category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	14/146	300/9376	2.99689497716895	KIT/TNF/PTPN7/PRKCA/HSPA1A/TP53/CSF1/DUSP6/LAMTOR3/RPS6KA1/PAK1/PPP3R1/TAOK3/ARRB1	4.42109476430593
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	11/146	216/9376	3.27042110603754	TNF/PRKCA/HSPA1A/TP53/HSP90AA1/MIB2/CASP7/HSP90AB1/HSPD1/ABCG1/PPP3R1	4.24567522657505
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	14/146	388/9376	2.31718683801723	SLC39A3/TNF/PSMD12/CSNK1E/NDUFC1/PSMA3/CSF1/NDUFC2/CASP7/PSMA1/SLC39A11/CSNK1A1/PPP3R1/NDUFB6	3.33267473318238
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	5/146	63/9376	5.09676016525332	HPGDS/LTC4S/TBXAS1/PTGES2/PTGS1	4.10324292012779
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	5/146	70/9376	4.58708414872798	ACSL4/TNF/ADIPOR1/NFKBIE/STK11	3.78852603691228
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	13/146	368/9376	2.26861226920786	TNF/PSMD12/HNRNPA2B1/RAB5A/NDUFC1/TP53/PSMA3/NDUFC2/PSMA1/NUP153/PPP3R1/NDUFB6/DERL1	3.12248128075632
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	5/146	73/9376	4.39857384124601	CDK9/XPO1/TNPO3/NUP153/BST2	3.66612987022267
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	8/146	174/9376	2.9526058888364	HSPH1/HSPA1A/STT3A/HSP90AA1/HSP90AB1/DNAJB11/SEC63/DERL1	3.269710636002
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	6/146	109/9376	3.53500062837753	AHR/LAT/HSP90AA1/HSP90AB1/NFKBIE/PPP3R1	3.34798076627341
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	15/146	480/9376	2.00684931506849	TNF/PSMD12/CSNK1E/PRKCA/RAB5A/NDUFC1/PSMA3/CSF1/NDUFC2/CASP7/PSMA1/CSNK1A1/PPP3R1/NDUFB6/DERL1	2.8480586345198
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	10/146	268/9376	2.39623798814148	SLC39A3/SLC18A2/PSMD12/NDUFC1/TP53/PSMA3/NDUFC2/PSMA1/SLC39A11/NDUFB6	2.91659785137961
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	10/146	275/9376	2.33524283935243	STIP1/TNF/PSMD12/HSPA1A/NDUFC1/PSMA3/NDUFC2/PSMA1/PPP3R1/NDUFB6	2.82646272827308
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	4/146	56/9376	4.58708414872798	TNF/HSPA1A/CASP7/HSPD1	3.38601468842482
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	7/146	157/9376	2.8632754558939	TNF/ADIPOR1/NDUFC1/NDUFC2/CASP7/SREBF1/NDUFB6	2.96105311329333
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	7/146	158/9376	2.84515345933761	CCNH/TFDP1/BUB3/CDC14A/TP53/SMC1A/YWHAG	2.94173737951567
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	6/146	122/9376	3.15832023355042	TNF/LAT/GRAP2/NFKBIE/PAK1/PPP3R1	3.0178125859493
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	3/146	34/9376	5.66639806607575	CSNK1E/BHLHE40/PER1	3.42817138915905
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	7/146	178/9376	2.52547329536709	CACYBP/CSNK1E/PRKCA/TP53/CSNK1A1/TLE4/PPP3R1	2.58421785905787
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	4/146	69/9376	3.72285090331547	MS4A2/TNF/LAT/PRKCA	2.85499114165929
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	3/146	41/9376	4.69896424991647	TP53/TYMP/DAPK2	2.98521844746143
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	3/146	42/9376	4.58708414872798	ACSL4/TP53/ATG7	2.93017478855852
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	4/146	78/9376	3.29329118370214	TOB1/ENO2/HSPD1/CNOT9	2.55783748390279
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	3/146	46/9376	4.1882072662299	PSMD12/PSMA3/PSMA1	2.72612557305734
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	6/146	158/9376	2.43870296514652	TNF/PRKCA/DDIT4/LAMTOR3/RPS6KA1/STK11	2.29373132580035
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	4/146	82/9376	3.13264283327765	TNF/HSPA1A/HSP90AA1/HSP90AB1	2.4394107609759
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	5/146	125/9376	2.56876712328767	MS4A2/NSMAF/TNF/PRKCA/TP53	2.22065126144171
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	7/146	217/9376	2.07158638974812	AHR/BCL6/PRKCA/HSP90AA1/HSP90AB1/RPS6KA1/ARRB1	2.00860362423013
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	6/146	173/9376	2.22725473117428	TPSB2/TPSAB1/TNF/PRKCA/TRIM25/XPO1	2.04905809232698
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	10/146	362/9376	1.77401044425944	KIT/MCL1/PRKCA/TP53/CSF1/HSP90AA1/HSP90AB1/DDIT4/STK11/YWHAG	1.88887641940061
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	3/146	56/9376	3.44031311154599	CSNK1E/CSNK1A1/ARRB1	2.30352444979037
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	5/146	133/9376	2.41425481511999	TNF/LAT/PRKCA/PAK1/PPP3R1	2.06589490991722
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	5/146	137/9376	2.34376562343766	TNF/LMNB1/MCL1/TP53/CASP7	1.992656968343
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	5/146	139/9376	2.31004237705726	FKBP4/HSPA1A/HSP90AA1/FKBP5/HSP90AB1	1.95698946739298
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	4/146	98/9376	2.62119094213028	LAT/PRKCA/PIP5K1A/PAK1	2.02899621993231
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	2/146	29/9376	4.42890883325461	CSNK1E/PAK1	2.32584105119777
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	2/146	31/9376	4.14317277949624	SRP9/SEC63	2.20455360991848
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	3/146	67/9376	2.87548558576978	PRKCA/RPS6KA1/PPP3R1	1.93758530687814
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	4/146	108/9376	2.37848807711821	XPO1/TNPO3/NUP153/ACIN1	1.81210389936914
Human Diseases	Immune disease	hsa05310	Asthma	2/146	32/9376	4.01369863013699	MS4A2/TNF	2.14768018649953
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	3/146	69/9376	2.7921381774866	SLC18A2/PRKCA/PPP3R1	1.87911083016831
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	2/146	33/9376	3.89207139892071	STX6/STX11	2.09307129468221
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	6/146	201/9376	1.91699039051319	ID2/BCL6/ETV6/CDK9/TP53/DUSP6	1.65280261913387
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	3/146	75/9376	2.56876712328767	MAT2A/ENO2/GPT2	1.71547938828343
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	2/146	37/9376	3.47130692336172	TNF/PRKCA	1.89425558224699
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	2/146	38/9376	3.37995674116799	PNP/NAMPT	1.84882217867635
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	4/146	122/9376	2.10554682236694	ADIPOR1/RAB14/SREBF1/STK11	1.54580078666407
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	5/146	169/9376	1.89997568290508	ATG7/VMP1/DDIT4/STK11/DAPK2	1.48482841975325
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	3/146	83/9376	2.32117511140452	TFDP1/PHF19/EED	1.52048687965481
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	3/146	85/9376	2.2665592264303	PNP/TYMP/DCTPP1	1.47524771737968
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	5/146	180/9376	1.78386605783866	TNF/SRSF6/TP53/SRSF2/BST2	1.33548755805897
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	2/146	44/9376	2.91905354919054	GTF2H2/CCNH	1.60467572277952
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/146	44/9376	2.91905354919054	TNF/HSPD1	1.60467572277952
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	5/146	181/9376	1.77401044425944	TNF/RAB5A/HSPD1/PPP3R1/ATP6V0A2	1.32242623734521
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	6/146	235/9376	1.63963858933256	ACSL4/NDUFC1/NDUFC2/COX14/RPS6KA1/NDUFB6	1.24891519368721
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/146	46/9376	2.7921381774866	ALAS1/BLVRA	1.5323952642125
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	3/146	90/9376	2.14063926940639	ADIPOR1/TP53/STK11	1.36746572535648
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/146	90/9376	2.14063926940639	LAT/NFKBIE/PPP3R1	1.36746572535648
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	6/146	238/9376	1.61897087602164	KIT/LAT/PRKCA/RAB5A/CSF1/PAK1	1.21645019459907
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	4/146	138/9376	1.86142545165773	NDUFC1/NDUFC2/NDUFB6/ATP6V0A2	1.28212237423071
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	4/146	138/9376	1.86142545165773	RPS6KA1/SMC1A/PPP3R1/YWHAG	1.28212237423071
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/146	138/9376	1.86142545165773	TNF/LAT/PIP5K1A/RPS6KA1	1.28212237423071
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	2/146	48/9376	2.67579908675799	IVD/HIBCH	1.46389360969033
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/146	93/9376	2.07158638974812	LAT/NFKBIE/PPP3R1	1.3061278914604
Genetic Information Processing	Transcription	hsa03040	Spliceosome	6/146	243/9376	1.58565871807881	HSPA1A/CTNNBL1/SRSF6/SRSF2/DHX15/ACIN1	1.16332814707091
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	3/146	94/9376	2.04954823666569	TNF/HSP90AA1/HSP90AB1	1.28619484213132
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	4/146	142/9376	1.80899093189273	UBE2M/UBE2S/UBE2A/PIAS1	1.2216705541417
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	4/146	142/9376	1.80899093189273	TNF/TP53/HSP90AA1/HSP90AB1	1.2216705541417
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/146	95/9376	2.02797404470079	TNF/CSF1/ATP6V0A2	1.2665075444828
Genetic Information Processing	Replication and repair	hsa03450	Non-homologous end-joining	1/146	13/9376	4.93993677555321	FEN1	1.78778229815361
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	4/146	144/9376	1.78386605783866	PSMD12/PRKCA/PSMA3/PSMA1	1.19216515287826
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/146	51/9376	2.51839914047811	PRKCA/ATP6V0A2	1.36743859258755
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	6/146	248/9376	1.55368979231109	TNF/RAB5A/HSP90AA1/CASP7/HSP90AB1/PAK1	1.11138813835273
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	3/146	98/9376	1.96589320659771	PRKCA/INPP1/PIP5K1A	1.20886048281879
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	4/146	149/9376	1.72400478072998	KIT/MS4A2/PRKCA/PIP5K1A	1.12038045356527
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	4/146	149/9376	1.72400478072998	PRKCA/NDUFC1/NDUFC2/NDUFB6	1.12038045356527
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	3/146	100/9376	1.92657534246575	KIT/TNF/CSF1	1.1715520394759
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	7/146	308/9376	1.45952677459527	PSMD12/NDUFC1/TP53/PSMA3/NDUFC2/PSMA1/NDUFB6	1.03131572327014
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	3/146	102/9376	1.88879935535858	CPA3/RAB27B/PRKCA	1.13509310764968
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	5/146	205/9376	1.56632141663882	TNF/PSMD12/TP53/NFKBIE/CD58	1.03108100239967
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	3/146	103/9376	1.87046149753957	TNF/PRKCA/RAB5A	1.11716999812736
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	3/146	105/9376	1.83483365949119	TNF/LAT/TRIM25	1.08191346424538
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	3/146	105/9376	1.83483365949119	MUL1/RAB5A/TP53	1.08191346424538
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	3/146	105/9376	1.83483365949119	TNF/PAK1/PPP3R1	1.08191346424538
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	4/146	156/9376	1.64664559185107	TNF/TP53/PIAS1/YWHAG	1.02429340288308
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	3/146	106/9376	1.81752390798656	TP53/HSP90AA1/HSP90AB1	1.06457127444515
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	4/146	157/9376	1.63615740336794	PTGER4/RAB5A/CASP7/RAB14	1.0109594122698
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	2/146	59/9376	2.17692129092176	TYMP/DCTPP1	1.14050342313446
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/146	59/9376	2.17692129092176	PTGS1/ABHD5	1.14050342313446
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	5/146	212/9376	1.51460325665547	KIT/LAT/P2RY1/PRKCA/CSF1	0.953145355749978
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	2/146	60/9376	2.14063926940639	PRKCA/PPP3R1	1.11473187596605
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	5/146	214/9376	1.50044808603252	TNF/PRKCA/BST2/PAK1/PPP3R1	0.931390901597526
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	3/146	109/9376	1.76750031418876	TNF/SREBF1/RPS6KA1	1.01363931087362
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	3/146	110/9376	1.75143212951432	ID2/TNF/TFDP1	0.997013802794284
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	3/146	110/9376	1.75143212951432	HSP90AA1/HSP90AB1/RPS6KA1	0.997013802794284
Metabolism	Lipid metabolism	hsa00061	Fatty acid biosynthesis	1/146	18/9376	3.56773211567732	ACSL4	1.3713732085272
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	2/146	63/9376	2.03870406610133	GTF2H2/CCNH	1.04034772196011
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	3/146	115/9376	1.67528290649196	SLC18A2/PRKCA/PTGS1	0.916361744156536
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/146	65/9376	1.97597471022129	PRKCA/ARRB1	0.993020684308376
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	1/146	20/9376	3.21095890410959	TGDS	1.24483496156466
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	3/146	116/9376	1.66084081247048	ENO2/HIBCH/GPT2	0.900702925461373
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	5/146	224/9376	1.4334637964775	TNF/BUB3/TP53/XPO1/PPP3R1	0.825809832408569
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	5/146	227/9376	1.41451934101744	TNF/PTGER4/PRKCA/TP53/PPP3R1	0.795118996425958
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	5/146	227/9376	1.41451934101744	AHR/NDUFC1/NDUFC2/NDUFB6/AKR1A1	0.795118996425958
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	2/146	67/9376	1.91699039051319	ENO2/AKR1A1	0.947353112542076
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	3/146	119/9376	1.61897087602164	TNF/CSF1/CASP7	0.854613559933956
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	2/146	68/9376	1.88879935535858	KIT/DUSP6	0.925105399043436
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	3/146	120/9376	1.60547945205479	TP53/NFKBIE/RPS6KA1	0.839536485361319
Organismal Systems	Endocrine system	hsa04924	Renin secretion	2/146	69/9376	1.86142545165773	PTGER4/PPP3R1	0.903230518677336
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/146	22/9376	2.91905354919054	HDC	1.13334195631083
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	1/146	23/9376	2.7921381774866	GPT2	1.08223396061636
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	1/146	23/9376	2.7921381774866	CPA3	1.08223396061636
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/146	71/9376	1.80899093189273	PAK1/ATP6V0A2	0.860549496367314
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	2/146	71/9376	1.80899093189273	KIT/TP53	0.860549496367314
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	2/146	72/9376	1.78386605783866	TNF/TRIM25	0.83971995226943
Organismal Systems	Immune system	hsa04611	Platelet activation	3/146	126/9376	1.52902804957599	TBXAS1/P2RY1/PTGS1	0.751890021292498
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	2/146	73/9376	1.7594295364984	PRKCA/TP53	0.819216364904817
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	4/146	184/9376	1.3960690887433	ROBO1/PRKCA/PAK1/PPP3R1	0.682395365119594
Human Diseases	Cancer: specific types	hsa05214	Glioma	2/146	76/9376	1.68997837058399	PRKCA/TP53	0.759559874642654
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	4/146	187/9376	1.3736722584426	TNF/HSP90AA1/HSP90AB1/NAMPT	0.649140566164851
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	2/146	77/9376	1.66803059953745	ARHGEF6/TP53	0.740260899084018
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	3/146	133/9376	1.44855288907199	BCL6/CSNK1E/STK11	0.655230670212622
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	3/146	133/9376	1.44855288907199	SLC18A2/PRKCA/ARRB1	0.655230670212622
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	2/146	78/9376	1.64664559185107	INPP1/PIP5K1A	0.721240436187018
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	2/146	78/9376	1.64664559185107	TNF/CASP7	0.721240436187018
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	2/146	79/9376	1.62580197676435	SLC18A2/ATP6V0A2	0.702490210261597
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	5/146	250/9376	1.28438356164384	GNPTG/LAMTOR3/ATP6V0A2/GALC/OSBPL3	0.573185871304216
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	5/146	250/9376	1.28438356164384	RAB5A/HSPA1A/ARFGEF1/PIP5K1A/ARRB1	0.573185871304216
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	1/146	28/9376	2.29354207436399	ATP6V0A2	0.862107530646649
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	2/146	83/9376	1.54745007426968	ACSL4/FAR1	0.630038098665209
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/146	30/9376	2.14063926940639	TNF	0.786968363366247
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/146	142/9376	1.35674319891954	TNF/CSF1/PPP3R1	0.53872379074839
Metabolism	Carbohydrate metabolism	hsa00053	Ascorbate and aldarate metabolism	1/146	31/9376	2.07158638974812	AKR1A1	0.751587586679645
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	1/146	31/9376	2.07158638974812	HIBCH	0.751587586679645
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/146	31/9376	2.07158638974812	HYI	0.751587586679645
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	2/146	86/9376	1.49346925772539	PRKCA/PAK1	0.578179496074792
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	3/146	144/9376	1.337899543379	TNF/ADIPOR1/SREBF1	0.51390420182325
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	4/146	204/9376	1.25919957023905	TNF/PRKCA/TP53/PAK1	0.47073723643142
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/146	32/9376	2.00684931506849	HIBCH	0.71752042594416
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/146	32/9376	2.00684931506849	ATG7	0.71752042594416
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/146	32/9376	2.00684931506849	CASP7	0.71752042594416
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	4/146	205/9376	1.25305713331106	PRKCA/NDUFC1/NDUFC2/NDUFB6	0.460732006617998
Metabolism	Global and overview maps	hsa01210	2-Oxocarboxylic acid metabolism	1/146	33/9376	1.94603569946036	GPT2	0.684671950707731
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	3/146	148/9376	1.30174009626064	KIT/TP53/CSNK1A1	0.465340985121866
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	2/146	91/9376	1.41141050730092	NFKBIE/PPP3R1	0.495982481296789
Human Diseases	Substance dependence	hsa05032	Morphine addiction	2/146	91/9376	1.41141050730092	PRKCA/ARRB1	0.495982481296789
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/146	93/9376	1.38105759316541	CKS2/TP53	0.464460873568118
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	3/146	154/9376	1.25102294965309	ALAS1/MAT2A/AKR1A1	0.395023056933619
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	1/146	36/9376	1.78386605783866	AKR1A1	0.592626254043602
Genetic Information Processing	Replication and repair	hsa03030	DNA replication	1/146	36/9376	1.78386605783866	FEN1	0.592626254043602
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	1/146	37/9376	1.73565346168086	GPT2	0.563878028752773
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	1/146	37/9376	1.73565346168086	TGDS	0.563878028752773
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/146	37/9376	1.73565346168086	TP53	0.563878028752773
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	3/146	157/9376	1.22711805252596	ID2/CSNK1E/YWHAG	0.360928178595296
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/146	97/9376	1.32410676458127	PRKCA/PER1	0.403538142727002
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/146	38/9376	1.68997837058399	PRKCA	0.535996008783178
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	2/146	99/9376	1.29735713297357	PTGER4/PRKCA	0.374070444182483
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/146	99/9376	1.29735713297357	PRKCA/PIP5K1A	0.374070444182483
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/146	39/9376	1.64664559185107	MAT2A	0.508927783996304
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/146	39/9376	1.64664559185107	TNF	0.508927783996304
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/146	100/9376	1.28438356164384	TNF/CSF1	0.359571560312236
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/146	163/9376	1.18194806286243	TNF/PRKCA/TP53	0.294714781371547
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	2/146	101/9376	1.27166689271667	KIT/PRKCA	0.345224539295724
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/146	101/9376	1.27166689271667	TNF/PRKCA	0.345224539295724
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/146	41/9376	1.56632141663882	ALAS1	0.457045006634191
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	2/146	103/9376	1.24697433169304	FIP1L1/ACIN1	0.316972450194424
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	3/146	168/9376	1.146771037182	TNF/HSP90AA1/HSP90AB1	0.241420177218655
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/146	232/9376	1.10722720831365	ARHGEF6/PIP5K1A/PAK1/SPATA13	0.207989829308297
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/146	43/9376	1.49346925772539	ACSL4	0.407891741667787
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/146	170/9376	1.13327961321515	PRKCA/TP53/CSNK1A1	0.220553480014829
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/146	44/9376	1.45952677459527	STT3A	0.384247463793409
Genetic Information Processing	Replication and repair	hsa03410	Base excision repair	1/146	44/9376	1.45952677459527	FEN1	0.384247463793409
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/146	44/9376	1.45952677459527	RAB5A	0.384247463793409
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/146	45/9376	1.42709284627093	ABCG1	0.361181647683393
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/146	45/9376	1.42709284627093	TNF	0.361181647683393
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/146	110/9376	1.16762141967621	ENO2/PRKCA	0.222403145270319
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/146	47/9376	1.36636549111046	AKR1A1	0.316670171770292
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/146	47/9376	1.36636549111046	TNF	0.316670171770292
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/146	112/9376	1.146771037182	TNF/HSPA1A	0.19652206411552
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/146	49/9376	1.31059547106514	SLC18A2	0.274146929463065
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/146	115/9376	1.11685527099464	PRKCA/ARRB1	0.158573094199605
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	2/146	116/9376	1.10722720831365	PRKCA/PPP3R1	0.146146936440123
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/146	50/9376	1.28438356164384	TNF	0.253572995605149
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/146	53/9376	1.21168260532437	PRKCA	0.194359816475604
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/146	122/9376	1.05277341118347	PRKCA/TP53	0.0737889873788457
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/146	54/9376	1.18924403855911	MAT2A	0.175398451027684
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/146	55/9376	1.16762141967621	GALC	0.156798109072453
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/146	56/9376	1.146771037182	STT3A	0.138543972521474
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/146	57/9376	1.126652247056	ACSL4	0.120622100503074
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	5/146	333/9376	0.964251923156033	TNF/PTGER4/TP53/CSNK1A1/ATP6V0A2	-0.0835371683088758
NA	NA	hsa04082	Neuroactive ligand signaling	3/146	199/9376	0.968128312796861	SLC18A2/P2RY1/PRKCA	-0.0571534488455235
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/146	130/9376	0.987987355110643	PRKCA/ARRB1	-0.0173458100448054
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/146	59/9376	1.08846064546088	HPGDS	0.0857233782233635
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/146	59/9376	1.08846064546088	TP53	0.0857233782233635
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/146	200/9376	0.963287671232877	TNF/CASP7/PAK1	-0.0660026609574588
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/146	60/9376	1.0703196347032	PRKCA	0.0687224615287319
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/146	203/9376	0.949051892840273	PRKCA/PIP5K1A/PAK1	-0.0922957262234353
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/146	205/9376	0.939792849983294	GTF2H2/TP53/YWHAG	-0.10961698916367
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/146	62/9376	1.03579319487406	HSPA1A	0.0355622645560794
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/146	62/9376	1.03579319487406	TLE4	0.0355622645560794
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/146	63/9376	1.01935203305066	TP53	0.0193826559042181
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/146	136/9376	0.944399677679291	HSPA1A/TP53	-0.0821432711199096
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/146	65/9376	0.987987355110643	AKR1A1	-0.0122224528191702
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/146	66/9376	0.973017849730178	TNF	-0.0276652691351577
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/146	70/9376	0.917416829745597	HPGDS	-0.0872208394750128
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/146	70/9376	0.917416829745597	PAK1	-0.0872208394750128
Genetic Information Processing	Translation	hsa03010	Ribosome	3/146	222/9376	0.867826730840429	MRPL19/MRPL3/MRPL52	-0.25065471630335
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	2/146	150/9376	0.856255707762557	TP53/CSNK1A1	-0.223198221041029
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/146	73/9376	0.879714768249202	HPGDS	-0.129754803534467
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/146	73/9376	0.879714768249202	TP53	-0.129754803534467
NA	NA	hsa04517	IgSF CAM signaling	4/146	299/9376	0.859119439226646	ROBO1/PRKCA/CD226/PAK1	-0.311369962011438
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/146	75/9376	0.856255707762557	TP53	-0.157187365069165
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/146	75/9376	0.856255707762557	TP53	-0.157187365069165
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/146	75/9376	0.856255707762557	PRKCA	-0.157187365069165
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/146	154/9376	0.834015299768724	PRKCA/PPP3R1	-0.261202347355823
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/146	76/9376	0.844989185291997	ACSL4	-0.170643023038841
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/146	76/9376	0.844989185291997	PRKCA	-0.170643023038841
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/146	155/9376	0.828634555899249	RAB5A/ATP6V0A2	-0.270558575971241
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/146	77/9376	0.834015299768724	TP53	-0.183931669466149
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	2/146	157/9376	0.818078701683972	TP53/PPP3R1	-0.289103055079213
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/146	78/9376	0.823322795925536	TNF	-0.197058087670869
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/146	79/9376	0.812900988382174	HPGDS	-0.210026859759563
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/146	160/9376	0.802739726027397	CD226/CD58	-0.316511581423403
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/146	80/9376	0.802739726027397	PRKCA	-0.222842377621714
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/146	82/9376	0.783160708319412	TYMP	-0.248030328039066
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/146	83/9376	0.773725037134841	CASP7	-0.26041068232439
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/146	168/9376	0.764514024787997	MCL1/PIAS1	-0.387345262115264
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/146	86/9376	0.746734628862695	P2RY1	-0.296741574809206
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/146	86/9376	0.746734628862695	PRKCA	-0.296741574809206
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	4/146	323/9376	0.79528393909835	MCL1/PRKCA/TP53/DDIT4	-0.47088855275825
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/146	87/9376	0.738151472209101	TP53	-0.308593303021117
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	2/146	170/9376	0.755519742143433	STK11/RAB8B	-0.404570289217045
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/146	89/9376	0.721563798676312	PRKCA	-0.331928234697255
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/146	89/9376	0.721563798676312	PRKCA	-0.331928234697255
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/146	93/9376	0.690528796582707	FER	-0.377206144324165
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/146	93/9376	0.690528796582707	PRKCA	-0.377206144324165
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/146	93/9376	0.690528796582707	PRKCA	-0.377206144324165
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	2/146	183/9376	0.701848940788981	XPO1/GTPBP4	-0.512264767391109
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/146	98/9376	0.655297735532569	PRKCA	-0.431410991408267
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/146	99/9376	0.648678566486786	TP53	-0.441956657877768
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/146	99/9376	0.648678566486786	TNF	-0.441956657877768
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/146	103/9376	0.623487165846522	CPA3	-0.483225097738511
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/146	103/9376	0.623487165846522	TNF	-0.483225097738511
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/146	104/9376	0.617492096944152	MBOAT7	-0.49332325272857
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	2/146	193/9376	0.665483710696288	PAK1/ARRB1	-0.590561116006859
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/146	105/9376	0.611611219830398	TNF	-0.503337456330442
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/146	195/9376	0.658658236740429	PRKCA/ATG7	-0.605791192833252
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/146	196/9376	0.655297735532569	TP53/PPP3R1	-0.613355193711372
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/146	107/9376	0.600179234413007	PPP3R1	-0.523120825599077
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/146	109/9376	0.589166771396255	TNF	-0.542588326059579
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/146	115/9376	0.55842763549732	PRKCA	-0.599215555757326
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/146	116/9376	0.553613604156826	PRKCA	-0.608409052581128
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/146	122/9376	0.526386705591736	PRKCA	-0.662216912263768
NA	NA	hsa04081	Hormone signaling	2/146	219/9376	0.586476512166135	ADIPOR1/STK11	-0.778765759044574
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/146	128/9376	0.501712328767123	PNP	-0.713875425019264
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/146	134/9376	0.479247597628297	PRKCA	-0.763592958385124
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	2/146	233/9376	0.551237580104651	LMNB1/ENO2	-0.87239124286196
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/146	138/9376	0.465356362914433	SREBF1	-0.795749148145494
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	2/146	238/9376	0.53965695867388	TNF/PRKCA	-0.904702311363528
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/146	143/9376	0.449085161413929	TNF	-0.834915044078665
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/146	144/9376	0.445966514459665	ID2	-0.84261770028677
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/146	253/9376	0.507661486815745	TNF/TP53	-0.998427302552836
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/146	254/9376	0.505662819544817	PRKCA/PPP3R1	-1.00451474519161
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/146	154/9376	0.417007649884362	PRKCA	-0.917427751645266
NA	NA	hsa04518	Integrin signaling	1/146	154/9376	0.417007649884362	ARHGEF6	-0.917427751645266
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/146	155/9376	0.414317277949624	AHR	-0.924699166045081
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/146	166/9376	0.38686251856742	PPP3R1	-1.00240519814489
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/146	298/9376	0.431001195182495	TNF/CSF1	-1.25541008343054
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/146	191/9376	0.336226063257549	SLC18A2	-1.16562409044715
NA	NA	hsa04519	Cadherin signaling	3/146	404/9376	0.476875084768751	CSNK1A1/YWHAG/TAOK3	-1.3518007113444
NA	NA	hsa04382	Cornified envelope formation	1/146	217/9376	0.29594091282116	ABHD5	-1.31970287016428
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/146	226/9376	0.284155655230937	PAK1	-1.37000920911215
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	2/146	370/9376	0.347130692336172	PTGER4/P2RY1	-1.61147049612291
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/146	449/9376	0.143027122677487	ARRB1	-2.34044637920883