857142857	0.420517101344644	0.916840871842744	0.999999999999841
GO:0045499	chemorepellent activity	1/1583	28/18639	0.0357142857142857	0.420517101344644	0.916840871842744	0.999999999999841
GO:0001784	phosphotyrosine residue binding	2/1583	47/18639	0.0425531914893617	0.501041652665959	0.917525902672966	0.999999999999841
GO:0030971	receptor tyrosine kinase binding	4/1583	81/18639	0.0493827160493827	0.581455745069137	0.921467030257809	0.999999999999841
GO:0120013	lipid transfer activity	3/1583	65/18639	0.0461538461538462	0.543437484814617	0.922440645206618	0.999999999999841
GO:0016879	ligase activity, forming carbon-nitrogen bonds	2/1583	48/18639	0.0416666666666667	0.490603284902085	0.923237771853483	0.999999999999841
GO:0038187	pattern recognition receptor activity	2/1583	48/18639	0.0416666666666667	0.490603284902085	0.923237771853483	0.999999999999841
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/1583	29/18639	0.0344827586206897	0.406016511643104	0.923914156452541	0.999999999999841
GO:0043236	laminin binding	1/1583	29/18639	0.0344827586206897	0.406016511643104	0.923914156452541	0.999999999999841
GO:0051861	glycolipid binding	1/1583	29/18639	0.0344827586206897	0.406016511643104	0.923914156452541	0.999999999999841
GO:0097472	cyclin-dependent protein kinase activity	1/1583	29/18639	0.0344827586206897	0.406016511643104	0.923914156452541	0.999999999999841
GO:0099604	ligand-gated calcium channel activity	1/1583	29/18639	0.0344827586206897	0.406016511643104	0.923914156452541	0.999999999999841
GO:0008514	organic anion transmembrane transporter activity	17/1583	269/18639	0.0631970260223048	0.744112045502047	0.92397692180295	0.999999999999841
GO:0005004	GPI-linked ephrin receptor activity	2/1583	49/18639	0.0408163265306122	0.480590972965307	0.928575091270804	0.999999999999841
GO:0005008	hepatocyte growth factor receptor activity	2/1583	49/18639	0.0408163265306122	0.480590972965307	0.928575091270804	0.999999999999841
GO:0005009	insulin receptor activity	2/1583	49/18639	0.0408163265306122	0.480590972965307	0.928575091270804	0.999999999999841
GO:0005011	macrophage colony-stimulating factor receptor activity	2/1583	49/18639	0.0408163265306122	0.480590972965307	0.928575091270804	0.999999999999841
GO:0005018	platelet-derived growth factor alpha-receptor activity	2/1583	49/18639	0.0408163265306122	0.480590972965307	0.928575091270804	0.999999999999841
GO:0005020	stem cell factor receptor activity	2/1583	49/18639	0.0408163265306122	0.480590972965307	0.928575091270804	0.999999999999841
GO:0008288	boss receptor activity	2/1583	49/18639	0.0408163265306122	0.480590972965307	0.928575091270804	0.999999999999841
GO:0036332	placental growth factor receptor activity	2/1583	49/18639	0.0408163265306122	0.480590972965307	0.928575091270804	0.999999999999841
GO:0038062	protein tyrosine kinase collagen receptor activity	2/1583	49/18639	0.0408163265306122	0.480590972965307	0.928575091270804	0.999999999999841
GO:0060175	brain-derived neurotrophic factor receptor activity	2/1583	49/18639	0.0408163265306122	0.480590972965307	0.928575091270804	0.999999999999841
GO:0001540	amyloid-beta binding	4/1583	83/18639	0.0481927710843374	0.567444763260243	0.929977702283642	0.999999999999841
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/1583	30/18639	0.0333333333333333	0.392482627921668	0.930386154858539	0.999999999999841
GO:0051721	protein phosphatase 2A binding	1/1583	30/18639	0.0333333333333333	0.392482627921668	0.930386154858539	0.999999999999841
GO:0016500	protein-hormone receptor activity	3/1583	67/18639	0.0447761194029851	0.527215470342539	0.931664037460926	0.999999999999841
GO:0005006	epidermal growth factor receptor activity	2/1583	50/18639	0.04	0.470979153506001	0.933560232063896	0.999999999999841
GO:0005007	fibroblast growth factor receptor activity	2/1583	50/18639	0.04	0.470979153506001	0.933560232063896	0.999999999999841
GO:0048020	CCR chemokine receptor binding	2/1583	50/18639	0.04	0.470979153506001	0.933560232063896	0.999999999999841
GO:0016411	acylglycerol O-acyltransferase activity	1/1583	31/18639	0.032258064516129	0.379821897988711	0.936307951669702	0.999999999999841
GO:0072349	modified amino acid transmembrane transporter activity	1/1583	31/18639	0.032258064516129	0.379821897988711	0.936307951669702	0.999999999999841
GO:0060589	nucleoside-triphosphatase regulator activity	33/1583	490/18639	0.0673469387755102	0.792975105392757	0.936703530695565	0.999999999999841
GO:0005010	insulin-like growth factor receptor activity	2/1583	51/18639	0.0392156862745098	0.461744268143138	0.938214469900894	0.999999999999841
GO:0005030	neurotrophin receptor activity	2/1583	51/18639	0.0392156862745098	0.461744268143138	0.938214469900894	0.999999999999841
GO:0071813	lipoprotein particle binding	1/1583	32/18639	0.03125	0.367952463676563	0.941726293915342	0.999999999999841
GO:0071814	protein-lipid complex binding	1/1583	32/18639	0.03125	0.367952463676563	0.941726293915342	0.999999999999841
GO:0005319	lipid transporter activity	10/1583	178/18639	0.0561797752808989	0.661487575148878	0.942788393577862	0.999999999999841
GO:0008028	monocarboxylic acid transmembrane transporter activity	3/1583	70/18639	0.0428571428571429	0.504620521613573	0.943618078016749	0.999999999999841
GO:0016278	lysine N-methyltransferase activity	3/1583	70/18639	0.0428571428571429	0.504620521613573	0.943618078016749	0.999999999999841
GO:0097110	scaffold protein binding	3/1583	70/18639	0.0428571428571429	0.504620521613573	0.943618078016749	0.999999999999841
GO:0106310	protein serine kinase activity	23/1583	361/18639	0.0637119113573407	0.750174551983243	0.944996010409765	0.999999999999841
GO:0005003	ephrin receptor activity	2/1583	53/18639	0.0377358490566038	0.444319956137737	0.94661001328979	0.999999999999841
GO:0005005	transmembrane-ephrin receptor activity	2/1583	53/18639	0.0377358490566038	0.444319956137737	0.94661001328979	0.999999999999841
GO:0038064	collagen receptor activity	2/1583	53/18639	0.0377358490566038	0.444319956137737	0.94661001328979	0.999999999999841
GO:0051018	protein kinase A binding	2/1583	53/18639	0.0377358490566038	0.444319956137737	0.94661001328979	0.999999999999841
GO:0030296	protein tyrosine kinase activator activity	1/1583	33/18639	0.0303030303030303	0.356802389019698	0.946683959134454	0.999999999999841
GO:0030695	GTPase regulator activity	32/1583	489/18639	0.065439672801636	0.770518042545605	0.954644268102621	0.999999999999841
GO:0034061	DNA polymerase activity	1/1583	35/18639	0.0285714285714286	0.336413681075715	0.955370513852551	0.999999999999841
GO:0005539	glycosaminoglycan binding	14/1583	242/18639	0.0578512396694215	0.681168197219423	0.955620206677603	0.999999999999841
GO:0004190	aspartic-type endopeptidase activity	1/1583	36/18639	0.0277777777777778	0.32706885660139	0.959168002380363	0.999999999999841
GO:0140375	immune receptor activity	8/1583	156/18639	0.0512820512820513	0.603819427571797	0.959807448554227	0.999999999999841
GO:0008201	heparin binding	9/1583	172/18639	0.0523255813953488	0.616106450807269	0.961342920095025	0.999999999999841
GO:0031406	carboxylic acid binding	10/1583	187/18639	0.053475935828877	0.629651274740643	0.961349295868273	0.999999999999841
GO:0030280	structural constituent of skin epidermis	1/1583	37/18639	0.027027027027027	0.318229157774325	0.962642552304133	0.999999999999841
GO:0070001	aspartic-type peptidase activity	1/1583	37/18639	0.027027027027027	0.318229157774325	0.962642552304133	0.999999999999841
GO:0005244	voltage-gated monoatomic ion channel activity	9/1583	173/18639	0.0520231213872832	0.612545141843065	0.963094564764426	0.999999999999841
GO:0003779	actin binding	28/1583	443/18639	0.0632054176072235	0.744210852041086	0.964129508197702	0.999999999999841
GO:0043177	organic acid binding	10/1583	189/18639	0.0529100529100529	0.622988298288361	0.964659794258452	0.999999999999841
GO:0036002	pre-mRNA binding	2/1583	59/18639	0.0338983050847458	0.399134875852543	0.965749769192481	0.999999999999841
GO:0001653	peptide receptor activity	6/1583	128/18639	0.046875	0.551928695514845	0.965859573176329	0.999999999999841
GO:0022832	voltage-gated channel activity	9/1583	175/18639	0.0514285714285714	0.605544625936287	0.966385473953462	0.999999999999841
GO:0001217	DNA-binding transcription repressor activity	16/1583	278/18639	0.0575539568345324	0.677667846771225	0.966576713275535	0.999999999999841
GO:0140097	catalytic activity, acting on DNA	20/1583	336/18639	0.0595238095238095	0.700861835574407	0.968114751219265	0.999999999999841
GO:0000217	DNA secondary structure binding	1/1583	39/18639	0.0256410256410256	0.301909713785898	0.968730292280254	0.999999999999841
GO:0032451	demethylase activity	1/1583	40/18639	0.025	0.294361970941251	0.971391579770596	0.999999999999841
GO:0071855	neuropeptide receptor binding	1/1583	40/18639	0.025	0.294361970941251	0.971391579770596	0.999999999999841
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	15/1583	268/18639	0.0559701492537313	0.659019337928173	0.971852855158199	0.999999999999841
GO:0141003	histone H2AX kinase activity	21/1583	354/18639	0.0593220338983051	0.698486032741951	0.972240166650404	0.999999999999841
GO:0031267	small GTPase binding	16/1583	283/18639	0.0565371024734982	0.665694916616256	0.972435622903624	0.999999999999841
GO:0015179	L-amino acid transmembrane transporter activity	2/1583	62/18639	0.032258064516129	0.379821897988711	0.972647696012832	0.999999999999841
GO:0015101	organic cation transmembrane transporter activity	3/1583	81/18639	0.037037037037037	0.436091808801853	0.972739039167234	0.999999999999841
GO:0017080	sodium channel regulator activity	1/1583	41/18639	0.024390243902439	0.287182410674391	0.973826502574142	0.999999999999841
GO:0140828	metal cation:monoatomic cation antiporter activity	1/1583	41/18639	0.024390243902439	0.287182410674391	0.973826502574142	0.999999999999841
GO:0008509	monoatomic anion transmembrane transporter activity	7/1583	149/18639	0.0469798657718121	0.55316343532584	0.973857090733418	0.999999999999841
GO:1901682	sulfur compound transmembrane transporter activity	2/1583	63/18639	0.0317460317460317	0.373792978973017	0.97463318471372	0.999999999999841
GO:0140996	histone H3 kinase activity	21/1583	357/18639	0.0588235294117647	0.692616402214708	0.975035176209758	0.999999999999841
GO:0005096	GTPase activator activity	15/1583	271/18639	0.0553505535055351	0.651723920903138	0.975039775443725	0.999999999999841
GO:0019894	kinesin binding	1/1583	42/18639	0.0238095238095238	0.280344734229763	0.976054303758416	0.999999999999841
GO:0005254	chloride channel activity	3/1583	83/18639	0.036144578313253	0.425583572445182	0.976190657362462	0.999999999999841
GO:0035173	histone kinase activity	21/1583	360/18639	0.0583333333333333	0.686844598862919	0.977576976892908	0.999999999999841
GO:0038024	cargo receptor activity	2/1583	65/18639	0.0307692307692308	0.362291656543078	0.97819449020699	0.999999999999841
GO:0003774	cytoskeletal motor activity	7/1583	153/18639	0.0457516339869281	0.538701646166995	0.978824436083284	0.999999999999841
GO:0008528	G protein-coupled peptide receptor activity	5/1583	122/18639	0.040983606557377	0.482560608100411	0.981164137929104	0.999999999999841
GO:0042054	histone methyltransferase activity	2/1583	67/18639	0.0298507462686567	0.351476980228359	0.981269246927966	0.999999999999841
GO:0030246	carbohydrate binding	15/1583	280/18639	0.0535714285714286	0.630775652016966	0.982747801550407	0.999999999999841
GO:0005267	potassium channel activity	5/1583	124/18639	0.0403225806451613	0.474777372485888	0.983282090086556	0.999999999999841
GO:0016279	protein-lysine N-methyltransferase activity	2/1583	69/18639	0.0289855072463768	0.341289241671015	0.983921397706804	0.999999999999841
GO:0008188	neuropeptide receptor activity	1/1583	48/18639	0.0208333333333333	0.245301642451042	0.985959709456151	0.999999999999841
GO:0015103	inorganic anion transmembrane transporter activity	7/1583	165/18639	0.0424242424242424	0.499523344627577	0.988968425026518	0.999999999999841
GO:0016597	amino acid binding	1/1583	51/18639	0.0196078431372549	0.230872134071569	0.989249688201584	0.999999999999841
GO:0003730	mRNA 3'-UTR binding	13/1583	262/18639	0.049618320610687	0.584229865990269	0.989850106417684	0.999999999999841
GO:0017124	SH3 domain binding	4/1583	115/18639	0.0347826086956522	0.409547090005218	0.990355424968502	0.999999999999841
GO:1990782	protein tyrosine kinase binding	4/1583	117/18639	0.0341880341880342	0.402546285047864	0.991543181389744	0.999999999999841
GO:0005249	voltage-gated potassium channel activity	3/1583	98/18639	0.0306122448979592	0.360443229723981	0.991599534269514	0.999999999999841
GO:0004674	protein serine/threonine kinase activity	24/1583	433/18639	0.0554272517321016	0.652627002548732	0.992610200141199	0.999999999999841
GO:0015291	secondary active transmembrane transporter activity	14/1583	287/18639	0.0487804878048781	0.574364821348782	0.993474188121879	0.999999999999841
GO:0015079	potassium ion transmembrane transporter activity	6/1583	160/18639	0.0375	0.441542956411876	0.994526542560331	0.999999999999841
GO:0008017	microtubule binding	13/1583	276/18639	0.0471014492753623	0.5545950177154	0.994734619498642	0.999999999999841
GO:0022843	voltage-gated monoatomic cation channel activity	5/1583	143/18639	0.034965034965035	0.411695064253498	0.994825721840014	0.999999999999841
GO:0005261	monoatomic cation channel activity	17/1583	341/18639	0.0498533724340176	0.586997478709826	0.995449575842255	0.999999999999841
GO:0015293	symporter activity	5/1583	146/18639	0.0342465753424658	0.40323557663185	0.995725775046957	0.999999999999841
GO:0046873	metal ion transmembrane transporter activity	24/1583	450/18639	0.0533333333333333	0.627972204674668	0.996186618233821	0.999999999999841
GO:0003823	antigen binding	6/1583	174/18639	0.0344827586206897	0.406016511643104	0.997682501086725	0.999999999999841
GO:0015294	solute:monoatomic cation symporter activity	3/1583	116/18639	0.0258620689655172	0.304512383732328	0.997711374626474	0.999999999999841
GO:0005216	monoatomic ion channel activity	23/1583	448/18639	0.0513392857142857	0.604493333182926	0.99774464278874	0.999999999999841
GO:0015108	chloride transmembrane transporter activity	3/1583	121/18639	0.0247933884297521	0.291929227379753	0.998417693137237	0.999999999999841
GO:0015171	amino acid transmembrane transporter activity	2/1583	102/18639	0.0196078431372549	0.230872134071569	0.998799579344242	0.999999999999841
GO:0099094	ligand-gated monoatomic cation channel activity	3/1583	136/18639	0.0220588235294118	0.259731150830515	0.999485897124831	0.999999999999841
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	23/1583	484/18639	0.0475206611570248	0.559531019144526	0.999531036730104	0.999999999999841
GO:0001216	DNA-binding transcription activator activity	23/1583	491/18639	0.0468431771894094	0.551553998504991	0.99965938447612	0.999999999999841
GO:0046943	carboxylic acid transmembrane transporter activity	5/1583	188/18639	0.0265957446808511	0.313151032916224	0.99974232793233	0.999999999999841
GO:0005342	organic acid transmembrane transporter activity	5/1583	189/18639	0.0264550264550265	0.311494149144181	0.99975961727069	0.999999999999841
GO:0030594	neurotransmitter receptor activity	1/1583	97/18639	0.0103092783505155	0.121386379769588	0.999821766705737	0.999999999999841
GO:0022836	gated channel activity	11/1583	318/18639	0.0345911949685535	0.407293293126259	0.999910598696224	0.999999999999841
GO:0015276	ligand-gated monoatomic ion channel activity	3/1583	186/18639	0.0161290322580645	0.189910948994355	0.999989454312053	0.999999999999841
GO:0022834	ligand-gated channel activity	3/1583	188/18639	0.0159574468085106	0.187890619749735	0.999991004011568	0.999999999999841
GO:0005179	hormone activity	1/1583	132/18639	0.00757575757575758	0.0892005972549245	0.999992179860169	0.999999999999841
GO:0015081	sodium ion transmembrane transporter activity	1/1583	164/18639	0.00609756097560976	0.0717956026685978	0.999999553862983	0.999999999999841
GO:0045182	translation regulator activity	2/1583	356/18639	0.00561797752808989	0.0661487575148878	0.999999999999521	0.999999999999841
GO:0030371	translation repressor activity	1/1583	329/18639	0.00303951367781155	0.0357886894761399	0.999999999999841	0.999999999999841