ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0140662 ATP-dependent protein folding chaperone 4/158 40/18639 0.1 11.796835443038 0.000358168405850476 0.0935345433119885 GO:0044389 ubiquitin-like protein ligase binding 10/158 322/18639 0.031055900621118 3.6636134916267 0.000432030223150062 0.0935345433119885 GO:0031625 ubiquitin protein ligase binding 9/158 302/18639 0.0298013245033113 3.51561321150138 0.00111588436551089 0.134050678335979 GO:0004435 phosphatidylinositol phospholipase C activity 3/158 26/18639 0.115384615384615 13.6117332035054 0.0013465258041711 0.134050678335979 GO:0046966 nuclear thyroid hormone receptor binding 3/158 28/18639 0.107142857142857 12.6394665461121 0.0016757111317063 0.134050678335979 GO:0004629 phospholipase C activity 3/158 29/18639 0.103448275862069 12.2036228721082 0.00185751517324682 0.134050678335979 GO:0002039 p53 binding 4/158 69/18639 0.0579710144927536 6.83874518436984 0.00280179462823133 0.167225320601472 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/158 11/18639 0.181818181818182 21.4487917146145 0.00373493634969561 0.167225320601472 GO:0044183 protein folding chaperone 4/158 75/18639 0.0533333333333333 6.29164556962025 0.00378803386249551 0.167225320601472 GO:0042578 phosphoric ester hydrolase activity 9/158 363/18639 0.0247933884297521 2.92483523381107 0.00386201664206632 0.167225320601472 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/158 12/18639 0.166666666666667 19.6613924050633 0.00445706283263539 0.175446200593739 GO:0048487 beta-tubulin binding 3/158 42/18639 0.0714285714285714 8.42631103074141 0.00538536413965998 0.17762161292815 GO:0051879 Hsp90 protein binding 3/158 42/18639 0.0714285714285714 8.42631103074141 0.00538536413965998 0.17762161292815 GO:0016922 nuclear receptor binding 5/158 137/18639 0.0364963503649635 4.30541439526933 0.00626175647055726 0.17762161292815 GO:0008081 phosphoric diester hydrolase activity 4/158 87/18639 0.0459770114942529 5.42383238760367 0.00641618024396178 0.17762161292815 GO:0141050 histone H3K deacetylase activity 2/158 15/18639 0.133333333333333 15.7291139240506 0.0069735968124216 0.17762161292815 GO:0141051 histone H4K deacetylase activity 2/158 15/18639 0.133333333333333 15.7291139240506 0.0069735968124216 0.17762161292815 GO:0001222 transcription corepressor binding 3/158 49/18639 0.0612244897959184 7.22255231206407 0.00827839480693295 0.199141386188998 GO:0070182 DNA polymerase binding 2/158 21/18639 0.0952380952380952 11.2350813743219 0.0134913853304721 0.273226837064614 GO:0000287 magnesium ion binding 6/158 230/18639 0.0260869565217391 3.07743533296643 0.0137692093831008 0.273226837064614 GO:0004407 histone deacetylase activity 2/158 22/18639 0.0909090909090909 10.7243958573073 0.0147587627212058 0.273226837064614 GO:0033558 protein lysine deacetylase activity 2/158 22/18639 0.0909090909090909 10.7243958573073 0.0147587627212058 0.273226837064614 GO:0050321 tau-protein kinase activity 2/158 22/18639 0.0909090909090909 10.7243958573073 0.0147587627212058 0.273226837064614 GO:0001221 transcription coregulator binding 4/158 115/18639 0.0347826086956522 4.1032471106219 0.0166261654617698 0.273226837064614 GO:0015631 tubulin binding 8/158 385/18639 0.0207792207792208 2.45129048167023 0.0170590512963402 0.273226837064614 GO:0048027 mRNA 5'-UTR binding 2/158 24/18639 0.0833333333333333 9.83069620253165 0.0174402799786065 0.273226837064614 GO:1990782 protein tyrosine kinase binding 4/158 117/18639 0.0341880341880342 4.03310613437196 0.0176012994422134 0.273226837064614 GO:0042054 histone methyltransferase activity 3/158 67/18639 0.0447761194029851 5.28216512374835 0.019278781615146 0.273226837064614 GO:0051082 unfolded protein binding 4/158 121/18639 0.0330578512396694 3.89978031174809 0.0196568631873749 0.273226837064614 GO:1990841 promoter-specific chromatin binding 3/158 68/18639 0.0441176470588235 5.2044862248697 0.0200459565736751 0.273226837064614 GO:0016279 protein-lysine N-methyltransferase activity 3/158 69/18639 0.0434782608695652 5.12905888827738 0.0208297821166499 0.273226837064614 GO:0016278 lysine N-methyltransferase activity 3/158 70/18639 0.0428571428571429 5.05578661844485 0.0216302677087199 0.273226837064614 GO:0097110 scaffold protein binding 3/158 70/18639 0.0428571428571429 5.05578661844485 0.0216302677087199 0.273226837064614 GO:0023026 MHC class II protein complex binding 2/158 27/18639 0.0740740740740741 8.73839662447257 0.0218159195668882 0.273226837064614 GO:0003713 transcription coactivator activity 6/158 256/18639 0.0234375 2.76488330696203 0.0220853101553383 0.273226837064614 GO:0051537 2 iron, 2 sulfur cluster binding 2/158 28/18639 0.0714285714285714 8.42631103074141 0.0233651663695945 0.281031028834289 GO:0003712 transcription coregulator activity 9/158 495/18639 0.0181818181818182 2.14487917146145 0.0254196237400873 0.289698944220135 GO:0031072 heat shock protein binding 4/158 131/18639 0.0305343511450382 3.60208715817953 0.0254239258207047 0.289698944220135 GO:0051087 protein-folding chaperone binding 4/158 134/18639 0.0298507462686567 3.52144341583223 0.0273324976655367 0.303460807414805 GO:0043425 bHLH transcription factor binding 2/158 32/18639 0.0625 7.37302215189873 0.0299928764648269 0.324672887731752 GO:0019213 deacetylase activity 2/158 37/18639 0.0540540540540541 6.37666780704755 0.0391852452553537 0.367656121486876 GO:0023023 MHC protein complex binding 2/158 37/18639 0.0540540540540541 6.37666780704755 0.0391852452553537 0.367656121486876 GO:0008276 protein methyltransferase activity 3/158 95/18639 0.0315789473684211 3.7253164556962 0.0470073168242147 0.367656121486876 GO:0008170 N-methyltransferase activity 3/158 98/18639 0.0306122448979592 3.61127615603203 0.0507290328615357 0.367656121486876 GO:0048156 tau protein binding 2/158 43/18639 0.0465116279069767 5.48690020606417 0.0514192804689017 0.367656121486876 GO:0140303 intramembrane lipid transporter activity 2/158 45/18639 0.0444444444444444 5.24303797468354 0.0557635351292649 0.367656121486876 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/158 243/18639 0.0205761316872428 2.42733239568683 0.0562132095682489 0.367656121486876 GO:0140297 DNA-binding transcription factor binding 8/158 488/18639 0.0163934426229508 1.93390744967836 0.056414772015548 0.367656121486876 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0004711 ribosomal protein S6 kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0035175 histone H3S10 kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0035979 histone H2AXS139 kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0044022 histone H3S28 kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0044023 histone H4S1 kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0044024 histone H2AS1 kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0044025 histone H2BS14 kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0072354 histone H3T3 kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0072371 histone H2AS121 kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0140823 histone H2BS36 kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0140855 histone H3S57 kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0140995 histone H2A kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0140997 histone H4 kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0140998 histone H2B kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:1990244 histone H2AT120 kinase activity 5/158 245/18639 0.0204081632653061 2.40751743735469 0.0578223625753851 0.367656121486876 GO:0004677 DNA-dependent protein kinase activity 5/158 246/18639 0.0203252032520325 2.39773078110528 0.0586368058484944 0.367656121486876 GO:0140857 histone H3T45 kinase activity 5/158 246/18639 0.0203252032520325 2.39773078110528 0.0586368058484944 0.367656121486876 GO:0035402 histone H3T11 kinase activity 5/158 247/18639 0.0202429149797571 2.38802336903603 0.0594578241626331 0.367656121486876 GO:0035403 histone H3T6 kinase activity 5/158 247/18639 0.0202429149797571 2.38802336903603 0.0594578241626331 0.367656121486876 GO:0140938 histone H3 methyltransferase activity 2/158 47/18639 0.0425531914893617 5.01992997576084 0.0602316086060052 0.367656121486876 GO:0004679 AMP-activated protein kinase activity 5/158 248/18639 0.0201612903225806 2.37839424254798 0.0602854148396493 0.367656121486876 GO:0140693 molecular condensate scaffold activity 2/158 48/18639 0.0416666666666667 4.91534810126582 0.0625103970371176 0.375930582181554 GO:0060590 ATPase regulator activity 2/158 49/18639 0.0408163265306122 4.81503487470938 0.0648181418128701 0.383540035785095 GO:0004620 phospholipase activity 3/158 109/18639 0.0275229357798165 3.24683544303797 0.0655472578477991 0.383540035785095 GO:0030159 signaling receptor complex adaptor activity 2/158 52/18639 0.0384615384615385 4.53724440116845 0.0719086832567117 0.38594898274115 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 6/158 349/18639 0.0171919770773639 2.02810924522143 0.0770388748778753 0.38594898274115 GO:0061630 ubiquitin protein ligase activity 6/158 353/18639 0.0169971671388102 2.00512783734357 0.08036017001621 0.38594898274115 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/158 10/18639 0.1 11.796835443038 0.0816259156444397 0.38594898274115 GO:0031434 mitogen-activated protein kinase kinase binding 1/158 10/18639 0.1 11.796835443038 0.0816259156444397 0.38594898274115 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/158 10/18639 0.1 11.796835443038 0.0816259156444397 0.38594898274115 GO:0031996 thioesterase binding 1/158 10/18639 0.1 11.796835443038 0.0816259156444397 0.38594898274115 GO:0032395 MHC class II receptor activity 1/158 10/18639 0.1 11.796835443038 0.0816259156444397 0.38594898274115 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/158 10/18639 0.1 11.796835443038 0.0816259156444397 0.38594898274115 GO:0070097 delta-catenin binding 1/158 10/18639 0.1 11.796835443038 0.0816259156444397 0.38594898274115 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/158 10/18639 0.1 11.796835443038 0.0816259156444397 0.38594898274115 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/158 10/18639 0.1 11.796835443038 0.0816259156444397 0.38594898274115 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/158 10/18639 0.1 11.796835443038 0.0816259156444397 0.38594898274115 GO:1990763 arrestin family protein binding 1/158 10/18639 0.1 11.796835443038 0.0816259156444397 0.38594898274115 GO:0016791 phosphatase activity 5/158 273/18639 0.0183150183150183 2.16059257198498 0.0830942459972417 0.38594898274115 GO:0016504 peptidase activator activity 2/158 57/18639 0.0350877192982456 4.13924050632911 0.0842466488019118 0.38594898274115 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/158 122/18639 0.0245901639344262 2.90086117451754 0.0853017033767291 0.38594898274115 GO:0008017 microtubule binding 5/158 276/18639 0.0181159420289855 2.13710787011558 0.0861014922301274 0.38594898274115 GO:0004842 ubiquitin-protein transferase activity 7/158 449/18639 0.0155902004454343 1.83915029178766 0.0880699333287656 0.38594898274115 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/158 11/18639 0.0909090909090909 10.7243958573073 0.0894150135739141 0.38594898274115 GO:0019215 intermediate filament binding 1/158 11/18639 0.0909090909090909 10.7243958573073 0.0894150135739141 0.38594898274115 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/158 11/18639 0.0909090909090909 10.7243958573073 0.0894150135739141 0.38594898274115 GO:0034713 type I transforming growth factor beta receptor binding 1/158 11/18639 0.0909090909090909 10.7243958573073 0.0894150135739141 0.38594898274115 GO:0047676 arachidonate-CoA ligase activity 1/158 11/18639 0.0909090909090909 10.7243958573073 0.0894150135739141 0.38594898274115 GO:0070697 activin receptor binding 1/158 11/18639 0.0909090909090909 10.7243958573073 0.0894150135739141 0.38594898274115 GO:0140031 phosphorylation-dependent protein binding 1/158 11/18639 0.0909090909090909 10.7243958573073 0.0894150135739141 0.38594898274115 GO:0019905 syntaxin binding 2/158 61/18639 0.0327868852459016 3.86781489935671 0.0945425765711443 0.38594898274115 GO:0003720 telomerase activity 1/158 12/18639 0.0833333333333333 9.83069620253165 0.0971384636413032 0.38594898274115 GO:0005049 nuclear export signal receptor activity 1/158 12/18639 0.0833333333333333 9.83069620253165 0.0971384636413032 0.38594898274115 GO:0005095 GTPase inhibitor activity 1/158 12/18639 0.0833333333333333 9.83069620253165 0.0971384636413032 0.38594898274115 GO:0015269 calcium-activated potassium channel activity 1/158 12/18639 0.0833333333333333 9.83069620253165 0.0971384636413032 0.38594898274115 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/158 12/18639 0.0833333333333333 9.83069620253165 0.0971384636413032 0.38594898274115 GO:0061659 ubiquitin-like protein ligase activity 6/158 372/18639 0.0161290322580645 1.90271539403838 0.0972160141627524 0.38594898274115 GO:0016298 lipase activity 3/158 130/18639 0.0230769230769231 2.72234664070107 0.0985703688296802 0.38594898274115 GO:0003964 RNA-directed DNA polymerase activity 1/158 13/18639 0.0769230769230769 9.07448880233691 0.104796815643487 0.38594898274115 GO:0004535 poly(A)-specific ribonuclease activity 1/158 13/18639 0.0769230769230769 9.07448880233691 0.104796815643487 0.38594898274115 GO:0008035 high-density lipoprotein particle binding 1/158 13/18639 0.0769230769230769 9.07448880233691 0.104796815643487 0.38594898274115 GO:0008253 5'-nucleotidase activity 1/158 13/18639 0.0769230769230769 9.07448880233691 0.104796815643487 0.38594898274115 GO:0009982 pseudouridine synthase activity 1/158 13/18639 0.0769230769230769 9.07448880233691 0.104796815643487 0.38594898274115 GO:0046974 histone H3K9 methyltransferase activity 1/158 13/18639 0.0769230769230769 9.07448880233691 0.104796815643487 0.38594898274115 GO:0046975 histone H3K36 methyltransferase activity 1/158 13/18639 0.0769230769230769 9.07448880233691 0.104796815643487 0.38594898274115 GO:0051011 microtubule minus-end binding 1/158 13/18639 0.0769230769230769 9.07448880233691 0.104796815643487 0.38594898274115 GO:0140333 glycerophospholipid flippase activity 1/158 13/18639 0.0769230769230769 9.07448880233691 0.104796815643487 0.38594898274115 GO:0160215 deacylase activity 2/158 65/18639 0.0307692307692308 3.62979552093476 0.105177782825533 0.38594898274115 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/158 67/18639 0.0298507462686567 3.52144341583223 0.110611943985677 0.394504716246367 GO:0042813 Wnt receptor activity 1/158 14/18639 0.0714285714285714 8.42631103074141 0.1123906148021 0.394504716246367 GO:0070742 C2H2 zinc finger domain binding 1/158 14/18639 0.0714285714285714 8.42631103074141 0.1123906148021 0.394504716246367 GO:0005548 phospholipid transporter activity 2/158 68/18639 0.0294117647058824 3.46965748324646 0.113356367846646 0.394504716246367 GO:0019787 ubiquitin-like protein transferase activity 7/158 479/18639 0.0146137787056367 1.72396342591369 0.11344667265629 0.394504716246367 GO:0140767 enzyme-substrate adaptor activity 3/158 139/18639 0.0215827338129496 2.54607959202258 0.114421449097322 0.394504716246367 GO:0000774 adenyl-nucleotide exchange factor activity 1/158 15/18639 0.0666666666666667 7.86455696202532 0.119920401801363 0.394504716246367 GO:0004467 long-chain fatty acid-CoA ligase activity 1/158 15/18639 0.0666666666666667 7.86455696202532 0.119920401801363 0.394504716246367 GO:0005523 tropomyosin binding 1/158 15/18639 0.0666666666666667 7.86455696202532 0.119920401801363 0.394504716246367 GO:0008252 nucleotidase activity 1/158 15/18639 0.0666666666666667 7.86455696202532 0.119920401801363 0.394504716246367 GO:0031005 filamin binding 1/158 15/18639 0.0666666666666667 7.86455696202532 0.119920401801363 0.394504716246367 GO:0042809 nuclear vitamin D receptor binding 1/158 15/18639 0.0666666666666667 7.86455696202532 0.119920401801363 0.394504716246367 GO:0050700 CARD domain binding 1/158 15/18639 0.0666666666666667 7.86455696202532 0.119920401801363 0.394504716246367 GO:0019955 cytokine binding 3/158 144/18639 0.0208333333333333 2.45767405063291 0.12361898531098 0.394504716246367 GO:0005518 collagen binding 2/158 72/18639 0.0277777777777778 3.27689873417722 0.124504835665927 0.394504716246367 GO:0003688 DNA replication origin binding 1/158 16/18639 0.0625 7.37302215189873 0.127386712825599 0.394504716246367 GO:0017070 U6 snRNA binding 1/158 16/18639 0.0625 7.37302215189873 0.127386712825599 0.394504716246367 GO:0034450 ubiquitin-ubiquitin ligase activity 1/158 16/18639 0.0625 7.37302215189873 0.127386712825599 0.394504716246367 GO:0070411 I-SMAD binding 1/158 16/18639 0.0625 7.37302215189873 0.127386712825599 0.394504716246367 GO:0140327 flippase activity 1/158 16/18639 0.0625 7.37302215189873 0.127386712825599 0.394504716246367 GO:0140328 floppase activity 1/158 16/18639 0.0625 7.37302215189873 0.127386712825599 0.394504716246367 GO:0016755 aminoacyltransferase activity 7/158 496/18639 0.0141129032258065 1.66487596978359 0.129375411715074 0.394504716246367 GO:0003725 double-stranded RNA binding 2/158 75/18639 0.0266666666666667 3.14582278481013 0.133032162308957 0.394504716246367 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/158 17/18639 0.0588235294117647 6.93931496649293 0.13479007959645 0.394504716246367 GO:0008429 phosphatidylethanolamine binding 1/158 17/18639 0.0588235294117647 6.93931496649293 0.13479007959645 0.394504716246367 GO:0038191 neuropilin binding 1/158 17/18639 0.0588235294117647 6.93931496649293 0.13479007959645 0.394504716246367 GO:0045236 CXCR chemokine receptor binding 1/158 17/18639 0.0588235294117647 6.93931496649293 0.13479007959645 0.394504716246367 GO:0046965 nuclear retinoid X receptor binding 1/158 17/18639 0.0588235294117647 6.93931496649293 0.13479007959645 0.394504716246367 GO:0070403 NAD+ binding 1/158 17/18639 0.0588235294117647 6.93931496649293 0.13479007959645 0.394504716246367 GO:0051536 iron-sulfur cluster binding 2/158 76/18639 0.0263157894736842 3.10443037974684 0.135903759793971 0.394504716246367 GO:0098631 cell adhesion mediator activity 2/158 76/18639 0.0263157894736842 3.10443037974684 0.135903759793971 0.394504716246367 GO:0003724 RNA helicase activity 2/158 77/18639 0.025974025974026 3.06411310208779 0.138789191109245 0.394504716246367 GO:0051540 metal cluster binding 2/158 77/18639 0.025974025974026 3.06411310208779 0.138789191109245 0.394504716246367 GO:0003746 translation elongation factor activity 1/158 18/18639 0.0555555555555556 6.55379746835443 0.142131029409777 0.394504716246367 GO:0017128 phospholipid scramblase activity 1/158 18/18639 0.0555555555555556 6.55379746835443 0.142131029409777 0.394504716246367 GO:0031690 adrenergic receptor binding 1/158 18/18639 0.0555555555555556 6.55379746835443 0.142131029409777 0.394504716246367 GO:0034185 apolipoprotein binding 1/158 18/18639 0.0555555555555556 6.55379746835443 0.142131029409777 0.394504716246367 GO:0050811 GABA receptor binding 1/158 18/18639 0.0555555555555556 6.55379746835443 0.142131029409777 0.394504716246367 GO:0016887 ATP hydrolysis activity 6/158 417/18639 0.0143884892086331 1.69738639468172 0.143937467413703 0.396276708160008 GO:0008186 ATP-dependent activity, acting on RNA 2/158 79/18639 0.0253164556962025 2.98654061849063 0.144599814986793 0.396276708160008 GO:0140375 immune receptor activity 3/158 156/18639 0.0192307692307692 2.26862220058423 0.14672328252524 0.399567178197665 GO:0043395 heparan sulfate proteoglycan binding 1/158 19/18639 0.0526315789473684 6.20886075949367 0.149410085172263 0.401829607947763 GO:0050145 nucleoside monophosphate kinase activity 1/158 19/18639 0.0526315789473684 6.20886075949367 0.149410085172263 0.401829607947763 GO:0003924 GTPase activity 5/158 331/18639 0.0151057401812689 1.78199931163716 0.150745045879558 0.40291731398672 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/158 82/18639 0.024390243902439 2.87727693732634 0.153408792390301 0.407521515981596 GO:0140939 histone H4 methyltransferase activity 1/158 20/18639 0.05 5.89841772151899 0.156627765437718 0.409645755619209 GO:0005178 integrin binding 3/158 161/18639 0.0186335403726708 2.19816809497602 0.156740059059623 0.409645755619209 GO:0051117 ATPase binding 2/158 84/18639 0.0238095238095238 2.80877034358047 0.159338666888506 0.409645755619209 GO:0042277 peptide binding 4/158 249/18639 0.0160642570281124 1.89507396675309 0.16151530685882 0.409645755619209 GO:0004674 protein serine/threonine kinase activity 6/158 433/18639 0.0138568129330254 1.63466541935861 0.162672022017446 0.409645755619209 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/158 21/18639 0.0476190476190476 5.61754068716094 0.163784584443081 0.409645755619209 GO:0072542 protein phosphatase activator activity 1/158 21/18639 0.0476190476190476 5.61754068716094 0.163784584443081 0.409645755619209 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/158 167/18639 0.0179640718562874 2.11919199575532 0.169031163661362 0.409645755619209 GO:0016874 ligase activity 3/158 167/18639 0.0179640718562874 2.11919199575532 0.169031163661362 0.409645755619209 GO:0016881 acid-amino acid ligase activity 1/158 22/18639 0.0454545454545455 5.36219792865363 0.170881052144122 0.409645755619209 GO:0031683 G-protein beta/gamma-subunit complex binding 1/158 22/18639 0.0454545454545455 5.36219792865363 0.170881052144122 0.409645755619209 GO:0061133 endopeptidase activator activity 1/158 22/18639 0.0454545454545455 5.36219792865363 0.170881052144122 0.409645755619209 GO:0140517 protein-RNA adaptor activity 1/158 22/18639 0.0454545454545455 5.36219792865363 0.170881052144122 0.409645755619209 GO:0016493 C-C chemokine receptor activity 1/158 23/18639 0.0434782608695652 5.12905888827738 0.177917674250865 0.409645755619209 GO:0031681 G-protein beta-subunit binding 1/158 23/18639 0.0434782608695652 5.12905888827738 0.177917674250865 0.409645755619209 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/158 23/18639 0.0434782608695652 5.12905888827738 0.177917674250865 0.409645755619209 GO:0140030 modification-dependent protein binding 3/158 173/18639 0.0173410404624277 2.04569400746323 0.181592425384971 0.409645755619209 GO:0141003 histone H2AX kinase activity 5/158 354/18639 0.0141242937853107 1.66621969534435 0.182515805913159 0.409645755619209 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/158 24/18639 0.0416666666666667 4.91534810126582 0.184894952262702 0.409645755619209 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/158 24/18639 0.0416666666666667 4.91534810126582 0.184894952262702 0.409645755619209 GO:0019957 C-C chemokine binding 1/158 24/18639 0.0416666666666667 4.91534810126582 0.184894952262702 0.409645755619209 GO:0030552 cAMP binding 1/158 24/18639 0.0416666666666667 4.91534810126582 0.184894952262702 0.409645755619209 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/158 24/18639 0.0416666666666667 4.91534810126582 0.184894952262702 0.409645755619209 GO:0004721 phosphoprotein phosphatase activity 3/158 175/18639 0.0171428571428571 2.02231464737794 0.185834935377078 0.409645755619209 GO:0140996 histone H3 kinase activity 5/158 357/18639 0.0140056022408964 1.65221784916498 0.186834046889959 0.409645755619209 GO:0035173 histone kinase activity 5/158 360/18639 0.0138888888888889 1.63844936708861 0.191189545852742 0.409645755619209 GO:0004709 MAP kinase kinase kinase activity 1/158 25/18639 0.04 4.71873417721519 0.191813383503233 0.409645755619209 GO:0008139 nuclear localization sequence binding 1/158 25/18639 0.04 4.71873417721519 0.191813383503233 0.409645755619209 GO:0015645 fatty acid ligase activity 1/158 25/18639 0.04 4.71873417721519 0.191813383503233 0.409645755619209 GO:0017056 structural constituent of nuclear pore 1/158 25/18639 0.04 4.71873417721519 0.191813383503233 0.409645755619209 GO:0019211 phosphatase activator activity 1/158 25/18639 0.04 4.71873417721519 0.191813383503233 0.409645755619209 GO:0042974 nuclear retinoic acid receptor binding 1/158 25/18639 0.04 4.71873417721519 0.191813383503233 0.409645755619209 GO:0120515 fatty acid-CoA ligase activity 1/158 25/18639 0.04 4.71873417721519 0.191813383503233 0.409645755619209 GO:0106310 protein serine kinase activity 5/158 361/18639 0.0138504155124654 1.63391072618254 0.192649495979114 0.409645755619209 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 4/158 268/18639 0.0149253731343284 1.76072170791612 0.193231312733834 0.409645755619209 GO:0004896 cytokine receptor activity 2/158 96/18639 0.0208333333333333 2.45767405063291 0.195696439781933 0.409645755619209 GO:0016853 isomerase activity 3/158 180/18639 0.0166666666666667 1.96613924050633 0.196553196249969 0.409645755619209 GO:0001637 G protein-coupled chemoattractant receptor activity 1/158 26/18639 0.0384615384615385 4.53724440116845 0.198673461154813 0.409645755619209 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/158 26/18639 0.0384615384615385 4.53724440116845 0.198673461154813 0.409645755619209 GO:0004950 chemokine receptor activity 1/158 26/18639 0.0384615384615385 4.53724440116845 0.198673461154813 0.409645755619209 GO:0005112 Notch binding 1/158 26/18639 0.0384615384615385 4.53724440116845 0.198673461154813 0.409645755619209 GO:0005160 transforming growth factor beta receptor binding 1/158 26/18639 0.0384615384615385 4.53724440116845 0.198673461154813 0.409645755619209 GO:0005227 calcium-activated cation channel activity 1/158 26/18639 0.0384615384615385 4.53724440116845 0.198673461154813 0.409645755619209 GO:0008143 poly(A) binding 1/158 26/18639 0.0384615384615385 4.53724440116845 0.198673461154813 0.409645755619209 GO:0050681 nuclear androgen receptor binding 1/158 26/18639 0.0384615384615385 4.53724440116845 0.198673461154813 0.409645755619209 GO:0070006 metalloaminopeptidase activity 1/158 26/18639 0.0384615384615385 4.53724440116845 0.198673461154813 0.409645755619209 GO:0097602 cullin family protein binding 1/158 26/18639 0.0384615384615385 4.53724440116845 0.198673461154813 0.409645755619209 GO:0001671 ATPase activator activity 1/158 27/18639 0.037037037037037 4.36919831223629 0.205475674292809 0.415752182097133 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/158 27/18639 0.037037037037037 4.36919831223629 0.205475674292809 0.415752182097133 GO:0016405 CoA-ligase activity 1/158 27/18639 0.037037037037037 4.36919831223629 0.205475674292809 0.415752182097133 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/158 27/18639 0.037037037037037 4.36919831223629 0.205475674292809 0.415752182097133 GO:0001217 DNA-binding transcription repressor activity 4/158 278/18639 0.0143884892086331 1.69738639468172 0.21065737991842 0.4195957987634 GO:0016866 intramolecular transferase activity 1/158 28/18639 0.0357142857142857 4.21315551537071 0.212220507919595 0.4195957987634 GO:0051019 mitogen-activated protein kinase binding 1/158 28/18639 0.0357142857142857 4.21315551537071 0.212220507919595 0.4195957987634 GO:0097718 disordered domain specific binding 1/158 28/18639 0.0357142857142857 4.21315551537071 0.212220507919595 0.4195957987634 GO:0141052 histone H3 demethylase activity 1/158 28/18639 0.0357142857142857 4.21315551537071 0.212220507919595 0.4195957987634 GO:0004722 protein serine/threonine phosphatase activity 2/158 103/18639 0.0194174757281553 2.29064765884233 0.217358035023083 0.426970071253329 GO:0005525 GTP binding 5/158 378/18639 0.0132275132275132 1.56042796865582 0.218051741385475 0.426970071253329 GO:0043236 laminin binding 1/158 29/18639 0.0344827586206897 4.06787429070275 0.218908442998243 0.426970071253329 GO:0022839 monoatomic ion-gated channel activity 1/158 30/18639 0.0333333333333333 3.93227848101266 0.225539956485952 0.430214983076729 GO:0031624 ubiquitin conjugating enzyme binding 1/158 30/18639 0.0333333333333333 3.93227848101266 0.225539956485952 0.430214983076729 GO:0032452 histone demethylase activity 1/158 30/18639 0.0333333333333333 3.93227848101266 0.225539956485952 0.430214983076729 GO:0033612 receptor serine/threonine kinase binding 1/158 30/18639 0.0333333333333333 3.93227848101266 0.225539956485952 0.430214983076729 GO:0048019 receptor antagonist activity 1/158 30/18639 0.0333333333333333 3.93227848101266 0.225539956485952 0.430214983076729 GO:0000149 SNARE binding 2/158 106/18639 0.0188679245283019 2.22581800812037 0.226708509241535 0.430547300445546 GO:0019888 protein phosphatase regulator activity 2/158 107/18639 0.0186915887850467 2.2050159706613 0.229832114474051 0.433215606689652 GO:0016878 acid-thiol ligase activity 1/158 31/18639 0.032258064516129 3.80543078807677 0.232115521367204 0.433215606689652 GO:0017147 Wnt-protein binding 1/158 31/18639 0.032258064516129 3.80543078807677 0.232115521367204 0.433215606689652 GO:0140457 protein demethylase activity 1/158 31/18639 0.032258064516129 3.80543078807677 0.232115521367204 0.433215606689652 GO:0030695 GTPase regulator activity 6/158 489/18639 0.0122699386503067 1.4474644715384 0.235480773102608 0.434156376871064 GO:0060589 nucleoside-triphosphatase regulator activity 6/158 490/18639 0.0122448979591837 1.44451046241281 0.236867363491304 0.434156376871064 GO:0070717 poly-purine tract binding 1/158 32/18639 0.03125 3.68651107594937 0.238635606686636 0.434156376871064 GO:0071813 lipoprotein particle binding 1/158 32/18639 0.03125 3.68651107594937 0.238635606686636 0.434156376871064 GO:0071814 protein-lipid complex binding 1/158 32/18639 0.03125 3.68651107594937 0.238635606686636 0.434156376871064 GO:0140142 nucleocytoplasmic carrier activity 1/158 32/18639 0.03125 3.68651107594937 0.238635606686636 0.434156376871064 GO:0019956 chemokine binding 1/158 33/18639 0.0303030303030303 3.57479861910242 0.245100677581649 0.442202472470225 GO:0140416 transcription regulator inhibitor activity 1/158 33/18639 0.0303030303030303 3.57479861910242 0.245100677581649 0.442202472470225 GO:0003714 transcription corepressor activity 3/158 204/18639 0.0147058823529412 1.73482874162323 0.249803299463208 0.446962101932104 GO:0008168 methyltransferase activity 3/158 204/18639 0.0147058823529412 1.73482874162323 0.249803299463208 0.446962101932104 GO:0019001 guanyl nucleotide binding 5/158 400/18639 0.0125 1.47460443037975 0.252353893417302 0.447824737088901 GO:0032561 guanyl ribonucleotide binding 5/158 400/18639 0.0125 1.47460443037975 0.252353893417302 0.447824737088901 GO:0000175 3'-5'-RNA exonuclease activity 1/158 35/18639 0.0285714285714286 3.37052441229656 0.257867617305628 0.452051329122822 GO:0034061 DNA polymerase activity 1/158 35/18639 0.0285714285714286 3.37052441229656 0.257867617305628 0.452051329122822 GO:0043015 gamma-tubulin binding 1/158 35/18639 0.0285714285714286 3.37052441229656 0.257867617305628 0.452051329122822 GO:0004518 nuclease activity 3/158 209/18639 0.0143540669856459 1.69332566168009 0.261179355760327 0.454190238184555 GO:0019208 phosphatase regulator activity 2/158 117/18639 0.0170940170940171 2.01655306718598 0.26118561041098 0.454190238184555 GO:0005484 SNAP receptor activity 1/158 36/18639 0.0277777777777778 3.27689873417722 0.264170397162956 0.455720246898644 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/158 36/18639 0.0277777777777778 3.27689873417722 0.264170397162956 0.455720246898644 GO:0030551 cyclic nucleotide binding 1/158 37/18639 0.027027027027027 3.18833390352378 0.270419984715944 0.462813649731241 GO:0043394 proteoglycan binding 1/158 37/18639 0.027027027027027 3.18833390352378 0.270419984715944 0.462813649731241 GO:0003697 single-stranded DNA binding 2/158 121/18639 0.0165289256198347 1.94989015587405 0.273751796607191 0.466050917034083 GO:0016741 transferase activity, transferring one-carbon groups 3/158 215/18639 0.013953488372093 1.64607006181925 0.274917635313399 0.466050917034083 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/158 38/18639 0.0263157894736842 3.10443037974684 0.276616826045634 0.466050917034083 GO:0043531 ADP binding 1/158 38/18639 0.0263157894736842 3.10443037974684 0.276616826045634 0.466050917034083 GO:0051020 GTPase binding 4/158 315/18639 0.0126984126984127 1.49801084990958 0.278396075790305 0.467230623322489 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/158 39/18639 0.0256410256410256 3.02482960077897 0.28276136351592 0.472489565627566 GO:0004177 aminopeptidase activity 1/158 40/18639 0.025 2.94920886075949 0.288854035804333 0.472489565627566 GO:0004532 RNA exonuclease activity 1/158 40/18639 0.025 2.94920886075949 0.288854035804333 0.472489565627566 GO:0030331 nuclear estrogen receptor binding 1/158 40/18639 0.025 2.94920886075949 0.288854035804333 0.472489565627566 GO:0032451 demethylase activity 1/158 40/18639 0.025 2.94920886075949 0.288854035804333 0.472489565627566 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/158 40/18639 0.025 2.94920886075949 0.288854035804333 0.472489565627566 GO:0004519 endonuclease activity 2/158 127/18639 0.015748031496063 1.85776936110834 0.292581786767481 0.472489565627566 GO:0042826 histone deacetylase binding 2/158 127/18639 0.015748031496063 1.85776936110834 0.292581786767481 0.472489565627566 GO:0001530 lipopolysaccharide binding 1/158 41/18639 0.024390243902439 2.87727693732634 0.294895277932561 0.472489565627566 GO:0001727 lipid kinase activity 1/158 41/18639 0.024390243902439 2.87727693732634 0.294895277932561 0.472489565627566 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/158 41/18639 0.024390243902439 2.87727693732634 0.294895277932561 0.472489565627566 GO:0031490 chromatin DNA binding 2/158 128/18639 0.015625 1.84325553797468 0.29571517848746 0.472489565627566 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/158 128/18639 0.015625 1.84325553797468 0.29571517848746 0.472489565627566 GO:0035591 signaling adaptor activity 2/158 129/18639 0.0155038759689922 1.82896673535472 0.298846628245824 0.473752116297298 GO:0061134 peptidase regulator activity 3/158 226/18639 0.0132743362831858 1.56595160748292 0.300282122397348 0.473752116297298 GO:0008307 structural constituent of muscle 1/158 42/18639 0.0238095238095238 2.80877034358047 0.300885521296721 0.473752116297298 GO:0031492 nucleosomal DNA binding 1/158 42/18639 0.0238095238095238 2.80877034358047 0.300885521296721 0.473752116297298 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/158 130/18639 0.0153846153846154 1.81489776046738 0.301975944799201 0.473752116297298 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/158 229/18639 0.0131004366812227 1.54543695760323 0.307226127230966 0.480161253499741 GO:0005085 guanyl-nucleotide exchange factor activity 3/158 230/18639 0.0130434782608696 1.53871766648321 0.309542384422012 0.480161253499741 GO:0001223 transcription coactivator binding 1/158 44/18639 0.0227272727272727 2.68109896432681 0.312714719369346 0.480161253499741 GO:0019205 nucleobase-containing compound kinase activity 1/158 44/18639 0.0227272727272727 2.68109896432681 0.312714719369346 0.480161253499741 GO:0030547 signaling receptor inhibitor activity 1/158 44/18639 0.0227272727272727 2.68109896432681 0.312714719369346 0.480161253499741 GO:0043014 alpha-tubulin binding 1/158 44/18639 0.0227272727272727 2.68109896432681 0.312714719369346 0.480161253499741 GO:0042605 peptide antigen binding 1/158 45/18639 0.0222222222222222 2.62151898734177 0.318554519011166 0.487234013835811 GO:0044325 transmembrane transporter binding 2/158 136/18639 0.0147058823529412 1.73482874162323 0.320696752755673 0.487234013835811 GO:0140789 histone phosphatase activity 2/158 136/18639 0.0147058823529412 1.73482874162323 0.320696752755673 0.487234013835811 GO:0030276 clathrin binding 1/158 46/18639 0.0217391304347826 2.56452944413869 0.324345009814449 0.491053808565232 GO:0030295 protein kinase activator activity 2/158 139/18639 0.0143884892086331 1.69738639468172 0.330013864718871 0.49627604228619 GO:0001784 phosphotyrosine residue binding 1/158 47/18639 0.0212765957446809 2.50996498788042 0.330086605492893 0.49627604228619 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/158 48/18639 0.0208333333333333 2.45767405063291 0.335779716311101 0.503088640701407 GO:0019903 protein phosphatase binding 2/158 144/18639 0.0138888888888889 1.63844936708861 0.345462987434456 0.515811977790067 GO:0005048 signal sequence binding 1/158 51/18639 0.0196078431372549 2.31310498883098 0.352572191112203 0.516714571277952 GO:0030544 Hsp70 protein binding 1/158 51/18639 0.0196078431372549 2.31310498883098 0.352572191112203 0.516714571277952 GO:0140104 molecular carrier activity 3/158 249/18639 0.0120481927710843 1.42130547506482 0.353575791604069 0.516714571277952 GO:0019209 kinase activator activity 2/158 148/18639 0.0135135135135135 1.59416695176189 0.357740002854778 0.516714571277952 GO:0005080 protein kinase C binding 1/158 52/18639 0.0192307692307692 2.26862220058423 0.358075397148585 0.516714571277952 GO:0004864 protein phosphatase inhibitor activity 1/158 53/18639 0.0188679245283019 2.22581800812037 0.363532118903065 0.516714571277952 GO:0005246 calcium channel regulator activity 1/158 53/18639 0.0188679245283019 2.22581800812037 0.363532118903065 0.516714571277952 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/158 53/18639 0.0188679245283019 2.22581800812037 0.363532118903065 0.516714571277952 GO:0016860 intramolecular oxidoreductase activity 1/158 53/18639 0.0188679245283019 2.22581800812037 0.363532118903065 0.516714571277952 GO:0038064 collagen receptor activity 1/158 53/18639 0.0188679245283019 2.22581800812037 0.363532118903065 0.516714571277952 GO:0000510 H3-H4 histone complex chaperone activity 2/158 151/18639 0.0132450331125828 1.56249476066728 0.366893887490567 0.516714571277952 GO:0140584 chromatin extrusion motor activity 2/158 151/18639 0.0132450331125828 1.56249476066728 0.366893887490567 0.516714571277952 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/158 151/18639 0.0132450331125828 1.56249476066728 0.366893887490567 0.516714571277952 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/158 151/18639 0.0132450331125828 1.56249476066728 0.366893887490567 0.516714571277952 GO:0017069 snRNA binding 1/158 54/18639 0.0185185185185185 2.18459915611814 0.368942746537484 0.516714571277952 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/158 54/18639 0.0185185185185185 2.18459915611814 0.368942746537484 0.516714571277952 GO:0051287 NAD binding 1/158 54/18639 0.0185185185185185 2.18459915611814 0.368942746537484 0.516714571277952 GO:0140463 chromatin-protein adaptor activity 1/158 54/18639 0.0185185185185185 2.18459915611814 0.368942746537484 0.516714571277952 GO:0015616 DNA translocase activity 2/158 152/18639 0.0131578947368421 1.55221518987342 0.369934219621628 0.516714571277952 GO:0140674 ATP-dependent histone chaperone activity 2/158 152/18639 0.0131578947368421 1.55221518987342 0.369934219621628 0.516714571277952 GO:0061775 cohesin loader activity 2/158 153/18639 0.0130718954248366 1.54206999255398 0.372968861075694 0.519278189214713 GO:0004386 helicase activity 2/158 155/18639 0.0129032258064516 1.52217231523071 0.379020587022444 0.525171262770964 GO:0019212 phosphatase inhibitor activity 1/158 56/18639 0.0178571428571429 2.10657775768535 0.379627263850604 0.525171262770964 GO:0140658 ATP-dependent chromatin remodeler activity 2/158 158/18639 0.0126582278481013 1.49327030924531 0.388052528584214 0.534914536548094 GO:0008408 3'-5' exonuclease activity 1/158 58/18639 0.0172413793103448 2.03393714535137 0.390132005787028 0.534914536548094 GO:0003689 DNA clamp loader activity 2/158 160/18639 0.0125 1.47460443037975 0.394042081562313 0.534914536548094 GO:0099106 ion channel regulator activity 2/158 160/18639 0.0125 1.47460443037975 0.394042081562313 0.534914536548094 GO:0015459 potassium channel regulator activity 1/158 59/18639 0.0169491525423729 1.99946363441322 0.395317902298822 0.534914536548094 GO:0036002 pre-mRNA binding 1/158 59/18639 0.0169491525423729 1.99946363441322 0.395317902298822 0.534914536548094 GO:0045309 protein phosphorylated amino acid binding 1/158 59/18639 0.0169491525423729 1.99946363441322 0.395317902298822 0.534914536548094 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/158 60/18639 0.0166666666666667 1.96613924050633 0.400459978264204 0.538506740957765 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/158 60/18639 0.0166666666666667 1.96613924050633 0.400459978264204 0.538506740957765 GO:0005096 GTPase activator activity 3/158 271/18639 0.011070110701107 1.30592274277173 0.404121738225985 0.540838574078831 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/158 61/18639 0.0163934426229508 1.93390744967836 0.405558601625755 0.540838574078831 GO:0140713 histone chaperone activity 2/158 164/18639 0.0121951219512195 1.43863846866317 0.405941193015289 0.540838574078831 GO:0005126 cytokine receptor binding 3/158 275/18639 0.0109090909090909 1.28692750287687 0.413205831976222 0.548828605048172 GO:0140098 catalytic activity, acting on RNA 4/158 387/18639 0.0103359173126615 1.21931115690315 0.416253160180339 0.551185377241855 GO:0016247 channel regulator activity 2/158 168/18639 0.0119047619047619 1.40438517179024 0.417728374148008 0.551452396360023 GO:0141108 transporter regulator activity 2/158 170/18639 0.0117647058823529 1.38786299329859 0.423578140904911 0.557475182406768 GO:0038024 cargo receptor activity 1/158 65/18639 0.0153846153846154 1.81489776046738 0.425525820974582 0.558341456006042 GO:0008235 metalloexopeptidase activity 1/158 66/18639 0.0151515151515152 1.78739930955121 0.430412593898348 0.562433621587533 GO:0031267 small GTPase binding 3/158 283/18639 0.0106007067137809 1.25054792682381 0.431242407314229 0.562433621587533 GO:0050840 extracellular matrix binding 1/158 67/18639 0.0149253731343284 1.76072170791612 0.435258058290964 0.565966183903866 GO:0003735 structural constituent of ribosome 2/158 175/18639 0.0114285714285714 1.34820976491863 0.43806928825303 0.567104431460623 GO:0030145 manganese ion binding 1/158 68/18639 0.0147058823529412 1.73482874162323 0.440062561133416 0.567104431460623 GO:0140223 general transcription initiation factor activity 1/158 68/18639 0.0147058823529412 1.73482874162323 0.440062561133416 0.567104431460623 GO:0043021 ribonucleoprotein complex binding 2/158 177/18639 0.0112994350282486 1.33297575627548 0.443810787037688 0.570237598775426 GO:0005319 lipid transporter activity 2/158 178/18639 0.0112359550561798 1.32548712843123 0.446669463035734 0.572212655309091 GO:0042379 chemokine receptor binding 1/158 72/18639 0.0138888888888889 1.63844936708861 0.458877795763436 0.5861182465061 GO:0043539 protein serine/threonine kinase activator activity 1/158 73/18639 0.0136986301369863 1.61600485521068 0.463482595045463 0.58701660167163 GO:0008237 metallopeptidase activity 2/158 184/18639 0.0108695652173913 1.28226472206935 0.463648216562811 0.58701660167163 GO:0061135 endopeptidase regulator activity 2/158 184/18639 0.0108695652173913 1.28226472206935 0.463648216562811 0.58701660167163 GO:0031491 nucleosome binding 1/158 74/18639 0.0135135135135135 1.59416695176189 0.46804845468043 0.589142386269263 GO:0035064 methylated histone binding 1/158 74/18639 0.0135135135135135 1.59416695176189 0.46804845468043 0.589142386269263 GO:0019003 GDP binding 1/158 75/18639 0.0133333333333333 1.57291139240506 0.47257570187464 0.593116750468751 GO:0140597 protein carrier chaperone 2/158 188/18639 0.0106382978723404 1.25498249394021 0.474797760864449 0.594183325012447 GO:0140034 methylation-dependent protein binding 1/158 76/18639 0.0131578947368421 1.55221518987342 0.477064661102382 0.595299706793462 GO:0019902 phosphatase binding 2/158 190/18639 0.0105263157894737 1.24177215189873 0.480320274332894 0.597639881569377 GO:0046332 SMAD binding 1/158 79/18639 0.0126582278481013 1.49327030924531 0.490305015224282 0.601793176807075 GO:0001618 virus receptor activity 1/158 81/18639 0.0123456790123457 1.4563994374121 0.498946305943972 0.601793176807075 GO:0030971 receptor tyrosine kinase binding 1/158 81/18639 0.0123456790123457 1.4563994374121 0.498946305943972 0.601793176807075 GO:0033192 calmodulin-dependent protein phosphatase activity 1/158 81/18639 0.0123456790123457 1.4563994374121 0.498946305943972 0.601793176807075 GO:0140791 histone H2AXS140 phosphatase activity 1/158 81/18639 0.0123456790123457 1.4563994374121 0.498946305943972 0.601793176807075 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/158 81/18639 0.0123456790123457 1.4563994374121 0.498946305943972 0.601793176807075 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/158 81/18639 0.0123456790123457 1.4563994374121 0.498946305943972 0.601793176807075 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/158 81/18639 0.0123456790123457 1.4563994374121 0.498946305943972 0.601793176807075 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/158 81/18639 0.0123456790123457 1.4563994374121 0.498946305943972 0.601793176807075 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/158 81/18639 0.0123456790123457 1.4563994374121 0.498946305943972 0.601793176807075 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/158 81/18639 0.0123456790123457 1.4563994374121 0.498946305943972 0.601793176807075 GO:0033549 MAP kinase phosphatase activity 1/158 82/18639 0.0121951219512195 1.43863846866317 0.50321220117303 0.601979145823591 GO:0140272 exogenous protein binding 1/158 82/18639 0.0121951219512195 1.43863846866317 0.50321220117303 0.601979145823591 GO:0001540 amyloid-beta binding 1/158 83/18639 0.0120481927710843 1.42130547506482 0.507442005139979 0.601979145823591 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/158 83/18639 0.0120481927710843 1.42130547506482 0.507442005139979 0.601979145823591 GO:0008135 translation factor activity, RNA binding 1/158 83/18639 0.0120481927710843 1.42130547506482 0.507442005139979 0.601979145823591 GO:0030165 PDZ domain binding 1/158 83/18639 0.0120481927710843 1.42130547506482 0.507442005139979 0.601979145823591 GO:0004527 exonuclease activity 1/158 84/18639 0.0119047619047619 1.40438517179024 0.51163602126349 0.602006514149705 GO:0017018 myosin phosphatase activity 1/158 84/18639 0.0119047619047619 1.40438517179024 0.51163602126349 0.602006514149705 GO:0180051 translation factor activity 1/158 84/18639 0.0119047619047619 1.40438517179024 0.51163602126349 0.602006514149705 GO:0003727 single-stranded RNA binding 1/158 89/18639 0.0112359550561798 1.32548712843123 0.532079727632824 0.620998711765533 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/158 89/18639 0.0112359550561798 1.32548712843123 0.532079727632824 0.620998711765533 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/158 89/18639 0.0112359550561798 1.32548712843123 0.532079727632824 0.620998711765533 GO:0008094 ATP-dependent activity, acting on DNA 2/158 210/18639 0.00952380952380952 1.12350813743219 0.533542758786346 0.621032297189484 GO:0140793 histone H2AXY142 phosphatase activity 1/158 90/18639 0.0111111111111111 1.31075949367089 0.536065248012016 0.622295582812876 GO:0045296 cadherin binding 3/158 334/18639 0.00898203592814371 1.05959599787766 0.540568167899723 0.625844964440054 GO:0140097 catalytic activity, acting on DNA 3/158 336/18639 0.00892857142857143 1.05328887884268 0.544614087827286 0.62884773341124 GO:0051213 dioxygenase activity 1/158 93/18639 0.010752688172043 1.26847692935892 0.547820539366585 0.629194412588147 GO:0051219 phosphoprotein binding 1/158 93/18639 0.010752688172043 1.26847692935892 0.547820539366585 0.629194412588147 GO:0004867 serine-type endopeptidase inhibitor activity 1/158 95/18639 0.0105263157894737 1.24177215189873 0.555492483141091 0.636318108994953 GO:0004725 protein tyrosine phosphatase activity 1/158 98/18639 0.0102040816326531 1.20375871867734 0.566758533551215 0.645806434283358 GO:0042626 ATPase-coupled transmembrane transporter activity 1/158 98/18639 0.0102040816326531 1.20375871867734 0.566758533551215 0.645806434283358 GO:0008238 exopeptidase activity 1/158 102/18639 0.00980392156862745 1.15655249441549 0.581339736681467 0.660682692868964 GO:0008013 beta-catenin binding 1/158 106/18639 0.00943396226415094 1.11290900406019 0.595433195701584 0.674928203504675 GO:0004843 cysteine-type deubiquitinase activity 1/158 108/18639 0.00925925925925926 1.09229957805907 0.602302109393385 0.680931627590955 GO:0004222 metalloendopeptidase activity 1/158 110/18639 0.00909090909090909 1.07243958573072 0.609055125293653 0.686773097010812 GO:0005543 phospholipid binding 4/158 497/18639 0.00804828973843058 0.949443496421567 0.610969198812474 0.687141982041042 GO:0043022 ribosome binding 1/158 112/18639 0.00892857142857143 1.05328887884268 0.615694186675909 0.69066213168567 GO:0042393 histone binding 2/158 247/18639 0.00809716599190283 0.955209347614411 0.621859509666094 0.695775627094105 GO:0017124 SH3 domain binding 1/158 115/18639 0.00869565217391304 1.02581177765548 0.625443285391355 0.696187513044876 GO:0101005 deubiquitinase activity 1/158 115/18639 0.00869565217391304 1.02581177765548 0.625443285391355 0.696187513044876 GO:0022853 active monoatomic ion transmembrane transporter activity 1/158 118/18639 0.00847457627118644 0.999731817206608 0.634946593991136 0.704953526149133 GO:0019887 protein kinase regulator activity 2/158 255/18639 0.00784313725490196 0.92524199553239 0.639184580611248 0.707843793873838 GO:0032182 ubiquitin-like protein binding 1/158 120/18639 0.00833333333333333 0.983069620253164 0.641148630469558 0.708207543350303 GO:0004540 RNA nuclease activity 1/158 121/18639 0.00826446280991736 0.974945077937023 0.644210270751745 0.709778746146324 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/158 122/18639 0.00819672131147541 0.966953724839178 0.647245953720814 0.711313446601808 GO:0005267 potassium channel activity 1/158 124/18639 0.00806451612903226 0.951357697019191 0.653240320618331 0.714921534303545 GO:0003730 mRNA 3'-UTR binding 2/158 262/18639 0.00763358778625954 0.900521789544883 0.653831241533958 0.714921534303545 GO:0019783 ubiquitin-like protein peptidase activity 1/158 127/18639 0.0078740157480315 0.928884680554171 0.662042598998389 0.722076688580107 GO:0005262 calcium channel activity 1/158 131/18639 0.00763358778625954 0.900521789544883 0.673434506810005 0.732010690726204 GO:0005179 hormone activity 1/158 132/18639 0.00757575757575758 0.893699654775604 0.676222347091182 0.732010690726204 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/158 132/18639 0.00757575757575758 0.893699654775604 0.676222347091182 0.732010690726204 GO:0016779 nucleotidyltransferase activity 1/158 136/18639 0.00735294117647059 0.867414370811616 0.687139193303599 0.737742557169792 GO:0019838 growth factor binding 1/158 136/18639 0.00735294117647059 0.867414370811616 0.687139193303599 0.737742557169792 GO:0099094 ligand-gated monoatomic cation channel activity 1/158 136/18639 0.00735294117647059 0.867414370811616 0.687139193303599 0.737742557169792 GO:0004857 enzyme inhibitor activity 3/158 416/18639 0.00721153846153846 0.850733325219085 0.688332547567196 0.737742557169792 GO:0070851 growth factor receptor binding 1/158 139/18639 0.00719424460431655 0.848693197340862 0.695086076678781 0.741311012812591 GO:0140101 catalytic activity, acting on a tRNA 1/158 139/18639 0.00719424460431655 0.848693197340862 0.695086076678781 0.741311012812591 GO:0019207 kinase regulator activity 2/158 287/18639 0.00696864111498258 0.822079124950382 0.702311629362318 0.747176745734358 GO:0015085 calcium ion transmembrane transporter activity 1/158 147/18639 0.00680272108843537 0.802505812451563 0.715310612512358 0.759140919651596 GO:0001664 G protein-coupled receptor binding 2/158 297/18639 0.00673400673400673 0.79439969313387 0.72007635110151 0.762330220114801 GO:0005506 iron ion binding 1/158 154/18639 0.00649350649350649 0.766028275521946 0.731910118670385 0.772968491181163 GO:0015079 potassium ion transmembrane transporter activity 1/158 160/18639 0.00625 0.737302215189873 0.745370373340322 0.785268544176056 GO:0004866 endopeptidase inhibitor activity 1/158 161/18639 0.0062111801242236 0.73272269832534 0.747547519344555 0.785650669602409 GO:0015399 primary active transmembrane transporter activity 1/158 166/18639 0.00602409638554217 0.710652737532408 0.758158878605231 0.794873594276186 GO:0030414 peptidase inhibitor activity 1/158 169/18639 0.00591715976331361 0.698037600179762 0.764311703323159 0.799388810480502 GO:0003823 antigen binding 1/158 174/18639 0.00574712643678161 0.677979048450458 0.774222630014844 0.807803370593801 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/158 181/18639 0.00552486187845304 0.651758864256242 0.787405887667467 0.818217839177775 GO:0005261 monoatomic cation channel activity 2/158 341/18639 0.00586510263929619 0.691896506923048 0.787983461748573 0.818217839177775 GO:0015276 ligand-gated monoatomic ion channel activity 1/158 186/18639 0.00537634408602151 0.634238464679461 0.796351394088089 0.824580411720086 GO:0008234 cysteine-type peptidase activity 1/158 187/18639 0.0053475935828877 0.630846815135721 0.798095093201192 0.824580411720086 GO:0022834 ligand-gated channel activity 1/158 188/18639 0.00531914893617021 0.627491246970105 0.799823955940961 0.824580411720086 GO:0008236 serine-type peptidase activity 1/158 194/18639 0.00515463917525773 0.608084301187524 0.809892519844234 0.832977342262597 GO:0017171 serine hydrolase activity 1/158 198/18639 0.00505050505050505 0.595799769850403 0.816323664633835 0.837602243569788 GO:0005516 calmodulin binding 1/158 207/18639 0.00483091787439614 0.56989543203082 0.830014138859478 0.849636222520458 GO:0051015 actin filament binding 1/158 209/18639 0.00478468899521531 0.564441887226697 0.83291598080604 0.850595801153338 GO:0004175 endopeptidase activity 2/158 405/18639 0.00493827160493827 0.582559774964838 0.860952704679472 0.877158873238144 GO:0033218 amide binding 1/158 247/18639 0.00404858299595142 0.477604673807206 0.879579611930655 0.894032798042191 GO:0005216 monoatomic ion channel activity 2/158 448/18639 0.00446428571428571 0.526644439421338 0.896290768506899 0.908200203236663 GO:0046873 metal ion transmembrane transporter activity 2/158 450/18639 0.00444444444444444 0.524303797468354 0.897712902968341 0.908200203236663 GO:1901681 sulfur compound binding 1/158 275/18639 0.00363636363636364 0.42897583429229 0.905440235189039 0.913882568384275 GO:0022836 gated channel activity 1/158 318/18639 0.00314465408805031 0.370969668020062 0.934814245010278 0.941336204859187 GO:0004984 olfactory receptor activity 1/158 419/18639 0.00238663484486874 0.281547385275369 0.972886427644336 0.977400981832941 GO:0003779 actin binding 1/158 443/18639 0.00225733634311512 0.266294253793182 0.978003767035489 0.980267664644367 GO:0022804 active transmembrane transporter activity 1/158 457/18639 0.00218818380743982 0.258136442954879 0.980532793372798 0.980532793372798