ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0043021 ribonucleoprotein complex binding 34/1313 177/18639 0.192090395480226 2.72686434223605 7.15797436946044e-08 7.37271360054425e-05 GO:0043022 ribosome binding 24/1313 112/18639 0.214285714285714 3.04194320530954 7.55351421077946e-07 0.000318250600203834 GO:0015631 tubulin binding 54/1313 385/18639 0.14025974025974 1.99109009802079 9.26943495739323e-07 0.000318250600203834 GO:0140662 ATP-dependent protein folding chaperone 13/1313 40/18639 0.325 4.61361386138614 1.97727949908558e-06 0.000489324258013754 GO:0019787 ubiquitin-like protein transferase activity 62/1313 479/18639 0.129436325678497 1.8374437732837 2.37536047579492e-06 0.000489324258013754 GO:0016755 aminoacyltransferase activity 63/1313 496/18639 0.127016129032258 1.80308730314719 3.70202024082618e-06 0.00063551347467516 GO:0003697 single-stranded DNA binding 23/1313 121/18639 0.190082644628099 2.69836284327733 1.07965033704047e-05 0.00123725410834344 GO:0051082 unfolded protein binding 23/1313 121/18639 0.190082644628099 2.69836284327733 1.07965033704047e-05 0.00123725410834344 GO:0004842 ubiquitin-protein transferase activity 57/1313 449/18639 0.126948775055679 1.8021311639473 1.08109582282436e-05 0.00123725410834344 GO:0044389 ubiquitin-like protein ligase binding 44/1313 322/18639 0.136645962732919 1.93978987005246 1.79357992301885e-05 0.00184738732070941 GO:0008017 microtubule binding 39/1313 276/18639 0.141304347826087 2.00591907016789 2.46386022964912e-05 0.00230706912412599 GO:0051539 4 iron, 4 sulfur cluster binding 12/1313 45/18639 0.266666666666667 3.78552932216299 4.61036329958738e-05 0.0039572284988125 GO:0031625 ubiquitin protein ligase binding 40/1313 302/18639 0.132450331125828 1.88022979577632 8.54133807165311e-05 0.00676736785677131 GO:0043175 RNA polymerase core enzyme binding 11/1313 42/18639 0.261904761904762 3.71793058426722 0.000113739389433131 0.00836796936543746 GO:0061659 ubiquitin-like protein ligase activity 46/1313 372/18639 0.123655913978495 1.75538658084171 0.000139158578530729 0.00955555572577674 GO:0016853 isomerase activity 27/1313 180/18639 0.15 2.12936024371668 0.000154806522381711 0.00974216022073946 GO:0061630 ubiquitin protein ligase activity 44/1313 353/18639 0.124645892351275 1.76944005143596 0.000160792935682108 0.00974216022073946 GO:0070063 RNA polymerase binding 13/1313 59/18639 0.220338983050847 3.12787380432959 0.00018943943594791 0.0108401455014637 GO:0051540 metal cluster binding 15/1313 77/18639 0.194805194805195 2.76540291391777 0.000268455930837452 0.0145531373032934 GO:0016887 ATP hydrolysis activity 49/1313 417/18639 0.117505995203837 1.66808396390275 0.000293319761430578 0.0151059677136748 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 11/1313 48/18639 0.229166666666667 3.25318926123382 0.000406376055678347 0.0191509703959506 GO:0051010 microtubule plus-end binding 7/1313 21/18639 0.333333333333333 4.73191165270373 0.000409049853117392 0.0191509703959506 GO:0003688 DNA replication origin binding 6/1313 16/18639 0.375 5.3234006092917 0.000522788851279348 0.0230061167115545 GO:0019207 kinase regulator activity 36/1313 287/18639 0.125435540069686 1.7806496811568 0.000541248772426178 0.0230061167115545 GO:0003684 damaged DNA binding 14/1313 74/18639 0.189189189189189 2.68567958666969 0.000580214098702375 0.0230061167115545 GO:0016757 glycosyltransferase activity 34/1313 267/18639 0.127340823970037 1.80769658642614 0.000580736926699434 0.0230061167115545 GO:0044183 protein folding chaperone 14/1313 75/18639 0.186666666666667 2.64987052551409 0.00066791214470039 0.0243035449029161 GO:0016758 hexosyltransferase activity 27/1313 197/18639 0.137055837563452 1.9456083445127 0.000672273865813919 0.0243035449029161 GO:0000993 RNA polymerase II complex binding 9/1313 36/18639 0.25 3.5489337395278 0.000687692765528886 0.0243035449029161 GO:0051536 iron-sulfur cluster binding 14/1313 76/18639 0.184210526315789 2.61500380807311 0.00076657518946938 0.0243035449029161 GO:0140097 catalytic activity, acting on DNA 40/1313 336/18639 0.119047619047619 1.68996844739419 0.000786858150141855 0.0243035449029161 GO:0030145 manganese ion binding 13/1313 68/18639 0.191176470588235 2.71389050669773 0.000813175277193814 0.0243035449029161 GO:0031072 heat shock protein binding 20/1313 131/18639 0.152671755725191 2.1672877798643 0.000839873860611377 0.0243035449029161 GO:0001098 basal transcription machinery binding 12/1313 60/18639 0.2 2.83914699162224 0.000840709219055858 0.0243035449029161 GO:0001099 basal RNA polymerase II transcription machinery binding 12/1313 60/18639 0.2 2.83914699162224 0.000840709219055858 0.0243035449029161 GO:0016829 lyase activity 27/1313 200/18639 0.135 1.91642421934501 0.000849638126341185 0.0243035449029161 GO:0005049 nuclear export signal receptor activity 5/1313 12/18639 0.416666666666667 5.91488956587966 0.000896635637194962 0.0243035449029161 GO:0043047 single-stranded telomeric DNA binding 5/1313 12/18639 0.416666666666667 5.91488956587966 0.000896635637194962 0.0243035449029161 GO:0140098 catalytic activity, acting on RNA 44/1313 387/18639 0.113695090439276 1.61398536991445 0.00114968573338328 0.0303634950098662 GO:0004386 helicase activity 22/1313 155/18639 0.141935483870968 2.01487851018352 0.0012833053075206 0.0330451116686556 GO:0016779 nucleotidyltransferase activity 20/1313 136/18639 0.147058823529412 2.08760808207518 0.00134869865289498 0.0336681399904071 GO:0140852 histone ubiquitin ligase activity 5/1313 13/18639 0.384615384615385 5.459898060812 0.00137287561125932 0.0336681399904071 GO:0043130 ubiquitin binding 16/1313 100/18639 0.16 2.27131759329779 0.00162510409515848 0.0389269120468193 GO:0008094 ATP-dependent activity, acting on DNA 27/1313 210/18639 0.128571428571429 1.82516592318573 0.00176682254569571 0.0413597095924224 GO:0098847 sequence-specific single stranded DNA binding 5/1313 14/18639 0.357142857142857 5.06990534218257 0.00201247026581033 0.0460632083063253 GO:0019887 protein kinase regulator activity 31/1313 255/18639 0.12156862745098 1.72575601451548 0.00209363137804935 0.0468791373780616 GO:0140104 molecular carrier activity 30/1313 249/18639 0.120481927710843 1.71032951302545 0.00280212301897061 0.0610493484276539 GO:0050700 CARD domain binding 5/1313 15/18639 0.333333333333333 4.73191165270373 0.0028450181791528 0.0610493484276539 GO:0106310 protein serine kinase activity 40/1313 361/18639 0.110803324099723 1.57293462139736 0.00299057382084661 0.0628630823565716 GO:0016860 intramolecular oxidoreductase activity 10/1313 53/18639 0.188679245283019 2.67844055813419 0.00349669630302544 0.072031943842324 GO:0098505 G-rich strand telomeric DNA binding 4/1313 10/18639 0.4 5.67829398324448 0.00364749960535245 0.0723955909457662 GO:0004715 non-membrane spanning protein tyrosine kinase activity 9/1313 45/18639 0.2 2.83914699162224 0.00365492303803868 0.0723955909457662 GO:0140463 chromatin-protein adaptor activity 10/1313 54/18639 0.185185185185185 2.62883980705763 0.00402615954404317 0.0781812806105436 GO:0070566 adenylyltransferase activity 7/1313 30/18639 0.233333333333333 3.31233815689261 0.0040988244203586 0.0781812806105436 GO:0032182 ubiquitin-like protein binding 17/1313 120/18639 0.141666666666667 2.01106245239909 0.00442295980279625 0.0828299744887298 GO:0051020 GTPase binding 35/1313 315/18639 0.111111111111111 1.57730388423458 0.00502434617891959 0.0924120815051282 GO:0003735 structural constituent of ribosome 22/1313 175/18639 0.125714285714286 1.78460668044826 0.00585252476541856 0.102858360655786 GO:0003725 double-stranded RNA binding 12/1313 75/18639 0.16 2.27131759329779 0.00593470877533243 0.102858360655786 GO:0008378 galactosyltransferase activity 7/1313 32/18639 0.21875 3.10531702208682 0.00599174916441471 0.102858360655786 GO:0140142 nucleocytoplasmic carrier activity 7/1313 32/18639 0.21875 3.10531702208682 0.00599174916441471 0.102858360655786 GO:0051087 protein-folding chaperone binding 18/1313 134/18639 0.134328358208955 1.90688977049255 0.00610440062677463 0.103074305665211 GO:0000287 magnesium ion binding 27/1313 230/18639 0.117391304347826 1.66645584290871 0.00626245619035522 0.104037578646224 GO:0008194 UDP-glycosyltransferase activity 19/1313 145/18639 0.131034482758621 1.86013078761457 0.00644958829652286 0.105445649927279 GO:0017025 TBP-class protein binding 6/1313 25/18639 0.24 3.40697638994669 0.00669190191392215 0.107697796427185 GO:0140223 general transcription initiation factor activity 11/1313 68/18639 0.161764705882353 2.29636889028269 0.0075946364267442 0.116231031629044 GO:0004300 enoyl-CoA hydratase activity 4/1313 12/18639 0.333333333333333 4.73191165270373 0.0076735050007524 0.116231031629044 GO:0035251 UDP-glucosyltransferase activity 4/1313 12/18639 0.333333333333333 4.73191165270373 0.0076735050007524 0.116231031629044 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/1313 12/18639 0.333333333333333 4.73191165270373 0.0076735050007524 0.116231031629044 GO:0002039 p53 binding 11/1313 69/18639 0.159420289855072 2.26308818172787 0.0084752513229612 0.126240656829129 GO:0003756 protein disulfide isomerase activity 5/1313 19/18639 0.263157894736842 3.73571972581874 0.00870202585909531 0.126240656829129 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 5/1313 19/18639 0.263157894736842 3.73571972581874 0.00870202585909531 0.126240656829129 GO:0009982 pseudouridine synthase activity 4/1313 13/18639 0.307692307692308 4.3679184486496 0.010473784729416 0.147780798236965 GO:0140666 annealing activity 4/1313 13/18639 0.307692307692308 4.3679184486496 0.010473784729416 0.147780798236965 GO:0030742 GTP-dependent protein binding 5/1313 20/18639 0.25 3.5489337395278 0.0109418523710599 0.149664036264951 GO:0043024 ribosomal small subunit binding 5/1313 20/18639 0.25 3.5489337395278 0.0109418523710599 0.149664036264951 GO:0016251 RNA polymerase II general transcription initiation factor activity 9/1313 53/18639 0.169811320754717 2.41059650232077 0.0110431716078993 0.149664036264951 GO:0097718 disordered domain specific binding 6/1313 28/18639 0.214285714285714 3.04194320530954 0.0118849114425456 0.157714484752807 GO:0140297 DNA-binding transcription factor binding 48/1313 488/18639 0.0983606557377049 1.39630179915848 0.011943427000698 0.157714484752807 GO:0050661 NADP binding 9/1313 54/18639 0.166666666666667 2.36595582635187 0.0124465740206705 0.162278116978363 GO:0043539 protein serine/threonine kinase activator activity 11/1313 73/18639 0.150684931506849 2.13908334985237 0.0128105623052876 0.164935989680578 GO:0035173 histone kinase activity 37/1313 360/18639 0.102777777777778 1.45900609291698 0.013441718799189 0.17092556003907 GO:0035250 UDP-galactosyltransferase activity 6/1313 29/18639 0.206896551724138 2.93704861202301 0.0141134023619062 0.175210248324307 GO:0003678 DNA helicase activity 11/1313 74/18639 0.148648648648649 2.11017681809761 0.0141188840882694 0.175210248324307 GO:0140857 histone H3T45 kinase activity 27/1313 246/18639 0.109756097560976 1.5580684710122 0.0146334525247541 0.179434001196389 GO:0042162 telomeric DNA binding 7/1313 38/18639 0.184210526315789 2.61500380807311 0.0155608396216805 0.188560762474482 GO:0031267 small GTPase binding 30/1313 283/18639 0.106007067137809 1.50484822877504 0.0164812783393244 0.197392054529117 GO:0141003 histone H2AX kinase activity 36/1313 354/18639 0.101694915254237 1.44363406353673 0.0169555079386275 0.198720491194672 GO:0016407 acetyltransferase activity 13/1313 96/18639 0.135416666666667 1.92233910891089 0.0169780613836225 0.198720491194672 GO:0003689 DNA clamp loader activity 19/1313 160/18639 0.11875 1.6857435262757 0.0175299790915813 0.20218723532113 GO:0000217 DNA secondary structure binding 7/1313 39/18639 0.179487179487179 2.54795242837893 0.0178444030267569 0.20218723532113 GO:0055105 ubiquitin-protein transferase inhibitor activity 4/1313 15/18639 0.266666666666667 3.78552932216299 0.0178631440914784 0.20218723532113 GO:0140996 histone H3 kinase activity 36/1313 357/18639 0.100840336134454 1.43150268485155 0.0190593924752442 0.209325362347811 GO:0140030 modification-dependent protein binding 20/1313 173/18639 0.115606936416185 1.64112542868338 0.0196972358786256 0.209325362347811 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 7/1313 40/18639 0.175 2.48425361766946 0.0203536664278131 0.209325362347811 GO:0015616 DNA translocase activity 18/1313 152/18639 0.118421052631579 1.68107387661843 0.0209066987665436 0.209325362347811 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 26/1313 243/18639 0.106995884773663 1.51888522185552 0.021885010248507 0.209325362347811 GO:0008186 ATP-dependent activity, acting on RNA 11/1313 79/18639 0.139240506329114 1.97662132328131 0.02221963702274 0.209325362347811 GO:0034450 ubiquitin-ubiquitin ligase activity 4/1313 16/18639 0.25 3.5489337395278 0.0225173331337879 0.209325362347811 GO:0016877 ligase activity, forming carbon-sulfur bonds 7/1313 41/18639 0.170731707317073 2.42366206601898 0.0230984497965878 0.209325362347811 GO:0061650 ubiquitin-like protein conjugating enzyme activity 7/1313 41/18639 0.170731707317073 2.42366206601898 0.0230984497965878 0.209325362347811 GO:0003713 transcription coactivator activity 27/1313 256/18639 0.10546875 1.49720642136329 0.0233393705885108 0.209325362347811 GO:0004676 3-phosphoinositide-dependent protein kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0004711 ribosomal protein S6 kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0035175 histone H3S10 kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0035979 histone H2AXS139 kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0044022 histone H3S28 kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0044023 histone H4S1 kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0044024 histone H2AS1 kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0044025 histone H2BS14 kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0072354 histone H3T3 kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0072371 histone H2AS121 kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0072518 Rho-dependent protein serine/threonine kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0140823 histone H2BS36 kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0140855 histone H3S57 kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0140995 histone H2A kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0140997 histone H4 kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0140998 histone H2B kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:1990244 histone H2AT120 kinase activity 26/1313 245/18639 0.106122448979592 1.50648615881996 0.023980963841788 0.209325362347811 GO:0004677 DNA-dependent protein kinase activity 26/1313 246/18639 0.105691056910569 1.50036223134509 0.0250856697247102 0.217128065684466 GO:0004520 DNA endonuclease activity 7/1313 42/18639 0.166666666666667 2.36595582635187 0.0260879794764718 0.21787240589059 GO:0048487 beta-tubulin binding 7/1313 42/18639 0.166666666666667 2.36595582635187 0.0260879794764718 0.21787240589059 GO:0016836 hydro-lyase activity 9/1313 61/18639 0.147540983606557 2.09445269873772 0.0262223744775035 0.21787240589059 GO:0035402 histone H3T11 kinase activity 26/1313 247/18639 0.105263157894737 1.49428789032749 0.0262292993499351 0.21787240589059 GO:0035403 histone H3T6 kinase activity 26/1313 247/18639 0.105263157894737 1.49428789032749 0.0262292993499351 0.21787240589059 GO:0004679 AMP-activated protein kinase activity 26/1313 248/18639 0.104838709677419 1.48826253593101 0.0274126773635467 0.219550334061412 GO:0008429 phosphatidylethanolamine binding 4/1313 17/18639 0.235294117647059 3.34017293132028 0.0278429316090264 0.219550334061412 GO:0000030 mannosyltransferase activity 5/1313 25/18639 0.2 2.83914699162224 0.0280214583145284 0.219550334061412 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 5/1313 25/18639 0.2 2.83914699162224 0.0280214583145284 0.219550334061412 GO:0005522 profilin binding 3/1313 10/18639 0.3 4.25872048743336 0.0287760146585345 0.219550334061412 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 3/1313 10/18639 0.3 4.25872048743336 0.0287760146585345 0.219550334061412 GO:0016783 sulfurtransferase activity 3/1313 10/18639 0.3 4.25872048743336 0.0287760146585345 0.219550334061412 GO:0031996 thioesterase binding 3/1313 10/18639 0.3 4.25872048743336 0.0287760146585345 0.219550334061412 GO:0043422 protein kinase B binding 3/1313 10/18639 0.3 4.25872048743336 0.0287760146585345 0.219550334061412 GO:0051880 G-quadruplex DNA binding 3/1313 10/18639 0.3 4.25872048743336 0.0287760146585345 0.219550334061412 GO:1905394 retromer complex binding 3/1313 10/18639 0.3 4.25872048743336 0.0287760146585345 0.219550334061412 GO:0004712 protein serine/threonine/tyrosine kinase activity 7/1313 43/18639 0.162790697674419 2.31093359783206 0.029330829612373 0.220516456209811 GO:0008375 acetylglucosaminyltransferase activity 7/1313 43/18639 0.162790697674419 2.31093359783206 0.029330829612373 0.220516456209811 GO:0016741 transferase activity, transferring one-carbon groups 23/1313 215/18639 0.106976744186047 1.51861350714678 0.0297555207549577 0.222088307084104 GO:0008168 methyltransferase activity 22/1313 204/18639 0.107843137254902 1.5309125935218 0.030495158758463 0.225971320296524 GO:0034212 protein N-acetyltransferase activity 8/1313 53/18639 0.150943396226415 2.14275244650735 0.0310306330973752 0.226677674399266 GO:0140296 general transcription initiation factor binding 8/1313 53/18639 0.150943396226415 2.14275244650735 0.0310306330973752 0.226677674399266 GO:0004674 protein serine/threonine kinase activity 41/1313 433/18639 0.0946882217090069 1.34416889903593 0.0327503708831308 0.237555507110033 GO:0004860 protein kinase inhibitor activity 11/1313 84/18639 0.130952380952381 1.85896529213361 0.0332908184299376 0.239629132736823 GO:0000175 3'-5'-RNA exonuclease activity 6/1313 35/18639 0.171428571428571 2.43355456424763 0.0337341982979023 0.239629132736823 GO:0061631 ubiquitin conjugating enzyme activity 6/1313 35/18639 0.171428571428571 2.43355456424763 0.0337341982979023 0.239629132736823 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 8/1313 54/18639 0.148148148148148 2.1030718456461 0.0342626433715848 0.240201302688114 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 34/1313 349/18639 0.0974212034383954 1.38296558331169 0.0343647488346035 0.240201302688114 GO:0008276 protein methyltransferase activity 12/1313 95/18639 0.126315789473684 1.79314546839299 0.0345143619396514 0.240201302688114 GO:0140101 catalytic activity, acting on a tRNA 16/1313 139/18639 0.115107913669065 1.63404143402719 0.0355449445350249 0.245713374973662 GO:0019003 GDP binding 10/1313 75/18639 0.133333333333333 1.89276466108149 0.0370277066034806 0.247837572975429 GO:0000510 H3-H4 histone complex chaperone activity 17/1313 151/18639 0.112582781456954 1.59819532640987 0.0371801415260672 0.247837572975429 GO:0140584 chromatin extrusion motor activity 17/1313 151/18639 0.112582781456954 1.59819532640987 0.0371801415260672 0.247837572975429 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 17/1313 151/18639 0.112582781456954 1.59819532640987 0.0371801415260672 0.247837572975429 GO:0140849 ATP-dependent H2AZ histone chaperone activity 17/1313 151/18639 0.112582781456954 1.59819532640987 0.0371801415260672 0.247837572975429 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 3/1313 11/18639 0.272727272727273 3.87156407948487 0.0375365644506475 0.247837572975429 GO:0047676 arachidonate-CoA ligase activity 3/1313 11/18639 0.272727272727273 3.87156407948487 0.0375365644506475 0.247837572975429 GO:0005484 SNAP receptor activity 6/1313 36/18639 0.166666666666667 2.36595582635187 0.0381552466434031 0.250317860144619 GO:0004518 nuclease activity 22/1313 209/18639 0.105263157894737 1.49428789032749 0.0384588878939734 0.250713003359447 GO:0140674 ATP-dependent histone chaperone activity 17/1313 152/18639 0.111842105263158 1.58768088347296 0.0392293898735626 0.254127494149494 GO:0008301 DNA binding, bending 4/1313 19/18639 0.210526315789474 2.98857578065499 0.0405626596656504 0.256894664446058 GO:0046527 glucosyltransferase activity 4/1313 19/18639 0.210526315789474 2.98857578065499 0.0405626596656504 0.256894664446058 GO:0140036 ubiquitin-modified protein reader activity 4/1313 19/18639 0.210526315789474 2.98857578065499 0.0405626596656504 0.256894664446058 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 7/1313 46/18639 0.152173913043478 2.16022053710388 0.0406542041793276 0.256894664446058 GO:0061775 cohesin loader activity 17/1313 153/18639 0.111111111111111 1.57730388423458 0.0413591660867175 0.259755738227555 GO:0003724 RNA helicase activity 10/1313 77/18639 0.12987012987013 1.84360194261184 0.0432518900543141 0.268868253983237 GO:0016866 intramolecular transferase activity 5/1313 28/18639 0.178571428571429 2.53495267109129 0.0435932023448549 0.268868253983237 GO:0046966 nuclear thyroid hormone receptor binding 5/1313 28/18639 0.178571428571429 2.53495267109129 0.0435932023448549 0.268868253983237 GO:0008173 RNA methyltransferase activity 9/1313 67/18639 0.134328358208955 1.90688977049255 0.0445873530509476 0.27025218303111 GO:0042054 histone methyltransferase activity 9/1313 67/18639 0.134328358208955 1.90688977049255 0.0445873530509476 0.27025218303111 GO:0061733 protein-lysine-acetyltransferase activity 7/1313 47/18639 0.148936170212766 2.11425839801656 0.0449813315059226 0.27025218303111 GO:0140938 histone H3 methyltransferase activity 7/1313 47/18639 0.148936170212766 2.11425839801656 0.0449813315059226 0.27025218303111 GO:0016791 phosphatase activity 27/1313 273/18639 0.0989010989010989 1.40397378706594 0.0467702163861032 0.27025218303111 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 18/1313 167/18639 0.107784431137725 1.53007921704193 0.0471032459103235 0.27025218303111 GO:0016423 tRNA (guanine) methyltransferase activity 3/1313 12/18639 0.25 3.5489337395278 0.0474909176006126 0.27025218303111 GO:0016840 carbon-nitrogen lyase activity 3/1313 12/18639 0.25 3.5489337395278 0.0474909176006126 0.27025218303111 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 3/1313 12/18639 0.25 3.5489337395278 0.0474909176006126 0.27025218303111 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 3/1313 12/18639 0.25 3.5489337395278 0.0474909176006126 0.27025218303111 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 3/1313 12/18639 0.25 3.5489337395278 0.0474909176006126 0.27025218303111 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 3/1313 12/18639 0.25 3.5489337395278 0.0474909176006126 0.27025218303111 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/1313 12/18639 0.25 3.5489337395278 0.0474909176006126 0.27025218303111 GO:1990817 poly(A) RNA polymerase activity 3/1313 12/18639 0.25 3.5489337395278 0.0474909176006126 0.27025218303111 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 6/1313 38/18639 0.157894736842105 2.24143183549124 0.0480601226345546 0.271988606118633 GO:0016835 carbon-oxygen lyase activity 10/1313 79/18639 0.126582278481013 1.79692847571028 0.0501514086069365 0.282272955547238 GO:0019210 kinase inhibitor activity 11/1313 90/18639 0.122222222222222 1.73503427265804 0.0511304745987193 0.286219504547179 GO:0016279 protein-lysine N-methyltransferase activity 9/1313 69/18639 0.130434782608696 1.85161760323189 0.0522445773834925 0.290875214621607 GO:0140658 ATP-dependent chromatin remodeler activity 17/1313 158/18639 0.107594936708861 1.52738920435374 0.0532651084717292 0.294962697450974 GO:0031593 polyubiquitin modification-dependent protein binding 8/1313 59/18639 0.135593220338983 1.92484541804898 0.0538256526553468 0.296472846176509 GO:0001222 transcription corepressor binding 7/1313 49/18639 0.142857142857143 2.02796213687303 0.0544937577181823 0.296976563226073 GO:0060590 ATPase regulator activity 7/1313 49/18639 0.142857142857143 2.02796213687303 0.0544937577181823 0.296976563226073 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 4/1313 21/18639 0.19047619047619 2.7039495158307 0.0560673704391904 0.300778081001907 GO:0005123 death receptor binding 4/1313 21/18639 0.19047619047619 2.7039495158307 0.0560673704391904 0.300778081001907 GO:0035613 RNA stem-loop binding 4/1313 21/18639 0.19047619047619 2.7039495158307 0.0560673704391904 0.300778081001907 GO:0016278 lysine N-methyltransferase activity 9/1313 70/18639 0.128571428571429 1.82516592318573 0.0563765866370186 0.300869866508441 GO:0019209 kinase activator activity 16/1313 148/18639 0.108108108108108 1.53467404952553 0.0574025108660809 0.304453409821213 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 8/1313 60/18639 0.133333333333333 1.89276466108149 0.0584468437711388 0.304453409821213 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 3/1313 13/18639 0.230769230769231 3.2759388364872 0.0585960574619715 0.304453409821213 GO:0016922 nuclear receptor binding 15/1313 137/18639 0.109489051094891 1.55427755015816 0.0587944634808239 0.304453409821213 GO:0004532 RNA exonuclease activity 6/1313 40/18639 0.15 2.12936024371668 0.0594127527903533 0.304453409821213 GO:0015036 disulfide oxidoreductase activity 6/1313 40/18639 0.15 2.12936024371668 0.0594127527903533 0.304453409821213 GO:0061791 GTPase motor activity 6/1313 40/18639 0.15 2.12936024371668 0.0594127527903533 0.304453409821213 GO:1990606 membrane scission GTPase motor activity 6/1313 40/18639 0.15 2.12936024371668 0.0594127527903533 0.304453409821213 GO:0035401 histone H3Y41 kinase activity 13/1313 115/18639 0.11304347826087 1.60473525613431 0.0610613355230592 0.309818598959364 GO:0140801 histone H2AXY142 kinase activity 13/1313 115/18639 0.11304347826087 1.60473525613431 0.0610613355230592 0.309818598959364 GO:0051219 phosphoprotein binding 11/1313 93/18639 0.118279569892473 1.67906542515294 0.0620928420919388 0.313507977228906 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 8/1313 61/18639 0.131147540983607 1.8617357322113 0.0633109146079141 0.317318816115864 GO:0016878 acid-thiol ligase activity 5/1313 31/18639 0.161290322580645 2.2896346706631 0.0634637632231728 0.317318816115864 GO:0034062 5'-3' RNA polymerase activity 4/1313 22/18639 0.181818181818182 2.58104271965658 0.0648524243556137 0.317575578772438 GO:0097747 RNA polymerase activity 4/1313 22/18639 0.181818181818182 2.58104271965658 0.0648524243556137 0.317575578772438 GO:0140035 ubiquitin-like protein reader activity 4/1313 22/18639 0.181818181818182 2.58104271965658 0.0648524243556137 0.317575578772438 GO:0140517 protein-RNA adaptor activity 4/1313 22/18639 0.181818181818182 2.58104271965658 0.0648524243556137 0.317575578772438 GO:0140767 enzyme-substrate adaptor activity 15/1313 139/18639 0.107913669064748 1.53191384440049 0.0650567447776548 0.317575578772438 GO:0003712 transcription coregulator activity 44/1313 495/18639 0.0888888888888889 1.26184310738766 0.0657932317487361 0.319655795760369 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 14/1313 128/18639 0.109375 1.55265851104341 0.066698773520204 0.322533975238545 GO:0004713 protein tyrosine kinase activity 15/1313 140/18639 0.107142857142857 1.52097160265477 0.0683496874010518 0.32897279450039 GO:0140713 histone chaperone activity 17/1313 164/18639 0.103658536585366 1.47150911151153 0.0704789686915166 0.334500821147088 GO:0004527 exonuclease activity 10/1313 84/18639 0.119047619047619 1.68996844739419 0.0704888722778389 0.334500821147088 GO:0016530 metallochaperone activity 3/1313 14/18639 0.214285714285714 3.04194320530954 0.0707972611748206 0.334500821147088 GO:0070742 C2H2 zinc finger domain binding 3/1313 14/18639 0.214285714285714 3.04194320530954 0.0707972611748206 0.334500821147088 GO:0140597 protein carrier chaperone 19/1313 188/18639 0.101063829787234 1.43467534151124 0.0714468898642582 0.336028751416374 GO:0004402 histone acetyltransferase activity 6/1313 42/18639 0.142857142857143 2.02796213687303 0.0722297422747535 0.336636355398172 GO:0051879 Hsp90 protein binding 6/1313 42/18639 0.142857142857143 2.02796213687303 0.0722297422747535 0.336636355398172 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 4/1313 23/18639 0.173913043478261 2.46882347097586 0.0743093657761039 0.341690387274049 GO:0043274 phospholipase binding 4/1313 23/18639 0.173913043478261 2.46882347097586 0.0743093657761039 0.341690387274049 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 4/1313 23/18639 0.173913043478261 2.46882347097586 0.0743093657761039 0.341690387274049 GO:0004536 DNA nuclease activity 8/1313 64/18639 0.125 1.7744668697639 0.0793742200907058 0.362522170137106 GO:0060589 nucleoside-triphosphatase regulator activity 43/1313 490/18639 0.0877551020408163 1.24574816979343 0.0798186152891839 0.362522170137106 GO:0050660 flavin adenine dinucleotide binding 10/1313 86/18639 0.116279069767442 1.65066685559433 0.0798956627389545 0.362522170137106 GO:0016874 ligase activity 17/1313 167/18639 0.101796407185629 1.44507481609515 0.0803448528645459 0.362961396712642 GO:0017069 snRNA binding 7/1313 54/18639 0.12962962962963 1.84018786494034 0.0833951810384965 0.369879120337717 GO:0008170 N-methyltransferase activity 11/1313 98/18639 0.112244897959184 1.59339882182881 0.0835636035376456 0.369879120337717 GO:0000774 adenyl-nucleotide exchange factor activity 3/1313 15/18639 0.2 2.83914699162224 0.0840307904456561 0.369879120337717 GO:0004467 long-chain fatty acid-CoA ligase activity 3/1313 15/18639 0.2 2.83914699162224 0.0840307904456561 0.369879120337717 GO:0048531 beta-1,3-galactosyltransferase activity 3/1313 15/18639 0.2 2.83914699162224 0.0840307904456561 0.369879120337717 GO:0140776 protein-containing complex destabilizing activity 3/1313 15/18639 0.2 2.83914699162224 0.0840307904456561 0.369879120337717 GO:0048027 mRNA 5'-UTR binding 4/1313 24/18639 0.166666666666667 2.36595582635187 0.0844201295244432 0.370011631532666 GO:0008175 tRNA methyltransferase activity 5/1313 34/18639 0.147058823529412 2.08760808207518 0.0876327457551091 0.380851173534862 GO:0015035 protein-disulfide reductase activity 5/1313 34/18639 0.147058823529412 2.08760808207518 0.0876327457551091 0.380851173534862 GO:0005085 guanyl-nucleotide exchange factor activity 22/1313 230/18639 0.0956521739130435 1.35785290903672 0.0888660941986861 0.384588558927087 GO:0140303 intramembrane lipid transporter activity 6/1313 45/18639 0.133333333333333 1.89276466108149 0.0941815508300593 0.405887018221595 GO:0017056 structural constituent of nuclear pore 4/1313 25/18639 0.16 2.27131759329779 0.0951627335644269 0.406317228038618 GO:0003727 single-stranded RNA binding 10/1313 89/18639 0.112359550561798 1.59502639978777 0.0953879538992297 0.406317228038618 GO:0005154 epidermal growth factor receptor binding 5/1313 35/18639 0.142857142857143 2.02796213687303 0.0966158369979769 0.406317228038618 GO:0043015 gamma-tubulin binding 5/1313 35/18639 0.142857142857143 2.02796213687303 0.0966158369979769 0.406317228038618 GO:0140566 histone reader activity 5/1313 35/18639 0.142857142857143 2.02796213687303 0.0966158369979769 0.406317228038618 GO:0140789 histone phosphatase activity 14/1313 136/18639 0.102941176470588 1.46132565745262 0.0981494568723726 0.406317228038618 GO:0005521 lamin binding 3/1313 16/18639 0.1875 2.66170030464585 0.0982262036714718 0.406317228038618 GO:0015923 mannosidase activity 3/1313 16/18639 0.1875 2.66170030464585 0.0982262036714718 0.406317228038618 GO:0017070 U6 snRNA binding 3/1313 16/18639 0.1875 2.66170030464585 0.0982262036714718 0.406317228038618 GO:0043023 ribosomal large subunit binding 3/1313 16/18639 0.1875 2.66170030464585 0.0982262036714718 0.406317228038618 GO:0030695 GTPase regulator activity 42/1313 489/18639 0.0858895705521472 1.21926557922427 0.105499705110857 0.434658785056732 GO:0070006 metalloaminopeptidase activity 4/1313 26/18639 0.153846153846154 2.1839592243248 0.106511764774557 0.437080150270095 GO:0000049 tRNA binding 9/1313 80/18639 0.1125 1.59702018278751 0.109181498551004 0.446257712331486 GO:0008080 N-acetyltransferase activity 8/1313 69/18639 0.115942028985507 1.64588231398391 0.111042594117576 0.447155491958287 GO:0004519 endonuclease activity 13/1313 127/18639 0.102362204724409 1.45310672799563 0.111588426754615 0.447155491958287 GO:0008408 3'-5' exonuclease activity 7/1313 58/18639 0.120689655172414 1.71327835701342 0.111769562230888 0.447155491958287 GO:0017116 single-stranded DNA helicase activity 7/1313 58/18639 0.120689655172414 1.71327835701342 0.111769562230888 0.447155491958287 GO:0030295 protein kinase activator activity 14/1313 139/18639 0.100719424460432 1.42978625477379 0.111953926096243 0.447155491958287 GO:0004549 tRNA-specific ribonuclease activity 3/1313 17/18639 0.176470588235294 2.50512969849021 0.113308333399139 0.447155491958287 GO:0004659 prenyltransferase activity 3/1313 17/18639 0.176470588235294 2.50512969849021 0.113308333399139 0.447155491958287 GO:0051787 misfolded protein binding 3/1313 17/18639 0.176470588235294 2.50512969849021 0.113308333399139 0.447155491958287 GO:0070402 NADPH binding 3/1313 17/18639 0.176470588235294 2.50512969849021 0.113308333399139 0.447155491958287 GO:0023023 MHC protein complex binding 5/1313 37/18639 0.135135135135135 1.91834256190692 0.115906887533715 0.455664481525673 GO:0005525 GTP binding 33/1313 378/18639 0.0873015873015873 1.23931019475574 0.118401865008566 0.462090979465093 GO:0001671 ATPase activator activity 4/1313 27/18639 0.148148148148148 2.1030718456461 0.118438852989111 0.462090979465093 GO:0036002 pre-mRNA binding 7/1313 59/18639 0.11864406779661 1.68423974079285 0.119569703904518 0.464742622723222 GO:0035591 signaling adaptor activity 13/1313 129/18639 0.10077519379845 1.43057794151508 0.121869098731599 0.471899141705063 GO:0016763 pentosyltransferase activity 6/1313 49/18639 0.122448979591837 1.73825326017688 0.128341453394974 0.489246094015213 GO:0008135 translation factor activity, RNA binding 9/1313 83/18639 0.108433734939759 1.5392965617229 0.129076078765568 0.489246094015213 GO:0000400 four-way junction DNA binding 3/1313 18/18639 0.166666666666667 2.36595582635187 0.129198968516639 0.489246094015213 GO:0003746 translation elongation factor activity 3/1313 18/18639 0.166666666666667 2.36595582635187 0.129198968516639 0.489246094015213 GO:0008409 5'-3' exonuclease activity 3/1313 18/18639 0.166666666666667 2.36595582635187 0.129198968516639 0.489246094015213 GO:0017128 phospholipid scramblase activity 3/1313 18/18639 0.166666666666667 2.36595582635187 0.129198968516639 0.489246094015213 GO:0051019 mitogen-activated protein kinase binding 4/1313 28/18639 0.142857142857143 2.02796213687303 0.130913128096487 0.493921325785282 GO:0180051 translation factor activity 9/1313 84/18639 0.107142857142857 1.52097160265477 0.136106543544096 0.511641386315397 GO:0015605 organophosphate ester transmembrane transporter activity 6/1313 50/18639 0.12 1.70348819497334 0.137703596221386 0.513893855463867 GO:0032813 tumor necrosis factor receptor superfamily binding 6/1313 50/18639 0.12 1.70348819497334 0.137703596221386 0.513893855463867 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 4/1313 29/18639 0.137931034482759 1.95803240801534 0.143901656217317 0.532598669216258 GO:0097472 cyclin-dependent protein kinase activity 4/1313 29/18639 0.137931034482759 1.95803240801534 0.143901656217317 0.532598669216258 GO:0004540 RNA nuclease activity 12/1313 121/18639 0.0991735537190083 1.40784148344904 0.144785428758529 0.532598669216258 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/1313 19/18639 0.157894736842105 2.24143183549124 0.145818276426199 0.532598669216258 GO:0008574 plus-end-directed microtubule motor activity 3/1313 19/18639 0.157894736842105 2.24143183549124 0.145818276426199 0.532598669216258 GO:0120227 acyl-CoA binding 3/1313 19/18639 0.157894736842105 2.24143183549124 0.145818276426199 0.532598669216258 GO:0016830 carbon-carbon lyase activity 6/1313 51/18639 0.117647058823529 1.67008646566014 0.147374581590633 0.533308095773419 GO:0004177 aminopeptidase activity 5/1313 40/18639 0.125 1.7744668697639 0.147933030821945 0.533308095773419 GO:0030331 nuclear estrogen receptor binding 5/1313 40/18639 0.125 1.7744668697639 0.147933030821945 0.533308095773419 GO:0031491 nucleosome binding 8/1313 74/18639 0.108108108108108 1.53467404952553 0.148596906287015 0.533308095773419 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 12/1313 122/18639 0.0983606557377049 1.39630179915848 0.150957200756219 0.533308095773419 GO:0042393 histone binding 22/1313 247/18639 0.0890688259109312 1.26439744566173 0.152325804867453 0.533308095773419 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 2/1313 10/18639 0.2 2.83914699162224 0.153261355678575 0.533308095773419 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 2/1313 10/18639 0.2 2.83914699162224 0.153261355678575 0.533308095773419 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/1313 10/18639 0.2 2.83914699162224 0.153261355678575 0.533308095773419 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/1313 10/18639 0.2 2.83914699162224 0.153261355678575 0.533308095773419 GO:0030957 Tat protein binding 2/1313 10/18639 0.2 2.83914699162224 0.153261355678575 0.533308095773419 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/1313 10/18639 0.2 2.83914699162224 0.153261355678575 0.533308095773419 GO:0033204 ribonuclease P RNA binding 2/1313 10/18639 0.2 2.83914699162224 0.153261355678575 0.533308095773419 GO:0097177 mitochondrial ribosome binding 2/1313 10/18639 0.2 2.83914699162224 0.153261355678575 0.533308095773419 GO:0001965 G-protein alpha-subunit binding 4/1313 30/18639 0.133333333333333 1.89276466108149 0.157369852029196 0.545760766296537 GO:0042169 SH2 domain binding 5/1313 41/18639 0.121951219512195 1.73118719001356 0.159362887620132 0.548975833607814 GO:0042287 MHC protein binding 5/1313 41/18639 0.121951219512195 1.73118719001356 0.159362887620132 0.548975833607814 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 3/1313 20/18639 0.15 2.12936024371668 0.163085996709181 0.55256110727124 GO:0016004 phospholipase activator activity 3/1313 20/18639 0.15 2.12936024371668 0.163085996709181 0.55256110727124 GO:0016408 C-acyltransferase activity 3/1313 20/18639 0.15 2.12936024371668 0.163085996709181 0.55256110727124 GO:0042288 MHC class I protein binding 3/1313 20/18639 0.15 2.12936024371668 0.163085996709181 0.55256110727124 GO:0052745 inositol phosphate phosphatase activity 3/1313 20/18639 0.15 2.12936024371668 0.163085996709181 0.55256110727124 GO:0004197 cysteine-type endopeptidase activity 9/1313 88/18639 0.102272727272727 1.45183652980683 0.166127617598174 0.561021134839735 GO:0004721 phosphoprotein phosphatase activity 16/1313 175/18639 0.0914285714285714 1.29789576759874 0.17150067539909 0.568973195154293 GO:0019843 rRNA binding 7/1313 65/18639 0.107692307692308 1.52877145702736 0.171856253971203 0.568973195154293 GO:0003925 G protein activity 6/1313 54/18639 0.111111111111111 1.57730388423458 0.17812114106824 0.568973195154293 GO:0051287 NAD binding 6/1313 54/18639 0.111111111111111 1.57730388423458 0.17812114106824 0.568973195154293 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0002162 dystroglycan binding 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0004143 ATP-dependent diacylglycerol kinase activity 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0008432 JUN kinase binding 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0019107 myristoyltransferase activity 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0032404 mismatch repair complex binding 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0043522 leucine zipper domain binding 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0045294 alpha-catenin binding 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0140031 phosphorylation-dependent protein binding 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0180030 inositol phosphate kinase activity 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:1990948 ubiquitin ligase inhibitor activity 2/1313 11/18639 0.181818181818182 2.58104271965658 0.178977975951447 0.568973195154293 GO:0003924 GTPase activity 28/1313 331/18639 0.0845921450151057 1.20084767017255 0.180678046116759 0.569878004444868 GO:0009931 calcium-dependent protein serine/threonine kinase activity 3/1313 21/18639 0.142857142857143 2.02796213687303 0.180922434420847 0.569878004444868 GO:1904047 S-adenosyl-L-methionine binding 3/1313 21/18639 0.142857142857143 2.02796213687303 0.180922434420847 0.569878004444868 GO:0048156 tau protein binding 5/1313 43/18639 0.116279069767442 1.65066685559433 0.183236494133845 0.575407283408111 GO:0043425 bHLH transcription factor binding 4/1313 32/18639 0.125 1.7744668697639 0.185600939515032 0.579299902122675 GO:0051059 NF-kappaB binding 4/1313 32/18639 0.125 1.7744668697639 0.185600939515032 0.579299902122675 GO:0001221 transcription coregulator binding 11/1313 115/18639 0.0956521739130435 1.35785290903672 0.186448143019913 0.580186064382206 GO:0019001 guanyl nucleotide binding 33/1313 400/18639 0.0825 1.17114813404417 0.194440246429258 0.601421783249658 GO:0032561 guanyl ribonucleotide binding 33/1313 400/18639 0.0825 1.17114813404417 0.194440246429258 0.601421783249658 GO:0001046 core promoter sequence-specific DNA binding 5/1313 44/18639 0.113636363636364 1.61315169978536 0.195637971179061 0.601513762132636 GO:0043014 alpha-tubulin binding 5/1313 44/18639 0.113636363636364 1.61315169978536 0.195637971179061 0.601513762132636 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 3/1313 22/18639 0.136363636363636 1.93578203974244 0.199249278115357 0.603984114701249 GO:0061133 endopeptidase activator activity 3/1313 22/18639 0.136363636363636 1.93578203974244 0.199249278115357 0.603984114701249 GO:0140416 transcription regulator inhibitor activity 4/1313 33/18639 0.121212121212121 1.72069514643772 0.200289744299275 0.603984114701249 GO:0000995 RNA polymerase III general transcription initiation factor activity 2/1313 12/18639 0.166666666666667 2.36595582635187 0.205275387621614 0.603984114701249 GO:0003995 acyl-CoA dehydrogenase activity 2/1313 12/18639 0.166666666666667 2.36595582635187 0.205275387621614 0.603984114701249 GO:0004526 ribonuclease P activity 2/1313 12/18639 0.166666666666667 2.36595582635187 0.205275387621614 0.603984114701249 GO:0005095 GTPase inhibitor activity 2/1313 12/18639 0.166666666666667 2.36595582635187 0.205275387621614 0.603984114701249 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/1313 12/18639 0.166666666666667 2.36595582635187 0.205275387621614 0.603984114701249 GO:0016273 arginine N-methyltransferase activity 2/1313 12/18639 0.166666666666667 2.36595582635187 0.205275387621614 0.603984114701249 GO:0016274 protein-arginine N-methyltransferase activity 2/1313 12/18639 0.166666666666667 2.36595582635187 0.205275387621614 0.603984114701249 GO:0035197 siRNA binding 2/1313 12/18639 0.166666666666667 2.36595582635187 0.205275387621614 0.603984114701249 GO:0045295 gamma-catenin binding 2/1313 12/18639 0.166666666666667 2.36595582635187 0.205275387621614 0.603984114701249 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 2/1313 12/18639 0.166666666666667 2.36595582635187 0.205275387621614 0.603984114701249 GO:0070679 inositol 1,4,5 trisphosphate binding 2/1313 12/18639 0.166666666666667 2.36595582635187 0.205275387621614 0.603984114701249 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 2/1313 12/18639 0.166666666666667 2.36595582635187 0.205275387621614 0.603984114701249 GO:0033192 calmodulin-dependent protein phosphatase activity 8/1313 81/18639 0.0987654320987654 1.4020478970974 0.209928459284512 0.603984114701249 GO:0140791 histone H2AXS140 phosphatase activity 8/1313 81/18639 0.0987654320987654 1.4020478970974 0.209928459284512 0.603984114701249 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 8/1313 81/18639 0.0987654320987654 1.4020478970974 0.209928459284512 0.603984114701249 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 8/1313 81/18639 0.0987654320987654 1.4020478970974 0.209928459284512 0.603984114701249 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 8/1313 81/18639 0.0987654320987654 1.4020478970974 0.209928459284512 0.603984114701249 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 8/1313 81/18639 0.0987654320987654 1.4020478970974 0.209928459284512 0.603984114701249 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 8/1313 81/18639 0.0987654320987654 1.4020478970974 0.209928459284512 0.603984114701249 GO:1990439 MAP kinase serine/threonine phosphatase activity 8/1313 81/18639 0.0987654320987654 1.4020478970974 0.209928459284512 0.603984114701249 GO:0000149 SNARE binding 10/1313 106/18639 0.0943396226415094 1.33922027906709 0.212789287510623 0.610509654974768 GO:0008376 acetylgalactosaminyltransferase activity 4/1313 34/18639 0.117647058823529 1.67008646566014 0.215310677438497 0.612624303208984 GO:0030332 cyclin binding 4/1313 34/18639 0.117647058823529 1.67008646566014 0.215310677438497 0.612624303208984 GO:0052866 phosphatidylinositol phosphate phosphatase activity 4/1313 34/18639 0.117647058823529 1.67008646566014 0.215310677438497 0.612624303208984 GO:0003887 DNA-directed DNA polymerase activity 3/1313 23/18639 0.130434782608696 1.85161760323189 0.217990264966245 0.615150610726665 GO:0008171 O-methyltransferase activity 3/1313 23/18639 0.130434782608696 1.85161760323189 0.217990264966245 0.615150610726665 GO:0140103 catalytic activity, acting on a glycoprotein 3/1313 23/18639 0.130434782608696 1.85161760323189 0.217990264966245 0.615150610726665 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 8/1313 82/18639 0.0975609756097561 1.38494975201085 0.21940796107436 0.615777111462101 GO:0033549 MAP kinase phosphatase activity 8/1313 82/18639 0.0975609756097561 1.38494975201085 0.21940796107436 0.615777111462101 GO:0030291 protein serine/threonine kinase inhibitor activity 5/1313 46/18639 0.108695652173913 1.54301466935991 0.221260190905005 0.61928803432651 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 8/1313 83/18639 0.0963855421686747 1.36826361042036 0.229043361853965 0.627041174393165 GO:0010485 histone H4 acetyltransferase activity 4/1313 35/18639 0.114285714285714 1.62236970949842 0.230626140721145 0.627041174393165 GO:0034061 DNA polymerase activity 4/1313 35/18639 0.114285714285714 1.62236970949842 0.230626140721145 0.627041174393165 GO:0004535 poly(A)-specific ribonuclease activity 2/1313 13/18639 0.153846153846154 2.1839592243248 0.231944356741549 0.627041174393165 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/1313 13/18639 0.153846153846154 2.1839592243248 0.231944356741549 0.627041174393165 GO:0005338 nucleotide-sugar transmembrane transporter activity 2/1313 13/18639 0.153846153846154 2.1839592243248 0.231944356741549 0.627041174393165 GO:0035325 Toll-like receptor binding 2/1313 13/18639 0.153846153846154 2.1839592243248 0.231944356741549 0.627041174393165 GO:0035673 oligopeptide transmembrane transporter activity 2/1313 13/18639 0.153846153846154 2.1839592243248 0.231944356741549 0.627041174393165 GO:0046974 histone H3K9 methyltransferase activity 2/1313 13/18639 0.153846153846154 2.1839592243248 0.231944356741549 0.627041174393165 GO:0051011 microtubule minus-end binding 2/1313 13/18639 0.153846153846154 2.1839592243248 0.231944356741549 0.627041174393165 GO:0089720 caspase binding 2/1313 13/18639 0.153846153846154 2.1839592243248 0.231944356741549 0.627041174393165 GO:0097157 pre-mRNA intronic binding 2/1313 13/18639 0.153846153846154 2.1839592243248 0.231944356741549 0.627041174393165 GO:0140410 monoatomic cation:bicarbonate symporter activity 2/1313 13/18639 0.153846153846154 2.1839592243248 0.231944356741549 0.627041174393165 GO:0001091 RNA polymerase II general transcription initiation factor binding 3/1313 24/18639 0.125 1.7744668697639 0.237071712886503 0.6375557813919 GO:0060229 lipase activator activity 3/1313 24/18639 0.125 1.7744668697639 0.237071712886503 0.6375557813919 GO:0017018 myosin phosphatase activity 8/1313 84/18639 0.0952380952380952 1.35197475791535 0.238826184833951 0.640601485361899 GO:0008234 cysteine-type peptidase activity 16/1313 187/18639 0.0855614973262032 1.21460833866192 0.24481686710203 0.654964605493742 GO:0055106 ubiquitin-protein transferase regulator activity 4/1313 36/18639 0.111111111111111 1.57730388423458 0.246198787751973 0.656955314467701 GO:0005537 D-mannose binding 3/1313 25/18639 0.12 1.70348819497334 0.256422937339513 0.661454769684246 GO:0015645 fatty acid ligase activity 3/1313 25/18639 0.12 1.70348819497334 0.256422937339513 0.661454769684246 GO:0015662 P-type ion transporter activity 3/1313 25/18639 0.12 1.70348819497334 0.256422937339513 0.661454769684246 GO:0120515 fatty acid-CoA ligase activity 3/1313 25/18639 0.12 1.70348819497334 0.256422937339513 0.661454769684246 GO:0140358 P-type transmembrane transporter activity 3/1313 25/18639 0.12 1.70348819497334 0.256422937339513 0.661454769684246 GO:0004705 JUN kinase activity 2/1313 14/18639 0.142857142857143 2.02796213687303 0.258802206002671 0.661454769684246 GO:0005545 1-phosphatidylinositol binding 2/1313 14/18639 0.142857142857143 2.02796213687303 0.258802206002671 0.661454769684246 GO:0008191 metalloendopeptidase inhibitor activity 2/1313 14/18639 0.142857142857143 2.02796213687303 0.258802206002671 0.661454769684246 GO:0008474 palmitoyl-(protein) hydrolase activity 2/1313 14/18639 0.142857142857143 2.02796213687303 0.258802206002671 0.661454769684246 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/1313 14/18639 0.142857142857143 2.02796213687303 0.258802206002671 0.661454769684246 GO:0030983 mismatched DNA binding 2/1313 14/18639 0.142857142857143 2.02796213687303 0.258802206002671 0.661454769684246 GO:0034236 protein kinase A catalytic subunit binding 2/1313 14/18639 0.142857142857143 2.02796213687303 0.258802206002671 0.661454769684246 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 2/1313 14/18639 0.142857142857143 2.02796213687303 0.258802206002671 0.661454769684246 GO:0044548 S100 protein binding 2/1313 14/18639 0.142857142857143 2.02796213687303 0.258802206002671 0.661454769684246 GO:0046030 inositol trisphosphate phosphatase activity 2/1313 14/18639 0.142857142857143 2.02796213687303 0.258802206002671 0.661454769684246 GO:0098599 palmitoyl hydrolase activity 2/1313 14/18639 0.142857142857143 2.02796213687303 0.258802206002671 0.661454769684246 GO:1990825 sequence-specific mRNA binding 2/1313 14/18639 0.142857142857143 2.02796213687303 0.258802206002671 0.661454769684246 GO:0019902 phosphatase binding 16/1313 190/18639 0.0842105263157895 1.195430312262 0.264879669944189 0.675312029808204 GO:0005112 Notch binding 3/1313 26/18639 0.115384615384615 1.6379694182436 0.275976568543638 0.69841736019643 GO:0034237 protein kinase A regulatory subunit binding 3/1313 26/18639 0.115384615384615 1.6379694182436 0.275976568543638 0.69841736019643 GO:0097602 cullin family protein binding 3/1313 26/18639 0.115384615384615 1.6379694182436 0.275976568543638 0.69841736019643 GO:0042887 amide transmembrane transporter activity 4/1313 38/18639 0.105263157894737 1.49428789032749 0.27796880946677 0.701734984683268 GO:0003774 cytoskeletal motor activity 13/1313 153/18639 0.0849673202614379 1.20617355853232 0.281766659361011 0.709583518684209 GO:0004559 alpha-mannosidase activity 2/1313 15/18639 0.133333333333333 1.89276466108149 0.285690116088366 0.71077492650004 GO:0004953 icosanoid receptor activity 2/1313 15/18639 0.133333333333333 1.89276466108149 0.285690116088366 0.71077492650004 GO:0010181 FMN binding 2/1313 15/18639 0.133333333333333 1.89276466108149 0.285690116088366 0.71077492650004 GO:0047372 monoacylglycerol lipase activity 2/1313 15/18639 0.133333333333333 1.89276466108149 0.285690116088366 0.71077492650004 GO:0061578 K63-linked deubiquitinase activity 2/1313 15/18639 0.133333333333333 1.89276466108149 0.285690116088366 0.71077492650004 GO:0003743 translation initiation factor activity 5/1313 51/18639 0.0980392156862745 1.39173872138345 0.289033589808698 0.717034711239147 GO:0005506 iron ion binding 13/1313 154/18639 0.0844155844155844 1.1983412626977 0.289598485316005 0.717034711239147 GO:0017124 SH3 domain binding 10/1313 115/18639 0.0869565217391304 1.23441173548793 0.291342393961147 0.719622699712186 GO:0016405 CoA-ligase activity 3/1313 27/18639 0.111111111111111 1.57730388423458 0.295668782987953 0.72682302261955 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/1313 27/18639 0.111111111111111 1.57730388423458 0.295668782987953 0.72682302261955 GO:0004722 protein serine/threonine phosphatase activity 9/1313 103/18639 0.087378640776699 1.24040402546603 0.300701570220508 0.737434803159817 GO:0071949 FAD binding 4/1313 40/18639 0.1 1.41957349581112 0.310334792922388 0.75022096796088 GO:0000062 fatty-acyl-CoA binding 2/1313 16/18639 0.125 1.7744668697639 0.312470675005065 0.75022096796088 GO:0004707 MAP kinase activity 2/1313 16/18639 0.125 1.7744668697639 0.312470675005065 0.75022096796088 GO:0004708 MAP kinase kinase activity 2/1313 16/18639 0.125 1.7744668697639 0.312470675005065 0.75022096796088 GO:0005159 insulin-like growth factor receptor binding 2/1313 16/18639 0.125 1.7744668697639 0.312470675005065 0.75022096796088 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1313 16/18639 0.125 1.7744668697639 0.312470675005065 0.75022096796088 GO:0016722 oxidoreductase activity, acting on metal ions 2/1313 16/18639 0.125 1.7744668697639 0.312470675005065 0.75022096796088 GO:0030275 LRR domain binding 2/1313 16/18639 0.125 1.7744668697639 0.312470675005065 0.75022096796088 GO:0140327 flippase activity 2/1313 16/18639 0.125 1.7744668697639 0.312470675005065 0.75022096796088 GO:0019789 SUMO transferase activity 3/1313 28/18639 0.107142857142857 1.52097160265477 0.315439461574929 0.752353811196531 GO:0051537 2 iron, 2 sulfur cluster binding 3/1313 28/18639 0.107142857142857 1.52097160265477 0.315439461574929 0.752353811196531 GO:0019903 protein phosphatase binding 12/1313 144/18639 0.0833333333333333 1.18297791317593 0.315550336346506 0.752353811196531 GO:0051018 protein kinase A binding 5/1313 53/18639 0.0943396226415094 1.33922027906709 0.31715232841057 0.754427016773411 GO:0001727 lipid kinase activity 4/1313 41/18639 0.0975609756097561 1.38494975201085 0.326656079982092 0.771687528398061 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/1313 41/18639 0.0975609756097561 1.38494975201085 0.326656079982092 0.771687528398061 GO:0008137 NADH dehydrogenase (ubiquinone) activity 4/1313 41/18639 0.0975609756097561 1.38494975201085 0.326656079982092 0.771687528398061 GO:0030246 carbohydrate binding 22/1313 280/18639 0.0785714285714286 1.11537917528017 0.328280005476762 0.773749211993283 GO:0010484 histone H3 acetyltransferase activity 3/1313 29/18639 0.103448275862069 1.4685243060115 0.335232285270039 0.786478431311783 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/1313 29/18639 0.103448275862069 1.4685243060115 0.335232285270039 0.786478431311783 GO:0042578 phosphoric ester hydrolase activity 28/1313 363/18639 0.0771349862258953 1.09498782046037 0.336016832467027 0.786478431311783 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/1313 17/18639 0.117647058823529 1.67008646566014 0.339025653885856 0.786478431311783 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/1313 17/18639 0.117647058823529 1.67008646566014 0.339025653885856 0.786478431311783 GO:0005092 GDP-dissociation inhibitor activity 2/1313 17/18639 0.117647058823529 1.67008646566014 0.339025653885856 0.786478431311783 GO:1901567 fatty acid derivative binding 2/1313 17/18639 0.117647058823529 1.67008646566014 0.339025653885856 0.786478431311783 GO:0016410 N-acyltransferase activity 8/1313 94/18639 0.0851063829787234 1.20814765600946 0.342798841794275 0.793444510220457 GO:0140313 molecular sequestering activity 5/1313 55/18639 0.0909090909090909 1.29052135982829 0.345582650133528 0.794890408619629 GO:0005548 phospholipid transporter activity 6/1313 68/18639 0.0882352941176471 1.25256484924511 0.345738740836499 0.794890408619629 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 6/1313 68/18639 0.0882352941176471 1.25256484924511 0.345738740836499 0.794890408619629 GO:0035091 phosphatidylinositol binding 22/1313 284/18639 0.0774647887323944 1.09966960943115 0.352925198599182 0.807162519178642 GO:0015215 nucleotide transmembrane transporter activity 3/1313 30/18639 0.1 1.41957349581112 0.354994777852354 0.807162519178642 GO:0016769 transferase activity, transferring nitrogenous groups 3/1313 30/18639 0.1 1.41957349581112 0.354994777852354 0.807162519178642 GO:0031624 ubiquitin conjugating enzyme binding 3/1313 30/18639 0.1 1.41957349581112 0.354994777852354 0.807162519178642 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/1313 30/18639 0.1 1.41957349581112 0.354994777852354 0.807162519178642 GO:0005096 GTPase activator activity 21/1313 271/18639 0.0774907749077491 1.10003850228906 0.357024696145773 0.807321049879222 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4/1313 43/18639 0.0930232558139535 1.32053348447546 0.359415155045101 0.807321049879222 GO:0002020 protease binding 11/1313 136/18639 0.0808823529411765 1.14818444514135 0.362389768742293 0.807321049879222 GO:0000900 mRNA regulatory element binding translation repressor activity 2/1313 18/18639 0.111111111111111 1.57730388423458 0.365253989557007 0.807321049879222 GO:0004706 JUN kinase kinase kinase activity 2/1313 18/18639 0.111111111111111 1.57730388423458 0.365253989557007 0.807321049879222 GO:0016854 racemase and epimerase activity 2/1313 18/18639 0.111111111111111 1.57730388423458 0.365253989557007 0.807321049879222 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/1313 18/18639 0.111111111111111 1.57730388423458 0.365253989557007 0.807321049879222 GO:0017075 syntaxin-1 binding 2/1313 18/18639 0.111111111111111 1.57730388423458 0.365253989557007 0.807321049879222 GO:0031690 adrenergic receptor binding 2/1313 18/18639 0.111111111111111 1.57730388423458 0.365253989557007 0.807321049879222 GO:0035615 clathrin adaptor activity 2/1313 18/18639 0.111111111111111 1.57730388423458 0.365253989557007 0.807321049879222 GO:0050811 GABA receptor binding 2/1313 18/18639 0.111111111111111 1.57730388423458 0.365253989557007 0.807321049879222 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/1313 18/18639 0.111111111111111 1.57730388423458 0.365253989557007 0.807321049879222 GO:1990381 ubiquitin-specific protease binding 2/1313 18/18639 0.111111111111111 1.57730388423458 0.365253989557007 0.807321049879222 GO:0016782 transferase activity, transferring sulphur-containing groups 6/1313 70/18639 0.0857142857142857 1.21677728212382 0.371367458745968 0.81832274764198 GO:0015932 nucleobase-containing compound transmembrane transporter activity 5/1313 57/18639 0.087719298245614 1.24523990860625 0.374157615418805 0.81832274764198 GO:0016504 peptidase activator activity 5/1313 57/18639 0.087719298245614 1.24523990860625 0.374157615418805 0.81832274764198 GO:0005164 tumor necrosis factor receptor binding 3/1313 31/18639 0.0967741935483871 1.37378080239786 0.374678304209502 0.81832274764198 GO:0001223 transcription coactivator binding 4/1313 44/18639 0.0909090909090909 1.29052135982829 0.375792873431705 0.81832274764198 GO:0003954 NADH dehydrogenase activity 4/1313 44/18639 0.0909090909090909 1.29052135982829 0.375792873431705 0.81832274764198 GO:0019205 nucleobase-containing compound kinase activity 4/1313 44/18639 0.0909090909090909 1.29052135982829 0.375792873431705 0.81832274764198 GO:0061980 regulatory RNA binding 5/1313 58/18639 0.0862068965517241 1.22377025500959 0.388449797795187 0.838977629213718 GO:0070851 growth factor receptor binding 11/1313 139/18639 0.079136690647482 1.12340348589369 0.389755599820664 0.838977629213718 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 2/1313 19/18639 0.105263157894737 1.49428789032749 0.39106995580769 0.838977629213718 GO:0008381 mechanosensitive monoatomic ion channel activity 2/1313 19/18639 0.105263157894737 1.49428789032749 0.39106995580769 0.838977629213718 GO:0015245 fatty acid transmembrane transporter activity 2/1313 19/18639 0.105263157894737 1.49428789032749 0.39106995580769 0.838977629213718 GO:1990380 K48-linked deubiquitinase activity 2/1313 19/18639 0.105263157894737 1.49428789032749 0.39106995580769 0.838977629213718 GO:0008009 chemokine activity 4/1313 45/18639 0.0888888888888889 1.26184310738766 0.392131688037463 0.838977629213718 GO:0030515 snoRNA binding 3/1313 32/18639 0.09375 1.33085015232292 0.394238031591689 0.838977629213718 GO:0031369 translation initiation factor binding 3/1313 32/18639 0.09375 1.33085015232292 0.394238031591689 0.838977629213718 GO:0070717 poly-purine tract binding 3/1313 32/18639 0.09375 1.33085015232292 0.394238031591689 0.838977629213718 GO:0120015 sterol transfer activity 3/1313 32/18639 0.09375 1.33085015232292 0.394238031591689 0.838977629213718 GO:0019783 ubiquitin-like protein peptidase activity 10/1313 127/18639 0.078740157480315 1.11777440615049 0.405142946301791 0.860245847869761 GO:0045296 cadherin binding 25/1313 334/18639 0.0748502994011976 1.06255501183467 0.405902409771557 0.860245847869761 GO:0030296 protein tyrosine kinase activator activity 3/1313 33/18639 0.0909090909090909 1.29052135982829 0.41363286032093 0.867593895013574 GO:0071889 14-3-3 protein binding 3/1313 33/18639 0.0909090909090909 1.29052135982829 0.41363286032093 0.867593895013574 GO:0140311 protein sequestering activity 3/1313 33/18639 0.0909090909090909 1.29052135982829 0.41363286032093 0.867593895013574 GO:0031490 chromatin DNA binding 10/1313 128/18639 0.078125 1.10904179360244 0.414802337353604 0.867593895013574 GO:0001972 retinoic acid binding 2/1313 20/18639 0.1 1.41957349581112 0.416401506818635 0.867593895013574 GO:0061608 nuclear import signal receptor activity 2/1313 20/18639 0.1 1.41957349581112 0.416401506818635 0.867593895013574 GO:0140664 ATP-dependent DNA damage sensor activity 2/1313 20/18639 0.1 1.41957349581112 0.416401506818635 0.867593895013574 GO:0140939 histone H4 methyltransferase activity 2/1313 20/18639 0.1 1.41957349581112 0.416401506818635 0.867593895013574 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 5/1313 60/18639 0.0833333333333333 1.18297791317593 0.416950464108465 0.867593895013574 GO:0101005 deubiquitinase activity 9/1313 115/18639 0.0782608695652174 1.11097056193914 0.422027650896195 0.875995037882124 GO:0035064 methylated histone binding 6/1313 74/18639 0.0810810810810811 1.15100553714415 0.422688867793608 0.875995037882124 GO:0001784 phosphotyrosine residue binding 4/1313 47/18639 0.0851063829787234 1.20814765600946 0.424588367256874 0.876404846241644 GO:1990518 single-stranded 3'-5' DNA helicase activity 4/1313 47/18639 0.0851063829787234 1.20814765600946 0.424588367256874 0.876404846241644 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 20/1313 268/18639 0.0746268656716418 1.05938320582919 0.427775930857372 0.881218417566186 GO:0019905 syntaxin binding 5/1313 61/18639 0.0819672131147541 1.16358483263207 0.43112393080178 0.884094243045275 GO:0009055 electron transfer activity 9/1313 116/18639 0.0775862068965517 1.10139322950863 0.432246069799984 0.884094243045275 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 3/1313 34/18639 0.0882352941176471 1.25256484924511 0.432825329632133 0.884094243045275 GO:0016831 carboxy-lyase activity 3/1313 34/18639 0.0882352941176471 1.25256484924511 0.432825329632133 0.884094243045275 GO:0016798 hydrolase activity, acting on glycosyl bonds 10/1313 130/18639 0.0769230769230769 1.0919796121624 0.434112987498204 0.884094243045275 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 7/1313 89/18639 0.0786516853932584 1.11651847985144 0.438509051985241 0.884094243045275 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 7/1313 89/18639 0.0786516853932584 1.11651847985144 0.438509051985241 0.884094243045275 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/1313 48/18639 0.0833333333333333 1.18297791317593 0.440657879345953 0.884094243045275 GO:0043138 3'-5' DNA helicase activity 4/1313 48/18639 0.0833333333333333 1.18297791317593 0.440657879345953 0.884094243045275 GO:0140693 molecular condensate scaffold activity 4/1313 48/18639 0.0833333333333333 1.18297791317593 0.440657879345953 0.884094243045275 GO:0001846 opsonin binding 2/1313 21/18639 0.0952380952380952 1.35197475791535 0.441188777597351 0.884094243045275 GO:0009975 cyclase activity 2/1313 21/18639 0.0952380952380952 1.35197475791535 0.441188777597351 0.884094243045275 GO:0070182 DNA polymerase binding 2/1313 21/18639 0.0952380952380952 1.35197475791535 0.441188777597351 0.884094243045275 GO:0140312 cargo adaptor activity 2/1313 21/18639 0.0952380952380952 1.35197475791535 0.441188777597351 0.884094243045275 GO:0019208 phosphatase regulator activity 9/1313 117/18639 0.0769230769230769 1.0919796121624 0.442448756145939 0.884897512291878 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 17/1313 229/18639 0.074235807860262 1.05383185278555 0.447572436860307 0.891725807034067 GO:0140034 methylation-dependent protein binding 6/1313 76/18639 0.0789473684210526 1.12071591774562 0.448168393605545 0.891725807034067 GO:0140793 histone H2AXY142 phosphatase activity 7/1313 90/18639 0.0777777777777778 1.1041127189642 0.450180065591416 0.891725807034067 GO:0022853 active monoatomic ion transmembrane transporter activity 9/1313 118/18639 0.076271186440678 1.08272554765255 0.452629247116778 0.891725807034067 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 7/1313 91/18639 0.0769230769230769 1.0919796121624 0.46180429375223 0.891725807034067 GO:0004407 histone deacetylase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0016881 acid-amino acid ligase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0032931 histone H3K56 acetyltransferase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0033558 protein lysine deacetylase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0043992 histone H3K9 acetyltransferase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0043993 histone H3K18 acetyltransferase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0043994 histone H3K23 acetyltransferase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0043999 histone H2AK5 acetyltransferase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0044012 histone H2AK9 acetyltransferase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0044014 histone H2BK5 acetyltransferase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0044015 histone H2BK12 acetyltransferase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0044016 histone H3K4 acetyltransferase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0044017 histone H3K27 acetyltransferase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0044018 histone H3K36 acetyltransferase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0046972 histone H4K16 acetyltransferase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0050321 tau-protein kinase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0140908 histone H3K122 acetyltransferase activity 2/1313 22/18639 0.0909090909090909 1.29052135982829 0.46538272754555 0.891725807034067 GO:0044390 ubiquitin-like protein conjugating enzyme binding 3/1313 36/18639 0.0833333333333333 1.18297791317593 0.470470841396226 0.891725807034067 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/1313 36/18639 0.0833333333333333 1.18297791317593 0.470470841396226 0.891725807034067 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/1313 36/18639 0.0833333333333333 1.18297791317593 0.470470841396226 0.891725807034067 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/1313 36/18639 0.0833333333333333 1.18297791317593 0.470470841396226 0.891725807034067 GO:0005126 cytokine receptor binding 20/1313 275/18639 0.0727272727272727 1.03241708786263 0.474678214559983 0.891725807034067 GO:0019888 protein phosphatase regulator activity 8/1313 107/18639 0.0747663551401869 1.06136336135411 0.483905531389406 0.891725807034067 GO:0046332 SMAD binding 6/1313 79/18639 0.0759493670886076 1.07815708542617 0.485889308511793 0.891725807034067 GO:0005048 signal sequence binding 4/1313 51/18639 0.0784313725490196 1.11339097710676 0.487972820828654 0.891725807034067 GO:0016597 amino acid binding 4/1313 51/18639 0.0784313725490196 1.11339097710676 0.487972820828654 0.891725807034067 GO:0030544 Hsp70 protein binding 4/1313 51/18639 0.0784313725490196 1.11339097710676 0.487972820828654 0.891725807034067 GO:0019213 deacetylase activity 3/1313 37/18639 0.0810810810810811 1.15100553714415 0.488866055752877 0.891725807034067 GO:0004602 glutathione peroxidase activity 2/1313 23/18639 0.0869565217391304 1.23441173548793 0.488943914457864 0.891725807034067 GO:0016849 phosphorus-oxygen lyase activity 2/1313 23/18639 0.0869565217391304 1.23441173548793 0.488943914457864 0.891725807034067 GO:0017134 fibroblast growth factor binding 2/1313 23/18639 0.0869565217391304 1.23441173548793 0.488943914457864 0.891725807034067 GO:0031681 G-protein beta-subunit binding 2/1313 23/18639 0.0869565217391304 1.23441173548793 0.488943914457864 0.891725807034067 GO:0044013 histone H2B acetyltransferase activity 2/1313 23/18639 0.0869565217391304 1.23441173548793 0.488943914457864 0.891725807034067 GO:0070577 lysine-acetylated histone binding 2/1313 23/18639 0.0869565217391304 1.23441173548793 0.488943914457864 0.891725807034067 GO:0044325 transmembrane transporter binding 10/1313 136/18639 0.0735294117647059 1.04380404103759 0.491583290421355 0.891725807034067 GO:0001217 DNA-binding transcription repressor activity 20/1313 278/18639 0.0719424460431655 1.02127589626699 0.494674360200364 0.891725807034067 GO:0008235 metalloexopeptidase activity 5/1313 66/18639 0.0757575757575758 1.07543446652358 0.500593387006786 0.891725807034067 GO:0005315 phosphate transmembrane transporter activity 2/1313 24/18639 0.0833333333333333 1.18297791317593 0.511841387327989 0.891725807034067 GO:0030215 semaphorin receptor binding 2/1313 24/18639 0.0833333333333333 1.18297791317593 0.511841387327989 0.891725807034067 GO:0035035 histone acetyltransferase binding 2/1313 24/18639 0.0833333333333333 1.18297791317593 0.511841387327989 0.891725807034067 GO:0043998 histone H2A acetyltransferase activity 2/1313 24/18639 0.0833333333333333 1.18297791317593 0.511841387327989 0.891725807034067 GO:0050699 WW domain binding 2/1313 24/18639 0.0833333333333333 1.18297791317593 0.511841387327989 0.891725807034067 GO:0070840 dynein complex binding 2/1313 24/18639 0.0833333333333333 1.18297791317593 0.511841387327989 0.891725807034067 GO:0140033 acetylation-dependent protein binding 2/1313 24/18639 0.0833333333333333 1.18297791317593 0.511841387327989 0.891725807034067 GO:0140612 DNA damage sensor activity 2/1313 24/18639 0.0833333333333333 1.18297791317593 0.511841387327989 0.891725807034067 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0004955 prostaglandin receptor activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0005031 tumor necrosis factor receptor activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0005131 growth hormone receptor binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0005528 FK506 binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0008140 cAMP response element binding protein binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0008190 eukaryotic initiation factor 4E binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0008401 retinoic acid 4-hydroxylase activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0015187 glycine transmembrane transporter activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0016427 tRNA (cytidine) methyltransferase activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0016868 intramolecular phosphotransferase activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0031419 cobalamin binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0032356 oxidized DNA binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0042975 peroxisome proliferator activated receptor binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0043121 neurotrophin binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0043295 glutathione binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0047429 nucleoside triphosphate diphosphatase activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0050308 sugar-phosphatase activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0070097 delta-catenin binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0099122 RNA polymerase II C-terminal domain binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:0140940 histone H2A methyltransferase activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:1990259 histone H2AQ104 methyltransferase activity 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:1990763 arrestin family protein binding 1/1313 10/18639 0.1 1.41957349581112 0.518409922037832 0.891725807034067 GO:1901505 carbohydrate derivative transmembrane transporter activity 4/1313 53/18639 0.0754716981132075 1.07137622325368 0.518586173216899 0.891725807034067 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 3/1313 39/18639 0.0769230769230769 1.0919796121624 0.524680324732821 0.892706217850806 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/1313 39/18639 0.0769230769230769 1.0919796121624 0.524680324732821 0.892706217850806 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/1313 39/18639 0.0769230769230769 1.0919796121624 0.524680324732821 0.892706217850806 GO:0003777 microtubule motor activity 5/1313 68/18639 0.0735294117647059 1.04380404103759 0.527473256010248 0.892706217850806 GO:1990841 promoter-specific chromatin binding 5/1313 68/18639 0.0735294117647059 1.04380404103759 0.527473256010248 0.892706217850806 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 4/1313 54/18639 0.0740740740740741 1.05153592282305 0.533565932333304 0.892706217850806 GO:0001848 complement binding 2/1313 25/18639 0.08 1.1356587966489 0.534051687326986 0.892706217850806 GO:0004709 MAP kinase kinase kinase activity 2/1313 25/18639 0.08 1.1356587966489 0.534051687326986 0.892706217850806 GO:0008139 nuclear localization sequence binding 2/1313 25/18639 0.08 1.1356587966489 0.534051687326986 0.892706217850806 GO:0008483 transaminase activity 2/1313 25/18639 0.08 1.1356587966489 0.534051687326986 0.892706217850806 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/1313 25/18639 0.08 1.1356587966489 0.534051687326986 0.892706217850806 GO:0120020 cholesterol transfer activity 2/1313 25/18639 0.08 1.1356587966489 0.534051687326986 0.892706217850806 GO:0004725 protein tyrosine phosphatase activity 7/1313 98/18639 0.0714285714285714 1.01398106843651 0.541155866290931 0.892706217850806 GO:0032451 demethylase activity 3/1313 40/18639 0.075 1.06468012185834 0.542059692176911 0.892706217850806 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/1313 40/18639 0.075 1.06468012185834 0.542059692176911 0.892706217850806 GO:0051117 ATPase binding 6/1313 84/18639 0.0714285714285714 1.01398106843651 0.546738637561482 0.892706217850806 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0003953 NAD+ nucleosidase activity 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0004016 adenylate cyclase activity 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0004954 prostanoid receptor activity 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0015217 ADP transmembrane transporter activity 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0019203 carbohydrate phosphatase activity 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0019206 nucleoside kinase activity 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0019864 IgG binding 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0032794 GTPase activating protein binding 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0050786 RAGE receptor binding 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0140537 transcription regulator activator activity 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:1900750 oligopeptide binding 1/1313 11/18639 0.0909090909090909 1.29052135982829 0.552353116646471 0.892706217850806 GO:0097110 scaffold protein binding 5/1313 70/18639 0.0714285714285714 1.01398106843651 0.553694634966011 0.892706217850806 GO:0004529 DNA exonuclease activity 2/1313 26/18639 0.0769230769230769 1.0919796121624 0.555557947225598 0.892706217850806 GO:0008143 poly(A) binding 2/1313 26/18639 0.0769230769230769 1.0919796121624 0.555557947225598 0.892706217850806 GO:0008198 ferrous iron binding 2/1313 26/18639 0.0769230769230769 1.0919796121624 0.555557947225598 0.892706217850806 GO:0043548 phosphatidylinositol 3-kinase binding 2/1313 26/18639 0.0769230769230769 1.0919796121624 0.555557947225598 0.892706217850806 GO:0050681 nuclear androgen receptor binding 2/1313 26/18639 0.0769230769230769 1.0919796121624 0.555557947225598 0.892706217850806 GO:0052742 phosphatidylinositol kinase activity 2/1313 26/18639 0.0769230769230769 1.0919796121624 0.555557947225598 0.892706217850806 GO:0070412 R-SMAD binding 2/1313 26/18639 0.0769230769230769 1.0919796121624 0.555557947225598 0.892706217850806 GO:0019212 phosphatase inhibitor activity 4/1313 56/18639 0.0714285714285714 1.01398106843651 0.562805688069023 0.895537024235745 GO:0016859 cis-trans isomerase activity 3/1313 42/18639 0.0714285714285714 1.01398106843651 0.575683609593148 0.895537024235745 GO:0019894 kinesin binding 3/1313 42/18639 0.0714285714285714 1.01398106843651 0.575683609593148 0.895537024235745 GO:0031492 nucleosomal DNA binding 3/1313 42/18639 0.0714285714285714 1.01398106843651 0.575683609593148 0.895537024235745 GO:0035198 miRNA binding 3/1313 42/18639 0.0714285714285714 1.01398106843651 0.575683609593148 0.895537024235745 GO:0004364 glutathione transferase activity 2/1313 27/18639 0.0740740740740741 1.05153592282305 0.57634908036461 0.895537024235745 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/1313 27/18639 0.0740740740740741 1.05153592282305 0.57634908036461 0.895537024235745 GO:0023026 MHC class II protein complex binding 2/1313 27/18639 0.0740740740740741 1.05153592282305 0.57634908036461 0.895537024235745 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/1313 27/18639 0.0740740740740741 1.05153592282305 0.57634908036461 0.895537024235745 GO:0042379 chemokine receptor binding 5/1313 72/18639 0.0694444444444444 0.985814927646611 0.579182110693562 0.895537024235745 GO:0003714 transcription corepressor activity 14/1313 204/18639 0.0686274509803922 0.974217104968416 0.580194374621158 0.895537024235745 GO:0000340 RNA 7-methylguanosine cap binding 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0003720 telomerase activity 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0004126 cytidine deaminase activity 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0005078 MAP-kinase scaffold activity 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0005436 sodium:phosphate symporter activity 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0005527 macrolide binding 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0008179 adenylate cyclase binding 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0017166 vinculin binding 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0031543 peptidyl-proline dioxygenase activity 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0034452 dynactin binding 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0035259 nuclear glucocorticoid receptor binding 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0035497 cAMP response element binding 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0036009 protein-glutamine N-methyltransferase activity 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0070008 serine-type exopeptidase activity 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0070410 co-SMAD binding 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0097371 MDM2/MDM4 family protein binding 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:1990459 transferrin receptor binding 1/1313 12/18639 0.0833333333333333 1.18297791317593 0.583905637466912 0.895537024235745 GO:0008238 exopeptidase activity 7/1313 102/18639 0.0686274509803922 0.974217104968416 0.584272699307204 0.895537024235745 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 4/1313 58/18639 0.0689655172413793 0.979016204007669 0.591013165914202 0.903201268140414 GO:0004521 RNA endonuclease activity 5/1313 73/18639 0.0684931506849315 0.97231061356926 0.591630455119463 0.903201268140414 GO:0008200 ion channel inhibitor activity 3/1313 43/18639 0.0697674418604651 0.990400113356595 0.591903743684252 0.903201268140414 GO:0016651 oxidoreductase activity, acting on NAD(P)H 6/1313 88/18639 0.0681818181818182 0.967891019871218 0.592986464867881 0.903399444958767 GO:0036408 histone H3K14 acetyltransferase activity 2/1313 28/18639 0.0714285714285714 1.01398106843651 0.596419051040739 0.903399444958767 GO:0050698 proteoglycan sulfotransferase activity 2/1313 28/18639 0.0714285714285714 1.01398106843651 0.596419051040739 0.903399444958767 GO:0051959 dynein light intermediate chain binding 2/1313 28/18639 0.0714285714285714 1.01398106843651 0.596419051040739 0.903399444958767 GO:0141052 histone H3 demethylase activity 2/1313 28/18639 0.0714285714285714 1.01398106843651 0.596419051040739 0.903399444958767 GO:0048029 monosaccharide binding 5/1313 74/18639 0.0675675675675676 0.959171280953459 0.603872599128582 0.910133741383064 GO:0045309 protein phosphorylated amino acid binding 4/1313 59/18639 0.0677966101694915 0.962422709024488 0.604707211128137 0.910133741383064 GO:0005319 lipid transporter activity 12/1313 178/18639 0.0674157303370786 0.957015839872665 0.605379248474815 0.910133741383064 GO:0016248 channel inhibitor activity 3/1313 44/18639 0.0681818181818182 0.967891019871218 0.607716734190536 0.910133741383064 GO:0016790 thiolester hydrolase activity 3/1313 44/18639 0.0681818181818182 0.967891019871218 0.607716734190536 0.910133741383064 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1313 13/18639 0.0769230769230769 1.0919796121624 0.613235744194026 0.910133741383064 GO:0003964 RNA-directed DNA polymerase activity 1/1313 13/18639 0.0769230769230769 1.0919796121624 0.613235744194026 0.910133741383064 GO:0005035 death receptor activity 1/1313 13/18639 0.0769230769230769 1.0919796121624 0.613235744194026 0.910133741383064 GO:0008035 high-density lipoprotein particle binding 1/1313 13/18639 0.0769230769230769 1.0919796121624 0.613235744194026 0.910133741383064 GO:0019104 DNA N-glycosylase activity 1/1313 13/18639 0.0769230769230769 1.0919796121624 0.613235744194026 0.910133741383064 GO:0019855 calcium channel inhibitor activity 1/1313 13/18639 0.0769230769230769 1.0919796121624 0.613235744194026 0.910133741383064 GO:0046975 histone H3K36 methyltransferase activity 1/1313 13/18639 0.0769230769230769 1.0919796121624 0.613235744194026 0.910133741383064 GO:0071837 HMG box domain binding 1/1313 13/18639 0.0769230769230769 1.0919796121624 0.613235744194026 0.910133741383064 GO:0140333 glycerophospholipid flippase activity 1/1313 13/18639 0.0769230769230769 1.0919796121624 0.613235744194026 0.910133741383064 GO:0016417 S-acyltransferase activity 2/1313 29/18639 0.0689655172413793 0.979016204007669 0.615766218875606 0.911263226209589 GO:0106222 lncRNA binding 2/1313 29/18639 0.0689655172413793 0.979016204007669 0.615766218875606 0.911263226209589 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 4/1313 60/18639 0.0666666666666667 0.946382330540746 0.618118407343828 0.913431792774954 GO:0046915 transition metal ion transmembrane transporter activity 3/1313 45/18639 0.0666666666666667 0.946382330540746 0.623115666058613 0.918181882747312 GO:0141110 transporter inhibitor activity 3/1313 45/18639 0.0666666666666667 0.946382330540746 0.623115666058613 0.918181882747312 GO:0008013 beta-catenin binding 7/1313 106/18639 0.0660377358490566 0.937454195346966 0.62530163745466 0.920086695111856 GO:0015399 primary active transmembrane transporter activity 11/1313 166/18639 0.0662650602409639 0.940681232163995 0.62753091684061 0.922049706627429 GO:0031210 phosphatidylcholine binding 2/1313 30/18639 0.0666666666666667 0.946382330540746 0.634392750377267 0.922678123625079 GO:0032452 histone demethylase activity 2/1313 30/18639 0.0666666666666667 0.946382330540746 0.634392750377267 0.922678123625079 GO:0043995 histone H4K5 acetyltransferase activity 2/1313 30/18639 0.0666666666666667 0.946382330540746 0.634392750377267 0.922678123625079 GO:0043996 histone H4K8 acetyltransferase activity 2/1313 30/18639 0.0666666666666667 0.946382330540746 0.634392750377267 0.922678123625079 GO:0043997 histone H4K12 acetyltransferase activity 2/1313 30/18639 0.0666666666666667 0.946382330540746 0.634392750377267 0.922678123625079 GO:0043178 alcohol binding 6/1313 92/18639 0.0652173913043478 0.925808801615947 0.636622870066461 0.922678123625079 GO:0005161 platelet-derived growth factor receptor binding 1/1313 14/18639 0.0714285714285714 1.01398106843651 0.640499862516438 0.922678123625079 GO:0005347 ATP transmembrane transporter activity 1/1313 14/18639 0.0714285714285714 1.01398106843651 0.640499862516438 0.922678123625079 GO:0008174 mRNA methyltransferase activity 1/1313 14/18639 0.0714285714285714 1.01398106843651 0.640499862516438 0.922678123625079 GO:0019763 immunoglobulin receptor activity 1/1313 14/18639 0.0714285714285714 1.01398106843651 0.640499862516438 0.922678123625079 GO:0032454 histone H3K9 demethylase activity 1/1313 14/18639 0.0714285714285714 1.01398106843651 0.640499862516438 0.922678123625079 GO:0071933 Arp2/3 complex binding 1/1313 14/18639 0.0714285714285714 1.01398106843651 0.640499862516438 0.922678123625079 GO:1901474 azole transmembrane transporter activity 1/1313 14/18639 0.0714285714285714 1.01398106843651 0.640499862516438 0.922678123625079 GO:1901612 cardiolipin binding 1/1313 14/18639 0.0714285714285714 1.01398106843651 0.640499862516438 0.922678123625079 GO:0004843 cysteine-type deubiquitinase activity 7/1313 108/18639 0.0648148148148148 0.92009393247017 0.644946119772486 0.927785619225783 GO:0005452 solute:inorganic anion antiporter activity 2/1313 31/18639 0.0645161290322581 0.915853868265238 0.652304091492285 0.933656047246226 GO:0072349 modified amino acid transmembrane transporter activity 2/1313 31/18639 0.0645161290322581 0.915853868265238 0.652304091492285 0.933656047246226 GO:0140457 protein demethylase activity 2/1313 31/18639 0.0645161290322581 0.915853868265238 0.652304091492285 0.933656047246226 GO:0061749 forked DNA-dependent helicase activity 3/1313 47/18639 0.0638297872340425 0.906110742007098 0.652652770890566 0.933656047246226 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/1313 15/18639 0.0666666666666667 0.946382330540746 0.665843415832729 0.934407260639474 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/1313 15/18639 0.0666666666666667 0.946382330540746 0.665843415832729 0.934407260639474 GO:0016846 carbon-sulfur lyase activity 1/1313 15/18639 0.0666666666666667 0.946382330540746 0.665843415832729 0.934407260639474 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/1313 15/18639 0.0666666666666667 0.946382330540746 0.665843415832729 0.934407260639474 GO:0017081 chloride channel regulator activity 1/1313 15/18639 0.0666666666666667 0.946382330540746 0.665843415832729 0.934407260639474 GO:0031386 protein tag activity 1/1313 15/18639 0.0666666666666667 0.946382330540746 0.665843415832729 0.934407260639474 GO:0033130 acetylcholine receptor binding 1/1313 15/18639 0.0666666666666667 0.946382330540746 0.665843415832729 0.934407260639474 GO:0034483 heparan sulfate sulfotransferase activity 1/1313 15/18639 0.0666666666666667 0.946382330540746 0.665843415832729 0.934407260639474 GO:0042809 nuclear vitamin D receptor binding 1/1313 15/18639 0.0666666666666667 0.946382330540746 0.665843415832729 0.934407260639474 GO:0050780 dopamine receptor binding 1/1313 15/18639 0.0666666666666667 0.946382330540746 0.665843415832729 0.934407260639474 GO:0141047 molecular tag activity 1/1313 15/18639 0.0666666666666667 0.946382330540746 0.665843415832729 0.934407260639474 GO:0141050 histone H3K deacetylase activity 1/1313 15/18639 0.0666666666666667 0.946382330540746 0.665843415832729 0.934407260639474 GO:0141051 histone H4K deacetylase activity 1/1313 15/18639 0.0666666666666667 0.946382330540746 0.665843415832729 0.934407260639474 GO:0009378 four-way junction helicase activity 3/1313 48/18639 0.0625 0.88723343488195 0.666785763660207 0.934407260639474 GO:0036121 double-stranded DNA helicase activity 3/1313 48/18639 0.0625 0.88723343488195 0.666785763660207 0.934407260639474 GO:0015106 bicarbonate transmembrane transporter activity 2/1313 32/18639 0.0625 0.88723343488195 0.669508495485658 0.934408875813316 GO:0022884 macromolecule transmembrane transporter activity 2/1313 32/18639 0.0625 0.88723343488195 0.669508495485658 0.934408875813316 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/1313 32/18639 0.0625 0.88723343488195 0.669508495485658 0.934408875813316 GO:0035254 glutamate receptor binding 3/1313 49/18639 0.0612244897959184 0.86912663008844 0.680494065604467 0.945517505341159 GO:0120013 lipid transfer activity 4/1313 65/18639 0.0615384615384615 0.87358368972992 0.68075890260592 0.945517505341159 GO:0160215 deacylase activity 4/1313 65/18639 0.0615384615384615 0.87358368972992 0.68075890260592 0.945517505341159 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/1313 33/18639 0.0606060606060606 0.86034757321886 0.686016600980156 0.945517505341159 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/1313 16/18639 0.0625 0.88723343488195 0.689401598554573 0.945517505341159 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/1313 16/18639 0.0625 0.88723343488195 0.689401598554573 0.945517505341159 GO:0005149 interleukin-1 receptor binding 1/1313 16/18639 0.0625 0.88723343488195 0.689401598554573 0.945517505341159 GO:0022858 alanine transmembrane transporter activity 1/1313 16/18639 0.0625 0.88723343488195 0.689401598554573 0.945517505341159 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1313 16/18639 0.0625 0.88723343488195 0.689401598554573 0.945517505341159 GO:0055102 lipase inhibitor activity 1/1313 16/18639 0.0625 0.88723343488195 0.689401598554573 0.945517505341159 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/1313 16/18639 0.0625 0.88723343488195 0.689401598554573 0.945517505341159 GO:0070411 I-SMAD binding 1/1313 16/18639 0.0625 0.88723343488195 0.689401598554573 0.945517505341159 GO:0140328 floppase activity 1/1313 16/18639 0.0625 0.88723343488195 0.689401598554573 0.945517505341159 GO:0048020 CCR chemokine receptor binding 3/1313 50/18639 0.06 0.851744097486672 0.693778596777992 0.950245263228611 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/1313 34/18639 0.0588235294117647 0.83504323283007 0.701841055439408 0.950245263228611 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 2/1313 34/18639 0.0588235294117647 0.83504323283007 0.701841055439408 0.950245263228611 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0008569 minus-end-directed microtubule motor activity 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0015278 intracellularly gated calcium channel activity 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0016018 cyclosporin A binding 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0016805 dipeptidase activity 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0030548 acetylcholine receptor regulator activity 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0031489 myosin V binding 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0032183 SUMO binding 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0032977 membrane insertase activity 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0038191 neuropilin binding 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0045125 bioactive lipid receptor activity 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0045236 CXCR chemokine receptor binding 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0048038 quinone binding 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0070403 NAD+ binding 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:1990226 histone methyltransferase binding 1/1313 17/18639 0.0588235294117647 0.83504323283007 0.711300095096368 0.950245263228611 GO:0016229 steroid dehydrogenase activity 2/1313 35/18639 0.0571428571428571 0.811184854749211 0.716996179793764 0.956614074077172 GO:0051015 actin filament binding 13/1313 209/18639 0.062200956937799 0.882988298829883 0.718850685022247 0.957567243728451 GO:1990782 protein tyrosine kinase binding 7/1313 117/18639 0.0598290598290598 0.849317476126311 0.725475939189227 0.957567243728451 GO:0004864 protein phosphatase inhibitor activity 3/1313 53/18639 0.0566037735849057 0.803532167440256 0.731115793779887 0.957567243728451 GO:0005246 calcium channel regulator activity 3/1313 53/18639 0.0566037735849057 0.803532167440256 0.731115793779887 0.957567243728451 GO:0016409 palmitoyltransferase activity 2/1313 36/18639 0.0555555555555556 0.788651942117289 0.731497670287737 0.957567243728451 GO:0045505 dynein intermediate chain binding 2/1313 36/18639 0.0555555555555556 0.788651942117289 0.731497670287737 0.957567243728451 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/1313 18/18639 0.0555555555555556 0.788651942117289 0.731655748363389 0.957567243728451 GO:0008308 voltage-gated monoatomic anion channel activity 1/1313 18/18639 0.0555555555555556 0.788651942117289 0.731655748363389 0.957567243728451 GO:0008525 phosphatidylcholine transporter activity 1/1313 18/18639 0.0555555555555556 0.788651942117289 0.731655748363389 0.957567243728451 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/1313 18/18639 0.0555555555555556 0.788651942117289 0.731655748363389 0.957567243728451 GO:0034185 apolipoprotein binding 1/1313 18/18639 0.0555555555555556 0.788651942117289 0.731655748363389 0.957567243728451 GO:0070064 proline-rich region binding 1/1313 18/18639 0.0555555555555556 0.788651942117289 0.731655748363389 0.957567243728451 GO:0070628 proteasome binding 1/1313 18/18639 0.0555555555555556 0.788651942117289 0.731655748363389 0.957567243728451 GO:0099602 neurotransmitter receptor regulator activity 1/1313 18/18639 0.0555555555555556 0.788651942117289 0.731655748363389 0.957567243728451 GO:1901611 phosphatidylglycerol binding 1/1313 18/18639 0.0555555555555556 0.788651942117289 0.731655748363389 0.957567243728451 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 11/1313 181/18639 0.0607734806629834 0.862724223973609 0.73661844482955 0.962838830170605 GO:0015485 cholesterol binding 3/1313 54/18639 0.0555555555555556 0.788651942117289 0.74273637386498 0.968790096142412 GO:0030280 structural constituent of skin epidermis 2/1313 37/18639 0.0540540540540541 0.767337024762767 0.745362333975443 0.968790096142412 GO:0140299 molecular sensor activity 4/1313 71/18639 0.0563380281690141 0.799759715949927 0.745941425957403 0.968790096142412 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/1313 19/18639 0.0526315789473684 0.747143945163747 0.75057718128315 0.968790096142412 GO:0005520 insulin-like growth factor binding 1/1313 19/18639 0.0526315789473684 0.747143945163747 0.75057718128315 0.968790096142412 GO:0031420 alkali metal ion binding 1/1313 19/18639 0.0526315789473684 0.747143945163747 0.75057718128315 0.968790096142412 GO:0034987 immunoglobulin receptor binding 1/1313 19/18639 0.0526315789473684 0.747143945163747 0.75057718128315 0.968790096142412 GO:0046624 sphingolipid transporter activity 1/1313 19/18639 0.0526315789473684 0.747143945163747 0.75057718128315 0.968790096142412 GO:0050145 nucleoside monophosphate kinase activity 1/1313 19/18639 0.0526315789473684 0.747143945163747 0.75057718128315 0.968790096142412 GO:0097001 ceramide binding 1/1313 19/18639 0.0526315789473684 0.747143945163747 0.75057718128315 0.968790096142412 GO:0003779 actin binding 28/1313 443/18639 0.0632054176072235 0.897247356268879 0.752768573555886 0.970402541630241 GO:0000146 microfilament motor activity 2/1313 38/18639 0.0526315789473684 0.747143945163747 0.758607854608667 0.974271932976219 GO:0005501 retinoid binding 2/1313 38/18639 0.0526315789473684 0.747143945163747 0.758607854608667 0.974271932976219 GO:0019840 isoprenoid binding 2/1313 38/18639 0.0526315789473684 0.747143945163747 0.758607854608667 0.974271932976219 GO:1901981 phosphatidylinositol phosphate binding 11/1313 185/18639 0.0594594594594595 0.844070727239044 0.761791099363603 0.977141758835008 GO:0030170 pyridoxal phosphate binding 3/1313 56/18639 0.0535714285714286 0.760485801327385 0.764772972185918 0.979220712767698 GO:0004497 monooxygenase activity 6/1313 106/18639 0.0566037735849057 0.803532167440256 0.765649443391548 0.979220712767698 GO:0000339 RNA cap binding 1/1313 20/18639 0.05 0.70978674790556 0.768165374676019 0.979220712767698 GO:0016505 peptidase activator activity involved in apoptotic process 1/1313 20/18639 0.05 0.70978674790556 0.768165374676019 0.979220712767698 GO:0031418 L-ascorbic acid binding 1/1313 20/18639 0.05 0.70978674790556 0.768165374676019 0.979220712767698 GO:0070279 vitamin B6 binding 3/1313 57/18639 0.0526315789473684 0.747143945163747 0.775202399615263 0.986969680597924 GO:0050997 quaternary ammonium group binding 2/1313 40/18639 0.05 0.70978674790556 0.783315369836276 0.992106588186427 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/1313 21/18639 0.0476190476190476 0.675987378957676 0.784514204529953 0.992106588186427 GO:0008373 sialyltransferase activity 1/1313 21/18639 0.0476190476190476 0.675987378957676 0.784514204529953 0.992106588186427 GO:0015174 basic amino acid transmembrane transporter activity 1/1313 21/18639 0.0476190476190476 0.675987378957676 0.784514204529953 0.992106588186427 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/1313 21/18639 0.0476190476190476 0.675987378957676 0.784514204529953 0.992106588186427 GO:0052689 carboxylic ester hydrolase activity 5/1313 92/18639 0.0543478260869565 0.771507334679956 0.785016378031008 0.992106588186427 GO:0051213 dioxygenase activity 5/1313 93/18639 0.0537634408602151 0.763211556887699 0.792853211737883 0.996068856850131 GO:0001530 lipopolysaccharide binding 2/1313 41/18639 0.0487804878048781 0.692474876005424 0.794815376468491 0.996068856850131 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/1313 41/18639 0.0487804878048781 0.692474876005424 0.794815376468491 0.996068856850131 GO:0017080 sodium channel regulator activity 2/1313 41/18639 0.0487804878048781 0.692474876005424 0.794815376468491 0.996068856850131 GO:0140318 protein transporter activity 2/1313 41/18639 0.0487804878048781 0.692474876005424 0.794815376468491 0.996068856850131 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/1313 59/18639 0.0508474576271186 0.721817031768366 0.794920971194959 0.996068856850131 GO:0070888 E-box binding 3/1313 59/18639 0.0508474576271186 0.721817031768366 0.794920971194959 0.996068856850131 GO:0008649 rRNA methyltransferase activity 1/1313 22/18639 0.0454545454545455 0.645260679914145 0.79971094152921 0.998426993666771 GO:0008970 phospholipase A1 activity 1/1313 22/18639 0.0454545454545455 0.645260679914145 0.79971094152921 0.998426993666771 GO:0033691 sialic acid binding 1/1313 22/18639 0.0454545454545455 0.645260679914145 0.79971094152921 0.998426993666771 GO:0042056 chemoattractant activity 2/1313 42/18639 0.0476190476190476 0.675987378957676 0.805771964812258 0.999999998407408 GO:0005200 structural constituent of cytoskeleton 6/1313 112/18639 0.0535714285714286 0.760485801327385 0.809276615258703 0.999999998407408 GO:0015026 coreceptor activity 3/1313 61/18639 0.0491803278688525 0.698150899579239 0.813173897354909 0.999999998407408 GO:0000295 adenine nucleotide transmembrane transporter activity 1/1313 23/18639 0.0434782608695652 0.617205867743965 0.813836715486998 0.999999998407408 GO:0005158 insulin receptor binding 1/1313 23/18639 0.0434782608695652 0.617205867743965 0.813836715486998 0.999999998407408 GO:0005212 structural constituent of eye lens 1/1313 23/18639 0.0434782608695652 0.617205867743965 0.813836715486998 0.999999998407408 GO:0042171 lysophosphatidic acid acyltransferase activity 1/1313 23/18639 0.0434782608695652 0.617205867743965 0.813836715486998 0.999999998407408 GO:0071617 lysophospholipid acyltransferase activity 1/1313 23/18639 0.0434782608695652 0.617205867743965 0.813836715486998 0.999999998407408 GO:0140102 catalytic activity, acting on a rRNA 1/1313 23/18639 0.0434782608695652 0.617205867743965 0.813836715486998 0.999999998407408 GO:0033293 monocarboxylic acid binding 4/1313 79/18639 0.0506329113924051 0.718771390284111 0.816364933876154 0.999999998407408 GO:0004857 enzyme inhibitor activity 25/1313 416/18639 0.0600961538461538 0.853109072001875 0.823336547748294 0.999999998407408 GO:0004806 triacylglycerol lipase activity 1/1313 24/18639 0.0416666666666667 0.591488956587967 0.826966947146086 0.999999998407408 GO:0005540 hyaluronic acid binding 1/1313 24/18639 0.0416666666666667 0.591488956587967 0.826966947146086 0.999999998407408 GO:0015295 solute:proton symporter activity 1/1313 24/18639 0.0416666666666667 0.591488956587967 0.826966947146086 0.999999998407408 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/1313 24/18639 0.0416666666666667 0.591488956587967 0.826966947146086 0.999999998407408 GO:0030552 cAMP binding 1/1313 24/18639 0.0416666666666667 0.591488956587967 0.826966947146086 0.999999998407408 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/1313 24/18639 0.0416666666666667 0.591488956587967 0.826966947146086 0.999999998407408 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/1313 24/18639 0.0416666666666667 0.591488956587967 0.826966947146086 0.999999998407408 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/1313 24/18639 0.0416666666666667 0.591488956587967 0.826966947146086 0.999999998407408 GO:0070300 phosphatidic acid binding 1/1313 24/18639 0.0416666666666667 0.591488956587967 0.826966947146086 0.999999998407408 GO:0042626 ATPase-coupled transmembrane transporter activity 5/1313 98/18639 0.0510204081632653 0.724272191740367 0.82871856115278 0.999999998407408 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 7/1313 132/18639 0.053030303030303 0.752804126566503 0.829850213141391 0.999999998407408 GO:0005507 copper ion binding 3/1313 63/18639 0.0476190476190476 0.675987378957676 0.830031009147513 0.999999998407408 GO:0001618 virus receptor activity 4/1313 81/18639 0.0493827160493827 0.701023948548701 0.831227758028811 0.999999998407408 GO:0015101 organic cation transmembrane transporter activity 4/1313 81/18639 0.0493827160493827 0.701023948548701 0.831227758028811 0.999999998407408 GO:0140272 exogenous protein binding 4/1313 82/18639 0.0487804878048781 0.692474876005424 0.838275422286354 0.999999998407408 GO:0003707 nuclear steroid receptor activity 1/1313 25/18639 0.04 0.567829398324448 0.839171749638548 0.999999998407408 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/1313 25/18639 0.04 0.567829398324448 0.839171749638548 0.999999998407408 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/1313 25/18639 0.04 0.567829398324448 0.839171749638548 0.999999998407408 GO:0019707 protein-cysteine S-acyltransferase activity 1/1313 25/18639 0.04 0.567829398324448 0.839171749638548 0.999999998407408 GO:0047617 fatty acyl-CoA hydrolase activity 1/1313 25/18639 0.04 0.567829398324448 0.839171749638548 0.999999998407408 GO:0004180 carboxypeptidase activity 2/1313 46/18639 0.0434782608695652 0.617205867743965 0.844551549974137 0.999999998407408 GO:0030276 clathrin binding 2/1313 46/18639 0.0434782608695652 0.617205867743965 0.844551549974137 0.999999998407408 GO:0030165 PDZ domain binding 4/1313 83/18639 0.0481927710843374 0.684131805210178 0.845074702557512 0.999999998407408 GO:0004435 phosphatidylinositol phospholipase C activity 1/1313 26/18639 0.0384615384615385 0.5459898060812 0.850516301735066 0.999999998407408 GO:0005227 calcium-activated cation channel activity 1/1313 26/18639 0.0384615384615385 0.5459898060812 0.850516301735066 0.999999998407408 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/1313 26/18639 0.0384615384615385 0.5459898060812 0.850516301735066 0.999999998407408 GO:0015216 purine nucleotide transmembrane transporter activity 1/1313 26/18639 0.0384615384615385 0.5459898060812 0.850516301735066 0.999999998407408 GO:0016289 acyl-CoA hydrolase activity 1/1313 26/18639 0.0384615384615385 0.5459898060812 0.850516301735066 0.999999998407408 GO:0019865 immunoglobulin binding 1/1313 26/18639 0.0384615384615385 0.5459898060812 0.850516301735066 0.999999998407408 GO:0030507 spectrin binding 1/1313 26/18639 0.0384615384615385 0.5459898060812 0.850516301735066 0.999999998407408 GO:0050750 low-density lipoprotein particle receptor binding 1/1313 26/18639 0.0384615384615385 0.5459898060812 0.850516301735066 0.999999998407408 GO:0120014 phospholipid transfer activity 1/1313 26/18639 0.0384615384615385 0.5459898060812 0.850516301735066 0.999999998407408 GO:0005504 fatty acid binding 2/1313 47/18639 0.0425531914893617 0.604073828004732 0.853080384600073 0.999999998407408 GO:0031406 carboxylic acid binding 10/1313 187/18639 0.053475935828877 0.7591302116637 0.856043795656774 0.999999998407408 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/1313 67/18639 0.0447761194029851 0.635629923497516 0.859851539543391 0.999999998407408 GO:0005385 zinc ion transmembrane transporter activity 1/1313 27/18639 0.037037037037037 0.525767961411526 0.861061194864699 0.999999998407408 GO:0008266 poly(U) RNA binding 1/1313 27/18639 0.037037037037037 0.525767961411526 0.861061194864699 0.999999998407408 GO:0008320 protein transmembrane transporter activity 1/1313 27/18639 0.037037037037037 0.525767961411526 0.861061194864699 0.999999998407408 GO:0015252 proton channel activity 1/1313 27/18639 0.037037037037037 0.525767961411526 0.861061194864699 0.999999998407408 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/1313 27/18639 0.037037037037037 0.525767961411526 0.861061194864699 0.999999998407408 GO:0035255 ionotropic glutamate receptor binding 1/1313 27/18639 0.037037037037037 0.525767961411526 0.861061194864699 0.999999998407408 GO:0032266 phosphatidylinositol-3-phosphate binding 2/1313 48/18639 0.0416666666666667 0.591488956587967 0.861180150727894 0.999999998407408 GO:0038187 pattern recognition receptor activity 2/1313 48/18639 0.0416666666666667 0.591488956587967 0.861180150727894 0.999999998407408 GO:0043177 organic acid binding 10/1313 189/18639 0.0529100529100529 0.751097087730751 0.864536117391062 0.999999998407408 GO:0140375 immune receptor activity 8/1313 156/18639 0.0512820512820513 0.727986408108266 0.866498104404872 0.999999998407408 GO:0032934 sterol binding 3/1313 68/18639 0.0441176470588235 0.626282424622553 0.866550121331484 0.999999998407408 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6/1313 122/18639 0.0491803278688525 0.698150899579239 0.867545002033185 0.999999998407408 GO:0005516 calmodulin binding 11/1313 207/18639 0.0531400966183575 0.754362727242624 0.870346174875957 0.999999998407408 GO:0045499 chemorepellent activity 1/1313 28/18639 0.0357142857142857 0.506990534218257 0.870862755747068 0.999999998407408 GO:0046625 sphingolipid binding 1/1313 28/18639 0.0357142857142857 0.506990534218257 0.870862755747068 0.999999998407408 GO:0046875 ephrin receptor binding 1/1313 28/18639 0.0357142857142857 0.506990534218257 0.870862755747068 0.999999998407408 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/1313 28/18639 0.0357142857142857 0.506990534218257 0.870862755747068 0.999999998407408 GO:0005543 phospholipid binding 29/1313 497/18639 0.0583501006036217 0.828322562948138 0.878329036302561 0.999999998407408 GO:0004629 phospholipase C activity 1/1313 29/18639 0.0344827586206897 0.489508102003834 0.87997334634962 0.999999998407408 GO:0051861 glycolipid binding 1/1313 29/18639 0.0344827586206897 0.489508102003834 0.87997334634962 0.999999998407408 GO:0099604 ligand-gated calcium channel activity 1/1313 29/18639 0.0344827586206897 0.489508102003834 0.87997334634962 0.999999998407408 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/1313 30/18639 0.0333333333333333 0.473191165270373 0.88844164276246 0.999999998407408 GO:0008187 poly-pyrimidine tract binding 1/1313 30/18639 0.0333333333333333 0.473191165270373 0.88844164276246 0.999999998407408 GO:0022839 monoatomic ion-gated channel activity 1/1313 30/18639 0.0333333333333333 0.473191165270373 0.88844164276246 0.999999998407408 GO:0033612 receptor serine/threonine kinase binding 1/1313 30/18639 0.0333333333333333 0.473191165270373 0.88844164276246 0.999999998407408 GO:0048019 receptor antagonist activity 1/1313 30/18639 0.0333333333333333 0.473191165270373 0.88844164276246 0.999999998407408 GO:0030159 signaling receptor complex adaptor activity 2/1313 52/18639 0.0384615384615385 0.5459898060812 0.889643565674287 0.999999998407408 GO:0042826 histone deacetylase binding 6/1313 127/18639 0.047244094488189 0.670664643690293 0.89062453674255 0.999999998407408 GO:0008146 sulfotransferase activity 2/1313 53/18639 0.0377358490566038 0.535688111626838 0.895860341042695 0.999999998407408 GO:0016411 acylglycerol O-acyltransferase activity 1/1313 31/18639 0.032258064516129 0.457926934132619 0.896312894471466 0.999999998407408 GO:0047499 calcium-independent phospholipase A2 activity 1/1313 31/18639 0.032258064516129 0.457926934132619 0.896312894471466 0.999999998407408 GO:0070325 lipoprotein particle receptor binding 1/1313 31/18639 0.032258064516129 0.457926934132619 0.896312894471466 0.999999998407408 GO:0047498 calcium-dependent phospholipase A2 activity 1/1313 32/18639 0.03125 0.443616717440975 0.903629165406492 0.999999998407408 GO:0071813 lipoprotein particle binding 1/1313 32/18639 0.03125 0.443616717440975 0.903629165406492 0.999999998407408 GO:0071814 protein-lipid complex binding 1/1313 32/18639 0.03125 0.443616717440975 0.903629165406492 0.999999998407408 GO:0008237 metallopeptidase activity 9/1313 184/18639 0.0489130434782609 0.694356601211961 0.907811397242132 0.999999998407408 GO:0019239 deaminase activity 1/1313 33/18639 0.0303030303030303 0.43017378660943 0.910429558044815 0.999999998407408 GO:0170055 lipid transmembrane transporter activity 2/1313 56/18639 0.0357142857142857 0.506990534218257 0.912606724984933 0.999999998407408 GO:0019825 oxygen binding 1/1313 34/18639 0.0294117647058824 0.417521616415035 0.91675042176013 0.999999998407408 GO:0051427 hormone receptor binding 1/1313 34/18639 0.0294117647058824 0.417521616415035 0.91675042176013 0.999999998407408 GO:0090482 vitamin transmembrane transporter activity 1/1313 34/18639 0.0294117647058824 0.417521616415035 0.91675042176013 0.999999998407408 GO:0046906 tetrapyrrole binding 7/1313 152/18639 0.0460526315789474 0.653750952018279 0.91726203170528 0.999999998407408 GO:0004601 peroxidase activity 2/1313 57/18639 0.0350877192982456 0.498095963442498 0.917603245907466 0.999999998407408 GO:0004623 phospholipase A2 activity 1/1313 35/18639 0.0285714285714286 0.405592427374606 0.922625546523847 0.999999998407408 GO:0048306 calcium-dependent protein binding 3/1313 80/18639 0.0375 0.53234006092917 0.927370092933503 0.999999998407408 GO:0004190 aspartic-type endopeptidase activity 1/1313 36/18639 0.0277777777777778 0.394325971058644 0.928086342987736 0.999999998407408 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/1313 36/18639 0.0277777777777778 0.394325971058644 0.928086342987736 0.999999998407408 GO:0030971 receptor tyrosine kinase binding 3/1313 81/18639 0.037037037037037 0.525767961411526 0.931067875045221 0.999999998407408 GO:0022829 wide pore channel activity 1/1313 37/18639 0.027027027027027 0.383668512381384 0.933162009904744 0.999999998407408 GO:0030551 cyclic nucleotide binding 1/1313 37/18639 0.027027027027027 0.383668512381384 0.933162009904744 0.999999998407408 GO:0070001 aspartic-type peptidase activity 1/1313 37/18639 0.027027027027027 0.383668512381384 0.933162009904744 0.999999998407408 GO:0005109 frizzled binding 1/1313 38/18639 0.0263157894736842 0.373571972581874 0.937879689777611 0.999999998407408 GO:0043531 ADP binding 1/1313 38/18639 0.0263157894736842 0.373571972581874 0.937879689777611 0.999999998407408 GO:0015179 L-amino acid transmembrane transporter activity 2/1313 62/18639 0.032258064516129 0.457926934132619 0.938797412049533 0.999999998407408 GO:0099106 ion channel regulator activity 7/1313 160/18639 0.04375 0.621063404417365 0.939402554209985 0.999999998407408 GO:0020037 heme binding 6/1313 142/18639 0.0422535211267606 0.599819786962445 0.940394397160347 0.999999998407408 GO:0042277 peptide binding 12/1313 249/18639 0.0481927710843374 0.684131805210178 0.940772780580344 0.999999998407408 GO:1901682 sulfur compound transmembrane transporter activity 2/1313 63/18639 0.0317460317460317 0.450658252638451 0.942363523620091 0.999999998407408 GO:0008514 organic anion transmembrane transporter activity 13/1313 269/18639 0.0483271375464684 0.68603923589385 0.945848416751251 0.999999998407408 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3/1313 86/18639 0.0348837209302326 0.495200056678297 0.947086113520106 0.999999998407408 GO:0016209 antioxidant activity 3/1313 86/18639 0.0348837209302326 0.495200056678297 0.947086113520106 0.999999998407408 GO:0038024 cargo receptor activity 2/1313 65/18639 0.0307692307692308 0.43679184486496 0.948911291784247 0.999999998407408 GO:0004812 aminoacyl-tRNA ligase activity 1/1313 41/18639 0.024390243902439 0.346237438002712 0.950128356664665 0.999999998407408 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1313 41/18639 0.024390243902439 0.346237438002712 0.950128356664665 0.999999998407408 GO:0015078 proton transmembrane transporter activity 8/1313 185/18639 0.0432432432432432 0.613869619810214 0.953532573946108 0.999999998407408 GO:0016247 channel regulator activity 7/1313 168/18639 0.0416666666666667 0.591488956587967 0.95613419237885 0.999999998407408 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 5/1313 130/18639 0.0384615384615385 0.5459898060812 0.956240790164082 0.999999998407408 GO:0005245 voltage-gated calcium channel activity 1/1313 43/18639 0.0232558139534884 0.330133371118865 0.956921736730488 0.999999998407408 GO:0019842 vitamin binding 6/1313 150/18639 0.04 0.567829398324448 0.957651132619443 0.999999998407408 GO:1902936 phosphatidylinositol bisphosphate binding 4/1313 111/18639 0.036036036036036 0.511558016508512 0.957982750863201 0.999999998407408 GO:0141108 transporter regulator activity 7/1313 170/18639 0.0411764705882353 0.584530262981049 0.95960806365404 0.999999998407408 GO:0030547 signaling receptor inhibitor activity 1/1313 44/18639 0.0227272727272727 0.322630339957073 0.959963345661057 0.999999998407408 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/1313 70/18639 0.0285714285714286 0.405592427374606 0.962316616661157 0.999999998407408 GO:0042605 peptide antigen binding 1/1313 45/18639 0.0222222222222222 0.315460776846915 0.962790349003194 0.999999998407408 GO:0046982 protein heterodimerization activity 18/1313 369/18639 0.0487804878048781 0.692474876005424 0.965276751865805 0.999999998407408 GO:0015297 antiporter activity 5/1313 135/18639 0.037037037037037 0.525767961411526 0.965314597309306 0.999999998407408 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/1313 46/18639 0.0217391304347826 0.308602933871983 0.965417877870506 0.999999998407408 GO:0005518 collagen binding 2/1313 72/18639 0.0277777777777778 0.394325971058644 0.966671394623399 0.999999998407408 GO:0019838 growth factor binding 5/1313 136/18639 0.0367647058823529 0.521902020518794 0.96690721184387 0.999999998407408 GO:0015294 solute:monoatomic cation symporter activity 4/1313 116/18639 0.0344827586206897 0.489508102003834 0.967288989343516 0.999999998407408 GO:0043495 protein-membrane adaptor activity 1/1313 47/18639 0.0212765957446809 0.302036914002366 0.967859997289429 0.999999998407408 GO:0140359 ABC-type transporter activity 1/1313 47/18639 0.0212765957446809 0.302036914002366 0.967859997289429 0.999999998407408 GO:0005178 integrin binding 6/1313 161/18639 0.0372670807453416 0.529033600923399 0.974007466197952 0.999999998407408 GO:0005010 insulin-like growth factor receptor activity 1/1313 51/18639 0.0196078431372549 0.27834774427669 0.976022426374369 0.999999998407408 GO:0005030 neurotrophin receptor activity 1/1313 51/18639 0.0196078431372549 0.27834774427669 0.976022426374369 0.999999998407408 GO:0019955 cytokine binding 5/1313 144/18639 0.0347222222222222 0.492907463823305 0.977414619514676 0.999999998407408 GO:0005080 protein kinase C binding 1/1313 52/18639 0.0192307692307692 0.2729949030406 0.977716129525351 0.999999998407408 GO:0061135 endopeptidase regulator activity 7/1313 184/18639 0.0380434782608696 0.540055134275969 0.977732352586152 0.999999998407408 GO:0015171 amino acid transmembrane transporter activity 3/1313 102/18639 0.0294117647058824 0.417521616415035 0.977997027140795 0.999999998407408 GO:0015370 solute:sodium symporter activity 2/1313 79/18639 0.0253164556962025 0.359385695142056 0.978408582449984 0.999999998407408 GO:0001664 G protein-coupled receptor binding 13/1313 297/18639 0.0437710437710438 0.621362136213621 0.979009090645859 0.999999998407408 GO:0005544 calcium-dependent phospholipid binding 1/1313 53/18639 0.0188679245283019 0.267844055813419 0.979290279303864 0.999999998407408 GO:0003730 mRNA 3'-UTR binding 11/1313 262/18639 0.0419847328244275 0.596004139462684 0.980027880595392 0.999999998407408 GO:0015085 calcium ion transmembrane transporter activity 5/1313 147/18639 0.0340136054421769 0.482848127826911 0.980480203472082 0.999999998407408 GO:0061134 peptidase regulator activity 9/1313 226/18639 0.0398230088495575 0.565316878862835 0.980981371251628 0.999999998407408 GO:0008374 O-acyltransferase activity 1/1313 55/18639 0.0181818181818182 0.258104271965658 0.982113056059208 0.999999998407408 GO:0033218 amide binding 10/1313 247/18639 0.0404858299595142 0.574726111664421 0.982587384905609 0.999999998407408 GO:0001540 amyloid-beta binding 2/1313 83/18639 0.0240963855421687 0.342065902605089 0.98319817608291 0.999999998407408 GO:0016298 lipase activity 4/1313 130/18639 0.0307692307692308 0.43679184486496 0.984128295412329 0.999999998407408 GO:0005496 steroid binding 3/1313 108/18639 0.0277777777777778 0.394325971058644 0.984331862369718 0.999999998407408 GO:0004620 phospholipase activity 3/1313 109/18639 0.0275229357798165 0.390708301599391 0.985201165556498 0.999999998407408 GO:0001786 phosphatidylserine binding 1/1313 59/18639 0.0169491525423729 0.240605677256122 0.986657456286008 0.999999998407408 GO:0004879 nuclear receptor activity 1/1313 59/18639 0.0169491525423729 0.240605677256122 0.986657456286008 0.999999998407408 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/1313 60/18639 0.0166666666666667 0.236595582635187 0.987600338949973 0.999999998407408 GO:0098531 ligand-modulated transcription factor activity 1/1313 60/18639 0.0166666666666667 0.236595582635187 0.987600338949973 0.999999998407408 GO:1901681 sulfur compound binding 11/1313 275/18639 0.04 0.567829398324448 0.987917326183321 0.999999998407408 GO:0004175 endopeptidase activity 18/1313 405/18639 0.0444444444444444 0.630921553693831 0.988952742449443 0.999999998407408 GO:0072341 modified amino acid binding 2/1313 91/18639 0.021978021978022 0.311994174903543 0.989878936895249 0.999999998407408 GO:0008083 growth factor activity 5/1313 162/18639 0.0308641975308642 0.438139967842938 0.990768715933271 0.999999998407408 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 22/1313 484/18639 0.0454545454545455 0.645260679914145 0.991594923811679 0.999999998407408 GO:0042562 hormone binding 2/1313 94/18639 0.0212765957446809 0.302036914002366 0.991644637787235 0.999999998407408 GO:0046943 carboxylic acid transmembrane transporter activity 6/1313 188/18639 0.0319148936170213 0.453055371003549 0.99273434935219 0.999999998407408 GO:0008528 G protein-coupled peptide receptor activity 3/1313 122/18639 0.0245901639344262 0.34907544978962 0.993034357884026 0.999999998407408 GO:0005342 organic acid transmembrane transporter activity 6/1313 189/18639 0.0317460317460317 0.450658252638451 0.993082138375085 0.999999998407408 GO:0015293 symporter activity 4/1313 146/18639 0.0273972602739726 0.388924245427704 0.993289127424332 0.999999998407408 GO:0001216 DNA-binding transcription activator activity 22/1313 491/18639 0.044806517311609 0.636061444151622 0.993295196971816 0.999999998407408 GO:0001653 peptide receptor activity 3/1313 128/18639 0.0234375 0.332712538080731 0.995112687475287 0.999999998407408 GO:0005253 monoatomic anion channel activity 2/1313 103/18639 0.0194174757281553 0.27564533899245 0.995321390313989 0.999999998407408 GO:0005262 calcium channel activity 3/1313 131/18639 0.0229007633587786 0.325093166979646 0.995911947804324 0.999999998407408 GO:0017022 myosin binding 1/1313 76/18639 0.0131578947368421 0.186785986290937 0.996163750829358 0.999999998407408 GO:0098631 cell adhesion mediator activity 1/1313 76/18639 0.0131578947368421 0.186785986290937 0.996163750829358 0.999999998407408 GO:0022804 active transmembrane transporter activity 19/1313 457/18639 0.0415754923413567 0.590194670030881 0.996607983383563 0.999999998407408 GO:0019199 transmembrane receptor protein kinase activity 1/1313 78/18639 0.0128205128205128 0.181996602027067 0.996687263474719 0.999999998407408 GO:0004222 metalloendopeptidase activity 2/1313 110/18639 0.0181818181818182 0.258104271965658 0.997033061885995 0.999999998407408 GO:0004866 endopeptidase inhibitor activity 4/1313 161/18639 0.0248447204968944 0.352689067282266 0.997087477227904 0.999999998407408 GO:0015103 inorganic anion transmembrane transporter activity 4/1313 165/18639 0.0242424242424242 0.344139029287544 0.997677909468849 0.999999998407408 GO:0005254 chloride channel activity 1/1313 83/18639 0.0120481927710843 0.171032951302545 0.997704612854818 0.999999998407408 GO:0005125 cytokine activity 7/1313 234/18639 0.0299145299145299 0.424658738063155 0.997855722233261 0.999999998407408 GO:0022843 voltage-gated monoatomic cation channel activity 3/1313 143/18639 0.020979020979021 0.297812621498836 0.998015745360829 0.999999998407408 GO:0030414 peptidase inhibitor activity 4/1313 169/18639 0.0236686390532544 0.3359937268192 0.998151490351386 0.999999998407408 GO:0008081 phosphoric diester hydrolase activity 1/1313 87/18639 0.0114942528735632 0.163169367334611 0.998288570128019 0.999999998407408 GO:0005244 voltage-gated monoatomic ion channel activity 4/1313 173/18639 0.023121387283237 0.328225085736675 0.998530654778034 0.999999998407408 GO:0003823 antigen binding 4/1313 174/18639 0.0229885057471264 0.326338734669223 0.998612917513765 0.999999998407408 GO:0008509 monoatomic anion transmembrane transporter activity 3/1313 149/18639 0.0201342281879195 0.285820166941836 0.998624060638055 0.999999998407408 GO:0022832 voltage-gated channel activity 4/1313 175/18639 0.0228571428571429 0.324473941899684 0.998690689467972 0.999999998407408 GO:0004867 serine-type endopeptidase inhibitor activity 1/1313 95/18639 0.0105263157894737 0.149428789032749 0.999048782475158 0.999999998407408 GO:0004896 cytokine receptor activity 1/1313 96/18639 0.0104166666666667 0.147872239146992 0.999116133025747 0.999999998407408 GO:0005249 voltage-gated potassium channel activity 1/1313 98/18639 0.0102040816326531 0.144854438348073 0.999236875001988 0.999999998407408 GO:0030527 structural constituent of chromatin 1/1313 98/18639 0.0102040816326531 0.144854438348073 0.999236875001988 0.999999998407408 GO:0099094 ligand-gated monoatomic cation channel activity 2/1313 136/18639 0.0147058823529412 0.208760808207518 0.999468351627685 0.999999998407408 GO:0015291 secondary active transmembrane transporter activity 8/1313 287/18639 0.0278745644599303 0.395699929145957 0.999552230125349 0.999999998407408 GO:0004252 serine-type endopeptidase activity 3/1313 176/18639 0.0170454545454545 0.241972754967804 0.999743603880854 0.999999998407408 GO:0015108 chloride transmembrane transporter activity 1/1313 121/18639 0.00826446280991736 0.117320123620754 0.999859238799467 0.999999998407408 GO:0005267 potassium channel activity 1/1313 124/18639 0.00806451612903226 0.114481733533155 0.999887108983397 0.999999998407408 GO:0008236 serine-type peptidase activity 3/1313 194/18639 0.0154639175257732 0.219521674609967 0.999918413879421 0.999999998407408 GO:0015081 sodium ion transmembrane transporter activity 2/1313 164/18639 0.0121951219512195 0.173118719001356 0.999919593656825 0.999999998407408 GO:0017171 serine hydrolase activity 3/1313 198/18639 0.0151515151515152 0.215086893304715 0.999936889436808 0.999999998407408 GO:0005179 hormone activity 1/1313 132/18639 0.00757575757575758 0.107543446652358 0.999937331246769 0.999999998407408 GO:0022836 gated channel activity 7/1313 318/18639 0.0220125786163522 0.312484731782322 0.999975118816455 0.999999998407408 GO:0015276 ligand-gated monoatomic ion channel activity 2/1313 186/18639 0.010752688172043 0.15264231137754 0.999982139593535 0.999999998407408 GO:0022834 ligand-gated channel activity 2/1313 188/18639 0.0106382978723404 0.151018457001183 0.999984434381454 0.999999998407408 GO:0015079 potassium ion transmembrane transporter activity 1/1313 160/18639 0.00625 0.088723343488195 0.999992028902662 0.999999998407408 GO:0008201 heparin binding 1/1313 172/18639 0.00581395348837209 0.0825333427797163 0.999996709308797 0.999999998407408 GO:0046873 metal ion transmembrane transporter activity 10/1313 450/18639 0.0222222222222222 0.315460776846915 0.999999088384185 0.999999998407408 GO:0005539 glycosaminoglycan binding 2/1313 242/18639 0.00826446280991736 0.117320123620754 0.999999634427718 0.999999998407408 GO:0005261 monoatomic cation channel activity 5/1313 341/18639 0.0146627565982405 0.208148606423918 0.999999723856352 0.999999998407408 GO:0005216 monoatomic ion channel activity 9/1313 448/18639 0.0200892857142857 0.28518217549777 0.999999740679791 0.999999998407408 GO:0030371 translation repressor activity 3/1313 329/18639 0.00911854103343465 0.1294443917153 0.999999989815384 0.999999998407408 GO:0045182 translation regulator activity 3/1313 356/18639 0.00842696629213483 0.119626979984083 0.999999998407408 0.999999998407408