ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0140662	ATP-dependent protein folding chaperone	9/484	40/18639	0.225	8.66482438016529	6.65901513589309e-07	0.000522732688167608
GO:0051082	unfolded protein binding	14/484	121/18639	0.115702479338843	4.45574072809234	3.14238876579062e-06	0.000924931399477643
GO:0044183	protein folding chaperone	11/484	75/18639	0.146666666666667	5.64818181818182	3.53476967953239e-06	0.000924931399477643
GO:0031072	heat shock protein binding	14/484	131/18639	0.106870229007634	4.11560784808529	8.02277831137033e-06	0.00157447024360643
GO:0051879	Hsp90 protein binding	7/484	42/18639	0.166666666666667	6.41838842975207	9.35698381257051e-05	0.0146904645857357
GO:0017124	SH3 domain binding	11/484	115/18639	0.0956521739130435	3.68359683794466	0.000202462823276087	0.0253666058043999
GO:0016779	nucleotidyltransferase activity	12/484	136/18639	0.0882352941176471	3.39797034516286	0.000226199032650699	0.0253666058043999
GO:0002039	p53 binding	8/484	69/18639	0.115942028985507	4.46496586417535	0.000406824134939697	0.0399196182409577
GO:0042169	SH2 domain binding	6/484	41/18639	0.146341463414634	5.63565813344084	0.000617817874372278	0.0538874479313598
GO:0141052	histone H3 demethylase activity	5/484	28/18639	0.178571428571429	6.87684474616293	0.000693354759807476	0.0544283486448869
GO:0032452	histone demethylase activity	5/484	30/18639	0.166666666666667	6.41838842975207	0.000963360196493091	0.0619224888243042
GO:0070566	adenylyltransferase activity	5/484	30/18639	0.166666666666667	6.41838842975207	0.000963360196493091	0.0619224888243042
GO:0140303	intramembrane lipid transporter activity	6/484	45/18639	0.133333333333333	5.13471074380165	0.00102546796779102	0.0619224888243042
GO:0140457	protein demethylase activity	5/484	31/18639	0.161290322580645	6.21134364169555	0.00112439502387516	0.0630464352672856
GO:0045296	cadherin binding	19/484	334/18639	0.0568862275449102	2.19070742811897	0.00123739157530689	0.0647568257743938
GO:0019783	ubiquitin-like protein peptidase activity	10/484	127/18639	0.078740157480315	3.03230949437105	0.00177141402500587	0.0844869790202771
GO:0005154	epidermal growth factor receptor binding	5/484	35/18639	0.142857142857143	5.50147579693034	0.00197296210071892	0.0844869790202771
GO:0044389	ubiquitin-like protein ligase binding	18/484	322/18639	0.0559006211180124	2.15275139879883	0.00199337061507121	0.0844869790202771
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	19/484	349/18639	0.0544412607449857	2.09655094840039	0.00204490777246531	0.0844869790202771
GO:0140297	DNA-binding transcription factor binding	24/484	488/18639	0.0491803278688525	1.89395068418913	0.00222098647789093	0.087173719257219
GO:0140537	transcription regulator activator activity	3/484	11/18639	0.272727272727273	10.5028174305034	0.00245764450502294	0.0918690922115719
GO:0003712	transcription coregulator activity	24/484	495/18639	0.0484848484848485	1.8671675432006	0.00266765492907118	0.0951867781509488
GO:0016922	nuclear receptor binding	10/484	137/18639	0.072992700729927	2.81097303492791	0.00309119201232669	0.0997808104201743
GO:0035259	nuclear glucocorticoid receptor binding	3/484	12/18639	0.25	9.6275826446281	0.00321408370820975	0.0997808104201743
GO:1990817	poly(A) RNA polymerase activity	3/484	12/18639	0.25	9.6275826446281	0.00321408370820975	0.0997808104201743
GO:0003725	double-stranded RNA binding	7/484	75/18639	0.0933333333333333	3.59429752066116	0.00330484212856628	0.0997808104201743
GO:0032451	demethylase activity	5/484	40/18639	0.125	4.81379132231405	0.00359657391432761	0.102012535594053
GO:0008234	cysteine-type peptidase activity	12/484	187/18639	0.0641711229946524	2.47125116011844	0.00363866368997895	0.102012535594053
GO:0032182	ubiquitin-like protein binding	9/484	120/18639	0.075	2.88827479338843	0.00409677198695569	0.103781324115867
GO:0032396	inhibitory MHC class I receptor activity	3/484	13/18639	0.230769230769231	8.88699936427209	0.00409837076126355	0.103781324115867
GO:0046975	histone H3K36 methyltransferase activity	3/484	13/18639	0.230769230769231	8.88699936427209	0.00409837076126355	0.103781324115867
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/484	27/18639	0.148148148148148	5.70523415977961	0.00490590841236955	0.120348065740941
GO:1901474	azole transmembrane transporter activity	3/484	14/18639	0.214285714285714	8.25221369539551	0.00511644935867674	0.121709477168523
GO:0097718	disordered domain specific binding	4/484	28/18639	0.142857142857143	5.50147579693034	0.00560800068779657	0.129294117381768
GO:0031625	ubiquitin protein ligase binding	16/484	302/18639	0.0529801324503311	2.04028241475562	0.00577466142543715	0.129294117381768
GO:0042826	histone deacetylase binding	9/484	127/18639	0.0708661417322835	2.72907854493395	0.0059294117525397	0.129294117381768
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	9/484	128/18639	0.0703125	2.70775761880165	0.00623581316243769	0.131674728670219
GO:0106222	lncRNA binding	4/484	29/18639	0.137931034482759	5.31176973496723	0.00637406329868578	0.131674728670219
GO:0016887	ATP hydrolysis activity	20/484	417/18639	0.0479616306954436	1.84701825316606	0.0065494749512573	0.131829175300948
GO:0004843	cysteine-type deubiquitinase activity	8/484	108/18639	0.0740740740740741	2.85261707988981	0.00714283682788828	0.139186680513333
GO:0003713	transcription coactivator activity	14/484	256/18639	0.0546875	2.1060337035124	0.0072696228038811	0.139186680513333
GO:0140327	flippase activity	3/484	16/18639	0.1875	7.22068698347107	0.00757414868076617	0.141564445580987
GO:0051087	protein-folding chaperone binding	9/484	134/18639	0.0671641791044776	2.58651474034785	0.00833767407490042	0.149256255058232
GO:0005548	phospholipid transporter activity	6/484	68/18639	0.0882352941176471	3.39797034516286	0.00836595569753148	0.149256255058232
GO:0061659	ubiquitin-like protein ligase activity	18/484	372/18639	0.0483870967741935	1.86340309250866	0.00881698099333611	0.153807335105974
GO:0101005	deubiquitinase activity	8/484	115/18639	0.0695652173913043	2.67897951850521	0.0102720788434844	0.1736956723974
GO:0004706	JUN kinase kinase kinase activity	3/484	18/18639	0.166666666666667	6.41838842975207	0.0106208818790767	0.1736956723974
GO:0032393	MHC class I receptor activity	3/484	18/18639	0.166666666666667	6.41838842975207	0.0106208818790767	0.1736956723974
GO:0019902	phosphatase binding	11/484	190/18639	0.0578947368421053	2.22954545454545	0.0110218127233956	0.175981931260707
GO:0061630	ubiquitin protein ligase activity	17/484	353/18639	0.0481586402266289	1.85460515533912	0.0112090402076883	0.175981931260707
GO:0016791	phosphatase activity	14/484	273/18639	0.0512820512820513	1.97488874761602	0.0123408981033648	0.189953039434145
GO:0019903	protein phosphatase binding	9/484	144/18639	0.0625	2.40689566115702	0.0129833058275515	0.195997982204383
GO:0004725	protein tyrosine phosphatase activity	7/484	98/18639	0.0714285714285714	2.75073789846517	0.0138995826090498	0.205871176379322
GO:0000339	RNA cap binding	3/484	20/18639	0.15	5.77654958677686	0.0142805988422799	0.207597594281291
GO:0043130	ubiquitin binding	7/484	100/18639	0.07	2.69572314049587	0.015395890929135	0.218293474596351
GO:0004721	phosphoprotein phosphatase activity	10/484	175/18639	0.0571428571428571	2.20059031877214	0.0162685391330225	0.218293474596351
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/484	21/18639	0.142857142857143	5.50147579693034	0.0163454303186455	0.218293474596351
GO:0019200	carbohydrate kinase activity	3/484	21/18639	0.142857142857143	5.50147579693034	0.0163454303186455	0.218293474596351
GO:0031267	small GTPase binding	14/484	283/18639	0.049469964664311	1.90510469292994	0.0164067707021461	0.218293474596351
GO:0043021	ribonucleoprotein complex binding	10/484	177/18639	0.0564971751412429	2.17572489144138	0.0174756123273918	0.228639261283376
GO:0003714	transcription corepressor activity	11/484	204/18639	0.053921568627451	2.07653743315508	0.017888878828221	0.229862063567966
GO:0051020	GTPase binding	15/484	315/18639	0.0476190476190476	1.83382526564345	0.0181547107531387	0.229862063567966
GO:0061133	endopeptidase activator activity	3/484	22/18639	0.136363636363636	5.25140871525169	0.0185686518140396	0.231371296413034
GO:0005543	phospholipid binding	21/484	497/18639	0.0422535211267606	1.62719706669771	0.020336504058673	0.248146990344879
GO:0005525	GTP binding	17/484	378/18639	0.044973544973545	1.73194608421881	0.0205472030221874	0.248146990344879
GO:0035035	histone acetyltransferase binding	3/484	24/18639	0.125	4.81379132231405	0.0234928435930717	0.277217994596823
GO:0048156	tau protein binding	4/484	43/18639	0.0930232558139535	3.58235633288487	0.0249518871694426	0.277217994596823
GO:0140789	histone phosphatase activity	8/484	136/18639	0.0588235294117647	2.26531356344191	0.0256947876695814	0.277217994596823
GO:0019787	ubiquitin-like protein transferase activity	20/484	479/18639	0.0417536534446764	1.60794699701513	0.0258804075634816	0.277217994596823
GO:0004842	ubiquitin-protein transferase activity	19/484	449/18639	0.0423162583518931	1.62961309797714	0.0260978164558921	0.277217994596823
GO:0004709	MAP kinase kinase kinase activity	3/484	25/18639	0.12	4.62123966942149	0.0261941017354154	0.277217994596823
GO:0005528	FK506 binding	2/484	10/18639	0.2	7.70206611570248	0.0263766458804801	0.277217994596823
GO:0050308	sugar-phosphatase activity	2/484	10/18639	0.2	7.70206611570248	0.0263766458804801	0.277217994596823
GO:0071723	lipopeptide binding	2/484	10/18639	0.2	7.70206611570248	0.0263766458804801	0.277217994596823
GO:0003924	GTPase activity	15/484	331/18639	0.0453172205438066	1.74518114404135	0.0268102269863694	0.277217994596823
GO:0043022	ribosome binding	7/484	112/18639	0.0625	2.40689566115702	0.0268389396042784	0.277217994596823
GO:0003727	single-stranded RNA binding	6/484	89/18639	0.0674157303370786	2.59620206147275	0.0283256801496031	0.278512912873922
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	6/484	89/18639	0.0674157303370786	2.59620206147275	0.0283256801496031	0.278512912873922
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	6/484	89/18639	0.0674157303370786	2.59620206147275	0.0283256801496031	0.278512912873922
GO:0042578	phosphoric ester hydrolase activity	16/484	363/18639	0.0440771349862259	1.69742503927327	0.0283834815667691	0.278512912873922
GO:0050681	nuclear androgen receptor binding	3/484	26/18639	0.115384615384615	4.44349968213605	0.0290543795239382	0.281576394151746
GO:0140793	histone H2AXY142 phosphatase activity	6/484	90/18639	0.0666666666666667	2.56735537190083	0.0297101674822557	0.28289052420353
GO:0042054	histone methyltransferase activity	5/484	67/18639	0.0746268656716418	2.87390526705316	0.029967944944014	0.28289052420353
GO:1990841	promoter-specific chromatin binding	5/484	68/18639	0.0735294117647059	2.83164195430238	0.0316823885350046	0.28289052420353
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/484	11/18639	0.181818181818182	7.00187828700225	0.0316919795194706	0.28289052420353
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/484	11/18639	0.181818181818182	7.00187828700225	0.0316919795194706	0.28289052420353
GO:0019203	carbohydrate phosphatase activity	2/484	11/18639	0.181818181818182	7.00187828700225	0.0316919795194706	0.28289052420353
GO:0001671	ATPase activator activity	3/484	27/18639	0.111111111111111	4.27892561983471	0.0320729384128842	0.28289052420353
GO:0008266	poly(U) RNA binding	3/484	27/18639	0.111111111111111	4.27892561983471	0.0320729384128842	0.28289052420353
GO:0019001	guanyl nucleotide binding	17/484	400/18639	0.0425	1.63668904958678	0.0328926995548833	0.283744715940477
GO:0032561	guanyl ribonucleotide binding	17/484	400/18639	0.0425	1.63668904958678	0.0328926995548833	0.283744715940477
GO:0140938	histone H3 methyltransferase activity	4/484	47/18639	0.0851063829787234	3.27747494285212	0.033284933384403	0.28400731202996
GO:0004674	protein serine/threonine kinase activity	18/484	433/18639	0.0415704387990762	1.60089134044624	0.0345896307022457	0.291040863695811
GO:0051019	mitogen-activated protein kinase binding	3/484	28/18639	0.107142857142857	4.12610684769776	0.0352487309398948	0.291040863695811
GO:0016755	aminoacyltransferase activity	20/484	496/18639	0.0403225806451613	1.55283591042389	0.0354075737595699	0.291040863695811
GO:0038187	pattern recognition receptor activity	4/484	48/18639	0.0833333333333333	3.20919421487603	0.0355922584901883	0.291040863695811
GO:0005095	GTPase inhibitor activity	2/484	12/18639	0.166666666666667	6.41838842975207	0.0373875586817228	0.293492335651524
GO:0005527	macrolide binding	2/484	12/18639	0.166666666666667	6.41838842975207	0.0373875586817228	0.293492335651524
GO:0097677	STAT family protein binding	2/484	12/18639	0.166666666666667	6.41838842975207	0.0373875586817228	0.293492335651524
GO:1990459	transferrin receptor binding	2/484	12/18639	0.166666666666667	6.41838842975207	0.0373875586817228	0.293492335651524
GO:0060590	ATPase regulator activity	4/484	49/18639	0.0816326530612245	3.14370045538877	0.0379898610572156	0.295267731979349
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/484	29/18639	0.103448275862069	3.98382730122542	0.0385804233600343	0.296917964094381
GO:0043539	protein serine/threonine kinase activator activity	5/484	73/18639	0.0684931506849315	2.63769387524058	0.0411653774133497	0.312848702461883
GO:0008187	poly-pyrimidine tract binding	3/484	30/18639	0.1	3.85103305785124	0.0420664171599757	0.312848702461883
GO:0031624	ubiquitin conjugating enzyme binding	3/484	30/18639	0.1	3.85103305785124	0.0420664171599757	0.312848702461883
GO:0008035	high-density lipoprotein particle binding	2/484	13/18639	0.153846153846154	5.92466624284806	0.0434401383036245	0.312848702461883
GO:0043560	insulin receptor substrate binding	2/484	13/18639	0.153846153846154	5.92466624284806	0.0434401383036245	0.312848702461883
GO:0089720	caspase binding	2/484	13/18639	0.153846153846154	5.92466624284806	0.0434401383036245	0.312848702461883
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/484	13/18639	0.153846153846154	5.92466624284806	0.0434401383036245	0.312848702461883
GO:0019003	GDP binding	5/484	75/18639	0.0666666666666667	2.56735537190083	0.0453900101626774	0.323919617979107
GO:0031490	chromatin DNA binding	7/484	128/18639	0.0546875	2.1060337035124	0.0495763141328344	0.346146234855244
GO:0032454	histone H3K9 demethylase activity	2/484	14/18639	0.142857142857143	5.50147579693034	0.0498274197944491	0.346146234855244
GO:0044548	S100 protein binding	2/484	14/18639	0.142857142857143	5.50147579693034	0.0498274197944491	0.346146234855244
GO:0106310	protein serine kinase activity	15/484	361/18639	0.0415512465373961	1.60015224010439	0.0507528658132437	0.349482453187687
GO:0035591	signaling adaptor activity	7/484	129/18639	0.0542635658914729	2.08970786084951	0.0513067501066904	0.350224337684799
GO:0140416	transcription regulator inhibitor activity	3/484	33/18639	0.0909090909090909	3.50093914350113	0.0534306722861	0.355426340902378
GO:0098632	cell-cell adhesion mediator activity	4/484	55/18639	0.0727272727272727	2.8007513148009	0.0542724549083502	0.355426340902378
GO:0004089	carbonate dehydratase activity	2/484	15/18639	0.133333333333333	5.13471074380165	0.0565280177220998	0.355426340902378
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/484	15/18639	0.133333333333333	5.13471074380165	0.0565280177220998	0.355426340902378
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/484	15/18639	0.133333333333333	5.13471074380165	0.0565280177220998	0.355426340902378
GO:0140776	protein-containing complex destabilizing activity	2/484	15/18639	0.133333333333333	5.13471074380165	0.0565280177220998	0.355426340902378
GO:0033192	calmodulin-dependent protein phosphatase activity	5/484	81/18639	0.0617283950617284	2.37718089990817	0.0595623426360083	0.355426340902378
GO:0140791	histone H2AXS140 phosphatase activity	5/484	81/18639	0.0617283950617284	2.37718089990817	0.0595623426360083	0.355426340902378
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	5/484	81/18639	0.0617283950617284	2.37718089990817	0.0595623426360083	0.355426340902378
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	5/484	81/18639	0.0617283950617284	2.37718089990817	0.0595623426360083	0.355426340902378
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	5/484	81/18639	0.0617283950617284	2.37718089990817	0.0595623426360083	0.355426340902378
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	5/484	81/18639	0.0617283950617284	2.37718089990817	0.0595623426360083	0.355426340902378
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	5/484	81/18639	0.0617283950617284	2.37718089990817	0.0595623426360083	0.355426340902378
GO:1990439	MAP kinase serine/threonine phosphatase activity	5/484	81/18639	0.0617283950617284	2.37718089990817	0.0595623426360083	0.355426340902378
GO:0001217	DNA-binding transcription repressor activity	12/484	278/18639	0.0431654676258993	1.66231642784946	0.0599134154948813	0.355426340902378
GO:0016504	peptidase activator activity	4/484	57/18639	0.0701754385964912	2.70247933884298	0.0604174529647273	0.355426340902378
GO:0000175	3'-5'-RNA exonuclease activity	3/484	35/18639	0.0857142857142857	3.30088547815821	0.0617389158372007	0.355426340902378
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	5/484	82/18639	0.0609756097560976	2.34819088893368	0.0621432327132728	0.355426340902378
GO:0033549	MAP kinase phosphatase activity	5/484	82/18639	0.0609756097560976	2.34819088893368	0.0621432327132728	0.355426340902378
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/484	16/18639	0.125	4.81379132231405	0.0635214275851475	0.355426340902378
GO:0005521	lamin binding	2/484	16/18639	0.125	4.81379132231405	0.0635214275851475	0.355426340902378
GO:0034450	ubiquitin-ubiquitin ligase activity	2/484	16/18639	0.125	4.81379132231405	0.0635214275851475	0.355426340902378
GO:0043023	ribosomal large subunit binding	2/484	16/18639	0.125	4.81379132231405	0.0635214275851475	0.355426340902378
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/484	16/18639	0.125	4.81379132231405	0.0635214275851475	0.355426340902378
GO:0140328	floppase activity	2/484	16/18639	0.125	4.81379132231405	0.0635214275851475	0.355426340902378
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	5/484	83/18639	0.0602409638554217	2.31989943244051	0.0647864409068609	0.355426340902378
GO:0005484	SNAP receptor activity	3/484	36/18639	0.0833333333333333	3.20919421487603	0.0661047716837544	0.355426340902378
GO:0044390	ubiquitin-like protein conjugating enzyme binding	3/484	36/18639	0.0833333333333333	3.20919421487603	0.0661047716837544	0.355426340902378
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	3/484	36/18639	0.0833333333333333	3.20919421487603	0.0661047716837544	0.355426340902378
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	3/484	36/18639	0.0833333333333333	3.20919421487603	0.0661047716837544	0.355426340902378
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	3/484	36/18639	0.0833333333333333	3.20919421487603	0.0661047716837544	0.355426340902378
GO:0017018	myosin phosphatase activity	5/484	84/18639	0.0595238095238095	2.29228158205431	0.0674917965629427	0.356208819168919
GO:0035091	phosphatidylinositol binding	12/484	284/18639	0.0422535211267606	1.62719706669771	0.0679818584794088	0.356208819168919
GO:1902936	phosphatidylinositol bisphosphate binding	6/484	111/18639	0.0540540540540541	2.0816394907304	0.0693496025670289	0.356208819168919
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	4/484	60/18639	0.0666666666666667	2.56735537190083	0.0702943973197211	0.356208819168919
GO:0098531	ligand-modulated transcription factor activity	4/484	60/18639	0.0666666666666667	2.56735537190083	0.0702943973197211	0.356208819168919
GO:0070851	growth factor receptor binding	7/484	139/18639	0.0503597122302158	1.93936916582437	0.0706994081720387	0.356208819168919
GO:0031489	myosin V binding	2/484	17/18639	0.117647058823529	4.53062712688381	0.0707879946373903	0.356208819168919
GO:0032183	SUMO binding	2/484	17/18639	0.117647058823529	4.53062712688381	0.0707879946373903	0.356208819168919
GO:0046965	nuclear retinoid X receptor binding	2/484	17/18639	0.117647058823529	4.53062712688381	0.0707879946373903	0.356208819168919
GO:0051787	misfolded protein binding	2/484	17/18639	0.117647058823529	4.53062712688381	0.0707879946373903	0.356208819168919
GO:0016836	hydro-lyase activity	4/484	61/18639	0.0655737704918033	2.52526757891885	0.0737596855701959	0.3664642605861
GO:0019905	syntaxin binding	4/484	61/18639	0.0655737704918033	2.52526757891885	0.0737596855701959	0.3664642605861
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	3/484	38/18639	0.0789473684210526	3.04028925619835	0.075245294654669	0.371494064804498
GO:0000287	magnesium ion binding	10/484	230/18639	0.0434782608695652	1.67436219906576	0.0780675312517534	0.37713174067338
GO:0017128	phospholipid scramblase activity	2/484	18/18639	0.111111111111111	4.27892561983471	0.0783088837321794	0.37713174067338
GO:0034185	apolipoprotein binding	2/484	18/18639	0.111111111111111	4.27892561983471	0.0783088837321794	0.37713174067338
GO:0098641	cadherin binding involved in cell-cell adhesion	2/484	18/18639	0.111111111111111	4.27892561983471	0.0783088837321794	0.37713174067338
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3/484	39/18639	0.0769230769230769	2.96233312142403	0.0800137235621295	0.382992518269949
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	18/484	484/18639	0.0371900826446281	1.43220237688682	0.0818392944898414	0.388286490640642
GO:1990782	protein tyrosine kinase binding	6/484	117/18639	0.0512820512820513	1.97488874761602	0.0844966982679974	0.388286490640642
GO:0004177	aminopeptidase activity	3/484	40/18639	0.075	2.88827479338843	0.0849099272407068	0.388286490640642
GO:0004532	RNA exonuclease activity	3/484	40/18639	0.075	2.88827479338843	0.0849099272407068	0.388286490640642
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	3/484	40/18639	0.075	2.88827479338843	0.0849099272407068	0.388286490640642
GO:0061791	GTPase motor activity	3/484	40/18639	0.075	2.88827479338843	0.0849099272407068	0.388286490640642
GO:1990606	membrane scission GTPase motor activity	3/484	40/18639	0.075	2.88827479338843	0.0849099272407068	0.388286490640642
GO:0042800	histone H3K4 methyltransferase activity	2/484	19/18639	0.105263157894737	4.05371900826446	0.0860660501547411	0.388286490640642
GO:0042834	peptidoglycan binding	2/484	19/18639	0.105263157894737	4.05371900826446	0.0860660501547411	0.388286490640642
GO:0046624	sphingolipid transporter activity	2/484	19/18639	0.105263157894737	4.05371900826446	0.0860660501547411	0.388286490640642
GO:0030695	GTPase regulator activity	18/484	489/18639	0.0368098159509202	1.41755818080414	0.0880479349013328	0.39455968761201
GO:0019843	rRNA binding	4/484	65/18639	0.0615384615384615	2.36986649713922	0.0884617898340302	0.39455968761201
GO:0060589	nucleoside-triphosphatase regulator activity	18/484	490/18639	0.036734693877551	1.41466520492495	0.0893253444266222	0.394876218162746
GO:0001530	lipopolysaccharide binding	3/484	41/18639	0.0731707317073171	2.81782906672042	0.0899305377573141	0.394876218162746
GO:0001216	DNA-binding transcription activator activity	18/484	491/18639	0.0366598778004073	1.41178401306155	0.0906146870378831	0.394876218162746
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	11/484	268/18639	0.041044776119403	1.58064789687924	0.091323311571471	0.394876218162746
GO:0001614	purinergic nucleotide receptor activity	2/484	20/18639	0.1	3.85103305785124	0.0940422114116813	0.394876218162746
GO:0016502	nucleotide receptor activity	2/484	20/18639	0.1	3.85103305785124	0.0940422114116813	0.394876218162746
GO:0030742	GTP-dependent protein binding	2/484	20/18639	0.1	3.85103305785124	0.0940422114116813	0.394876218162746
GO:0043024	ribosomal small subunit binding	2/484	20/18639	0.1	3.85103305785124	0.0940422114116813	0.394876218162746
GO:0051213	dioxygenase activity	5/484	93/18639	0.0537634408602151	2.07044788056518	0.0945892310409291	0.394876218162746
GO:0051219	phosphoprotein binding	5/484	93/18639	0.0537634408602151	2.07044788056518	0.0945892310409291	0.394876218162746
GO:0016859	cis-trans isomerase activity	3/484	42/18639	0.0714285714285714	2.75073789846517	0.0950721085767632	0.394876218162746
GO:0035198	miRNA binding	3/484	42/18639	0.0714285714285714	2.75073789846517	0.0950721085767632	0.394876218162746
GO:0048487	beta-tubulin binding	3/484	42/18639	0.0714285714285714	2.75073789846517	0.0950721085767632	0.394876218162746
GO:0030145	manganese ion binding	4/484	68/18639	0.0588235294117647	2.26531356344191	0.100341389657329	0.41362548277843
GO:0008276	protein methyltransferase activity	5/484	95/18639	0.0526315789473684	2.02685950413223	0.101265048362871	0.41362548277843
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/484	21/18639	0.0952380952380952	3.66765053128689	0.10222081994779	0.41362548277843
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/484	21/18639	0.0952380952380952	3.66765053128689	0.10222081994779	0.41362548277843
GO:0070182	DNA polymerase binding	2/484	21/18639	0.0952380952380952	3.66765053128689	0.10222081994779	0.41362548277843
GO:0016279	protein-lysine N-methyltransferase activity	4/484	69/18639	0.0579710144927536	2.23248293208768	0.104457352061256	0.419079049726293
GO:0001046	core promoter sequence-specific DNA binding	3/484	44/18639	0.0681818181818182	2.62570435762585	0.105704015090199	0.419079049726293
GO:0001223	transcription coactivator binding	3/484	44/18639	0.0681818181818182	2.62570435762585	0.105704015090199	0.419079049726293
GO:0043014	alpha-tubulin binding	3/484	44/18639	0.0681818181818182	2.62570435762585	0.105704015090199	0.419079049726293
GO:0016278	lysine N-methyltransferase activity	4/484	70/18639	0.0571428571428571	2.20059031877214	0.108649177775756	0.428590977658133
GO:1901981	phosphatidylinositol phosphate binding	8/484	185/18639	0.0432432432432432	1.66531159258432	0.109864849436025	0.431219534036397
GO:0033691	sialic acid binding	2/484	22/18639	0.0909090909090909	3.50093914350113	0.110586036761165	0.431890740584651
GO:0140375	immune receptor activity	7/484	156/18639	0.0448717948717949	1.72802765416402	0.112405776711962	0.436824429301438
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	2/484	23/18639	0.0869565217391304	3.34872439813151	0.119122705888543	0.451745527161867
GO:0005158	insulin receptor binding	2/484	23/18639	0.0869565217391304	3.34872439813151	0.119122705888543	0.451745527161867
GO:0016493	C-C chemokine receptor activity	2/484	23/18639	0.0869565217391304	3.34872439813151	0.119122705888543	0.451745527161867
GO:0031681	G-protein beta-subunit binding	2/484	23/18639	0.0869565217391304	3.34872439813151	0.119122705888543	0.451745527161867
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	2/484	23/18639	0.0869565217391304	3.34872439813151	0.119122705888543	0.451745527161867
GO:0015295	solute:proton symporter activity	2/484	24/18639	0.0833333333333333	3.20919421487603	0.127816329733586	0.477180823334546
GO:0019957	C-C chemokine binding	2/484	24/18639	0.0833333333333333	3.20919421487603	0.127816329733586	0.477180823334546
GO:0070300	phosphatidic acid binding	2/484	24/18639	0.0833333333333333	3.20919421487603	0.127816329733586	0.477180823334546
GO:0140693	molecular condensate scaffold activity	3/484	48/18639	0.0625	2.40689566115702	0.128261342323044	0.477180823334546
GO:0004722	protein serine/threonine phosphatase activity	5/484	103/18639	0.0485436893203883	1.86943352322876	0.130202681001634	0.482118417859823
GO:0035254	glutamate receptor binding	3/484	49/18639	0.0612244897959184	2.35777534154158	0.13414861284038	0.492076332528325
GO:0098631	cell adhesion mediator activity	4/484	76/18639	0.0526315789473684	2.02685950413223	0.135313352557906	0.492076332528325
GO:0017056	structural constituent of nuclear pore	2/484	25/18639	0.08	3.08082644628099	0.136653045211688	0.492076332528325
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/484	25/18639	0.08	3.08082644628099	0.136653045211688	0.492076332528325
GO:0019707	protein-cysteine S-acyltransferase activity	2/484	25/18639	0.08	3.08082644628099	0.136653045211688	0.492076332528325
GO:0042974	nuclear retinoic acid receptor binding	2/484	25/18639	0.08	3.08082644628099	0.136653045211688	0.492076332528325
GO:0000149	SNARE binding	5/484	106/18639	0.0471698113207547	1.81652502728832	0.141924036397632	0.507799643062156
GO:0001637	G protein-coupled chemoattractant receptor activity	2/484	26/18639	0.0769230769230769	2.96233312142403	0.145619600685667	0.507799643062156
GO:0004950	chemokine receptor activity	2/484	26/18639	0.0769230769230769	2.96233312142403	0.145619600685667	0.507799643062156
GO:0008157	protein phosphatase 1 binding	2/484	26/18639	0.0769230769230769	2.96233312142403	0.145619600685667	0.507799643062156
GO:0030247	polysaccharide binding	2/484	26/18639	0.0769230769230769	2.96233312142403	0.145619600685667	0.507799643062156
GO:0070006	metalloaminopeptidase activity	2/484	26/18639	0.0769230769230769	2.96233312142403	0.145619600685667	0.507799643062156
GO:0003743	translation initiation factor activity	3/484	51/18639	0.0588235294117647	2.26531356344191	0.146194546919805	0.507799643062156
GO:0030544	Hsp70 protein binding	3/484	51/18639	0.0588235294117647	2.26531356344191	0.146194546919805	0.507799643062156
GO:0016835	carbon-oxygen lyase activity	4/484	79/18639	0.0506329113924051	1.94989015587405	0.149549691146701	0.517165231498503
GO:0016829	lyase activity	8/484	200/18639	0.04	1.5404132231405	0.150539876383999	0.518306153339645
GO:0000049	tRNA binding	4/484	80/18639	0.05	1.92551652892562	0.154418416971096	0.528009204039041
GO:0035255	ionotropic glutamate receptor binding	2/484	27/18639	0.0740740740740741	2.85261707988981	0.15470333366749	0.528009204039041
GO:0001618	virus receptor activity	4/484	81/18639	0.0493827160493827	1.90174471992654	0.159346005248244	0.541500494025417
GO:0046875	ephrin receptor binding	2/484	28/18639	0.0714285714285714	2.75073789846517	0.16389214926192	0.543846233437397
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	2/484	28/18639	0.0714285714285714	2.75073789846517	0.16389214926192	0.543846233437397
GO:0140272	exogenous protein binding	4/484	82/18639	0.0487804878048781	1.87855271114695	0.164330762814139	0.543846233437397
GO:0140030	modification-dependent protein binding	7/484	173/18639	0.0404624277456647	1.55822146849472	0.164491933057251	0.543846233437397
GO:0003925	G protein activity	3/484	54/18639	0.0555555555555556	2.13946280991736	0.164885864405224	0.543846233437397
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3/484	54/18639	0.0555555555555556	2.13946280991736	0.164885864405224	0.543846233437397
GO:0140463	chromatin-protein adaptor activity	3/484	54/18639	0.0555555555555556	2.13946280991736	0.164885864405224	0.543846233437397
GO:0008135	translation factor activity, RNA binding	4/484	83/18639	0.0481927710843374	1.8559195459524	0.169370981644888	0.550019994400415
GO:0003735	structural constituent of ribosome	7/484	175/18639	0.04	1.5404132231405	0.171235289229006	0.550019994400415
GO:0140313	molecular sequestering activity	3/484	55/18639	0.0545454545454545	2.10056348610068	0.171267407260812	0.550019994400415
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	2/484	29/18639	0.0689655172413793	2.65588486748361	0.173174499328726	0.550019994400415
GO:0010484	histone H3 acetyltransferase activity	2/484	29/18639	0.0689655172413793	2.65588486748361	0.173174499328726	0.550019994400415
GO:0016417	S-acyltransferase activity	2/484	29/18639	0.0689655172413793	2.65588486748361	0.173174499328726	0.550019994400415
GO:0097472	cyclin-dependent protein kinase activity	2/484	29/18639	0.0689655172413793	2.65588486748361	0.173174499328726	0.550019994400415
GO:0099604	ligand-gated calcium channel activity	2/484	29/18639	0.0689655172413793	2.65588486748361	0.173174499328726	0.550019994400415
GO:0004527	exonuclease activity	4/484	84/18639	0.0476190476190476	1.83382526564345	0.174464940898985	0.550019994400415
GO:0051117	ATPase binding	4/484	84/18639	0.0476190476190476	1.83382526564345	0.174464940898985	0.550019994400415
GO:0180051	translation factor activity	4/484	84/18639	0.0476190476190476	1.83382526564345	0.174464940898985	0.550019994400415
GO:0001221	transcription coregulator binding	5/484	115/18639	0.0434782608695652	1.67436219906576	0.179628864961848	0.562940030877382
GO:0005126	cytokine receptor binding	10/484	275/18639	0.0363636363636364	1.40037565740045	0.179997385669074	0.562940030877382
GO:0005319	lipid transporter activity	7/484	178/18639	0.0393258426966292	1.51445120252577	0.181571499295144	0.565609630740827
GO:0015215	nucleotide transmembrane transporter activity	2/484	30/18639	0.0666666666666667	2.56735537190083	0.18253936234078	0.566377072875543
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	4/484	86/18639	0.0465116279069767	1.79117816644244	0.184807145052674	0.566693784634175
GO:0016209	antioxidant activity	4/484	86/18639	0.0465116279069767	1.79117816644244	0.184807145052674	0.566693784634175
GO:0050660	flavin adenine dinucleotide binding	4/484	86/18639	0.0465116279069767	1.79117816644244	0.184807145052674	0.566693784634175
GO:0008408	3'-5' exonuclease activity	3/484	58/18639	0.0517241379310345	1.99191365061271	0.190813944696793	0.580577312352646
GO:0061980	regulatory RNA binding	3/484	58/18639	0.0517241379310345	1.99191365061271	0.190813944696793	0.580577312352646
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	7/484	181/18639	0.0386740331491713	1.48934980137893	0.192162323581224	0.582422486529966
GO:0030246	carbohydrate binding	10/484	280/18639	0.0357142857142857	1.37536894923259	0.194035281895307	0.585837293414677
GO:0004879	nuclear receptor activity	3/484	59/18639	0.0508474576271186	1.95815240229724	0.197451384607235	0.591600522582746
GO:0070888	E-box binding	3/484	59/18639	0.0508474576271186	1.95815240229724	0.197451384607235	0.591600522582746
GO:0022884	macromolecule transmembrane transporter activity	2/484	32/18639	0.0625	2.40689566115702	0.201475058002359	0.592351762291578
GO:0051059	NF-kappaB binding	2/484	32/18639	0.0625	2.40689566115702	0.201475058002359	0.592351762291578
GO:0070717	poly-purine tract binding	2/484	32/18639	0.0625	2.40689566115702	0.201475058002359	0.592351762291578
GO:0071813	lipoprotein particle binding	2/484	32/18639	0.0625	2.40689566115702	0.201475058002359	0.592351762291578
GO:0071814	protein-lipid complex binding	2/484	32/18639	0.0625	2.40689566115702	0.201475058002359	0.592351762291578
GO:0001098	basal transcription machinery binding	3/484	60/18639	0.05	1.92551652892562	0.204143857622367	0.593529363827994
GO:0001099	basal RNA polymerase II transcription machinery binding	3/484	60/18639	0.05	1.92551652892562	0.204143857622367	0.593529363827994
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3/484	60/18639	0.05	1.92551652892562	0.204143857622367	0.593529363827994
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	3/484	61/18639	0.0491803278688525	1.89395068418913	0.210887866521618	0.609028133546243
GO:0019956	chemokine binding	2/484	33/18639	0.0606060606060606	2.33395942900075	0.21102630869373	0.609028133546243
GO:0043178	alcohol binding	4/484	92/18639	0.0434782608695652	1.67436219906576	0.216942052838158	0.622047046158464
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/484	34/18639	0.0588235294117647	2.26531356344191	0.220620872659158	0.622047046158464
GO:0090482	vitamin transmembrane transporter activity	2/484	34/18639	0.0588235294117647	2.26531356344191	0.220620872659158	0.622047046158464
GO:0010485	histone H4 acetyltransferase activity	2/484	35/18639	0.0571428571428571	2.20059031877214	0.230250082163519	0.622047046158464
GO:0043015	gamma-tubulin binding	2/484	35/18639	0.0571428571428571	2.20059031877214	0.230250082163519	0.622047046158464
GO:0061631	ubiquitin conjugating enzyme activity	2/484	35/18639	0.0571428571428571	2.20059031877214	0.230250082163519	0.622047046158464
GO:0140566	histone reader activity	2/484	35/18639	0.0571428571428571	2.20059031877214	0.230250082163519	0.622047046158464
GO:0001094	TFIID-class transcription factor complex binding	1/484	10/18639	0.1	3.85103305785124	0.231385652838562	0.622047046158464
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/484	10/18639	0.1	3.85103305785124	0.231385652838562	0.622047046158464
GO:0004955	prostaglandin receptor activity	1/484	10/18639	0.1	3.85103305785124	0.231385652838562	0.622047046158464
GO:0005381	iron ion transmembrane transporter activity	1/484	10/18639	0.1	3.85103305785124	0.231385652838562	0.622047046158464
GO:0008140	cAMP response element binding protein binding	1/484	10/18639	0.1	3.85103305785124	0.231385652838562	0.622047046158464
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/484	10/18639	0.1	3.85103305785124	0.231385652838562	0.622047046158464
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/484	10/18639	0.1	3.85103305785124	0.231385652838562	0.622047046158464
GO:0031996	thioesterase binding	1/484	10/18639	0.1	3.85103305785124	0.231385652838562	0.622047046158464
GO:0032052	bile acid binding	1/484	10/18639	0.1	3.85103305785124	0.231385652838562	0.622047046158464
GO:0042975	peroxisome proliferator activated receptor binding	1/484	10/18639	0.1	3.85103305785124	0.231385652838562	0.622047046158464
GO:0051864	histone H3K36 demethylase activity	1/484	10/18639	0.1	3.85103305785124	0.231385652838562	0.622047046158464
GO:1905394	retromer complex binding	1/484	10/18639	0.1	3.85103305785124	0.231385652838562	0.622047046158464
GO:1990763	arrestin family protein binding	1/484	10/18639	0.1	3.85103305785124	0.231385652838562	0.622047046158464
GO:0016409	palmitoyltransferase activity	2/484	36/18639	0.0555555555555556	2.13946280991736	0.239905688662328	0.630278014229378
GO:0023023	MHC protein complex binding	2/484	37/18639	0.0540540540540541	2.0816394907304	0.249579846951909	0.630278014229378
GO:0008170	N-methyltransferase activity	4/484	98/18639	0.0408163265306122	1.57185022769438	0.250444794188272	0.630278014229378
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0004954	prostanoid receptor activity	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0005114	type II transforming growth factor beta receptor binding	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0005536	D-glucose binding	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0008172	S-methyltransferase activity	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0015173	aromatic amino acid transmembrane transporter activity	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0019107	myristoyltransferase activity	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0019206	nucleoside kinase activity	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0031731	CCR6 chemokine receptor binding	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0034713	type I transforming growth factor beta receptor binding	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0043522	leucine zipper domain binding	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0047676	arachidonate-CoA ligase activity	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0050786	RAGE receptor binding	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0140031	phosphorylation-dependent protein binding	1/484	11/18639	0.0909090909090909	3.50093914350113	0.251355020170471	0.630278014229378
GO:0042887	amide transmembrane transporter activity	2/484	38/18639	0.0526315789473684	2.02685950413223	0.259265099857311	0.630278014229378
GO:0043531	ADP binding	2/484	38/18639	0.0526315789473684	2.02685950413223	0.259265099857311	0.630278014229378
GO:0003779	actin binding	14/484	443/18639	0.0316027088036117	1.21703076320355	0.26344720004584	0.630278014229378
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	6/484	167/18639	0.0359281437125748	1.38360469144356	0.267416501151902	0.630278014229378
GO:0016874	ligase activity	6/484	167/18639	0.0359281437125748	1.38360469144356	0.267416501151902	0.630278014229378
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	2/484	39/18639	0.0512820512820513	1.97488874761602	0.268954363440834	0.630278014229378
GO:0000340	RNA 7-methylguanosine cap binding	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0003720	telomerase activity	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0004300	enoyl-CoA hydratase activity	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0004875	complement receptor activity	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0005165	neurotrophin receptor binding	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0005436	sodium:phosphate symporter activity	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0015269	calcium-activated potassium channel activity	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0042301	phosphate ion binding	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0070008	serine-type exopeptidase activity	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/484	12/18639	0.0833333333333333	3.20919421487603	0.270806607578539	0.630278014229378
GO:0005096	GTPase activator activity	9/484	271/18639	0.033210332103321	1.27894086792108	0.273112210235037	0.630278014229378
GO:0015036	disulfide oxidoreductase activity	2/484	40/18639	0.05	1.92551652892562	0.278640912714525	0.630278014229378
GO:0030331	nuclear estrogen receptor binding	2/484	40/18639	0.05	1.92551652892562	0.278640912714525	0.630278014229378
GO:0071949	FAD binding	2/484	40/18639	0.05	1.92551652892562	0.278640912714525	0.630278014229378
GO:0042379	chemokine receptor binding	3/484	72/18639	0.0416666666666667	1.60459710743802	0.287522547171017	0.630278014229378
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	2/484	41/18639	0.0487804878048781	1.87855271114695	0.288318367840536	0.630278014229378
GO:0061650	ubiquitin-like protein conjugating enzyme activity	2/484	41/18639	0.0487804878048781	1.87855271114695	0.288318367840536	0.630278014229378
GO:0003964	RNA-directed DNA polymerase activity	1/484	13/18639	0.0769230769230769	2.96233312142403	0.289753813351449	0.630278014229378
GO:0005542	folic acid binding	1/484	13/18639	0.0769230769230769	2.96233312142403	0.289753813351449	0.630278014229378
GO:0008253	5'-nucleotidase activity	1/484	13/18639	0.0769230769230769	2.96233312142403	0.289753813351449	0.630278014229378
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/484	13/18639	0.0769230769230769	2.96233312142403	0.289753813351449	0.630278014229378
GO:0035325	Toll-like receptor binding	1/484	13/18639	0.0769230769230769	2.96233312142403	0.289753813351449	0.630278014229378
GO:0035673	oligopeptide transmembrane transporter activity	1/484	13/18639	0.0769230769230769	2.96233312142403	0.289753813351449	0.630278014229378
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/484	13/18639	0.0769230769230769	2.96233312142403	0.289753813351449	0.630278014229378
GO:0046974	histone H3K9 methyltransferase activity	1/484	13/18639	0.0769230769230769	2.96233312142403	0.289753813351449	0.630278014229378
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/484	13/18639	0.0769230769230769	2.96233312142403	0.289753813351449	0.630278014229378
GO:0097157	pre-mRNA intronic binding	1/484	13/18639	0.0769230769230769	2.96233312142403	0.289753813351449	0.630278014229378
GO:0140333	glycerophospholipid flippase activity	1/484	13/18639	0.0769230769230769	2.96233312142403	0.289753813351449	0.630278014229378
GO:0030295	protein kinase activator activity	5/484	139/18639	0.0359712230215827	1.38526368987455	0.294058502523149	0.630278014229378
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	8/484	243/18639	0.0329218106995885	1.26782981328436	0.297678745066537	0.630278014229378
GO:0004402	histone acetyltransferase activity	2/484	42/18639	0.0476190476190476	1.83382526564345	0.297980680803724	0.630278014229378
GO:0051015	actin filament binding	7/484	209/18639	0.0334928229665072	1.28981968444778	0.300823556458343	0.630278014229378
GO:0003684	damaged DNA binding	3/484	74/18639	0.0405405405405405	1.5612296180478	0.301749722676066	0.630278014229378
GO:0035064	methylated histone binding	3/484	74/18639	0.0405405405405405	1.5612296180478	0.301749722676066	0.630278014229378
GO:0004676	3-phosphoinositide-dependent protein kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0004711	ribosomal protein S6 kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0035175	histone H3S10 kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0035979	histone H2AXS139 kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0044022	histone H3S28 kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0044023	histone H4S1 kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0044024	histone H2AS1 kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0044025	histone H2BS14 kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0072354	histone H3T3 kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0072371	histone H2AS121 kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0072518	Rho-dependent protein serine/threonine kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0140823	histone H2BS36 kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0140855	histone H3S57 kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0140995	histone H2A kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0140997	histone H4 kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0140998	histone H2B kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:1990244	histone H2AT120 kinase activity	8/484	245/18639	0.0326530612244898	1.25748018215551	0.305293693226211	0.630278014229378
GO:0008474	palmitoyl-(protein) hydrolase activity	1/484	14/18639	0.0714285714285714	2.75073789846517	0.308209689778911	0.630278014229378
GO:0015386	potassium:proton antiporter activity	1/484	14/18639	0.0714285714285714	2.75073789846517	0.308209689778911	0.630278014229378
GO:0034236	protein kinase A catalytic subunit binding	1/484	14/18639	0.0714285714285714	2.75073789846517	0.308209689778911	0.630278014229378
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/484	14/18639	0.0714285714285714	2.75073789846517	0.308209689778911	0.630278014229378
GO:0042043	neurexin family protein binding	1/484	14/18639	0.0714285714285714	2.75073789846517	0.308209689778911	0.630278014229378
GO:0042813	Wnt receptor activity	1/484	14/18639	0.0714285714285714	2.75073789846517	0.308209689778911	0.630278014229378
GO:0046030	inositol trisphosphate phosphatase activity	1/484	14/18639	0.0714285714285714	2.75073789846517	0.308209689778911	0.630278014229378
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/484	14/18639	0.0714285714285714	2.75073789846517	0.308209689778911	0.630278014229378
GO:0098599	palmitoyl hydrolase activity	1/484	14/18639	0.0714285714285714	2.75073789846517	0.308209689778911	0.630278014229378
GO:1901612	cardiolipin binding	1/484	14/18639	0.0714285714285714	2.75073789846517	0.308209689778911	0.630278014229378
GO:0004677	DNA-dependent protein kinase activity	8/484	246/18639	0.032520325203252	1.25236847409796	0.309117242647529	0.630278014229378
GO:0140857	histone H3T45 kinase activity	8/484	246/18639	0.032520325203252	1.25236847409796	0.309117242647529	0.630278014229378
GO:0033218	amide binding	8/484	247/18639	0.0323886639676113	1.24729815638907	0.31295092951392	0.631533366756883
GO:0035402	histone H3T11 kinase activity	8/484	247/18639	0.0323886639676113	1.24729815638907	0.31295092951392	0.631533366756883
GO:0035403	histone H3T6 kinase activity	8/484	247/18639	0.0323886639676113	1.24729815638907	0.31295092951392	0.631533366756883
GO:0042393	histone binding	8/484	247/18639	0.0323886639676113	1.24729815638907	0.31295092951392	0.631533366756883
GO:0140034	methylation-dependent protein binding	3/484	76/18639	0.0394736842105263	1.52014462809917	0.316009684562586	0.63503584757152
GO:0004679	AMP-activated protein kinase activity	8/484	248/18639	0.032258064516129	1.24226872833911	0.316794319410087	0.63503584757152
GO:0019205	nucleobase-containing compound kinase activity	2/484	44/18639	0.0454545454545455	1.75046957175056	0.317237270515219	0.63503584757152
GO:0016741	transferase activity, transferring one-carbon groups	7/484	215/18639	0.0325581395348837	1.25382471650971	0.325740161588233	0.63503584757152
GO:0000774	adenyl-nucleotide exchange factor activity	1/484	15/18639	0.0666666666666667	2.56735537190083	0.326186952068683	0.63503584757152
GO:0004467	long-chain fatty acid-CoA ligase activity	1/484	15/18639	0.0666666666666667	2.56735537190083	0.326186952068683	0.63503584757152
GO:0004953	icosanoid receptor activity	1/484	15/18639	0.0666666666666667	2.56735537190083	0.326186952068683	0.63503584757152
GO:0005523	tropomyosin binding	1/484	15/18639	0.0666666666666667	2.56735537190083	0.326186952068683	0.63503584757152
GO:0008252	nucleotidase activity	1/484	15/18639	0.0666666666666667	2.56735537190083	0.326186952068683	0.63503584757152
GO:0016846	carbon-sulfur lyase activity	1/484	15/18639	0.0666666666666667	2.56735537190083	0.326186952068683	0.63503584757152
GO:0050700	CARD domain binding	1/484	15/18639	0.0666666666666667	2.56735537190083	0.326186952068683	0.63503584757152
GO:0061578	K63-linked deubiquitinase activity	1/484	15/18639	0.0666666666666667	2.56735537190083	0.326186952068683	0.63503584757152
GO:0120283	protein serine/threonine kinase binding	1/484	15/18639	0.0666666666666667	2.56735537190083	0.326186952068683	0.63503584757152
GO:0004715	non-membrane spanning protein tyrosine kinase activity	2/484	45/18639	0.0444444444444444	1.71157024793388	0.326820996711967	0.63503584757152
GO:0046915	transition metal ion transmembrane transporter activity	2/484	45/18639	0.0444444444444444	1.71157024793388	0.326820996711967	0.63503584757152
GO:0019209	kinase activator activity	5/484	148/18639	0.0337837837837838	1.3010246817065	0.339985530404221	0.655309885319168
GO:0003688	DNA replication origin binding	1/484	16/18639	0.0625	2.40689566115702	0.343697987034252	0.655309885319168
GO:0015385	sodium:proton antiporter activity	1/484	16/18639	0.0625	2.40689566115702	0.343697987034252	0.655309885319168
GO:0015923	mannosidase activity	1/484	16/18639	0.0625	2.40689566115702	0.343697987034252	0.655309885319168
GO:0017070	U6 snRNA binding	1/484	16/18639	0.0625	2.40689566115702	0.343697987034252	0.655309885319168
GO:0030275	LRR domain binding	1/484	16/18639	0.0625	2.40689566115702	0.343697987034252	0.655309885319168
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/484	16/18639	0.0625	2.40689566115702	0.343697987034252	0.655309885319168
GO:0019887	protein kinase regulator activity	8/484	255/18639	0.0313725490196078	1.20816723383568	0.34393334108471	0.655309885319168
GO:0001784	phosphotyrosine residue binding	2/484	47/18639	0.0425531914893617	1.63873747142606	0.345875075234481	0.655825927678907
GO:0061733	protein-lysine-acetyltransferase activity	2/484	47/18639	0.0425531914893617	1.63873747142606	0.345875075234481	0.655825927678907
GO:0015101	organic cation transmembrane transporter activity	3/484	81/18639	0.037037037037037	1.4263085399449	0.351668522728278	0.660122532223447
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	2/484	48/18639	0.0416666666666667	1.60459710743802	0.355336541882804	0.660122532223447
GO:0016879	ligase activity, forming carbon-nitrogen bonds	2/484	48/18639	0.0416666666666667	1.60459710743802	0.355336541882804	0.660122532223447
GO:0032266	phosphatidylinositol-3-phosphate binding	2/484	48/18639	0.0416666666666667	1.60459710743802	0.355336541882804	0.660122532223447
GO:0004550	nucleoside diphosphate kinase activity	1/484	17/18639	0.0588235294117647	2.26531356344191	0.360754861559056	0.660122532223447
GO:0004659	prenyltransferase activity	1/484	17/18639	0.0588235294117647	2.26531356344191	0.360754861559056	0.660122532223447
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/484	17/18639	0.0588235294117647	2.26531356344191	0.360754861559056	0.660122532223447
GO:0005092	GDP-dissociation inhibitor activity	1/484	17/18639	0.0588235294117647	2.26531356344191	0.360754861559056	0.660122532223447
GO:0008429	phosphatidylethanolamine binding	1/484	17/18639	0.0588235294117647	2.26531356344191	0.360754861559056	0.660122532223447
GO:0015278	intracellularly gated calcium channel activity	1/484	17/18639	0.0588235294117647	2.26531356344191	0.360754861559056	0.660122532223447
GO:0016018	cyclosporin A binding	1/484	17/18639	0.0588235294117647	2.26531356344191	0.360754861559056	0.660122532223447
GO:0036041	long-chain fatty acid binding	1/484	17/18639	0.0588235294117647	2.26531356344191	0.360754861559056	0.660122532223447
GO:0045125	bioactive lipid receptor activity	1/484	17/18639	0.0588235294117647	2.26531356344191	0.360754861559056	0.660122532223447
GO:0045236	CXCR chemokine receptor binding	1/484	17/18639	0.0588235294117647	2.26531356344191	0.360754861559056	0.660122532223447
GO:0048038	quinone binding	1/484	17/18639	0.0588235294117647	2.26531356344191	0.360754861559056	0.660122532223447
GO:0046982	protein heterodimerization activity	11/484	369/18639	0.029810298102981	1.1480044345898	0.363541822739459	0.662795841280667
GO:0001222	transcription corepressor binding	2/484	49/18639	0.0408163265306122	1.57185022769438	0.364748794182482	0.662795841280667
GO:0016763	pentosyltransferase activity	2/484	49/18639	0.0408163265306122	1.57185022769438	0.364748794182482	0.662795841280667
GO:0030165	PDZ domain binding	3/484	83/18639	0.036144578313253	1.3919396594643	0.365885551123117	0.663325999149301
GO:0015605	organophosphate ester transmembrane transporter activity	2/484	50/18639	0.04	1.5404132231405	0.37410801079478	0.667195776377808
GO:0032813	tumor necrosis factor receptor superfamily binding	2/484	50/18639	0.04	1.5404132231405	0.37410801079478	0.667195776377808
GO:0048020	CCR chemokine receptor binding	2/484	50/18639	0.04	1.5404132231405	0.37410801079478	0.667195776377808
GO:0000400	four-way junction DNA binding	1/484	18/18639	0.0555555555555556	2.13946280991736	0.37736933084299	0.667195776377808
GO:0000900	mRNA regulatory element binding translation repressor activity	1/484	18/18639	0.0555555555555556	2.13946280991736	0.37736933084299	0.667195776377808
GO:0008409	5'-3' exonuclease activity	1/484	18/18639	0.0555555555555556	2.13946280991736	0.37736933084299	0.667195776377808
GO:0008525	phosphatidylcholine transporter activity	1/484	18/18639	0.0555555555555556	2.13946280991736	0.37736933084299	0.667195776377808
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/484	18/18639	0.0555555555555556	2.13946280991736	0.37736933084299	0.667195776377808
GO:0035615	clathrin adaptor activity	1/484	18/18639	0.0555555555555556	2.13946280991736	0.37736933084299	0.667195776377808
GO:0070628	proteasome binding	1/484	18/18639	0.0555555555555556	2.13946280991736	0.37736933084299	0.667195776377808
GO:1901611	phosphatidylglycerol binding	1/484	18/18639	0.0555555555555556	2.13946280991736	0.37736933084299	0.667195776377808
GO:0016830	carbon-carbon lyase activity	2/484	51/18639	0.0392156862745098	1.5102090422946	0.383410601157023	0.674684656625393
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	7/484	229/18639	0.0305676855895196	1.17717167707243	0.384892164767358	0.674684656625393
GO:0003697	single-stranded DNA binding	4/484	121/18639	0.0330578512396694	1.27306877945496	0.385042963271562	0.674684656625393
GO:0004540	RNA nuclease activity	4/484	121/18639	0.0330578512396694	1.27306877945496	0.385042963271562	0.674684656625393
GO:0005085	guanyl-nucleotide exchange factor activity	7/484	230/18639	0.0304347826086957	1.17205353934603	0.389143662167632	0.678986779017304
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	4/484	122/18639	0.0327868852459016	1.26263378945942	0.390934298290633	0.678986779017304
GO:0008301	DNA binding, bending	1/484	19/18639	0.0526315789473684	2.02685950413223	0.393552846436781	0.678986779017304
GO:0022821	solute:potassium antiporter activity	1/484	19/18639	0.0526315789473684	2.02685950413223	0.393552846436781	0.678986779017304
GO:0034987	immunoglobulin receptor binding	1/484	19/18639	0.0526315789473684	2.02685950413223	0.393552846436781	0.678986779017304
GO:0050145	nucleoside monophosphate kinase activity	1/484	19/18639	0.0526315789473684	2.02685950413223	0.393552846436781	0.678986779017304
GO:0140036	ubiquitin-modified protein reader activity	1/484	19/18639	0.0526315789473684	2.02685950413223	0.393552846436781	0.678986779017304
GO:0004197	cysteine-type endopeptidase activity	3/484	88/18639	0.0340909090909091	1.31285217881292	0.401160617595917	0.690237683883885
GO:0034212	protein N-acetyltransferase activity	2/484	53/18639	0.0377358490566038	1.45322002183066	0.401832638898007	0.690237683883885
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/484	20/18639	0.05	1.92551652892562	0.409316564069681	0.691598835544912
GO:0016004	phospholipase activator activity	1/484	20/18639	0.05	1.92551652892562	0.409316564069681	0.691598835544912
GO:0042288	MHC class I protein binding	1/484	20/18639	0.05	1.92551652892562	0.409316564069681	0.691598835544912
GO:0052745	inositol phosphate phosphatase activity	1/484	20/18639	0.05	1.92551652892562	0.409316564069681	0.691598835544912
GO:0015485	cholesterol binding	2/484	54/18639	0.037037037037037	1.4263085399449	0.410945976378498	0.691598835544912
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	2/484	54/18639	0.037037037037037	1.4263085399449	0.410945976378498	0.691598835544912
GO:0015631	tubulin binding	11/484	385/18639	0.0285714285714286	1.10029515938607	0.416570509985283	0.691598835544912
GO:0072341	modified amino acid binding	3/484	91/18639	0.032967032967033	1.26957133775316	0.422065236953966	0.691598835544912
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/484	21/18639	0.0476190476190476	1.83382526564345	0.424671351275776	0.691598835544912
GO:0005123	death receptor binding	1/484	21/18639	0.0476190476190476	1.83382526564345	0.424671351275776	0.691598835544912
GO:0009975	cyclase activity	1/484	21/18639	0.0476190476190476	1.83382526564345	0.424671351275776	0.691598835544912
GO:0010314	phosphatidylinositol-5-phosphate binding	1/484	21/18639	0.0476190476190476	1.83382526564345	0.424671351275776	0.691598835544912
GO:0015174	basic amino acid transmembrane transporter activity	1/484	21/18639	0.0476190476190476	1.83382526564345	0.424671351275776	0.691598835544912
GO:0140312	cargo adaptor activity	1/484	21/18639	0.0476190476190476	1.83382526564345	0.424671351275776	0.691598835544912
GO:1904047	S-adenosyl-L-methionine binding	1/484	21/18639	0.0476190476190476	1.83382526564345	0.424671351275776	0.691598835544912
GO:0030170	pyridoxal phosphate binding	2/484	56/18639	0.0357142857142857	1.37536894923259	0.428963491078118	0.691598835544912
GO:0008168	methyltransferase activity	6/484	204/18639	0.0294117647058824	1.13265678172095	0.436991082818019	0.691598835544912
GO:0004601	peroxidase activity	2/484	57/18639	0.0350877192982456	1.35123966942149	0.437862706130882	0.691598835544912
GO:0015932	nucleobase-containing compound transmembrane transporter activity	2/484	57/18639	0.0350877192982456	1.35123966942149	0.437862706130882	0.691598835544912
GO:0070279	vitamin B6 binding	2/484	57/18639	0.0350877192982456	1.35123966942149	0.437862706130882	0.691598835544912
GO:0004407	histone deacetylase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0008093	cytoskeletal anchor activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0032931	histone H3K56 acetyltransferase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0033558	protein lysine deacetylase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0034062	5'-3' RNA polymerase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0043992	histone H3K9 acetyltransferase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0043993	histone H3K18 acetyltransferase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0043994	histone H3K23 acetyltransferase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0043999	histone H2AK5 acetyltransferase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0044012	histone H2AK9 acetyltransferase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0044014	histone H2BK5 acetyltransferase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0044015	histone H2BK12 acetyltransferase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0044016	histone H3K4 acetyltransferase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0044017	histone H3K27 acetyltransferase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0044018	histone H3K36 acetyltransferase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0046972	histone H4K16 acetyltransferase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0050321	tau-protein kinase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0097747	RNA polymerase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0140035	ubiquitin-like protein reader activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0140517	protein-RNA adaptor activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0140908	histone H3K122 acetyltransferase activity	1/484	22/18639	0.0454545454545455	1.75046957175056	0.43962779482409	0.691598835544912
GO:0016410	N-acyltransferase activity	3/484	94/18639	0.0319148936170213	1.22905310356954	0.442717561188149	0.695066571065394
GO:0004602	glutathione peroxidase activity	1/484	23/18639	0.0434782608695652	1.67436219906576	0.454196207957524	0.700988820939598
GO:0042171	lysophosphatidic acid acyltransferase activity	1/484	23/18639	0.0434782608695652	1.67436219906576	0.454196207957524	0.700988820939598
GO:0043274	phospholipase binding	1/484	23/18639	0.0434782608695652	1.67436219906576	0.454196207957524	0.700988820939598
GO:0044013	histone H2B acetyltransferase activity	1/484	23/18639	0.0434782608695652	1.67436219906576	0.454196207957524	0.700988820939598
GO:0071617	lysophospholipid acyltransferase activity	1/484	23/18639	0.0434782608695652	1.67436219906576	0.454196207957524	0.700988820939598
GO:0001786	phosphatidylserine binding	2/484	59/18639	0.0338983050847458	1.30543493486483	0.45543094606192	0.700988820939598
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	2/484	59/18639	0.0338983050847458	1.30543493486483	0.45543094606192	0.700988820939598
GO:0045309	protein phosphorylated amino acid binding	2/484	59/18639	0.0338983050847458	1.30543493486483	0.45543094606192	0.700988820939598
GO:0070063	RNA polymerase binding	2/484	59/18639	0.0338983050847458	1.30543493486483	0.45543094606192	0.700988820939598
GO:0004896	cytokine receptor activity	3/484	96/18639	0.03125	1.20344783057851	0.456325142678274	0.700988820939598
GO:0016407	acetyltransferase activity	3/484	96/18639	0.03125	1.20344783057851	0.456325142678274	0.700988820939598
GO:0004518	nuclease activity	6/484	209/18639	0.0287081339712919	1.10555972952667	0.459909964161521	0.700988820939598
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/484	24/18639	0.0416666666666667	1.60459710743802	0.468386637445522	0.700988820939598
GO:0005315	phosphate transmembrane transporter activity	1/484	24/18639	0.0416666666666667	1.60459710743802	0.468386637445522	0.700988820939598
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/484	24/18639	0.0416666666666667	1.60459710743802	0.468386637445522	0.700988820939598
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/484	24/18639	0.0416666666666667	1.60459710743802	0.468386637445522	0.700988820939598
GO:0043998	histone H2A acetyltransferase activity	1/484	24/18639	0.0416666666666667	1.60459710743802	0.468386637445522	0.700988820939598
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/484	24/18639	0.0416666666666667	1.60459710743802	0.468386637445522	0.700988820939598
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/484	24/18639	0.0416666666666667	1.60459710743802	0.468386637445522	0.700988820939598
GO:0048027	mRNA 5'-UTR binding	1/484	24/18639	0.0416666666666667	1.60459710743802	0.468386637445522	0.700988820939598
GO:0050431	transforming growth factor beta binding	1/484	24/18639	0.0416666666666667	1.60459710743802	0.468386637445522	0.700988820939598
GO:0060229	lipase activator activity	1/484	24/18639	0.0416666666666667	1.60459710743802	0.468386637445522	0.700988820939598
GO:0070840	dynein complex binding	1/484	24/18639	0.0416666666666667	1.60459710743802	0.468386637445522	0.700988820939598
GO:0140033	acetylation-dependent protein binding	1/484	24/18639	0.0416666666666667	1.60459710743802	0.468386637445522	0.700988820939598
GO:0019207	kinase regulator activity	8/484	287/18639	0.0278745644599303	1.07345869208397	0.469763863090026	0.700988820939598
GO:0042626	ATPase-coupled transmembrane transporter activity	3/484	98/18639	0.0306122448979592	1.17888767077079	0.469791205881627	0.700988820939598
GO:0002020	protease binding	4/484	136/18639	0.0294117647058824	1.13265678172095	0.472056384703208	0.700988820939598
GO:0044325	transmembrane transporter binding	4/484	136/18639	0.0294117647058824	1.13265678172095	0.472056384703208	0.700988820939598
GO:0005537	D-mannose binding	1/484	25/18639	0.04	1.5404132231405	0.482208870455265	0.700988820939598
GO:0008139	nuclear localization sequence binding	1/484	25/18639	0.04	1.5404132231405	0.482208870455265	0.700988820939598
GO:0008483	transaminase activity	1/484	25/18639	0.04	1.5404132231405	0.482208870455265	0.700988820939598
GO:0015645	fatty acid ligase activity	1/484	25/18639	0.04	1.5404132231405	0.482208870455265	0.700988820939598
GO:0015662	P-type ion transporter activity	1/484	25/18639	0.04	1.5404132231405	0.482208870455265	0.700988820939598
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/484	25/18639	0.04	1.5404132231405	0.482208870455265	0.700988820939598
GO:0017025	TBP-class protein binding	1/484	25/18639	0.04	1.5404132231405	0.482208870455265	0.700988820939598
GO:0047617	fatty acyl-CoA hydrolase activity	1/484	25/18639	0.04	1.5404132231405	0.482208870455265	0.700988820939598
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	1/484	25/18639	0.04	1.5404132231405	0.482208870455265	0.700988820939598
GO:0120020	cholesterol transfer activity	1/484	25/18639	0.04	1.5404132231405	0.482208870455265	0.700988820939598
GO:0120515	fatty acid-CoA ligase activity	1/484	25/18639	0.04	1.5404132231405	0.482208870455265	0.700988820939598
GO:0140358	P-type transmembrane transporter activity	1/484	25/18639	0.04	1.5404132231405	0.482208870455265	0.700988820939598
GO:0140767	enzyme-substrate adaptor activity	4/484	139/18639	0.0287769784172662	1.10821095189964	0.488953690115299	0.703182781487273
GO:0005507	copper ion binding	2/484	63/18639	0.0317460317460317	1.22255017709563	0.489594491838045	0.703182781487273
GO:1901682	sulfur compound transmembrane transporter activity	2/484	63/18639	0.0317460317460317	1.22255017709563	0.489594491838045	0.703182781487273
GO:0004435	phosphatidylinositol phospholipase C activity	1/484	26/18639	0.0384615384615385	1.48116656071202	0.495672441246049	0.703182781487273
GO:0005112	Notch binding	1/484	26/18639	0.0384615384615385	1.48116656071202	0.495672441246049	0.703182781487273
GO:0005160	transforming growth factor beta receptor binding	1/484	26/18639	0.0384615384615385	1.48116656071202	0.495672441246049	0.703182781487273
GO:0005227	calcium-activated cation channel activity	1/484	26/18639	0.0384615384615385	1.48116656071202	0.495672441246049	0.703182781487273
GO:0016289	acyl-CoA hydrolase activity	1/484	26/18639	0.0384615384615385	1.48116656071202	0.495672441246049	0.703182781487273
GO:0034237	protein kinase A regulatory subunit binding	1/484	26/18639	0.0384615384615385	1.48116656071202	0.495672441246049	0.703182781487273
GO:0043548	phosphatidylinositol 3-kinase binding	1/484	26/18639	0.0384615384615385	1.48116656071202	0.495672441246049	0.703182781487273
GO:0051139	metal cation:proton antiporter activity	1/484	26/18639	0.0384615384615385	1.48116656071202	0.495672441246049	0.703182781487273
GO:0097602	cullin family protein binding	1/484	26/18639	0.0384615384615385	1.48116656071202	0.495672441246049	0.703182781487273
GO:0120014	phospholipid transfer activity	1/484	26/18639	0.0384615384615385	1.48116656071202	0.495672441246049	0.703182781487273
GO:0008238	exopeptidase activity	3/484	102/18639	0.0294117647058824	1.13265678172095	0.496258931138789	0.703182781487273
GO:0016853	isomerase activity	5/484	180/18639	0.0277777777777778	1.06973140495868	0.502825077783397	0.706898248827844
GO:0038024	cargo receptor activity	2/484	65/18639	0.0307692307692308	1.18493324856961	0.506165182404373	0.706898248827844
GO:0120013	lipid transfer activity	2/484	65/18639	0.0307692307692308	1.18493324856961	0.506165182404373	0.706898248827844
GO:0160215	deacylase activity	2/484	65/18639	0.0307692307692308	1.18493324856961	0.506165182404373	0.706898248827844
GO:0004364	glutathione transferase activity	1/484	27/18639	0.037037037037037	1.4263085399449	0.508786637691378	0.706898248827844
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/484	27/18639	0.037037037037037	1.4263085399449	0.508786637691378	0.706898248827844
GO:0005385	zinc ion transmembrane transporter activity	1/484	27/18639	0.037037037037037	1.4263085399449	0.508786637691378	0.706898248827844
GO:0008320	protein transmembrane transporter activity	1/484	27/18639	0.037037037037037	1.4263085399449	0.508786637691378	0.706898248827844
GO:0016405	CoA-ligase activity	1/484	27/18639	0.037037037037037	1.4263085399449	0.508786637691378	0.706898248827844
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/484	27/18639	0.037037037037037	1.4263085399449	0.508786637691378	0.706898248827844
GO:0023026	MHC class II protein complex binding	1/484	27/18639	0.037037037037037	1.4263085399449	0.508786637691378	0.706898248827844
GO:0008235	metalloexopeptidase activity	2/484	66/18639	0.0303030303030303	1.16697971450038	0.514318412346622	0.713321472954237
GO:0019955	cytokine binding	4/484	144/18639	0.0277777777777778	1.06973140495868	0.516605919531901	0.715230417694078
GO:0019789	SUMO transferase activity	1/484	28/18639	0.0357142857142857	1.37536894923259	0.521560507633209	0.716765469824443
GO:0036408	histone H3K14 acetyltransferase activity	1/484	28/18639	0.0357142857142857	1.37536894923259	0.521560507633209	0.716765469824443
GO:0046966	nuclear thyroid hormone receptor binding	1/484	28/18639	0.0357142857142857	1.37536894923259	0.521560507633209	0.716765469824443
GO:0051537	2 iron, 2 sulfur cluster binding	1/484	28/18639	0.0357142857142857	1.37536894923259	0.521560507633209	0.716765469824443
GO:0061135	endopeptidase regulator activity	5/484	184/18639	0.0271739130434783	1.0464763744161	0.522280062088639	0.716765469824443
GO:0019888	protein phosphatase regulator activity	3/484	107/18639	0.0280373831775701	1.07972889472465	0.528383826199411	0.72387662053497
GO:0032934	sterol binding	2/484	68/18639	0.0294117647058824	1.13265678172095	0.530355778321809	0.725312344917457
GO:0004629	phospholipase C activity	1/484	29/18639	0.0344827586206897	1.32794243374181	0.534002865072655	0.72539691088353
GO:0005496	steroid binding	3/484	108/18639	0.0277777777777778	1.06973140495868	0.534671503241482	0.72539691088353
GO:0061134	peptidase regulator activity	6/484	226/18639	0.0265486725663717	1.02239815695166	0.535713365793364	0.72539691088353
GO:0031406	carboxylic acid binding	5/484	187/18639	0.0267379679144385	1.02968798338268	0.536654460665113	0.72539691088353
GO:0008080	N-acetyltransferase activity	2/484	69/18639	0.0289855072463768	1.11624146604384	0.5382382954356	0.72539691088353
GO:0001965	G-protein alpha-subunit binding	1/484	30/18639	0.0333333333333333	1.28367768595041	0.546122296201341	0.72539691088353
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/484	30/18639	0.0333333333333333	1.28367768595041	0.546122296201341	0.72539691088353
GO:0016769	transferase activity, transferring nitrogenous groups	1/484	30/18639	0.0333333333333333	1.28367768595041	0.546122296201341	0.72539691088353
GO:0022839	monoatomic ion-gated channel activity	1/484	30/18639	0.0333333333333333	1.28367768595041	0.546122296201341	0.72539691088353
GO:0031210	phosphatidylcholine binding	1/484	30/18639	0.0333333333333333	1.28367768595041	0.546122296201341	0.72539691088353
GO:0033612	receptor serine/threonine kinase binding	1/484	30/18639	0.0333333333333333	1.28367768595041	0.546122296201341	0.72539691088353
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/484	30/18639	0.0333333333333333	1.28367768595041	0.546122296201341	0.72539691088353
GO:0043995	histone H4K5 acetyltransferase activity	1/484	30/18639	0.0333333333333333	1.28367768595041	0.546122296201341	0.72539691088353
GO:0043996	histone H4K8 acetyltransferase activity	1/484	30/18639	0.0333333333333333	1.28367768595041	0.546122296201341	0.72539691088353
GO:0043997	histone H4K12 acetyltransferase activity	1/484	30/18639	0.0333333333333333	1.28367768595041	0.546122296201341	0.72539691088353
GO:0048019	receptor antagonist activity	1/484	30/18639	0.0333333333333333	1.28367768595041	0.546122296201341	0.72539691088353
GO:0043177	organic acid binding	5/484	189/18639	0.0264550264550265	1.01879181424636	0.546126846283014	0.72539691088353
GO:0019842	vitamin binding	4/484	150/18639	0.0266666666666667	1.02694214876033	0.548838365695661	0.727767089647118
GO:0005164	tumor necrosis factor receptor binding	1/484	31/18639	0.032258064516129	1.24226872833911	0.557927165277516	0.732396027998077
GO:0016411	acylglycerol O-acyltransferase activity	1/484	31/18639	0.032258064516129	1.24226872833911	0.557927165277516	0.732396027998077
GO:0016878	acid-thiol ligase activity	1/484	31/18639	0.032258064516129	1.24226872833911	0.557927165277516	0.732396027998077
GO:0017147	Wnt-protein binding	1/484	31/18639	0.032258064516129	1.24226872833911	0.557927165277516	0.732396027998077
GO:0070273	phosphatidylinositol-4-phosphate binding	1/484	31/18639	0.032258064516129	1.24226872833911	0.557927165277516	0.732396027998077
GO:0072349	modified amino acid transmembrane transporter activity	1/484	31/18639	0.032258064516129	1.24226872833911	0.557927165277516	0.732396027998077
GO:0031369	translation initiation factor binding	1/484	32/18639	0.03125	1.20344783057851	0.569425620350909	0.743758921756178
GO:0043425	bHLH transcription factor binding	1/484	32/18639	0.03125	1.20344783057851	0.569425620350909	0.743758921756178
GO:0120015	sterol transfer activity	1/484	32/18639	0.03125	1.20344783057851	0.569425620350909	0.743758921756178
GO:0141003	histone H2AX kinase activity	9/484	354/18639	0.0254237288135593	0.97907620114862	0.572889248148249	0.747039966439162
GO:0031491	nucleosome binding	2/484	74/18639	0.027027027027027	1.0408197453652	0.576265676300386	0.748954562741396
GO:0048029	monosaccharide binding	2/484	74/18639	0.027027027027027	1.0408197453652	0.576265676300386	0.748954562741396
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/484	33/18639	0.0303030303030303	1.16697971450038	0.580625598840195	0.750891425188721
GO:0071889	14-3-3 protein binding	1/484	33/18639	0.0303030303030303	1.16697971450038	0.580625598840195	0.750891425188721
GO:0140311	protein sequestering activity	1/484	33/18639	0.0303030303030303	1.16697971450038	0.580625598840195	0.750891425188721
GO:0140996	histone H3 kinase activity	9/484	357/18639	0.0252100840336134	0.970848670046531	0.583071194067311	0.751746717531717
GO:0015294	solute:monoatomic cation symporter activity	3/484	116/18639	0.0258620689655172	0.995956825306355	0.583202230543714	0.751746717531717
GO:0019208	phosphatase regulator activity	3/484	117/18639	0.0256410256410256	0.98744437380801	0.58903855026237	0.753822798504889
GO:0017022	myosin binding	2/484	76/18639	0.0263157894736842	1.01342975206612	0.590823333377375	0.753822798504889
GO:0051536	iron-sulfur cluster binding	2/484	76/18639	0.0263157894736842	1.01342975206612	0.590823333377375	0.753822798504889
GO:0008376	acetylgalactosaminyltransferase activity	1/484	34/18639	0.0294117647058824	1.13265678172095	0.591534832966893	0.753822798504889
GO:0015035	protein-disulfide reductase activity	1/484	34/18639	0.0294117647058824	1.13265678172095	0.591534832966893	0.753822798504889
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/484	34/18639	0.0294117647058824	1.13265678172095	0.591534832966893	0.753822798504889
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/484	34/18639	0.0294117647058824	1.13265678172095	0.591534832966893	0.753822798504889
GO:0035173	histone kinase activity	9/484	360/18639	0.025	0.96275826446281	0.593141921467798	0.754645718561137
GO:0003724	RNA helicase activity	2/484	77/18639	0.025974025974026	1.00026832671461	0.597961411754391	0.758319399397733
GO:0051540	metal cluster binding	2/484	77/18639	0.025974025974026	1.00026832671461	0.597961411754391	0.758319399397733
GO:0034061	DNA polymerase activity	1/484	35/18639	0.0285714285714286	1.10029515938607	0.602160855049346	0.762413340667317
GO:0005178	integrin binding	4/484	161/18639	0.0248447204968944	0.956778399466147	0.604852088024012	0.764587583089935
GO:0008186	ATP-dependent activity, acting on RNA	2/484	79/18639	0.0253164556962025	0.974945077937023	0.611956006087645	0.76685986776462
GO:0033293	monocarboxylic acid binding	2/484	79/18639	0.0253164556962025	0.974945077937023	0.611956006087645	0.76685986776462
GO:0000993	RNA polymerase II complex binding	1/484	36/18639	0.0277777777777778	1.06973140495868	0.612511002660403	0.76685986776462
GO:0004190	aspartic-type endopeptidase activity	1/484	36/18639	0.0277777777777778	1.06973140495868	0.612511002660403	0.76685986776462
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/484	36/18639	0.0277777777777778	1.06973140495868	0.612511002660403	0.76685986776462
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/484	36/18639	0.0277777777777778	1.06973140495868	0.612511002660403	0.76685986776462
GO:0019213	deacetylase activity	1/484	37/18639	0.027027027027027	1.0408197453652	0.622592423652306	0.775769924709619
GO:0043394	proteoglycan binding	1/484	37/18639	0.027027027027027	1.0408197453652	0.622592423652306	0.775769924709619
GO:0070001	aspartic-type peptidase activity	1/484	37/18639	0.027027027027027	1.0408197453652	0.622592423652306	0.775769924709619
GO:0030971	receptor tyrosine kinase binding	2/484	81/18639	0.0246913580246914	0.950872359963269	0.625575829978128	0.778252023031427
GO:0005109	frizzled binding	1/484	38/18639	0.0263157894736842	1.01342975206612	0.632412081052171	0.785511841180307
GO:0001540	amyloid-beta binding	2/484	83/18639	0.0240963855421687	0.927959772976202	0.638822453176215	0.792220577793568
GO:0000217	DNA secondary structure binding	1/484	39/18639	0.0256410256410256	0.98744437380801	0.641976757831417	0.79362481086246
GO:0016776	phosphotransferase activity, phosphate group as acceptor	1/484	39/18639	0.0256410256410256	0.98744437380801	0.641976757831417	0.79362481086246
GO:0004519	endonuclease activity	3/484	127/18639	0.0236220472440945	0.909692848311316	0.644451705172733	0.795236464624084
GO:0004860	protein kinase inhibitor activity	2/484	84/18639	0.0238095238095238	0.916912632821724	0.64530653244018	0.795236464624084
GO:0050997	quaternary ammonium group binding	1/484	40/18639	0.025	0.96275826446281	0.651293061552362	0.801355882944521
GO:0001664	G protein-coupled receptor binding	7/484	297/18639	0.0235690235690236	0.907650889055848	0.654971049990054	0.802458872573838
GO:0016798	hydrolase activity, acting on glycosyl bonds	3/484	130/18639	0.0230769230769231	0.888699936427209	0.660009498851125	0.802458872573838
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	3/484	130/18639	0.0230769230769231	0.888699936427209	0.660009498851125	0.802458872573838
GO:0008227	G protein-coupled amine receptor activity	1/484	41/18639	0.024390243902439	0.939276355573473	0.660367428895158	0.802458872573838
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/484	41/18639	0.024390243902439	0.939276355573473	0.660367428895158	0.802458872573838
GO:0042287	MHC protein binding	1/484	41/18639	0.024390243902439	0.939276355573473	0.660367428895158	0.802458872573838
GO:0140318	protein transporter activity	1/484	41/18639	0.024390243902439	0.939276355573473	0.660367428895158	0.802458872573838
GO:0140828	metal cation:monoatomic cation antiporter activity	1/484	41/18639	0.024390243902439	0.939276355573473	0.660367428895158	0.802458872573838
GO:0008081	phosphoric diester hydrolase activity	2/484	87/18639	0.0229885057471264	0.885294955827871	0.664206401206146	0.805715969483856
GO:0004520	DNA endonuclease activity	1/484	42/18639	0.0238095238095238	0.916912632821724	0.66920613006812	0.805715969483856
GO:0008307	structural constituent of muscle	1/484	42/18639	0.0238095238095238	0.916912632821724	0.66920613006812	0.805715969483856
GO:0019894	kinesin binding	1/484	42/18639	0.0238095238095238	0.916912632821724	0.66920613006812	0.805715969483856
GO:0042056	chemoattractant activity	1/484	42/18639	0.0238095238095238	0.916912632821724	0.66920613006812	0.805715969483856
GO:0043175	RNA polymerase core enzyme binding	1/484	42/18639	0.0238095238095238	0.916912632821724	0.66920613006812	0.805715969483856
GO:0019210	kinase inhibitor activity	2/484	90/18639	0.0222222222222222	0.855785123966942	0.682287626652112	0.820207943218848
GO:0016790	thiolester hydrolase activity	1/484	44/18639	0.0227272727272727	0.875234785875282	0.686200808048408	0.822393334836641
GO:0030547	signaling receptor inhibitor activity	1/484	44/18639	0.0227272727272727	0.875234785875282	0.686200808048408	0.822393334836641
GO:0099094	ligand-gated monoatomic cation channel activity	3/484	136/18639	0.0220588235294118	0.849492586290715	0.689634043899973	0.825248055581523
GO:0052689	carboxylic ester hydrolase activity	2/484	92/18639	0.0217391304347826	0.837181099532878	0.693894339007422	0.828387989150701
GO:0051539	4 iron, 4 sulfur cluster binding	1/484	45/18639	0.0222222222222222	0.855785123966942	0.694368531033327	0.828387989150701
GO:0004180	carboxypeptidase activity	1/484	46/18639	0.0217391304347826	0.837181099532878	0.702324088255004	0.83407626214853
GO:0030276	clathrin binding	1/484	46/18639	0.0217391304347826	0.837181099532878	0.702324088255004	0.83407626214853
GO:0030291	protein serine/threonine kinase inhibitor activity	1/484	46/18639	0.0217391304347826	0.837181099532878	0.702324088255004	0.83407626214853
GO:0008237	metallopeptidase activity	4/484	184/18639	0.0217391304347826	0.837181099532878	0.707327970151471	0.835693087220824
GO:0005504	fatty acid binding	1/484	47/18639	0.0212765957446809	0.81936873571303	0.710072979842407	0.835693087220824
GO:0043495	protein-membrane adaptor activity	1/484	47/18639	0.0212765957446809	0.81936873571303	0.710072979842407	0.835693087220824
GO:0061749	forked DNA-dependent helicase activity	1/484	47/18639	0.0212765957446809	0.81936873571303	0.710072979842407	0.835693087220824
GO:0140359	ABC-type transporter activity	1/484	47/18639	0.0212765957446809	0.81936873571303	0.710072979842407	0.835693087220824
GO:1990518	single-stranded 3'-5' DNA helicase activity	1/484	47/18639	0.0212765957446809	0.81936873571303	0.710072979842407	0.835693087220824
GO:0015078	proton transmembrane transporter activity	4/484	185/18639	0.0216216216216216	0.83265579629216	0.711311063143	0.835896982885112
GO:0015276	ligand-gated monoatomic ion channel activity	4/484	186/18639	0.021505376344086	0.828179152226073	0.715254501054105	0.83829187864374
GO:0009378	four-way junction helicase activity	1/484	48/18639	0.0208333333333333	0.802298553719008	0.717620563628781	0.83829187864374
GO:0036121	double-stranded DNA helicase activity	1/484	48/18639	0.0208333333333333	0.802298553719008	0.717620563628781	0.83829187864374
GO:0043138	3'-5' DNA helicase activity	1/484	48/18639	0.0208333333333333	0.802298553719008	0.717620563628781	0.83829187864374
GO:0022834	ligand-gated channel activity	4/484	188/18639	0.0212765957446809	0.81936873571303	0.723022594746998	0.84334730590846
GO:0015293	symporter activity	3/484	146/18639	0.0205479452054795	0.791308162572173	0.734628639495381	0.855613474783196
GO:0015085	calcium ion transmembrane transporter activity	3/484	147/18639	0.0204081632653061	0.785925113847192	0.738832164852972	0.857014750410532
GO:0005048	signal sequence binding	1/484	51/18639	0.0196078431372549	0.755104521147302	0.739106988570612	0.857014750410532
GO:0005272	sodium channel activity	1/484	51/18639	0.0196078431372549	0.755104521147302	0.739106988570612	0.857014750410532
GO:0030159	signaling receptor complex adaptor activity	1/484	52/18639	0.0192307692307692	0.740583280356008	0.745900200187344	0.861075224432581
GO:0004864	protein phosphatase inhibitor activity	1/484	53/18639	0.0188679245283019	0.726610010915328	0.752516884058293	0.861075224432581
GO:0005544	calcium-dependent phospholipid binding	1/484	53/18639	0.0188679245283019	0.726610010915328	0.752516884058293	0.861075224432581
GO:0016860	intramolecular oxidoreductase activity	1/484	53/18639	0.0188679245283019	0.726610010915328	0.752516884058293	0.861075224432581
GO:0051018	protein kinase A binding	1/484	53/18639	0.0188679245283019	0.726610010915328	0.752516884058293	0.861075224432581
GO:0140296	general transcription initiation factor binding	1/484	53/18639	0.0188679245283019	0.726610010915328	0.752516884058293	0.861075224432581
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/484	53/18639	0.0188679245283019	0.726610010915328	0.752516884058293	0.861075224432581
GO:0000510	H3-H4 histone complex chaperone activity	3/484	151/18639	0.0198675496688742	0.765105905533359	0.755120419726911	0.861075224432581
GO:0140584	chromatin extrusion motor activity	3/484	151/18639	0.0198675496688742	0.765105905533359	0.755120419726911	0.861075224432581
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	3/484	151/18639	0.0198675496688742	0.765105905533359	0.755120419726911	0.861075224432581
GO:0140849	ATP-dependent H2AZ histone chaperone activity	3/484	151/18639	0.0198675496688742	0.765105905533359	0.755120419726911	0.861075224432581
GO:0017069	snRNA binding	1/484	54/18639	0.0185185185185185	0.713154269972452	0.758961618165459	0.861075224432581
GO:0050661	NADP binding	1/484	54/18639	0.0185185185185185	0.713154269972452	0.758961618165459	0.861075224432581
GO:0015616	DNA translocase activity	3/484	152/18639	0.0197368421052632	0.760072314049587	0.759062490837384	0.861075224432581
GO:0140674	ATP-dependent histone chaperone activity	3/484	152/18639	0.0197368421052632	0.760072314049587	0.759062490837384	0.861075224432581
GO:0003774	cytoskeletal motor activity	3/484	153/18639	0.0196078431372549	0.755104521147302	0.762953189428143	0.862277547584579
GO:0061775	cohesin loader activity	3/484	153/18639	0.0196078431372549	0.755104521147302	0.762953189428143	0.862277547584579
GO:0008374	O-acyltransferase activity	1/484	55/18639	0.0181818181818182	0.700187828700225	0.765238862007693	0.862277547584579
GO:0004497	monooxygenase activity	2/484	106/18639	0.0188679245283019	0.726610010915328	0.765614586836244	0.862277547584579
GO:0008013	beta-catenin binding	2/484	106/18639	0.0188679245283019	0.726610010915328	0.765614586836244	0.862277547584579
GO:0005506	iron ion binding	3/484	154/18639	0.0194805194805195	0.750201245035956	0.766792844819183	0.862367311150514
GO:0004386	helicase activity	3/484	155/18639	0.0193548387096774	0.745361237003466	0.770581795309511	0.865017247619789
GO:0019212	phosphatase inhibitor activity	1/484	56/18639	0.0178571428571429	0.687684474616293	0.771352959660958	0.865017247619789
GO:0140658	ATP-dependent chromatin remodeler activity	3/484	158/18639	0.0189873417721519	0.731208808452767	0.781647925433847	0.874595903608986
GO:0017116	single-stranded DNA helicase activity	1/484	58/18639	0.0172413793103448	0.663971216870903	0.783108533401422	0.874595903608986
GO:0004222	metalloendopeptidase activity	2/484	110/18639	0.0181818181818182	0.700187828700225	0.783236841066391	0.874595903608986
GO:0031593	polyubiquitin modification-dependent protein binding	1/484	59/18639	0.0169491525423729	0.652717467432414	0.788758146976241	0.877041123289077
GO:0036002	pre-mRNA binding	1/484	59/18639	0.0169491525423729	0.652717467432414	0.788758146976241	0.877041123289077
GO:0003689	DNA clamp loader activity	3/484	160/18639	0.01875	0.722068698347107	0.788778386040877	0.877041123289077
GO:0005200	structural constituent of cytoskeleton	2/484	112/18639	0.0178571428571429	0.687684474616293	0.791604462698461	0.87893847697071
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/484	60/18639	0.0166666666666667	0.641838842975207	0.794260894923684	0.880642376433746
GO:0015081	sodium ion transmembrane transporter activity	3/484	164/18639	0.0182926829268293	0.704457266680105	0.802460318917218	0.886015650532195
GO:0140713	histone chaperone activity	3/484	164/18639	0.0182926829268293	0.704457266680105	0.802460318917218	0.886015650532195
GO:0035401	histone H3Y41 kinase activity	2/484	115/18639	0.0173913043478261	0.669744879626303	0.803621838444488	0.886015650532195
GO:0140801	histone H2AXY142 kinase activity	2/484	115/18639	0.0173913043478261	0.669744879626303	0.803621838444488	0.886015650532195
GO:0015179	L-amino acid transmembrane transporter activity	1/484	62/18639	0.0161290322580645	0.621134364169555	0.804840935985908	0.886115196001316
GO:0009055	electron transfer activity	2/484	116/18639	0.0172413793103448	0.663971216870903	0.807488849109414	0.887785359314972
GO:0015399	primary active transmembrane transporter activity	3/484	166/18639	0.0180722891566265	0.695969829732152	0.809018140549315	0.888222713749947
GO:0004536	DNA nuclease activity	1/484	64/18639	0.015625	0.601723915289256	0.814877969428694	0.892316347061386
GO:0022853	active monoatomic ion transmembrane transporter activity	2/484	118/18639	0.0169491525423729	0.652717467432414	0.815020153940144	0.892316347061386
GO:0016500	protein-hormone receptor activity	1/484	67/18639	0.0149253731343284	0.574781053410633	0.828975833627307	0.90507097273635
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/484	67/18639	0.0149253731343284	0.574781053410633	0.828975833627307	0.90507097273635
GO:0003823	antigen binding	3/484	174/18639	0.0172413793103448	0.663971216870903	0.833439170247848	0.908680206450779
GO:0097110	scaffold protein binding	1/484	70/18639	0.0142857142857143	0.550147579693034	0.842002131556753	0.916742958768448
GO:0140299	molecular sensor activity	1/484	71/18639	0.0140845070422535	0.542399022232569	0.846120337616666	0.919950782588758
GO:0004521	RNA endonuclease activity	1/484	73/18639	0.0136986301369863	0.527538775048115	0.854038156261697	0.925994409758885
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/484	73/18639	0.0136986301369863	0.527538775048115	0.854038156261697	0.925994409758885
GO:0003678	DNA helicase activity	1/484	74/18639	0.0135135135135135	0.5204098726826	0.857843258726921	0.927568611105482
GO:0005262	calcium channel activity	2/484	131/18639	0.0152671755725191	0.587943978297899	0.857853263264433	0.927568611105482
GO:0015297	antiporter activity	2/484	135/18639	0.0148148148148148	0.570523415977961	0.869087816815099	0.936591253027866
GO:0140597	protein carrier chaperone	3/484	188/18639	0.0159574468085106	0.614526551784772	0.869739612442517	0.936591253027866
GO:0015291	secondary active transmembrane transporter activity	5/484	287/18639	0.0174216027874564	0.670911682552481	0.869777099945624	0.936591253027866
GO:0019838	growth factor binding	2/484	136/18639	0.0147058823529412	0.566328390860476	0.87176623133622	0.937447248765661
GO:0015370	solute:sodium symporter activity	1/484	79/18639	0.0126582278481013	0.487472538968511	0.875434246480322	0.940103807779826
GO:0048306	calcium-dependent protein binding	1/484	80/18639	0.0125	0.481379132231405	0.878682620656158	0.94113984355497
GO:0140098	catalytic activity, acting on RNA	7/484	387/18639	0.0180878552971576	0.696569286949837	0.878796822071074	0.94113984355497
GO:0004713	protein tyrosine kinase activity	2/484	140/18639	0.0142857142857143	0.550147579693034	0.881983431548011	0.943265659080638
GO:0005254	chloride channel activity	1/484	83/18639	0.0120481927710843	0.463979886488101	0.887929233346274	0.948332582553504
GO:0016651	oxidoreductase activity, acting on NAD(P)H	1/484	88/18639	0.0113636363636364	0.437617392937641	0.901803650261447	0.961842208498962
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	1/484	91/18639	0.010989010989011	0.423190445917719	0.909291158613076	0.96814677773711
GO:0022804	active transmembrane transporter activity	8/484	457/18639	0.0175054704595186	0.674141454328445	0.910181301872595	0.96814677773711
GO:0008094	ATP-dependent activity, acting on DNA	3/484	210/18639	0.0142857142857143	0.550147579693034	0.912766621019255	0.969582946549547
GO:0042562	hormone binding	1/484	94/18639	0.0106382978723404	0.409684367856515	0.916208830972539	0.971924232856005
GO:0004857	enzyme inhibitor activity	7/484	416/18639	0.0168269230769231	0.648010370311507	0.918079466119454	0.972024762103043
GO:0022836	gated channel activity	5/484	318/18639	0.0157232704402516	0.60550834242944	0.918780093605679	0.972024762103043
GO:0030594	neurotransmitter receptor activity	1/484	97/18639	0.0103092783505155	0.397013717304252	0.922599951716176	0.972958377051042
GO:0015079	potassium ion transmembrane transporter activity	2/484	160/18639	0.0125	0.481379132231405	0.922665698703843	0.972958377051042
GO:0004866	endopeptidase inhibitor activity	2/484	161/18639	0.0124223602484472	0.478389199733073	0.924305887901096	0.972958377051042
GO:0005249	voltage-gated potassium channel activity	1/484	98/18639	0.0102040816326531	0.392962556923596	0.924620317554239	0.972958377051042
GO:0008017	microtubule binding	4/484	276/18639	0.0144927536231884	0.558120733021919	0.930534511716321	0.976574132766664
GO:0015103	inorganic anion transmembrane transporter activity	2/484	165/18639	0.0121212121212121	0.46679188580015	0.930544523961101	0.976574132766664
GO:0015171	amino acid transmembrane transporter activity	1/484	102/18639	0.00980392156862745	0.377552260573651	0.932188974446072	0.976993784966845
GO:0005253	monoatomic anion channel activity	1/484	103/18639	0.00970873786407767	0.373886704645751	0.933959516409071	0.977544293841494
GO:0030414	peptidase inhibitor activity	2/484	169/18639	0.0118343195266272	0.455743557142159	0.936295303538758	0.978684172141046
GO:0140097	catalytic activity, acting on DNA	5/484	336/18639	0.0148809523809524	0.573070395513577	0.939066205975003	0.980275228311672
GO:0004620	phospholipase activity	1/484	109/18639	0.00917431192660551	0.353305785123967	0.943654836362823	0.98289772395046
GO:0022832	voltage-gated channel activity	2/484	175/18639	0.0114285714285714	0.440118063754427	0.944082654597002	0.98289772395046
GO:0046873	metal ion transmembrane transporter activity	7/484	450/18639	0.0155555555555556	0.599049586776859	0.949690975667443	0.987427040925752
GO:0004175	endopeptidase activity	6/484	405/18639	0.0148148148148148	0.570523415977961	0.953881531698983	0.989234901047075
GO:0046943	carboxylic acid transmembrane transporter activity	2/484	188/18639	0.0106382978723404	0.409684367856515	0.957964241273614	0.989234901047075
GO:0042277	peptide binding	3/484	249/18639	0.0120481927710843	0.463979886488101	0.958691123936898	0.989234901047075
GO:0140104	molecular carrier activity	3/484	249/18639	0.0120481927710843	0.463979886488101	0.958691123936898	0.989234901047075
GO:0005342	organic acid transmembrane transporter activity	2/484	189/18639	0.0105820105820106	0.407516725698544	0.95888317084801	0.989234901047075
GO:0015108	chloride transmembrane transporter activity	1/484	121/18639	0.00826446280991736	0.318267194863739	0.958990776683852	0.989234901047075
GO:0005267	potassium channel activity	1/484	124/18639	0.00806451612903226	0.310567182084777	0.962123171072255	0.990968944866624
GO:0008236	serine-type peptidase activity	2/484	194/18639	0.0103092783505155	0.397013717304252	0.963196566793928	0.990968944866624
GO:0017171	serine hydrolase activity	2/484	198/18639	0.0101010101010101	0.388993238166792	0.966331349315683	0.991210053430383
GO:0016298	lipase activity	1/484	130/18639	0.00769230769230769	0.296233312142403	0.967689718033641	0.991210053430383
GO:0003730	mRNA 3'-UTR binding	3/484	262/18639	0.0114503816793893	0.440957983723424	0.968084939775701	0.991210053430383
GO:0016757	glycosyltransferase activity	3/484	267/18639	0.0112359550561798	0.432700343578791	0.971129901918679	0.991210053430383
GO:0008514	organic anion transmembrane transporter activity	3/484	269/18639	0.0111524163568773	0.429483240652555	0.972269243692979	0.991210053430383
GO:0005516	calmodulin binding	2/484	207/18639	0.00966183574879227	0.372080488681279	0.972473801534415	0.991210053430383
GO:0140101	catalytic activity, acting on a tRNA	1/484	139/18639	0.00719424460431655	0.277052737974909	0.974546417222046	0.991210053430383
GO:0020037	heme binding	1/484	142/18639	0.00704225352112676	0.271199511116284	0.976492471937144	0.991210053430383
GO:0005216	monoatomic ion channel activity	6/484	448/18639	0.0133928571428571	0.51576335596222	0.977005367552036	0.991210053430383
GO:0022843	voltage-gated monoatomic cation channel activity	1/484	143/18639	0.00699300699300699	0.269303011038548	0.977107579445519	0.991210053430383
GO:0008194	UDP-glycosyltransferase activity	1/484	145/18639	0.00689655172413793	0.265588486748361	0.97829002477652	0.991210053430383
GO:0005261	monoatomic cation channel activity	4/484	341/18639	0.0117302052785924	0.451734083032403	0.97858317376885	0.991210053430383
GO:0008509	monoatomic anion transmembrane transporter activity	1/484	149/18639	0.00671140939597315	0.25845859448666	0.980475182690215	0.991846673211107
GO:0046906	tetrapyrrole binding	1/484	152/18639	0.00657894736842105	0.253357438016529	0.981968739461833	0.992079099713692
GO:0008083	growth factor activity	1/484	162/18639	0.00617283950617284	0.237718089990817	0.986171277524557	0.995044283877606
GO:0005539	glycosaminoglycan binding	2/484	242/18639	0.00826446280991736	0.318267194863739	0.987588499749744	0.995195086397367
GO:0005244	voltage-gated monoatomic ion channel activity	1/484	173/18639	0.00578034682080925	0.222603066927817	0.989673798247101	0.995537506274737
GO:0004252	serine-type endopeptidase activity	1/484	176/18639	0.00568181818181818	0.21880869646882	0.990464703694994	0.995537506274737
GO:0016758	hexosyltransferase activity	1/484	197/18639	0.0050761421319797	0.195483911566053	0.994543305598733	0.998358689124048
GO:0030371	translation repressor activity	2/484	329/18639	0.0060790273556231	0.234105353060866	0.998400963460733	0.999317481725815
GO:0045182	translation regulator activity	2/484	356/18639	0.00561797752808989	0.216350171789396	0.999166272966723	0.999317481725815
GO:1901681	sulfur compound binding	1/484	275/18639	0.00363636363636364	0.140037565740045	0.999317481725815	0.999317481725815