category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Immune system	hsa04611	Platelet activation	5/71	126/9376	5.24033087413369	PLCB2/ITGA2/PLCG2/FERMT3/ARHGAP35	4.18572580987245
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	4/71	108/9376	4.89097548252478	THOC3/XPO1/DDX39B/NUP98	3.55249915488936
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	5/71	187/9376	3.53091812909543	PLCB2/GABARAP/TANK/TRPV2/HSP90AA1	3.05366504668967
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	3/71	78/9376	5.07908992416035	HSPD1/DDX6/PAN3	3.15989341421909
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	5/71	238/9376	2.77429281571784	MX1/RPS10/PLCG2/RPL26/ADAM17	2.42183649606781
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	3/71	98/9376	4.04254096004599	PLCB2/PLCG2/DGKI	2.64471519958628
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	3/71	99/9376	4.00170721297482	PLCB2/PLCG2/TRPV2	2.62264054919093
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	4/71	169/9376	3.12559379948329	VMP1/PLEKHM1/GABARAP/TANK	2.43568532265648
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	4/71	173/9376	3.05332573475535	MX1/XPO1/HLA-DQA2/NUP98	2.38107357163382
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	3/71	103/9376	3.84630110761657	HBS1L/CSTF2T/DDX39B	2.53714885486916
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	2/71	44/9376	6.00256081946223	GTF2H2/GTF2H1	2.90527986578881
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/71	44/9376	6.00256081946223	HSPD1/HLA-DQA2	2.90527986578881
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	3/71	107/9376	3.7025141503225	PLCB2/SIRT1/PHKG1	2.45583988369487
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/71	54/9376	4.89097548252478	HLA-DQA2/CGA	2.50470999437701
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	3/71	122/9376	3.24728700069268	MED14/PLCB2/PLCG2	2.18237979015254
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	2/71	56/9376	4.71629778672032	HSPD1/HBS1L	2.43642578955709
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	2/71	57/9376	4.63355572028663	ACSL4/ELOVL6	2.40348391628028
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	2/71	62/9376	4.25988187187642	ITCH/ADAM17	2.24950112465005
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	4/71	216/9376	2.44548774126239	HSPD1/PLCB2/TANK/HSP90AA1	1.87737130473546
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	2/71	63/9376	4.19226469930695	NSD1/EHMT2	2.22065449129723
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	2/71	63/9376	4.19226469930695	GTF2H2/GTF2H1	2.22065449129723
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/71	65/9376	4.06327193932828	PLCB2/CGA	2.16471482524062
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	2/71	67/9376	3.94198023964684	PLCB2/RPS6KA3	2.11097097223991
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	3/71	142/9376	2.78992263439794	ITCH/HERC4/MGRN1	1.87732784100218
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/71	71/9376	3.71989684586392	PLCG2/ADAM17	2.00946313355117
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	3/71	149/9376	2.65885244352018	PLCB2/PLCG2/DGKI	1.78290110674173
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	2/71	73/9376	3.61798186378545	MX1/XPO1	1.96143164170098
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	2/71	75/9376	3.52150234741784	MAT2A/PSPH	1.91505746409707
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	2/71	75/9376	3.52150234741784	PLCB2/CGA	1.91505746409707
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	3/71	157/9376	2.52336951646183	ADAM17/SIRT1/ATP8A1	1.68139520047453
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	2/71	78/9376	3.38605994944023	PLCB2/PLCG2	1.84837678510363
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	3/71	160/9376	2.47605633802817	NECTIN3/PDCD1/HLA-DQA2	1.64493338901339
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	2/71	82/9376	3.22088629336998	HLA-DQA2/HSP90AA1	1.76436542943167
Metabolism	Lipid metabolism	hsa00061	Fatty acid biosynthesis	1/71	18/9376	7.33646322378717	ACSL4	2.35043515720284
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	2/71	83/9376	3.18208043441371	MTF2/AEBP2	1.74416857179311
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/71	170/9376	2.33040596520298	DPF3/PLCG2/FZD6	1.52907850308378
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	2/71	86/9376	3.07107762856207	PLCB2/KCNMB3	1.68536654951088
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	2/71	90/9376	2.93458528951487	SIRT1/EHMT2	1.61083634509897
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	2/71	91/9376	2.9023370995202	PLCG2/CARD11	1.59284619928571
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	3/71	178/9376	2.22566861845229	PLCB2/FZD6/SIRT1	1.44209207134089
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/71	93/9376	2.83992124791761	PLCB2/CGA	1.55759002650538
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	3/71	181/9376	2.18877908333982	HSPD1/HLA-DQA2/IL10RA	1.41065625695305
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/71	100/9376	2.64112676056338	IL10RA/CCR1	1.44118051275317
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/71	100/9376	2.64112676056338	ITGA2/HLA-DQA2	1.44118051275317
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	2/71	101/9376	2.61497699065681	PLCB2/FZD6	1.42536697001721
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/71	101/9376	2.61497699065681	PLCB2/PLCG2	1.42536697001721
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	3/71	193/9376	2.0526891921477	PLCB2/PLCG2/CCR1	1.29075302126199
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	3/71	195/9376	2.03163596966414	PLCB2/PLCG2/HDAC5	1.27161432569088
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	1/71	27/9376	4.89097548252478	ELOVL6	1.76853809974425
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	2/71	105/9376	2.51535881958417	PLCG2/CARD11	1.36396574600333
NA	NA	hsa04517	IgSF CAM signaling	4/71	299/9376	1.76663997362099	NECTIN3/SRGAP3/PLCG2/CD48	1.17682669268449
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/71	28/9376	4.71629778672032	ELOVL6	1.72023109741571
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/71	109/9376	2.42305207391136	HLA-DQA2/HSP90AA1	1.30533229770492
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	3/71	204/9376	1.94200497100249	ITGA2/PLCG2/FZD6	1.18820911358658
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	2/71	110/9376	2.40102432778489	RPS6KA3/HSP90AA1	1.29107804232146
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/71	205/9376	1.93253177602199	GTF2H2/HDAC5/GTF2H1	1.17920373731149
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/71	112/9376	2.35814889336016	HLA-DQA2/IL10RA	1.2630302322251
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/71	32/9376	4.12676056338028	GABARAP	1.54760392975508
Human Diseases	Immune disease	hsa05310	Asthma	1/71	32/9376	4.12676056338028	HLA-DQA2	1.54760392975508
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/71	115/9376	2.29663196570729	PLCB2/PDE4D	1.22206224194043
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/71	116/9376	2.27683341427878	PLCG2/ARHGAP35	1.20868842911429
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/71	33/9376	4.00170721297482	VAMP1	1.50882457197631
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/71	217/9376	1.82566365937561	PTGES3/RPS6KA3/HSP90AA1	1.07489398170343
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/71	119/9376	2.21943425257427	ITCH/ADAM17	1.16937380860622
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/71	34/9376	3.88400994200497	NFIL3	1.47154282009781
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	2/71	120/9376	2.20093896713615	PLCG2/RPS6KA3	1.15652895577096
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	2/71	122/9376	2.16485800046179	PDCD1/CARD11	1.13121401842387
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/71	122/9376	2.16485800046179	PLCB2/PLCG2	1.13121401842387
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	4/71	333/9376	1.58626231865668	MX1/ITGA2/FZD6/OASL	0.951512409029437
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/71	37/9376	3.56909021697754	PLCB2	1.36768679399233
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	3/71	227/9376	1.74523794750884	PLCB2/IL10RA/CCR1	0.992836419477147
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/71	38/9376	3.47516679021497	SIRT1	1.33544484721589
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/71	39/9376	3.38605994944023	MAT2A	1.30426727903132
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/71	39/9376	3.38605994944023	HLA-DQA2	1.30426727903132
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	3/71	235/9376	1.68582559184897	DPF3/ACSL4/RPS6KA3	0.930052335003551
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	2/71	133/9376	1.98580959440856	GABARAP/SIRT1	1.00015891035861
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/71	133/9376	1.98580959440856	PLCG2/CD48	1.00015891035861
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/71	41/9376	3.22088629336998	PSPH	1.24485198117529
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/71	134/9376	1.97099011982342	PLCB2/KCNMB3	0.988873757282595
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/71	42/9376	3.14419852448021	ACSL4	1.21650070112055
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/71	43/9376	3.07107762856207	ACSL4	1.18898560377121
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/71	139/9376	1.90009119464991	PLCB2/HSP90AA1	0.933867077929667
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/71	140/9376	1.88651911468813	PLCB2/HDAC5	0.923138329501842
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/71	45/9376	2.93458528951487	HLA-DQA2	1.13628341306789
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	1/71	46/9376	2.87078995713411	PSMD9	1.11101455275476
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/71	144/9376	1.83411580594679	PLCB2/PSMD9	0.881081987604479
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	3/71	254/9376	1.55972052789176	PLCB2/PLCG2/PHKG1	0.78995014517613
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/71	48/9376	2.75117370892019	PLCB2	1.06245905488492
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/71	50/9376	2.64112676056338	HLA-DQA2	1.01633304788969
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/71	51/9376	2.58933996133665	PLCG2	0.994109204078823
NA	NA	hsa04518	Integrin signaling	2/71	154/9376	1.71501737698921	ITGA2/FERMT3	0.781485675426843
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/71	52/9376	2.53954496208017	CGA	0.972410277105928
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/71	155/9376	1.70395274875057	ITGA2/HLA-DQA2	0.771928314034753
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/71	155/9376	1.70395274875057	PLCB2/FZD6	0.771928314034753
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/71	53/9376	2.49162901939942	PLCB2	0.951212481712911
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	2/71	157/9376	1.68224634430789	FZD6/SMAD7	0.753018697344609
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	2/71	158/9376	1.67159921554644	FZD6/RPS6KA3	0.743664406426498
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/71	54/9376	2.44548774126239	MAT2A	0.930493550666133
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	4/71	388/9376	1.36140554668215	PLCB2/FZD6/PSMD9/ADAM17	0.635090722245565
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/71	56/9376	2.35814889336016	MGRN1	0.890410074689247
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	2/71	166/9376	1.59104021720686	PLCB2/KCNMB3	0.671116453091563
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/71	59/9376	2.23824301742659	NT5C3B	0.833394192078626
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/71	59/9376	2.23824301742659	CGA	0.833394192078626
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/71	60/9376	2.20093896713615	PLCG2	0.815151713481756
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/71	60/9376	2.20093896713615	PLCB2	0.815151713481756
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/71	62/9376	2.12994093593821	SIRT1	0.779722550105181
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	2/71	174/9376	1.51788894285252	HSPH1/HSP90AA1	0.60231929007308
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/71	63/9376	2.09613234965348	PTGES3	0.762509207285546
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/71	63/9376	2.09613234965348	FZD6	0.762509207285546
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/71	65/9376	2.03163596966414	DGKI	0.72902364596241
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/71	65/9376	2.03163596966414	PLCB2	0.72902364596241
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/71	66/9376	2.00085360648741	HLA-DQA2	0.71272880230442
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	2/71	184/9376	1.43539497856705	SRGAP3/PLCG2	0.521007462077777
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/71	69/9376	1.91385997142274	PLCG2	0.665512117106343
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/71	69/9376	1.91385997142274	PLCB2	0.665512117106343
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/71	69/9376	1.91385997142274	SIRT1	0.665512117106343
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/71	70/9376	1.88651911468813	ACSL4	0.650297708738847
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/71	70/9376	1.88651911468813	HLA-DQA2	0.650297708738847
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/71	71/9376	1.85994842293196	CGA	0.635330952078209
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/71	72/9376	1.83411580594679	TANK	0.620603716515643
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/71	73/9376	1.80899093189273	PLCG2	0.606108252166867
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/71	196/9376	1.34751365334866	PLCG2/CCR1	0.429472332600154
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/71	76/9376	1.73758339510749	ACSL4	0.563940229550126
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/71	76/9376	1.73758339510749	PLCB2	0.563940229550126
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/71	76/9376	1.73758339510749	PLCG2	0.563940229550126
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	3/71	323/9376	1.22652945536999	PLCG2/SIRT1/HDAC5	0.361898102185884
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/71	78/9376	1.69302997472012	HLA-DQA2	0.536860155988175
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/71	80/9376	1.65070422535211	PLCG2	0.510548714038414
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	2/71	203/9376	1.30104766530216	ITGA2/ARHGAP35	0.378777531596375
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	2/71	205/9376	1.28835451734799	HLA-DQA2/PLCG2	0.364629638657359
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	2/71	205/9376	1.28835451734799	PDK3/PLCB2	0.364629638657359
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/71	83/9376	1.59104021720686	ACSL4	0.47242702663935
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/71	85/9376	1.55360397680199	NT5C3B	0.447851525474798
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/71	86/9376	1.53553881428103	PLCG2	0.43580172520169
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/71	86/9376	1.53553881428103	PLCB2	0.43580172520169
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/71	86/9376	1.53553881428103	ITGA2	0.43580172520169
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/71	89/9376	1.48377907896819	ITGA2	0.400553921330892
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/71	89/9376	1.48377907896819	PLCB2	0.400553921330892
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/71	89/9376	1.48377907896819	GABARAP	0.400553921330892
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	4/71	480/9376	1.10046948356808	PLCB2/FZD6/PSMD9/TANK	0.197384945154193
NA	NA	hsa04081	Hormone signaling	2/71	219/9376	1.20599395459515	PLCB2/CGA	0.269436575017881
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/71	90/9376	1.46729264475743	PDCD1	0.389092163603423
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/71	91/9376	1.4511685497601	PDE4D	0.37776801488226
Genetic Information Processing	Translation	hsa03010	Ribosome	2/71	222/9376	1.18969673899251	RPS10/RPL26	0.249854699321483
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/71	93/9376	1.41996062395881	NECTIN3	0.355518737632679
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/71	93/9376	1.41996062395881	HLA-DQA2	0.355518737632679
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/71	93/9376	1.41996062395881	PLCB2	0.355518737632679
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/71	93/9376	1.41996062395881	ITGA2	0.355518737632679
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/71	224/9376	1.17907444668008	XPO1/HLA-DQA2	0.236949744739487
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/71	94/9376	1.40485465987414	HSP90AA1	0.344587017347681
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/71	226/9376	1.16864015954132	PDE4D/CGA	0.224161642810487
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/71	95/9376	1.39006671608599	HLA-DQA2	0.333779710936524
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/71	97/9376	1.36140554668215	PLCB2	0.312526405679761
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/71	98/9376	1.34751365334866	PLCG2	0.302074697808201
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/71	98/9376	1.34751365334866	PLCB2	0.302074697808201
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	2/71	232/9376	1.13841670713939	ITGA2/ARHGAP35	0.186475173958765
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	2/71	233/9376	1.13353079852506	NEBL/ITGA2	0.18029001322311
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/71	99/9376	1.33390240432494	HLA-DQA2	0.291735976536855
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/71	99/9376	1.33390240432494	DGKI	0.291735976536855
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/71	99/9376	1.33390240432494	ITGA2	0.291735976536855
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	3/71	368/9376	1.07654623392529	PSMD9/TANK/NUP98	0.130854955073771
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/71	102/9376	1.29466998066832	PLCB2	0.261371998474993
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/71	103/9376	1.28210036920552	PLCB2	0.25145991292794
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/71	103/9376	1.28210036920552	PLCB2	0.25145991292794
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/71	104/9376	1.26977248104009	DGKI	0.241648569222516
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/71	105/9376	1.25767940979209	GABARAP	0.23193575268411
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/71	105/9376	1.25767940979209	PLCG2	0.23193575268411
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/71	105/9376	1.25767940979209	ITGA2	0.23193575268411
Genetic Information Processing	Transcription	hsa03040	Spliceosome	2/71	243/9376	1.08688344056106	THOC3/DDX39B	0.119864352123582
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/71	106/9376	1.24581450969971	HSP90AA1	0.222319319178223
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	2/71	248/9376	1.0649704679691	PLEKHM1/HSP90AA1	0.0905754798357173
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/71	109/9376	1.21152603695568	RPS6KA3	0.194027873544261
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/71	110/9376	1.20051216389245	PLCG2	0.184776842832701
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/71	110/9376	1.20051216389245	SMAD7	0.184776842832701
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/71	253/9376	1.04392362077604	PLCB2/PLCG2	0.0618651656738287
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/71	115/9376	1.14831598285364	PLCB2	0.139786282704247
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/71	115/9376	1.14831598285364	PLCB2	0.139786282704247
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/71	116/9376	1.13841670713939	PSPH	0.131029365651416
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/71	116/9376	1.13841670713939	PLCB2	0.131029365651416
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/71	117/9376	1.12868664981341	DPF3	0.122349164334744
NA	NA	hsa04519	Cadherin signaling	3/71	404/9376	0.980616371496305	FZD6/TAOK2/ARHGAP35	-0.0347886640767332
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/71	122/9376	1.08242900023089	SIRT1	0.0800482466952078
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/71	125/9376	1.05645070422535	PLCB2	0.0554991911843179
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/71	128/9376	1.03169014084507	PDE4D	0.0315327514437891
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/71	130/9376	1.01581798483207	PLCB2	0.0158636277450037
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/71	133/9376	0.992904797204278	PLCB2	-0.0071984796427142
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/71	136/9376	0.971002485501243	MX1	-0.029754377360203
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/71	138/9376	0.95692998571137	RPS6KA3	-0.0445227728318985
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/71	138/9376	0.95692998571137	PHKG1	-0.0445227728318985
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/71	138/9376	0.95692998571137	RPS6KA3	-0.0445227728318985
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/71	142/9376	0.929974211465979	PLCG2	-0.0734452762799257
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/71	142/9376	0.929974211465979	HSP90AA1	-0.0734452762799257
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/71	298/9376	0.88628414784006	IL10RA/CCR1	-0.174257178110984
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/71	143/9376	0.923470895301881	HLA-DQA2	-0.0805526546552627
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/71	144/9376	0.917057902973396	FZD6	-0.0876122801933159
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/71	144/9376	0.917057902973396	SIRT1	-0.0876122801933159
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/71	300/9376	0.88037558685446	TAOK2/RPS6KA3	-0.183945779537495
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/71	148/9376	0.892272554244385	FZD6	-0.115387842039126
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/71	149/9376	0.88628414784006	PLCB2	-0.122219501476455
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	2/71	308/9376	0.857508688494604	PLCB2/PSMD9	-0.222108208997101
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/71	150/9376	0.88037558685446	FZD6	-0.129007615611566
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/71	154/9376	0.857508688494604	MAT2A	-0.155737360234718
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/71	154/9376	0.857508688494604	PLCB2	-0.155737360234718
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	1/71	154/9376	0.857508688494604	PLCB2	-0.155737360234718
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/71	156/9376	0.846514987360058	MX1	-0.168857142954421
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/71	157/9376	0.841123172153943	SIRT1	-0.175357805785313
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	1/71	157/9376	0.841123172153943	ITCH	-0.175357805785313
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/71	168/9376	0.786049631120054	HSP90AA1	-0.244422762913619
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/71	168/9376	0.786049631120054	IL10RA	-0.244422762913619
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/71	170/9376	0.776801988400994	RAB8B	-0.256528676504403
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/71	180/9376	0.733646322378717	HLA-DQA2	-0.315175240331083
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	1/71	183/9376	0.721619333487262	XPO1	-0.332194630948232
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	2/71	362/9376	0.729593027779939	ITGA2/HSP90AA1	-0.458321275168526
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/71	191/9376	0.691394439938058	HDAC5	-0.376389477398414
NA	NA	hsa04082	Neuroactive ligand signaling	1/71	199/9376	0.663599688583764	PLCB2	-0.418976037766299
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/71	201/9376	0.656996706607806	KDM6A	-0.42938800289117
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/71	212/9376	0.622907254849854	PLCB2	-0.485098789797641
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/71	214/9376	0.617085691720416	PLCG2	-0.494959838861222
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/71	238/9376	0.554858563143567	PLCG2	-0.607599697265762
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/71	250/9376	0.528225352112676	PLEKHM1	-0.660421183462834
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/71	250/9376	0.528225352112676	ITCH	-0.660421183462834
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	1/71	268/9376	0.492747529955854	PSMD9	-0.735930293437562
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	1/71	275/9376	0.480204865556978	PSMD9	-0.764206317405135
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/71	370/9376	0.356909021697754	CGA	-1.1024627681664
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/71	449/9376	0.294112111421312	OR11G2	-1.33894506038832