ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0140375 immune receptor activity 16/260 156/18639 0.102564102564103 7.35266272189349 6.02642565229398e-10 3.63996109398557e-07 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 5/260 16/18639 0.3125 22.4026442307692 1.95774113740008e-06 0.000591237823494824 GO:0004896 cytokine receptor activity 9/260 96/18639 0.09375 6.72079326923077 7.84305373751265e-06 0.00157906815248588 GO:0140313 molecular sequestering activity 7/260 55/18639 0.127272727272727 9.12398601398601 1.08650393968788e-05 0.00164062094892869 GO:0035325 Toll-like receptor binding 4/260 13/18639 0.307692307692308 22.0579881656805 2.39585427548034e-05 0.00289419196478025 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 5/260 39/18639 0.128205128205128 9.19082840236686 0.000198559363620696 0.0199883092711501 GO:0003953 NAD+ nucleosidase activity 3/260 11/18639 0.272727272727273 19.5513986013986 0.000407512003650966 0.0273485833561315 GO:0019864 IgG binding 3/260 11/18639 0.272727272727273 19.5513986013986 0.000407512003650966 0.0273485833561315 GO:0050786 RAGE receptor binding 3/260 11/18639 0.272727272727273 19.5513986013986 0.000407512003650966 0.0273485833561315 GO:0044389 ubiquitin-like protein ligase binding 13/260 322/18639 0.0403726708074534 2.89425465838509 0.000622193842142436 0.0375805080654031 GO:0004857 enzyme inhibitor activity 15/260 416/18639 0.0360576923076923 2.58492048816568 0.000784005818150908 0.0404065793498718 GO:0003924 GTPase activity 13/260 331/18639 0.0392749244712991 2.81555891238671 0.000802779722182884 0.0404065793498718 GO:0019763 immunoglobulin receptor activity 3/260 14/18639 0.214285714285714 15.3618131868132 0.000871551603431661 0.0404936283440556 GO:0019955 cytokine binding 8/260 144/18639 0.0555555555555556 3.98269230769231 0.000947642853750995 0.0408840202618287 GO:0043015 gamma-tubulin binding 4/260 35/18639 0.114285714285714 8.19296703296703 0.00137867019981077 0.0555144533790471 GO:0036041 long-chain fatty acid binding 3/260 17/18639 0.176470588235294 12.6509049773756 0.00157856811323802 0.0595909462747352 GO:0001217 DNA-binding transcription repressor activity 11/260 278/18639 0.039568345323741 2.83659380188157 0.00188440745289613 0.0669518883264271 GO:0061659 ubiquitin-like protein ligase activity 13/260 372/18639 0.0349462365591398 2.50524193548387 0.00227811413522668 0.0754358086039301 GO:0019207 kinase regulator activity 11/260 287/18639 0.0383275261324042 2.74764138300724 0.00241431484118983 0.0754358086039301 GO:0001530 lipopolysaccharide binding 4/260 41/18639 0.0975609756097561 6.99399624765478 0.00249787445708378 0.0754358086039301 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/260 21/18639 0.142857142857143 10.2412087912088 0.00296300703338395 0.0815047198977875 GO:0019787 ubiquitin-like protein transferase activity 15/260 479/18639 0.0313152400835073 2.2449413842942 0.00309802565216717 0.0815047198977875 GO:0070851 growth factor receptor binding 7/260 139/18639 0.0503597122302158 3.61021029330382 0.0033975881590623 0.0815047198977875 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 12/260 349/18639 0.0343839541547278 2.46493277496143 0.00378129758526335 0.0815047198977875 GO:0003725 double-stranded RNA binding 5/260 75/18639 0.0666666666666667 4.77923076923077 0.00396463384422309 0.0815047198977875 GO:0001784 phosphotyrosine residue binding 4/260 47/18639 0.0851063829787234 6.10114566284779 0.0041220085027538 0.0815047198977875 GO:0061630 ubiquitin protein ligase activity 12/260 353/18639 0.0339943342776204 2.43700152538679 0.00413889520308267 0.0815047198977875 GO:0016755 aminoacyltransferase activity 15/260 496/18639 0.030241935483871 2.16799782878412 0.00427528747795103 0.0815047198977875 GO:0004842 ubiquitin-protein transferase activity 14/260 449/18639 0.0311804008908686 2.23527497001885 0.00437323723348059 0.0815047198977875 GO:0038187 pattern recognition receptor activity 4/260 48/18639 0.0833333333333333 5.97403846153846 0.0044482610042621 0.0815047198977875 GO:0042578 phosphoric ester hydrolase activity 12/260 363/18639 0.0330578512396694 2.36986649713922 0.0051527493782024 0.0815047198977875 GO:0048306 calcium-dependent protein binding 5/260 80/18639 0.0625 4.48052884615385 0.00522125043052152 0.0815047198977875 GO:0000510 H3-H4 histone complex chaperone activity 7/260 151/18639 0.0463576158940397 3.32330616403464 0.00533962807613316 0.0815047198977875 GO:0140584 chromatin extrusion motor activity 7/260 151/18639 0.0463576158940397 3.32330616403464 0.00533962807613316 0.0815047198977875 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 7/260 151/18639 0.0463576158940397 3.32330616403464 0.00533962807613316 0.0815047198977875 GO:0140849 ATP-dependent H2AZ histone chaperone activity 7/260 151/18639 0.0463576158940397 3.32330616403464 0.00533962807613316 0.0815047198977875 GO:0005126 cytokine receptor binding 10/260 275/18639 0.0363636363636364 2.60685314685315 0.00541172280669277 0.0815047198977875 GO:0019865 immunoglobulin binding 3/260 26/18639 0.115384615384615 8.27174556213018 0.00550278526978302 0.0815047198977875 GO:0001221 transcription coregulator binding 6/260 115/18639 0.0521739130434783 3.74026755852843 0.00552128418240991 0.0815047198977875 GO:0015616 DNA translocase activity 7/260 152/18639 0.0460526315789474 3.30144230769231 0.00553260515862465 0.0815047198977875 GO:0140674 ATP-dependent histone chaperone activity 7/260 152/18639 0.0460526315789474 3.30144230769231 0.00553260515862465 0.0815047198977875 GO:0061775 cohesin loader activity 7/260 153/18639 0.0457516339869281 3.27986425339367 0.00573076332625478 0.0824138345013782 GO:0019208 phosphatase regulator activity 6/260 117/18639 0.0512820512820513 3.67633136094675 0.00599823253139668 0.0842542429991533 GO:0046625 sphingolipid binding 3/260 28/18639 0.107142857142857 7.68090659340659 0.00679307377121959 0.0913009710452656 GO:0140658 ATP-dependent chromatin remodeler activity 7/260 158/18639 0.0443037974683544 3.17607108081792 0.00680222466396847 0.0913009710452656 GO:0003689 DNA clamp loader activity 7/260 160/18639 0.04375 3.13637019230769 0.00727003389321399 0.0937393773235054 GO:0045296 cadherin binding 11/260 334/18639 0.0329341317365269 2.36099723629664 0.00745969628209748 0.0937393773235054 GO:0051861 glycolipid binding 3/260 29/18639 0.103448275862069 7.41604774535809 0.00749984566048775 0.0937393773235054 GO:0043208 glycosphingolipid binding 2/260 10/18639 0.2 14.3376923076923 0.00810173525060112 0.0937393773235054 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 5/260 89/18639 0.0561797752808989 4.02744165946413 0.00815211996344002 0.0937393773235054 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 5/260 89/18639 0.0561797752808989 4.02744165946413 0.00815211996344002 0.0937393773235054 GO:0048019 receptor antagonist activity 3/260 30/18639 0.1 7.16884615384615 0.00824848766902243 0.0937393773235054 GO:0140713 histone chaperone activity 7/260 164/18639 0.0426829268292683 3.05987335834897 0.00827661649884381 0.0937393773235054 GO:0019210 kinase inhibitor activity 5/260 90/18639 0.0555555555555556 3.98269230769231 0.00853587045164371 0.0937393773235054 GO:0140793 histone H2AXY142 phosphatase activity 5/260 90/18639 0.0555555555555556 3.98269230769231 0.00853587045164371 0.0937393773235054 GO:0045309 protein phosphorylated amino acid binding 4/260 59/18639 0.0677966101694915 4.86023468057366 0.00923839007403456 0.0996426357985156 GO:0051219 phosphoprotein binding 5/260 93/18639 0.0537634408602151 3.85421836228288 0.00976183469222798 0.102175583342114 GO:0140031 phosphorylation-dependent protein binding 2/260 11/18639 0.181818181818182 13.0342657342657 0.00981156263881228 0.102175583342114 GO:0031625 ubiquitin protein ligase binding 10/260 302/18639 0.033112582781457 2.3737901171676 0.0101435020817356 0.103841953514717 GO:0015026 coreceptor activity 4/260 61/18639 0.0655737704918033 4.70088272383354 0.0103671153597062 0.104362294621042 GO:0019239 deaminase activity 3/260 33/18639 0.0909090909090909 6.51713286713287 0.0107506638176507 0.104732273320339 GO:0140311 protein sequestering activity 3/260 33/18639 0.0909090909090909 6.51713286713287 0.0107506638176507 0.104732273320339 GO:0004875 complement receptor activity 2/260 12/18639 0.166666666666667 11.9480769230769 0.0116663233234581 0.106764534657102 GO:0005095 GTPase inhibitor activity 2/260 12/18639 0.166666666666667 11.9480769230769 0.0116663233234581 0.106764534657102 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/260 12/18639 0.166666666666667 11.9480769230769 0.0116663233234581 0.106764534657102 GO:0097677 STAT family protein binding 2/260 12/18639 0.166666666666667 11.9480769230769 0.0116663233234581 0.106764534657102 GO:0004725 protein tyrosine phosphatase activity 5/260 98/18639 0.0510204081632653 3.65757456828885 0.0120650763218811 0.107767977218471 GO:0002020 protease binding 6/260 136/18639 0.0441176470588235 3.16272624434389 0.012132818627245 0.107767977218471 GO:0000175 3'-5'-RNA exonuclease activity 3/260 35/18639 0.0857142857142857 6.14472527472527 0.0126365437147733 0.110615542082943 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 9/260 268/18639 0.0335820895522388 2.40744833524684 0.0132175257684605 0.113036309140144 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/260 36/18639 0.0833333333333333 5.97403846153846 0.0136458486803673 0.113036309140144 GO:0032396 inhibitory MHC class I receptor activity 2/260 13/18639 0.153846153846154 11.0289940828402 0.0136616731245538 0.113036309140144 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/260 13/18639 0.153846153846154 11.0289940828402 0.0136616731245538 0.113036309140144 GO:0019903 protein phosphatase binding 6/260 144/18639 0.0416666666666667 2.98701923076923 0.0157084783430777 0.127230617866527 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 3/260 38/18639 0.0789473684210526 5.65961538461538 0.0157985038741548 0.127230617866527 GO:0140597 protein carrier chaperone 7/260 188/18639 0.0372340425531915 2.66925122749591 0.0165827732897126 0.131789408776137 GO:0019888 protein phosphatase regulator activity 5/260 107/18639 0.0467289719626168 3.3499281092739 0.0170905707641189 0.134061100539322 GO:0005525 GTP binding 11/260 378/18639 0.0291005291005291 2.08617216117216 0.0174897758499908 0.135433648889672 GO:0050700 CARD domain binding 2/260 15/18639 0.133333333333333 9.55846153846154 0.0180572225590746 0.136890495273782 GO:0004532 RNA exonuclease activity 3/260 40/18639 0.075 5.37663461538462 0.0181311914269909 0.136890495273782 GO:0015631 tubulin binding 11/260 385/18639 0.0285714285714286 2.04824175824176 0.0197332433483732 0.146285824746153 GO:0140297 DNA-binding transcription factor binding 13/260 488/18639 0.0266393442622951 1.90973360655738 0.0199245874043077 0.146285824746153 GO:0005149 interleukin-1 receptor binding 2/260 16/18639 0.125 8.96105769230769 0.0204491879342963 0.146285824746153 GO:0016722 oxidoreductase activity, acting on metal ions 2/260 16/18639 0.125 8.96105769230769 0.0204491879342963 0.146285824746153 GO:0035198 miRNA binding 3/260 42/18639 0.0714285714285714 5.1206043956044 0.0206449728988129 0.146285824746153 GO:0001216 DNA-binding transcription activator activity 13/260 491/18639 0.0264765784114053 1.89806517311609 0.020828776371141 0.146285824746153 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/260 17/18639 0.117647058823529 8.43393665158371 0.022965270577104 0.156639809562155 GO:0019198 transmembrane receptor protein phosphatase activity 2/260 17/18639 0.117647058823529 8.43393665158371 0.022965270577104 0.156639809562155 GO:0001046 core promoter sequence-specific DNA binding 3/260 44/18639 0.0681818181818182 4.88784965034965 0.0233403689744933 0.156639809562155 GO:0030547 signaling receptor inhibitor activity 3/260 44/18639 0.0681818181818182 4.88784965034965 0.0233403689744933 0.156639809562155 GO:0046332 SMAD binding 4/260 79/18639 0.0506329113924051 3.62979552093476 0.0246118364002958 0.161076547168868 GO:0004715 non-membrane spanning protein tyrosine kinase activity 3/260 45/18639 0.0666666666666667 4.77923076923077 0.0247561967619999 0.161076547168868 GO:0019001 guanyl nucleotide binding 11/260 400/18639 0.0275 1.97143269230769 0.0252489597897221 0.161076547168868 GO:0032561 guanyl ribonucleotide binding 11/260 400/18639 0.0275 1.97143269230769 0.0252489597897221 0.161076547168868 GO:0017128 phospholipid scramblase activity 2/260 18/18639 0.111111111111111 7.96538461538462 0.025601570410946 0.161076547168868 GO:0032393 MHC class I receptor activity 2/260 18/18639 0.111111111111111 7.96538461538462 0.025601570410946 0.161076547168868 GO:0032182 ubiquitin-like protein binding 5/260 120/18639 0.0416666666666667 2.98701923076923 0.0265362365520169 0.164424126812122 GO:0001618 virus receptor activity 4/260 81/18639 0.0493827160493827 3.54017094017094 0.0266780868006424 0.164424126812122 GO:0019887 protein kinase regulator activity 8/260 255/18639 0.0313725490196078 2.24904977375566 0.0270788074353207 0.165208077686199 GO:0005504 fatty acid binding 3/260 47/18639 0.0638297872340425 4.57585924713584 0.0277239015301554 0.165944630280667 GO:0140272 exogenous protein binding 4/260 82/18639 0.0487804878048781 3.49699812382739 0.0277490193018996 0.165944630280667 GO:0008094 ATP-dependent activity, acting on DNA 7/260 210/18639 0.0333333333333333 2.38961538461538 0.0282682753289309 0.167392532339944 GO:0004860 protein kinase inhibitor activity 4/260 84/18639 0.0476190476190476 3.41373626373626 0.0299669697892716 0.175728638375923 GO:0008081 phosphoric diester hydrolase activity 4/260 87/18639 0.0459770114942529 3.29602122015915 0.0334852553119581 0.194043318784049 GO:0031490 chromatin DNA binding 5/260 128/18639 0.0390625 2.80033052884615 0.0337326961462337 0.194043318784049 GO:0016798 hydrolase activity, acting on glycosyl bonds 5/260 130/18639 0.0384615384615385 2.75724852071006 0.0357034111608028 0.202983740404453 GO:0003727 single-stranded RNA binding 4/260 89/18639 0.0449438202247191 3.22195332757131 0.0359590401047624 0.202983740404453 GO:0004721 phosphoprotein phosphatase activity 6/260 175/18639 0.0342857142857143 2.45789010989011 0.036329034642774 0.203173490039217 GO:0016791 phosphatase activity 8/260 273/18639 0.0293040293040293 2.10076077768385 0.0381972101961119 0.211661605123409 GO:0140463 chromatin-protein adaptor activity 3/260 54/18639 0.0555555555555556 3.98269230769231 0.0395265914752937 0.215601142798794 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 12/260 484/18639 0.0247933884297521 1.77739987285442 0.0396220643222949 0.215601142798794 GO:0016493 C-C chemokine receptor activity 2/260 23/18639 0.0869565217391304 6.23377926421405 0.0404556122506459 0.216240617693718 GO:0031681 G-protein beta-subunit binding 2/260 23/18639 0.0869565217391304 6.23377926421405 0.0404556122506459 0.216240617693718 GO:0098632 cell-cell adhesion mediator activity 3/260 55/18639 0.0545454545454545 3.91027972027972 0.0413899600920487 0.219294174522784 GO:0140789 histone phosphatase activity 5/260 136/18639 0.0367647058823529 2.63560520361991 0.0420354388546384 0.220777435375666 GO:0019957 C-C chemokine binding 2/260 24/18639 0.0833333333333333 5.97403846153846 0.0437359050100573 0.225781936974997 GO:0035035 histone acetyltransferase binding 2/260 24/18639 0.0833333333333333 5.97403846153846 0.0437359050100573 0.225781936974997 GO:0008408 3'-5' exonuclease activity 3/260 58/18639 0.0517241379310345 3.70802387267905 0.0472403096552074 0.239774344804582 GO:0061980 regulatory RNA binding 3/260 58/18639 0.0517241379310345 3.70802387267905 0.0472403096552074 0.239774344804582 GO:0001637 G protein-coupled chemoattractant receptor activity 2/260 26/18639 0.0769230769230769 5.51449704142012 0.0505787610745464 0.240836482213346 GO:0004435 phosphatidylinositol phospholipase C activity 2/260 26/18639 0.0769230769230769 5.51449704142012 0.0505787610745464 0.240836482213346 GO:0004950 chemokine receptor activity 2/260 26/18639 0.0769230769230769 5.51449704142012 0.0505787610745464 0.240836482213346 GO:0005160 transforming growth factor beta receptor binding 2/260 26/18639 0.0769230769230769 5.51449704142012 0.0505787610745464 0.240836482213346 GO:0008157 protein phosphatase 1 binding 2/260 26/18639 0.0769230769230769 5.51449704142012 0.0505787610745464 0.240836482213346 GO:0030247 polysaccharide binding 2/260 26/18639 0.0769230769230769 5.51449704142012 0.0505787610745464 0.240836482213346 GO:0043548 phosphatidylinositol 3-kinase binding 2/260 26/18639 0.0769230769230769 5.51449704142012 0.0505787610745464 0.240836482213346 GO:0019902 phosphatase binding 6/260 190/18639 0.0315789473684211 2.26384615384615 0.0506394590084354 0.240836482213346 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/260 60/18639 0.05 3.58442307692308 0.0513542284400751 0.242327765451604 GO:0008266 poly(U) RNA binding 2/260 27/18639 0.0740740740740741 5.31025641025641 0.0541348542820742 0.251518861433637 GO:0035255 ionotropic glutamate receptor binding 2/260 27/18639 0.0740740740740741 5.31025641025641 0.0541348542820742 0.251518861433637 GO:0046875 ephrin receptor binding 2/260 28/18639 0.0714285714285714 5.1206043956044 0.0577765297059861 0.266389495743631 GO:0140104 molecular carrier activity 7/260 249/18639 0.0281124497991968 2.01533827618165 0.0606356493528399 0.277454031887237 GO:0004629 phospholipase C activity 2/260 29/18639 0.0689655172413793 4.94403183023873 0.0615007285241712 0.279296541568417 GO:0008187 poly-pyrimidine tract binding 2/260 30/18639 0.0666666666666667 4.77923076923077 0.0653044600138247 0.29217699146926 GO:0031624 ubiquitin conjugating enzyme binding 2/260 30/18639 0.0666666666666667 4.77923076923077 0.0653044600138247 0.29217699146926 GO:0005164 tumor necrosis factor receptor binding 2/260 31/18639 0.0645161290322581 4.62506203473945 0.0691848002589025 0.306209426840159 GO:0030145 manganese ion binding 3/260 68/18639 0.0441176470588235 3.16272624434389 0.0694547872137447 0.306209426840159 GO:0005200 structural constituent of cytoskeleton 4/260 112/18639 0.0357142857142857 2.5603021978022 0.0717776876629033 0.314157415568069 GO:0030515 snoRNA binding 2/260 32/18639 0.0625 4.48052884615385 0.073138890880163 0.315542072082989 GO:0070717 poly-purine tract binding 2/260 32/18639 0.0625 4.48052884615385 0.073138890880163 0.315542072082989 GO:0097110 scaffold protein binding 3/260 70/18639 0.0428571428571429 3.07236263736264 0.074374248303355 0.31598997986277 GO:0004866 endopeptidase inhibitor activity 5/260 161/18639 0.031055900621118 2.2263497372193 0.0753061902853053 0.31598997986277 GO:0005178 integrin binding 5/260 161/18639 0.031055900621118 2.2263497372193 0.0753061902853053 0.31598997986277 GO:0019956 chemokine binding 2/260 33/18639 0.0606060606060606 4.34475524475525 0.0771639377874219 0.31598997986277 GO:0071889 14-3-3 protein binding 2/260 33/18639 0.0606060606060606 4.34475524475525 0.0771639377874219 0.31598997986277 GO:0017124 SH3 domain binding 4/260 115/18639 0.0347826086956522 2.49351170568562 0.077428008310745 0.31598997986277 GO:0035401 histone H3Y41 kinase activity 4/260 115/18639 0.0347826086956522 2.49351170568562 0.077428008310745 0.31598997986277 GO:0140801 histone H2AXY142 kinase activity 4/260 115/18639 0.0347826086956522 2.49351170568562 0.077428008310745 0.31598997986277 GO:0042379 chemokine receptor binding 3/260 72/18639 0.0416666666666667 2.98701923076923 0.0794440570996482 0.322041681128775 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/260 34/18639 0.0588235294117647 4.21696832579186 0.0812572099536498 0.325261051516582 GO:1990782 protein tyrosine kinase binding 4/260 117/18639 0.0341880341880342 2.4508875739645 0.0813152628791455 0.325261051516582 GO:0005154 epidermal growth factor receptor binding 2/260 35/18639 0.0571428571428571 4.09648351648352 0.0854160382105514 0.337197954765837 GO:0061631 ubiquitin conjugating enzyme activity 2/260 35/18639 0.0571428571428571 4.09648351648352 0.0854160382105514 0.337197954765837 GO:0030414 peptidase inhibitor activity 5/260 169/18639 0.029585798816568 2.1209604005462 0.0882810137327376 0.344122516759726 GO:0004540 RNA nuclease activity 4/260 121/18639 0.0330578512396694 2.36986649713922 0.0893731226741401 0.344122516759726 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/260 36/18639 0.0555555555555556 3.98269230769231 0.089637814065268 0.344122516759726 GO:0055106 ubiquitin-protein transferase regulator activity 2/260 36/18639 0.0555555555555556 3.98269230769231 0.089637814065268 0.344122516759726 GO:0098631 cell adhesion mediator activity 3/260 76/18639 0.0394736842105263 2.82980769230769 0.0900188040530409 0.344122516759726 GO:0008017 microtubule binding 7/260 276/18639 0.0253623188405797 1.8181856187291 0.0926334570778269 0.350131805813551 GO:0003724 RNA helicase activity 3/260 77/18639 0.038961038961039 2.79305694305694 0.0927501472353776 0.350131805813551 GO:0043394 proteoglycan binding 2/260 37/18639 0.0540540540540541 3.87505197505198 0.0939199885378523 0.352345795508465 GO:0030246 carbohydrate binding 7/260 280/18639 0.025 1.79221153846154 0.0980495147684054 0.362084483169532 GO:0008186 ATP-dependent activity, acting on RNA 3/260 79/18639 0.0379746835443038 2.72234664070107 0.0983143298672239 0.362084483169532 GO:0033293 monocarboxylic acid binding 3/260 79/18639 0.0379746835443038 2.72234664070107 0.0983143298672239 0.362084483169532 GO:0140097 catalytic activity, acting on DNA 8/260 336/18639 0.0238095238095238 1.70686813186813 0.0993836850794805 0.36380451992731 GO:0035591 signaling adaptor activity 4/260 129/18639 0.0310077519379845 2.22289803220036 0.106583230527474 0.387371178196214 GO:0015144 carbohydrate transmembrane transporter activity 2/260 40/18639 0.05 3.58442307692308 0.107104282713191 0.387371178196214 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4/260 130/18639 0.0307692307692308 2.20579881656805 0.108833383523242 0.388890096371533 GO:0001540 amyloid-beta binding 3/260 83/18639 0.036144578313253 2.59114921223355 0.109833529688765 0.388890096371533 GO:0030165 PDZ domain binding 3/260 83/18639 0.036144578313253 2.59114921223355 0.109833529688765 0.388890096371533 GO:0005125 cytokine activity 6/260 234/18639 0.0256410256410256 1.83816568047337 0.110100535834657 0.388890096371533 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/260 41/18639 0.0487804878048781 3.49699812382739 0.111603712561998 0.388890096371533 GO:0004527 exonuclease activity 3/260 84/18639 0.0357142857142857 2.5603021978022 0.112791550425784 0.388890096371533 GO:0061135 endopeptidase regulator activity 5/260 184/18639 0.0271739130434783 1.94805602006689 0.115504033886054 0.388890096371533 GO:0019894 kinesin binding 2/260 42/18639 0.0476190476190476 3.41373626373626 0.116151649545158 0.388890096371533 GO:0016209 antioxidant activity 3/260 86/18639 0.0348837209302326 2.5007602862254 0.118797562113578 0.388890096371533 GO:0019838 growth factor binding 4/260 136/18639 0.0294117647058824 2.10848416289593 0.122773929312361 0.388890096371533 GO:0141003 histone H2AX kinase activity 8/260 354/18639 0.0225988700564972 1.62007822685789 0.123472391051196 0.388890096371533 GO:0005539 glycosaminoglycan binding 6/260 242/18639 0.0247933884297521 1.77739987285442 0.123638369145962 0.388890096371533 GO:0004197 cysteine-type endopeptidase activity 3/260 88/18639 0.0340909090909091 2.44392482517482 0.124919788072296 0.388890096371533 GO:0001223 transcription coactivator binding 2/260 44/18639 0.0454545454545455 3.25856643356643 0.125384236062424 0.388890096371533 GO:0140996 histone H3 kinase activity 8/260 357/18639 0.0224089635854342 1.60646412411118 0.12776334817262 0.388890096371533 GO:0008009 chemokine activity 2/260 45/18639 0.0444444444444444 3.18615384615385 0.130064609983374 0.388890096371533 GO:0140303 intramembrane lipid transporter activity 2/260 45/18639 0.0444444444444444 3.18615384615385 0.130064609983374 0.388890096371533 GO:0016887 ATP hydrolysis activity 9/260 417/18639 0.0215827338129496 1.54723298284449 0.130539117602548 0.388890096371533 GO:0005345 purine nucleobase transmembrane transporter activity 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0005381 iron ion transmembrane transporter activity 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0005522 profilin binding 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0008190 eukaryotic initiation factor 4E binding 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0030957 Tat protein binding 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0031434 mitogen-activated protein kinase kinase binding 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0035374 chondroitin sulfate binding 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0043422 protein kinase B binding 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0050308 sugar-phosphatase activity 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0070513 death domain binding 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0071723 lipopeptide binding 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:1990757 ubiquitin ligase activator activity 1/260 10/18639 0.1 7.16884615384615 0.131083875849001 0.388890096371533 GO:0035173 histone kinase activity 8/260 360/18639 0.0222222222222222 1.59307692307692 0.132131228586237 0.388890096371533 GO:0004713 protein tyrosine kinase activity 4/260 140/18639 0.0285714285714286 2.04824175824176 0.132469926526215 0.388890096371533 GO:0052689 carboxylic ester hydrolase activity 3/260 92/18639 0.0326086956521739 2.33766722408027 0.137494787359151 0.388890096371533 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0001851 complement component C3b binding 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0005114 type II transforming growth factor beta receptor binding 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0005536 D-glucose binding 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0008199 ferric iron binding 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0015205 nucleobase transmembrane transporter activity 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0019203 carbohydrate phosphatase activity 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0034511 U3 snoRNA binding 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0034713 type I transforming growth factor beta receptor binding 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0047676 arachidonate-CoA ligase activity 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0050998 nitric-oxide synthase binding 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0140537 transcription regulator activator activity 1/260 11/18639 0.0909090909090909 6.51713286713287 0.14321110717002 0.388890096371533 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/260 48/18639 0.0416666666666667 2.98701923076923 0.144337449362108 0.388890096371533 GO:0140693 molecular condensate scaffold activity 2/260 48/18639 0.0416666666666667 2.98701923076923 0.144337449362108 0.388890096371533 GO:0046982 protein heterodimerization activity 8/260 369/18639 0.021680216802168 1.55422138836773 0.145687395925449 0.388890096371533 GO:0001222 transcription corepressor binding 2/260 49/18639 0.0408163265306122 2.92605965463108 0.149165749224779 0.388890096371533 GO:0016763 pentosyltransferase activity 2/260 49/18639 0.0408163265306122 2.92605965463108 0.149165749224779 0.388890096371533 GO:0035254 glutamate receptor binding 2/260 49/18639 0.0408163265306122 2.92605965463108 0.149165749224779 0.388890096371533 GO:0051020 GTPase binding 7/260 315/18639 0.0222222222222222 1.59307692307692 0.152504142736653 0.388890096371533 GO:0032813 tumor necrosis factor receptor superfamily binding 2/260 50/18639 0.04 2.86753846153846 0.15402623342444 0.388890096371533 GO:0004000 adenosine deaminase activity 1/260 12/18639 0.0833333333333333 5.97403846153846 0.155169723883343 0.388890096371533 GO:0004126 cytidine deaminase activity 1/260 12/18639 0.0833333333333333 5.97403846153846 0.155169723883343 0.388890096371533 GO:0004859 phospholipase inhibitor activity 1/260 12/18639 0.0833333333333333 5.97403846153846 0.155169723883343 0.388890096371533 GO:0008179 adenylate cyclase binding 1/260 12/18639 0.0833333333333333 5.97403846153846 0.155169723883343 0.388890096371533 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/260 12/18639 0.0833333333333333 5.97403846153846 0.155169723883343 0.388890096371533 GO:0015166 polyol transmembrane transporter activity 1/260 12/18639 0.0833333333333333 5.97403846153846 0.155169723883343 0.388890096371533 GO:0035251 UDP-glucosyltransferase activity 1/260 12/18639 0.0833333333333333 5.97403846153846 0.155169723883343 0.388890096371533 GO:0035259 nuclear glucocorticoid receptor binding 1/260 12/18639 0.0833333333333333 5.97403846153846 0.155169723883343 0.388890096371533 GO:0070008 serine-type exopeptidase activity 1/260 12/18639 0.0833333333333333 5.97403846153846 0.155169723883343 0.388890096371533 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/260 12/18639 0.0833333333333333 5.97403846153846 0.155169723883343 0.388890096371533 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/260 12/18639 0.0833333333333333 5.97403846153846 0.155169723883343 0.388890096371533 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/260 12/18639 0.0833333333333333 5.97403846153846 0.155169723883343 0.388890096371533 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/260 12/18639 0.0833333333333333 5.97403846153846 0.155169723883343 0.388890096371533 GO:0005080 protein kinase C binding 2/260 52/18639 0.0384615384615385 2.75724852071006 0.163836491093386 0.402943780947059 GO:0043130 ubiquitin binding 3/260 100/18639 0.03 2.15065384615385 0.163839775851965 0.402943780947059 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/260 13/18639 0.0769230769230769 5.51449704142012 0.166962061446576 0.402943780947059 GO:0017154 semaphorin receptor activity 1/260 13/18639 0.0769230769230769 5.51449704142012 0.166962061446576 0.402943780947059 GO:0051011 microtubule minus-end binding 1/260 13/18639 0.0769230769230769 5.51449704142012 0.166962061446576 0.402943780947059 GO:0089720 caspase binding 1/260 13/18639 0.0769230769230769 5.51449704142012 0.166962061446576 0.402943780947059 GO:0140666 annealing activity 1/260 13/18639 0.0769230769230769 5.51449704142012 0.166962061446576 0.402943780947059 GO:0140852 histone ubiquitin ligase activity 1/260 13/18639 0.0769230769230769 5.51449704142012 0.166962061446576 0.402943780947059 GO:0003779 actin binding 9/260 443/18639 0.0203160270880361 1.45642472651502 0.168012725173166 0.402943780947059 GO:0004518 nuclease activity 5/260 209/18639 0.0239234449760766 1.71503496503497 0.168460835909349 0.402943780947059 GO:0051015 actin filament binding 5/260 209/18639 0.0239234449760766 1.71503496503497 0.168460835909349 0.402943780947059 GO:0004864 protein phosphatase inhibitor activity 2/260 53/18639 0.0377358490566038 2.70522496371553 0.168782742681467 0.402943780947059 GO:0004386 helicase activity 4/260 155/18639 0.0258064516129032 1.85002481389578 0.171411606860569 0.407608702928281 GO:0005161 platelet-derived growth factor receptor binding 1/260 14/18639 0.0714285714285714 5.1206043956044 0.178590423092871 0.413289714743654 GO:0034236 protein kinase A catalytic subunit binding 1/260 14/18639 0.0714285714285714 5.1206043956044 0.178590423092871 0.413289714743654 GO:0042043 neurexin family protein binding 1/260 14/18639 0.0714285714285714 5.1206043956044 0.178590423092871 0.413289714743654 GO:0043176 amine binding 1/260 14/18639 0.0714285714285714 5.1206043956044 0.178590423092871 0.413289714743654 GO:0044548 S100 protein binding 1/260 14/18639 0.0714285714285714 5.1206043956044 0.178590423092871 0.413289714743654 GO:0071933 Arp2/3 complex binding 1/260 14/18639 0.0714285714285714 5.1206043956044 0.178590423092871 0.413289714743654 GO:1990825 sequence-specific mRNA binding 1/260 14/18639 0.0714285714285714 5.1206043956044 0.178590423092871 0.413289714743654 GO:0019212 phosphatase inhibitor activity 2/260 56/18639 0.0357142857142857 2.5603021978022 0.18376575216519 0.420492587858641 GO:0004467 long-chain fatty acid-CoA ligase activity 1/260 15/18639 0.0666666666666667 4.77923076923077 0.190057080273856 0.420492587858641 GO:0005041 low-density lipoprotein particle receptor activity 1/260 15/18639 0.0666666666666667 4.77923076923077 0.190057080273856 0.420492587858641 GO:0015250 water channel activity 1/260 15/18639 0.0666666666666667 4.77923076923077 0.190057080273856 0.420492587858641 GO:0016846 carbon-sulfur lyase activity 1/260 15/18639 0.0666666666666667 4.77923076923077 0.190057080273856 0.420492587858641 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/260 15/18639 0.0666666666666667 4.77923076923077 0.190057080273856 0.420492587858641 GO:0031386 protein tag activity 1/260 15/18639 0.0666666666666667 4.77923076923077 0.190057080273856 0.420492587858641 GO:0048531 beta-1,3-galactosyltransferase activity 1/260 15/18639 0.0666666666666667 4.77923076923077 0.190057080273856 0.420492587858641 GO:0050780 dopamine receptor binding 1/260 15/18639 0.0666666666666667 4.77923076923077 0.190057080273856 0.420492587858641 GO:0061578 K63-linked deubiquitinase activity 1/260 15/18639 0.0666666666666667 4.77923076923077 0.190057080273856 0.420492587858641 GO:0120283 protein serine/threonine kinase binding 1/260 15/18639 0.0666666666666667 4.77923076923077 0.190057080273856 0.420492587858641 GO:0141047 molecular tag activity 1/260 15/18639 0.0666666666666667 4.77923076923077 0.190057080273856 0.420492587858641 GO:0004708 MAP kinase kinase activity 1/260 16/18639 0.0625 4.48052884615385 0.201364273096494 0.435928390502803 GO:0008296 3'-5'-DNA exonuclease activity 1/260 16/18639 0.0625 4.48052884615385 0.201364273096494 0.435928390502803 GO:0034450 ubiquitin-ubiquitin ligase activity 1/260 16/18639 0.0625 4.48052884615385 0.201364273096494 0.435928390502803 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/260 16/18639 0.0625 4.48052884615385 0.201364273096494 0.435928390502803 GO:0055102 lipase inhibitor activity 1/260 16/18639 0.0625 4.48052884615385 0.201364273096494 0.435928390502803 GO:0097027 ubiquitin-protein transferase activator activity 1/260 16/18639 0.0625 4.48052884615385 0.201364273096494 0.435928390502803 GO:0031267 small GTPase binding 6/260 283/18639 0.0212014134275618 1.51989671106279 0.204324617716983 0.440757389646635 GO:0061134 peptidase regulator activity 5/260 226/18639 0.0221238938053097 1.58602791014295 0.208997975542227 0.442615804466859 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/260 17/18639 0.0588235294117647 4.21696832579186 0.212514210753955 0.442615804466859 GO:0004550 nucleoside diphosphate kinase activity 1/260 17/18639 0.0588235294117647 4.21696832579186 0.212514210753955 0.442615804466859 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/260 17/18639 0.0588235294117647 4.21696832579186 0.212514210753955 0.442615804466859 GO:0008429 phosphatidylethanolamine binding 1/260 17/18639 0.0588235294117647 4.21696832579186 0.212514210753955 0.442615804466859 GO:0017110 nucleoside diphosphate phosphatase activity 1/260 17/18639 0.0588235294117647 4.21696832579186 0.212514210753955 0.442615804466859 GO:0032183 SUMO binding 1/260 17/18639 0.0588235294117647 4.21696832579186 0.212514210753955 0.442615804466859 GO:0045236 CXCR chemokine receptor binding 1/260 17/18639 0.0588235294117647 4.21696832579186 0.212514210753955 0.442615804466859 GO:0070403 NAD+ binding 1/260 17/18639 0.0588235294117647 4.21696832579186 0.212514210753955 0.442615804466859 GO:0070492 oligosaccharide binding 1/260 17/18639 0.0588235294117647 4.21696832579186 0.212514210753955 0.442615804466859 GO:0140030 modification-dependent protein binding 4/260 173/18639 0.023121387283237 1.65753668297021 0.222580345705696 0.454543701879341 GO:0005372 water transmembrane transporter activity 1/260 18/18639 0.0555555555555556 3.98269230769231 0.223509071950603 0.454543701879341 GO:0016854 racemase and epimerase activity 1/260 18/18639 0.0555555555555556 3.98269230769231 0.223509071950603 0.454543701879341 GO:0030228 lipoprotein particle receptor activity 1/260 18/18639 0.0555555555555556 3.98269230769231 0.223509071950603 0.454543701879341 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/260 18/18639 0.0555555555555556 3.98269230769231 0.223509071950603 0.454543701879341 GO:0098641 cadherin binding involved in cell-cell adhesion 1/260 18/18639 0.0555555555555556 3.98269230769231 0.223509071950603 0.454543701879341 GO:1990381 ubiquitin-specific protease binding 1/260 18/18639 0.0555555555555556 3.98269230769231 0.223509071950603 0.454543701879341 GO:0030506 ankyrin binding 1/260 19/18639 0.0526315789473684 3.77307692307692 0.234351005321144 0.457537835604128 GO:0042834 peptidoglycan binding 1/260 19/18639 0.0526315789473684 3.77307692307692 0.234351005321144 0.457537835604128 GO:0043395 heparan sulfate proteoglycan binding 1/260 19/18639 0.0526315789473684 3.77307692307692 0.234351005321144 0.457537835604128 GO:0046527 glucosyltransferase activity 1/260 19/18639 0.0526315789473684 3.77307692307692 0.234351005321144 0.457537835604128 GO:0050145 nucleoside monophosphate kinase activity 1/260 19/18639 0.0526315789473684 3.77307692307692 0.234351005321144 0.457537835604128 GO:0097001 ceramide binding 1/260 19/18639 0.0526315789473684 3.77307692307692 0.234351005321144 0.457537835604128 GO:0140036 ubiquitin-modified protein reader activity 1/260 19/18639 0.0526315789473684 3.77307692307692 0.234351005321144 0.457537835604128 GO:1990380 K48-linked deubiquitinase activity 1/260 19/18639 0.0526315789473684 3.77307692307692 0.234351005321144 0.457537835604128 GO:0001664 G protein-coupled receptor binding 6/260 297/18639 0.0202020202020202 1.44825174825175 0.235467091428542 0.457537835604128 GO:0030695 GTPase regulator activity 9/260 489/18639 0.0184049079754601 1.3194195375177 0.244816834370539 0.457537835604128 GO:0000339 RNA cap binding 1/260 20/18639 0.05 3.58442307692308 0.24504212984405 0.457537835604128 GO:0043024 ribosomal small subunit binding 1/260 20/18639 0.05 3.58442307692308 0.24504212984405 0.457537835604128 GO:0052745 inositol phosphate phosphatase activity 1/260 20/18639 0.05 3.58442307692308 0.24504212984405 0.457537835604128 GO:0005548 phospholipid transporter activity 2/260 68/18639 0.0294117647058824 2.10848416289593 0.245137558528242 0.457537835604128 GO:1990841 promoter-specific chromatin binding 2/260 68/18639 0.0294117647058824 2.10848416289593 0.245137558528242 0.457537835604128 GO:0060589 nucleoside-triphosphatase regulator activity 9/260 490/18639 0.0183673469387755 1.31672684458399 0.246611527503291 0.457537835604128 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/260 243/18639 0.0205761316872428 1.47507122507123 0.252329589282965 0.457537835604128 GO:0001846 opsonin binding 1/260 21/18639 0.0476190476190476 3.41373626373626 0.25558453524931 0.457537835604128 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/260 21/18639 0.0476190476190476 3.41373626373626 0.25558453524931 0.457537835604128 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/260 21/18639 0.0476190476190476 3.41373626373626 0.25558453524931 0.457537835604128 GO:0019200 carbohydrate kinase activity 1/260 21/18639 0.0476190476190476 3.41373626373626 0.25558453524931 0.457537835604128 GO:0035613 RNA stem-loop binding 1/260 21/18639 0.0476190476190476 3.41373626373626 0.25558453524931 0.457537835604128 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/260 21/18639 0.0476190476190476 3.41373626373626 0.25558453524931 0.457537835604128 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0004711 ribosomal protein S6 kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0035175 histone H3S10 kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0035979 histone H2AXS139 kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0044022 histone H3S28 kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0044023 histone H4S1 kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0044024 histone H2AS1 kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0044025 histone H2BS14 kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0072354 histone H3T3 kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0072371 histone H2AS121 kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0140823 histone H2BS36 kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0140855 histone H3S57 kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0140995 histone H2A kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0140997 histone H4 kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0140998 histone H2B kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:1990244 histone H2AT120 kinase activity 5/260 245/18639 0.0204081632653061 1.46302982731554 0.257574151850395 0.457537835604128 GO:0004677 DNA-dependent protein kinase activity 5/260 246/18639 0.0203252032520325 1.45708255159475 0.260206377730164 0.457537835604128 GO:0140857 histone H3T45 kinase activity 5/260 246/18639 0.0203252032520325 1.45708255159475 0.260206377730164 0.457537835604128 GO:0042826 histone deacetylase binding 3/260 127/18639 0.0236220472440945 1.69342822531799 0.261115594974978 0.457537835604128 GO:0035402 histone H3T11 kinase activity 5/260 247/18639 0.0202429149797571 1.45118343195266 0.262845015183369 0.457537835604128 GO:0035403 histone H3T6 kinase activity 5/260 247/18639 0.0202429149797571 1.45118343195266 0.262845015183369 0.457537835604128 GO:0008234 cysteine-type peptidase activity 4/260 187/18639 0.0213903743315508 1.53344302756067 0.264794665410488 0.457537835604128 GO:0031406 carboxylic acid binding 4/260 187/18639 0.0213903743315508 1.53344302756067 0.264794665410488 0.457537835604128 GO:0004679 AMP-activated protein kinase activity 5/260 248/18639 0.0201612903225806 1.44533188585608 0.26548990081304 0.457537835604128 GO:0008093 cytoskeletal anchor activity 1/260 22/18639 0.0454545454545455 3.25856643356643 0.265980282420606 0.457537835604128 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/260 22/18639 0.0454545454545455 3.25856643356643 0.265980282420606 0.457537835604128 GO:0033691 sialic acid binding 1/260 22/18639 0.0454545454545455 3.25856643356643 0.265980282420606 0.457537835604128 GO:0070034 telomerase RNA binding 1/260 22/18639 0.0454545454545455 3.25856643356643 0.265980282420606 0.457537835604128 GO:0140035 ubiquitin-like protein reader activity 1/260 22/18639 0.0454545454545455 3.25856643356643 0.265980282420606 0.457537835604128 GO:0042277 peptide binding 5/260 249/18639 0.0200803212851406 1.43952734012975 0.268140871430657 0.457537835604128 GO:0043177 organic acid binding 4/260 189/18639 0.0211640211640212 1.51721611721612 0.270950040083297 0.457537835604128 GO:0043539 protein serine/threonine kinase activator activity 2/260 73/18639 0.0273972602739726 1.96406743940991 0.271015288621845 0.457537835604128 GO:0048029 monosaccharide binding 2/260 74/18639 0.027027027027027 1.93752598752599 0.276191817051303 0.457537835604128 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/260 23/18639 0.0434782608695652 3.11688963210702 0.276231403791967 0.457537835604128 GO:0004602 glutathione peroxidase activity 1/260 23/18639 0.0434782608695652 3.11688963210702 0.276231403791967 0.457537835604128 GO:0005158 insulin receptor binding 1/260 23/18639 0.0434782608695652 3.11688963210702 0.276231403791967 0.457537835604128 GO:0042171 lysophosphatidic acid acyltransferase activity 1/260 23/18639 0.0434782608695652 3.11688963210702 0.276231403791967 0.457537835604128 GO:0043274 phospholipase binding 1/260 23/18639 0.0434782608695652 3.11688963210702 0.276231403791967 0.457537835604128 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/260 23/18639 0.0434782608695652 3.11688963210702 0.276231403791967 0.457537835604128 GO:0071617 lysophospholipid acyltransferase activity 1/260 23/18639 0.0434782608695652 3.11688963210702 0.276231403791967 0.457537835604128 GO:0099186 structural constituent of postsynapse 1/260 23/18639 0.0434782608695652 3.11688963210702 0.276231403791967 0.457537835604128 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/260 23/18639 0.0434782608695652 3.11688963210702 0.276231403791967 0.457537835604128 GO:0019003 GDP binding 2/260 75/18639 0.0266666666666667 1.91169230769231 0.281366332538097 0.457537835604128 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0005540 hyaluronic acid binding 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0015149 hexose transmembrane transporter activity 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0030552 cAMP binding 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0048027 mRNA 5'-UTR binding 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0050431 transforming growth factor beta binding 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0050699 WW domain binding 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0055056 D-glucose transmembrane transporter activity 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0060229 lipase activator activity 1/260 24/18639 0.0416666666666667 2.98701923076923 0.286339903739007 0.457537835604128 GO:0044325 transmembrane transporter binding 3/260 136/18639 0.0220588235294118 1.58136312217195 0.295177923973965 0.458082572584412 GO:0001848 complement binding 1/260 25/18639 0.04 2.86753846153846 0.296307758964785 0.458082572584412 GO:0005537 D-mannose binding 1/260 25/18639 0.04 2.86753846153846 0.296307758964785 0.458082572584412 GO:0008139 nuclear localization sequence binding 1/260 25/18639 0.04 2.86753846153846 0.296307758964785 0.458082572584412 GO:0015645 fatty acid ligase activity 1/260 25/18639 0.04 2.86753846153846 0.296307758964785 0.458082572584412 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/260 25/18639 0.04 2.86753846153846 0.296307758964785 0.458082572584412 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/260 25/18639 0.04 2.86753846153846 0.296307758964785 0.458082572584412 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/260 25/18639 0.04 2.86753846153846 0.296307758964785 0.458082572584412 GO:0019707 protein-cysteine S-acyltransferase activity 1/260 25/18639 0.04 2.86753846153846 0.296307758964785 0.458082572584412 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/260 25/18639 0.04 2.86753846153846 0.296307758964785 0.458082572584412 GO:0120515 fatty acid-CoA ligase activity 1/260 25/18639 0.04 2.86753846153846 0.296307758964785 0.458082572584412 GO:0140098 catalytic activity, acting on RNA 7/260 387/18639 0.0180878552971576 1.29669051878354 0.296389723408452 0.458082572584412 GO:0016922 nuclear receptor binding 3/260 137/18639 0.0218978102189781 1.56982032565974 0.298984103794659 0.458082572584412 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/260 26/18639 0.0384615384615385 2.75724852071006 0.306136918880395 0.458082572584412 GO:0004529 DNA exonuclease activity 1/260 26/18639 0.0384615384615385 2.75724852071006 0.306136918880395 0.458082572584412 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/260 26/18639 0.0384615384615385 2.75724852071006 0.306136918880395 0.458082572584412 GO:0008143 poly(A) binding 1/260 26/18639 0.0384615384615385 2.75724852071006 0.306136918880395 0.458082572584412 GO:0008198 ferrous iron binding 1/260 26/18639 0.0384615384615385 2.75724852071006 0.306136918880395 0.458082572584412 GO:0015145 monosaccharide transmembrane transporter activity 1/260 26/18639 0.0384615384615385 2.75724852071006 0.306136918880395 0.458082572584412 GO:0030507 spectrin binding 1/260 26/18639 0.0384615384615385 2.75724852071006 0.306136918880395 0.458082572584412 GO:0034237 protein kinase A regulatory subunit binding 1/260 26/18639 0.0384615384615385 2.75724852071006 0.306136918880395 0.458082572584412 GO:0070412 R-SMAD binding 1/260 26/18639 0.0384615384615385 2.75724852071006 0.306136918880395 0.458082572584412 GO:0097602 cullin family protein binding 1/260 26/18639 0.0384615384615385 2.75724852071006 0.306136918880395 0.458082572584412 GO:0140767 enzyme-substrate adaptor activity 3/260 139/18639 0.0215827338129496 1.54723298284449 0.306604259179733 0.458082572584412 GO:0033192 calmodulin-dependent protein phosphatase activity 2/260 81/18639 0.0246913580246914 1.77008547008547 0.312319914659372 0.458082572584412 GO:0140791 histone H2AXS140 phosphatase activity 2/260 81/18639 0.0246913580246914 1.77008547008547 0.312319914659372 0.458082572584412 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/260 81/18639 0.0246913580246914 1.77008547008547 0.312319914659372 0.458082572584412 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/260 81/18639 0.0246913580246914 1.77008547008547 0.312319914659372 0.458082572584412 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/260 81/18639 0.0246913580246914 1.77008547008547 0.312319914659372 0.458082572584412 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/260 81/18639 0.0246913580246914 1.77008547008547 0.312319914659372 0.458082572584412 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/260 81/18639 0.0246913580246914 1.77008547008547 0.312319914659372 0.458082572584412 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/260 81/18639 0.0246913580246914 1.77008547008547 0.312319914659372 0.458082572584412 GO:0004364 glutathione transferase activity 1/260 27/18639 0.037037037037037 2.65512820512821 0.31582930598033 0.458082572584412 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/260 27/18639 0.037037037037037 2.65512820512821 0.31582930598033 0.458082572584412 GO:0008320 protein transmembrane transporter activity 1/260 27/18639 0.037037037037037 2.65512820512821 0.31582930598033 0.458082572584412 GO:0016405 CoA-ligase activity 1/260 27/18639 0.037037037037037 2.65512820512821 0.31582930598033 0.458082572584412 GO:0023026 MHC class II protein complex binding 1/260 27/18639 0.037037037037037 2.65512820512821 0.31582930598033 0.458082572584412 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/260 27/18639 0.037037037037037 2.65512820512821 0.31582930598033 0.458082572584412 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/260 82/18639 0.024390243902439 1.7484990619137 0.317455256432252 0.458082572584412 GO:0033549 MAP kinase phosphatase activity 2/260 82/18639 0.024390243902439 1.7484990619137 0.317455256432252 0.458082572584412 GO:0003714 transcription corepressor activity 4/260 204/18639 0.0196078431372549 1.40565610859728 0.317775824359054 0.458082572584412 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/260 83/18639 0.0240963855421687 1.7274328081557 0.32258171882098 0.462432087041126 GO:0005242 inward rectifier potassium channel activity 1/260 28/18639 0.0357142857142857 2.5603021978022 0.325386816212713 0.462432087041126 GO:0019789 SUMO transferase activity 1/260 28/18639 0.0357142857142857 2.5603021978022 0.325386816212713 0.462432087041126 GO:0046966 nuclear thyroid hormone receptor binding 1/260 28/18639 0.0357142857142857 2.5603021978022 0.325386816212713 0.462432087041126 GO:0051019 mitogen-activated protein kinase binding 1/260 28/18639 0.0357142857142857 2.5603021978022 0.325386816212713 0.462432087041126 GO:0051119 sugar transmembrane transporter activity 1/260 28/18639 0.0357142857142857 2.5603021978022 0.325386816212713 0.462432087041126 GO:0017018 myosin phosphatase activity 2/260 84/18639 0.0238095238095238 1.70686813186813 0.327698552196473 0.464624238325515 GO:0004181 metallocarboxypeptidase activity 1/260 29/18639 0.0344827586206897 2.47201591511936 0.334811319344446 0.469201941726324 GO:0016417 S-acyltransferase activity 1/260 29/18639 0.0344827586206897 2.47201591511936 0.334811319344446 0.469201941726324 GO:0035250 UDP-galactosyltransferase activity 1/260 29/18639 0.0344827586206897 2.47201591511936 0.334811319344446 0.469201941726324 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/260 29/18639 0.0344827586206897 2.47201591511936 0.334811319344446 0.469201941726324 GO:0106222 lncRNA binding 1/260 29/18639 0.0344827586206897 2.47201591511936 0.334811319344446 0.469201941726324 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/260 86/18639 0.0232558139534884 1.66717352415027 0.337900445293321 0.472434881845291 GO:0001968 fibronectin binding 1/260 30/18639 0.0333333333333333 2.38961538461538 0.344104659321365 0.4777912970807 GO:0051721 protein phosphatase 2A binding 1/260 30/18639 0.0333333333333333 2.38961538461538 0.344104659321365 0.4777912970807 GO:0098918 structural constituent of synapse 1/260 30/18639 0.0333333333333333 2.38961538461538 0.344104659321365 0.4777912970807 GO:0016411 acylglycerol O-acyltransferase activity 1/260 31/18639 0.032258064516129 2.31253101736973 0.353268654623447 0.488270634765588 GO:0016878 acid-thiol ligase activity 1/260 31/18639 0.032258064516129 2.31253101736973 0.353268654623447 0.488270634765588 GO:0008378 galactosyltransferase activity 1/260 32/18639 0.03125 2.24026442307692 0.362305098615165 0.496218321005805 GO:0022884 macromolecule transmembrane transporter activity 1/260 32/18639 0.03125 2.24026442307692 0.362305098615165 0.496218321005805 GO:0031369 translation initiation factor binding 1/260 32/18639 0.03125 2.24026442307692 0.362305098615165 0.496218321005805 GO:0051059 NF-kappaB binding 1/260 32/18639 0.03125 2.24026442307692 0.362305098615165 0.496218321005805 GO:0140416 transcription regulator inhibitor activity 1/260 33/18639 0.0303030303030303 2.17237762237762 0.371215759891033 0.507272214873719 GO:0019825 oxygen binding 1/260 34/18639 0.0294117647058824 2.10848416289593 0.380002382616408 0.515778514832158 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/260 34/18639 0.0294117647058824 2.10848416289593 0.380002382616408 0.515778514832158 GO:0090482 vitamin transmembrane transporter activity 1/260 34/18639 0.0294117647058824 2.10848416289593 0.380002382616408 0.515778514832158 GO:0004867 serine-type endopeptidase inhibitor activity 2/260 95/18639 0.0210526315789474 1.50923076923077 0.383155379961505 0.518892039230378 GO:0003712 transcription coregulator activity 8/260 495/18639 0.0161616161616162 1.1586013986014 0.38678280027103 0.522632687614546 GO:0140566 histone reader activity 1/260 35/18639 0.0285714285714286 2.04824175824176 0.388666686863639 0.524005979610799 GO:0106310 protein serine kinase activity 6/260 361/18639 0.0166204986149584 1.1914979757085 0.390372930207389 0.525134186737779 GO:0004190 aspartic-type endopeptidase activity 1/260 36/18639 0.0277777777777778 1.99134615384615 0.397210368943592 0.530785537260906 GO:0005484 SNAP receptor activity 1/260 36/18639 0.0277777777777778 1.99134615384615 0.397210368943592 0.530785537260906 GO:0016409 palmitoyltransferase activity 1/260 36/18639 0.0277777777777778 1.99134615384615 0.397210368943592 0.530785537260906 GO:0004674 protein serine/threonine kinase activity 7/260 433/18639 0.0161662817551963 1.15893586782732 0.400210996746212 0.533614662328282 GO:0023023 MHC protein complex binding 1/260 37/18639 0.027027027027027 1.93752598752599 0.405635101732641 0.53728859966341 GO:0030551 cyclic nucleotide binding 1/260 37/18639 0.027027027027027 1.93752598752599 0.405635101732641 0.53728859966341 GO:0070001 aspartic-type peptidase activity 1/260 37/18639 0.027027027027027 1.93752598752599 0.405635101732641 0.53728859966341 GO:0016874 ligase activity 3/260 167/18639 0.0179640718562874 1.28781667434362 0.412761810759469 0.544708695287758 GO:0005109 frizzled binding 1/260 38/18639 0.0263157894736842 1.88653846153846 0.413942534995167 0.544708695287758 GO:0042887 amide transmembrane transporter activity 1/260 38/18639 0.0263157894736842 1.88653846153846 0.413942534995167 0.544708695287758 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/260 39/18639 0.0256410256410256 1.83816568047337 0.422134295701648 0.553222535042367 GO:0004722 protein serine/threonine phosphatase activity 2/260 103/18639 0.0194174757281553 1.39200896191187 0.422244352077038 0.553222535042367 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/260 40/18639 0.025 1.79221153846154 0.430211988342378 0.561226870321374 GO:0071949 FAD binding 1/260 40/18639 0.025 1.79221153846154 0.430211988342378 0.561226870321374 GO:0008201 heparin binding 3/260 172/18639 0.0174418604651163 1.2503801431127 0.431301831061645 0.561436004226796 GO:0008013 beta-catenin binding 2/260 106/18639 0.0188679245283019 1.35261248185776 0.436575970763045 0.56551073915188 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/260 41/18639 0.024390243902439 1.7484990619137 0.438177195236887 0.56551073915188 GO:0042169 SH2 domain binding 1/260 41/18639 0.024390243902439 1.7484990619137 0.438177195236887 0.56551073915188 GO:0140318 protein transporter activity 1/260 41/18639 0.024390243902439 1.7484990619137 0.438177195236887 0.56551073915188 GO:0004843 cysteine-type deubiquitinase activity 2/260 108/18639 0.0185185185185185 1.3275641025641 0.446023247481051 0.570769093243287 GO:0008307 structural constituent of muscle 1/260 42/18639 0.0238095238095238 1.70686813186813 0.446031476839125 0.570769093243287 GO:0031492 nucleosomal DNA binding 1/260 42/18639 0.0238095238095238 1.70686813186813 0.446031476839125 0.570769093243287 GO:0051879 Hsp90 protein binding 1/260 42/18639 0.0238095238095238 1.70686813186813 0.446031476839125 0.570769093243287 GO:0043021 ribonucleoprotein complex binding 3/260 177/18639 0.0169491525423729 1.21505867014342 0.449628350290773 0.57339106424942 GO:0004620 phospholipase activity 2/260 109/18639 0.018348623853211 1.31538461538462 0.450713768362204 0.57339106424942 GO:0033218 amide binding 4/260 247/18639 0.0161943319838057 1.16094674556213 0.452863517140121 0.57339106424942 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/260 43/18639 0.0232558139534884 1.66717352415027 0.453776372038448 0.57339106424942 GO:0008375 acetylglucosaminyltransferase activity 1/260 43/18639 0.0232558139534884 1.66717352415027 0.453776372038448 0.57339106424942 GO:0048156 tau protein binding 1/260 43/18639 0.0232558139534884 1.66717352415027 0.453776372038448 0.57339106424942 GO:1902936 phosphatidylinositol bisphosphate binding 2/260 111/18639 0.018018018018018 1.29168399168399 0.460027077925872 0.580075897843897 GO:0019205 nucleobase-containing compound kinase activity 1/260 44/18639 0.0227272727272727 1.62928321678322 0.461413398456496 0.580611859724424 GO:0043022 ribosome binding 2/260 112/18639 0.0178571428571429 1.2801510989011 0.464649305306186 0.583468150530014 GO:0042605 peptide antigen binding 1/260 45/18639 0.0222222222222222 1.59307692307692 0.468944052739976 0.585211173254019 GO:0046915 transition metal ion transmembrane transporter activity 1/260 45/18639 0.0222222222222222 1.59307692307692 0.468944052739976 0.585211173254019 GO:0051539 4 iron, 4 sulfur cluster binding 1/260 45/18639 0.0222222222222222 1.59307692307692 0.468944052739976 0.585211173254019 GO:0004180 carboxypeptidase activity 1/260 46/18639 0.0217391304347826 1.55844481605351 0.476369810849452 0.592031616775862 GO:0030291 protein serine/threonine kinase inhibitor activity 1/260 46/18639 0.0217391304347826 1.55844481605351 0.476369810849452 0.592031616775862 GO:0101005 deubiquitinase activity 2/260 115/18639 0.0173913043478261 1.24675585284281 0.478375162351634 0.593303076099357 GO:0003713 transcription coactivator activity 4/260 256/18639 0.015625 1.12013221153846 0.480293037115491 0.594461054134747 GO:0009055 electron transfer activity 2/260 116/18639 0.0172413793103448 1.23600795755968 0.482902708419996 0.59622458269362 GO:0043495 protein-membrane adaptor activity 1/260 47/18639 0.0212765957446809 1.52528641571195 0.483692128344162 0.59622458269362 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/260 48/18639 0.0208333333333333 1.49350961538462 0.490912440662929 0.603892289532402 GO:0048020 CCR chemokine receptor binding 1/260 50/18639 0.02 1.43376923076923 0.505052692584423 0.620024037237788 GO:0005048 signal sequence binding 1/260 51/18639 0.0196078431372549 1.40565610859728 0.511975404937323 0.62724775777311 GO:0016757 glycosyltransferase activity 4/260 267/18639 0.0149812734082397 1.07398444252377 0.513068047025843 0.627313968428358 GO:0030159 signaling receptor complex adaptor activity 1/260 52/18639 0.0192307692307692 1.37862426035503 0.518801658149949 0.633042831358726 GO:0005096 GTPase activator activity 4/260 271/18639 0.014760147601476 1.05813227363043 0.524753227455894 0.634843611696791 GO:0005246 calcium channel regulator activity 1/260 53/18639 0.0188679245283019 1.35261248185776 0.525532791139728 0.634843611696791 GO:0005544 calcium-dependent phospholipid binding 1/260 53/18639 0.0188679245283019 1.35261248185776 0.525532791139728 0.634843611696791 GO:0016860 intramolecular oxidoreductase activity 1/260 53/18639 0.0188679245283019 1.35261248185776 0.525532791139728 0.634843611696791 GO:0051018 protein kinase A binding 1/260 53/18639 0.0188679245283019 1.35261248185776 0.525532791139728 0.634843611696791 GO:0019783 ubiquitin-like protein peptidase activity 2/260 127/18639 0.015748031496063 1.12895215021199 0.531065347637295 0.636496544719351 GO:0003925 G protein activity 1/260 54/18639 0.0185185185185185 1.3275641025641 0.532170124310053 0.636496544719351 GO:0017069 snRNA binding 1/260 54/18639 0.0185185185185185 1.3275641025641 0.532170124310053 0.636496544719351 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/260 54/18639 0.0185185185185185 1.3275641025641 0.532170124310053 0.636496544719351 GO:0051287 NAD binding 1/260 54/18639 0.0185185185185185 1.3275641025641 0.532170124310053 0.636496544719351 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/260 128/18639 0.015625 1.12013221153846 0.535290545865727 0.638909897907397 GO:1901681 sulfur compound binding 4/260 275/18639 0.0145454545454545 1.04274125874126 0.536303507018295 0.638909897907397 GO:0008374 O-acyltransferase activity 1/260 55/18639 0.0181818181818182 1.30342657342657 0.538714959805312 0.640519361658285 GO:0005543 phospholipid binding 7/260 497/18639 0.0140845070422535 1.00969664138678 0.543094557847039 0.643867072207216 GO:0016298 lipase activity 2/260 130/18639 0.0153846153846154 1.10289940828402 0.543662594082252 0.643867072207216 GO:0005262 calcium channel activity 2/260 131/18639 0.0152671755725191 1.09448032883147 0.5478092580635 0.647508398963511 GO:0004601 peroxidase activity 1/260 57/18639 0.0175438596491228 1.25769230769231 0.55153225655882 0.650635708909233 GO:0005516 calmodulin binding 3/260 207/18639 0.0144927536231884 1.03896321070234 0.553727601775365 0.651952186105888 GO:0001786 phosphatidylserine binding 1/260 59/18639 0.0169491525423729 1.21505867014342 0.563994742847142 0.657630935675046 GO:0004879 nuclear receptor activity 1/260 59/18639 0.0169491525423729 1.21505867014342 0.563994742847142 0.657630935675046 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/260 59/18639 0.0169491525423729 1.21505867014342 0.563994742847142 0.657630935675046 GO:0031593 polyubiquitin modification-dependent protein binding 1/260 59/18639 0.0169491525423729 1.21505867014342 0.563994742847142 0.657630935675046 GO:0070888 E-box binding 1/260 59/18639 0.0169491525423729 1.21505867014342 0.563994742847142 0.657630935675046 GO:0016779 nucleotidyltransferase activity 2/260 136/18639 0.0147058823529412 1.05424208144796 0.568145928711524 0.661194876573719 GO:0098531 ligand-modulated transcription factor activity 1/260 60/18639 0.0166666666666667 1.19480769230769 0.57009600048222 0.662188431329348 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/260 61/18639 0.0163934426229508 1.17522068095839 0.576112203715689 0.667892074941029 GO:0030295 protein kinase activator activity 2/260 139/18639 0.0143884892086331 1.03148865522966 0.580028563549967 0.671144161655517 GO:0005507 copper ion binding 1/260 63/18639 0.0158730158730159 1.13791208791209 0.587894155372777 0.678944684216361 GO:0004536 DNA nuclease activity 1/260 64/18639 0.015625 1.12013221153846 0.593662217366913 0.684297670400029 GO:0038024 cargo receptor activity 1/260 65/18639 0.0153846153846154 1.10289940828402 0.59934985254778 0.689537735121636 GO:0008194 UDP-glycosyltransferase activity 2/260 145/18639 0.0137931034482759 0.988806366047745 0.603071122977765 0.692499920681692 GO:0008235 metalloexopeptidase activity 1/260 66/18639 0.0151515151515152 1.08618881118881 0.60495817807473 0.693348651911076 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/260 67/18639 0.0149253731343284 1.06997703788749 0.610488295648658 0.697097711940218 GO:0015085 calcium ion transmembrane transporter activity 2/260 147/18639 0.0136054421768707 0.975353218210361 0.610537565590026 0.697097711940218 GO:0019209 kinase activator activity 2/260 148/18639 0.0135135135135135 0.968762993762994 0.614230614932379 0.699991115885202 GO:0002039 p53 binding 1/260 69/18639 0.0144927536231884 1.03896321070234 0.621318237724301 0.705096772623302 GO:0008080 N-acetyltransferase activity 1/260 69/18639 0.0144927536231884 1.03896321070234 0.621318237724301 0.705096772623302 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/260 229/18639 0.0131004366812227 0.939150151158885 0.622212880477185 0.705096772623302 GO:0000287 magnesium ion binding 3/260 230/18639 0.0130434782608696 0.935066889632107 0.625150601042276 0.705777500989785 GO:0005085 guanyl-nucleotide exchange factor activity 3/260 230/18639 0.0130434782608696 0.935066889632107 0.625150601042276 0.705777500989785 GO:0005518 collagen binding 1/260 72/18639 0.0138888888888889 0.995673076923077 0.6370032682662 0.717817115732807 GO:0003678 DNA helicase activity 1/260 74/18639 0.0135135135135135 0.968762993762994 0.64709868968575 0.726482543810767 GO:0031491 nucleosome binding 1/260 74/18639 0.0135135135135135 0.968762993762994 0.64709868968575 0.726482543810767 GO:0051536 iron-sulfur cluster binding 1/260 76/18639 0.0131578947368421 0.943269230769231 0.656914393922719 0.73477091468393 GO:0140034 methylation-dependent protein binding 1/260 76/18639 0.0131578947368421 0.943269230769231 0.656914393922719 0.73477091468393 GO:0051540 metal cluster binding 1/260 77/18639 0.012987012987013 0.931018981018981 0.661719773310754 0.738777713640841 GO:0042393 histone binding 3/260 247/18639 0.0121457489878543 0.870710059171598 0.672687179287703 0.749636635220983 GO:0000049 tRNA binding 1/260 80/18639 0.0125 0.896105769230769 0.675737323005241 0.751648882311539 GO:0030971 receptor tyrosine kinase binding 1/260 81/18639 0.0123456790123457 0.885042735042735 0.680280040609565 0.755310927441502 GO:0008135 translation factor activity, RNA binding 1/260 83/18639 0.0120481927710843 0.86371640407785 0.689176159421909 0.763784220717125 GO:0051117 ATPase binding 1/260 84/18639 0.0119047619047619 0.853434065934066 0.693531311316192 0.765800570447861 GO:0180051 translation factor activity 1/260 84/18639 0.0119047619047619 0.853434065934066 0.693531311316192 0.765800570447861 GO:0003823 antigen binding 2/260 174/18639 0.0114942528735632 0.824005305039788 0.701000639872103 0.772393974666408 GO:0050660 flavin adenine dinucleotide binding 1/260 86/18639 0.0116279069767442 0.833586762075134 0.702060086244798 0.772393974666408 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/260 88/18639 0.0113636363636364 0.814641608391608 0.710352399814049 0.78009608997761 GO:0005319 lipid transporter activity 2/260 178/18639 0.0112359550561798 0.805488331892826 0.712813904517522 0.781378581358591 GO:0016853 isomerase activity 2/260 180/18639 0.0111111111111111 0.796538461538462 0.718573034962259 0.786264697676095 GO:0072341 modified amino acid binding 1/260 91/18639 0.010989010989011 0.787785291631446 0.722361743079128 0.788980999674129 GO:0051213 dioxygenase activity 1/260 93/18639 0.010752688172043 0.770843672456576 0.73009108593636 0.795983783223035 GO:1901981 phosphatidylinositol phosphate binding 2/260 185/18639 0.0108108108108108 0.775010395010395 0.732547989037907 0.797223397079091 GO:0016410 N-acyltransferase activity 1/260 94/18639 0.0106382978723404 0.762643207855974 0.733874991773551 0.797231106171268 GO:0008276 protein methyltransferase activity 1/260 95/18639 0.0105263157894737 0.754615384615385 0.73760605147368 0.799845700341297 GO:0016407 acetyltransferase activity 1/260 96/18639 0.0104166666666667 0.746754807692308 0.741285000277435 0.802394516429338 GO:0005249 voltage-gated potassium channel activity 1/260 98/18639 0.0102040816326531 0.731514913657771 0.748489455348287 0.805860304866961 GO:0008170 N-methyltransferase activity 1/260 98/18639 0.0102040816326531 0.731514913657771 0.748489455348287 0.805860304866961 GO:0042626 ATPase-coupled transmembrane transporter activity 1/260 98/18639 0.0102040816326531 0.731514913657771 0.748489455348287 0.805860304866961 GO:0035091 phosphatidylinositol binding 3/260 284/18639 0.0105633802816901 0.757272481040087 0.760507997744359 0.81734311501351 GO:0008238 exopeptidase activity 1/260 102/18639 0.00980392156862745 0.702828054298642 0.762304271355218 0.817818436764745 GO:0016758 hexosyltransferase activity 2/260 197/18639 0.0101522842639594 0.727801639984381 0.763702165852561 0.817865440026501 GO:0016829 lyase activity 2/260 200/18639 0.01 0.716884615384615 0.770983687278845 0.824202030294553 GO:0000149 SNARE binding 1/260 106/18639 0.00943396226415094 0.676306240928882 0.77536303376803 0.827419209180018 GO:0022853 active monoatomic ion transmembrane transporter activity 1/260 118/18639 0.00847457627118644 0.607529335071708 0.810404182907023 0.863287701015594 GO:0004175 endopeptidase activity 4/260 405/18639 0.00987654320987654 0.708034188034188 0.819689948060404 0.869790935512534 GO:0008528 G protein-coupled peptide receptor activity 1/260 122/18639 0.00819672131147541 0.587610340479193 0.82082919410951 0.869790935512534 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/260 122/18639 0.00819672131147541 0.587610340479193 0.82082919410951 0.869790935512534 GO:0005267 potassium channel activity 1/260 124/18639 0.00806451612903226 0.578132754342432 0.8258255326574 0.87355275258331 GO:0001653 peptide receptor activity 1/260 128/18639 0.0078125 0.560066105769231 0.835405632289476 0.882141611718258 GO:0031072 heat shock protein binding 1/260 131/18639 0.00763358778625954 0.547240164415737 0.842244568819913 0.887811028913137 GO:0099094 ligand-gated monoatomic cation channel activity 1/260 136/18639 0.00735294117647059 0.527121040723982 0.853019444881222 0.897602342697314 GO:0005261 monoatomic cation channel activity 3/260 341/18639 0.00879765395894428 0.630690277464471 0.857630586072518 0.900884998239654 GO:0140101 catalytic activity, acting on a tRNA 1/260 139/18639 0.00719424460431655 0.515744327614831 0.859129126491145 0.900892347917798 GO:0020037 heme binding 1/260 142/18639 0.00704225352112676 0.504848320693391 0.864985777327037 0.905461714914264 GO:0022843 voltage-gated monoatomic cation channel activity 1/260 143/18639 0.00699300699300699 0.501317912856374 0.8668835822627 0.90587834547867 GO:0046873 metal ion transmembrane transporter activity 4/260 450/18639 0.00888888888888889 0.637230769230769 0.876709818905654 0.914564301587246 GO:0046906 tetrapyrrole binding 1/260 152/18639 0.00657894736842105 0.471634615384615 0.882811372609063 0.919341498372197 GO:0005506 iron ion binding 1/260 154/18639 0.00649350649350649 0.465509490509491 0.886084548169617 0.92116190549819 GO:0015079 potassium ion transmembrane transporter activity 1/260 160/18639 0.00625 0.448052884615385 0.895367620744659 0.927619284613678 GO:0099106 ion channel regulator activity 1/260 160/18639 0.00625 0.448052884615385 0.895367620744659 0.927619284613678 GO:0008083 growth factor activity 1/260 162/18639 0.00617283950617284 0.442521367521367 0.898291346157086 0.92905474842274 GO:0015399 primary active transmembrane transporter activity 1/260 166/18639 0.00602409638554217 0.431858202038925 0.903896879121451 0.931252067869394 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/260 167/18639 0.00598802395209581 0.429272224781207 0.905249491660206 0.931252067869394 GO:0005201 extracellular matrix structural constituent 1/260 168/18639 0.00595238095238095 0.426717032967033 0.906583138919212 0.931252067869394 GO:0016247 channel regulator activity 1/260 168/18639 0.00595238095238095 0.426717032967033 0.906583138919212 0.931252067869394 GO:0141108 transporter regulator activity 1/260 170/18639 0.00588235294117647 0.421696832579185 0.909194593528062 0.932348954993123 GO:0005244 voltage-gated monoatomic ion channel activity 1/260 173/18639 0.00578034682080925 0.414384170742552 0.912976039716897 0.934639877947468 GO:0022832 voltage-gated channel activity 1/260 175/18639 0.00571428571428571 0.409648351648352 0.915409435780285 0.935545345535181 GO:0008237 metallopeptidase activity 1/260 184/18639 0.00543478260869565 0.389611204013378 0.925547524514587 0.943247301375766 GO:0015078 proton transmembrane transporter activity 1/260 185/18639 0.00540540540540541 0.387505197505198 0.926596435033482 0.943247301375766 GO:0015276 ligand-gated monoatomic ion channel activity 1/260 186/18639 0.00537634408602151 0.385421836228288 0.927630624200671 0.943247301375766 GO:0022834 ligand-gated channel activity 1/260 188/18639 0.00531914893617021 0.381321603927987 0.929655658917515 0.943717677287695 GO:0008236 serine-type peptidase activity 1/260 194/18639 0.00515463917525773 0.369528152260111 0.935398275897785 0.94795395745346 GO:0017171 serine hydrolase activity 1/260 198/18639 0.00505050505050505 0.362062937062937 0.938964757854459 0.949974394881228 GO:0008168 methyltransferase activity 1/260 204/18639 0.00490196078431373 0.351414027149321 0.943950026330057 0.953421096828352 GO:0005216 monoatomic ion channel activity 3/260 448/18639 0.00669642857142857 0.480056662087912 0.951290921776671 0.958406745060036 GO:0016741 transferase activity, transferring one-carbon groups 1/260 215/18639 0.00465116279069767 0.333434704830054 0.952059680523214 0.958406745060036 GO:0003730 mRNA 3'-UTR binding 1/260 262/18639 0.00381679389312977 0.273620082207868 0.975439835597591 0.980308919635515 GO:0008514 organic anion transmembrane transporter activity 1/260 269/18639 0.00371747211895911 0.266499857020303 0.977771721542022 0.981020132577045 GO:0022836 gated channel activity 1/260 318/18639 0.00314465408805031 0.225435413642961 0.988955110509703 0.990595168736088 GO:0022804 active transmembrane transporter activity 1/260 457/18639 0.00218818380743982 0.156867530718734 0.998496699950143 0.998496699950143