ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0043021	ribonucleoprotein complex binding	72/3360	177/18639	0.406779661016949	2.25653753026634	1.32138005333723e-12	1.73761477013845e-09
GO:0051082	unfolded protein binding	52/3360	121/18639	0.429752066115702	2.38397284533648	1.55659010309309e-10	1.02345799278371e-07
GO:0044389	ubiquitin-like protein ligase binding	101/3360	322/18639	0.313664596273292	1.73999833629104	3.62550226677911e-09	1.58917849360484e-06
GO:0003712	transcription coregulator activity	141/3360	495/18639	0.284848484848485	1.5801461038961	4.84886007081454e-09	1.59406274828028e-06
GO:0031625	ubiquitin protein ligase binding	94/3360	302/18639	0.311258278145695	1.72664971617786	1.90475838548148e-08	4.61147938055889e-06
GO:0140104	molecular carrier activity	81/3360	249/18639	0.325301204819277	1.80455034423408	2.10409705576832e-08	4.61147938055889e-06
GO:0140662	ATP-dependent protein folding chaperone	23/3360	40/18639	0.575	3.18970982142857	2.62951390256783e-08	4.93972968839528e-06
GO:0016887	ATP hydrolysis activity	120/3360	417/18639	0.287769784172662	1.59635149023638	3.62050511844781e-08	5.61956375446341e-06
GO:0140098	catalytic activity, acting on RNA	113/3360	387/18639	0.291989664082687	1.61976052048726	3.84608926160994e-08	5.61956375446341e-06
GO:0044183	protein folding chaperone	34/3360	75/18639	0.453333333333333	2.51478571428571	4.53058494653032e-08	5.95771920468738e-06
GO:0043022	ribosome binding	44/3360	112/18639	0.392857142857143	2.17930484693878	9.86058872389222e-08	1.17878856108348e-05
GO:0019787	ubiquitin-like protein transferase activity	132/3360	479/18639	0.275574112734864	1.52869818073367	1.25417518481489e-07	1.37436697335965e-05
GO:0016755	aminoacyltransferase activity	135/3360	496/18639	0.272177419354839	1.50985563076037	1.97148948319836e-07	1.99423743877373e-05
GO:0001221	transcription coregulator binding	44/3360	115/18639	0.382608695652174	2.12245341614907	2.40752397738589e-07	2.23623172511233e-05
GO:0005525	GTP binding	108/3360	378/18639	0.285714285714286	1.58494897959184	2.55083466742852e-07	2.23623172511233e-05
GO:0001222	transcription corepressor binding	24/3360	49/18639	0.489795918367347	2.71705539358601	7.45454463208643e-07	6.12670386949604e-05
GO:0004842	ubiquitin-protein transferase activity	122/3360	449/18639	0.271714922048998	1.50729000954502	8.30398762863319e-07	6.42337866567803e-05
GO:0016741	transferase activity, transferring one-carbon groups	68/3360	215/18639	0.316279069767442	1.75450166112957	8.84114669598009e-07	6.4589488362299e-05
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	55/3360	167/18639	0.329341317365269	1.8269621471343	2.40331617362273e-06	0.000163376309611383
GO:0008168	methyltransferase activity	64/3360	204/18639	0.313725490196078	1.74033613445378	2.48481079256857e-06	0.000163376309611383
GO:0140597	protein carrier chaperone	60/3360	188/18639	0.319148936170213	1.7704217325228	2.73518024163661e-06	0.000171274381797721
GO:0019001	guanyl nucleotide binding	108/3360	400/18639	0.27	1.49777678571429	4.75097692840153e-06	0.000271631941776
GO:0032561	guanyl ribonucleotide binding	108/3360	400/18639	0.27	1.49777678571429	4.75097692840153e-06	0.000271631941776
GO:0003714	transcription corepressor activity	63/3360	204/18639	0.308823529411765	1.71314338235294	5.27954486999419e-06	0.000289275062668431
GO:0140674	ATP-dependent histone chaperone activity	50/3360	152/18639	0.328947368421053	1.82477678571429	7.02073748141942e-06	0.000365476369924688
GO:0008094	ATP-dependent activity, acting on DNA	64/3360	210/18639	0.304761904761905	1.69061224489796	7.22614875896721e-06	0.000365476369924688
GO:0140142	nucleocytoplasmic carrier activity	17/3360	32/18639	0.53125	2.94701450892857	7.6635438154003e-06	0.000373242967305607
GO:0140693	molecular condensate scaffold activity	22/3360	48/18639	0.458333333333333	2.54252232142857	8.51803165614075e-06	0.000389863463736935
GO:0008170	N-methyltransferase activity	36/3360	98/18639	0.36734693877551	2.0377915451895	8.59774939039628e-06	0.000389863463736935
GO:0140658	ATP-dependent chromatin remodeler activity	51/3360	158/18639	0.322784810126582	1.79059109403255	1.04046621312088e-05	0.000456071023417985
GO:0051087	protein-folding chaperone binding	45/3360	134/18639	0.335820895522388	1.86290644989339	1.08785245678217e-05	0.000461459993764048
GO:0000510	H3-H4 histone complex chaperone activity	49/3360	151/18639	0.324503311258278	1.80012417218543	1.30844779385021e-05	0.000491602528260863
GO:0140584	chromatin extrusion motor activity	49/3360	151/18639	0.324503311258278	1.80012417218543	1.30844779385021e-05	0.000491602528260863
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	49/3360	151/18639	0.324503311258278	1.80012417218543	1.30844779385021e-05	0.000491602528260863
GO:0140849	ATP-dependent H2AZ histone chaperone activity	49/3360	151/18639	0.324503311258278	1.80012417218543	1.30844779385021e-05	0.000491602528260863
GO:0016853	isomerase activity	56/3360	180/18639	0.311111111111111	1.72583333333333	1.34944245017539e-05	0.000492921339439067
GO:0140713	histone chaperone activity	52/3360	164/18639	0.317073170731707	1.75890679442509	1.50349910084618e-05	0.000534351707462899
GO:0015616	DNA translocase activity	49/3360	152/18639	0.322368421052632	1.78828125	1.59691700006092e-05	0.00055261733028424
GO:0016779	nucleotidyltransferase activity	45/3360	136/18639	0.330882352941176	1.83551076680672	1.66901508516758e-05	0.000562757650511633
GO:0061775	cohesin loader activity	49/3360	153/18639	0.320261437908497	1.7765931372549	1.94301619157441e-05	0.000638766572980087
GO:0140097	catalytic activity, acting on DNA	91/3360	336/18639	0.270833333333333	1.50239955357143	2.26422650530943e-05	0.000726209232800464
GO:0051536	iron-sulfur cluster binding	29/3360	76/18639	0.381578947368421	2.11674107142857	2.75445515689395e-05	0.000862406793170369
GO:0003689	DNA clamp loader activity	50/3360	160/18639	0.3125	1.73353794642857	3.34272013493806e-05	0.00102225045987059
GO:0140030	modification-dependent protein binding	53/3360	173/18639	0.30635838150289	1.69946841453344	3.62574594107058e-05	0.00107067439827544
GO:0051540	metal cluster binding	29/3360	77/18639	0.376623376623377	2.08925092764379	3.66390478497297e-05	0.00107067439827544
GO:0070063	RNA polymerase binding	24/3360	59/18639	0.406779661016949	2.25653753026634	3.95055288301559e-05	0.00112934283503598
GO:0003727	single-stranded RNA binding	32/3360	89/18639	0.359550561797753	1.99454253611557	4.35873717926979e-05	0.00121951901930634
GO:0061659	ubiquitin-like protein ligase activity	97/3360	372/18639	0.260752688172043	1.44647897465438	6.23590288869414e-05	0.00170837756221517
GO:1990841	promoter-specific chromatin binding	26/3360	68/18639	0.382352941176471	2.12103466386555	6.76661781999952e-05	0.00181593927210191
GO:0031072	heat shock protein binding	42/3360	131/18639	0.320610687022901	1.77853053435114	7.17689886803066e-05	0.00188752440229206
GO:0008276	protein methyltransferase activity	33/3360	95/18639	0.347368421052632	1.92696428571429	7.34056856666912e-05	0.00189271522846469
GO:0140297	DNA-binding transcription factor binding	121/3360	488/18639	0.247950819672131	1.37546289519906	9.29378711682743e-05	0.0023502557805054
GO:0048407	platelet-derived growth factor binding	8/3360	11/18639	0.727272727272727	4.03441558441558	0.000108489294237631	0.00264191522078676
GO:0140537	transcription regulator activator activity	8/3360	11/18639	0.727272727272727	4.03441558441558	0.000108489294237631	0.00264191522078676
GO:0003756	protein disulfide isomerase activity	11/3360	19/18639	0.578947368421053	3.21160714285714	0.000116239112517722	0.00269833326889783
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	11/3360	19/18639	0.578947368421053	3.21160714285714	0.000116239112517722	0.00269833326889783
GO:0051537	2 iron, 2 sulfur cluster binding	14/3360	28/18639	0.5	2.77366071428571	0.00011696197439329	0.00269833326889783
GO:0140101	catalytic activity, acting on a tRNA	43/3360	139/18639	0.309352517985612	1.71607785200411	0.000148005251364855	0.00335563630249628
GO:0000287	magnesium ion binding	64/3360	230/18639	0.278260869565217	1.54360248447205	0.000152847363058093	0.00340668275290496
GO:0060590	ATPase regulator activity	20/3360	49/18639	0.408163265306122	2.26421282798834	0.000161533176086746	0.0035249154521833
GO:0003725	double-stranded RNA binding	27/3360	75/18639	0.36	1.99703571428571	0.000163513188276183	0.0035249154521833
GO:0043024	ribosomal small subunit binding	11/3360	20/18639	0.55	3.05102678571429	0.000216237167835084	0.00458632057585702
GO:0042393	histone binding	67/3360	247/18639	0.271255060728745	1.50473901098901	0.000243763202041886	0.00508807318547746
GO:0003925	G protein activity	21/3360	54/18639	0.388888888888889	2.15729166666667	0.000250718405742269	0.00509626921805126
GO:0140416	transcription regulator inhibitor activity	15/3360	33/18639	0.454545454545455	2.52150974025974	0.000259066065597761	0.00509626921805126
GO:0004386	helicase activity	46/3360	155/18639	0.296774193548387	1.64630184331797	0.000259600252822384	0.00509626921805126
GO:0061630	ubiquitin protein ligase activity	90/3360	353/18639	0.254957507082153	1.41433124241198	0.000259657823277137	0.00509626921805126
GO:0003724	RNA helicase activity	27/3360	77/18639	0.350649350649351	1.9451646567718	0.000269133183965897	0.00520456083698757
GO:0003924	GTPase activity	85/3360	331/18639	0.256797583081571	1.42453873543375	0.00029529684198992	0.00562775865531513
GO:0005048	signal sequence binding	20/3360	51/18639	0.392156862745098	2.17542016806723	0.000306581055047374	0.0057211199077471
GO:0140767	enzyme-substrate adaptor activity	42/3360	139/18639	0.302158273381295	1.6761690647482	0.000308896968403075	0.0057211199077471
GO:0000774	adenyl-nucleotide exchange factor activity	9/3360	15/18639	0.6	3.32839285714286	0.00034765458882308	0.00634952478197708
GO:0061650	ubiquitin-like protein conjugating enzyme activity	17/3360	41/18639	0.414634146341463	2.30010888501742	0.000395462214225029	0.00712373714665634
GO:0042054	histone methyltransferase activity	24/3360	67/18639	0.358208955223881	1.98710021321962	0.000402678819160854	0.00715571144860166
GO:0003713	transcription coactivator activity	68/3360	256/18639	0.265625	1.47350725446429	0.000419761892976601	0.00731403048382153
GO:0019003	GDP binding	26/3360	75/18639	0.346666666666667	1.92307142857143	0.000425230839168556	0.00731403048382153
GO:0008186	ATP-dependent activity, acting on RNA	27/3360	79/18639	0.341772151898734	1.89591998191682	0.000431097739351899	0.00731403048382153
GO:0008135	translation factor activity, RNA binding	28/3360	83/18639	0.337349397590361	1.87138554216867	0.000433836028698159	0.00731403048382153
GO:0001098	basal transcription machinery binding	22/3360	60/18639	0.366666666666667	2.03401785714286	0.000477425140196623	0.00784767574198199
GO:0001099	basal RNA polymerase II transcription machinery binding	22/3360	60/18639	0.366666666666667	2.03401785714286	0.000477425140196623	0.00784767574198199
GO:0016763	pentosyltransferase activity	19/3360	49/18639	0.387755102040816	2.15100218658892	0.000508945991526142	0.0082625182574923
GO:0180051	translation factor activity	28/3360	84/18639	0.333333333333333	1.84910714285714	0.00054027433357289	0.00856128361277884
GO:0000049	tRNA binding	27/3360	80/18639	0.3375	1.87222098214286	0.000540369992289463	0.00856128361277884
GO:0061631	ubiquitin conjugating enzyme activity	15/3360	35/18639	0.428571428571429	2.37742346938776	0.000564925018044329	0.0088437666515273
GO:0008139	nuclear localization sequence binding	12/3360	25/18639	0.48	2.66271428571429	0.000580995969245176	0.00898834940655772
GO:0016279	protein-lysine N-methyltransferase activity	24/3360	69/18639	0.347826086956522	1.92950310559006	0.000659180272272637	0.00987052763842418
GO:0030515	snoRNA binding	14/3360	32/18639	0.4375	2.426953125	0.000668043315452283	0.00987052763842418
GO:0051059	NF-kappaB binding	14/3360	32/18639	0.4375	2.426953125	0.000668043315452283	0.00987052763842418
GO:0070717	poly-purine tract binding	14/3360	32/18639	0.4375	2.426953125	0.000668043315452283	0.00987052763842418
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	20/3360	54/18639	0.37037037037037	2.05456349206349	0.000732701926596059	0.0107055892608202
GO:0016278	lysine N-methyltransferase activity	24/3360	70/18639	0.342857142857143	1.9019387755102	0.000833884762829914	0.0120500930013334
GO:0106310	protein serine kinase activity	89/3360	361/18639	0.246537396121884	1.36762218045113	0.000892264859080736	0.0127535683662084
GO:0032182	ubiquitin-like protein binding	36/3360	120/18639	0.3	1.66419642857143	0.000925112352781746	0.0130423742246053
GO:0015036	disulfide oxidoreductase activity	16/3360	40/18639	0.4	2.21892857142857	0.000932306598564942	0.0130423742246053
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	86/3360	349/18639	0.246418338108883	1.36696172738436	0.00109435041901156	0.015148113694739
GO:0061608	nuclear import signal receptor activity	10/3360	20/18639	0.5	2.77366071428571	0.00112786123034023	0.0154493491447646
GO:0008187	poly-pyrimidine tract binding	13/3360	30/18639	0.433333333333333	2.40383928571429	0.00115413319158138	0.0156462386281393
GO:1990825	sequence-specific mRNA binding	8/3360	14/18639	0.571428571428571	3.16989795918367	0.00117716778427372	0.0157956697583668
GO:0140034	methylation-dependent protein binding	25/3360	76/18639	0.328947368421053	1.82477678571429	0.00129665504131942	0.0171912553269396
GO:0030145	manganese ion binding	23/3360	68/18639	0.338235294117647	1.87629989495798	0.00130731979672545	0.0171912553269396
GO:0015035	protein-disulfide reductase activity	14/3360	34/18639	0.411764705882353	2.28419117647059	0.00137720607672433	0.0179288875979372
GO:0046915	transition metal ion transmembrane transporter activity	17/3360	45/18639	0.377777777777778	2.09565476190476	0.00139068177565749	0.0179288875979372
GO:0042826	histone deacetylase binding	37/3360	127/18639	0.291338582677165	1.61614876265467	0.00143164100491929	0.0182777468103774
GO:0016860	intramolecular oxidoreductase activity	19/3360	53/18639	0.358490566037736	1.98866239892183	0.00154725498516314	0.0193775267189479
GO:0140296	general transcription initiation factor binding	19/3360	53/18639	0.358490566037736	1.98866239892183	0.00154725498516314	0.0193775267189479
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	37/3360	128/18639	0.2890625	1.60352260044643	0.00167005374032474	0.020718119514406
GO:0043175	RNA polymerase core enzyme binding	16/3360	42/18639	0.380952380952381	2.11326530612245	0.00172026893978788	0.0209475809063568
GO:0031267	small GTPase binding	71/3360	283/18639	0.250883392226148	1.3917308177688	0.00172573461489339	0.0209475809063568
GO:0019887	protein kinase regulator activity	65/3360	255/18639	0.254901960784314	1.4140231092437	0.00173633940592615	0.0209475809063568
GO:0051287	NAD binding	19/3360	54/18639	0.351851851851852	1.95183531746032	0.00198944093124241	0.0235416883172656
GO:0035064	methylated histone binding	24/3360	74/18639	0.324324324324324	1.79913127413127	0.00199245404377665	0.0235416883172656
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	9/3360	18/18639	0.5	2.77366071428571	0.00200507155249715	0.0235416883172656
GO:0005049	nuclear export signal receptor activity	7/3360	12/18639	0.583333333333333	3.2359375	0.00208113869528977	0.023797368559183
GO:0016273	arginine N-methyltransferase activity	7/3360	12/18639	0.583333333333333	3.2359375	0.00208113869528977	0.023797368559183
GO:0016274	protein-arginine N-methyltransferase activity	7/3360	12/18639	0.583333333333333	3.2359375	0.00208113869528977	0.023797368559183
GO:0017056	structural constituent of nuclear pore	11/3360	25/18639	0.44	2.44082142857143	0.00237105299759641	0.026878747343442
GO:0140938	histone H3 methyltransferase activity	17/3360	47/18639	0.361702127659574	2.00647796352584	0.00240545688352192	0.0270199482480197
GO:0051020	GTPase binding	77/3360	315/18639	0.244444444444444	1.3560119047619	0.00242460372111507	0.0270199482480197
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	35/3360	122/18639	0.286885245901639	1.59144467213115	0.00251996472351897	0.0277724085089077
GO:0019207	kinase regulator activity	71/3360	287/18639	0.247386759581882	1.37233387257342	0.00253436427457713	0.0277724085089077
GO:0044390	ubiquitin-like protein conjugating enzyme binding	14/3360	36/18639	0.388888888888889	2.15729166666667	0.00262529111498897	0.0285310563323182
GO:0005521	lamin binding	8/3360	16/18639	0.5	2.77366071428571	0.00358278659280355	0.0386031990826596
GO:0045296	cadherin binding	80/3360	334/18639	0.239520958083832	1.3286997433704	0.00361978975973101	0.0386031990826596
GO:0008641	ubiquitin-like modifier activating enzyme activity	6/3360	10/18639	0.6	3.32839285714286	0.00368842759188503	0.0386031990826596
GO:1905394	retromer complex binding	6/3360	10/18639	0.6	3.32839285714286	0.00368842759188503	0.0386031990826596
GO:0043539	protein serine/threonine kinase activator activity	23/3360	73/18639	0.315068493150685	1.7477862035225	0.00369886166115218	0.0386031990826596
GO:0016877	ligase activity, forming carbon-sulfur bonds	15/3360	41/18639	0.365853658536585	2.02950783972125	0.0037466239945855	0.0387937838809443
GO:0031624	ubiquitin conjugating enzyme binding	12/3360	30/18639	0.4	2.21892857142857	0.00398118523103036	0.0405833998356971
GO:0035925	mRNA 3'-UTR AU-rich region binding	12/3360	30/18639	0.4	2.21892857142857	0.00398118523103036	0.0405833998356971
GO:0003697	single-stranded DNA binding	34/3360	121/18639	0.28099173553719	1.55875147579693	0.00413845225405331	0.0418620362621546
GO:0140996	histone H3 kinase activity	84/3360	357/18639	0.235294117647059	1.30525210084034	0.00485696609009432	0.0474183043280755
GO:0016859	cis-trans isomerase activity	15/3360	42/18639	0.357142857142857	1.9811862244898	0.00487237680280637	0.0474183043280755
GO:0005385	zinc ion transmembrane transporter activity	11/3360	27/18639	0.407407407407407	2.26001984126984	0.00488218085812462	0.0474183043280755
GO:0008266	poly(U) RNA binding	11/3360	27/18639	0.407407407407407	2.26001984126984	0.00488218085812462	0.0474183043280755
GO:0031418	L-ascorbic acid binding	9/3360	20/18639	0.45	2.49629464285714	0.00490409839438651	0.0474183043280755
GO:0140939	histone H4 methyltransferase activity	9/3360	20/18639	0.45	2.49629464285714	0.00490409839438651	0.0474183043280755
GO:0141003	histone H2AX kinase activity	83/3360	354/18639	0.234463276836158	1.3006431598063	0.00560920034194017	0.0538401346689877
GO:0004029	aldehyde dehydrogenase (NAD+) activity	8/3360	17/18639	0.470588235294118	2.61050420168067	0.00570766839659592	0.0539970067735513
GO:0051787	misfolded protein binding	8/3360	17/18639	0.470588235294118	2.61050420168067	0.00570766839659592	0.0539970067735513
GO:0008173	RNA methyltransferase activity	21/3360	67/18639	0.313432835820896	1.73871268656716	0.0057714410523375	0.0542103213130272
GO:0004527	exonuclease activity	25/3360	84/18639	0.297619047619048	1.65098852040816	0.00584188830982714	0.0544828590597354
GO:0001091	RNA polymerase II general transcription initiation factor binding	10/3360	24/18639	0.416666666666667	2.31138392857143	0.00596003718763341	0.055193302124915
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	14/3360	39/18639	0.358974358974359	1.99134615384615	0.00610865637346078	0.0558004105237885
GO:0035173	histone kinase activity	84/3360	360/18639	0.233333333333333	1.294375	0.00611046320564681	0.0558004105237885
GO:0030544	Hsp70 protein binding	17/3360	51/18639	0.333333333333333	1.84910714285714	0.00629671381603888	0.057104680469594
GO:0097493	structural molecule activity conferring elasticity	6/3360	11/18639	0.545454545454545	3.02581168831169	0.00688231631987743	0.0619879860317728
GO:0140223	general transcription initiation factor activity	21/3360	68/18639	0.308823529411765	1.71314338235294	0.00696046799633156	0.0622654109875919
GO:0140857	histone H3T45 kinase activity	60/3360	246/18639	0.24390243902439	1.35300522648084	0.00713876971953659	0.0634289336566933
GO:0000993	RNA polymerase II complex binding	13/3360	36/18639	0.361111111111111	2.0031994047619	0.00766655938562977	0.0663258262638365
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	13/3360	36/18639	0.361111111111111	2.0031994047619	0.00766655938562977	0.0663258262638365
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	13/3360	36/18639	0.361111111111111	2.0031994047619	0.00766655938562977	0.0663258262638365
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	13/3360	36/18639	0.361111111111111	2.0031994047619	0.00766655938562977	0.0663258262638365
GO:0035403	histone H3T6 kinase activity	60/3360	247/18639	0.242914979757085	1.34752747252747	0.00780868200133482	0.0669417141672192
GO:0004532	RNA exonuclease activity	14/3360	40/18639	0.35	1.9415625	0.00786725051359538	0.0669417141672192
GO:0001223	transcription coactivator binding	15/3360	44/18639	0.340909090909091	1.89113230519481	0.00794137445633932	0.0669417141672192
GO:0030020	extracellular matrix structural constituent conferring tensile strength	15/3360	44/18639	0.340909090909091	1.89113230519481	0.00794137445633932	0.0669417141672192
GO:0004674	protein serine/threonine kinase activity	98/3360	433/18639	0.226327944572748	1.25551385681293	0.00815607311249571	0.0683136060059354
GO:0002039	p53 binding	21/3360	69/18639	0.304347826086957	1.6883152173913	0.00834206382219629	0.0694292020644818
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	19/3360	61/18639	0.311475409836066	1.72785421545667	0.00903263348956457	0.0718857445254353
GO:0043130	ubiquitin binding	28/3360	100/18639	0.28	1.55325	0.00914581541081623	0.0718857445254353
GO:0031491	nucleosome binding	22/3360	74/18639	0.297297297297297	1.64920366795367	0.0094644516658716	0.0718857445254353
GO:0016251	RNA polymerase II general transcription initiation factor activity	17/3360	53/18639	0.320754716981132	1.7793295148248	0.00961322646431334	0.0718857445254353
GO:0071889	14-3-3 protein binding	12/3360	33/18639	0.363636363636364	2.01720779220779	0.00963260540996768	0.0718857445254353
GO:0016407	acetyltransferase activity	27/3360	96/18639	0.28125	1.56018415178571	0.00972888177613893	0.0718857445254353
GO:0051539	4 iron, 4 sulfur cluster binding	15/3360	45/18639	0.333333333333333	1.84910714285714	0.00996706232667242	0.0718857445254353
GO:0004676	3-phosphoinositide-dependent protein kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0004711	ribosomal protein S6 kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0035175	histone H3S10 kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0035979	histone H2AXS139 kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0044022	histone H3S28 kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0044023	histone H4S1 kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0044024	histone H2AS1 kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0044025	histone H2BS14 kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0072354	histone H3T3 kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0072371	histone H2AS121 kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0072518	Rho-dependent protein serine/threonine kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0140823	histone H2BS36 kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0140855	histone H3S57 kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0140995	histone H2A kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0140997	histone H4 kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0140998	histone H2B kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:1990244	histone H2AT120 kinase activity	59/3360	245/18639	0.240816326530612	1.33588556851312	0.00997624107465012	0.0718857445254353
GO:0140318	protein transporter activity	14/3360	41/18639	0.341463414634146	1.89420731707317	0.0100038716716005	0.0718857445254353
GO:0034062	5'-3' RNA polymerase activity	9/3360	22/18639	0.409090909090909	2.26935876623377	0.0103029491586126	0.0728407427073957
GO:0097747	RNA polymerase activity	9/3360	22/18639	0.409090909090909	2.26935876623377	0.0103029491586126	0.0728407427073957
GO:0140035	ubiquitin-like protein reader activity	9/3360	22/18639	0.409090909090909	2.26935876623377	0.0103029491586126	0.0728407427073957
GO:0004677	DNA-dependent protein kinase activity	59/3360	246/18639	0.239837398373984	1.33045513937282	0.0108714860476538	0.0764492200677262
GO:0008408	3'-5' exonuclease activity	18/3360	58/18639	0.310344827586207	1.72158251231527	0.0113149829782544	0.0790272671945775
GO:0008143	poly(A) binding	10/3360	26/18639	0.384615384615385	2.13358516483517	0.0114183884159466	0.0790272671945775
GO:0097602	cullin family protein binding	10/3360	26/18639	0.384615384615385	2.13358516483517	0.0114183884159466	0.0790272671945775
GO:0031543	peptidyl-proline dioxygenase activity	6/3360	12/18639	0.5	2.77366071428571	0.0116834939444651	0.080310744019872
GO:0140463	chromatin-protein adaptor activity	17/3360	54/18639	0.314814814814815	1.74637896825397	0.0117259793549927	0.080310744019872
GO:0035402	histone H3T11 kinase activity	59/3360	247/18639	0.238866396761134	1.32506868131868	0.0118326851898497	0.0806216633401675
GO:0015605	organophosphate ester transmembrane transporter activity	16/3360	50/18639	0.32	1.77514285714286	0.0120878505814254	0.0817156446768324
GO:0070566	adenylyltransferase activity	11/3360	30/18639	0.366666666666667	2.03401785714286	0.0121175290585417	0.0817156446768324
GO:0008175	tRNA methyltransferase activity	12/3360	34/18639	0.352941176470588	1.9578781512605	0.0124936471304562	0.0838221733497446
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	13/3360	38/18639	0.342105263157895	1.89776785714286	0.0126239140184171	0.0842124990822241
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	58/3360	243/18639	0.238683127572016	1.32405202821869	0.0126799048047759	0.0842124990822241
GO:0004679	AMP-activated protein kinase activity	59/3360	248/18639	0.237903225806452	1.3197256624424	0.0128633977883095	0.0850018497066685
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	9/3360	23/18639	0.391304347826087	2.17069099378882	0.014267127197772	0.0938063613253508
GO:0008320	protein transmembrane transporter activity	10/3360	27/18639	0.37037037037037	2.05456349206349	0.0152632163911359	0.0998563659420084
GO:0043023	ribosomal large subunit binding	7/3360	16/18639	0.4375	2.426953125	0.0153846577028617	0.100152598412194
GO:0000175	3'-5'-RNA exonuclease activity	12/3360	35/18639	0.342857142857143	1.9019387755102	0.0159619318599067	0.102891864685183
GO:0140566	histone reader activity	12/3360	35/18639	0.342857142857143	1.9019387755102	0.0159619318599067	0.102891864685183
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	8/3360	20/18639	0.4	2.21892857142857	0.0178043644342117	0.114208484053602
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	6/3360	13/18639	0.461538461538462	2.5603021978022	0.0184320741952832	0.116529699840372
GO:0140666	annealing activity	6/3360	13/18639	0.461538461538462	2.5603021978022	0.0184320741952832	0.116529699840372
GO:0140852	histone ubiquitin ligase activity	6/3360	13/18639	0.461538461538462	2.5603021978022	0.0184320741952832	0.116529699840372
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	15/3360	48/18639	0.3125	1.73353794642857	0.0185420125884875	0.116663859109383
GO:0048029	monosaccharide binding	21/3360	74/18639	0.283783783783784	1.57423986486486	0.0189218154074955	0.118486606004079
GO:0003954	NADH dehydrogenase activity	14/3360	44/18639	0.318181818181818	1.76505681818182	0.0191988956604172	0.119413048505045
GO:0048027	mRNA 5'-UTR binding	9/3360	24/18639	0.375	2.08024553571429	0.0192513812038551	0.119413048505045
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	13/3360	40/18639	0.325	1.80287946428571	0.0197402761836693	0.120737038053605
GO:0061791	GTPase motor activity	13/3360	40/18639	0.325	1.80287946428571	0.0197402761836693	0.120737038053605
GO:1990606	membrane scission GTPase motor activity	13/3360	40/18639	0.325	1.80287946428571	0.0197402761836693	0.120737038053605
GO:0022884	macromolecule transmembrane transporter activity	11/3360	32/18639	0.34375	1.90689174107143	0.0202293093517235	0.123155286099613
GO:0019209	kinase activator activity	37/3360	148/18639	0.25	1.38683035714286	0.0205156482638676	0.12432293763588
GO:0030295	protein kinase activator activity	35/3360	139/18639	0.251798561151079	1.39680755395683	0.0213932529842699	0.125763546419492
GO:0005381	iron ion transmembrane transporter activity	5/3360	10/18639	0.5	2.77366071428571	0.021422839846362	0.125763546419492
GO:0005528	FK506 binding	5/3360	10/18639	0.5	2.77366071428571	0.021422839846362	0.125763546419492
GO:0015924	mannosyl-oligosaccharide mannosidase activity	5/3360	10/18639	0.5	2.77366071428571	0.021422839846362	0.125763546419492
GO:0016783	sulfurtransferase activity	5/3360	10/18639	0.5	2.77366071428571	0.021422839846362	0.125763546419492
GO:0140940	histone H2A methyltransferase activity	5/3360	10/18639	0.5	2.77366071428571	0.021422839846362	0.125763546419492
GO:1990259	histone H2AQ104 methyltransferase activity	5/3360	10/18639	0.5	2.77366071428571	0.021422839846362	0.125763546419492
GO:0004659	prenyltransferase activity	7/3360	17/18639	0.411764705882353	2.28419117647059	0.0221585502172478	0.128931387326022
GO:1990226	histone methyltransferase binding	7/3360	17/18639	0.411764705882353	2.28419117647059	0.0221585502172478	0.128931387326022
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	8/3360	21/18639	0.380952380952381	2.11326530612245	0.0243137898476235	0.14023084934046
GO:0035613	RNA stem-loop binding	8/3360	21/18639	0.380952380952381	2.11326530612245	0.0243137898476235	0.14023084934046
GO:0017025	TBP-class protein binding	9/3360	25/18639	0.36	1.99703571428571	0.025381893141716	0.145282666603345
GO:0017069	snRNA binding	16/3360	54/18639	0.296296296296296	1.64365079365079	0.0254106565161744	0.145282666603345
GO:0019783	ubiquitin-like protein peptidase activity	32/3360	127/18639	0.251968503937008	1.39775028121485	0.0266161320302644	0.15151607627618
GO:0019210	kinase inhibitor activity	24/3360	90/18639	0.266666666666667	1.47928571428571	0.0268241196639483	0.152041885164189
GO:0030983	mismatched DNA binding	6/3360	14/18639	0.428571428571429	2.37742346938776	0.0274237802021852	0.154773695132504
GO:0004518	nuclease activity	49/3360	209/18639	0.23444976076555	1.30056818181818	0.0279143415690543	0.154860916261443
GO:0016791	phosphatase activity	62/3360	273/18639	0.227106227106227	1.25983124018838	0.0281734817119814	0.154860916261443
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	14/3360	46/18639	0.304347826086957	1.6883152173913	0.0281760269128341	0.154860916261443
GO:0016922	nuclear receptor binding	34/3360	137/18639	0.248175182481752	1.37670750782065	0.0282222205820888	0.154860916261443
GO:0031593	polyubiquitin modification-dependent protein binding	17/3360	59/18639	0.288135593220339	1.59838075060533	0.0282554844783813	0.154860916261443
GO:0070888	E-box binding	17/3360	59/18639	0.288135593220339	1.59838075060533	0.0282554844783813	0.154860916261443
GO:0001217	DNA-binding transcription repressor activity	63/3360	278/18639	0.226618705035971	1.25712679856115	0.0282635892796551	0.154860916261443
GO:0051879	Hsp90 protein binding	13/3360	42/18639	0.30952380952381	1.71702806122449	0.0295016013559132	0.16097346797936
GO:0000400	four-way junction DNA binding	7/3360	18/18639	0.388888888888889	2.15729166666667	0.0307423348006669	0.166362840587971
GO:0003746	translation elongation factor activity	7/3360	18/18639	0.388888888888889	2.15729166666667	0.0307423348006669	0.166362840587971
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	11/3360	34/18639	0.323529411764706	1.79472163865546	0.0317613202840621	0.170826370793343
GO:0003743	translation initiation factor activity	15/3360	51/18639	0.294117647058824	1.63156512605042	0.0318269664215734	0.170826370793343
GO:0016874	ligase activity	40/3360	167/18639	0.239520958083832	1.3286997433704	0.0319702314560577	0.17089778197039
GO:0015215	nucleotide transmembrane transporter activity	10/3360	30/18639	0.333333333333333	1.84910714285714	0.0325021062956469	0.173037529468727
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	17/3360	60/18639	0.283333333333333	1.57174107142857	0.0330059667259807	0.175011476793002
GO:0101005	deubiquitinase activity	29/3360	115/18639	0.252173913043478	1.39888975155279	0.0331978648323934	0.175322057247379
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	5/3360	11/18639	0.454545454545455	2.52150974025974	0.0335399427850992	0.175717230129106
GO:0032404	mismatch repair complex binding	5/3360	11/18639	0.454545454545455	2.52150974025974	0.0335399427850992	0.175717230129106
GO:0004712	protein serine/threonine/tyrosine kinase activity	13/3360	43/18639	0.302325581395349	1.67709717607973	0.0355182805354328	0.18534340834958
GO:0019843	rRNA binding	18/3360	65/18639	0.276923076923077	1.53618131868132	0.0357763033765851	0.185951932569998
GO:0009055	electron transfer activity	29/3360	116/18639	0.25	1.38683035714286	0.0368776816846244	0.190921855965673
GO:0046332	SMAD binding	21/3360	79/18639	0.265822784810127	1.47460443037975	0.0378139060023261	0.195001123110035
GO:0004559	alpha-mannosidase activity	6/3360	15/18639	0.4	2.21892857142857	0.038892074275501	0.198792865264924
GO:0061578	K63-linked deubiquitinase activity	6/3360	15/18639	0.4	2.21892857142857	0.038892074275501	0.198792865264924
GO:0043015	gamma-tubulin binding	11/3360	35/18639	0.314285714285714	1.74344387755102	0.0390027066451333	0.198792865264924
GO:0004860	protein kinase inhibitor activity	22/3360	84/18639	0.261904761904762	1.45286989795918	0.0397775134192882	0.201959189754301
GO:0002020	protease binding	33/3360	136/18639	0.242647058823529	1.3460412289916	0.0405998024921807	0.205341308758529
GO:0140036	ubiquitin-modified protein reader activity	7/3360	19/18639	0.368421052631579	2.04375	0.0412995462570583	0.207285890565007
GO:1990380	K48-linked deubiquitinase activity	7/3360	19/18639	0.368421052631579	2.04375	0.0412995462570583	0.207285890565007
GO:0001671	ATPase activator activity	9/3360	27/18639	0.333333333333333	1.84910714285714	0.041529897034529	0.207649485172645
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	8/3360	23/18639	0.347826086956522	1.92950310559006	0.0419481751026778	0.208946402500081
GO:0001046	core promoter sequence-specific DNA binding	13/3360	44/18639	0.295454545454545	1.63898133116883	0.042361893547536	0.210210905717018
GO:0004843	cysteine-type deubiquitinase activity	27/3360	108/18639	0.25	1.38683035714286	0.0428378572037445	0.211773617379414
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	16/3360	58/18639	0.275862068965517	1.53029556650246	0.0474923179007365	0.228323063570895
GO:0033192	calmodulin-dependent protein phosphatase activity	21/3360	81/18639	0.259259259259259	1.43819444444444	0.0483604003343957	0.228323063570895
GO:0140791	histone H2AXS140 phosphatase activity	21/3360	81/18639	0.259259259259259	1.43819444444444	0.0483604003343957	0.228323063570895
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	21/3360	81/18639	0.259259259259259	1.43819444444444	0.0483604003343957	0.228323063570895
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	21/3360	81/18639	0.259259259259259	1.43819444444444	0.0483604003343957	0.228323063570895
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	21/3360	81/18639	0.259259259259259	1.43819444444444	0.0483604003343957	0.228323063570895
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	21/3360	81/18639	0.259259259259259	1.43819444444444	0.0483604003343957	0.228323063570895
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	21/3360	81/18639	0.259259259259259	1.43819444444444	0.0483604003343957	0.228323063570895
GO:1990439	MAP kinase serine/threonine phosphatase activity	21/3360	81/18639	0.259259259259259	1.43819444444444	0.0483604003343957	0.228323063570895
GO:0004300	enoyl-CoA hydratase activity	5/3360	12/18639	0.416666666666667	2.31138392857143	0.0491516919569808	0.228323063570895
GO:0005095	GTPase inhibitor activity	5/3360	12/18639	0.416666666666667	2.31138392857143	0.0491516919569808	0.228323063570895
GO:0005527	macrolide binding	5/3360	12/18639	0.416666666666667	2.31138392857143	0.0491516919569808	0.228323063570895
GO:0016423	tRNA (guanine) methyltransferase activity	5/3360	12/18639	0.416666666666667	2.31138392857143	0.0491516919569808	0.228323063570895
GO:0035251	UDP-glucosyltransferase activity	5/3360	12/18639	0.416666666666667	2.31138392857143	0.0491516919569808	0.228323063570895
GO:0036009	protein-glutamine N-methyltransferase activity	5/3360	12/18639	0.416666666666667	2.31138392857143	0.0491516919569808	0.228323063570895
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	5/3360	12/18639	0.416666666666667	2.31138392857143	0.0491516919569808	0.228323063570895
GO:0141221	histone deacetylase activity, hydrolytic mechanism	5/3360	12/18639	0.416666666666667	2.31138392857143	0.0491516919569808	0.228323063570895
GO:0008234	cysteine-type peptidase activity	43/3360	187/18639	0.229946524064171	1.27558728036669	0.0495783899797202	0.228323063570895
GO:0031369	translation initiation factor binding	10/3360	32/18639	0.3125	1.73353794642857	0.049658095955343	0.228323063570895
GO:0043425	bHLH transcription factor binding	10/3360	32/18639	0.3125	1.73353794642857	0.049658095955343	0.228323063570895
GO:0097718	disordered domain specific binding	9/3360	28/18639	0.321428571428571	1.78306760204082	0.0517318672396296	0.237029287178094
GO:0005201	extracellular matrix structural constituent	39/3360	168/18639	0.232142857142857	1.28777104591837	0.0521312492266985	0.238029835878849
GO:0015923	mannosidase activity	6/3360	16/18639	0.375	2.08024553571429	0.0529965242190846	0.239543009644962
GO:0016722	oxidoreductase activity, acting on metal ions	6/3360	16/18639	0.375	2.08024553571429	0.0529965242190846	0.239543009644962
GO:0035035	histone acetyltransferase binding	8/3360	24/18639	0.333333333333333	1.84910714285714	0.0532965720520891	0.239543009644962
GO:0140612	DNA damage sensor activity	8/3360	24/18639	0.333333333333333	1.84910714285714	0.0532965720520891	0.239543009644962
GO:0008137	NADH dehydrogenase (ubiquinone) activity	12/3360	41/18639	0.292682926829268	1.623606271777	0.0533734614646189	0.239543009644962
GO:0000339	RNA cap binding	7/3360	20/18639	0.35	1.9415625	0.0539507980078219	0.241310542109816
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	21/3360	82/18639	0.25609756097561	1.42065548780488	0.0543590643390181	0.241493816235841
GO:0033549	MAP kinase phosphatase activity	21/3360	82/18639	0.25609756097561	1.42065548780488	0.0543590643390181	0.241493816235841
GO:0004713	protein tyrosine kinase activity	33/3360	140/18639	0.235714285714286	1.30758290816327	0.0579996382261121	0.25679974500787
GO:0140311	protein sequestering activity	10/3360	33/18639	0.303030303030303	1.68100649350649	0.0601495892739263	0.265425200990648
GO:0008080	N-acetyltransferase activity	18/3360	69/18639	0.260869565217391	1.44712732919255	0.0608539889649807	0.266792683091398
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	21/3360	83/18639	0.253012048192771	1.40353915662651	0.060865250895376	0.266792683091398
GO:0019838	growth factor binding	32/3360	136/18639	0.235294117647059	1.30525210084034	0.0624359108522494	0.272234796980456
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	16/3360	60/18639	0.266666666666667	1.47928571428571	0.0625208431088195	0.272234796980456
GO:0035198	miRNA binding	12/3360	42/18639	0.285714285714286	1.58494897959184	0.0629222055081013	0.273078218624268
GO:0003678	DNA helicase activity	19/3360	74/18639	0.256756756756757	1.42431225868726	0.063471283255149	0.274555057501713
GO:0042578	phosphoric ester hydrolase activity	77/3360	363/18639	0.212121212121212	1.17670454545455	0.0657148934289776	0.283328147079035
GO:0019211	phosphatase activator activity	8/3360	25/18639	0.32	1.77514285714286	0.0664328915393234	0.284557825323161
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	8/3360	25/18639	0.32	1.77514285714286	0.0664328915393234	0.284557825323161
GO:0043531	ADP binding	11/3360	38/18639	0.289473684210526	1.60580357142857	0.067358993351739	0.28527328784106
GO:0017018	myosin phosphatase activity	21/3360	84/18639	0.25	1.38683035714286	0.0678944967207386	0.28527328784106
GO:0140359	ABC-type transporter activity	13/3360	47/18639	0.276595744680851	1.53436550151976	0.0682781626808295	0.28527328784106
GO:1990518	single-stranded 3'-5' DNA helicase activity	13/3360	47/18639	0.276595744680851	1.53436550151976	0.0682781626808295	0.28527328784106
GO:0004535	poly(A)-specific ribonuclease activity	5/3360	13/18639	0.384615384615385	2.13358516483517	0.0683514530580418	0.28527328784106
GO:0097157	pre-mRNA intronic binding	5/3360	13/18639	0.384615384615385	2.13358516483517	0.0683514530580418	0.28527328784106
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	5/3360	13/18639	0.384615384615385	2.13358516483517	0.0683514530580418	0.28527328784106
GO:0005123	death receptor binding	7/3360	21/18639	0.333333333333333	1.84910714285714	0.068769302087921	0.28527328784106
GO:0009931	calcium-dependent protein serine/threonine kinase activity	7/3360	21/18639	0.333333333333333	1.84910714285714	0.068769302087921	0.28527328784106
GO:0072542	protein phosphatase activator activity	7/3360	21/18639	0.333333333333333	1.84910714285714	0.068769302087921	0.28527328784106
GO:0004549	tRNA-specific ribonuclease activity	6/3360	17/18639	0.352941176470588	1.9578781512605	0.0698172373109957	0.287804598946581
GO:0048038	quinone binding	6/3360	17/18639	0.352941176470588	1.9578781512605	0.0698172373109957	0.287804598946581
GO:0031490	chromatin DNA binding	30/3360	128/18639	0.234375	1.30015345982143	0.0724199303756009	0.297600651387235
GO:0005080	protein kinase C binding	14/3360	52/18639	0.269230769230769	1.49350961538462	0.0729291919350493	0.298269753962904
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	58/3360	268/18639	0.216417910447761	1.20053971215352	0.0730363960274183	0.298269753962904
GO:0015932	nucleobase-containing compound transmembrane transporter activity	15/3360	57/18639	0.263157894736842	1.45982142857143	0.0769703532037237	0.313362273878937
GO:0016879	ligase activity, forming carbon-nitrogen bonds	13/3360	48/18639	0.270833333333333	1.50239955357143	0.0788179411339668	0.318909515665127
GO:0043138	3'-5' DNA helicase activity	13/3360	48/18639	0.270833333333333	1.50239955357143	0.0788179411339668	0.318909515665127
GO:0015216	purine nucleotide transmembrane transporter activity	8/3360	26/18639	0.307692307692308	1.70686813186813	0.0813922491923272	0.32831536100586
GO:0004222	metalloendopeptidase activity	26/3360	110/18639	0.236363636363636	1.31118506493506	0.0824103160374196	0.331405399355373
GO:0035401	histone H3Y41 kinase activity	27/3360	115/18639	0.234782608695652	1.30241459627329	0.0833250775728976	0.333047042578603
GO:0140801	histone H2AXY142 kinase activity	27/3360	115/18639	0.234782608695652	1.30241459627329	0.0833250775728976	0.333047042578603
GO:0010485	histone H4 acetyltransferase activity	10/3360	35/18639	0.285714285714286	1.58494897959184	0.0851681659028642	0.337722645076244
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	7/3360	22/18639	0.318181818181818	1.76505681818182	0.0857789836163235	0.337722645076244
GO:0050321	tau-protein kinase activity	7/3360	22/18639	0.318181818181818	1.76505681818182	0.0857789836163235	0.337722645076244
GO:0070034	telomerase RNA binding	7/3360	22/18639	0.318181818181818	1.76505681818182	0.0857789836163235	0.337722645076244
GO:0140517	protein-RNA adaptor activity	7/3360	22/18639	0.318181818181818	1.76505681818182	0.0857789836163235	0.337722645076244
GO:0019902	phosphatase binding	42/3360	190/18639	0.221052631578947	1.22625	0.0869450806250812	0.338620793845823
GO:0061980	regulatory RNA binding	15/3360	58/18639	0.258620689655172	1.43465209359606	0.087253388774533	0.338620793845823
GO:0008140	cAMP response element binding protein binding	4/3360	10/18639	0.4	2.21892857142857	0.0886843150089767	0.338620793845823
GO:0008239	dipeptidyl-peptidase activity	4/3360	10/18639	0.4	2.21892857142857	0.0886843150089767	0.338620793845823
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	4/3360	10/18639	0.4	2.21892857142857	0.0886843150089767	0.338620793845823
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	4/3360	10/18639	0.4	2.21892857142857	0.0886843150089767	0.338620793845823
GO:0031996	thioesterase binding	4/3360	10/18639	0.4	2.21892857142857	0.0886843150089767	0.338620793845823
GO:0033204	ribonuclease P RNA binding	4/3360	10/18639	0.4	2.21892857142857	0.0886843150089767	0.338620793845823
GO:0043295	glutathione binding	4/3360	10/18639	0.4	2.21892857142857	0.0886843150089767	0.338620793845823
GO:0043422	protein kinase B binding	4/3360	10/18639	0.4	2.21892857142857	0.0886843150089767	0.338620793845823
GO:0015172	acidic amino acid transmembrane transporter activity	6/3360	18/18639	0.333333333333333	1.84910714285714	0.0893546885661602	0.338620793845823
GO:0070628	proteasome binding	6/3360	18/18639	0.333333333333333	1.84910714285714	0.0893546885661602	0.338620793845823
GO:1990381	ubiquitin-specific protease binding	6/3360	18/18639	0.333333333333333	1.84910714285714	0.0893546885661602	0.338620793845823
GO:0005161	platelet-derived growth factor receptor binding	5/3360	14/18639	0.357142857142857	1.9811862244898	0.0910890490890731	0.339045741460422
GO:0008174	mRNA methyltransferase activity	5/3360	14/18639	0.357142857142857	1.9811862244898	0.0910890490890731	0.339045741460422
GO:0008559	ABC-type xenobiotic transporter activity	5/3360	14/18639	0.357142857142857	1.9811862244898	0.0910890490890731	0.339045741460422
GO:0004540	RNA nuclease activity	28/3360	121/18639	0.231404958677686	1.28367768595041	0.0913779234995958	0.339045741460422
GO:0016878	acid-thiol ligase activity	9/3360	31/18639	0.290322580645161	1.61051267281106	0.0915294587212546	0.339045741460422
GO:0017147	Wnt-protein binding	9/3360	31/18639	0.290322580645161	1.61051267281106	0.0915294587212546	0.339045741460422
GO:0070273	phosphatidylinositol-4-phosphate binding	9/3360	31/18639	0.290322580645161	1.61051267281106	0.0915294587212546	0.339045741460422
GO:0072349	modified amino acid transmembrane transporter activity	9/3360	31/18639	0.290322580645161	1.61051267281106	0.0915294587212546	0.339045741460422
GO:0071949	FAD binding	11/3360	40/18639	0.275	1.52551339285714	0.0921737313057839	0.340473192885129
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	17/3360	68/18639	0.25	1.38683035714286	0.0934885417326237	0.344362555681793
GO:0045505	dynein intermediate chain binding	10/3360	36/18639	0.277777777777778	1.54092261904762	0.0997268198630843	0.36631499474848
GO:0032813	tumor necrosis factor receptor superfamily binding	13/3360	50/18639	0.26	1.44230357142857	0.102853686386582	0.376748182725225
GO:0003684	damaged DNA binding	18/3360	74/18639	0.243243243243243	1.34934845559846	0.106412171322733	0.388700014692761
GO:0140313	molecular sequestering activity	14/3360	55/18639	0.254545454545455	1.41204545454545	0.106915690484166	0.389457432096063
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	49/3360	229/18639	0.213973799126638	1.18698144104804	0.107502617314237	0.39051365129343
GO:0005520	insulin-like growth factor binding	6/3360	19/18639	0.315789473684211	1.75178571428571	0.111533985016515	0.402931841474497
GO:0046527	glucosyltransferase activity	6/3360	19/18639	0.315789473684211	1.75178571428571	0.111533985016515	0.402931841474497
GO:0160215	deacylase activity	16/3360	65/18639	0.246153846153846	1.36549450549451	0.113165498681505	0.405274182254662
GO:0019903	protein phosphatase binding	32/3360	144/18639	0.222222222222222	1.2327380952381	0.115570674465725	0.405274182254662
GO:0016830	carbon-carbon lyase activity	13/3360	51/18639	0.254901960784314	1.4140231092437	0.116353387751934	0.405274182254662
GO:0019789	SUMO transferase activity	8/3360	28/18639	0.285714285714286	1.58494897959184	0.116754209561161	0.405274182254662
GO:0046966	nuclear thyroid hormone receptor binding	8/3360	28/18639	0.285714285714286	1.58494897959184	0.116754209561161	0.405274182254662
GO:0051019	mitogen-activated protein kinase binding	8/3360	28/18639	0.285714285714286	1.58494897959184	0.116754209561161	0.405274182254662
GO:0141052	histone H3 demethylase activity	8/3360	28/18639	0.285714285714286	1.58494897959184	0.116754209561161	0.405274182254662
GO:0015556	C4-dicarboxylate transmembrane transporter activity	5/3360	15/18639	0.333333333333333	1.84910714285714	0.117187536495859	0.405274182254662
GO:0140776	protein-containing complex destabilizing activity	5/3360	15/18639	0.333333333333333	1.84910714285714	0.117187536495859	0.405274182254662
GO:0141050	histone H3K deacetylase activity	5/3360	15/18639	0.333333333333333	1.84910714285714	0.117187536495859	0.405274182254662
GO:0141051	histone H4K deacetylase activity	5/3360	15/18639	0.333333333333333	1.84910714285714	0.117187536495859	0.405274182254662
GO:0000099	sulfur amino acid transmembrane transporter activity	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0005536	D-glucose binding	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0010854	adenylate cyclase regulator activity	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0032050	clathrin heavy chain binding	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0034511	U3 snoRNA binding	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0035252	UDP-xylosyltransferase activity	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0042285	xylosyltransferase activity	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0070990	snRNP binding	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0140031	phosphorylation-dependent protein binding	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0180030	inositol phosphate kinase activity	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:1900750	oligopeptide binding	4/3360	11/18639	0.363636363636364	2.01720779220779	0.120195384851192	0.405274182254662
GO:0048487	beta-tubulin binding	11/3360	42/18639	0.261904761904762	1.45286989795918	0.121828277735734	0.409729373970563
GO:0061749	forked DNA-dependent helicase activity	12/3360	47/18639	0.25531914893617	1.41633738601824	0.126807302764679	0.425386742692737
GO:0042887	amide transmembrane transporter activity	10/3360	38/18639	0.263157894736842	1.45982142857143	0.132886959755851	0.443429813119905
GO:0044325	transmembrane transporter binding	30/3360	136/18639	0.220588235294118	1.22367384453782	0.133197548427652	0.443429813119905
GO:0140789	histone phosphatase activity	30/3360	136/18639	0.220588235294118	1.22367384453782	0.133197548427652	0.443429813119905
GO:0016004	phospholipase activator activity	6/3360	20/18639	0.3	1.66419642857143	0.136212493734526	0.448920875340606
GO:0016408	C-acyltransferase activity	6/3360	20/18639	0.3	1.66419642857143	0.136212493734526	0.448920875340606
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	6/3360	20/18639	0.3	1.66419642857143	0.136212493734526	0.448920875340606
GO:0140664	ATP-dependent DNA damage sensor activity	6/3360	20/18639	0.3	1.66419642857143	0.136212493734526	0.448920875340606
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	8/3360	29/18639	0.275862068965517	1.53029556650246	0.137063262251132	0.449471795162689
GO:0097472	cyclin-dependent protein kinase activity	8/3360	29/18639	0.275862068965517	1.53029556650246	0.137063262251132	0.449471795162689
GO:0009378	four-way junction helicase activity	12/3360	48/18639	0.25	1.38683035714286	0.142803756641583	0.46045533299965
GO:0036121	double-stranded DNA helicase activity	12/3360	48/18639	0.25	1.38683035714286	0.142803756641583	0.46045533299965
GO:0019208	phosphatase regulator activity	26/3360	117/18639	0.222222222222222	1.2327380952381	0.144207258049612	0.46045533299965
GO:0016831	carboxy-lyase activity	9/3360	34/18639	0.264705882352941	1.46840861344538	0.145210619372398	0.46045533299965
GO:0090482	vitamin transmembrane transporter activity	9/3360	34/18639	0.264705882352941	1.46840861344538	0.145210619372398	0.46045533299965
GO:0034212	protein N-acetyltransferase activity	13/3360	53/18639	0.245283018867925	1.36066374663073	0.146256827345422	0.46045533299965
GO:0000062	fatty-acyl-CoA binding	5/3360	16/18639	0.3125	1.73353794642857	0.146365269348938	0.46045533299965
GO:0003688	DNA replication origin binding	5/3360	16/18639	0.3125	1.73353794642857	0.146365269348938	0.46045533299965
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/3360	16/18639	0.3125	1.73353794642857	0.146365269348938	0.46045533299965
GO:0004708	MAP kinase kinase activity	5/3360	16/18639	0.3125	1.73353794642857	0.146365269348938	0.46045533299965
GO:0008142	oxysterol binding	5/3360	16/18639	0.3125	1.73353794642857	0.146365269348938	0.46045533299965
GO:0015562	efflux transmembrane transporter activity	5/3360	16/18639	0.3125	1.73353794642857	0.146365269348938	0.46045533299965
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	5/3360	16/18639	0.3125	1.73353794642857	0.146365269348938	0.46045533299965
GO:0017070	U6 snRNA binding	5/3360	16/18639	0.3125	1.73353794642857	0.146365269348938	0.46045533299965
GO:0030275	LRR domain binding	5/3360	16/18639	0.3125	1.73353794642857	0.146365269348938	0.46045533299965
GO:0031435	mitogen-activated protein kinase kinase kinase binding	5/3360	16/18639	0.3125	1.73353794642857	0.146365269348938	0.46045533299965
GO:0070411	I-SMAD binding	5/3360	16/18639	0.3125	1.73353794642857	0.146365269348938	0.46045533299965
GO:0017116	single-stranded DNA helicase activity	14/3360	58/18639	0.241379310344828	1.33900862068966	0.14897562928897	0.467548812684953
GO:0000217	DNA secondary structure binding	10/3360	39/18639	0.256410256410256	1.42239010989011	0.151413346279919	0.472094792095022
GO:0016776	phosphotransferase activity, phosphate group as acceptor	10/3360	39/18639	0.256410256410256	1.42239010989011	0.151413346279919	0.472094792095022
GO:0008237	metallopeptidase activity	39/3360	184/18639	0.21195652173913	1.17579095496894	0.152210937891738	0.472094792095022
GO:0016757	glycosyltransferase activity	55/3360	267/18639	0.205992509363296	1.14270666131621	0.153627491660101	0.472094792095022
GO:0000340	RNA 7-methylguanosine cap binding	4/3360	12/18639	0.333333333333333	1.84910714285714	0.155717231298298	0.472094792095022
GO:0000995	RNA polymerase III general transcription initiation factor activity	4/3360	12/18639	0.333333333333333	1.84910714285714	0.155717231298298	0.472094792095022
GO:0004526	ribonuclease P activity	4/3360	12/18639	0.333333333333333	1.84910714285714	0.155717231298298	0.472094792095022
GO:0035259	nuclear glucocorticoid receptor binding	4/3360	12/18639	0.333333333333333	1.84910714285714	0.155717231298298	0.472094792095022
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	4/3360	12/18639	0.333333333333333	1.84910714285714	0.155717231298298	0.472094792095022
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	4/3360	12/18639	0.333333333333333	1.84910714285714	0.155717231298298	0.472094792095022
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	4/3360	12/18639	0.333333333333333	1.84910714285714	0.155717231298298	0.472094792095022
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	4/3360	12/18639	0.333333333333333	1.84910714285714	0.155717231298298	0.472094792095022
GO:1990817	poly(A) RNA polymerase activity	4/3360	12/18639	0.333333333333333	1.84910714285714	0.155717231298298	0.472094792095022
GO:0004197	cysteine-type endopeptidase activity	20/3360	88/18639	0.227272727272727	1.26075487012987	0.155879986114259	0.472094792095022
GO:0004722	protein serine/threonine phosphatase activity	23/3360	103/18639	0.223300970873786	1.23872226074896	0.155924373951596	0.472094792095022
GO:0043014	alpha-tubulin binding	11/3360	44/18639	0.25	1.38683035714286	0.15616823921014	0.472094792095022
GO:0032452	histone demethylase activity	8/3360	30/18639	0.266666666666667	1.47928571428571	0.159012337167755	0.476312581721178
GO:0043995	histone H4K5 acetyltransferase activity	8/3360	30/18639	0.266666666666667	1.47928571428571	0.159012337167755	0.476312581721178
GO:0043996	histone H4K8 acetyltransferase activity	8/3360	30/18639	0.266666666666667	1.47928571428571	0.159012337167755	0.476312581721178
GO:0043997	histone H4K12 acetyltransferase activity	8/3360	30/18639	0.266666666666667	1.47928571428571	0.159012337167755	0.476312581721178
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	96/3360	484/18639	0.198347107438017	1.10029515938607	0.161330265461933	0.482157497914641
GO:0001846	opsonin binding	6/3360	21/18639	0.285714285714286	1.58494897959184	0.163189770393168	0.484302156385516
GO:0010314	phosphatidylinositol-5-phosphate binding	6/3360	21/18639	0.285714285714286	1.58494897959184	0.163189770393168	0.484302156385516
GO:0070182	DNA polymerase binding	6/3360	21/18639	0.285714285714286	1.58494897959184	0.163189770393168	0.484302156385516
GO:0004721	phosphoprotein phosphatase activity	37/3360	175/18639	0.211428571428571	1.17286224489796	0.163521032270091	0.484302156385516
GO:0016410	N-acyltransferase activity	21/3360	94/18639	0.223404255319149	1.23929521276596	0.168623862322315	0.498292986413134
GO:0030331	nuclear estrogen receptor binding	10/3360	40/18639	0.25	1.38683035714286	0.171159884604631	0.502400107712253
GO:0032451	demethylase activity	10/3360	40/18639	0.25	1.38683035714286	0.171159884604631	0.502400107712253
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	10/3360	40/18639	0.25	1.38683035714286	0.171159884604631	0.502400107712253
GO:0005112	Notch binding	7/3360	26/18639	0.269230769230769	1.49350961538462	0.174563544116037	0.508982395815053
GO:0034237	protein kinase A regulatory subunit binding	7/3360	26/18639	0.269230769230769	1.49350961538462	0.174563544116037	0.508982395815053
GO:0070006	metalloaminopeptidase activity	7/3360	26/18639	0.269230769230769	1.49350961538462	0.174563544116037	0.508982395815053
GO:0004715	non-membrane spanning protein tyrosine kinase activity	11/3360	45/18639	0.244444444444444	1.3560119047619	0.17498849992233	0.509092649110317
GO:0015399	primary active transmembrane transporter activity	35/3360	166/18639	0.210843373493976	1.16961596385542	0.17582581199188	0.51039943216186
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	5/3360	17/18639	0.294117647058824	1.63156512605042	0.178260282698081	0.511817187222656
GO:0005092	GDP-dissociation inhibitor activity	5/3360	17/18639	0.294117647058824	1.63156512605042	0.178260282698081	0.511817187222656
GO:0016805	dipeptidase activity	5/3360	17/18639	0.294117647058824	1.63156512605042	0.178260282698081	0.511817187222656
GO:0032977	membrane insertase activity	5/3360	17/18639	0.294117647058824	1.63156512605042	0.178260282698081	0.511817187222656
GO:1901567	fatty acid derivative binding	5/3360	17/18639	0.294117647058824	1.63156512605042	0.178260282698081	0.511817187222656
GO:0005164	tumor necrosis factor receptor binding	8/3360	31/18639	0.258064516129032	1.4315668202765	0.182484642714364	0.521352233277251
GO:0140457	protein demethylase activity	8/3360	31/18639	0.258064516129032	1.4315668202765	0.182484642714364	0.521352233277251
GO:0097110	scaffold protein binding	16/3360	70/18639	0.228571428571429	1.26795918367347	0.182770630829516	0.521352233277251
GO:0004407	histone deacetylase activity	6/3360	22/18639	0.272727272727273	1.51290584415584	0.192218815434485	0.540503077025193
GO:0033558	protein lysine deacetylase activity	6/3360	22/18639	0.272727272727273	1.51290584415584	0.192218815434485	0.540503077025193
GO:0008013	beta-catenin binding	23/3360	106/18639	0.216981132075472	1.20366408355795	0.193017427723463	0.540503077025193
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	4/3360	13/18639	0.307692307692308	1.70686813186813	0.194546466071746	0.540503077025193
GO:0009982	pseudouridine synthase activity	4/3360	13/18639	0.307692307692308	1.70686813186813	0.194546466071746	0.540503077025193
GO:0017154	semaphorin receptor activity	4/3360	13/18639	0.307692307692308	1.70686813186813	0.194546466071746	0.540503077025193
GO:0031994	insulin-like growth factor I binding	4/3360	13/18639	0.307692307692308	1.70686813186813	0.194546466071746	0.540503077025193
GO:0035673	oligopeptide transmembrane transporter activity	4/3360	13/18639	0.307692307692308	1.70686813186813	0.194546466071746	0.540503077025193
GO:0046974	histone H3K9 methyltransferase activity	4/3360	13/18639	0.307692307692308	1.70686813186813	0.194546466071746	0.540503077025193
GO:0046975	histone H3K36 methyltransferase activity	4/3360	13/18639	0.307692307692308	1.70686813186813	0.194546466071746	0.540503077025193
GO:0051011	microtubule minus-end binding	4/3360	13/18639	0.307692307692308	1.70686813186813	0.194546466071746	0.540503077025193
GO:0140410	monoatomic cation:bicarbonate symporter activity	4/3360	13/18639	0.307692307692308	1.70686813186813	0.194546466071746	0.540503077025193
GO:0030291	protein serine/threonine kinase inhibitor activity	11/3360	46/18639	0.239130434782609	1.32653338509317	0.194827725102617	0.540503077025193
GO:0050660	flavin adenine dinucleotide binding	19/3360	86/18639	0.22093023255814	1.22557101328904	0.197181479913785	0.545881360182373
GO:0001618	virus receptor activity	18/3360	81/18639	0.222222222222222	1.2327380952381	0.197914231756585	0.546758854537623
GO:0004364	glutathione transferase activity	7/3360	27/18639	0.259259259259259	1.43819444444444	0.201299045442397	0.5539033736659
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	26/3360	122/18639	0.213114754098361	1.18221604215457	0.201342823279316	0.5539033736659
GO:0001216	DNA-binding transcription activator activity	96/3360	491/18639	0.195519348268839	1.08460867035205	0.201783473775531	0.553956718193785
GO:0015631	tubulin binding	76/3360	385/18639	0.197402597402597	1.09505565862709	0.205695282827051	0.563519368578274
GO:0019888	protein phosphatase regulator activity	23/3360	107/18639	0.214953271028037	1.19241488651535	0.206292738535734	0.563981187472952
GO:0019213	deacetylase activity	9/3360	37/18639	0.243243243243243	1.34934845559846	0.211368404071697	0.57249587234254
GO:0008409	5'-3' exonuclease activity	5/3360	18/18639	0.277777777777778	1.54092261904762	0.212454741979589	0.57249587234254
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	5/3360	18/18639	0.277777777777778	1.54092261904762	0.212454741979589	0.57249587234254
GO:0016854	racemase and epimerase activity	5/3360	18/18639	0.277777777777778	1.54092261904762	0.212454741979589	0.57249587234254
GO:0017128	phospholipid scramblase activity	5/3360	18/18639	0.277777777777778	1.54092261904762	0.212454741979589	0.57249587234254
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	5/3360	18/18639	0.277777777777778	1.54092261904762	0.212454741979589	0.57249587234254
GO:0070064	proline-rich region binding	5/3360	18/18639	0.277777777777778	1.54092261904762	0.212454741979589	0.57249587234254
GO:0140272	exogenous protein binding	18/3360	82/18639	0.219512195121951	1.21770470383275	0.213422244806705	0.573926895543594
GO:0004402	histone acetyltransferase activity	10/3360	42/18639	0.238095238095238	1.32079081632653	0.213994300894282	0.574290827910166
GO:0005518	collagen binding	16/3360	72/18639	0.222222222222222	1.2327380952381	0.215472860384821	0.576279353854796
GO:0061733	protein-lysine-acetyltransferase activity	11/3360	47/18639	0.234042553191489	1.29830927051672	0.215611743039209	0.576279353854796
GO:0070851	growth factor receptor binding	29/3360	139/18639	0.20863309352518	1.15735483042138	0.219961523070618	0.586712784660979
GO:0000295	adenine nucleotide transmembrane transporter activity	6/3360	23/18639	0.260869565217391	1.44712732919255	0.22301782240864	0.592461487812852
GO:0004022	alcohol dehydrogenase (NAD+) activity	6/3360	23/18639	0.260869565217391	1.44712732919255	0.22301782240864	0.592461487812852
GO:0051213	dioxygenase activity	20/3360	93/18639	0.21505376344086	1.19297235023041	0.225824767241164	0.597504162821188
GO:0051219	phosphoprotein binding	20/3360	93/18639	0.21505376344086	1.19297235023041	0.225824767241164	0.597504162821188
GO:0016651	oxidoreductase activity, acting on NAD(P)H	19/3360	88/18639	0.215909090909091	1.19771712662338	0.227678544734785	0.601199370133015
GO:0036408	histone H3K14 acetyltransferase activity	7/3360	28/18639	0.25	1.38683035714286	0.22948065740281	0.60353412896939
GO:0051959	dynein light intermediate chain binding	7/3360	28/18639	0.25	1.38683035714286	0.22948065740281	0.60353412896939
GO:0019239	deaminase activity	8/3360	33/18639	0.242424242424242	1.34480519480519	0.233426685471707	0.611184487889696
GO:0005347	ATP transmembrane transporter activity	4/3360	14/18639	0.285714285714286	1.58494897959184	0.235929432864815	0.611184487889696
GO:0008191	metalloendopeptidase inhibitor activity	4/3360	14/18639	0.285714285714286	1.58494897959184	0.235929432864815	0.611184487889696
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	4/3360	14/18639	0.285714285714286	1.58494897959184	0.235929432864815	0.611184487889696
GO:0032454	histone H3K9 demethylase activity	4/3360	14/18639	0.285714285714286	1.58494897959184	0.235929432864815	0.611184487889696
GO:0061665	SUMO ligase activity	4/3360	14/18639	0.285714285714286	1.58494897959184	0.235929432864815	0.611184487889696
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	10/3360	43/18639	0.232558139534884	1.29007475083056	0.236892346605441	0.611184487889696
GO:0048156	tau protein binding	10/3360	43/18639	0.232558139534884	1.29007475083056	0.236892346605441	0.611184487889696
GO:0051018	protein kinase A binding	12/3360	53/18639	0.226415094339623	1.25599730458221	0.237037329903988	0.611184487889696
GO:1901505	carbohydrate derivative transmembrane transporter activity	12/3360	53/18639	0.226415094339623	1.25599730458221	0.237037329903988	0.611184487889696
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	27/3360	130/18639	0.207692307692308	1.15213598901099	0.237613549040028	0.611471266120621
GO:0005346	purine ribonucleotide transmembrane transporter activity	5/3360	19/18639	0.263157894736842	1.45982142857143	0.248497869466401	0.636987716078592
GO:0120227	acyl-CoA binding	5/3360	19/18639	0.263157894736842	1.45982142857143	0.248497869466401	0.636987716078592
GO:0060229	lipase activator activity	6/3360	24/18639	0.25	1.38683035714286	0.255281741803277	0.642980579849012
GO:0036002	pre-mRNA binding	13/3360	59/18639	0.220338983050847	1.2222911622276	0.256634473054788	0.642980579849012
GO:0010484	histone H3 acetyltransferase activity	7/3360	29/18639	0.241379310344828	1.33900862068966	0.258886192223798	0.642980579849012
GO:0106222	lncRNA binding	7/3360	29/18639	0.241379310344828	1.33900862068966	0.258886192223798	0.642980579849012
GO:0030332	cyclin binding	8/3360	34/18639	0.235294117647059	1.30525210084034	0.260570090425341	0.642980579849012
GO:0052866	phosphatidylinositol phosphate phosphatase activity	8/3360	34/18639	0.235294117647059	1.30525210084034	0.260570090425341	0.642980579849012
GO:0000182	rDNA binding	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0001094	TFIID-class transcription factor complex binding	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0005522	profilin binding	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0030957	Tat protein binding	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0042975	peroxisome proliferator activated receptor binding	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0047429	nucleoside triphosphate diphosphatase activity	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0050815	phosphoserine residue binding	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0051880	G-quadruplex DNA binding	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0097177	mitochondrial ribosome binding	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0099122	RNA polymerase II C-terminal domain binding	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:1990757	ubiquitin ligase activator activity	3/3360	10/18639	0.3	1.66419642857143	0.263548693945717	0.642980579849012
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	27/3360	132/18639	0.204545454545455	1.13467938311688	0.264573988254868	0.644286656583613
GO:0000149	SNARE binding	22/3360	106/18639	0.207547169811321	1.15133086253369	0.266723639611963	0.648320861533699
GO:0004519	endonuclease activity	26/3360	127/18639	0.204724409448819	1.13567210348706	0.267972322134339	0.650154250196783
GO:0098531	ligand-modulated transcription factor activity	13/3360	60/18639	0.216666666666667	1.20191964285714	0.27747785684752	0.670982486503283
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/3360	15/18639	0.266666666666667	1.47928571428571	0.279108304271708	0.670982486503283
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/3360	15/18639	0.266666666666667	1.47928571428571	0.279108304271708	0.670982486503283
GO:0015929	hexosaminidase activity	4/3360	15/18639	0.266666666666667	1.47928571428571	0.279108304271708	0.670982486503283
GO:0050700	CARD domain binding	4/3360	15/18639	0.266666666666667	1.47928571428571	0.279108304271708	0.670982486503283
GO:0010851	cyclase regulator activity	5/3360	20/18639	0.25	1.38683035714286	0.285926328043693	0.684869073547279
GO:0015095	magnesium ion transmembrane transporter activity	5/3360	20/18639	0.25	1.38683035714286	0.285926328043693	0.684869073547279
GO:0004177	aminopeptidase activity	9/3360	40/18639	0.225	1.24814732142857	0.287106000993008	0.685255389530041
GO:0001848	complement binding	6/3360	25/18639	0.24	1.33135714285714	0.288693145094785	0.685255389530041
GO:0004709	MAP kinase kinase kinase activity	6/3360	25/18639	0.24	1.33135714285714	0.288693145094785	0.685255389530041
GO:0042974	nuclear retinoic acid receptor binding	6/3360	25/18639	0.24	1.33135714285714	0.288693145094785	0.685255389530041
GO:0047617	fatty acyl-CoA hydrolase activity	6/3360	25/18639	0.24	1.33135714285714	0.288693145094785	0.685255389530041
GO:0140299	molecular sensor activity	15/3360	71/18639	0.211267605633803	1.17196931589537	0.29132833293961	0.690264428496553
GO:0030170	pyridoxal phosphate binding	12/3360	56/18639	0.214285714285714	1.18871173469388	0.302633871211082	0.715761763745635
GO:0015175	neutral L-amino acid transmembrane transporter activity	9/3360	41/18639	0.219512195121951	1.21770470383275	0.313840498553714	0.725221386967636
GO:0140828	metal cation:monoatomic cation antiporter activity	9/3360	41/18639	0.219512195121951	1.21770470383275	0.313840498553714	0.725221386967636
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/3360	11/18639	0.272727272727273	1.51290584415584	0.317306184856163	0.725221386967636
GO:0003953	NAD+ nucleosidase activity	3/3360	11/18639	0.272727272727273	1.51290584415584	0.317306184856163	0.725221386967636
GO:0008526	phosphatidylinositol transfer activity	3/3360	11/18639	0.272727272727273	1.51290584415584	0.317306184856163	0.725221386967636
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	3/3360	11/18639	0.272727272727273	1.51290584415584	0.317306184856163	0.725221386967636
GO:0015173	aromatic amino acid transmembrane transporter activity	3/3360	11/18639	0.272727272727273	1.51290584415584	0.317306184856163	0.725221386967636
GO:0015217	ADP transmembrane transporter activity	3/3360	11/18639	0.272727272727273	1.51290584415584	0.317306184856163	0.725221386967636
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	3/3360	11/18639	0.272727272727273	1.51290584415584	0.317306184856163	0.725221386967636
GO:0019107	myristoyltransferase activity	3/3360	11/18639	0.272727272727273	1.51290584415584	0.317306184856163	0.725221386967636
GO:0019206	nucleoside kinase activity	3/3360	11/18639	0.272727272727273	1.51290584415584	0.317306184856163	0.725221386967636
GO:0019215	intermediate filament binding	3/3360	11/18639	0.272727272727273	1.51290584415584	0.317306184856163	0.725221386967636
GO:0043522	leucine zipper domain binding	3/3360	11/18639	0.272727272727273	1.51290584415584	0.317306184856163	0.725221386967636
GO:0047676	arachidonate-CoA ligase activity	3/3360	11/18639	0.272727272727273	1.51290584415584	0.317306184856163	0.725221386967636
GO:0008327	methyl-CpG binding	7/3360	31/18639	0.225806451612903	1.25262096774194	0.320431982111806	0.725221386967636
GO:0004112	cyclic-nucleotide phosphodiesterase activity	6/3360	26/18639	0.230769230769231	1.2801510989011	0.32293202538841	0.725221386967636
GO:0004529	DNA exonuclease activity	6/3360	26/18639	0.230769230769231	1.2801510989011	0.32293202538841	0.725221386967636
GO:0008198	ferrous iron binding	6/3360	26/18639	0.230769230769231	1.2801510989011	0.32293202538841	0.725221386967636
GO:0016289	acyl-CoA hydrolase activity	6/3360	26/18639	0.230769230769231	1.2801510989011	0.32293202538841	0.725221386967636
GO:0050681	nuclear androgen receptor binding	6/3360	26/18639	0.230769230769231	1.2801510989011	0.32293202538841	0.725221386967636
GO:0051139	metal cation:proton antiporter activity	6/3360	26/18639	0.230769230769231	1.2801510989011	0.32293202538841	0.725221386967636
GO:0052742	phosphatidylinositol kinase activity	6/3360	26/18639	0.230769230769231	1.2801510989011	0.32293202538841	0.725221386967636
GO:0004707	MAP kinase activity	4/3360	16/18639	0.25	1.38683035714286	0.323355982579297	0.725221386967636
GO:0005149	interleukin-1 receptor binding	4/3360	16/18639	0.25	1.38683035714286	0.323355982579297	0.725221386967636
GO:0008296	3'-5'-DNA exonuclease activity	4/3360	16/18639	0.25	1.38683035714286	0.323355982579297	0.725221386967636
GO:0015385	sodium:proton antiporter activity	4/3360	16/18639	0.25	1.38683035714286	0.323355982579297	0.725221386967636
GO:0022858	alanine transmembrane transporter activity	4/3360	16/18639	0.25	1.38683035714286	0.323355982579297	0.725221386967636
GO:0055102	lipase inhibitor activity	4/3360	16/18639	0.25	1.38683035714286	0.323355982579297	0.725221386967636
GO:0097027	ubiquitin-protein transferase activator activity	4/3360	16/18639	0.25	1.38683035714286	0.323355982579297	0.725221386967636
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	4/3360	16/18639	0.25	1.38683035714286	0.323355982579297	0.725221386967636
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	5/3360	21/18639	0.238095238095238	1.32079081632653	0.324281502309483	0.725221386967636
GO:1904047	S-adenosyl-L-methionine binding	5/3360	21/18639	0.238095238095238	1.32079081632653	0.324281502309483	0.725221386967636
GO:0016504	peptidase activator activity	12/3360	57/18639	0.210526315789474	1.16785714285714	0.32552528976336	0.72553517972681
GO:0070279	vitamin B6 binding	12/3360	57/18639	0.210526315789474	1.16785714285714	0.32552528976336	0.72553517972681
GO:0042277	peptide binding	48/3360	249/18639	0.192771084337349	1.06936316695353	0.32722193078054	0.728082637861946
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	11/3360	52/18639	0.211538461538462	1.17347184065934	0.330558682804878	0.734264641703403
GO:0032934	sterol binding	14/3360	68/18639	0.205882352941176	1.14209558823529	0.337086376319288	0.747501829443277
GO:0019894	kinesin binding	9/3360	42/18639	0.214285714285714	1.18871173469388	0.34107127973356	0.755065206817561
GO:0005507	copper ion binding	13/3360	63/18639	0.206349206349206	1.14468537414966	0.342802077161489	0.756350220582815
GO:1901682	sulfur compound transmembrane transporter activity	13/3360	63/18639	0.206349206349206	1.14468537414966	0.342802077161489	0.756350220582815
GO:0016405	CoA-ligase activity	6/3360	27/18639	0.222222222222222	1.2327380952381	0.357684305372985	0.780834284627624
GO:0023026	MHC class II protein complex binding	6/3360	27/18639	0.222222222222222	1.2327380952381	0.357684305372985	0.780834284627624
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	6/3360	27/18639	0.222222222222222	1.2327380952381	0.357684305372985	0.780834284627624
GO:0032266	phosphatidylinositol-3-phosphate binding	10/3360	48/18639	0.208333333333333	1.15569196428571	0.361658618666423	0.780834284627624
GO:0008093	cytoskeletal anchor activity	5/3360	22/18639	0.227272727272727	1.26075487012987	0.363123469037423	0.780834284627624
GO:0008649	rRNA methyltransferase activity	5/3360	22/18639	0.227272727272727	1.26075487012987	0.363123469037423	0.780834284627624
GO:0031683	G-protein beta/gamma-subunit complex binding	5/3360	22/18639	0.227272727272727	1.26075487012987	0.363123469037423	0.780834284627624
GO:0004536	DNA nuclease activity	13/3360	64/18639	0.203125	1.12679966517857	0.365246663946767	0.780834284627624
GO:0008484	sulfuric ester hydrolase activity	4/3360	17/18639	0.235294117647059	1.30525210084034	0.368000813311981	0.780834284627624
GO:0008569	minus-end-directed microtubule motor activity	4/3360	17/18639	0.235294117647059	1.30525210084034	0.368000813311981	0.780834284627624
GO:0032183	SUMO binding	4/3360	17/18639	0.235294117647059	1.30525210084034	0.368000813311981	0.780834284627624
GO:0046965	nuclear retinoid X receptor binding	4/3360	17/18639	0.235294117647059	1.30525210084034	0.368000813311981	0.780834284627624
GO:0070402	NADPH binding	4/3360	17/18639	0.235294117647059	1.30525210084034	0.368000813311981	0.780834284627624
GO:0070403	NAD+ binding	4/3360	17/18639	0.235294117647059	1.30525210084034	0.368000813311981	0.780834284627624
GO:0008375	acetylglucosaminyltransferase activity	9/3360	43/18639	0.209302325581395	1.16106727574751	0.368648056149826	0.780834284627624
GO:0003995	acyl-CoA dehydrogenase activity	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:0004859	phospholipase inhibitor activity	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:0016801	hydrolase activity, acting on ether bonds	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:0016803	ether hydrolase activity	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:0034452	dynactin binding	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:0035197	siRNA binding	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:0035497	cAMP response element binding	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:0042301	phosphate ion binding	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:0070008	serine-type exopeptidase activity	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:0070410	co-SMAD binding	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:0070679	inositol 1,4,5 trisphosphate binding	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:1990247	N6-methyladenosine-containing RNA reader activity	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:1990459	transferrin receptor binding	3/3360	12/18639	0.25	1.38683035714286	0.371169169375453	0.780834284627624
GO:0004879	nuclear receptor activity	12/3360	59/18639	0.203389830508475	1.12826876513317	0.372306537233095	0.780834284627624
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/3360	59/18639	0.203389830508475	1.12826876513317	0.372306537233095	0.780834284627624
GO:0008238	exopeptidase activity	20/3360	102/18639	0.196078431372549	1.08771008403361	0.37744675349951	0.790354268872382
GO:0035591	signaling adaptor activity	25/3360	129/18639	0.193798449612403	1.0750622923588	0.378933795801223	0.792206584226721
GO:0016829	lyase activity	38/3360	200/18639	0.19	1.05399107142857	0.387698136024343	0.809242934717478
GO:0016866	intramolecular transferase activity	6/3360	28/18639	0.214285714285714	1.18871173469388	0.392648936637579	0.8169831513899
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	6/3360	28/18639	0.214285714285714	1.18871173469388	0.392648936637579	0.8169831513899
GO:0019205	nucleobase-containing compound kinase activity	9/3360	44/18639	0.204545454545455	1.13467938311688	0.396422911154032	0.823496637132231
GO:0003887	DNA-directed DNA polymerase activity	5/3360	23/18639	0.217391304347826	1.20593944099379	0.402041704212085	0.823496637132231
GO:0004602	glutathione peroxidase activity	5/3360	23/18639	0.217391304347826	1.20593944099379	0.402041704212085	0.823496637132231
GO:0008171	O-methyltransferase activity	5/3360	23/18639	0.217391304347826	1.20593944099379	0.402041704212085	0.823496637132231
GO:0016849	phosphorus-oxygen lyase activity	5/3360	23/18639	0.217391304347826	1.20593944099379	0.402041704212085	0.823496637132231
GO:0017134	fibroblast growth factor binding	5/3360	23/18639	0.217391304347826	1.20593944099379	0.402041704212085	0.823496637132231
GO:0042171	lysophosphatidic acid acyltransferase activity	5/3360	23/18639	0.217391304347826	1.20593944099379	0.402041704212085	0.823496637132231
GO:0044013	histone H2B acetyltransferase activity	5/3360	23/18639	0.217391304347826	1.20593944099379	0.402041704212085	0.823496637132231
GO:0071617	lysophospholipid acyltransferase activity	5/3360	23/18639	0.217391304347826	1.20593944099379	0.402041704212085	0.823496637132231
GO:0140102	catalytic activity, acting on a rRNA	5/3360	23/18639	0.217391304347826	1.20593944099379	0.402041704212085	0.823496637132231
GO:0004725	protein tyrosine phosphatase activity	19/3360	98/18639	0.193877551020408	1.07550109329446	0.402835217534926	0.823838741926014
GO:0008235	metalloexopeptidase activity	13/3360	66/18639	0.196969696969697	1.09265422077922	0.410662474267725	0.833121275870302
GO:0000900	mRNA regulatory element binding translation repressor activity	4/3360	18/18639	0.222222222222222	1.2327380952381	0.412442547978378	0.833121275870302
GO:0004706	JUN kinase kinase kinase activity	4/3360	18/18639	0.222222222222222	1.2327380952381	0.412442547978378	0.833121275870302
GO:0008308	voltage-gated monoatomic anion channel activity	4/3360	18/18639	0.222222222222222	1.2327380952381	0.412442547978378	0.833121275870302
GO:0008525	phosphatidylcholine transporter activity	4/3360	18/18639	0.222222222222222	1.2327380952381	0.412442547978378	0.833121275870302
GO:0031690	adrenergic receptor binding	4/3360	18/18639	0.222222222222222	1.2327380952381	0.412442547978378	0.833121275870302
GO:0098641	cadherin binding involved in cell-cell adhesion	4/3360	18/18639	0.222222222222222	1.2327380952381	0.412442547978378	0.833121275870302
GO:1901611	phosphatidylglycerol binding	4/3360	18/18639	0.222222222222222	1.2327380952381	0.412442547978378	0.833121275870302
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	7/3360	34/18639	0.205882352941176	1.14209558823529	0.416059636500878	0.839138684047015
GO:0003735	structural constituent of ribosome	33/3360	175/18639	0.188571428571429	1.04606632653061	0.41753775609536	0.840830243898008
GO:0015026	coreceptor activity	12/3360	61/18639	0.19672131147541	1.09127634660422	0.419811735237111	0.844011897433298
GO:0005035	death receptor activity	3/3360	13/18639	0.230769230769231	1.2801510989011	0.424155980366564	0.844011897433298
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/3360	13/18639	0.230769230769231	1.2801510989011	0.424155980366564	0.844011897433298
GO:0008253	5'-nucleotidase activity	3/3360	13/18639	0.230769230769231	1.2801510989011	0.424155980366564	0.844011897433298
GO:0043560	insulin receptor substrate binding	3/3360	13/18639	0.230769230769231	1.2801510989011	0.424155980366564	0.844011897433298
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/3360	13/18639	0.230769230769231	1.2801510989011	0.424155980366564	0.844011897433298
GO:0071837	HMG box domain binding	3/3360	13/18639	0.230769230769231	1.2801510989011	0.424155980366564	0.844011897433298
GO:0140303	intramembrane lipid transporter activity	9/3360	45/18639	0.2	1.10946428571429	0.424252368215521	0.844011897433298
GO:0050840	extracellular matrix binding	13/3360	67/18639	0.194029850746269	1.07634594882729	0.433476536733488	0.861059887922262
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	17/3360	89/18639	0.191011235955056	1.0596007223114	0.438473067056174	0.863593907959595
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	17/3360	89/18639	0.191011235955056	1.0596007223114	0.438473067056174	0.863593907959595
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	5/3360	24/18639	0.208333333333333	1.15569196428571	0.440662746951246	0.863593907959595
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	5/3360	24/18639	0.208333333333333	1.15569196428571	0.440662746951246	0.863593907959595
GO:0004622	lysophospholipase activity	5/3360	24/18639	0.208333333333333	1.15569196428571	0.440662746951246	0.863593907959595
GO:0005540	hyaluronic acid binding	5/3360	24/18639	0.208333333333333	1.15569196428571	0.440662746951246	0.863593907959595
GO:0015295	solute:proton symporter activity	5/3360	24/18639	0.208333333333333	1.15569196428571	0.440662746951246	0.863593907959595
GO:0043998	histone H2A acetyltransferase activity	5/3360	24/18639	0.208333333333333	1.15569196428571	0.440662746951246	0.863593907959595
GO:0050699	WW domain binding	5/3360	24/18639	0.208333333333333	1.15569196428571	0.440662746951246	0.863593907959595
GO:0004521	RNA endonuclease activity	14/3360	73/18639	0.191780821917808	1.0638698630137	0.445953577574508	0.872662134688211
GO:0005154	epidermal growth factor receptor binding	7/3360	35/18639	0.2	1.10946428571429	0.447926427104802	0.873921738342455
GO:0034061	DNA polymerase activity	7/3360	35/18639	0.2	1.10946428571429	0.447926427104802	0.873921738342455
GO:0005178	integrin binding	30/3360	161/18639	0.186335403726708	1.03366237799468	0.452407649027217	0.877165877499474
GO:0004601	peroxidase activity	11/3360	57/18639	0.192982456140351	1.07053571428571	0.454554647020215	0.877165877499474
GO:0008301	DNA binding, bending	4/3360	19/18639	0.210526315789474	1.16785714285714	0.456161128914905	0.877165877499474
GO:0042577	lipid phosphatase activity	4/3360	19/18639	0.210526315789474	1.16785714285714	0.456161128914905	0.877165877499474
GO:0042800	histone H3K4 methyltransferase activity	4/3360	19/18639	0.210526315789474	1.16785714285714	0.456161128914905	0.877165877499474
GO:0046624	sphingolipid transporter activity	4/3360	19/18639	0.210526315789474	1.16785714285714	0.456161128914905	0.877165877499474
GO:0050145	nucleoside monophosphate kinase activity	4/3360	19/18639	0.210526315789474	1.16785714285714	0.456161128914905	0.877165877499474
GO:0070003	threonine-type peptidase activity	4/3360	19/18639	0.210526315789474	1.16785714285714	0.456161128914905	0.877165877499474
GO:0097001	ceramide binding	4/3360	19/18639	0.210526315789474	1.16785714285714	0.456161128914905	0.877165877499474
GO:0005548	phospholipid transporter activity	13/3360	68/18639	0.191176470588235	1.06051733193277	0.456259665558662	0.877165877499474
GO:0140793	histone H2AXY142 phosphatase activity	17/3360	90/18639	0.188888888888889	1.04782738095238	0.458263736123768	0.879732573726649
GO:0016769	transferase activity, transferring nitrogenous groups	6/3360	30/18639	0.2	1.10946428571429	0.462108811295602	0.883175093951309
GO:0051721	protein phosphatase 2A binding	6/3360	30/18639	0.2	1.10946428571429	0.462108811295602	0.883175093951309
GO:0001727	lipid kinase activity	8/3360	41/18639	0.195121951219512	1.08240418118467	0.464925841150004	0.883175093951309
GO:0004065	arylsulfatase activity	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0004705	JUN kinase activity	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0005313	L-glutamate transmembrane transporter activity	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0005545	1-phosphatidylinositol binding	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0008195	phosphatidate phosphatase activity	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0008331	high voltage-gated calcium channel activity	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0016530	metallochaperone activity	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0019992	diacylglycerol binding	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0042043	neurexin family protein binding	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0042813	Wnt receptor activity	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0043176	amine binding	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0046030	inositol trisphosphate phosphatase activity	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0070742	C2H2 zinc finger domain binding	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0071933	Arp2/3 complex binding	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:1901612	cardiolipin binding	3/3360	14/18639	0.214285714285714	1.18871173469388	0.475490493321588	0.883175093951309
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	17/3360	91/18639	0.186813186813187	1.03631279434851	0.477995492804585	0.883175093951309
GO:0000030	mannosyltransferase activity	5/3360	25/18639	0.2	1.10946428571429	0.47865514741536	0.883175093951309
GO:0008483	transaminase activity	5/3360	25/18639	0.2	1.10946428571429	0.47865514741536	0.883175093951309
GO:0015645	fatty acid ligase activity	5/3360	25/18639	0.2	1.10946428571429	0.47865514741536	0.883175093951309
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	5/3360	25/18639	0.2	1.10946428571429	0.47865514741536	0.883175093951309
GO:0120515	fatty acid-CoA ligase activity	5/3360	25/18639	0.2	1.10946428571429	0.47865514741536	0.883175093951309
GO:0004033	aldo-keto reductase (NADPH) activity	7/3360	36/18639	0.194444444444444	1.07864583333333	0.479454713239997	0.883175093951309
GO:0005484	SNAP receptor activity	7/3360	36/18639	0.194444444444444	1.07864583333333	0.479454713239997	0.883175093951309
GO:0055106	ubiquitin-protein transferase regulator activity	7/3360	36/18639	0.194444444444444	1.07864583333333	0.479454713239997	0.883175093951309
GO:0043495	protein-membrane adaptor activity	9/3360	47/18639	0.191489361702128	1.06225303951368	0.479533853293714	0.883175093951309
GO:0016209	antioxidant activity	16/3360	86/18639	0.186046511627907	1.03205980066445	0.488384533743932	0.898217708913665
GO:0016758	hexosyltransferase activity	36/3360	197/18639	0.182741116751269	1.01372371283539	0.493153201026332	0.905721311940819
GO:0031492	nucleosomal DNA binding	8/3360	42/18639	0.19047619047619	1.05663265306122	0.49406809089505	0.906136038391897
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	4/3360	20/18639	0.2	1.10946428571429	0.498719829132707	0.908326418890774
GO:0016505	peptidase activator activity involved in apoptotic process	4/3360	20/18639	0.2	1.10946428571429	0.498719829132707	0.908326418890774
GO:0030742	GTP-dependent protein binding	4/3360	20/18639	0.2	1.10946428571429	0.498719829132707	0.908326418890774
GO:0042288	MHC class I protein binding	4/3360	20/18639	0.2	1.10946428571429	0.498719829132707	0.908326418890774
GO:0052745	inositol phosphate phosphatase activity	4/3360	20/18639	0.2	1.10946428571429	0.498719829132707	0.908326418890774
GO:0030971	receptor tyrosine kinase binding	15/3360	81/18639	0.185185185185185	1.02728174603175	0.499406844758958	0.908326418890774
GO:0045309	protein phosphorylated amino acid binding	11/3360	59/18639	0.186440677966102	1.03424636803874	0.503832133050055	0.915109468177931
GO:0042626	ATPase-coupled transmembrane transporter activity	18/3360	98/18639	0.183673469387755	1.01889577259475	0.506287081456569	0.918300016710881
GO:0008081	phosphoric diester hydrolase activity	16/3360	87/18639	0.183908045977011	1.02019704433498	0.508547941881256	0.921130225308335
GO:0023023	MHC protein complex binding	7/3360	37/18639	0.189189189189189	1.04949324324324	0.510469476249945	0.922233480438549
GO:0017124	SH3 domain binding	21/3360	115/18639	0.182608695652174	1.01298913043478	0.512108924946036	0.922233480438549
GO:0038024	cargo receptor activity	12/3360	65/18639	0.184615384615385	1.02412087912088	0.514212225532781	0.922233480438549
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/3360	26/18639	0.192307692307692	1.06679258241758	0.515732081231301	0.922233480438549
GO:0008157	protein phosphatase 1 binding	5/3360	26/18639	0.192307692307692	1.06679258241758	0.515732081231301	0.922233480438549
GO:0030247	polysaccharide binding	5/3360	26/18639	0.192307692307692	1.06679258241758	0.515732081231301	0.922233480438549
GO:0070412	R-SMAD binding	5/3360	26/18639	0.192307692307692	1.06679258241758	0.515732081231301	0.922233480438549
GO:0120014	phospholipid transfer activity	5/3360	26/18639	0.192307692307692	1.06679258241758	0.515732081231301	0.922233480438549
GO:0015485	cholesterol binding	10/3360	54/18639	0.185185185185185	1.02728174603175	0.517949654288141	0.922233480438549
GO:0050661	NADP binding	10/3360	54/18639	0.185185185185185	1.02728174603175	0.517949654288141	0.922233480438549
GO:0004175	endopeptidase activity	73/3360	405/18639	0.180246913580247	0.999887566137566	0.521174755266548	0.922233480438549
GO:0004467	long-chain fatty acid-CoA ligase activity	3/3360	15/18639	0.2	1.10946428571429	0.524586040584057	0.922233480438549
GO:0005041	low-density lipoprotein particle receptor activity	3/3360	15/18639	0.2	1.10946428571429	0.524586040584057	0.922233480438549
GO:0008252	nucleotidase activity	3/3360	15/18639	0.2	1.10946428571429	0.524586040584057	0.922233480438549
GO:0010181	FMN binding	3/3360	15/18639	0.2	1.10946428571429	0.524586040584057	0.922233480438549
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	3/3360	15/18639	0.2	1.10946428571429	0.524586040584057	0.922233480438549
GO:0031005	filamin binding	3/3360	15/18639	0.2	1.10946428571429	0.524586040584057	0.922233480438549
GO:0031386	protein tag activity	3/3360	15/18639	0.2	1.10946428571429	0.524586040584057	0.922233480438549
GO:0042809	nuclear vitamin D receptor binding	3/3360	15/18639	0.2	1.10946428571429	0.524586040584057	0.922233480438549
GO:0050780	dopamine receptor binding	3/3360	15/18639	0.2	1.10946428571429	0.524586040584057	0.922233480438549
GO:0120283	protein serine/threonine kinase binding	3/3360	15/18639	0.2	1.10946428571429	0.524586040584057	0.922233480438549
GO:0141047	molecular tag activity	3/3360	15/18639	0.2	1.10946428571429	0.524586040584057	0.922233480438549
GO:0004714	transmembrane receptor protein tyrosine kinase activity	11/3360	60/18639	0.183333333333333	1.01700892857143	0.528036269436304	0.925823592411652
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	11/3360	60/18639	0.183333333333333	1.01700892857143	0.528036269436304	0.925823592411652
GO:0035091	phosphatidylinositol binding	51/3360	284/18639	0.179577464788732	0.996173918511067	0.53675315604304	0.935108649798768
GO:0019842	vitamin binding	27/3360	150/18639	0.18	0.998517857142857	0.536997497825376	0.935108649798768
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	4/3360	21/18639	0.19047619047619	1.05663265306122	0.539764141326407	0.935108649798768
GO:0009975	cyclase activity	4/3360	21/18639	0.19047619047619	1.05663265306122	0.539764141326407	0.935108649798768
GO:0019200	carbohydrate kinase activity	4/3360	21/18639	0.19047619047619	1.05663265306122	0.539764141326407	0.935108649798768
GO:0051010	microtubule plus-end binding	4/3360	21/18639	0.19047619047619	1.05663265306122	0.539764141326407	0.935108649798768
GO:0140312	cargo adaptor activity	4/3360	21/18639	0.19047619047619	1.05663265306122	0.539764141326407	0.935108649798768
GO:0042162	telomeric DNA binding	7/3360	38/18639	0.184210526315789	1.021875	0.540814691440354	0.935108649798768
GO:0046982	protein heterodimerization activity	66/3360	369/18639	0.178861788617886	0.992203832752613	0.549939790595115	0.935108649798768
GO:0016790	thiolester hydrolase activity	8/3360	44/18639	0.181818181818182	1.0086038961039	0.550804997686957	0.935108649798768
GO:0004683	calcium/calmodulin-dependent protein kinase activity	5/3360	27/18639	0.185185185185185	1.02728174603175	0.551652030290009	0.935108649798768
GO:0005044	scavenger receptor activity	5/3360	27/18639	0.185185185185185	1.02728174603175	0.551652030290009	0.935108649798768
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	5/3360	27/18639	0.185185185185185	1.02728174603175	0.551652030290009	0.935108649798768
GO:0019905	syntaxin binding	11/3360	61/18639	0.180327868852459	1.00033665105386	0.551845666960126	0.935108649798768
GO:0015078	proton transmembrane transporter activity	33/3360	185/18639	0.178378378378378	0.989522200772201	0.557054656671825	0.935108649798768
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	12/3360	67/18639	0.17910447761194	0.993550106609808	0.559858934744581	0.935108649798768
GO:0051117	ATPase binding	15/3360	84/18639	0.178571428571429	0.990593112244898	0.560837315146082	0.935108649798768
GO:0019956	chemokine binding	6/3360	33/18639	0.181818181818182	1.0086038961039	0.561633717468365	0.935108649798768
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0004090	carbonyl reductase (NADPH) activity	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0005031	tumor necrosis factor receptor activity	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0005131	growth hormone receptor binding	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0015187	glycine transmembrane transporter activity	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0015279	store-operated calcium channel activity	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0016427	tRNA (cytidine) methyltransferase activity	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0031434	mitogen-activated protein kinase kinase binding	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0032052	bile acid binding	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0032356	oxidized DNA binding	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0035256	G protein-coupled glutamate receptor binding	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0050308	sugar-phosphatase activity	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0051378	serotonin binding	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0070097	delta-catenin binding	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0070513	death domain binding	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0140135	mechanosensitive monoatomic cation channel activity	2/3360	10/18639	0.2	1.10946428571429	0.561776299118652	0.935108649798768
GO:0022853	active monoatomic ion transmembrane transporter activity	21/3360	118/18639	0.177966101694915	0.987235169491525	0.563766650593954	0.937235329369216
GO:0005159	insulin-like growth factor receptor binding	3/3360	16/18639	0.1875	1.04012276785714	0.571023746277463	0.940010093376962
GO:0034450	ubiquitin-ubiquitin ligase activity	3/3360	16/18639	0.1875	1.04012276785714	0.571023746277463	0.940010093376962
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/3360	16/18639	0.1875	1.04012276785714	0.571023746277463	0.940010093376962
GO:0140327	flippase activity	3/3360	16/18639	0.1875	1.04012276785714	0.571023746277463	0.940010093376962
GO:0016835	carbon-oxygen lyase activity	14/3360	79/18639	0.177215189873418	0.983069620253164	0.574209135801074	0.940010093376962
GO:0016798	hydrolase activity, acting on glycosyl bonds	23/3360	130/18639	0.176923076923077	0.981449175824176	0.575602939710679	0.940010093376962
GO:0032931	histone H3K56 acetyltransferase activity	4/3360	22/18639	0.181818181818182	1.0086038961039	0.579017624057292	0.940010093376962
GO:0043992	histone H3K9 acetyltransferase activity	4/3360	22/18639	0.181818181818182	1.0086038961039	0.579017624057292	0.940010093376962
GO:0043993	histone H3K18 acetyltransferase activity	4/3360	22/18639	0.181818181818182	1.0086038961039	0.579017624057292	0.940010093376962
GO:0043994	histone H3K23 acetyltransferase activity	4/3360	22/18639	0.181818181818182	1.0086038961039	0.579017624057292	0.940010093376962
GO:0043999	histone H2AK5 acetyltransferase activity	4/3360	22/18639	0.181818181818182	1.0086038961039	0.579017624057292	0.940010093376962
GO:0044012	histone H2AK9 acetyltransferase activity	4/3360	22/18639	0.181818181818182	1.0086038961039	0.579017624057292	0.940010093376962
GO:0044014	histone H2BK5 acetyltransferase activity	4/3360	22/18639	0.181818181818182	1.0086038961039	0.579017624057292	0.940010093376962
GO:0044015	histone H2BK12 acetyltransferase activity	4/3360	22/18639	0.181818181818182	1.0086038961039	0.579017624057292	0.940010093376962
GO:0044016	histone H3K4 acetyltransferase activity	4/3360	22/18639	0.181818181818182	1.0086038961039	0.579017624057292	0.940010093376962
GO:0044017	histone H3K27 acetyltransferase activity	4/3360	22/18639	0.181818181818182	1.0086038961039	0.579017624057292	0.940010093376962
GO:0044018	histone H3K36 acetyltransferase activity	4/3360	22/18639	0.181818181818182	1.0086038961039	0.579017624057292	0.940010093376962
GO:0046972	histone H4K16 acetyltransferase activity	4/3360	22/18639	0.181818181818182	1.0086038961039	0.579017624057292	0.940010093376962
GO:0140908	histone H3K122 acetyltransferase activity	4/3360	22/18639	0.181818181818182	1.0086038961039	0.579017624057292	0.940010093376962
GO:0005021	vascular endothelial growth factor receptor activity	9/3360	51/18639	0.176470588235294	0.978939075630252	0.585292339412727	0.947856436364207
GO:0016597	amino acid binding	9/3360	51/18639	0.176470588235294	0.978939075630252	0.585292339412727	0.947856436364207
GO:0046625	sphingolipid binding	5/3360	28/18639	0.178571428571429	0.990593112244898	0.586217920214449	0.94818765692743
GO:0008376	acetylgalactosaminyltransferase activity	6/3360	34/18639	0.176470588235294	0.978939075630252	0.592828163389969	0.956791690514958
GO:0005506	iron ion binding	27/3360	154/18639	0.175324675324675	0.9725823283859	0.596615085777761	0.956791690514958
GO:0050997	quaternary ammonium group binding	7/3360	40/18639	0.175	0.97078125	0.598970905022795	0.956791690514958
GO:0043178	alcohol binding	16/3360	92/18639	0.173913043478261	0.964751552795031	0.605640869449605	0.956791690514958
GO:0052689	carboxylic ester hydrolase activity	16/3360	92/18639	0.173913043478261	0.964751552795031	0.605640869449605	0.956791690514958
GO:0004550	nucleoside diphosphate kinase activity	3/3360	17/18639	0.176470588235294	0.978939075630252	0.614528660484352	0.956791690514958
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/3360	17/18639	0.176470588235294	0.978939075630252	0.614528660484352	0.956791690514958
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/3360	17/18639	0.176470588235294	0.978939075630252	0.614528660484352	0.956791690514958
GO:0016018	cyclosporin A binding	3/3360	17/18639	0.176470588235294	0.978939075630252	0.614528660484352	0.956791690514958
GO:0019198	transmembrane receptor protein phosphatase activity	3/3360	17/18639	0.176470588235294	0.978939075630252	0.614528660484352	0.956791690514958
GO:0038191	neuropilin binding	3/3360	17/18639	0.176470588235294	0.978939075630252	0.614528660484352	0.956791690514958
GO:0045125	bioactive lipid receptor activity	3/3360	17/18639	0.176470588235294	0.978939075630252	0.614528660484352	0.956791690514958
GO:0070492	oligosaccharide binding	3/3360	17/18639	0.176470588235294	0.978939075630252	0.614528660484352	0.956791690514958
GO:0030246	carbohydrate binding	49/3360	280/18639	0.175	0.97078125	0.615812959949649	0.956791690514958
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0001851	complement component C3b binding	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0005225	volume-sensitive anion channel activity	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0008046	axon guidance receptor activity	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0008172	S-methyltransferase activity	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0019203	carbohydrate phosphatase activity	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0034056	estrogen response element binding	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0034713	type I transforming growth factor beta receptor binding	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0045294	alpha-catenin binding	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0070697	activin receptor binding	2/3360	11/18639	0.181818181818182	1.0086038961039	0.616102991176982	0.956791690514958
GO:0005158	insulin receptor binding	4/3360	23/18639	0.173913043478261	0.964751552795031	0.616275712445757	0.956791690514958
GO:0005212	structural constituent of eye lens	4/3360	23/18639	0.173913043478261	0.964751552795031	0.616275712445757	0.956791690514958
GO:0031681	G-protein beta-subunit binding	4/3360	23/18639	0.173913043478261	0.964751552795031	0.616275712445757	0.956791690514958
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/3360	23/18639	0.173913043478261	0.964751552795031	0.616275712445757	0.956791690514958
GO:0140103	catalytic activity, acting on a glycoprotein	4/3360	23/18639	0.173913043478261	0.964751552795031	0.616275712445757	0.956791690514958
GO:0004629	phospholipase C activity	5/3360	29/18639	0.172413793103448	0.956434729064039	0.61927507742265	0.95805497271857
GO:0016417	S-acyltransferase activity	5/3360	29/18639	0.172413793103448	0.956434729064039	0.61927507742265	0.95805497271857
GO:0051861	glycolipid binding	5/3360	29/18639	0.172413793103448	0.956434729064039	0.61927507742265	0.95805497271857
GO:0005516	calmodulin binding	36/3360	207/18639	0.173913043478261	0.964751552795031	0.622818802360142	0.962405082377893
GO:0005085	guanyl-nucleotide exchange factor activity	40/3360	230/18639	0.173913043478261	0.964751552795031	0.626426456472409	0.964797974118963
GO:0042169	SH2 domain binding	7/3360	41/18639	0.170731707317073	0.947103658536585	0.626568418173076	0.964797974118963
GO:0042287	MHC protein binding	7/3360	41/18639	0.170731707317073	0.947103658536585	0.626568418173076	0.964797974118963
GO:1901981	phosphatidylinositol phosphate binding	32/3360	185/18639	0.172972972972973	0.95953667953668	0.632171256800482	0.97228678677501
GO:0008106	alcohol dehydrogenase (NADP+) activity	5/3360	30/18639	0.166666666666667	0.924553571428571	0.650708330648059	0.992727614678244
GO:0031210	phosphatidylcholine binding	5/3360	30/18639	0.166666666666667	0.924553571428571	0.650708330648059	0.992727614678244
GO:0033612	receptor serine/threonine kinase binding	5/3360	30/18639	0.166666666666667	0.924553571428571	0.650708330648059	0.992727614678244
GO:0050431	transforming growth factor beta binding	4/3360	24/18639	0.166666666666667	0.924553571428571	0.651398305544659	0.992727614678244
GO:0004190	aspartic-type endopeptidase activity	6/3360	36/18639	0.166666666666667	0.924553571428571	0.651478456911454	0.992727614678244
GO:0004520	DNA endonuclease activity	7/3360	42/18639	0.166666666666667	0.924553571428571	0.653068483628681	0.992727614678244
GO:0030228	lipoprotein particle receptor activity	3/3360	18/18639	0.166666666666667	0.924553571428571	0.654945882985546	0.992727614678244
GO:0034185	apolipoprotein binding	3/3360	18/18639	0.166666666666667	0.924553571428571	0.654945882985546	0.992727614678244
GO:0035615	clathrin adaptor activity	3/3360	18/18639	0.166666666666667	0.924553571428571	0.654945882985546	0.992727614678244
GO:0003720	telomerase activity	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0004000	adenosine deaminase activity	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0004126	cytidine deaminase activity	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0005025	transforming growth factor beta receptor activity, type I	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0005026	transforming growth factor beta receptor activity, type II	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0005247	voltage-gated chloride channel activity	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0015368	calcium:monoatomic cation antiporter activity	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0016208	AMP binding	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0016361	activin receptor activity, type I	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0016362	activin receptor activity, type II	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0016840	carbon-nitrogen lyase activity	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0017002	activin receptor activity	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0043047	single-stranded telomeric DNA binding	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0097677	STAT family protein binding	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/3360	12/18639	0.166666666666667	0.924553571428571	0.665089755537287	0.992727614678244
GO:0019199	transmembrane receptor protein kinase activity	13/3360	78/18639	0.166666666666667	0.924553571428571	0.668274029482618	0.99634960177964
GO:0060589	nucleoside-triphosphatase regulator activity	85/3360	490/18639	0.173469387755102	0.962290451895044	0.672419319898897	1
GO:0005245	voltage-gated calcium channel activity	7/3360	43/18639	0.162790697674419	0.903052325581395	0.678411002893766	1
GO:0070001	aspartic-type peptidase activity	6/3360	37/18639	0.162162162162162	0.899565637065637	0.678770517684649	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	5/3360	31/18639	0.161290322580645	0.894729262672811	0.680438538407357	1
GO:0016836	hydro-lyase activity	10/3360	61/18639	0.163934426229508	0.909396955503513	0.681305381378081	1
GO:0005496	steroid binding	18/3360	108/18639	0.166666666666667	0.924553571428571	0.682119641370364	1
GO:0003707	nuclear steroid receptor activity	4/3360	25/18639	0.16	0.887571428571429	0.684301764235954	1
GO:0005537	D-mannose binding	4/3360	25/18639	0.16	0.887571428571429	0.684301764235954	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	4/3360	25/18639	0.16	0.887571428571429	0.684301764235954	1
GO:0019707	protein-cysteine S-acyltransferase activity	4/3360	25/18639	0.16	0.887571428571429	0.684301764235954	1
GO:0008017	microtubule binding	47/3360	276/18639	0.170289855072464	0.944652562111801	0.691839110699975	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	3/3360	19/18639	0.157894736842105	0.875892857142857	0.692218024373792	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/3360	19/18639	0.157894736842105	0.875892857142857	0.692218024373792	1
GO:0022821	solute:potassium antiporter activity	3/3360	19/18639	0.157894736842105	0.875892857142857	0.692218024373792	1
GO:0022840	leak channel activity	3/3360	19/18639	0.157894736842105	0.875892857142857	0.692218024373792	1
GO:0022842	narrow pore channel activity	3/3360	19/18639	0.157894736842105	0.875892857142857	0.692218024373792	1
GO:0043395	heparan sulfate proteoglycan binding	3/3360	19/18639	0.157894736842105	0.875892857142857	0.692218024373792	1
GO:0005017	platelet-derived growth factor receptor activity	8/3360	50/18639	0.16	0.887571428571429	0.701582066346884	1
GO:0005019	platelet-derived growth factor beta-receptor activity	8/3360	50/18639	0.16	0.887571428571429	0.701582066346884	1
GO:0015179	L-amino acid transmembrane transporter activity	10/3360	62/18639	0.161290322580645	0.894729262672811	0.7017121955913	1
GO:0005109	frizzled binding	6/3360	38/18639	0.157894736842105	0.875892857142857	0.704637235105455	1
GO:0030695	GTPase regulator activity	84/3360	489/18639	0.171779141104294	0.952914110429448	0.707457733315282	1
GO:0042910	xenobiotic transmembrane transporter activity	5/3360	32/18639	0.15625	0.866768973214286	0.7084187791392	1
GO:0002161	aminoacyl-tRNA editing activity	2/3360	13/18639	0.153846153846154	0.853434065934066	0.708895896477419	1
GO:0003964	RNA-directed DNA polymerase activity	2/3360	13/18639	0.153846153846154	0.853434065934066	0.708895896477419	1
GO:0004993	G protein-coupled serotonin receptor activity	2/3360	13/18639	0.153846153846154	0.853434065934066	0.708895896477419	1
GO:0005172	vascular endothelial growth factor receptor binding	2/3360	13/18639	0.153846153846154	0.853434065934066	0.708895896477419	1
GO:0008035	high-density lipoprotein particle binding	2/3360	13/18639	0.153846153846154	0.853434065934066	0.708895896477419	1
GO:0008417	fucosyltransferase activity	2/3360	13/18639	0.153846153846154	0.853434065934066	0.708895896477419	1
GO:0019104	DNA N-glycosylase activity	2/3360	13/18639	0.153846153846154	0.853434065934066	0.708895896477419	1
GO:0039706	co-receptor binding	2/3360	13/18639	0.153846153846154	0.853434065934066	0.708895896477419	1
GO:0045159	myosin II binding	2/3360	13/18639	0.153846153846154	0.853434065934066	0.708895896477419	1
GO:0070123	transforming growth factor beta receptor activity, type III	2/3360	13/18639	0.153846153846154	0.853434065934066	0.708895896477419	1
GO:0071714	icosanoid transmembrane transporter activity	2/3360	13/18639	0.153846153846154	0.853434065934066	0.708895896477419	1
GO:0089720	caspase binding	2/3360	13/18639	0.153846153846154	0.853434065934066	0.708895896477419	1
GO:0004435	phosphatidylinositol phospholipase C activity	4/3360	26/18639	0.153846153846154	0.853434065934066	0.714950797509527	1
GO:0005160	transforming growth factor beta receptor binding	4/3360	26/18639	0.153846153846154	0.853434065934066	0.714950797509527	1
GO:0005010	insulin-like growth factor receptor activity	8/3360	51/18639	0.156862745098039	0.870168067226891	0.723217364381146	1
GO:0022804	active transmembrane transporter activity	78/3360	457/18639	0.170678336980306	0.946807596123789	0.723556265024528	1
GO:1902936	phosphatidylinositol bisphosphate binding	18/3360	111/18639	0.162162162162162	0.899565637065637	0.727407377523127	1
GO:1990782	protein tyrosine kinase binding	19/3360	117/18639	0.162393162393162	0.90084706959707	0.728806338291874	1
GO:0003774	cytoskeletal motor activity	25/3360	153/18639	0.163398692810458	0.906425070028011	0.738110006858223	1
GO:0005104	fibroblast growth factor receptor binding	4/3360	27/18639	0.148148148148148	0.821825396825397	0.743350583112922	1
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/3360	27/18639	0.148148148148148	0.821825396825397	0.743350583112922	1
GO:0008474	palmitoyl-(protein) hydrolase activity	2/3360	14/18639	0.142857142857143	0.792474489795918	0.747796797003391	1
GO:0015386	potassium:proton antiporter activity	2/3360	14/18639	0.142857142857143	0.792474489795918	0.747796797003391	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/3360	14/18639	0.142857142857143	0.792474489795918	0.747796797003391	1
GO:0031404	chloride ion binding	2/3360	14/18639	0.142857142857143	0.792474489795918	0.747796797003391	1
GO:0034236	protein kinase A catalytic subunit binding	2/3360	14/18639	0.142857142857143	0.792474489795918	0.747796797003391	1
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/3360	14/18639	0.142857142857143	0.792474489795918	0.747796797003391	1
GO:0044548	S100 protein binding	2/3360	14/18639	0.142857142857143	0.792474489795918	0.747796797003391	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/3360	14/18639	0.142857142857143	0.792474489795918	0.747796797003391	1
GO:0098599	palmitoyl hydrolase activity	2/3360	14/18639	0.142857142857143	0.792474489795918	0.747796797003391	1
GO:0098821	BMP receptor activity	2/3360	14/18639	0.142857142857143	0.792474489795918	0.747796797003391	1
GO:0098847	sequence-specific single stranded DNA binding	2/3360	14/18639	0.142857142857143	0.792474489795918	0.747796797003391	1
GO:1901474	azole transmembrane transporter activity	2/3360	14/18639	0.142857142857143	0.792474489795918	0.747796797003391	1
GO:0005319	lipid transporter activity	29/3360	178/18639	0.162921348314607	0.903777086677368	0.755629736175961	1
GO:0004857	enzyme inhibitor activity	70/3360	416/18639	0.168269230769231	0.933443509615385	0.75856631880543	1
GO:0005246	calcium channel regulator activity	8/3360	53/18639	0.150943396226415	0.83733153638814	0.763241377565587	1
GO:0001784	phosphotyrosine residue binding	7/3360	47/18639	0.148936170212766	0.826196808510638	0.767563271468355	1
GO:0045499	chemorepellent activity	4/3360	28/18639	0.142857142857143	0.792474489795918	0.769539360262667	1
GO:0046875	ephrin receptor binding	4/3360	28/18639	0.142857142857143	0.792474489795918	0.769539360262667	1
GO:0051119	sugar transmembrane transporter activity	4/3360	28/18639	0.142857142857143	0.792474489795918	0.769539360262667	1
GO:0019955	cytokine binding	23/3360	144/18639	0.159722222222222	0.886030505952381	0.771135211694827	1
GO:0001530	lipopolysaccharide binding	6/3360	41/18639	0.146341463414634	0.811803135888502	0.773511834196732	1
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	6/3360	41/18639	0.146341463414634	0.811803135888502	0.773511834196732	1
GO:0016229	steroid dehydrogenase activity	5/3360	35/18639	0.142857142857143	0.792474489795918	0.781790929203856	1
GO:0004129	cytochrome-c oxidase activity	2/3360	15/18639	0.133333333333333	0.739642857142857	0.782136913375596	1
GO:0008242	omega peptidase activity	2/3360	15/18639	0.133333333333333	0.739642857142857	0.782136913375596	1
GO:0048531	beta-1,3-galactosyltransferase activity	2/3360	15/18639	0.133333333333333	0.739642857142857	0.782136913375596	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	2/3360	15/18639	0.133333333333333	0.739642857142857	0.782136913375596	1
GO:0008194	UDP-glycosyltransferase activity	23/3360	145/18639	0.158620689655172	0.879919950738916	0.782455849524207	1
GO:0008970	phospholipase A1 activity	3/3360	22/18639	0.136363636363636	0.756452922077922	0.785640749326295	1
GO:0016881	acid-amino acid ligase activity	3/3360	22/18639	0.136363636363636	0.756452922077922	0.785640749326295	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/3360	22/18639	0.136363636363636	0.756452922077922	0.785640749326295	1
GO:0061133	endopeptidase activator activity	3/3360	22/18639	0.136363636363636	0.756452922077922	0.785640749326295	1
GO:0008514	organic anion transmembrane transporter activity	44/3360	269/18639	0.163568773234201	0.907368560807223	0.785676407790719	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	29/3360	181/18639	0.160220994475138	0.888797355958958	0.786666253102182	1
GO:0031406	carboxylic acid binding	30/3360	187/18639	0.160427807486631	0.88994461420932	0.787530070390607	1
GO:0003785	actin monomer binding	4/3360	29/18639	0.137931034482759	0.765147783251231	0.79358164551707	1
GO:0033218	amide binding	40/3360	247/18639	0.161943319838057	0.898351648351648	0.797401600495083	1
GO:0016409	palmitoyltransferase activity	5/3360	36/18639	0.138888888888889	0.77046130952381	0.802809069896179	1
GO:0015297	antiporter activity	21/3360	135/18639	0.155555555555556	0.862916666666667	0.804024637114392	1
GO:0005004	GPI-linked ephrin receptor activity	7/3360	49/18639	0.142857142857143	0.792474489795918	0.804735528153221	1
GO:0005008	hepatocyte growth factor receptor activity	7/3360	49/18639	0.142857142857143	0.792474489795918	0.804735528153221	1
GO:0005009	insulin receptor activity	7/3360	49/18639	0.142857142857143	0.792474489795918	0.804735528153221	1
GO:0005011	macrophage colony-stimulating factor receptor activity	7/3360	49/18639	0.142857142857143	0.792474489795918	0.804735528153221	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	7/3360	49/18639	0.142857142857143	0.792474489795918	0.804735528153221	1
GO:0005020	stem cell factor receptor activity	7/3360	49/18639	0.142857142857143	0.792474489795918	0.804735528153221	1
GO:0008288	boss receptor activity	7/3360	49/18639	0.142857142857143	0.792474489795918	0.804735528153221	1
GO:0036332	placental growth factor receptor activity	7/3360	49/18639	0.142857142857143	0.792474489795918	0.804735528153221	1
GO:0038062	protein tyrosine kinase collagen receptor activity	7/3360	49/18639	0.142857142857143	0.792474489795918	0.804735528153221	1
GO:0060175	brain-derived neurotrophic factor receptor activity	7/3360	49/18639	0.142857142857143	0.792474489795918	0.804735528153221	1
GO:0043177	organic acid binding	30/3360	189/18639	0.158730158730159	0.880527210884354	0.806358257990059	1
GO:0070577	lysine-acetylated histone binding	3/3360	23/18639	0.130434782608696	0.723563664596273	0.811045504858376	1
GO:0099186	structural constituent of postsynapse	3/3360	23/18639	0.130434782608696	0.723563664596273	0.811045504858376	1
GO:0008200	ion channel inhibitor activity	6/3360	43/18639	0.13953488372093	0.774044850498339	0.812262708076611	1
GO:0005024	transforming growth factor beta receptor activity	2/3360	16/18639	0.125	0.693415178571429	0.812295937246758	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/3360	16/18639	0.125	0.693415178571429	0.812295937246758	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/3360	16/18639	0.125	0.693415178571429	0.812295937246758	1
GO:0019841	retinol binding	2/3360	16/18639	0.125	0.693415178571429	0.812295937246758	1
GO:0022841	potassium ion leak channel activity	2/3360	16/18639	0.125	0.693415178571429	0.812295937246758	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	2/3360	16/18639	0.125	0.693415178571429	0.812295937246758	1
GO:0001968	fibronectin binding	4/3360	30/18639	0.133333333333333	0.739642857142857	0.815562155496918	1
GO:0098918	structural constituent of synapse	4/3360	30/18639	0.133333333333333	0.739642857142857	0.815562155496918	1
GO:0005006	epidermal growth factor receptor activity	7/3360	50/18639	0.14	0.776625	0.821527952168206	1
GO:0005007	fibroblast growth factor receptor activity	7/3360	50/18639	0.14	0.776625	0.821527952168206	1
GO:0042562	hormone binding	14/3360	94/18639	0.148936170212766	0.826196808510638	0.822068436628104	1
GO:0022829	wide pore channel activity	5/3360	37/18639	0.135135135135135	0.749638030888031	0.822190093679231	1
GO:0042805	actinin binding	5/3360	37/18639	0.135135135135135	0.749638030888031	0.822190093679231	1
GO:0043394	proteoglycan binding	5/3360	37/18639	0.135135135135135	0.749638030888031	0.822190093679231	1
GO:0016248	channel inhibitor activity	6/3360	44/18639	0.136363636363636	0.756452922077922	0.829585344159047	1
GO:0098631	cell adhesion mediator activity	11/3360	76/18639	0.144736842105263	0.802901785714286	0.830263018714887	1
GO:0015149	hexose transmembrane transporter activity	3/3360	24/18639	0.125	0.693415178571429	0.833852247617479	1
GO:0055056	D-glucose transmembrane transporter activity	3/3360	24/18639	0.125	0.693415178571429	0.833852247617479	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/3360	24/18639	0.125	0.693415178571429	0.833852247617479	1
GO:0140033	acetylation-dependent protein binding	3/3360	24/18639	0.125	0.693415178571429	0.833852247617479	1
GO:0016411	acylglycerol O-acyltransferase activity	4/3360	31/18639	0.129032258064516	0.715783410138249	0.835580469139816	1
GO:0070325	lipoprotein particle receptor binding	4/3360	31/18639	0.129032258064516	0.715783410138249	0.835580469139816	1
GO:0005030	neurotrophin receptor activity	7/3360	51/18639	0.137254901960784	0.761397058823529	0.837168272952511	1
GO:0017110	nucleoside diphosphate phosphatase activity	2/3360	17/18639	0.117647058823529	0.652626050420168	0.838664907481746	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/3360	17/18639	0.117647058823529	0.652626050420168	0.838664907481746	1
GO:0031489	myosin V binding	2/3360	17/18639	0.117647058823529	0.652626050420168	0.838664907481746	1
GO:0036041	long-chain fatty acid binding	2/3360	17/18639	0.117647058823529	0.652626050420168	0.838664907481746	1
GO:0045236	CXCR chemokine receptor binding	2/3360	17/18639	0.117647058823529	0.652626050420168	0.838664907481746	1
GO:0042605	peptide antigen binding	6/3360	45/18639	0.133333333333333	0.739642857142857	0.84560375143344	1
GO:0141110	transporter inhibitor activity	6/3360	45/18639	0.133333333333333	0.739642857142857	0.84560375143344	1
GO:0120013	lipid transfer activity	9/3360	65/18639	0.138461538461538	0.768090659340659	0.851947608115383	1
GO:0015106	bicarbonate transmembrane transporter activity	4/3360	32/18639	0.125	0.693415178571429	0.853746424854189	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/3360	32/18639	0.125	0.693415178571429	0.853746424854189	1
GO:0120015	sterol transfer activity	4/3360	32/18639	0.125	0.693415178571429	0.853746424854189	1
GO:0015662	P-type ion transporter activity	3/3360	25/18639	0.12	0.665678571428571	0.854245495351323	1
GO:0120020	cholesterol transfer activity	3/3360	25/18639	0.12	0.665678571428571	0.854245495351323	1
GO:0140358	P-type transmembrane transporter activity	3/3360	25/18639	0.12	0.665678571428571	0.854245495351323	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	5/3360	39/18639	0.128205128205128	0.711195054945055	0.856317127768175	1
GO:0015085	calcium ion transmembrane transporter activity	22/3360	147/18639	0.149659863945578	0.830211370262391	0.860298469304801	1
GO:0004180	carboxypeptidase activity	6/3360	46/18639	0.130434782608696	0.723563664596273	0.86037387043524	1
GO:0030276	clathrin binding	6/3360	46/18639	0.130434782608696	0.723563664596273	0.86037387043524	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/3360	18/18639	0.111111111111111	0.616369047619048	0.861629785543771	1
GO:0004970	glutamate-gated receptor activity	2/3360	18/18639	0.111111111111111	0.616369047619048	0.861629785543771	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/3360	18/18639	0.111111111111111	0.616369047619048	0.861629785543771	1
GO:0050811	GABA receptor binding	2/3360	18/18639	0.111111111111111	0.616369047619048	0.861629785543771	1
GO:0004382	GDP phosphatase activity	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0004955	prostaglandin receptor activity	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0005345	purine nucleobase transmembrane transporter activity	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0008190	eukaryotic initiation factor 4E binding	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0015203	polyamine transmembrane transporter activity	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0015643	toxic substance binding	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0016868	intramolecular phosphotransferase activity	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0032395	MHC class II receptor activity	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0035374	chondroitin sulfate binding	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0043208	glycosphingolipid binding	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0051864	histone H3K36 demethylase activity	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0098505	G-rich strand telomeric DNA binding	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0140999	histone H3K4 trimethyltransferase activity	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:1990763	arrestin family protein binding	1/3360	10/18639	0.1	0.554732142857143	0.863071906845545	1
GO:0005003	ephrin receptor activity	7/3360	53/18639	0.132075471698113	0.732665094339623	0.865157081185002	1
GO:0005005	transmembrane-ephrin receptor activity	7/3360	53/18639	0.132075471698113	0.732665094339623	0.865157081185002	1
GO:0005544	calcium-dependent phospholipid binding	7/3360	53/18639	0.132075471698113	0.732665094339623	0.865157081185002	1
GO:0017046	peptide hormone binding	7/3360	53/18639	0.132075471698113	0.732665094339623	0.865157081185002	1
GO:0038064	collagen receptor activity	7/3360	53/18639	0.132075471698113	0.732665094339623	0.865157081185002	1
GO:0005126	cytokine receptor binding	43/3360	275/18639	0.156363636363636	0.867399350649351	0.86922038066215	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	4/3360	33/18639	0.121212121212121	0.672402597402597	0.870176221758945	1
GO:0030296	protein tyrosine kinase activator activity	4/3360	33/18639	0.121212121212121	0.672402597402597	0.870176221758945	1
GO:0015144	carbohydrate transmembrane transporter activity	5/3360	40/18639	0.125	0.693415178571429	0.871218443212673	1
GO:0005227	calcium-activated cation channel activity	3/3360	26/18639	0.115384615384615	0.640075549450549	0.872414368982862	1
GO:0015145	monosaccharide transmembrane transporter activity	3/3360	26/18639	0.115384615384615	0.640075549450549	0.872414368982862	1
GO:0050750	low-density lipoprotein particle receptor binding	3/3360	26/18639	0.115384615384615	0.640075549450549	0.872414368982862	1
GO:0005504	fatty acid binding	6/3360	47/18639	0.127659574468085	0.708168693009119	0.873955909308443	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/3360	19/18639	0.105263157894737	0.583928571428571	0.881560580975533	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/3360	19/18639	0.105263157894737	0.583928571428571	0.881560580975533	1
GO:0008381	mechanosensitive monoatomic ion channel activity	2/3360	19/18639	0.105263157894737	0.583928571428571	0.881560580975533	1
GO:0015245	fatty acid transmembrane transporter activity	2/3360	19/18639	0.105263157894737	0.583928571428571	0.881560580975533	1
GO:0016918	retinal binding	2/3360	19/18639	0.105263157894737	0.583928571428571	0.881560580975533	1
GO:0030506	ankyrin binding	2/3360	19/18639	0.105263157894737	0.583928571428571	0.881560580975533	1
GO:0099589	serotonin receptor activity	2/3360	19/18639	0.105263157894737	0.583928571428571	0.881560580975533	1
GO:0141147	intracellularly calcium-gated channel activity	2/3360	19/18639	0.105263157894737	0.583928571428571	0.881560580975533	1
GO:0004812	aminoacyl-tRNA ligase activity	5/3360	41/18639	0.121951219512195	0.676502613240418	0.884788805575998	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	5/3360	41/18639	0.121951219512195	0.676502613240418	0.884788805575998	1
GO:0017080	sodium channel regulator activity	5/3360	41/18639	0.121951219512195	0.676502613240418	0.884788805575998	1
GO:0015020	glucuronosyltransferase activity	4/3360	34/18639	0.117647058823529	0.652626050420168	0.884989176885103	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	4/3360	34/18639	0.117647058823529	0.652626050420168	0.884989176885103	1
GO:0015101	organic cation transmembrane transporter activity	11/3360	81/18639	0.135802469135802	0.753339947089947	0.885773953540393	1
GO:0003777	microtubule motor activity	9/3360	68/18639	0.132352941176471	0.734204306722689	0.886055154111089	1
GO:0002162	dystroglycan binding	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0004016	adenylate cyclase activity	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0004954	prostanoid receptor activity	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0005114	type II transforming growth factor beta receptor binding	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0008199	ferric iron binding	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0008432	JUN kinase binding	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0008503	benzodiazepine receptor activity	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0015205	nucleobase transmembrane transporter activity	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0032794	GTPase activating protein binding	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0042608	T cell receptor binding	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0048185	activin binding	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0050786	RAGE receptor binding	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:1990948	ubiquitin ligase inhibitor activity	1/3360	11/18639	0.0909090909090909	0.504301948051948	0.887768798412402	1
GO:0008374	O-acyltransferase activity	7/3360	55/18639	0.127272727272727	0.706022727272727	0.889068307028975	1
GO:0098632	cell-cell adhesion mediator activity	7/3360	55/18639	0.127272727272727	0.706022727272727	0.889068307028975	1
GO:0042056	chemoattractant activity	5/3360	42/18639	0.119047619047619	0.660395408163265	0.897113546064907	1
GO:0001972	retinoic acid binding	2/3360	20/18639	0.1	0.554732142857143	0.898804560560542	1
GO:0019212	phosphatase inhibitor activity	7/3360	56/18639	0.125	0.693415178571429	0.89962051926019	1
GO:0051393	alpha-actinin binding	3/3360	28/18639	0.107142857142857	0.594355867346939	0.902828300051076	1
GO:0001540	amyloid-beta binding	11/3360	83/18639	0.132530120481928	0.735187177280551	0.903375441118676	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	9/3360	70/18639	0.128571428571429	0.713227040816326	0.904975817519613	1
GO:0016782	transferase activity, transferring sulphur-containing groups	9/3360	70/18639	0.128571428571429	0.713227040816326	0.904975817519613	1
GO:0051015	actin filament binding	31/3360	209/18639	0.148325358851675	0.822808441558442	0.905488462680002	1
GO:0005078	MAP-kinase scaffold activity	1/3360	12/18639	0.0833333333333333	0.462276785714286	0.908012347764685	1
GO:0005436	sodium:phosphate symporter activity	1/3360	12/18639	0.0833333333333333	0.462276785714286	0.908012347764685	1
GO:0008504	monoamine transmembrane transporter activity	1/3360	12/18639	0.0833333333333333	0.462276785714286	0.908012347764685	1
GO:0010853	cyclase activator activity	1/3360	12/18639	0.0833333333333333	0.462276785714286	0.908012347764685	1
GO:0015132	prostaglandin transmembrane transporter activity	1/3360	12/18639	0.0833333333333333	0.462276785714286	0.908012347764685	1
GO:0017166	vinculin binding	1/3360	12/18639	0.0833333333333333	0.462276785714286	0.908012347764685	1
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/3360	12/18639	0.0833333333333333	0.462276785714286	0.908012347764685	1
GO:0097371	MDM2/MDM4 family protein binding	1/3360	12/18639	0.0833333333333333	0.462276785714286	0.908012347764685	1
GO:0005096	GTPase activator activity	41/3360	271/18639	0.151291512915129	0.839262651555087	0.910509347386334	1
GO:0015125	bile acid transmembrane transporter activity	2/3360	21/18639	0.0952380952380952	0.528316326530612	0.913682422871357	1
GO:0061891	calcium ion sensor activity	2/3360	21/18639	0.0952380952380952	0.528316326530612	0.913682422871357	1
GO:0004181	metallocarboxypeptidase activity	3/3360	29/18639	0.103448275862069	0.573860837438424	0.915433683266539	1
GO:0043236	laminin binding	3/3360	29/18639	0.103448275862069	0.573860837438424	0.915433683266539	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/3360	29/18639	0.103448275862069	0.573860837438424	0.915433683266539	1
GO:0005262	calcium channel activity	18/3360	131/18639	0.137404580152672	0.762227371864776	0.922471511440302	1
GO:0033293	monocarboxylic acid binding	10/3360	79/18639	0.126582278481013	0.702192585895118	0.923238527603762	1
GO:0005542	folic acid binding	1/3360	13/18639	0.0769230769230769	0.426717032967033	0.924605385371957	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/3360	13/18639	0.0769230769230769	0.426717032967033	0.924605385371957	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/3360	13/18639	0.0769230769230769	0.426717032967033	0.924605385371957	1
GO:0019855	calcium channel inhibitor activity	1/3360	13/18639	0.0769230769230769	0.426717032967033	0.924605385371957	1
GO:0030955	potassium ion binding	1/3360	13/18639	0.0769230769230769	0.426717032967033	0.924605385371957	1
GO:0031432	titin binding	1/3360	13/18639	0.0769230769230769	0.426717032967033	0.924605385371957	1
GO:0035325	Toll-like receptor binding	1/3360	13/18639	0.0769230769230769	0.426717032967033	0.924605385371957	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/3360	13/18639	0.0769230769230769	0.426717032967033	0.924605385371957	1
GO:0070700	BMP receptor binding	1/3360	13/18639	0.0769230769230769	0.426717032967033	0.924605385371957	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/3360	13/18639	0.0769230769230769	0.426717032967033	0.924605385371957	1
GO:0140333	glycerophospholipid flippase activity	1/3360	13/18639	0.0769230769230769	0.426717032967033	0.924605385371957	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	11/3360	86/18639	0.127906976744186	0.709541112956811	0.925499387551857	1
GO:0030159	signaling receptor complex adaptor activity	6/3360	52/18639	0.115384615384615	0.640075549450549	0.926291482196702	1
GO:0005243	gap junction channel activity	2/3360	22/18639	0.0909090909090909	0.504301948051948	0.926486590225863	1
GO:0140784	metal ion sensor activity	2/3360	22/18639	0.0909090909090909	0.504301948051948	0.926486590225863	1
GO:0001965	G-protein alpha-subunit binding	3/3360	30/18639	0.1	0.554732142857143	0.926530519685385	1
GO:0022839	monoatomic ion-gated channel activity	3/3360	30/18639	0.1	0.554732142857143	0.926530519685385	1
GO:0048019	receptor antagonist activity	3/3360	30/18639	0.1	0.554732142857143	0.926530519685385	1
GO:0005501	retinoid binding	4/3360	38/18639	0.105263157894737	0.583928571428571	0.930434333495143	1
GO:0019840	isoprenoid binding	4/3360	38/18639	0.105263157894737	0.583928571428571	0.930434333495143	1
GO:0015293	symporter activity	20/3360	146/18639	0.136986301369863	0.759907045009785	0.933894234922332	1
GO:0016500	protein-hormone receptor activity	8/3360	67/18639	0.119402985074627	0.662366737739872	0.934052989898765	1
GO:0004864	protein phosphatase inhibitor activity	6/3360	53/18639	0.113207547169811	0.627998652291105	0.934095873815217	1
GO:0047499	calcium-independent phospholipase A2 activity	3/3360	31/18639	0.0967741935483871	0.536837557603687	0.936275167958125	1
GO:0016917	GABA receptor activity	2/3360	23/18639	0.0869565217391304	0.482375776397515	0.937480979308481	1
GO:0008392	arachidonate epoxygenase activity	1/3360	14/18639	0.0714285714285714	0.396237244897959	0.938206046015693	1
GO:0008494	translation activator activity	1/3360	14/18639	0.0714285714285714	0.396237244897959	0.938206046015693	1
GO:0015926	glucosidase activity	1/3360	14/18639	0.0714285714285714	0.396237244897959	0.938206046015693	1
GO:0015171	amino acid transmembrane transporter activity	13/3360	102/18639	0.127450980392157	0.707011554621849	0.941173135013767	1
GO:0004620	phospholipase activity	14/3360	109/18639	0.128440366972477	0.7125	0.943018463260964	1
GO:0008378	galactosyltransferase activity	3/3360	32/18639	0.09375	0.520061383928571	0.944812624141291	1
GO:0047498	calcium-dependent phospholipase A2 activity	3/3360	32/18639	0.09375	0.520061383928571	0.944812624141291	1
GO:0071813	lipoprotein particle binding	3/3360	32/18639	0.09375	0.520061383928571	0.944812624141291	1
GO:0071814	protein-lipid complex binding	3/3360	32/18639	0.09375	0.520061383928571	0.944812624141291	1
GO:0015291	secondary active transmembrane transporter activity	42/3360	287/18639	0.146341463414634	0.811803135888502	0.946457078002825	1
GO:0005315	phosphate transmembrane transporter activity	2/3360	24/18639	0.0833333333333333	0.462276785714286	0.946901773098572	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/3360	24/18639	0.0833333333333333	0.462276785714286	0.946901773098572	1
GO:0019957	C-C chemokine binding	2/3360	24/18639	0.0833333333333333	0.462276785714286	0.946901773098572	1
GO:0030215	semaphorin receptor binding	2/3360	24/18639	0.0833333333333333	0.462276785714286	0.946901773098572	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	2/3360	24/18639	0.0833333333333333	0.462276785714286	0.946901773098572	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	2/3360	24/18639	0.0833333333333333	0.462276785714286	0.946901773098572	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	2/3360	24/18639	0.0833333333333333	0.462276785714286	0.946901773098572	1
GO:0070840	dynein complex binding	2/3360	24/18639	0.0833333333333333	0.462276785714286	0.946901773098572	1
GO:1901681	sulfur compound binding	40/3360	275/18639	0.145454545454545	0.806883116883117	0.947434421764035	1
GO:0016298	lipase activity	17/3360	130/18639	0.130769230769231	0.725418956043956	0.948655710324327	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/3360	15/18639	0.0666666666666667	0.369821428571429	0.949353841204271	1
GO:0004953	icosanoid receptor activity	1/3360	15/18639	0.0666666666666667	0.369821428571429	0.949353841204271	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/3360	15/18639	0.0666666666666667	0.369821428571429	0.949353841204271	1
GO:0005523	tropomyosin binding	1/3360	15/18639	0.0666666666666667	0.369821428571429	0.949353841204271	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/3360	15/18639	0.0666666666666667	0.369821428571429	0.949353841204271	1
GO:0016846	carbon-sulfur lyase activity	1/3360	15/18639	0.0666666666666667	0.369821428571429	0.949353841204271	1
GO:0017081	chloride channel regulator activity	1/3360	15/18639	0.0666666666666667	0.369821428571429	0.949353841204271	1
GO:0047372	monoacylglycerol lipase activity	1/3360	15/18639	0.0666666666666667	0.369821428571429	0.949353841204271	1
GO:0051371	muscle alpha-actinin binding	1/3360	15/18639	0.0666666666666667	0.369821428571429	0.949353841204271	1
GO:0140161	monocarboxylate:sodium symporter activity	1/3360	15/18639	0.0666666666666667	0.369821428571429	0.949353841204271	1
GO:0072341	modified amino acid binding	11/3360	91/18639	0.120879120879121	0.670555337519623	0.952781625571074	1
GO:0170055	lipid transmembrane transporter activity	6/3360	56/18639	0.107142857142857	0.594355867346939	0.953286415311223	1
GO:0015271	outward rectifier potassium channel activity	2/3360	25/18639	0.08	0.443785714285714	0.954958840728768	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/3360	25/18639	0.08	0.443785714285714	0.954958840728768	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/3360	25/18639	0.08	0.443785714285714	0.954958840728768	1
GO:0035254	glutamate receptor binding	5/3360	49/18639	0.102040816326531	0.566053206997085	0.955447528837719	1
GO:0008391	arachidonate monooxygenase activity	1/3360	16/18639	0.0625	0.346707589285714	0.958491034801439	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/3360	16/18639	0.0625	0.346707589285714	0.958491034801439	1
GO:0140328	floppase activity	1/3360	16/18639	0.0625	0.346707589285714	0.958491034801439	1
GO:0051427	hormone receptor binding	3/3360	34/18639	0.0882352941176471	0.489469537815126	0.958787918008018	1
GO:0008066	glutamate receptor activity	2/3360	26/18639	0.0769230769230769	0.426717032967033	0.961837546707593	1
GO:0030507	spectrin binding	2/3360	26/18639	0.0769230769230769	0.426717032967033	0.961837546707593	1
GO:0099106	ion channel regulator activity	21/3360	160/18639	0.13125	0.7280859375	0.961970080483959	1
GO:0004623	phospholipase A2 activity	3/3360	35/18639	0.0857142857142857	0.475484693877551	0.964458184088921	1
GO:0008429	phosphatidylethanolamine binding	1/3360	17/18639	0.0588235294117647	0.326313025210084	0.96598016775892	1
GO:0009881	photoreceptor activity	1/3360	17/18639	0.0588235294117647	0.326313025210084	0.96598016775892	1
GO:0015278	intracellularly gated calcium channel activity	1/3360	17/18639	0.0588235294117647	0.326313025210084	0.96598016775892	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/3360	17/18639	0.0588235294117647	0.326313025210084	0.96598016775892	1
GO:0030169	low-density lipoprotein particle binding	1/3360	17/18639	0.0588235294117647	0.326313025210084	0.96598016775892	1
GO:0030548	acetylcholine receptor regulator activity	1/3360	17/18639	0.0588235294117647	0.326313025210084	0.96598016775892	1
GO:0001786	phosphatidylserine binding	6/3360	59/18639	0.101694915254237	0.564134382566586	0.967276675005834	1
GO:0046943	carboxylic acid transmembrane transporter activity	25/3360	188/18639	0.132978723404255	0.737675721884498	0.967299478696587	1
GO:0035255	ionotropic glutamate receptor binding	2/3360	27/18639	0.0740740740740741	0.410912698412698	0.967700763066872	1
GO:0015294	solute:monoatomic cation symporter activity	14/3360	116/18639	0.120689655172414	0.669504310344828	0.968988522557977	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/3360	36/18639	0.0833333333333333	0.462276785714286	0.969386920728718	1
GO:0005342	organic acid transmembrane transporter activity	25/3360	189/18639	0.132275132275132	0.733772675736961	0.969572070739706	1
GO:0005253	monoatomic anion channel activity	12/3360	103/18639	0.116504854368932	0.64628987517337	0.970982793576424	1
GO:0015280	ligand-gated sodium channel activity	1/3360	18/18639	0.0555555555555556	0.308184523809524	0.972118425536281	1
GO:0022851	GABA-gated chloride ion channel activity	1/3360	18/18639	0.0555555555555556	0.308184523809524	0.972118425536281	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/3360	18/18639	0.0555555555555556	0.308184523809524	0.972118425536281	1
GO:0099602	neurotransmitter receptor regulator activity	1/3360	18/18639	0.0555555555555556	0.308184523809524	0.972118425536281	1
GO:0050698	proteoglycan sulfotransferase activity	2/3360	28/18639	0.0714285714285714	0.396237244897959	0.972690952529626	1
GO:0008009	chemokine activity	4/3360	45/18639	0.0888888888888889	0.493095238095238	0.972792269250039	1
GO:0030165	PDZ domain binding	9/3360	83/18639	0.108433734939759	0.60151678141136	0.974125816925608	1
GO:0017022	myosin binding	8/3360	76/18639	0.105263157894737	0.583928571428571	0.974794410966946	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	4/3360	46/18639	0.0869565217391304	0.482375776397515	0.976330212029236	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	5/3360	54/18639	0.0925925925925926	0.513640873015873	0.976490966267426	1
GO:0005416	amino acid:monoatomic cation symporter activity	2/3360	29/18639	0.0689655172413793	0.382573891625616	0.976932231734299	1
GO:0099604	ligand-gated calcium channel activity	2/3360	29/18639	0.0689655172413793	0.382573891625616	0.976932231734299	1
GO:0004890	GABA-A receptor activity	1/3360	19/18639	0.0526315789473684	0.291964285714286	0.977149416900767	1
GO:0008574	plus-end-directed microtubule motor activity	1/3360	19/18639	0.0526315789473684	0.291964285714286	0.977149416900767	1
GO:0031420	alkali metal ion binding	1/3360	19/18639	0.0526315789473684	0.291964285714286	0.977149416900767	1
GO:0042834	peptidoglycan binding	1/3360	19/18639	0.0526315789473684	0.291964285714286	0.977149416900767	1
GO:0000146	microfilament motor activity	3/3360	38/18639	0.0789473684210526	0.437946428571429	0.977369237745616	1
GO:0016247	channel regulator activity	21/3360	168/18639	0.125	0.693415178571429	0.979651329629997	1
GO:0005543	phospholipid binding	73/3360	497/18639	0.146881287726358	0.814797714860592	0.980427796596034	1
GO:0020037	heme binding	17/3360	142/18639	0.119718309859155	0.664115945674044	0.981158753462734	1
GO:0001614	purinergic nucleotide receptor activity	1/3360	20/18639	0.05	0.277366071428571	0.981272830392358	1
GO:0005326	neurotransmitter transmembrane transporter activity	1/3360	20/18639	0.05	0.277366071428571	0.981272830392358	1
GO:0016502	nucleotide receptor activity	1/3360	20/18639	0.05	0.277366071428571	0.981272830392358	1
GO:0030627	pre-mRNA 5'-splice site binding	1/3360	20/18639	0.05	0.277366071428571	0.981272830392358	1
GO:0038187	pattern recognition receptor activity	4/3360	48/18639	0.0833333333333333	0.462276785714286	0.98214690827808	1
GO:0141108	transporter regulator activity	21/3360	170/18639	0.123529411764706	0.685257352941177	0.982714757668002	1
GO:0005452	solute:inorganic anion antiporter activity	2/3360	31/18639	0.0645161290322581	0.357891705069124	0.983584573752154	1
GO:0005248	voltage-gated sodium channel activity	1/3360	21/18639	0.0476190476190476	0.264158163265306	0.984652350768408	1
GO:0008373	sialyltransferase activity	1/3360	21/18639	0.0476190476190476	0.264158163265306	0.984652350768408	1
GO:0015174	basic amino acid transmembrane transporter activity	1/3360	21/18639	0.0476190476190476	0.264158163265306	0.984652350768408	1
GO:0036122	BMP binding	1/3360	21/18639	0.0476190476190476	0.264158163265306	0.984652350768408	1
GO:0051428	peptide hormone receptor binding	1/3360	21/18639	0.0476190476190476	0.264158163265306	0.984652350768408	1
GO:0004896	cytokine receptor activity	10/3360	96/18639	0.104166666666667	0.577845982142857	0.986117563692905	1
GO:0001664	G protein-coupled receptor binding	40/3360	297/18639	0.134680134680135	0.747113997113997	0.986139595542651	1
GO:0061134	peptidase regulator activity	29/3360	226/18639	0.128318584070796	0.711824431099874	0.986352009781601	1
GO:0015377	chloride:monoatomic cation symporter activity	1/3360	22/18639	0.0454545454545455	0.252150974025974	0.987422148889482	1
GO:0033691	sialic acid binding	1/3360	22/18639	0.0454545454545455	0.252150974025974	0.987422148889482	1
GO:0015459	potassium channel regulator activity	5/3360	59/18639	0.0847457627118644	0.470111985472155	0.987945028690649	1
GO:0005254	chloride channel activity	8/3360	83/18639	0.0963855421686747	0.534681583476764	0.988764785988936	1
GO:0005283	amino acid:sodium symporter activity	1/3360	23/18639	0.0434782608695652	0.241187888198758	0.989692202052255	1
GO:0016493	C-C chemokine receptor activity	1/3360	23/18639	0.0434782608695652	0.241187888198758	0.989692202052255	1
GO:0043274	phospholipase binding	1/3360	23/18639	0.0434782608695652	0.241187888198758	0.989692202052255	1
GO:0019825	oxygen binding	2/3360	34/18639	0.0588235294117647	0.326313025210084	0.990204028917847	1
GO:0030547	signaling receptor inhibitor activity	3/3360	44/18639	0.0681818181818182	0.378226461038961	0.991082073887307	1
GO:0030552	cAMP binding	1/3360	24/18639	0.0416666666666667	0.231138392857143	0.991552655485024	1
GO:0070300	phosphatidic acid binding	1/3360	24/18639	0.0416666666666667	0.231138392857143	0.991552655485024	1
GO:0005343	organic acid:sodium symporter activity	2/3360	35/18639	0.0571428571428571	0.316989795918367	0.991764383149903	1
GO:0046906	tetrapyrrole binding	17/3360	152/18639	0.111842105263158	0.620424107142857	0.992472754373547	1
GO:0005251	delayed rectifier potassium channel activity	1/3360	25/18639	0.04	0.221892857142857	0.993077397766534	1
GO:0003730	mRNA 3'-UTR binding	33/3360	262/18639	0.125954198473282	0.698708424209378	0.993389984165963	1
GO:0003779	actin binding	61/3360	443/18639	0.137697516930023	0.763852386326991	0.993650790081485	1
GO:0048306	calcium-dependent protein binding	7/3360	80/18639	0.0875	0.485390625	0.993742839807677	1
GO:0042379	chemokine receptor binding	6/3360	72/18639	0.0833333333333333	0.462276785714286	0.993758339602681	1
GO:0030551	cyclic nucleotide binding	2/3360	37/18639	0.0540540540540541	0.299855212355212	0.994190238977417	1
GO:0001637	G protein-coupled chemoattractant receptor activity	1/3360	26/18639	0.0384615384615385	0.213358516483517	0.994326991808892	1
GO:0004950	chemokine receptor activity	1/3360	26/18639	0.0384615384615385	0.213358516483517	0.994326991808892	1
GO:0043548	phosphatidylinositol 3-kinase binding	1/3360	26/18639	0.0384615384615385	0.213358516483517	0.994326991808892	1
GO:0008083	growth factor activity	18/3360	162/18639	0.111111111111111	0.616369047619048	0.994330472665212	1
GO:0099095	ligand-gated monoatomic anion channel activity	3/3360	47/18639	0.0638297872340425	0.354084346504559	0.994468628146408	1
GO:0008509	monoatomic anion transmembrane transporter activity	16/3360	149/18639	0.10738255033557	0.59568552253116	0.994943571891841	1
GO:0008395	steroid hydroxylase activity	1/3360	27/18639	0.037037037037037	0.205456349206349	0.995351077529739	1
GO:0015252	proton channel activity	1/3360	27/18639	0.037037037037037	0.205456349206349	0.995351077529739	1
GO:0008201	heparin binding	19/3360	172/18639	0.11046511627907	0.612785506644518	0.995724150336687	1
GO:0005539	glycosaminoglycan binding	29/3360	242/18639	0.119834710743802	0.66476165879575	0.996119943986885	1
GO:0005242	inward rectifier potassium channel activity	1/3360	28/18639	0.0357142857142857	0.19811862244898	0.996190341418632	1
GO:0048020	CCR chemokine receptor binding	3/3360	50/18639	0.06	0.332839285714286	0.99659249852064	1
GO:0035250	UDP-galactosyltransferase activity	1/3360	29/18639	0.0344827586206897	0.191286945812808	0.996878131050215	1
GO:0004866	endopeptidase inhibitor activity	17/3360	161/18639	0.105590062111801	0.585742014196983	0.996885595321616	1
GO:0005272	sodium channel activity	3/3360	51/18639	0.0588235294117647	0.326313025210084	0.997104662018659	1
GO:0008227	G protein-coupled amine receptor activity	2/3360	41/18639	0.0487804878048781	0.270601045296167	0.9971286315105	1
GO:0061135	endopeptidase regulator activity	20/3360	184/18639	0.108695652173913	0.602969720496894	0.997334610485498	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/3360	30/18639	0.0333333333333333	0.184910714285714	0.997441778533895	1
GO:0008146	sulfotransferase activity	3/3360	53/18639	0.0566037735849057	0.313999326145553	0.997913680163006	1
GO:0015103	inorganic anion transmembrane transporter activity	17/3360	165/18639	0.103030303030303	0.571542207792208	0.997929101631437	1
GO:0008236	serine-type peptidase activity	21/3360	194/18639	0.108247422680412	0.60048324742268	0.997985512963988	1
GO:0046873	metal ion transmembrane transporter activity	59/3360	450/18639	0.131111111111111	0.727315476190476	0.998186855358397	1
GO:0017171	serine hydrolase activity	21/3360	198/18639	0.106060606060606	0.588352272727273	0.998635509089207	1
GO:0030414	peptidase inhibitor activity	17/3360	169/18639	0.100591715976331	0.558014581572274	0.998635534202165	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/3360	56/18639	0.0535714285714286	0.297177933673469	0.998729633586054	1
GO:0015081	sodium ion transmembrane transporter activity	16/3360	164/18639	0.0975609756097561	0.541202090592334	0.998944554639604	1
GO:0005244	voltage-gated monoatomic ion channel activity	17/3360	173/18639	0.0982658959537572	0.545112510322048	0.99910884787626	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/3360	36/18639	0.0277777777777778	0.154092261904762	0.999225589989445	1
GO:0022832	voltage-gated channel activity	17/3360	175/18639	0.0971428571428571	0.538882653061225	0.99928209827774	1
GO:0015370	solute:sodium symporter activity	5/3360	79/18639	0.0632911392405063	0.351096292947559	0.999328399468483	1
GO:0004252	serine-type endopeptidase activity	17/3360	176/18639	0.0965909090909091	0.535820819805195	0.999356150362569	1
GO:0030280	structural constituent of skin epidermis	1/3360	37/18639	0.027027027027027	0.149927606177606	0.99936546085089	1
GO:0022824	transmitter-gated monoatomic ion channel activity	3/3360	63/18639	0.0476190476190476	0.264158163265306	0.999608175323331	1
GO:0022835	transmitter-gated channel activity	3/3360	63/18639	0.0476190476190476	0.264158163265306	0.999608175323331	1
GO:0071855	neuropeptide receptor binding	1/3360	40/18639	0.025	0.138683035714286	0.999650948159555	1
GO:0022843	voltage-gated monoatomic cation channel activity	12/3360	143/18639	0.0839160839160839	0.465509490509491	0.999660915045645	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/3360	53/18639	0.0377358490566038	0.209332884097035	0.999667959732015	1
GO:0015079	potassium ion transmembrane transporter activity	14/3360	160/18639	0.0875	0.485390625	0.999707490296881	1
GO:0001653	peptide receptor activity	10/3360	128/18639	0.078125	0.433384486607143	0.999708937806884	1
GO:0005200	structural constituent of cytoskeleton	8/3360	112/18639	0.0714285714285714	0.396237244897959	0.999738797824213	1
GO:0015108	chloride transmembrane transporter activity	9/3360	121/18639	0.0743801652892562	0.412610684769776	0.999756051008507	1
GO:0004867	serine-type endopeptidase inhibitor activity	6/3360	95/18639	0.0631578947368421	0.350357142857143	0.999761388311446	1
GO:0008528	G protein-coupled peptide receptor activity	9/3360	122/18639	0.0737704918032787	0.409228629976581	0.999786934727563	1
GO:0004497	monooxygenase activity	7/3360	106/18639	0.0660377358490566	0.366332547169811	0.999822640148051	1
GO:0030594	neurotransmitter receptor activity	6/3360	97/18639	0.0618556701030928	0.343133284241532	0.999823033177704	1
GO:0005267	potassium channel activity	9/3360	124/18639	0.0725806451612903	0.402628168202765	0.999837717579611	1
GO:0005125	cytokine activity	23/3360	234/18639	0.0982905982905983	0.545249542124542	0.999846626937881	1
GO:0098960	postsynaptic neurotransmitter receptor activity	3/3360	69/18639	0.0434782608695652	0.241187888198758	0.999859553150808	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/3360	73/18639	0.0410958904109589	0.227972113502935	0.999929679940735	1
GO:0140375	immune receptor activity	12/3360	156/18639	0.0769230769230769	0.426717032967033	0.999935024625724	1
GO:0005249	voltage-gated potassium channel activity	5/3360	98/18639	0.0510204081632653	0.283026603498542	0.999965432193638	1
GO:0005261	monoatomic cation channel activity	33/3360	341/18639	0.0967741935483871	0.536837557603687	0.999995172169549	1
GO:0099094	ligand-gated monoatomic cation channel activity	7/3360	136/18639	0.0514705882352941	0.285523897058823	0.99999810441775	1
GO:0005216	monoatomic ion channel activity	45/3360	448/18639	0.100446428571429	0.557208625637755	0.999999303588935	1
GO:0022834	ligand-gated channel activity	11/3360	188/18639	0.0585106382978723	0.324577317629179	0.999999778300013	1
GO:0022836	gated channel activity	26/3360	318/18639	0.0817610062893082	0.453554582210243	0.999999850664396	1
GO:0003823	antigen binding	9/3360	174/18639	0.0517241379310345	0.286930418719212	0.999999894296184	1
GO:0015276	ligand-gated monoatomic ion channel activity	10/3360	186/18639	0.0537634408602151	0.298243087557604	0.999999926702717	1
GO:0030527	structural constituent of chromatin	1/3360	98/18639	0.0102040816326531	0.0566053206997085	0.999999996723285	1
GO:0005179	hormone activity	1/3360	132/18639	0.00757575757575758	0.0420251623376623	0.999999999996367	1
GO:0030371	translation repressor activity	6/3360	329/18639	0.0182370820668693	0.10116695614416	1	1
GO:0045182	translation regulator activity	8/3360	356/18639	0.0224719101123595	0.124658908507223	1	1