ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0005525	GTP binding	137/4017	378/18639	0.362433862433862	1.68170394869424	2.94012842114427e-11	2.85246019793625e-08
GO:0043021	ribonucleoprotein complex binding	77/4017	177/18639	0.435028248587571	2.01854406906242	4.2669561674439e-11	2.85246019793625e-08
GO:0140098	catalytic activity, acting on RNA	137/4017	387/18639	0.354005167958656	1.64259455453856	1.90308937514018e-10	8.48143498187474e-08
GO:0051082	unfolded protein binding	57/4017	121/18639	0.471074380165289	2.18579919639055	3.5272182702704e-10	1.17897270683788e-07
GO:0019001	guanyl nucleotide binding	138/4017	400/18639	0.345	1.60081030619866	1.17720881726842e-09	2.62321364781312e-07
GO:0032561	guanyl ribonucleotide binding	138/4017	400/18639	0.345	1.60081030619866	1.17720881726842e-09	2.62321364781312e-07
GO:0043022	ribosome binding	52/4017	112/18639	0.464285714285714	2.15429958391123	3.89303496332604e-09	7.43569677995274e-07
GO:0016853	isomerase activity	73/4017	180/18639	0.405555555555556	1.88178989295494	5.79650137639699e-09	9.68740292530347e-07
GO:0140101	catalytic activity, acting on a tRNA	60/4017	139/18639	0.431654676258993	2.00289059267896	8.26593312635765e-09	1.19651033401366e-06
GO:0003924	GTPase activity	116/4017	331/18639	0.350453172205438	1.62611318813472	8.9492171579182e-09	1.19651033401366e-06
GO:0016755	aminoacyltransferase activity	160/4017	496/18639	0.32258064516129	1.49678383001277	1.35243756270491e-08	1.64382638303315e-06
GO:0019787	ubiquitin-like protein transferase activity	154/4017	479/18639	0.321503131524008	1.49178413454717	3.22347506075272e-08	3.59148846352199e-06
GO:0004842	ubiquitin-protein transferase activity	143/4017	449/18639	0.318485523385301	1.47778234263844	1.86667899733277e-07	1.9198075534107e-05
GO:0061650	ubiquitin-like protein conjugating enzyme activity	24/4017	41/18639	0.585365853658537	2.71611504763293	2.91453332721628e-07	2.78337932749155e-05
GO:0019003	GDP binding	36/4017	75/18639	0.48	2.227214339059	3.36426674538621e-07	2.99868309238757e-05
GO:0015036	disulfide oxidoreductase activity	23/4017	40/18639	0.575	2.66801717699776	8.01710635362387e-07	6.69929449674695e-05
GO:0016779	nucleotidyltransferase activity	54/4017	136/18639	0.397058823529412	1.84236480253042	1.16907307343002e-06	9.19441587750553e-05
GO:0051537	2 iron, 2 sulfur cluster binding	18/4017	28/18639	0.642857142857143	2.98287634695402	1.32826934552341e-06	9.8660895275822e-05
GO:0008135	translation factor activity, RNA binding	37/4017	83/18639	0.44578313253012	2.06844705183692	2.25167332776977e-06	0.000153047320552305
GO:0016860	intramolecular oxidoreductase activity	27/4017	53/18639	0.509433962264151	2.36378880324658	2.28941392000457e-06	0.000153047320552305
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	62/4017	167/18639	0.37125748502994	1.72264582112847	2.91155328978209e-06	0.000185368892782793
GO:0180051	translation factor activity	37/4017	84/18639	0.44047619047619	2.0438226821722	3.19371757587917e-06	0.00019409092722502
GO:0003925	G protein activity	27/4017	54/18639	0.5	2.32001493651979	3.64131680727443e-06	0.000202851690471913
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	27/4017	54/18639	0.5	2.32001493651979	3.64131680727443e-06	0.000202851690471913
GO:0140662	ATP-dependent protein folding chaperone	22/4017	40/18639	0.55	2.55201643017177	3.83712070561347e-06	0.000205209215336209
GO:0016741	transferase activity, transferring one-carbon groups	75/4017	215/18639	0.348837209302326	1.61861507199055	4.32409816920491e-06	0.00022235843277796
GO:0061631	ubiquitin conjugating enzyme activity	20/4017	35/18639	0.571428571428571	2.6514456417369	4.80825372965274e-06	0.000238097601353545
GO:0051536	iron-sulfur cluster binding	34/4017	76/18639	0.447368421052632	2.07580283793876	5.20200280758226e-06	0.000248395634062053
GO:0000049	tRNA binding	35/4017	80/18639	0.4375	2.03001306945482	7.02665235938797e-06	0.000323952903603507
GO:0051540	metal cluster binding	34/4017	77/18639	0.441558441558442	2.04884435952397	7.39788139709876e-06	0.000329698914264035
GO:0030145	manganese ion binding	31/4017	68/18639	0.455882352941176	2.11530773623863	8.34179111186233e-06	0.000359773377953546
GO:0008168	methyltransferase activity	70/4017	204/18639	0.343137254901961	1.5921671132979	1.6701666348478e-05	0.000697816497122347
GO:0008173	RNA methyltransferase activity	30/4017	67/18639	0.447761194029851	2.07762531628638	1.79629273387288e-05	0.000727770722784255
GO:0044389	ubiquitin-like protein ligase binding	101/4017	322/18639	0.313664596273292	1.45541309682297	2.27368896316264e-05	0.000894094748161308
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	48/4017	128/18639	0.375	1.74001120238984	2.70798418135833e-05	0.00103444995727888
GO:0044183	protein folding chaperone	32/4017	75/18639	0.426666666666667	1.97974607916356	3.16865787231196e-05	0.00117680432646697
GO:0031625	ubiquitin protein ligase binding	95/4017	302/18639	0.314569536423841	1.45961204615484	3.46192183055421e-05	0.00125097013174351
GO:0015035	protein-disulfide reductase activity	18/4017	34/18639	0.529411764705882	2.4564864033739	5.78205300782987e-05	0.00203436970301803
GO:0016763	pentosyltransferase activity	23/4017	49/18639	0.469387755102041	2.17797320571246	6.8066167825736e-05	0.00233344785597459
GO:0009055	electron transfer activity	43/4017	116/18639	0.370689655172414	1.72001107362674	9.45582335793975e-05	0.00316060895739136
GO:0003756	protein disulfide isomerase activity	12/4017	19/18639	0.631578947368421	2.93054518297237	0.000106978028768051	0.0034054672491163
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	12/4017	19/18639	0.631578947368421	2.93054518297237	0.000106978028768051	0.0034054672491163
GO:0000287	magnesium ion binding	74/4017	230/18639	0.321739130434783	1.49287917654317	0.000110164497616434	0.00342534728635285
GO:0005048	signal sequence binding	23/4017	51/18639	0.450980392156863	2.09256249176295	0.000145952787147843	0.00443497446401515
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	26/4017	61/18639	0.426229508196721	1.97771765080376	0.000173471857705106	0.00515404163892727
GO:0140104	molecular carrier activity	78/4017	249/18639	0.313253012048193	1.45350333372324	0.000192495385193623	0.00559492021747552
GO:0019843	rRNA binding	27/4017	65/18639	0.415384615384615	1.92739702418567	0.000219853589333407	0.00625413295614395
GO:0008175	tRNA methyltransferase activity	17/4017	34/18639	0.5	2.32001493651979	0.000231368677771765	0.00644458171210105
GO:0070063	RNA polymerase binding	25/4017	59/18639	0.423728813559322	1.96611435298287	0.000256690504368133	0.00700398376204477
GO:0030515	snoRNA binding	16/4017	32/18639	0.5	2.32001493651979	0.000352473036634047	0.00942512899959441
GO:0061659	ubiquitin-like protein ligase activity	108/4017	372/18639	0.290322580645161	1.34710544701149	0.000374620106663098	0.00982092318840318
GO:0019207	kinase regulator activity	86/4017	287/18639	0.299651567944251	1.39039222676447	0.000480157524614639	0.0123455886617264
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	71/4017	229/18639	0.310043668122271	1.43861188203411	0.000504149973237267	0.0127178964946835
GO:0003727	single-stranded RNA binding	33/4017	89/18639	0.370786516853933	1.72046051472254	0.000582826127892137	0.0144303432035516
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	12/4017	22/18639	0.545454545454545	2.53092538529432	0.000713667556583683	0.0171741445518954
GO:0019887	protein kinase regulator activity	77/4017	255/18639	0.301960784313725	1.40110705970215	0.000719335897461587	0.0171741445518954
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	18/4017	40/18639	0.45	2.08801344286781	0.000777828267043288	0.018244849000647
GO:0003735	structural constituent of ribosome	56/4017	175/18639	0.32	1.48480955937267	0.000818302423846271	0.0186307013326085
GO:0016866	intramolecular transferase activity	14/4017	28/18639	0.5	2.32001493651979	0.000822147627990949	0.0186307013326085
GO:0008170	N-methyltransferase activity	35/4017	98/18639	0.357142857142857	1.65715352608556	0.000894295465931403	0.0199278839658381
GO:0004527	exonuclease activity	31/4017	84/18639	0.369047619047619	1.71239197695508	0.000922643715333636	0.0202225352032963
GO:0031072	heat shock protein binding	44/4017	131/18639	0.33587786259542	1.55848331613543	0.000949771312931792	0.0204813587966098
GO:0061630	ubiquitin protein ligase activity	101/4017	353/18639	0.286118980169972	1.32760061523229	0.000975408236429246	0.0205619283777717
GO:0004300	enoyl-CoA hydratase activity	8/4017	12/18639	0.666666666666667	3.09335324869305	0.000984265831097524	0.0205619283777717
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	12/4017	23/18639	0.521739130434783	2.42088515115109	0.00120091856910569	0.0241067678158101
GO:0003743	translation initiation factor activity	21/4017	51/18639	0.411764705882353	1.91060053595747	0.00122016870560827	0.0241067678158101
GO:0016407	acetyltransferase activity	34/4017	96/18639	0.354166666666667	1.64334391336819	0.00124164337602843	0.0241067678158101
GO:0022884	macromolecule transmembrane transporter activity	15/4017	32/18639	0.46875	2.1750140029873	0.00126213444061833	0.0241067678158101
GO:0070717	poly-purine tract binding	15/4017	32/18639	0.46875	2.1750140029873	0.00126213444061833	0.0241067678158101
GO:0140142	nucleocytoplasmic carrier activity	15/4017	32/18639	0.46875	2.1750140029873	0.00126213444061833	0.0241067678158101
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	20/4017	48/18639	0.416666666666667	1.93334578043316	0.00132951854321402	0.0250361449616498
GO:0000774	adenyl-nucleotide exchange factor activity	9/4017	15/18639	0.6	2.78401792382375	0.00138288191839422	0.0253414675949335
GO:0008641	ubiquitin-like modifier activating enzyme activity	7/4017	10/18639	0.7	3.24802091112771	0.00138364033988791	0.0253414675949335
GO:0005484	SNAP receptor activity	16/4017	36/18639	0.444444444444444	2.0622354991287	0.00176844025164687	0.0307065534604139
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	16/4017	36/18639	0.444444444444444	2.0622354991287	0.00176844025164687	0.0307065534604139
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	16/4017	36/18639	0.444444444444444	2.0622354991287	0.00176844025164687	0.0307065534604139
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	16/4017	36/18639	0.444444444444444	2.0622354991287	0.00176844025164687	0.0307065534604139
GO:0060590	ATPase regulator activity	20/4017	49/18639	0.408163265306122	1.89388974409779	0.00179680598497754	0.0307990974604483
GO:0008320	protein transmembrane transporter activity	13/4017	27/18639	0.481481481481481	2.23408845738943	0.00195334164952756	0.0328606091987642
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	19/4017	46/18639	0.41304347826087	1.91653407799461	0.00196622942101805	0.0328606091987642
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	8/4017	13/18639	0.615384615384615	2.85540299879359	0.0020756346188019	0.0334352227149174
GO:0009982	pseudouridine synthase activity	8/4017	13/18639	0.615384615384615	2.85540299879359	0.0020756346188019	0.0334352227149174
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	8/4017	13/18639	0.615384615384615	2.85540299879359	0.0020756346188019	0.0334352227149174
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	23/4017	60/18639	0.383333333333333	1.77867811799851	0.00228101981037574	0.0356793887627394
GO:0004532	RNA exonuclease activity	17/4017	40/18639	0.425	1.97201269604182	0.00232169545426951	0.0356793887627394
GO:0061791	GTPase motor activity	17/4017	40/18639	0.425	1.97201269604182	0.00232169545426951	0.0356793887627394
GO:1990606	membrane scission GTPase motor activity	17/4017	40/18639	0.425	1.97201269604182	0.00232169545426951	0.0356793887627394
GO:0003712	transcription coregulator activity	133/4017	495/18639	0.268686868686869	1.24671509720053	0.00257815374714509	0.0391703586356021
GO:0051287	NAD binding	21/4017	54/18639	0.388888888888889	1.80445606173762	0.00283565390012355	0.0425985310614067
GO:0016757	glycosyltransferase activity	77/4017	267/18639	0.288389513108614	1.33813595589531	0.00290376106979924	0.043136983892462
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	25/4017	68/18639	0.367647058823529	1.70589333567632	0.00293694106383701	0.0431504417840669
GO:0140517	protein-RNA adaptor activity	11/4017	22/18639	0.5	2.32001493651979	0.0029780589944574	0.0432789660390168
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	7/4017	11/18639	0.636363636363636	2.95274628284337	0.00309658154271114	0.0440439310915404
GO:0140537	transcription regulator activator activity	7/4017	11/18639	0.636363636363636	2.95274628284337	0.00309658154271114	0.0440439310915404
GO:0016830	carbon-carbon lyase activity	20/4017	51/18639	0.392156862745098	1.81961955805474	0.00315450246780069	0.0442892182668802
GO:0140318	protein transporter activity	17/4017	41/18639	0.414634146341463	1.92391482540666	0.00318007849934219	0.0442892182668802
GO:0008408	3'-5' exonuclease activity	22/4017	58/18639	0.379310344827586	1.76001133115294	0.00327820209352042	0.0451851154539876
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	16/4017	38/18639	0.421052631578947	1.95369678864825	0.00346444969220879	0.0468291443130572
GO:0016410	N-acyltransferase activity	32/4017	94/18639	0.340425531914894	1.5795846376305	0.00348011538180133	0.0468291443130572
GO:0140767	enzyme-substrate adaptor activity	44/4017	139/18639	0.316546762589928	1.46878643463123	0.00350255380052784	0.0468291443130572
GO:0008080	N-acetyltransferase activity	25/4017	69/18639	0.36231884057971	1.68117024385492	0.0036781502113356	0.0486899686391654
GO:0051539	4 iron, 4 sulfur cluster binding	18/4017	45/18639	0.4	1.85601194921583	0.0038796331141068	0.0508536222898117
GO:0043539	protein serine/threonine kinase activator activity	26/4017	73/18639	0.356164383561644	1.65261337943875	0.00404264900055713	0.0524759389683969
GO:0004860	protein kinase inhibitor activity	29/4017	84/18639	0.345238095238095	1.60191507521605	0.00418109982948056	0.0537512545386107
GO:0016859	cis-trans isomerase activity	17/4017	42/18639	0.404761904761905	1.87810732956364	0.00428505258982679	0.0545130620922703
GO:0032977	membrane insertase activity	9/4017	17/18639	0.529411764705882	2.4564864033739	0.00440344854597247	0.0545130620922703
GO:0051787	misfolded protein binding	9/4017	17/18639	0.529411764705882	2.4564864033739	0.00440344854597247	0.0545130620922703
GO:0070402	NADPH binding	9/4017	17/18639	0.529411764705882	2.4564864033739	0.00440344854597247	0.0545130620922703
GO:0097602	cullin family protein binding	12/4017	26/18639	0.461538461538462	2.14155224909519	0.00448442946267699	0.0547964993394305
GO:0043024	ribosomal small subunit binding	10/4017	20/18639	0.5	2.32001493651979	0.00460141509372953	0.0547964993394305
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	11/4017	23/18639	0.478260869565217	2.2191447218885	0.00460710438436315	0.0547964993394305
GO:0140103	catalytic activity, acting on a glycoprotein	11/4017	23/18639	0.478260869565217	2.2191447218885	0.00460710438436315	0.0547964993394305
GO:0004722	protein serine/threonine phosphatase activity	34/4017	103/18639	0.330097087378641	1.53166034644025	0.00463126733384865	0.0547964993394305
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	16/4017	39/18639	0.41025641025641	1.90360199919573	0.00471585685221603	0.0553079001001125
GO:0140597	protein carrier chaperone	56/4017	188/18639	0.297872340425532	1.38213655792668	0.00485661117532632	0.0564633838383591
GO:0000993	RNA polymerase II complex binding	15/4017	36/18639	0.416666666666667	1.93334578043316	0.00516649372981267	0.0592017365989418
GO:0051087	protein-folding chaperone binding	42/4017	134/18639	0.313432835820896	1.45433772140047	0.00518070544657905	0.0592017365989418
GO:0016251	RNA polymerase II general transcription initiation factor activity	20/4017	53/18639	0.377358490566038	1.75095466907154	0.00527731107068824	0.0597946178094083
GO:0140297	DNA-binding transcription factor binding	129/4017	488/18639	0.264344262295082	1.22656527381579	0.00537530000107965	0.0599877482024043
GO:0016791	phosphatase activity	77/4017	273/18639	0.282051282051282	1.30872637444706	0.00538409108772514	0.0599877482024043
GO:0005049	nuclear export signal receptor activity	7/4017	12/18639	0.583333333333333	2.70668409260642	0.00605382353897021	0.0645481152857745
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	7/4017	12/18639	0.583333333333333	2.70668409260642	0.00605382353897021	0.0645481152857745
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	7/4017	12/18639	0.583333333333333	2.70668409260642	0.00605382353897021	0.0645481152857745
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	7/4017	12/18639	0.583333333333333	2.70668409260642	0.00605382353897021	0.0645481152857745
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	7/4017	12/18639	0.583333333333333	2.70668409260642	0.00605382353897021	0.0645481152857745
GO:0035925	mRNA 3'-UTR AU-rich region binding	13/4017	30/18639	0.433333333333333	2.01067961165049	0.006083068456251	0.0645481152857745
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	8/4017	15/18639	0.533333333333333	2.47468259895444	0.0068438017385215	0.0720485269638051
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	28/4017	83/18639	0.337349397590361	1.56531128247118	0.00691638442639478	0.0722437967038267
GO:0003746	translation elongation factor activity	9/4017	18/18639	0.5	2.32001493651979	0.00713844808875375	0.0734161930358751
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	9/4017	18/18639	0.5	2.32001493651979	0.00713844808875375	0.0734161930358751
GO:0003954	NADH dehydrogenase activity	17/4017	44/18639	0.386363636363636	1.79273881458347	0.00743741594103598	0.0751303595610733
GO:0016790	thiolester hydrolase activity	17/4017	44/18639	0.386363636363636	1.79273881458347	0.00743741594103598	0.0751303595610733
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	21/4017	58/18639	0.362068965517241	1.68001081610054	0.00747370068932143	0.0751303595610733
GO:0016831	carboxy-lyase activity	14/4017	34/18639	0.411764705882353	1.91060053595747	0.00769876370145685	0.0768152766331926
GO:0008276	protein methyltransferase activity	31/4017	95/18639	0.326315789473684	1.51411501120239	0.00799102552309313	0.0791407490694482
GO:0070273	phosphatidylinositol-4-phosphate binding	13/4017	31/18639	0.419354838709677	1.9458189790166	0.00844126412835633	0.0829850745559737
GO:0004518	nuclease activity	60/4017	209/18639	0.287081339712919	1.33206599226017	0.00867931009337082	0.0847024641958889
GO:0016427	tRNA (cytidine) methyltransferase activity	6/4017	10/18639	0.6	2.78401792382375	0.00933935753445133	0.084987101553074
GO:0033204	ribonuclease P RNA binding	6/4017	10/18639	0.6	2.78401792382375	0.00933935753445133	0.084987101553074
GO:0047429	nucleoside triphosphate diphosphatase activity	6/4017	10/18639	0.6	2.78401792382375	0.00933935753445133	0.084987101553074
GO:0033192	calmodulin-dependent protein phosphatase activity	27/4017	81/18639	0.333333333333333	1.54667662434653	0.0094076971053515	0.084987101553074
GO:0140791	histone H2AXS140 phosphatase activity	27/4017	81/18639	0.333333333333333	1.54667662434653	0.0094076971053515	0.084987101553074
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	27/4017	81/18639	0.333333333333333	1.54667662434653	0.0094076971053515	0.084987101553074
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	27/4017	81/18639	0.333333333333333	1.54667662434653	0.0094076971053515	0.084987101553074
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	27/4017	81/18639	0.333333333333333	1.54667662434653	0.0094076971053515	0.084987101553074
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	27/4017	81/18639	0.333333333333333	1.54667662434653	0.0094076971053515	0.084987101553074
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	27/4017	81/18639	0.333333333333333	1.54667662434653	0.0094076971053515	0.084987101553074
GO:1990439	MAP kinase serine/threonine phosphatase activity	27/4017	81/18639	0.333333333333333	1.54667662434653	0.0094076971053515	0.084987101553074
GO:0015399	primary active transmembrane transporter activity	49/4017	166/18639	0.295180722891566	1.36964737216229	0.00961617023758063	0.0862873799170826
GO:0000175	3'-5'-RNA exonuclease activity	14/4017	35/18639	0.4	1.85601194921583	0.0103308474264879	0.0914724702596975
GO:0140566	histone reader activity	14/4017	35/18639	0.4	1.85601194921583	0.0103308474264879	0.0914724702596975
GO:0008649	rRNA methyltransferase activity	10/4017	22/18639	0.454545454545455	2.10910448774526	0.0105467982068046	0.0915653844318036
GO:0034062	5'-3' RNA polymerase activity	10/4017	22/18639	0.454545454545455	2.10910448774526	0.0105467982068046	0.0915653844318036
GO:0097747	RNA polymerase activity	10/4017	22/18639	0.454545454545455	2.10910448774526	0.0105467982068046	0.0915653844318036
GO:0043175	RNA polymerase core enzyme binding	16/4017	42/18639	0.380952380952381	1.7676304278246	0.0107971830721077	0.0919309251453714
GO:0032182	ubiquitin-like protein binding	37/4017	120/18639	0.308333333333333	1.43067587752054	0.0109963740273185	0.0919309251453714
GO:0120227	acyl-CoA binding	9/4017	19/18639	0.473684210526316	2.19790888722928	0.0110018167034143	0.0919309251453714
GO:0016722	oxidoreductase activity, acting on metal ions	8/4017	16/18639	0.5	2.32001493651979	0.0111292046149798	0.0919309251453714
GO:0030275	LRR domain binding	8/4017	16/18639	0.5	2.32001493651979	0.0111292046149798	0.0919309251453714
GO:0043023	ribosomal large subunit binding	8/4017	16/18639	0.5	2.32001493651979	0.0111292046149798	0.0919309251453714
GO:0097027	ubiquitin-protein transferase activator activity	8/4017	16/18639	0.5	2.32001493651979	0.0111292046149798	0.0919309251453714
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	27/4017	82/18639	0.329268292682927	1.52781471429352	0.0112077343296152	0.0919309251453714
GO:0033549	MAP kinase phosphatase activity	27/4017	82/18639	0.329268292682927	1.52781471429352	0.0112077343296152	0.0919309251453714
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	21/4017	60/18639	0.35	1.62401045556385	0.0114547394121293	0.0928683288500342
GO:0051059	NF-kappaB binding	13/4017	32/18639	0.40625	1.88501213592233	0.0114609381153745	0.0928683288500342
GO:0019210	kinase inhibitor activity	29/4017	90/18639	0.322222222222222	1.49512073686831	0.0121262572942839	0.0976675060389009
GO:0003697	single-stranded DNA binding	37/4017	121/18639	0.305785123966942	1.41885210993772	0.01262507880971	0.101076229751989
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	93/4017	349/18639	0.26647564469914	1.23645495184149	0.0129685795126104	0.103208278621191
GO:0000149	SNARE binding	33/4017	106/18639	0.311320754716981	1.44453760198402	0.0135295395907724	0.107035470016939
GO:0070006	metalloaminopeptidase activity	11/4017	26/18639	0.423076923076923	1.96308956167059	0.0138925447829267	0.109260778675135
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	37/4017	122/18639	0.30327868852459	1.40722217461037	0.0144452800290612	0.112943505256461
GO:0140463	chromatin-protein adaptor activity	19/4017	54/18639	0.351851851851852	1.63260310347689	0.0147992207957346	0.115038129092425
GO:0160215	deacylase activity	22/4017	65/18639	0.338461538461538	1.57047164933647	0.0149024010673973	0.115170579347458
GO:0140102	catalytic activity, acting on a rRNA	10/4017	23/18639	0.434782608695652	2.01740429262591	0.0151157934548365	0.116148366948944
GO:0017018	myosin phosphatase activity	27/4017	84/18639	0.321428571428571	1.49143817347701	0.0156417654946861	0.119483711248947
GO:0002039	p53 binding	23/4017	69/18639	0.333333333333333	1.54667662434653	0.0157285962451868	0.119483711248947
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	9/4017	20/18639	0.45	2.08801344286781	0.01623850892952	0.122660375360273
GO:0032404	mismatch repair complex binding	6/4017	11/18639	0.545454545454545	2.53092538529432	0.0168306887245396	0.12482558545362
GO:0048407	platelet-derived growth factor binding	6/4017	11/18639	0.545454545454545	2.53092538529432	0.0168306887245396	0.12482558545362
GO:0070566	adenylyltransferase activity	12/4017	30/18639	0.4	1.85601194921583	0.0170402877476888	0.12482558545362
GO:0004029	aldehyde dehydrogenase (NAD+) activity	8/4017	17/18639	0.470588235294118	2.18354346966569	0.0171076544540975	0.12482558545362
GO:0004549	tRNA-specific ribonuclease activity	8/4017	17/18639	0.470588235294118	2.18354346966569	0.0171076544540975	0.12482558545362
GO:0004659	prenyltransferase activity	8/4017	17/18639	0.470588235294118	2.18354346966569	0.0171076544540975	0.12482558545362
GO:0043130	ubiquitin binding	31/4017	100/18639	0.31	1.43840926064227	0.0173473743328917	0.12482558545362
GO:0008474	palmitoyl-(protein) hydrolase activity	7/4017	14/18639	0.5	2.32001493651979	0.0174587767238795	0.12482558545362
GO:0098599	palmitoyl hydrolase activity	7/4017	14/18639	0.5	2.32001493651979	0.0174587767238795	0.12482558545362
GO:1990825	sequence-specific mRNA binding	7/4017	14/18639	0.5	2.32001493651979	0.0174587767238795	0.12482558545362
GO:0016829	lyase activity	56/4017	200/18639	0.28	1.29920836445108	0.0181500763224221	0.129077936399353
GO:0008266	poly(U) RNA binding	11/4017	27/18639	0.407407407407407	1.89038254086798	0.0189685257683662	0.134184756361405
GO:0042578	phosphoric ester hydrolase activity	95/4017	363/18639	0.261707988980716	1.21433288688364	0.0196406671955206	0.138192463912618
GO:0008137	NADH dehydrogenase (ubiquinone) activity	15/4017	41/18639	0.365853658536585	1.69757190477058	0.0198451406665839	0.138192463912618
GO:0016877	ligase activity, forming carbon-sulfur bonds	15/4017	41/18639	0.365853658536585	1.69757190477058	0.0198451406665839	0.138192463912618
GO:0015078	proton transmembrane transporter activity	52/4017	185/18639	0.281081081081081	1.30422461296248	0.0206085549106135	0.142764963292696
GO:0004540	RNA nuclease activity	36/4017	121/18639	0.297520661157025	1.38050475561508	0.0210919178400906	0.145360279135058
GO:0046915	transition metal ion transmembrane transporter activity	16/4017	45/18639	0.355555555555556	1.64978839930296	0.021823674023201	0.14963206240523
GO:0001098	basal transcription machinery binding	20/4017	60/18639	0.333333333333333	1.54667662434653	0.0232818583841931	0.15800936375465
GO:0001099	basal RNA polymerase II transcription machinery binding	20/4017	60/18639	0.333333333333333	1.54667662434653	0.0232818583841931	0.15800936375465
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	36/4017	122/18639	0.295081967213115	1.36918914286414	0.023874231342382	0.161211350024064
GO:0140223	general transcription initiation factor activity	22/4017	68/18639	0.323529411764706	1.50118613539516	0.025337853220413	0.170234722390413
GO:0016229	steroid dehydrogenase activity	13/4017	35/18639	0.371428571428571	1.72343966712899	0.0256006560998742	0.171140386027659
GO:0016874	ligase activity	47/4017	167/18639	0.281437125748503	1.30587667085545	0.0260674747112507	0.173394097954936
GO:0003714	transcription corepressor activity	56/4017	204/18639	0.274509803921569	1.27373369063832	0.0265106410908243	0.175468946229862
GO:0004526	ribonuclease P activity	6/4017	12/18639	0.5	2.32001493651979	0.0276075539101089	0.17745817104719
GO:0016273	arginine N-methyltransferase activity	6/4017	12/18639	0.5	2.32001493651979	0.0276075539101089	0.17745817104719
GO:0016274	protein-arginine N-methyltransferase activity	6/4017	12/18639	0.5	2.32001493651979	0.0276075539101089	0.17745817104719
GO:0016423	tRNA (guanine) methyltransferase activity	6/4017	12/18639	0.5	2.32001493651979	0.0276075539101089	0.17745817104719
GO:0035251	UDP-glucosyltransferase activity	6/4017	12/18639	0.5	2.32001493651979	0.0276075539101089	0.17745817104719
GO:0043047	single-stranded telomeric DNA binding	6/4017	12/18639	0.5	2.32001493651979	0.0276075539101089	0.17745817104719
GO:0017056	structural constituent of nuclear pore	10/4017	25/18639	0.4	1.85601194921583	0.0284024192843929	0.181693945374322
GO:0016651	oxidoreductase activity, acting on NAD(P)H	27/4017	88/18639	0.306818181818182	1.42364552922805	0.028621128584683	0.182221185322482
GO:0019903	protein phosphatase binding	41/4017	144/18639	0.284722222222222	1.32111961662933	0.0299214601451447	0.189597119497907
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	38/4017	132/18639	0.287878787878788	1.335766175572	0.0302238990808658	0.190610155995837
GO:0044390	ubiquitin-like protein conjugating enzyme binding	13/4017	36/18639	0.361111111111111	1.67556634304207	0.0323738831903754	0.203210712795924
GO:0019902	phosphatase binding	52/4017	190/18639	0.273684210526316	1.26990291262136	0.0332243058973545	0.207574284975528
GO:0004177	aminopeptidase activity	14/4017	40/18639	0.35	1.62401045556385	0.0352245130283556	0.216642416212169
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	8/4017	19/18639	0.421052631578947	1.95369678864825	0.0353238943412513	0.216642416212169
GO:0005346	purine ribonucleotide transmembrane transporter activity	8/4017	19/18639	0.421052631578947	1.95369678864825	0.0353238943412513	0.216642416212169
GO:0046527	glucosyltransferase activity	8/4017	19/18639	0.421052631578947	1.95369678864825	0.0353238943412513	0.216642416212169
GO:0003684	damaged DNA binding	23/4017	74/18639	0.310810810810811	1.44217144702582	0.0356706006804293	0.217769831551297
GO:0008143	poly(A) binding	10/4017	26/18639	0.384615384615385	1.78462687424599	0.0374710908478093	0.22772203847055
GO:0022853	active monoatomic ion transmembrane transporter activity	34/4017	118/18639	0.288135593220339	1.33695776002835	0.0382198691293828	0.231221561203551
GO:0000062	fatty-acyl-CoA binding	7/4017	16/18639	0.4375	2.03001306945482	0.0388939605635805	0.233189351002274
GO:0015923	mannosidase activity	7/4017	16/18639	0.4375	2.03001306945482	0.0388939605635805	0.233189351002274
GO:0140693	molecular condensate scaffold activity	16/4017	48/18639	0.333333333333333	1.54667662434653	0.0397704559120791	0.237379908725222
GO:0140097	catalytic activity, acting on DNA	86/4017	336/18639	0.255952380952381	1.18762669369465	0.0418811146043296	0.246782406248937
GO:0035673	oligopeptide transmembrane transporter activity	6/4017	13/18639	0.461538461538462	2.14155224909519	0.0421039910223453	0.246782406248937
GO:0140666	annealing activity	6/4017	13/18639	0.461538461538462	2.14155224909519	0.0421039910223453	0.246782406248937
GO:0008187	poly-pyrimidine tract binding	11/4017	30/18639	0.366666666666667	1.70134428678118	0.0422686395145898	0.246782406248937
GO:0015215	nucleotide transmembrane transporter activity	11/4017	30/18639	0.366666666666667	1.70134428678118	0.0422686395145898	0.246782406248937
GO:0051020	GTPase binding	81/4017	315/18639	0.257142857142857	1.19315053878161	0.0427346066476603	0.247873091264142
GO:0005381	iron ion transmembrane transporter activity	5/4017	10/18639	0.5	2.32001493651979	0.0441240057747688	0.247873091264142
GO:0005522	profilin binding	5/4017	10/18639	0.5	2.32001493651979	0.0441240057747688	0.247873091264142
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	5/4017	10/18639	0.5	2.32001493651979	0.0441240057747688	0.247873091264142
GO:0015924	mannosyl-oligosaccharide mannosidase activity	5/4017	10/18639	0.5	2.32001493651979	0.0441240057747688	0.247873091264142
GO:0016783	sulfurtransferase activity	5/4017	10/18639	0.5	2.32001493651979	0.0441240057747688	0.247873091264142
GO:0016868	intramolecular phosphotransferase activity	5/4017	10/18639	0.5	2.32001493651979	0.0441240057747688	0.247873091264142
GO:0030957	Tat protein binding	5/4017	10/18639	0.5	2.32001493651979	0.0441240057747688	0.247873091264142
GO:0097177	mitochondrial ribosome binding	5/4017	10/18639	0.5	2.32001493651979	0.0441240057747688	0.247873091264142
GO:0016004	phospholipase activator activity	8/4017	20/18639	0.4	1.85601194921583	0.0480474846157388	0.264961359448412
GO:0061608	nuclear import signal receptor activity	8/4017	20/18639	0.4	1.85601194921583	0.0480474846157388	0.264961359448412
GO:0001671	ATPase activator activity	10/4017	27/18639	0.37037037037037	1.71852958260725	0.0483549526592465	0.264961359448412
GO:0004364	glutathione transferase activity	10/4017	27/18639	0.37037037037037	1.71852958260725	0.0483549526592465	0.264961359448412
GO:0005385	zinc ion transmembrane transporter activity	10/4017	27/18639	0.37037037037037	1.71852958260725	0.0483549526592465	0.264961359448412
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	10/4017	27/18639	0.37037037037037	1.71852958260725	0.0483549526592465	0.264961359448412
GO:0034212	protein N-acetyltransferase activity	17/4017	53/18639	0.320754716981132	1.48831146871081	0.0492859397311126	0.268960413961215
GO:0016887	ATP hydrolysis activity	104/4017	417/18639	0.249400479616307	1.15722567577006	0.0521023216429044	0.283174000148631
GO:0008234	cysteine-type peptidase activity	50/4017	187/18639	0.267379679144385	1.24064969867369	0.0526847952561387	0.28518045043505
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	7/4017	17/18639	0.411764705882353	1.91060053595747	0.0541443748402186	0.288410474746503
GO:0048038	quinone binding	7/4017	17/18639	0.411764705882353	1.91060053595747	0.0541443748402186	0.288410474746503
GO:0070403	NAD+ binding	7/4017	17/18639	0.411764705882353	1.91060053595747	0.0541443748402186	0.288410474746503
GO:1901567	fatty acid derivative binding	7/4017	17/18639	0.411764705882353	1.91060053595747	0.0541443748402186	0.288410474746503
GO:0030291	protein serine/threonine kinase inhibitor activity	15/4017	46/18639	0.326086956521739	1.51305321946943	0.0546294294309652	0.289839472814288
GO:0048027	mRNA 5'-UTR binding	9/4017	24/18639	0.375	1.74001120238984	0.0553571901397116	0.291388044160608
GO:0060229	lipase activator activity	9/4017	24/18639	0.375	1.74001120238984	0.0553571901397116	0.291388044160608
GO:0015605	organophosphate ester transmembrane transporter activity	16/4017	50/18639	0.32	1.48480955937267	0.0564810960352124	0.296138138819918
GO:0016776	phosphotransferase activity, phosphate group as acceptor	13/4017	39/18639	0.333333333333333	1.54667662434653	0.0602280922728129	0.312764573879004
GO:0005347	ATP transmembrane transporter activity	6/4017	14/18639	0.428571428571429	1.98858423130268	0.0605879017461945	0.312764573879004
GO:0008174	mRNA methyltransferase activity	6/4017	14/18639	0.428571428571429	1.98858423130268	0.0605879017461945	0.312764573879004
GO:0098847	sequence-specific single stranded DNA binding	6/4017	14/18639	0.428571428571429	1.98858423130268	0.0605879017461945	0.312764573879004
GO:0097718	disordered domain specific binding	10/4017	28/18639	0.357142857142857	1.65715352608556	0.0611659457085727	0.314278977334722
GO:0016278	lysine N-methyltransferase activity	21/4017	70/18639	0.3	1.39200896191187	0.0613513934811986	0.314278977334722
GO:0048029	monosaccharide binding	22/4017	74/18639	0.297297297297297	1.37946834063339	0.0617095134869883	0.31490694477902
GO:0050660	flavin adenine dinucleotide binding	25/4017	86/18639	0.290697674418605	1.34884589332546	0.0619976490532452	0.315174360396155
GO:0004712	protein serine/threonine/tyrosine kinase activity	14/4017	43/18639	0.325581395348837	1.51070740052452	0.0627773727183531	0.316327455565817
GO:0045296	cadherin binding	84/4017	334/18639	0.251497005988024	1.16695362076445	0.0628707825490524	0.316327455565817
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	8/4017	21/18639	0.380952380952381	1.7676304278246	0.0634074480864913	0.316327455565817
GO:0009931	calcium-dependent protein serine/threonine kinase activity	8/4017	21/18639	0.380952380952381	1.7676304278246	0.0634074480864913	0.316327455565817
GO:1904047	S-adenosyl-L-methionine binding	8/4017	21/18639	0.380952380952381	1.7676304278246	0.0634074480864913	0.316327455565817
GO:0019783	ubiquitin-like protein peptidase activity	35/4017	127/18639	0.275590551181102	1.27874839020776	0.0642741314272707	0.319459158803944
GO:0043495	protein-membrane adaptor activity	15/4017	47/18639	0.319148936170213	1.48086059777859	0.0648146832958957	0.319768382164622
GO:0061733	protein-lysine-acetyltransferase activity	15/4017	47/18639	0.319148936170213	1.48086059777859	0.0648146832958957	0.319768382164622
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	11/4017	32/18639	0.34375	1.59501026885736	0.0657704147763332	0.321593884176245
GO:0140030	modification-dependent protein binding	46/4017	173/18639	0.265895953757225	1.23376516855388	0.0660211168585008	0.321593884176245
GO:0019209	kinase activator activity	40/4017	148/18639	0.27027027027027	1.25406212784854	0.0662191702418095	0.321593884176245
GO:0019107	myristoyltransferase activity	5/4017	11/18639	0.454545454545455	2.10910448774526	0.0668684366499598	0.321593884176245
GO:0019206	nucleoside kinase activity	5/4017	11/18639	0.454545454545455	2.10910448774526	0.0668684366499598	0.321593884176245
GO:0032050	clathrin heavy chain binding	5/4017	11/18639	0.454545454545455	2.10910448774526	0.0668684366499598	0.321593884176245
GO:0070990	snRNP binding	5/4017	11/18639	0.454545454545455	2.10910448774526	0.0668684366499598	0.321593884176245
GO:0055106	ubiquitin-protein transferase regulator activity	12/4017	36/18639	0.333333333333333	1.54667662434653	0.069408468319299	0.33198674497596
GO:0003725	double-stranded RNA binding	22/4017	75/18639	0.293333333333333	1.36107542942494	0.0701922163931611	0.33198674497596
GO:0008139	nuclear localization sequence binding	9/4017	25/18639	0.36	1.67041075429425	0.0705192487458284	0.33198674497596
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	9/4017	25/18639	0.36	1.67041075429425	0.0705192487458284	0.33198674497596
GO:0017025	TBP-class protein binding	9/4017	25/18639	0.36	1.67041075429425	0.0705192487458284	0.33198674497596
GO:0047617	fatty acyl-CoA hydrolase activity	9/4017	25/18639	0.36	1.67041075429425	0.0705192487458284	0.33198674497596
GO:0008409	5'-3' exonuclease activity	7/4017	18/18639	0.388888888888889	1.80445606173762	0.072637964572666	0.337211661922411
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	7/4017	18/18639	0.388888888888889	1.80445606173762	0.072637964572666	0.337211661922411
GO:0070064	proline-rich region binding	7/4017	18/18639	0.388888888888889	1.80445606173762	0.072637964572666	0.337211661922411
GO:1990381	ubiquitin-specific protease binding	7/4017	18/18639	0.388888888888889	1.80445606173762	0.072637964572666	0.337211661922411
GO:0001046	core promoter sequence-specific DNA binding	14/4017	44/18639	0.318181818181818	1.47637314142169	0.0744918133063552	0.343432946174472
GO:0043014	alpha-tubulin binding	14/4017	44/18639	0.318181818181818	1.47637314142169	0.0744918133063552	0.343432946174472
GO:0004721	phosphoprotein phosphatase activity	46/4017	175/18639	0.262857142857143	1.21966499519898	0.0775331014820993	0.356225967977893
GO:0016758	hexosyltransferase activity	51/4017	197/18639	0.258883248730964	1.20122600774121	0.0826600787825881	0.37430860436775
GO:0004559	alpha-mannosidase activity	6/4017	15/18639	0.4	1.85601194921583	0.0831485830196124	0.37430860436775
GO:0031386	protein tag activity	6/4017	15/18639	0.4	1.85601194921583	0.0831485830196124	0.37430860436775
GO:0050780	dopamine receptor binding	6/4017	15/18639	0.4	1.85601194921583	0.0831485830196124	0.37430860436775
GO:0061578	K63-linked deubiquitinase activity	6/4017	15/18639	0.4	1.85601194921583	0.0831485830196124	0.37430860436775
GO:0141047	molecular tag activity	6/4017	15/18639	0.4	1.85601194921583	0.0831485830196124	0.37430860436775
GO:0008094	ATP-dependent activity, acting on DNA	54/4017	210/18639	0.257142857142857	1.19315053878161	0.0840903480742595	0.377277836829815
GO:0004529	DNA exonuclease activity	9/4017	26/18639	0.346153846153846	1.60616418682139	0.0880153323388971	0.388170691934055
GO:0008198	ferrous iron binding	9/4017	26/18639	0.346153846153846	1.60616418682139	0.0880153323388971	0.388170691934055
GO:0015216	purine nucleotide transmembrane transporter activity	9/4017	26/18639	0.346153846153846	1.60616418682139	0.0880153323388971	0.388170691934055
GO:0016289	acyl-CoA hydrolase activity	9/4017	26/18639	0.346153846153846	1.60616418682139	0.0880153323388971	0.388170691934055
GO:0034237	protein kinase A regulatory subunit binding	9/4017	26/18639	0.346153846153846	1.60616418682139	0.0880153323388971	0.388170691934055
GO:0140713	histone chaperone activity	43/4017	164/18639	0.26219512195122	1.21659319841891	0.088260202204901	0.388170691934055
GO:1901505	carbohydrate derivative transmembrane transporter activity	16/4017	53/18639	0.30188679245283	1.40076373525723	0.0896690407285394	0.393073794931335
GO:0016279	protein-lysine N-methyltransferase activity	20/4017	69/18639	0.289855072463768	1.34493619508394	0.090272204031503	0.3938497314084
GO:0016836	hydro-lyase activity	18/4017	61/18639	0.295081967213115	1.36918914286414	0.090435203846207	0.3938497314084
GO:0031624	ubiquitin conjugating enzyme binding	10/4017	30/18639	0.333333333333333	1.54667662434653	0.0928364686807064	0.399047933388534
GO:0051721	protein phosphatase 2A binding	10/4017	30/18639	0.333333333333333	1.54667662434653	0.0928364686807064	0.399047933388534
GO:0140674	ATP-dependent histone chaperone activity	40/4017	152/18639	0.263157894736842	1.22106049290515	0.0929476545164519	0.399047933388534
GO:0008238	exopeptidase activity	28/4017	102/18639	0.274509803921569	1.27373369063832	0.0938217830328192	0.399047933388534
GO:0003995	acyl-CoA dehydrogenase activity	5/4017	12/18639	0.416666666666667	1.93334578043316	0.0949119243212819	0.399047933388534
GO:0004859	phospholipase inhibitor activity	5/4017	12/18639	0.416666666666667	1.93334578043316	0.0949119243212819	0.399047933388534
GO:0031543	peptidyl-proline dioxygenase activity	5/4017	12/18639	0.416666666666667	1.93334578043316	0.0949119243212819	0.399047933388534
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	5/4017	12/18639	0.416666666666667	1.93334578043316	0.0949119243212819	0.399047933388534
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	5/4017	12/18639	0.416666666666667	1.93334578043316	0.0949119243212819	0.399047933388534
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	5/4017	12/18639	0.416666666666667	1.93334578043316	0.0949119243212819	0.399047933388534
GO:1990247	N6-methyladenosine-containing RNA reader activity	5/4017	12/18639	0.416666666666667	1.93334578043316	0.0949119243212819	0.399047933388534
GO:0052866	phosphatidylinositol phosphate phosphatase activity	11/4017	34/18639	0.323529411764706	1.50118613539516	0.0963755770390705	0.403931493734286
GO:0004402	histone acetyltransferase activity	13/4017	42/18639	0.30952380952381	1.43619972260749	0.100735066856974	0.419572537033564
GO:0048487	beta-tubulin binding	13/4017	42/18639	0.30952380952381	1.43619972260749	0.100735066856974	0.419572537033564
GO:0000295	adenine nucleotide transmembrane transporter activity	8/4017	23/18639	0.347826086956522	1.61392343410072	0.102291873926668	0.423418685572616
GO:0008171	O-methyltransferase activity	8/4017	23/18639	0.347826086956522	1.61392343410072	0.102291873926668	0.423418685572616
GO:0003713	transcription coactivator activity	64/4017	256/18639	0.25	1.1600074682599	0.102613259423972	0.423438048919292
GO:0050661	NADP binding	16/4017	54/18639	0.296296296296296	1.3748236660858	0.103012134920489	0.423776075042133
GO:0016922	nuclear receptor binding	36/4017	137/18639	0.262773722627737	1.21927792284252	0.108075824605996	0.443113938463597
GO:0005506	iron ion binding	40/4017	154/18639	0.25974025974026	1.20520256442587	0.10871926012923	0.443113938463597
GO:0031267	small GTPase binding	70/4017	283/18639	0.247349823321555	1.14771056930308	0.108753828418092	0.443113938463597
GO:0004708	MAP kinase kinase activity	6/4017	16/18639	0.375	1.74001120238984	0.109701356493232	0.443113938463597
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	6/4017	16/18639	0.375	1.74001120238984	0.109701356493232	0.443113938463597
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	6/4017	16/18639	0.375	1.74001120238984	0.109701356493232	0.443113938463597
GO:0017147	Wnt-protein binding	10/4017	31/18639	0.32258064516129	1.49678383001277	0.111731356752879	0.448603075010808
GO:0072349	modified amino acid transmembrane transporter activity	10/4017	31/18639	0.32258064516129	1.49678383001277	0.111731356752879	0.448603075010808
GO:0042054	histone methyltransferase activity	19/4017	67/18639	0.283582089552239	1.31582936698137	0.115344930077296	0.461725064411211
GO:0016408	C-acyltransferase activity	7/4017	20/18639	0.35	1.62401045556385	0.119365978346896	0.46847635213545
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	7/4017	20/18639	0.35	1.62401045556385	0.119365978346896	0.46847635213545
GO:0030742	GTP-dependent protein binding	7/4017	20/18639	0.35	1.62401045556385	0.119365978346896	0.46847635213545
GO:0000510	H3-H4 histone complex chaperone activity	39/4017	151/18639	0.258278145695364	1.19841831157976	0.119484245383836	0.46847635213545
GO:0140584	chromatin extrusion motor activity	39/4017	151/18639	0.258278145695364	1.19841831157976	0.119484245383836	0.46847635213545
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	39/4017	151/18639	0.258278145695364	1.19841831157976	0.119484245383836	0.46847635213545
GO:0140849	ATP-dependent H2AZ histone chaperone activity	39/4017	151/18639	0.258278145695364	1.19841831157976	0.119484245383836	0.46847635213545
GO:0004197	cysteine-type endopeptidase activity	24/4017	88/18639	0.272727272727273	1.26546269264716	0.120817056192731	0.472316971139421
GO:0051117	ATPase binding	23/4017	84/18639	0.273809523809524	1.27048436999893	0.122585805328184	0.477834465667001
GO:0035035	histone acetyltransferase binding	8/4017	24/18639	0.333333333333333	1.54667662434653	0.125759215820146	0.484553520321429
GO:0042625	ATPase-coupled ion transmembrane transporter activity	8/4017	24/18639	0.333333333333333	1.54667662434653	0.125759215820146	0.484553520321429
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	8/4017	24/18639	0.333333333333333	1.54667662434653	0.125759215820146	0.484553520321429
GO:0046961	proton-transporting ATPase activity, rotational mechanism	8/4017	24/18639	0.333333333333333	1.54667662434653	0.125759215820146	0.484553520321429
GO:0005518	collagen binding	20/4017	72/18639	0.277777777777778	1.28889718695544	0.127651669458795	0.487250347807629
GO:0004535	poly(A)-specific ribonuclease activity	5/4017	13/18639	0.384615384615385	1.78462687424599	0.127916882633117	0.487250347807629
GO:0008417	fucosyltransferase activity	5/4017	13/18639	0.384615384615385	1.78462687424599	0.127916882633117	0.487250347807629
GO:0031994	insulin-like growth factor I binding	5/4017	13/18639	0.384615384615385	1.78462687424599	0.127916882633117	0.487250347807629
GO:0015616	DNA translocase activity	39/4017	152/18639	0.256578947368421	1.19053398058252	0.128642891789393	0.488623711143233
GO:0032934	sterol binding	19/4017	68/18639	0.279411764705882	1.296478935114	0.129209024029847	0.489383753903413
GO:0019789	SUMO transferase activity	9/4017	28/18639	0.321428571428571	1.49143817347701	0.129956900506688	0.490825920840232
GO:0071949	FAD binding	12/4017	40/18639	0.3	1.39200896191187	0.134940548994252	0.504498369615417
GO:0001223	transcription coactivator binding	13/4017	44/18639	0.295454545454545	1.37091791703442	0.135086324848406	0.504498369615417
GO:0019205	nucleobase-containing compound kinase activity	13/4017	44/18639	0.295454545454545	1.37091791703442	0.135086324848406	0.504498369615417
GO:0030020	extracellular matrix structural constituent conferring tensile strength	13/4017	44/18639	0.295454545454545	1.37091791703442	0.135086324848406	0.504498369615417
GO:0061775	cohesin loader activity	39/4017	153/18639	0.254901960784314	1.18275271273558	0.138226765192197	0.51004606310786
GO:0002020	protease binding	35/4017	136/18639	0.257352941176471	1.19412533497342	0.139257927481808	0.51004606310786
GO:0140789	histone phosphatase activity	35/4017	136/18639	0.257352941176471	1.19412533497342	0.139257927481808	0.51004606310786
GO:0003724	RNA helicase activity	21/4017	77/18639	0.272727272727273	1.26546269264716	0.139723701234347	0.51004606310786
GO:0004550	nucleoside diphosphate kinase activity	6/4017	17/18639	0.352941176470588	1.63765760224926	0.140005164667602	0.51004606310786
GO:0016018	cyclosporin A binding	6/4017	17/18639	0.352941176470588	1.63765760224926	0.140005164667602	0.51004606310786
GO:0016805	dipeptidase activity	6/4017	17/18639	0.352941176470588	1.63765760224926	0.140005164667602	0.51004606310786
GO:0017110	nucleoside diphosphate phosphatase activity	6/4017	17/18639	0.352941176470588	1.63765760224926	0.140005164667602	0.51004606310786
GO:0031489	myosin V binding	6/4017	17/18639	0.352941176470588	1.63765760224926	0.140005164667602	0.51004606310786
GO:0101005	deubiquitinase activity	30/4017	115/18639	0.260869565217391	1.21044257557554	0.142185174637013	0.516580376330669
GO:0140658	ATP-dependent chromatin remodeler activity	40/4017	158/18639	0.253164556962025	1.17469110709863	0.145216911872913	0.523975761978141
GO:0005123	death receptor binding	7/4017	21/18639	0.333333333333333	1.54667662434653	0.147345243477099	0.523975761978141
GO:0035613	RNA stem-loop binding	7/4017	21/18639	0.333333333333333	1.54667662434653	0.147345243477099	0.523975761978141
GO:0005528	FK506 binding	4/4017	10/18639	0.4	1.85601194921583	0.149707360565183	0.523975761978141
GO:0008239	dipeptidyl-peptidase activity	4/4017	10/18639	0.4	1.85601194921583	0.149707360565183	0.523975761978141
GO:0015279	store-operated calcium channel activity	4/4017	10/18639	0.4	1.85601194921583	0.149707360565183	0.523975761978141
GO:0031996	thioesterase binding	4/4017	10/18639	0.4	1.85601194921583	0.149707360565183	0.523975761978141
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	4/4017	10/18639	0.4	1.85601194921583	0.149707360565183	0.523975761978141
GO:0043295	glutathione binding	4/4017	10/18639	0.4	1.85601194921583	0.149707360565183	0.523975761978141
GO:0043422	protein kinase B binding	4/4017	10/18639	0.4	1.85601194921583	0.149707360565183	0.523975761978141
GO:0070513	death domain binding	4/4017	10/18639	0.4	1.85601194921583	0.149707360565183	0.523975761978141
GO:0098505	G-rich strand telomeric DNA binding	4/4017	10/18639	0.4	1.85601194921583	0.149707360565183	0.523975761978141
GO:1905394	retromer complex binding	4/4017	10/18639	0.4	1.85601194921583	0.149707360565183	0.523975761978141
GO:1990757	ubiquitin ligase activator activity	4/4017	10/18639	0.4	1.85601194921583	0.149707360565183	0.523975761978141
GO:0008483	transaminase activity	8/4017	25/18639	0.32	1.48480955937267	0.151754494443355	0.528374372580118
GO:0019211	phosphatase activator activity	8/4017	25/18639	0.32	1.48480955937267	0.151754494443355	0.528374372580118
GO:0016417	S-acyltransferase activity	9/4017	29/18639	0.310344827586207	1.44000927094332	0.154246269203297	0.535630992111837
GO:0140311	protein sequestering activity	10/4017	33/18639	0.303030303030303	1.40606965849684	0.155429521667085	0.535630992111837
GO:0140416	transcription regulator inhibitor activity	10/4017	33/18639	0.303030303030303	1.40606965849684	0.155429521667085	0.535630992111837
GO:0019213	deacetylase activity	11/4017	37/18639	0.297297297297297	1.37946834063339	0.155691591792477	0.535630992111837
GO:1901981	phosphatidylinositol phosphate binding	46/4017	185/18639	0.248648648648649	1.15373715762065	0.155841777061709	0.535630992111837
GO:0016782	transferase activity, transferring sulphur-containing groups	19/4017	70/18639	0.271428571428571	1.25943667982503	0.159713354064007	0.547530139445069
GO:0008235	metalloexopeptidase activity	18/4017	66/18639	0.272727272727273	1.26546269264716	0.162433992236313	0.555432858363044
GO:0004705	JUN kinase activity	5/4017	14/18639	0.357142857142857	1.65715352608556	0.165321872014741	0.559583146541034
GO:0005161	platelet-derived growth factor receptor binding	5/4017	14/18639	0.357142857142857	1.65715352608556	0.165321872014741	0.559583146541034
GO:0030983	mismatched DNA binding	5/4017	14/18639	0.357142857142857	1.65715352608556	0.165321872014741	0.559583146541034
GO:0042813	Wnt receptor activity	5/4017	14/18639	0.357142857142857	1.65715352608556	0.165321872014741	0.559583146541034
GO:0003689	DNA clamp loader activity	40/4017	160/18639	0.25	1.1600074682599	0.165929178939285	0.56022048545915
GO:0008186	ATP-dependent activity, acting on RNA	21/4017	79/18639	0.265822784810127	1.23342566245356	0.169587499553125	0.569694690709871
GO:0016835	carbon-oxygen lyase activity	21/4017	79/18639	0.265822784810127	1.23342566245356	0.169587499553125	0.569694690709871
GO:0017069	snRNA binding	15/4017	54/18639	0.277777777777778	1.28889718695544	0.170338516777963	0.570569725857615
GO:0030295	protein kinase activator activity	35/4017	139/18639	0.251798561151079	1.16835284572939	0.17275674202235	0.570569725857615
GO:0032813	tumor necrosis factor receptor superfamily binding	14/4017	50/18639	0.28	1.29920836445108	0.172788572140801	0.570569725857615
GO:0000400	four-way junction DNA binding	6/4017	18/18639	0.333333333333333	1.54667662434653	0.173688764715071	0.570569725857615
GO:0016854	racemase and epimerase activity	6/4017	18/18639	0.333333333333333	1.54667662434653	0.173688764715071	0.570569725857615
GO:0017128	phospholipid scramblase activity	6/4017	18/18639	0.333333333333333	1.54667662434653	0.173688764715071	0.570569725857615
GO:0031690	adrenergic receptor binding	6/4017	18/18639	0.333333333333333	1.54667662434653	0.173688764715071	0.570569725857615
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	6/4017	18/18639	0.333333333333333	1.54667662434653	0.173688764715071	0.570569725857615
GO:0070628	proteasome binding	6/4017	18/18639	0.333333333333333	1.54667662434653	0.173688764715071	0.570569725857615
GO:0052689	carboxylic ester hydrolase activity	24/4017	92/18639	0.260869565217391	1.21044257557554	0.174344089955297	0.571318745760373
GO:0051879	Hsp90 protein binding	12/4017	42/18639	0.285714285714286	1.32572282086845	0.17711201311288	0.578970077095161
GO:0061133	endopeptidase activator activity	7/4017	22/18639	0.318181818181818	1.47637314142169	0.178079454833356	0.580712758810238
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	10/4017	34/18639	0.294117647058824	1.36471466854105	0.180035331928758	0.585662381481143
GO:0016769	transferase activity, transferring nitrogenous groups	9/4017	30/18639	0.3	1.39200896191187	0.180564755141551	0.58595892627246
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	16/4017	59/18639	0.271186440677966	1.25831318590904	0.186668602594226	0.602840390503575
GO:0031593	polyubiquitin modification-dependent protein binding	16/4017	59/18639	0.271186440677966	1.25831318590904	0.186668602594226	0.602840390503575
GO:0140034	methylation-dependent protein binding	20/4017	76/18639	0.263157894736842	1.22106049290515	0.189674757993252	0.611072654065007
GO:0008237	metallopeptidase activity	45/4017	184/18639	0.244565217391304	1.13478991460207	0.19020412986923	0.61130510008452
GO:0030544	Hsp70 protein binding	14/4017	51/18639	0.274509803921569	1.27373369063832	0.193608002448961	0.613246540805282
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	4/4017	11/18639	0.363636363636364	1.68728359019621	0.19704388851674	0.613246540805282
GO:0010854	adenylate cyclase regulator activity	4/4017	11/18639	0.363636363636364	1.68728359019621	0.19704388851674	0.613246540805282
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	4/4017	11/18639	0.363636363636364	1.68728359019621	0.19704388851674	0.613246540805282
GO:0015217	ADP transmembrane transporter activity	4/4017	11/18639	0.363636363636364	1.68728359019621	0.19704388851674	0.613246540805282
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	4/4017	11/18639	0.363636363636364	1.68728359019621	0.19704388851674	0.613246540805282
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	4/4017	11/18639	0.363636363636364	1.68728359019621	0.19704388851674	0.613246540805282
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	4/4017	11/18639	0.363636363636364	1.68728359019621	0.19704388851674	0.613246540805282
GO:0019215	intermediate filament binding	4/4017	11/18639	0.363636363636364	1.68728359019621	0.19704388851674	0.613246540805282
GO:0034511	U3 snoRNA binding	4/4017	11/18639	0.363636363636364	1.68728359019621	0.19704388851674	0.613246540805282
GO:0043522	leucine zipper domain binding	4/4017	11/18639	0.363636363636364	1.68728359019621	0.19704388851674	0.613246540805282
GO:0180030	inositol phosphate kinase activity	4/4017	11/18639	0.363636363636364	1.68728359019621	0.19704388851674	0.613246540805282
GO:1900750	oligopeptide binding	4/4017	11/18639	0.363636363636364	1.68728359019621	0.19704388851674	0.613246540805282
GO:0001221	transcription coregulator binding	29/4017	115/18639	0.252173913043478	1.17009448972302	0.197229627932888	0.613246540805282
GO:1990841	promoter-specific chromatin binding	18/4017	68/18639	0.264705882352941	1.22824320168695	0.197920291844778	0.613966195351435
GO:0010485	histone H4 acetyltransferase activity	10/4017	35/18639	0.285714285714286	1.32572282086845	0.206292039305908	0.629062596894214
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	5/4017	15/18639	0.333333333333333	1.54667662434653	0.206408516512305	0.629062596894214
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	5/4017	15/18639	0.333333333333333	1.54667662434653	0.206408516512305	0.629062596894214
GO:0015929	hexosaminidase activity	5/4017	15/18639	0.333333333333333	1.54667662434653	0.206408516512305	0.629062596894214
GO:0016846	carbon-sulfur lyase activity	5/4017	15/18639	0.333333333333333	1.54667662434653	0.206408516512305	0.629062596894214
GO:0031005	filamin binding	5/4017	15/18639	0.333333333333333	1.54667662434653	0.206408516512305	0.629062596894214
GO:0140776	protein-containing complex destabilizing activity	5/4017	15/18639	0.333333333333333	1.54667662434653	0.206408516512305	0.629062596894214
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	16/4017	60/18639	0.266666666666667	1.23734129947722	0.206550845203112	0.629062596894214
GO:0005164	tumor necrosis factor receptor binding	9/4017	31/18639	0.290322580645161	1.34710544701149	0.208723872664189	0.630408993791972
GO:0005520	insulin-like growth factor binding	6/4017	19/18639	0.315789473684211	1.46527259148618	0.210281499718492	0.630408993791972
GO:0042577	lipid phosphatase activity	6/4017	19/18639	0.315789473684211	1.46527259148618	0.210281499718492	0.630408993791972
GO:0070003	threonine-type peptidase activity	6/4017	19/18639	0.315789473684211	1.46527259148618	0.210281499718492	0.630408993791972
GO:0097001	ceramide binding	6/4017	19/18639	0.315789473684211	1.46527259148618	0.210281499718492	0.630408993791972
GO:0004022	alcohol dehydrogenase (NAD+) activity	7/4017	23/18639	0.304347826086957	1.41218300483813	0.211236521480032	0.630408993791972
GO:0004602	glutathione peroxidase activity	7/4017	23/18639	0.304347826086957	1.41218300483813	0.211236521480032	0.630408993791972
GO:0042171	lysophosphatidic acid acyltransferase activity	7/4017	23/18639	0.304347826086957	1.41218300483813	0.211236521480032	0.630408993791972
GO:0071617	lysophospholipid acyltransferase activity	7/4017	23/18639	0.304347826086957	1.41218300483813	0.211236521480032	0.630408993791972
GO:0004521	RNA endonuclease activity	19/4017	73/18639	0.26027397260274	1.2076790080514	0.21199723993222	0.63127017770463
GO:0016209	antioxidant activity	22/4017	86/18639	0.255813953488372	1.1869843861264	0.214965523009755	0.638686453920093
GO:0005080	protein kinase C binding	14/4017	52/18639	0.269230769230769	1.2492388119722	0.215532476845671	0.63895104554914
GO:0032266	phosphatidylinositol-3-phosphate binding	13/4017	48/18639	0.270833333333333	1.25667475728155	0.220128955333281	0.651133657700434
GO:0016248	channel inhibitor activity	12/4017	44/18639	0.272727272727273	1.26546269264716	0.224769133313067	0.663391459690002
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	32/4017	130/18639	0.246153846153846	1.14216119951744	0.225305535305413	0.663509913443473
GO:0019905	syntaxin binding	16/4017	61/18639	0.262295081967213	1.21705701587923	0.227351629798791	0.668064019870292
GO:0035064	methylated histone binding	19/4017	74/18639	0.256756756756757	1.19135902145611	0.23100238509462	0.677303045770848
GO:0004601	peroxidase activity	15/4017	57/18639	0.263157894736842	1.22106049290515	0.232817369901919	0.679643719560843
GO:0015932	nucleobase-containing compound transmembrane transporter activity	15/4017	57/18639	0.263157894736842	1.22106049290515	0.232817369901919	0.679643719560843
GO:0097110	scaffold protein binding	18/4017	70/18639	0.257142857142857	1.19315053878161	0.236761625522891	0.680365376399479
GO:0051018	protein kinase A binding	14/4017	53/18639	0.264150943396226	1.22566826835008	0.238469406570865	0.680365376399479
GO:0031369	translation initiation factor binding	9/4017	32/18639	0.28125	1.30500840179238	0.238502594744328	0.680365376399479
GO:0036408	histone H3K14 acetyltransferase activity	8/4017	28/18639	0.285714285714286	1.32572282086845	0.242715553740062	0.680365376399479
GO:0046625	sphingolipid binding	8/4017	28/18639	0.285714285714286	1.32572282086845	0.242715553740062	0.680365376399479
GO:0046966	nuclear thyroid hormone receptor binding	8/4017	28/18639	0.285714285714286	1.32572282086845	0.242715553740062	0.680365376399479
GO:0050698	proteoglycan sulfotransferase activity	8/4017	28/18639	0.285714285714286	1.32572282086845	0.242715553740062	0.680365376399479
GO:0051019	mitogen-activated protein kinase binding	8/4017	28/18639	0.285714285714286	1.32572282086845	0.242715553740062	0.680365376399479
GO:0001222	transcription corepressor binding	13/4017	49/18639	0.26530612244898	1.23102833366356	0.244314338524118	0.680365376399479
GO:0004622	lysophospholipase activity	7/4017	24/18639	0.291666666666667	1.35334204630321	0.246433059104692	0.680365376399479
GO:0005540	hyaluronic acid binding	7/4017	24/18639	0.291666666666667	1.35334204630321	0.246433059104692	0.680365376399479
GO:0015295	solute:proton symporter activity	7/4017	24/18639	0.291666666666667	1.35334204630321	0.246433059104692	0.680365376399479
GO:0140612	DNA damage sensor activity	7/4017	24/18639	0.291666666666667	1.35334204630321	0.246433059104692	0.680365376399479
GO:0000340	RNA 7-methylguanosine cap binding	4/4017	12/18639	0.333333333333333	1.54667662434653	0.248109870614469	0.680365376399479
GO:0000995	RNA polymerase III general transcription initiation factor activity	4/4017	12/18639	0.333333333333333	1.54667662434653	0.248109870614469	0.680365376399479
GO:0005527	macrolide binding	4/4017	12/18639	0.333333333333333	1.54667662434653	0.248109870614469	0.680365376399479
GO:0035197	siRNA binding	4/4017	12/18639	0.333333333333333	1.54667662434653	0.248109870614469	0.680365376399479
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	4/4017	12/18639	0.333333333333333	1.54667662434653	0.248109870614469	0.680365376399479
GO:1990459	transferrin receptor binding	4/4017	12/18639	0.333333333333333	1.54667662434653	0.248109870614469	0.680365376399479
GO:1990817	poly(A) RNA polymerase activity	4/4017	12/18639	0.333333333333333	1.54667662434653	0.248109870614469	0.680365376399479
GO:0000339	RNA cap binding	6/4017	20/18639	0.3	1.39200896191187	0.249245294592033	0.680365376399479
GO:0015095	magnesium ion transmembrane transporter activity	6/4017	20/18639	0.3	1.39200896191187	0.249245294592033	0.680365376399479
GO:0031418	L-ascorbic acid binding	6/4017	20/18639	0.3	1.39200896191187	0.249245294592033	0.680365376399479
GO:0052745	inositol phosphate phosphatase activity	6/4017	20/18639	0.3	1.39200896191187	0.249245294592033	0.680365376399479
GO:0140664	ATP-dependent DNA damage sensor activity	6/4017	20/18639	0.3	1.39200896191187	0.249245294592033	0.680365376399479
GO:0140939	histone H4 methyltransferase activity	6/4017	20/18639	0.3	1.39200896191187	0.249245294592033	0.680365376399479
GO:0141110	transporter inhibitor activity	12/4017	45/18639	0.266666666666667	1.23734129947722	0.250357090496072	0.680365376399479
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/4017	16/18639	0.3125	1.45000933532487	0.250366316520975	0.680365376399479
GO:0004707	MAP kinase activity	5/4017	16/18639	0.3125	1.45000933532487	0.250366316520975	0.680365376399479
GO:0005149	interleukin-1 receptor binding	5/4017	16/18639	0.3125	1.45000933532487	0.250366316520975	0.680365376399479
GO:0008142	oxysterol binding	5/4017	16/18639	0.3125	1.45000933532487	0.250366316520975	0.680365376399479
GO:0008296	3'-5'-DNA exonuclease activity	5/4017	16/18639	0.3125	1.45000933532487	0.250366316520975	0.680365376399479
GO:0017070	U6 snRNA binding	5/4017	16/18639	0.3125	1.45000933532487	0.250366316520975	0.680365376399479
GO:0055102	lipase inhibitor activity	5/4017	16/18639	0.3125	1.45000933532487	0.250366316520975	0.680365376399479
GO:0004812	aminoacyl-tRNA ligase activity	11/4017	41/18639	0.268292682926829	1.24488606349842	0.256599382042784	0.694480513747373
GO:0016875	ligase activity, forming carbon-oxygen bonds	11/4017	41/18639	0.268292682926829	1.24488606349842	0.256599382042784	0.694480513747373
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	17/4017	67/18639	0.253731343283582	1.17732101256228	0.26418018413443	0.713553345833805
GO:0071889	14-3-3 protein binding	9/4017	33/18639	0.272727272727273	1.26546269264716	0.269654997148294	0.726872441909816
GO:0005507	copper ion binding	16/4017	63/18639	0.253968253968254	1.1784202852164	0.271396323977603	0.730094336334116
GO:0042626	ATPase-coupled transmembrane transporter activity	24/4017	98/18639	0.244897959183673	1.13633384645867	0.273904179339436	0.735361220435393
GO:0003785	actin monomer binding	8/4017	29/18639	0.275862068965517	1.28000824083851	0.276418138325496	0.73815146111073
GO:0010484	histone H3 acetyltransferase activity	8/4017	29/18639	0.275862068965517	1.28000824083851	0.276418138325496	0.73815146111073
GO:0035591	signaling adaptor activity	31/4017	129/18639	0.24031007751938	1.11504593848238	0.276599762166399	0.73815146111073
GO:0004879	nuclear receptor activity	15/4017	59/18639	0.254237288135593	1.17966861178972	0.278975466080757	0.74300836284855
GO:0000030	mannosyltransferase activity	7/4017	25/18639	0.28	1.29920836445108	0.283252500917433	0.74843595598144
GO:0005537	D-mannose binding	7/4017	25/18639	0.28	1.29920836445108	0.283252500917433	0.74843595598144
GO:0019706	protein-cysteine S-palmitoyltransferase activity	7/4017	25/18639	0.28	1.29920836445108	0.283252500917433	0.74843595598144
GO:0019707	protein-cysteine S-acyltransferase activity	7/4017	25/18639	0.28	1.29920836445108	0.283252500917433	0.74843595598144
GO:0005548	phospholipid transporter activity	17/4017	68/18639	0.25	1.1600074682599	0.286266814897647	0.754908740666972
GO:0140313	molecular sequestering activity	14/4017	55/18639	0.254545454545455	1.18109851313735	0.286957251110247	0.75523985183937
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	6/4017	21/18639	0.285714285714286	1.32572282086845	0.290005315038007	0.755822819114649
GO:0010314	phosphatidylinositol-5-phosphate binding	6/4017	21/18639	0.285714285714286	1.32572282086845	0.290005315038007	0.755822819114649
GO:0051010	microtubule plus-end binding	6/4017	21/18639	0.285714285714286	1.32572282086845	0.290005315038007	0.755822819114649
GO:0070182	DNA polymerase binding	6/4017	21/18639	0.285714285714286	1.32572282086845	0.290005315038007	0.755822819114649
GO:0072542	protein phosphatase activator activity	6/4017	21/18639	0.285714285714286	1.32572282086845	0.290005315038007	0.755822819114649
GO:0042162	telomeric DNA binding	10/4017	38/18639	0.263157894736842	1.22106049290515	0.293116480714206	0.761961776026013
GO:0004536	DNA nuclease activity	16/4017	64/18639	0.25	1.1600074682599	0.294465559260729	0.761961776026013
GO:0070851	growth factor receptor binding	33/4017	139/18639	0.237410071942446	1.10158982597343	0.294467262513329	0.761961776026013
GO:0004843	cysteine-type deubiquitinase activity	26/4017	108/18639	0.240740740740741	1.11704422869471	0.295356508334139	0.761961776026013
GO:0005496	steroid binding	26/4017	108/18639	0.240740740740741	1.11704422869471	0.295356508334139	0.761961776026013
GO:0008484	sulfuric ester hydrolase activity	5/4017	17/18639	0.294117647058824	1.36471466854105	0.296350129793214	0.761961776026013
GO:1990226	histone methyltransferase binding	5/4017	17/18639	0.294117647058824	1.36471466854105	0.296350129793214	0.761961776026013
GO:0005338	nucleotide-sugar transmembrane transporter activity	4/4017	13/18639	0.307692307692308	1.42770149939679	0.301528976383958	0.768884701810926
GO:0015651	quaternary ammonium group transmembrane transporter activity	4/4017	13/18639	0.307692307692308	1.42770149939679	0.301528976383958	0.768884701810926
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	4/4017	13/18639	0.307692307692308	1.42770149939679	0.301528976383958	0.768884701810926
GO:0140852	histone ubiquitin ligase activity	4/4017	13/18639	0.307692307692308	1.42770149939679	0.301528976383958	0.768884701810926
GO:0090482	vitamin transmembrane transporter activity	9/4017	34/18639	0.264705882352941	1.22824320168695	0.301918076627327	0.768884701810926
GO:0098531	ligand-modulated transcription factor activity	15/4017	60/18639	0.25	1.1600074682599	0.303117006373306	0.770470413538231
GO:0008106	alcohol dehydrogenase (NADP+) activity	8/4017	30/18639	0.266666666666667	1.23734129947722	0.311273914028749	0.785028213738866
GO:0043995	histone H4K5 acetyltransferase activity	8/4017	30/18639	0.266666666666667	1.23734129947722	0.311273914028749	0.785028213738866
GO:0043996	histone H4K8 acetyltransferase activity	8/4017	30/18639	0.266666666666667	1.23734129947722	0.311273914028749	0.785028213738866
GO:0043997	histone H4K12 acetyltransferase activity	8/4017	30/18639	0.266666666666667	1.23734129947722	0.311273914028749	0.785028213738866
GO:0030170	pyridoxal phosphate binding	14/4017	56/18639	0.25	1.1600074682599	0.312275755589557	0.785028213738866
GO:0035091	phosphatidylinositol binding	65/4017	284/18639	0.22887323943662	1.06197866812526	0.312367247351591	0.785028213738866
GO:0008200	ion channel inhibitor activity	11/4017	43/18639	0.255813953488372	1.1869843861264	0.313849524691867	0.785799278114282
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	11/4017	43/18639	0.255813953488372	1.1869843861264	0.313849524691867	0.785799278114282
GO:0004519	endonuclease activity	30/4017	127/18639	0.236220472440945	1.09607004874951	0.316732251737491	0.791534617893505
GO:0044325	transmembrane transporter binding	32/4017	136/18639	0.235294117647059	1.09177173483284	0.317895156930623	0.792958628388512
GO:0004112	cyclic-nucleotide phosphodiesterase activity	7/4017	26/18639	0.269230769230769	1.2492388119722	0.32126231301651	0.796897425794201
GO:0008157	protein phosphatase 1 binding	7/4017	26/18639	0.269230769230769	1.2492388119722	0.32126231301651	0.796897425794201
GO:0050681	nuclear androgen receptor binding	7/4017	26/18639	0.269230769230769	1.2492388119722	0.32126231301651	0.796897425794201
GO:0030021	extracellular matrix structural constituent conferring compression resistance	6/4017	22/18639	0.272727272727273	1.26546269264716	0.33197751261475	0.81995160050824
GO:0140035	ubiquitin-like protein reader activity	6/4017	22/18639	0.272727272727273	1.26546269264716	0.33197751261475	0.81995160050824
GO:0043138	3'-5' DNA helicase activity	12/4017	48/18639	0.25	1.1600074682599	0.332396235957716	0.81995160050824
GO:0004386	helicase activity	36/4017	155/18639	0.232258064516129	1.07768435760919	0.335059078228877	0.824998135528561
GO:0016504	peptidase activator activity	14/4017	57/18639	0.245614035087719	1.13965646004481	0.338145927673904	0.829543312477082
GO:0070279	vitamin B6 binding	14/4017	57/18639	0.245614035087719	1.13965646004481	0.338145927673904	0.829543312477082
GO:0000900	mRNA regulatory element binding translation repressor activity	5/4017	18/18639	0.277777777777778	1.28889718695544	0.343527577900192	0.838132065059409
GO:0008308	voltage-gated monoatomic anion channel activity	5/4017	18/18639	0.277777777777778	1.28889718695544	0.343527577900192	0.838132065059409
GO:0098641	cadherin binding involved in cell-cell adhesion	5/4017	18/18639	0.277777777777778	1.28889718695544	0.343527577900192	0.838132065059409
GO:0016878	acid-thiol ligase activity	8/4017	31/18639	0.258064516129032	1.19742706401021	0.346943493633813	0.844167488285116
GO:0051213	dioxygenase activity	22/4017	93/18639	0.236559139784946	1.0976414753427	0.348777976845349	0.844167488285116
GO:0051219	phosphoprotein binding	22/4017	93/18639	0.236559139784946	1.0976414753427	0.348777976845349	0.844167488285116
GO:0008146	sulfotransferase activity	13/4017	53/18639	0.245283018867925	1.1381205348965	0.349158280494891	0.844167488285116
GO:0140296	general transcription initiation factor binding	13/4017	53/18639	0.245283018867925	1.1381205348965	0.349158280494891	0.844167488285116
GO:0030331	nuclear estrogen receptor binding	10/4017	40/18639	0.25	1.1600074682599	0.355580841080576	0.845449024586162
GO:0032451	demethylase activity	10/4017	40/18639	0.25	1.1600074682599	0.355580841080576	0.845449024586162
GO:0005545	1-phosphatidylinositol binding	4/4017	14/18639	0.285714285714286	1.32572282086845	0.356011818131645	0.845449024586162
GO:0008191	metalloendopeptidase inhibitor activity	4/4017	14/18639	0.285714285714286	1.32572282086845	0.356011818131645	0.845449024586162
GO:0008195	phosphatidate phosphatase activity	4/4017	14/18639	0.285714285714286	1.32572282086845	0.356011818131645	0.845449024586162
GO:0008559	ABC-type xenobiotic transporter activity	4/4017	14/18639	0.285714285714286	1.32572282086845	0.356011818131645	0.845449024586162
GO:0016530	metallochaperone activity	4/4017	14/18639	0.285714285714286	1.32572282086845	0.356011818131645	0.845449024586162
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	4/4017	14/18639	0.285714285714286	1.32572282086845	0.356011818131645	0.845449024586162
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	4/4017	14/18639	0.285714285714286	1.32572282086845	0.356011818131645	0.845449024586162
GO:0071933	Arp2/3 complex binding	4/4017	14/18639	0.285714285714286	1.32572282086845	0.356011818131645	0.845449024586162
GO:0004683	calcium/calmodulin-dependent protein kinase activity	7/4017	27/18639	0.259259259259259	1.20297070782508	0.360029544086605	0.845690259724874
GO:0016409	palmitoyltransferase activity	9/4017	36/18639	0.25	1.1600074682599	0.368684281428106	0.845690259724874
GO:0016798	hydrolase activity, acting on glycosyl bonds	30/4017	130/18639	0.230769230769231	1.0707761245476	0.368720210802325	0.845690259724874
GO:0004090	carbonyl reductase (NADPH) activity	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0004382	GDP phosphatase activity	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0008140	cAMP response element binding protein binding	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0032052	bile acid binding	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0035256	G protein-coupled glutamate receptor binding	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0050815	phosphoserine residue binding	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0051864	histone H3K36 demethylase activity	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0051880	G-quadruplex DNA binding	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0099122	RNA polymerase II C-terminal domain binding	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0140940	histone H2A methyltransferase activity	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:1990259	histone H2AQ104 methyltransferase activity	3/4017	10/18639	0.3	1.39200896191187	0.369396493402637	0.845690259724874
GO:0004715	non-membrane spanning protein tyrosine kinase activity	11/4017	45/18639	0.244444444444444	1.13422952452079	0.37369136724586	0.847427203653166
GO:0140303	intramembrane lipid transporter activity	11/4017	45/18639	0.244444444444444	1.13422952452079	0.37369136724586	0.847427203653166
GO:0003887	DNA-directed DNA polymerase activity	6/4017	23/18639	0.260869565217391	1.21044257557554	0.374591980074062	0.847427203653166
GO:0005158	insulin receptor binding	6/4017	23/18639	0.260869565217391	1.21044257557554	0.374591980074062	0.847427203653166
GO:0005212	structural constituent of eye lens	6/4017	23/18639	0.260869565217391	1.21044257557554	0.374591980074062	0.847427203653166
GO:0031681	G-protein beta-subunit binding	6/4017	23/18639	0.260869565217391	1.21044257557554	0.374591980074062	0.847427203653166
GO:0044013	histone H2B acetyltransferase activity	6/4017	23/18639	0.260869565217391	1.21044257557554	0.374591980074062	0.847427203653166
GO:0015485	cholesterol binding	13/4017	54/18639	0.240740740740741	1.11704422869471	0.376693885676712	0.850742778969196
GO:0042277	peptide binding	56/4017	249/18639	0.224899598393574	1.04354085498079	0.382840928781827	0.863167490356328
GO:0046624	sphingolipid transporter activity	5/4017	19/18639	0.263157894736842	1.22106049290515	0.391115462965084	0.880339013441613
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	7/4017	28/18639	0.25	1.1600074682599	0.399134207535452	0.896878042814957
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	21/4017	91/18639	0.230769230769231	1.0707761245476	0.401455032624691	0.900579494327537
GO:0004129	cytochrome-c oxidase activity	4/4017	15/18639	0.266666666666667	1.23734129947722	0.410413018720496	0.914537010048838
GO:0008252	nucleotidase activity	4/4017	15/18639	0.266666666666667	1.23734129947722	0.410413018720496	0.914537010048838
GO:0010181	FMN binding	4/4017	15/18639	0.266666666666667	1.23734129947722	0.410413018720496	0.914537010048838
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	4/4017	15/18639	0.266666666666667	1.23734129947722	0.410413018720496	0.914537010048838
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	6/4017	24/18639	0.25	1.1600074682599	0.417311620397186	0.922718886512307
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	6/4017	24/18639	0.25	1.1600074682599	0.417311620397186	0.922718886512307
GO:0005315	phosphate transmembrane transporter activity	6/4017	24/18639	0.25	1.1600074682599	0.417311620397186	0.922718886512307
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	6/4017	24/18639	0.25	1.1600074682599	0.417311620397186	0.922718886512307
GO:0004222	metalloendopeptidase activity	25/4017	110/18639	0.227272727272727	1.05455224387263	0.418608106934305	0.922718886512307
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	8/4017	33/18639	0.242424242424242	1.12485572679747	0.419389808020553	0.922718886512307
GO:0019239	deaminase activity	8/4017	33/18639	0.242424242424242	1.12485572679747	0.419389808020553	0.922718886512307
GO:0035198	miRNA binding	10/4017	42/18639	0.238095238095238	1.10476901739038	0.419605896035514	0.922718886512307
GO:0035401	histone H3Y41 kinase activity	26/4017	115/18639	0.226086956521739	1.04905023216547	0.427207261461454	0.928919459623732
GO:0140801	histone H2AXY142 kinase activity	26/4017	115/18639	0.226086956521739	1.04905023216547	0.427207261461454	0.928919459623732
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/4017	11/18639	0.272727272727273	1.26546269264716	0.43402872023485	0.928919459623732
GO:0005536	D-glucose binding	3/4017	11/18639	0.272727272727273	1.26546269264716	0.43402872023485	0.928919459623732
GO:0008526	phosphatidylinositol transfer activity	3/4017	11/18639	0.272727272727273	1.26546269264716	0.43402872023485	0.928919459623732
GO:0015173	aromatic amino acid transmembrane transporter activity	3/4017	11/18639	0.272727272727273	1.26546269264716	0.43402872023485	0.928919459623732
GO:0019203	carbohydrate phosphatase activity	3/4017	11/18639	0.272727272727273	1.26546269264716	0.43402872023485	0.928919459623732
GO:0034056	estrogen response element binding	3/4017	11/18639	0.272727272727273	1.26546269264716	0.43402872023485	0.928919459623732
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	3/4017	11/18639	0.272727272727273	1.26546269264716	0.43402872023485	0.928919459623732
GO:0035252	UDP-xylosyltransferase activity	3/4017	11/18639	0.272727272727273	1.26546269264716	0.43402872023485	0.928919459623732
GO:0042285	xylosyltransferase activity	3/4017	11/18639	0.272727272727273	1.26546269264716	0.43402872023485	0.928919459623732
GO:0045294	alpha-catenin binding	3/4017	11/18639	0.272727272727273	1.26546269264716	0.43402872023485	0.928919459623732
GO:0047676	arachidonate-CoA ligase activity	3/4017	11/18639	0.272727272727273	1.26546269264716	0.43402872023485	0.928919459623732
GO:0140031	phosphorylation-dependent protein binding	3/4017	11/18639	0.272727272727273	1.26546269264716	0.43402872023485	0.928919459623732
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/4017	11/18639	0.272727272727273	1.26546269264716	0.43402872023485	0.928919459623732
GO:0140359	ABC-type transporter activity	11/4017	47/18639	0.234042553191489	1.08596443837097	0.434588607100253	0.928919459623732
GO:1990518	single-stranded 3'-5' DNA helicase activity	11/4017	47/18639	0.234042553191489	1.08596443837097	0.434588607100253	0.928919459623732
GO:0005109	frizzled binding	9/4017	38/18639	0.236842105263158	1.09895444361464	0.436633108997901	0.928919459623732
GO:0042887	amide transmembrane transporter activity	9/4017	38/18639	0.236842105263158	1.09895444361464	0.436633108997901	0.928919459623732
GO:0043531	ADP binding	9/4017	38/18639	0.236842105263158	1.09895444361464	0.436633108997901	0.928919459623732
GO:0106222	lncRNA binding	7/4017	29/18639	0.241379310344828	1.12000721073369	0.438180229556802	0.928919459623732
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	5/4017	20/18639	0.25	1.1600074682599	0.438405519089435	0.928919459623732
GO:0010851	cyclase regulator activity	5/4017	20/18639	0.25	1.1600074682599	0.438405519089435	0.928919459623732
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	12/4017	52/18639	0.230769230769231	1.0707761245476	0.448010409080773	0.947768855919293
GO:0008375	acetylglucosaminyltransferase activity	10/4017	43/18639	0.232558139534884	1.07907671466037	0.451653281291165	0.953965935365383
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	6/4017	25/18639	0.24	1.1136071695295	0.459646079180265	0.965809480232952
GO:0003688	DNA replication origin binding	4/4017	16/18639	0.25	1.1600074682599	0.463761919453669	0.965809480232952
GO:0005159	insulin-like growth factor receptor binding	4/4017	16/18639	0.25	1.1600074682599	0.463761919453669	0.965809480232952
GO:0005521	lamin binding	4/4017	16/18639	0.25	1.1600074682599	0.463761919453669	0.965809480232952
GO:0015562	efflux transmembrane transporter activity	4/4017	16/18639	0.25	1.1600074682599	0.463761919453669	0.965809480232952
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/4017	16/18639	0.25	1.1600074682599	0.463761919453669	0.965809480232952
GO:0022858	alanine transmembrane transporter activity	4/4017	16/18639	0.25	1.1600074682599	0.463761919453669	0.965809480232952
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/4017	16/18639	0.25	1.1600074682599	0.463761919453669	0.965809480232952
GO:0034450	ubiquitin-ubiquitin ligase activity	4/4017	16/18639	0.25	1.1600074682599	0.463761919453669	0.965809480232952
GO:0009378	four-way junction helicase activity	11/4017	48/18639	0.229166666666667	1.06334017923824	0.464970122845332	0.96621161465062
GO:0004713	protein tyrosine kinase activity	31/4017	140/18639	0.221428571428571	1.02743518617305	0.465400358889304	0.96621161465062
GO:0140299	molecular sensor activity	16/4017	71/18639	0.225352112676056	1.04564053476948	0.466276735520708	0.966530225412692
GO:0001968	fibronectin binding	7/4017	30/18639	0.233333333333333	1.08267363704257	0.47680389080447	0.984062411382588
GO:0005246	calcium channel regulator activity	12/4017	53/18639	0.226415094339623	1.05057280144292	0.476942739398591	0.984062411382588
GO:0005544	calcium-dependent phospholipid binding	12/4017	53/18639	0.226415094339623	1.05057280144292	0.476942739398591	0.984062411382588
GO:0001846	opsonin binding	5/4017	21/18639	0.238095238095238	1.10476901739038	0.484780582855507	0.997156368119713
GO:0140312	cargo adaptor activity	5/4017	21/18639	0.238095238095238	1.10476901739038	0.484780582855507	0.997156368119713
GO:0061980	regulatory RNA binding	13/4017	58/18639	0.224137931034483	1.04000669568129	0.487828846578552	0.997224410428286
GO:0005154	epidermal growth factor receptor binding	8/4017	35/18639	0.228571428571429	1.06057825669476	0.49124326989057	0.997224410428286
GO:0034061	DNA polymerase activity	8/4017	35/18639	0.228571428571429	1.06057825669476	0.49124326989057	0.997224410428286
GO:0043015	gamma-tubulin binding	8/4017	35/18639	0.228571428571429	1.06057825669476	0.49124326989057	0.997224410428286
GO:0004126	cytidine deaminase activity	3/4017	12/18639	0.25	1.1600074682599	0.49600167010831	0.997224410428286
GO:0010853	cyclase activator activity	3/4017	12/18639	0.25	1.1600074682599	0.49600167010831	0.997224410428286
GO:0015368	calcium:monoatomic cation antiporter activity	3/4017	12/18639	0.25	1.1600074682599	0.49600167010831	0.997224410428286
GO:0016208	AMP binding	3/4017	12/18639	0.25	1.1600074682599	0.49600167010831	0.997224410428286
GO:0016801	hydrolase activity, acting on ether bonds	3/4017	12/18639	0.25	1.1600074682599	0.49600167010831	0.997224410428286
GO:0016803	ether hydrolase activity	3/4017	12/18639	0.25	1.1600074682599	0.49600167010831	0.997224410428286
GO:0034452	dynactin binding	3/4017	12/18639	0.25	1.1600074682599	0.49600167010831	0.997224410428286
GO:0035497	cAMP response element binding	3/4017	12/18639	0.25	1.1600074682599	0.49600167010831	0.997224410428286
GO:0036009	protein-glutamine N-methyltransferase activity	3/4017	12/18639	0.25	1.1600074682599	0.49600167010831	0.997224410428286
GO:0097677	STAT family protein binding	3/4017	12/18639	0.25	1.1600074682599	0.49600167010831	0.997224410428286
GO:0141221	histone deacetylase activity, hydrolytic mechanism	3/4017	12/18639	0.25	1.1600074682599	0.49600167010831	0.997224410428286
GO:0051139	metal cation:proton antiporter activity	6/4017	26/18639	0.230769230769231	1.0707761245476	0.501161209029391	1
GO:0120014	phospholipid transfer activity	6/4017	26/18639	0.230769230769231	1.0707761245476	0.501161209029391	1
GO:0050997	quaternary ammonium group binding	9/4017	40/18639	0.225	1.04400672143391	0.503748711520656	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	12/4017	54/18639	0.222222222222222	1.03111774956435	0.505585269033414	1
GO:0008327	methyl-CpG binding	7/4017	31/18639	0.225806451612903	1.04774868100894	0.514679839979245	1
GO:0016411	acylglycerol O-acyltransferase activity	7/4017	31/18639	0.225806451612903	1.04774868100894	0.514679839979245	1
GO:0045309	protein phosphorylated amino acid binding	13/4017	59/18639	0.220338983050847	1.02237946355109	0.515185358680685	1
GO:0038191	neuropilin binding	4/4017	17/18639	0.235294117647059	1.09177173483284	0.515273239349194	1
GO:0017124	SH3 domain binding	25/4017	115/18639	0.217391304347826	1.00870214631295	0.517253059330943	1
GO:0004033	aldo-keto reductase (NADPH) activity	8/4017	36/18639	0.222222222222222	1.03111774956435	0.526260123736988	1
GO:0004407	histone deacetylase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0008093	cytoskeletal anchor activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0008970	phospholipase A1 activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0031683	G-protein beta/gamma-subunit complex binding	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0032931	histone H3K56 acetyltransferase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0033558	protein lysine deacetylase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0043992	histone H3K9 acetyltransferase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0043993	histone H3K18 acetyltransferase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0043994	histone H3K23 acetyltransferase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0043999	histone H2AK5 acetyltransferase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0044012	histone H2AK9 acetyltransferase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0044014	histone H2BK5 acetyltransferase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0044015	histone H2BK12 acetyltransferase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0044016	histone H3K4 acetyltransferase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0044017	histone H3K27 acetyltransferase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0044018	histone H3K36 acetyltransferase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0046972	histone H4K16 acetyltransferase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0050321	tau-protein kinase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0140908	histone H3K122 acetyltransferase activity	5/4017	22/18639	0.227272727272727	1.05455224387263	0.529722662338083	1
GO:0008374	O-acyltransferase activity	12/4017	55/18639	0.218181818181818	1.01237015411773	0.533803620206952	1
GO:0140828	metal cation:monoatomic cation antiporter activity	9/4017	41/18639	0.219512195121951	1.01854314286235	0.536440752386967	1
GO:0003678	DNA helicase activity	16/4017	74/18639	0.216216216216216	1.00324970227883	0.539929860498533	1
GO:0015252	proton channel activity	6/4017	27/18639	0.222222222222222	1.03111774956435	0.541484541870187	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	10/4017	46/18639	0.217391304347826	1.00870214631295	0.545562308479767	1
GO:0008378	galactosyltransferase activity	7/4017	32/18639	0.21875	1.01500653472741	0.551524866392947	1
GO:0043425	bHLH transcription factor binding	7/4017	32/18639	0.21875	1.01500653472741	0.551524866392947	1
GO:0004725	protein tyrosine phosphatase activity	21/4017	98/18639	0.214285714285714	0.994292115651339	0.551681355439513	1
GO:0002161	aminoacyl-tRNA editing activity	3/4017	13/18639	0.230769230769231	1.0707761245476	0.554343478225616	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	3/4017	13/18639	0.230769230769231	1.0707761245476	0.554343478225616	1
GO:0005172	vascular endothelial growth factor receptor binding	3/4017	13/18639	0.230769230769231	1.0707761245476	0.554343478225616	1
GO:0008035	high-density lipoprotein particle binding	3/4017	13/18639	0.230769230769231	1.0707761245476	0.554343478225616	1
GO:0008253	5'-nucleotidase activity	3/4017	13/18639	0.230769230769231	1.0707761245476	0.554343478225616	1
GO:0019104	DNA N-glycosylase activity	3/4017	13/18639	0.230769230769231	1.0707761245476	0.554343478225616	1
GO:0039706	co-receptor binding	3/4017	13/18639	0.230769230769231	1.0707761245476	0.554343478225616	1
GO:0046974	histone H3K9 methyltransferase activity	3/4017	13/18639	0.230769230769231	1.0707761245476	0.554343478225616	1
GO:0070700	BMP receptor binding	3/4017	13/18639	0.230769230769231	1.0707761245476	0.554343478225616	1
GO:0019208	phosphatase regulator activity	25/4017	117/18639	0.213675213675214	0.991459374581107	0.555855639231308	1
GO:0019842	vitamin binding	32/4017	150/18639	0.213333333333333	0.989873039581778	0.558289531242378	1
GO:0019838	growth factor binding	29/4017	136/18639	0.213235294117647	0.989418134692264	0.559741145581123	1
GO:0106310	protein serine kinase activity	77/4017	361/18639	0.213296398891967	0.989701662670493	0.562244855837999	1
GO:0008525	phosphatidylcholine transporter activity	4/4017	18/18639	0.222222222222222	1.03111774956435	0.564343428334623	1
GO:0015172	acidic amino acid transmembrane transporter activity	4/4017	18/18639	0.222222222222222	1.03111774956435	0.564343428334623	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	4/4017	18/18639	0.222222222222222	1.03111774956435	0.564343428334623	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	4/4017	18/18639	0.222222222222222	1.03111774956435	0.564343428334623	1
GO:1901611	phosphatidylglycerol binding	4/4017	18/18639	0.222222222222222	1.03111774956435	0.564343428334623	1
GO:0042826	histone deacetylase binding	27/4017	127/18639	0.21259842519685	0.986463043874557	0.56697051569595	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	5/4017	23/18639	0.217391304347826	1.00870214631295	0.572814518522533	1
GO:0061749	forked DNA-dependent helicase activity	10/4017	47/18639	0.212765957446809	0.98724039851906	0.5755552007445	1
GO:0140938	histone H3 methyltransferase activity	10/4017	47/18639	0.212765957446809	0.98724039851906	0.5755552007445	1
GO:0045499	chemorepellent activity	6/4017	28/18639	0.214285714285714	0.994292115651339	0.580307360325115	1
GO:0046875	ephrin receptor binding	6/4017	28/18639	0.214285714285714	0.994292115651339	0.580307360325115	1
GO:0001618	virus receptor activity	17/4017	81/18639	0.209876543209877	0.97383343014411	0.592793487775308	1
GO:0030971	receptor tyrosine kinase binding	17/4017	81/18639	0.209876543209877	0.97383343014411	0.592793487775308	1
GO:1901681	sulfur compound binding	58/4017	275/18639	0.210909090909091	0.978624482313803	0.598023247480024	1
GO:0048156	tau protein binding	9/4017	43/18639	0.209302325581395	0.971169043194331	0.599183148397186	1
GO:0033218	amide binding	52/4017	247/18639	0.210526315789474	0.976848394324123	0.601168247658562	1
GO:0042393	histone binding	52/4017	247/18639	0.210526315789474	0.976848394324123	0.601168247658562	1
GO:0036121	double-stranded DNA helicase activity	10/4017	48/18639	0.208333333333333	0.96667289021658	0.604656537033756	1
GO:0004065	arylsulfatase activity	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0005313	L-glutamate transmembrane transporter activity	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0008331	high voltage-gated calcium channel activity	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0008392	arachidonate epoxygenase activity	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0015386	potassium:proton antiporter activity	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0019992	diacylglycerol binding	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0034236	protein kinase A catalytic subunit binding	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0042043	neurexin family protein binding	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0043176	amine binding	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0044548	S100 protein binding	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0046030	inositol trisphosphate phosphatase activity	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0061665	SUMO ligase activity	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0070742	C2H2 zinc finger domain binding	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:1901612	cardiolipin binding	3/4017	14/18639	0.214285714285714	0.994292115651339	0.608433930978517	1
GO:0022821	solute:potassium antiporter activity	4/4017	19/18639	0.210526315789474	0.976848394324123	0.610537552433166	1
GO:0050145	nucleoside monophosphate kinase activity	4/4017	19/18639	0.210526315789474	0.976848394324123	0.610537552433166	1
GO:0140036	ubiquitin-modified protein reader activity	4/4017	19/18639	0.210526315789474	0.976848394324123	0.610537552433166	1
GO:1990380	K48-linked deubiquitinase activity	4/4017	19/18639	0.210526315789474	0.976848394324123	0.610537552433166	1
GO:0001091	RNA polymerase II general transcription initiation factor binding	5/4017	24/18639	0.208333333333333	0.96667289021658	0.613736333818677	1
GO:0043998	histone H2A acetyltransferase activity	5/4017	24/18639	0.208333333333333	0.96667289021658	0.613736333818677	1
GO:0050431	transforming growth factor beta binding	5/4017	24/18639	0.208333333333333	0.96667289021658	0.613736333818677	1
GO:0140272	exogenous protein binding	17/4017	82/18639	0.207317073170732	0.961957412703328	0.61488779801159	1
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	6/4017	29/18639	0.206896551724138	0.960006180628879	0.61738400313424	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/4017	29/18639	0.206896551724138	0.960006180628879	0.61738400313424	1
GO:0097472	cyclin-dependent protein kinase activity	6/4017	29/18639	0.206896551724138	0.960006180628879	0.61738400313424	1
GO:0008081	phosphoric diester hydrolase activity	18/4017	87/18639	0.206896551724138	0.960006180628879	0.619467084322911	1
GO:0008376	acetylgalactosaminyltransferase activity	7/4017	34/18639	0.205882352941176	0.955300267978737	0.621209065194065	1
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	7/4017	34/18639	0.205882352941176	0.955300267978737	0.621209065194065	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	8/4017	39/18639	0.205128205128205	0.951800999597863	0.625083561722208	1
GO:0008194	UDP-glycosyltransferase activity	30/4017	145/18639	0.206896551724138	0.960006180628879	0.632271472699633	1
GO:0019888	protein phosphatase regulator activity	22/4017	107/18639	0.205607476635514	0.954024833709073	0.636169552826724	1
GO:0030165	PDZ domain binding	17/4017	83/18639	0.204819277108434	0.950367564357505	0.636421290785684	1
GO:0001786	phosphatidylserine binding	12/4017	59/18639	0.203389830508475	0.943734889431779	0.640168293329612	1
GO:0070888	E-box binding	12/4017	59/18639	0.203389830508475	0.943734889431779	0.640168293329612	1
GO:0003707	nuclear steroid receptor activity	5/4017	25/18639	0.2	0.928005974607916	0.65225889747828	1
GO:0031210	phosphatidylcholine binding	6/4017	30/18639	0.2	0.928005974607916	0.652529031216683	1
GO:0033612	receptor serine/threonine kinase binding	6/4017	30/18639	0.2	0.928005974607916	0.652529031216683	1
GO:0046332	SMAD binding	16/4017	79/18639	0.20253164556962	0.939752885678903	0.654063405616994	1
GO:0004467	long-chain fatty acid-CoA ligase activity	3/4017	15/18639	0.2	0.928005974607916	0.657939159043022	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	3/4017	15/18639	0.2	0.928005974607916	0.657939159043022	1
GO:0008242	omega peptidase activity	3/4017	15/18639	0.2	0.928005974607916	0.657939159043022	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/4017	15/18639	0.2	0.928005974607916	0.657939159043022	1
GO:0034483	heparan sulfate sulfotransferase activity	3/4017	15/18639	0.2	0.928005974607916	0.657939159043022	1
GO:0048531	beta-1,3-galactosyltransferase activity	3/4017	15/18639	0.2	0.928005974607916	0.657939159043022	1
GO:0050700	CARD domain binding	3/4017	15/18639	0.2	0.928005974607916	0.657939159043022	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	3/4017	15/18639	0.2	0.928005974607916	0.657939159043022	1
GO:0141050	histone H3K deacetylase activity	3/4017	15/18639	0.2	0.928005974607916	0.657939159043022	1
GO:0141051	histone H4K deacetylase activity	3/4017	15/18639	0.2	0.928005974607916	0.657939159043022	1
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	18/4017	89/18639	0.202247191011236	0.938433008030477	0.660558672888253	1
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	18/4017	89/18639	0.202247191011236	0.938433008030477	0.660558672888253	1
GO:0120013	lipid transfer activity	13/4017	65/18639	0.2	0.928005974607916	0.667239143685689	1
GO:0000182	rDNA binding	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0005031	tumor necrosis factor receptor activity	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0005345	purine nucleobase transmembrane transporter activity	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0015203	polyamine transmembrane transporter activity	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0032356	oxidized DNA binding	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0042975	peroxisome proliferator activated receptor binding	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0043208	glycosphingolipid binding	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0050308	sugar-phosphatase activity	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0140135	mechanosensitive monoatomic cation channel activity	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0140999	histone H3K4 trimethyltransferase activity	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0141109	transporter activator activity	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/4017	10/18639	0.2	0.928005974607916	0.669280367289879	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	37/4017	181/18639	0.204419889502762	0.948514393936268	0.670745003595496	1
GO:0140793	histone H2AXY142 phosphatase activity	18/4017	90/18639	0.2	0.928005974607916	0.68020024444051	1
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	8/4017	41/18639	0.195121951219512	0.905371682544309	0.68426006745699	1
GO:0045505	dynein intermediate chain binding	7/4017	36/18639	0.194444444444444	0.902228030868808	0.684461987536513	1
GO:0030276	clathrin binding	9/4017	46/18639	0.195652173913043	0.907831931681657	0.684698497571133	1
GO:0047499	calcium-independent phospholipase A2 activity	6/4017	31/18639	0.193548387096774	0.898070298007661	0.685612837113668	1
GO:0140457	protein demethylase activity	6/4017	31/18639	0.193548387096774	0.898070298007661	0.685612837113668	1
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/4017	26/18639	0.192307692307692	0.892313437122997	0.688234537585159	1
GO:0030247	polysaccharide binding	5/4017	26/18639	0.192307692307692	0.892313437122997	0.688234537585159	1
GO:0050750	low-density lipoprotein particle receptor binding	5/4017	26/18639	0.192307692307692	0.892313437122997	0.688234537585159	1
GO:0052742	phosphatidylinositol kinase activity	5/4017	26/18639	0.192307692307692	0.892313437122997	0.688234537585159	1
GO:0005201	extracellular matrix structural constituent	34/4017	168/18639	0.202380952380952	0.93905366478182	0.690355898241513	1
GO:0019955	cytokine binding	29/4017	144/18639	0.201388888888889	0.934450460542694	0.691913746511728	1
GO:0009975	cyclase activity	4/4017	21/18639	0.19047619047619	0.883815213912301	0.693285849689944	1
GO:0036122	BMP binding	4/4017	21/18639	0.19047619047619	0.883815213912301	0.693285849689944	1
GO:0061891	calcium ion sensor activity	4/4017	21/18639	0.19047619047619	0.883815213912301	0.693285849689944	1
GO:0017022	myosin binding	15/4017	76/18639	0.197368421052632	0.915795369678865	0.693381913405887	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	17/4017	86/18639	0.197674418604651	0.917215207461313	0.697216949402851	1
GO:0008391	arachidonate monooxygenase activity	3/4017	16/18639	0.1875	0.870005601194922	0.702749291255949	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/4017	16/18639	0.1875	0.870005601194922	0.702749291255949	1
GO:0070411	I-SMAD binding	3/4017	16/18639	0.1875	0.870005601194922	0.702749291255949	1
GO:0140327	flippase activity	3/4017	16/18639	0.1875	0.870005601194922	0.702749291255949	1
GO:0140328	floppase activity	3/4017	16/18639	0.1875	0.870005601194922	0.702749291255949	1
GO:1902936	phosphatidylinositol bisphosphate binding	22/4017	111/18639	0.198198198198198	0.919645560422259	0.707275955566724	1
GO:0001784	phosphotyrosine residue binding	9/4017	47/18639	0.191489361702128	0.888516358667154	0.710548225766914	1
GO:0004520	DNA endonuclease activity	8/4017	42/18639	0.19047619047619	0.883815213912301	0.711543658830592	1
GO:0031492	nucleosomal DNA binding	8/4017	42/18639	0.19047619047619	0.883815213912301	0.711543658830592	1
GO:0022804	active transmembrane transporter activity	94/4017	457/18639	0.205689277899344	0.954404394016894	0.714918728122799	1
GO:0042910	xenobiotic transmembrane transporter activity	6/4017	32/18639	0.1875	0.870005601194922	0.716556214972296	1
GO:0120015	sterol transfer activity	6/4017	32/18639	0.1875	0.870005601194922	0.716556214972296	1
GO:0043178	alcohol binding	18/4017	92/18639	0.195652173913043	0.907831931681657	0.71751767764553	1
GO:0000099	sulfur amino acid transmembrane transporter activity	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:0003953	NAD+ nucleosidase activity	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:0008503	benzodiazepine receptor activity	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:0015205	nucleobase transmembrane transporter activity	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:0034713	type I transforming growth factor beta receptor binding	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:0042608	T cell receptor binding	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:0048185	activin binding	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:0097493	structural molecule activity conferring elasticity	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:1990948	ubiquitin ligase inhibitor activity	2/4017	11/18639	0.181818181818182	0.843641795098106	0.721558511079886	1
GO:0005044	scavenger receptor activity	5/4017	27/18639	0.185185185185185	0.859264791303626	0.721586809338561	1
GO:0005104	fibroblast growth factor receptor binding	5/4017	27/18639	0.185185185185185	0.859264791303626	0.721586809338561	1
GO:0035255	ionotropic glutamate receptor binding	5/4017	27/18639	0.185185185185185	0.859264791303626	0.721586809338561	1
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	5/4017	27/18639	0.185185185185185	0.859264791303626	0.721586809338561	1
GO:0070034	telomerase RNA binding	4/4017	22/18639	0.181818181818182	0.843641795098106	0.729633224657024	1
GO:0140784	metal ion sensor activity	4/4017	22/18639	0.181818181818182	0.843641795098106	0.729633224657024	1
GO:0004857	enzyme inhibitor activity	85/4017	416/18639	0.204326923076923	0.948083026943184	0.73065879053101	1
GO:0017116	single-stranded DNA helicase activity	11/4017	58/18639	0.189655172413793	0.880005665576472	0.732654628530613	1
GO:0005245	voltage-gated calcium channel activity	8/4017	43/18639	0.186046511627907	0.863261371728294	0.737226061215371	1
GO:0046982	protein heterodimerization activity	75/4017	369/18639	0.203252032520325	0.943095502650321	0.737510950392655	1
GO:0005085	guanyl-nucleotide exchange factor activity	46/4017	230/18639	0.2	0.928005974607916	0.741461733295561	1
GO:0005092	GDP-dissociation inhibitor activity	3/4017	17/18639	0.176470588235294	0.818828801124632	0.742922730950255	1
GO:0008429	phosphatidylethanolamine binding	3/4017	17/18639	0.176470588235294	0.818828801124632	0.742922730950255	1
GO:0032183	SUMO binding	3/4017	17/18639	0.176470588235294	0.818828801124632	0.742922730950255	1
GO:0046965	nuclear retinoid X receptor binding	3/4017	17/18639	0.176470588235294	0.818828801124632	0.742922730950255	1
GO:0070492	oligosaccharide binding	3/4017	17/18639	0.176470588235294	0.818828801124632	0.742922730950255	1
GO:0031491	nucleosome binding	14/4017	74/18639	0.189189189189189	0.877843489493975	0.751457376920884	1
GO:0141052	histone H3 demethylase activity	5/4017	28/18639	0.178571428571429	0.828576763042782	0.752299733037136	1
GO:0004674	protein serine/threonine kinase activity	88/4017	433/18639	0.203233256351039	0.943008380663933	0.752494544308497	1
GO:0004620	phospholipase activity	21/4017	109/18639	0.192660550458716	0.89395070948469	0.754046769841382	1
GO:0140857	histone H3T45 kinase activity	49/4017	246/18639	0.199186991869919	0.924233592597315	0.757312840917074	1
GO:0005319	lipid transporter activity	35/4017	178/18639	0.196629213483146	0.912365424474075	0.75761477026591	1
GO:0035254	glutamate receptor binding	9/4017	49/18639	0.183673469387755	0.852250384844005	0.75798674541529	1
GO:0140996	histone H3 kinase activity	72/4017	357/18639	0.201680672268908	0.935804344142437	0.758317505701524	1
GO:0004175	endopeptidase activity	82/4017	405/18639	0.202469135802469	0.939462838491965	0.758372954711433	1
GO:0017134	fibroblast growth factor binding	4/4017	23/18639	0.173913043478261	0.806961717050362	0.76264768910639	1
GO:0000217	DNA secondary structure binding	7/4017	39/18639	0.179487179487179	0.83282587464813	0.765783575048196	1
GO:0005543	phospholipid binding	101/4017	497/18639	0.203219315895372	0.942943696533195	0.766199584042517	1
GO:0003720	telomerase activity	2/4017	12/18639	0.166666666666667	0.773338312173264	0.766669879274201	1
GO:0005078	MAP-kinase scaffold activity	2/4017	12/18639	0.166666666666667	0.773338312173264	0.766669879274201	1
GO:0005095	GTPase inhibitor activity	2/4017	12/18639	0.166666666666667	0.773338312173264	0.766669879274201	1
GO:0005436	sodium:phosphate symporter activity	2/4017	12/18639	0.166666666666667	0.773338312173264	0.766669879274201	1
GO:0008179	adenylate cyclase binding	2/4017	12/18639	0.166666666666667	0.773338312173264	0.766669879274201	1
GO:0008603	cAMP-dependent protein kinase regulator activity	2/4017	12/18639	0.166666666666667	0.773338312173264	0.766669879274201	1
GO:0015166	polyol transmembrane transporter activity	2/4017	12/18639	0.166666666666667	0.773338312173264	0.766669879274201	1
GO:0017166	vinculin binding	2/4017	12/18639	0.166666666666667	0.773338312173264	0.766669879274201	1
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/4017	12/18639	0.166666666666667	0.773338312173264	0.766669879274201	1
GO:0042301	phosphate ion binding	2/4017	12/18639	0.166666666666667	0.773338312173264	0.766669879274201	1
GO:0070008	serine-type exopeptidase activity	2/4017	12/18639	0.166666666666667	0.773338312173264	0.766669879274201	1
GO:0070679	inositol 1,4,5 trisphosphate binding	2/4017	12/18639	0.166666666666667	0.773338312173264	0.766669879274201	1
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/4017	12/18639	0.166666666666667	0.773338312173264	0.766669879274201	1
GO:0035403	histone H3T6 kinase activity	49/4017	247/18639	0.198380566801619	0.920491756190039	0.767475560680816	1
GO:0048306	calcium-dependent protein binding	15/4017	80/18639	0.1875	0.870005601194922	0.768907476377448	1
GO:0016298	lipase activity	25/4017	130/18639	0.192307692307692	0.892313437122997	0.771549674743852	1
GO:0030332	cyclin binding	6/4017	34/18639	0.176470588235294	0.818828801124632	0.771920460209119	1
GO:0141003	histone H2AX kinase activity	71/4017	354/18639	0.200564971751412	0.930627460411894	0.773618155092457	1
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	48/4017	243/18639	0.197530864197531	0.916549110723868	0.775999828667941	1
GO:0017075	syntaxin-1 binding	3/4017	18/18639	0.166666666666667	0.773338312173264	0.778638591473381	1
GO:0034185	apolipoprotein binding	3/4017	18/18639	0.166666666666667	0.773338312173264	0.778638591473381	1
GO:0035615	clathrin adaptor activity	3/4017	18/18639	0.166666666666667	0.773338312173264	0.778638591473381	1
GO:0051861	glycolipid binding	5/4017	29/18639	0.172413793103448	0.800005150524066	0.780407176766906	1
GO:0035173	histone kinase activity	72/4017	360/18639	0.2	0.928005974607916	0.78324388840261	1
GO:0072341	modified amino acid binding	17/4017	91/18639	0.186813186813187	0.866818767490911	0.784156514046557	1
GO:0005178	integrin binding	31/4017	161/18639	0.192546583850932	0.893421901020044	0.78868375646155	1
GO:0050699	WW domain binding	4/4017	24/18639	0.166666666666667	0.773338312173264	0.792429960163933	1
GO:0070300	phosphatidic acid binding	4/4017	24/18639	0.166666666666667	0.773338312173264	0.792429960163933	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/4017	24/18639	0.166666666666667	0.773338312173264	0.792429960163933	1
GO:0004676	3-phosphoinositide-dependent protein kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0004711	ribosomal protein S6 kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0035175	histone H3S10 kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0035979	histone H2AXS139 kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0044022	histone H3S28 kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0044023	histone H4S1 kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0044024	histone H2AS1 kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0044025	histone H2BS14 kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0072354	histone H3T3 kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0072371	histone H2AS121 kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0072518	Rho-dependent protein serine/threonine kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0140823	histone H2BS36 kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0140855	histone H3S57 kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0140995	histone H2A kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0140997	histone H4 kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0140998	histone H2B kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:1990244	histone H2AT120 kinase activity	48/4017	245/18639	0.195918367346939	0.909067077166938	0.795219150500977	1
GO:0019212	phosphatase inhibitor activity	10/4017	56/18639	0.178571428571429	0.828576763042782	0.795799487568917	1
GO:0004623	phospholipase A2 activity	6/4017	35/18639	0.171428571428571	0.795433692521071	0.796379759420674	1
GO:0015085	calcium ion transmembrane transporter activity	28/4017	147/18639	0.19047619047619	0.883815213912301	0.798562982692854	1
GO:0004677	DNA-dependent protein kinase activity	48/4017	246/18639	0.195121951219512	0.905371682544309	0.804408558884954	1
GO:0004180	carboxypeptidase activity	8/4017	46/18639	0.173913043478261	0.806961717050362	0.804584752583394	1
GO:0003964	RNA-directed DNA polymerase activity	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0005035	death receptor activity	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0019855	calcium channel inhibitor activity	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0030955	potassium ion binding	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0031432	titin binding	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0043560	insulin receptor substrate binding	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0045159	myosin II binding	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0046975	histone H3K36 methyltransferase activity	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0051011	microtubule minus-end binding	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0089720	caspase binding	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0097157	pre-mRNA intronic binding	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:1901338	catecholamine binding	2/4017	13/18639	0.153846153846154	0.713850749698397	0.805274679464853	1
GO:0032452	histone demethylase activity	5/4017	30/18639	0.166666666666667	0.773338312173264	0.805982805876951	1
GO:0005516	calmodulin binding	40/4017	207/18639	0.193236714975845	0.896624130055958	0.806514485266681	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	3/4017	19/18639	0.157894736842105	0.732636295743092	0.810157536293421	1
GO:0008381	mechanosensitive monoatomic ion channel activity	3/4017	19/18639	0.157894736842105	0.732636295743092	0.810157536293421	1
GO:0022840	leak channel activity	3/4017	19/18639	0.157894736842105	0.732636295743092	0.810157536293421	1
GO:0022842	narrow pore channel activity	3/4017	19/18639	0.157894736842105	0.732636295743092	0.810157536293421	1
GO:0030506	ankyrin binding	3/4017	19/18639	0.157894736842105	0.732636295743092	0.810157536293421	1
GO:0042800	histone H3K4 methyltransferase activity	3/4017	19/18639	0.157894736842105	0.732636295743092	0.810157536293421	1
GO:0043395	heparan sulfate proteoglycan binding	3/4017	19/18639	0.157894736842105	0.732636295743092	0.810157536293421	1
GO:0001530	lipopolysaccharide binding	7/4017	41/18639	0.170731707317073	0.79220022222627	0.81079877877027	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	7/4017	41/18639	0.170731707317073	0.79220022222627	0.81079877877027	1
GO:0035402	histone H3T11 kinase activity	48/4017	247/18639	0.194331983805668	0.901706210145344	0.813317020763339	1
GO:0001848	complement binding	4/4017	25/18639	0.16	0.742404779686333	0.819129210199296	1
GO:0015645	fatty acid ligase activity	4/4017	25/18639	0.16	0.742404779686333	0.819129210199296	1
GO:0015662	P-type ion transporter activity	4/4017	25/18639	0.16	0.742404779686333	0.819129210199296	1
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	4/4017	25/18639	0.16	0.742404779686333	0.819129210199296	1
GO:0120020	cholesterol transfer activity	4/4017	25/18639	0.16	0.742404779686333	0.819129210199296	1
GO:0120515	fatty acid-CoA ligase activity	4/4017	25/18639	0.16	0.742404779686333	0.819129210199296	1
GO:0140358	P-type transmembrane transporter activity	4/4017	25/18639	0.16	0.742404779686333	0.819129210199296	1
GO:0004679	AMP-activated protein kinase activity	48/4017	248/18639	0.193548387096774	0.898070298007661	0.82194474645412	1
GO:0070325	lipoprotein particle receptor binding	5/4017	31/18639	0.161290322580645	0.748391915006384	0.829130876792967	1
GO:0042056	chemoattractant activity	7/4017	42/18639	0.166666666666667	0.773338312173264	0.830649802758205	1
GO:0004864	protein phosphatase inhibitor activity	9/4017	53/18639	0.169811320754717	0.787929601082193	0.835782682569044	1
GO:0016505	peptidase activator activity involved in apoptotic process	3/4017	20/18639	0.15	0.696004480955937	0.837790531974184	1
GO:0042288	MHC class I protein binding	3/4017	20/18639	0.15	0.696004480955937	0.837790531974184	1
GO:0008494	translation activator activity	2/4017	14/18639	0.142857142857143	0.662861410434226	0.838081470879242	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	2/4017	14/18639	0.142857142857143	0.662861410434226	0.838081470879242	1
GO:0032036	myosin heavy chain binding	2/4017	14/18639	0.142857142857143	0.662861410434226	0.838081470879242	1
GO:0032454	histone H3K9 demethylase activity	2/4017	14/18639	0.142857142857143	0.662861410434226	0.838081470879242	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/4017	14/18639	0.142857142857143	0.662861410434226	0.838081470879242	1
GO:1901474	azole transmembrane transporter activity	2/4017	14/18639	0.142857142857143	0.662861410434226	0.838081470879242	1
GO:0022829	wide pore channel activity	6/4017	37/18639	0.162162162162162	0.752437276709121	0.839152584547805	1
GO:0042805	actinin binding	6/4017	37/18639	0.162162162162162	0.752437276709121	0.839152584547805	1
GO:0043394	proteoglycan binding	6/4017	37/18639	0.162162162162162	0.752437276709121	0.839152584547805	1
GO:0005112	Notch binding	4/4017	26/18639	0.153846153846154	0.713850749698397	0.842928241583684	1
GO:0005160	transforming growth factor beta receptor binding	4/4017	26/18639	0.153846153846154	0.713850749698397	0.842928241583684	1
GO:0070412	R-SMAD binding	4/4017	26/18639	0.153846153846154	0.713850749698397	0.842928241583684	1
GO:0036002	pre-mRNA binding	10/4017	59/18639	0.169491525423729	0.786445741193149	0.84667001399757	1
GO:0047498	calcium-dependent phospholipase A2 activity	5/4017	32/18639	0.15625	0.725004667662435	0.849978036389388	1
GO:0020037	heme binding	26/4017	142/18639	0.183098591549296	0.849582934500205	0.852682037565463	1
GO:0038024	cargo receptor activity	11/4017	65/18639	0.169230769230769	0.785235824668237	0.856657589704445	1
GO:1990782	protein tyrosine kinase binding	21/4017	117/18639	0.179487179487179	0.83282587464813	0.857076305463495	1
GO:0016247	channel regulator activity	31/4017	168/18639	0.18452380952381	0.856195988477542	0.859727552970579	1
GO:0008373	sialyltransferase activity	3/4017	21/18639	0.142857142857143	0.662861410434226	0.861874645688224	1
GO:0019200	carbohydrate kinase activity	3/4017	21/18639	0.142857142857143	0.662861410434226	0.861874645688224	1
GO:0008395	steroid hydroxylase activity	4/4017	27/18639	0.148148148148148	0.687411833042901	0.864031099365444	1
GO:0016405	CoA-ligase activity	4/4017	27/18639	0.148148148148148	0.687411833042901	0.864031099365444	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/4017	27/18639	0.148148148148148	0.687411833042901	0.864031099365444	1
GO:0023026	MHC class II protein complex binding	4/4017	27/18639	0.148148148148148	0.687411833042901	0.864031099365444	1
GO:0005041	low-density lipoprotein particle receptor activity	2/4017	15/18639	0.133333333333333	0.618670649738611	0.865795672700199	1
GO:0042809	nuclear vitamin D receptor binding	2/4017	15/18639	0.133333333333333	0.618670649738611	0.865795672700199	1
GO:0047372	monoacylglycerol lipase activity	2/4017	15/18639	0.133333333333333	0.618670649738611	0.865795672700199	1
GO:0051371	muscle alpha-actinin binding	2/4017	15/18639	0.133333333333333	0.618670649738611	0.865795672700199	1
GO:0098632	cell-cell adhesion mediator activity	9/4017	55/18639	0.163636363636364	0.759277615588295	0.866593900524088	1
GO:0019956	chemokine binding	5/4017	33/18639	0.151515151515152	0.703034829248421	0.868666197945162	1
GO:0141108	transporter regulator activity	31/4017	170/18639	0.182352941176471	0.846123094495453	0.87631618459402	1
GO:0050840	extracellular matrix binding	11/4017	67/18639	0.164179104477612	0.761795949305006	0.882214001024316	1
GO:0051119	sugar transmembrane transporter activity	4/4017	28/18639	0.142857142857143	0.662861410434226	0.882652993753496	1
GO:0051393	alpha-actinin binding	4/4017	28/18639	0.142857142857143	0.662861410434226	0.882652993753496	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	5/4017	34/18639	0.147058823529412	0.682357334270527	0.885346497554825	1
GO:0016597	amino acid binding	8/4017	51/18639	0.156862745098039	0.727847823221895	0.886539840826116	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/4017	16/18639	0.125	0.580003734129948	0.88908801290652	1
GO:0015385	sodium:proton antiporter activity	2/4017	16/18639	0.125	0.580003734129948	0.88908801290652	1
GO:0019841	retinol binding	2/4017	16/18639	0.125	0.580003734129948	0.88908801290652	1
GO:0022841	potassium ion leak channel activity	2/4017	16/18639	0.125	0.580003734129948	0.88908801290652	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	2/4017	16/18639	0.125	0.580003734129948	0.88908801290652	1
GO:0015144	carbohydrate transmembrane transporter activity	6/4017	40/18639	0.15	0.696004480955937	0.889373108172139	1
GO:0005262	calcium channel activity	23/4017	131/18639	0.175572519083969	0.81466173343443	0.891415958709163	1
GO:0001217	DNA-binding transcription repressor activity	52/4017	278/18639	0.18705035971223	0.867919256827548	0.893340367550694	1
GO:0046906	tetrapyrrole binding	27/4017	152/18639	0.177631578947368	0.824215832710978	0.894572180884154	1
GO:0033293	monocarboxylic acid binding	13/4017	79/18639	0.164556962025316	0.763549219614108	0.895854508491636	1
GO:1901682	sulfur compound transmembrane transporter activity	10/4017	63/18639	0.158730158730159	0.736512678260251	0.898369191192882	1
GO:0004629	phospholipase C activity	4/4017	29/18639	0.137931034482759	0.640004120419253	0.89901232447135	1
GO:0035250	UDP-galactosyltransferase activity	4/4017	29/18639	0.137931034482759	0.640004120419253	0.89901232447135	1
GO:0004497	monooxygenase activity	18/4017	106/18639	0.169811320754717	0.787929601082193	0.90011937595612	1
GO:0016849	phosphorus-oxygen lyase activity	3/4017	23/18639	0.130434782608696	0.605221287787772	0.900770947204849	1
GO:0070577	lysine-acetylated histone binding	3/4017	23/18639	0.130434782608696	0.605221287787772	0.900770947204849	1
GO:0051015	actin filament binding	38/4017	209/18639	0.181818181818182	0.843641795098106	0.901006100695002	1
GO:0017080	sodium channel regulator activity	6/4017	41/18639	0.146341463414634	0.679028761908231	0.90284299321246	1
GO:0005504	fatty acid binding	7/4017	47/18639	0.148936170212766	0.691068278963342	0.906299936953119	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/4017	17/18639	0.117647058823529	0.545885867416421	0.908576717167356	1
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/4017	17/18639	0.117647058823529	0.545885867416421	0.908576717167356	1
GO:0019198	transmembrane receptor protein phosphatase activity	2/4017	17/18639	0.117647058823529	0.545885867416421	0.908576717167356	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/4017	17/18639	0.117647058823529	0.545885867416421	0.908576717167356	1
GO:0036041	long-chain fatty acid binding	2/4017	17/18639	0.117647058823529	0.545885867416421	0.908576717167356	1
GO:0045236	CXCR chemokine receptor binding	2/4017	17/18639	0.117647058823529	0.545885867416421	0.908576717167356	1
GO:0001094	TFIID-class transcription factor complex binding	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0004935	adrenergic receptor activity	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0005131	growth hormone receptor binding	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0008190	eukaryotic initiation factor 4E binding	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0015187	glycine transmembrane transporter activity	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0015643	toxic substance binding	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0031419	cobalamin binding	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0031434	mitogen-activated protein kinase kinase binding	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0031720	haptoglobin binding	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0032395	MHC class II receptor activity	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0051378	serotonin binding	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0070097	delta-catenin binding	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0071723	lipopeptide binding	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:1990763	arrestin family protein binding	1/4017	10/18639	0.1	0.464002987303958	0.911782742953234	1
GO:0004190	aspartic-type endopeptidase activity	5/4017	36/18639	0.138888888888889	0.64444859347772	0.913305089412615	1
GO:0019894	kinesin binding	6/4017	42/18639	0.142857142857143	0.662861410434226	0.914875191621502	1
GO:0004806	triacylglycerol lipase activity	3/4017	24/18639	0.125	0.580003734129948	0.916248231067837	1
GO:0015149	hexose transmembrane transporter activity	3/4017	24/18639	0.125	0.580003734129948	0.916248231067837	1
GO:0019957	C-C chemokine binding	3/4017	24/18639	0.125	0.580003734129948	0.916248231067837	1
GO:0030215	semaphorin receptor binding	3/4017	24/18639	0.125	0.580003734129948	0.916248231067837	1
GO:0055056	D-glucose transmembrane transporter activity	3/4017	24/18639	0.125	0.580003734129948	0.916248231067837	1
GO:0070840	dynein complex binding	3/4017	24/18639	0.125	0.580003734129948	0.916248231067837	1
GO:0140033	acetylation-dependent protein binding	3/4017	24/18639	0.125	0.580003734129948	0.916248231067837	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	7/4017	48/18639	0.145833333333333	0.676671023151606	0.917337355117425	1
GO:0098631	cell adhesion mediator activity	12/4017	76/18639	0.157894736842105	0.732636295743092	0.918040800925251	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	49/4017	268/18639	0.182835820895522	0.848363670816939	0.919179510567684	1
GO:0015297	antiporter activity	23/4017	135/18639	0.17037037037037	0.790523607999336	0.920222973270859	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	9/4017	60/18639	0.15	0.696004480955937	0.923510780162901	1
GO:0004706	JUN kinase kinase kinase activity	2/4017	18/18639	0.111111111111111	0.515558874782176	0.924818982879102	1
GO:0022851	GABA-gated chloride ion channel activity	2/4017	18/18639	0.111111111111111	0.515558874782176	0.924818982879102	1
GO:0030228	lipoprotein particle receptor activity	2/4017	18/18639	0.111111111111111	0.515558874782176	0.924818982879102	1
GO:0023023	MHC protein complex binding	5/4017	37/18639	0.135135135135135	0.627031063924268	0.924891418297742	1
GO:0070001	aspartic-type peptidase activity	5/4017	37/18639	0.135135135135135	0.627031063924268	0.924891418297742	1
GO:0005452	solute:inorganic anion antiporter activity	4/4017	31/18639	0.129032258064516	0.598713532005107	0.925797696072856	1
GO:0015631	tubulin binding	72/4017	385/18639	0.187012987012987	0.867745846386623	0.926520358293488	1
GO:0042974	nuclear retinoic acid receptor binding	3/4017	25/18639	0.12	0.55680358476475	0.929491733913547	1
GO:0042562	hormone binding	15/4017	94/18639	0.159574468085106	0.740430298889295	0.930514677285081	1
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0001851	complement component C3b binding	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0002162	dystroglycan binding	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0004016	adenylate cyclase activity	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0005114	type II transforming growth factor beta receptor binding	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0005225	volume-sensitive anion channel activity	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0008046	axon guidance receptor activity	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0008172	S-methyltransferase activity	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0008199	ferric iron binding	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0008432	JUN kinase binding	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0016594	glycine binding	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0032794	GTPase activating protein binding	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0050786	RAGE receptor binding	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0070697	activin receptor binding	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/4017	11/18639	0.0909090909090909	0.421820897549053	0.930805166140569	1
GO:0015026	coreceptor activity	9/4017	61/18639	0.147540983606557	0.684594571432069	0.931964665188773	1
GO:0005096	GTPase activator activity	49/4017	271/18639	0.180811808118081	0.838972191066197	0.932153969221308	1
GO:0005017	platelet-derived growth factor receptor activity	7/4017	50/18639	0.14	0.649604182225542	0.936072704194363	1
GO:0005019	platelet-derived growth factor beta-receptor activity	7/4017	50/18639	0.14	0.649604182225542	0.936072704194363	1
GO:0071813	lipoprotein particle binding	4/4017	32/18639	0.125	0.580003734129948	0.936629076027637	1
GO:0071814	protein-lipid complex binding	4/4017	32/18639	0.125	0.580003734129948	0.936629076027637	1
GO:0004890	GABA-A receptor activity	2/4017	19/18639	0.105263157894737	0.488424197162061	0.938308564830359	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/4017	19/18639	0.105263157894737	0.488424197162061	0.938308564830359	1
GO:0008301	DNA binding, bending	2/4017	19/18639	0.105263157894737	0.488424197162061	0.938308564830359	1
GO:0015245	fatty acid transmembrane transporter activity	2/4017	19/18639	0.105263157894737	0.488424197162061	0.938308564830359	1
GO:0016918	retinal binding	2/4017	19/18639	0.105263157894737	0.488424197162061	0.938308564830359	1
GO:0031420	alkali metal ion binding	2/4017	19/18639	0.105263157894737	0.488424197162061	0.938308564830359	1
GO:0141147	intracellularly calcium-gated channel activity	2/4017	19/18639	0.105263157894737	0.488424197162061	0.938308564830359	1
GO:0015179	L-amino acid transmembrane transporter activity	9/4017	62/18639	0.145161290322581	0.673552723505746	0.939595479678669	1
GO:0004435	phosphatidylinositol phospholipase C activity	3/4017	26/18639	0.115384615384615	0.535388062273798	0.940782624217443	1
GO:0015145	monosaccharide transmembrane transporter activity	3/4017	26/18639	0.115384615384615	0.535388062273798	0.940782624217443	1
GO:0043548	phosphatidylinositol 3-kinase binding	3/4017	26/18639	0.115384615384615	0.535388062273798	0.940782624217443	1
GO:0099106	ion channel regulator activity	27/4017	160/18639	0.16875	0.783005041075429	0.941818955871145	1
GO:0042605	peptide antigen binding	6/4017	45/18639	0.133333333333333	0.618670649738611	0.943507399562692	1
GO:0060589	nucleoside-triphosphatase regulator activity	92/4017	490/18639	0.187755102040816	0.871189282284983	0.943649264059508	1
GO:0005021	vascular endothelial growth factor receptor activity	7/4017	51/18639	0.137254901960784	0.636866845319158	0.943952932457494	1
GO:0004000	adenosine deaminase activity	1/4017	12/18639	0.0833333333333333	0.386669156086632	0.945726555855693	1
GO:0004032	aldose reductase (NADPH) activity	1/4017	12/18639	0.0833333333333333	0.386669156086632	0.945726555855693	1
GO:0005025	transforming growth factor beta receptor activity, type I	1/4017	12/18639	0.0833333333333333	0.386669156086632	0.945726555855693	1
GO:0005026	transforming growth factor beta receptor activity, type II	1/4017	12/18639	0.0833333333333333	0.386669156086632	0.945726555855693	1
GO:0005165	neurotrophin receptor binding	1/4017	12/18639	0.0833333333333333	0.386669156086632	0.945726555855693	1
GO:0005247	voltage-gated chloride channel activity	1/4017	12/18639	0.0833333333333333	0.386669156086632	0.945726555855693	1
GO:0008504	monoamine transmembrane transporter activity	1/4017	12/18639	0.0833333333333333	0.386669156086632	0.945726555855693	1
GO:0016361	activin receptor activity, type I	1/4017	12/18639	0.0833333333333333	0.386669156086632	0.945726555855693	1
GO:0016362	activin receptor activity, type II	1/4017	12/18639	0.0833333333333333	0.386669156086632	0.945726555855693	1
GO:0016840	carbon-nitrogen lyase activity	1/4017	12/18639	0.0833333333333333	0.386669156086632	0.945726555855693	1
GO:0017002	activin receptor activity	1/4017	12/18639	0.0833333333333333	0.386669156086632	0.945726555855693	1
GO:0035259	nuclear glucocorticoid receptor binding	1/4017	12/18639	0.0833333333333333	0.386669156086632	0.945726555855693	1
GO:0070410	co-SMAD binding	1/4017	12/18639	0.0833333333333333	0.386669156086632	0.945726555855693	1
GO:0030246	carbohydrate binding	50/4017	280/18639	0.178571428571429	0.828576763042782	0.946420845616801	1
GO:0001614	purinergic nucleotide receptor activity	2/4017	20/18639	0.1	0.464002987303958	0.949477235147712	1
GO:0005326	neurotransmitter transmembrane transporter activity	2/4017	20/18639	0.1	0.464002987303958	0.949477235147712	1
GO:0016502	nucleotide receptor activity	2/4017	20/18639	0.1	0.464002987303958	0.949477235147712	1
GO:0030159	signaling receptor complex adaptor activity	7/4017	52/18639	0.134615384615385	0.624619405986098	0.950957184123581	1
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	5/4017	40/18639	0.125	0.580003734129948	0.951817373342857	1
GO:0015101	organic cation transmembrane transporter activity	12/4017	81/18639	0.148148148148148	0.687411833042901	0.951964620149808	1
GO:0030695	GTPase regulator activity	91/4017	489/18639	0.186094069529652	0.863482041813092	0.953361188771435	1
GO:0019825	oxygen binding	4/4017	34/18639	0.117647058823529	0.545885867416421	0.954090835248399	1
GO:0005003	ephrin receptor activity	7/4017	53/18639	0.132075471698113	0.612834134175039	0.95716681963309	1
GO:0005005	transmembrane-ephrin receptor activity	7/4017	53/18639	0.132075471698113	0.612834134175039	0.95716681963309	1
GO:0004465	lipoprotein lipase activity	1/4017	13/18639	0.0769230769230769	0.356925374849199	0.957430878888263	1
GO:0004993	G protein-coupled serotonin receptor activity	1/4017	13/18639	0.0769230769230769	0.356925374849199	0.957430878888263	1
GO:0005542	folic acid binding	1/4017	13/18639	0.0769230769230769	0.356925374849199	0.957430878888263	1
GO:0017154	semaphorin receptor activity	1/4017	13/18639	0.0769230769230769	0.356925374849199	0.957430878888263	1
GO:0035325	Toll-like receptor binding	1/4017	13/18639	0.0769230769230769	0.356925374849199	0.957430878888263	1
GO:0070123	transforming growth factor beta receptor activity, type III	1/4017	13/18639	0.0769230769230769	0.356925374849199	0.957430878888263	1
GO:0071714	icosanoid transmembrane transporter activity	1/4017	13/18639	0.0769230769230769	0.356925374849199	0.957430878888263	1
GO:0071837	HMG box domain binding	1/4017	13/18639	0.0769230769230769	0.356925374849199	0.957430878888263	1
GO:0140333	glycerophospholipid flippase activity	1/4017	13/18639	0.0769230769230769	0.356925374849199	0.957430878888263	1
GO:0001727	lipid kinase activity	5/4017	41/18639	0.121951219512195	0.565857301590193	0.95861937058319	1
GO:0042169	SH2 domain binding	5/4017	41/18639	0.121951219512195	0.565857301590193	0.95861937058319	1
GO:0042287	MHC protein binding	5/4017	41/18639	0.121951219512195	0.565857301590193	0.95861937058319	1
GO:0015125	bile acid transmembrane transporter activity	2/4017	21/18639	0.0952380952380952	0.441907606956151	0.958698560353974	1
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/4017	21/18639	0.0952380952380952	0.441907606956151	0.958698560353974	1
GO:0051428	peptide hormone receptor binding	2/4017	21/18639	0.0952380952380952	0.441907606956151	0.958698560353974	1
GO:0008514	organic anion transmembrane transporter activity	47/4017	269/18639	0.174721189591078	0.810711539155615	0.959409041658986	1
GO:0008013	beta-catenin binding	16/4017	106/18639	0.150943396226415	0.700381867628616	0.963680925699874	1
GO:0004181	metallocarboxypeptidase activity	3/4017	29/18639	0.103448275862069	0.480003090314439	0.965367747454055	1
GO:0043236	laminin binding	3/4017	29/18639	0.103448275862069	0.480003090314439	0.965367747454055	1
GO:0005243	gap junction channel activity	2/4017	22/18639	0.0909090909090909	0.421820897549053	0.966292929383214	1
GO:0016881	acid-amino acid ligase activity	2/4017	22/18639	0.0909090909090909	0.421820897549053	0.966292929383214	1
GO:0033038	bitter taste receptor activity	2/4017	22/18639	0.0909090909090909	0.421820897549053	0.966292929383214	1
GO:0005344	oxygen carrier activity	1/4017	14/18639	0.0714285714285714	0.331430705217113	0.966611602581265	1
GO:0015926	glucosidase activity	1/4017	14/18639	0.0714285714285714	0.331430705217113	0.966611602581265	1
GO:0031404	chloride ion binding	1/4017	14/18639	0.0714285714285714	0.331430705217113	0.966611602581265	1
GO:0098821	BMP receptor activity	1/4017	14/18639	0.0714285714285714	0.331430705217113	0.966611602581265	1
GO:0005004	GPI-linked ephrin receptor activity	6/4017	49/18639	0.122448979591837	0.568166923229336	0.968211147375946	1
GO:0005008	hepatocyte growth factor receptor activity	6/4017	49/18639	0.122448979591837	0.568166923229336	0.968211147375946	1
GO:0005009	insulin receptor activity	6/4017	49/18639	0.122448979591837	0.568166923229336	0.968211147375946	1
GO:0005011	macrophage colony-stimulating factor receptor activity	6/4017	49/18639	0.122448979591837	0.568166923229336	0.968211147375946	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	6/4017	49/18639	0.122448979591837	0.568166923229336	0.968211147375946	1
GO:0005020	stem cell factor receptor activity	6/4017	49/18639	0.122448979591837	0.568166923229336	0.968211147375946	1
GO:0008288	boss receptor activity	6/4017	49/18639	0.122448979591837	0.568166923229336	0.968211147375946	1
GO:0036332	placental growth factor receptor activity	6/4017	49/18639	0.122448979591837	0.568166923229336	0.968211147375946	1
GO:0038062	protein tyrosine kinase collagen receptor activity	6/4017	49/18639	0.122448979591837	0.568166923229336	0.968211147375946	1
GO:0060175	brain-derived neurotrophic factor receptor activity	6/4017	49/18639	0.122448979591837	0.568166923229336	0.968211147375946	1
GO:0001965	G-protein alpha-subunit binding	3/4017	30/18639	0.1	0.464002987303958	0.97115032404881	1
GO:0048019	receptor antagonist activity	3/4017	30/18639	0.1	0.464002987303958	0.97115032404881	1
GO:0098918	structural constituent of synapse	3/4017	30/18639	0.1	0.464002987303958	0.97115032404881	1
GO:0170055	lipid transmembrane transporter activity	7/4017	56/18639	0.125	0.580003734129948	0.971768229580409	1
GO:0030551	cyclic nucleotide binding	4/4017	37/18639	0.108108108108108	0.501624851139414	0.972121616532705	1
GO:0016493	C-C chemokine receptor activity	2/4017	23/18639	0.0869565217391304	0.403480858525181	0.972533118162106	1
GO:0016917	GABA receptor activity	2/4017	23/18639	0.0869565217391304	0.403480858525181	0.972533118162106	1
GO:0043274	phospholipase binding	2/4017	23/18639	0.0869565217391304	0.403480858525181	0.972533118162106	1
GO:0099186	structural constituent of postsynapse	2/4017	23/18639	0.0869565217391304	0.403480858525181	0.972533118162106	1
GO:0005006	epidermal growth factor receptor activity	6/4017	50/18639	0.12	0.55680358476475	0.972593662355253	1
GO:0005007	fibroblast growth factor receptor activity	6/4017	50/18639	0.12	0.55680358476475	0.972593662355253	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/4017	15/18639	0.0666666666666667	0.309335324869305	0.973812740429912	1
GO:0005523	tropomyosin binding	1/4017	15/18639	0.0666666666666667	0.309335324869305	0.973812740429912	1
GO:0008020	G protein-coupled photoreceptor activity	1/4017	15/18639	0.0666666666666667	0.309335324869305	0.973812740429912	1
GO:0015250	water channel activity	1/4017	15/18639	0.0666666666666667	0.309335324869305	0.973812740429912	1
GO:0017081	chloride channel regulator activity	1/4017	15/18639	0.0666666666666667	0.309335324869305	0.973812740429912	1
GO:0030553	cGMP binding	1/4017	15/18639	0.0666666666666667	0.309335324869305	0.973812740429912	1
GO:0033130	acetylcholine receptor binding	1/4017	15/18639	0.0666666666666667	0.309335324869305	0.973812740429912	1
GO:0045504	dynein heavy chain binding	1/4017	15/18639	0.0666666666666667	0.309335324869305	0.973812740429912	1
GO:0120283	protein serine/threonine kinase binding	1/4017	15/18639	0.0666666666666667	0.309335324869305	0.973812740429912	1
GO:0030547	signaling receptor inhibitor activity	5/4017	44/18639	0.113636363636364	0.527276121936316	0.974085613723738	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	3/4017	31/18639	0.0967741935483871	0.449035149003831	0.976009534189091	1
GO:0005010	insulin-like growth factor receptor activity	6/4017	51/18639	0.117647058823529	0.545885867416421	0.976412426341621	1
GO:0005030	neurotrophin receptor activity	6/4017	51/18639	0.117647058823529	0.545885867416421	0.976412426341621	1
GO:0030552	cAMP binding	2/4017	24/18639	0.0833333333333333	0.386669156086632	0.977649926079766	1
GO:0005024	transforming growth factor beta receptor activity	1/4017	16/18639	0.0625	0.290001867064974	0.979461055598138	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/4017	16/18639	0.0625	0.290001867064974	0.979461055598138	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/4017	16/18639	0.0625	0.290001867064974	0.979461055598138	1
GO:0001540	amyloid-beta binding	11/4017	83/18639	0.132530120481928	0.61494371811368	0.980839475512961	1
GO:0004867	serine-type endopeptidase inhibitor activity	13/4017	95/18639	0.136842105263158	0.63495145631068	0.981417373469599	1
GO:0004709	MAP kinase kinase kinase activity	2/4017	25/18639	0.08	0.371202389843167	0.981837594963785	1
GO:0005251	delayed rectifier potassium channel activity	2/4017	25/18639	0.08	0.371202389843167	0.981837594963785	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/4017	25/18639	0.08	0.371202389843167	0.981837594963785	1
GO:0038064	collagen receptor activity	6/4017	53/18639	0.113207547169811	0.525286400721462	0.982613422861922	1
GO:0019199	transmembrane receptor protein kinase activity	10/4017	78/18639	0.128205128205128	0.594875624748664	0.983087011241563	1
GO:0030296	protein tyrosine kinase activator activity	3/4017	33/18639	0.0909090909090909	0.421820897549053	0.983491385546609	1
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/4017	17/18639	0.0588235294117647	0.272942933708211	0.983891326750062	1
GO:0008569	minus-end-directed microtubule motor activity	1/4017	17/18639	0.0588235294117647	0.272942933708211	0.983891326750062	1
GO:0009881	photoreceptor activity	1/4017	17/18639	0.0588235294117647	0.272942933708211	0.983891326750062	1
GO:0015278	intracellularly gated calcium channel activity	1/4017	17/18639	0.0588235294117647	0.272942933708211	0.983891326750062	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/4017	17/18639	0.0588235294117647	0.272942933708211	0.983891326750062	1
GO:0045125	bioactive lipid receptor activity	1/4017	17/18639	0.0588235294117647	0.272942933708211	0.983891326750062	1
GO:0099095	ligand-gated monoatomic anion channel activity	5/4017	47/18639	0.106382978723404	0.49362019925953	0.98402368421813	1
GO:0001637	G protein-coupled chemoattractant receptor activity	2/4017	26/18639	0.0769230769230769	0.356925374849199	0.985258842525981	1
GO:0004950	chemokine receptor activity	2/4017	26/18639	0.0769230769230769	0.356925374849199	0.985258842525981	1
GO:0005227	calcium-activated cation channel activity	2/4017	26/18639	0.0769230769230769	0.356925374849199	0.985258842525981	1
GO:0030507	spectrin binding	2/4017	26/18639	0.0769230769230769	0.356925374849199	0.985258842525981	1
GO:0031406	carboxylic acid binding	29/4017	187/18639	0.155080213903743	0.719576825230737	0.985285008564749	1
GO:0005253	monoatomic anion channel activity	14/4017	103/18639	0.135922330097087	0.630683672063633	0.985624023895422	1
GO:0051427	hormone receptor binding	3/4017	34/18639	0.0882352941176471	0.409414400562316	0.986336600091598	1
GO:0061134	peptidase regulator activity	36/4017	226/18639	0.15929203539823	0.739119802785066	0.986569830209136	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/4017	18/18639	0.0555555555555556	0.257779437391088	0.987366170507177	1
GO:0004970	glutamate-gated receptor activity	1/4017	18/18639	0.0555555555555556	0.257779437391088	0.987366170507177	1
GO:0005372	water transmembrane transporter activity	1/4017	18/18639	0.0555555555555556	0.257779437391088	0.987366170507177	1
GO:0032393	MHC class I receptor activity	1/4017	18/18639	0.0555555555555556	0.257779437391088	0.987366170507177	1
GO:0050811	GABA receptor binding	1/4017	18/18639	0.0555555555555556	0.257779437391088	0.987366170507177	1
GO:0005126	cytokine receptor binding	45/4017	275/18639	0.163636363636364	0.759277615588295	0.987484683590857	1
GO:0043177	organic acid binding	29/4017	189/18639	0.153439153439153	0.711962255651576	0.987733367216507	1
GO:0003779	actin binding	77/4017	443/18639	0.173814898419865	0.806506321047512	0.988253639131831	1
GO:0061135	endopeptidase regulator activity	28/4017	184/18639	0.152173913043478	0.706091502419067	0.988286073446949	1
GO:0031490	chromatin DNA binding	18/4017	128/18639	0.140625	0.652504200896191	0.988385251021936	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/4017	19/18639	0.0526315789473684	0.244212098581031	0.990091593044778	1
GO:0042834	peptidoglycan binding	1/4017	19/18639	0.0526315789473684	0.244212098581031	0.990091593044778	1
GO:0099589	serotonin receptor activity	1/4017	19/18639	0.0526315789473684	0.244212098581031	0.990091593044778	1
GO:0008527	taste receptor activity	2/4017	28/18639	0.0714285714285714	0.331430705217113	0.990322196387509	1
GO:0051959	dynein light intermediate chain binding	2/4017	28/18639	0.0714285714285714	0.331430705217113	0.990322196387509	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/4017	36/18639	0.0833333333333333	0.386669156086632	0.990679403792158	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	8/4017	70/18639	0.114285714285714	0.530289128347381	0.990766069667802	1
GO:0003774	cytoskeletal motor activity	22/4017	153/18639	0.143790849673203	0.667193837953404	0.990837922587088	1
GO:0005416	amino acid:monoatomic cation symporter activity	2/4017	29/18639	0.0689655172413793	0.320002060209626	0.992170674086283	1
GO:0099604	ligand-gated calcium channel activity	2/4017	29/18639	0.0689655172413793	0.320002060209626	0.992170674086283	1
GO:0004896	cytokine receptor activity	12/4017	96/18639	0.125	0.580003734129948	0.992177221264568	1
GO:0001972	retinoic acid binding	1/4017	20/18639	0.05	0.232001493651979	0.992229190828835	1
GO:0015464	acetylcholine receptor activity	1/4017	20/18639	0.05	0.232001493651979	0.992229190828835	1
GO:0030627	pre-mRNA 5'-splice site binding	1/4017	20/18639	0.05	0.232001493651979	0.992229190828835	1
GO:0022839	monoatomic ion-gated channel activity	2/4017	30/18639	0.0666666666666667	0.309335324869305	0.993672127660389	1
GO:0005501	retinoid binding	3/4017	38/18639	0.0789473684210526	0.366318147871546	0.993674350875334	1
GO:0019840	isoprenoid binding	3/4017	38/18639	0.0789473684210526	0.366318147871546	0.993674350875334	1
GO:0005248	voltage-gated sodium channel activity	1/4017	21/18639	0.0476190476190476	0.220953803478075	0.993905722352578	1
GO:0015174	basic amino acid transmembrane transporter activity	1/4017	21/18639	0.0476190476190476	0.220953803478075	0.993905722352578	1
GO:0017046	peptide hormone binding	5/4017	53/18639	0.0943396226415094	0.437738667267885	0.994168889027807	1
GO:0016500	protein-hormone receptor activity	7/4017	67/18639	0.104477611940299	0.484779240466822	0.994563925504008	1
GO:0005539	glycosaminoglycan binding	37/4017	242/18639	0.152892561983471	0.709426054968862	0.994631979994422	1
GO:0015377	chloride:monoatomic cation symporter activity	1/4017	22/18639	0.0454545454545455	0.210910448774526	0.995220617255881	1
GO:0033691	sialic acid binding	1/4017	22/18639	0.0454545454545455	0.210910448774526	0.995220617255881	1
GO:0015106	bicarbonate transmembrane transporter activity	2/4017	32/18639	0.0625	0.290001867064974	0.995877361746055	1
GO:0008201	heparin binding	24/4017	172/18639	0.13953488372093	0.647446028796221	0.995903678158966	1
GO:0005283	amino acid:sodium symporter activity	1/4017	23/18639	0.0434782608695652	0.201740429262591	0.996251867214689	1
GO:0015171	amino acid transmembrane transporter activity	12/4017	102/18639	0.117647058823529	0.545885867416421	0.996490277146429	1
GO:0008017	microtubule binding	42/4017	276/18639	0.152173913043478	0.706091502419067	0.997016872081542	1
GO:0015291	secondary active transmembrane transporter activity	44/4017	287/18639	0.153310104529617	0.711363464856242	0.997026210133159	1
GO:0017171	serine hydrolase activity	28/4017	198/18639	0.141414141414141	0.65616584063186	0.997061965549365	1
GO:0008307	structural constituent of muscle	3/4017	42/18639	0.0714285714285714	0.331430705217113	0.997125640621769	1
GO:0004252	serine-type endopeptidase activity	24/4017	176/18639	0.136363636363636	0.632731346323579	0.997350731057259	1
GO:0008236	serine-type peptidase activity	27/4017	194/18639	0.139175257731959	0.645777353464272	0.997546841688725	1
GO:0015271	outward rectifier potassium channel activity	1/4017	25/18639	0.04	0.185601194921583	0.997694941109877	1
GO:0005200	structural constituent of cytoskeleton	13/4017	112/18639	0.116071428571429	0.538574895977809	0.997900559721454	1
GO:0015459	potassium channel regulator activity	5/4017	59/18639	0.0847457627118644	0.393222870596575	0.99796625951718	1
GO:0001664	G protein-coupled receptor binding	45/4017	297/18639	0.151515151515152	0.703034829248421	0.998008179308717	1
GO:0004866	endopeptidase inhibitor activity	21/4017	161/18639	0.130434782608696	0.605221287787772	0.998020803841078	1
GO:0008066	glutamate receptor activity	1/4017	26/18639	0.0384615384615385	0.178462687424599	0.998192385053232	1
GO:0019865	immunoglobulin binding	1/4017	26/18639	0.0384615384615385	0.178462687424599	0.998192385053232	1
GO:0008009	chemokine activity	3/4017	45/18639	0.0666666666666667	0.309335324869305	0.998425630740924	1
GO:0030414	peptidase inhibitor activity	22/4017	169/18639	0.130177514792899	0.604027557437105	0.998450638574621	1
GO:0015293	symporter activity	18/4017	146/18639	0.123287671232877	0.572058477498031	0.998622321791031	1
GO:0005254	chloride channel activity	8/4017	83/18639	0.0963855421686747	0.447231794991767	0.998758808710496	1
GO:0015294	solute:monoatomic cation symporter activity	13/4017	116/18639	0.112068965517241	0.520003347840643	0.998795000163525	1
GO:0005242	inward rectifier potassium channel activity	1/4017	28/18639	0.0357142857142857	0.165715352608556	0.998888436041864	1
GO:0038187	pattern recognition receptor activity	3/4017	48/18639	0.0625	0.290001867064974	0.999144328711587	1
GO:0071855	neuropeptide receptor binding	2/4017	40/18639	0.05	0.232001493651979	0.999278544921683	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/4017	30/18639	0.0333333333333333	0.154667662434653	0.999316501920372	1
GO:0008227	G protein-coupled amine receptor activity	2/4017	41/18639	0.0487804878048781	0.226342920636077	0.99942136359229	1
GO:0005184	neuropeptide hormone activity	1/4017	31/18639	0.032258064516129	0.149678383001277	0.999464044065886	1
GO:0160041	neuropeptide activity	1/4017	32/18639	0.03125	0.145000933532487	0.999579743495558	1
GO:0046943	carboxylic acid transmembrane transporter activity	23/4017	188/18639	0.122340425531915	0.567663229148459	0.999679248006461	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	3/4017	53/18639	0.0566037735849057	0.262643200360731	0.999694877529901	1
GO:0005342	organic acid transmembrane transporter activity	23/4017	189/18639	0.121693121693122	0.564659719999526	0.999716929571239	1
GO:0015103	inorganic anion transmembrane transporter activity	19/4017	165/18639	0.115151515151515	0.5343064702288	0.999740153560678	1
GO:0015020	glucuronosyltransferase activity	1/4017	34/18639	0.0294117647058824	0.136471466854105	0.999741615840187	1
GO:0022824	transmitter-gated monoatomic ion channel activity	4/4017	63/18639	0.0634920634920635	0.2946050713041	0.999778013612409	1
GO:0022835	transmitter-gated channel activity	4/4017	63/18639	0.0634920634920635	0.2946050713041	0.999778013612409	1
GO:0005343	organic acid:sodium symporter activity	1/4017	35/18639	0.0285714285714286	0.132572282086845	0.999797403487055	1
GO:0042379	chemokine receptor binding	5/4017	72/18639	0.0694444444444444	0.32222429673886	0.999815997385757	1
GO:0008509	monoatomic anion transmembrane transporter activity	16/4017	149/18639	0.10738255033557	0.498258241400224	0.999828977718738	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/4017	56/18639	0.0535714285714286	0.248573028912835	0.999836936702416	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/4017	36/18639	0.0277777777777778	0.128889718695544	0.999841148390973	1
GO:0030280	structural constituent of skin epidermis	1/4017	37/18639	0.027027027027027	0.125406212784854	0.999875449681811	1
GO:0000146	microfilament motor activity	1/4017	38/18639	0.0263157894736842	0.122106049290515	0.999902345640749	1
GO:0005244	voltage-gated monoatomic ion channel activity	19/4017	173/18639	0.109826589595376	0.509598656576601	0.99991249451056	1
GO:0003777	microtubule motor activity	4/4017	68/18639	0.0588235294117647	0.272942933708211	0.999918241702656	1
GO:0048020	CCR chemokine receptor binding	2/4017	50/18639	0.04	0.185601194921583	0.99992217942162	1
GO:0098960	postsynaptic neurotransmitter receptor activity	4/4017	69/18639	0.0579710144927536	0.268987239016787	0.999933172229292	1
GO:0022832	voltage-gated channel activity	19/4017	175/18639	0.108571428571429	0.503774671930012	0.999933760064283	1
GO:0005272	sodium channel activity	2/4017	51/18639	0.0392156862745098	0.181961955805474	0.99993785457855	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	71/4017	484/18639	0.146694214876033	0.680665539226881	0.999960661496659	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	4/4017	73/18639	0.0547945205479452	0.254248212221347	0.999970339959674	1
GO:0003730	mRNA 3'-UTR binding	32/4017	262/18639	0.122137404580153	0.56672120586743	0.999970680220237	1
GO:0008083	growth factor activity	16/4017	162/18639	0.0987654320987654	0.458274555361934	0.999974619738347	1
GO:0022843	voltage-gated monoatomic cation channel activity	13/4017	143/18639	0.0909090909090909	0.421820897549053	0.99997952713909	1
GO:0001216	DNA-binding transcription activator activity	71/4017	491/18639	0.144602851323829	0.670961549869267	0.999979581064168	1
GO:0046873	metal ion transmembrane transporter activity	63/4017	450/18639	0.14	0.649604182225542	0.99998632626227	1
GO:0008188	neuropeptide receptor activity	1/4017	48/18639	0.0208333333333333	0.096667289021658	0.999991433453826	1
GO:0140375	immune receptor activity	14/4017	156/18639	0.0897435897435897	0.416412937324065	0.999992247693613	1
GO:0030594	neurotransmitter receptor activity	6/4017	97/18639	0.0618556701030928	0.287012157095232	0.999992909831657	1
GO:0015108	chloride transmembrane transporter activity	9/4017	121/18639	0.0743801652892562	0.345126188903771	0.999993553957909	1
GO:0005261	monoatomic cation channel activity	42/4017	341/18639	0.12316715542522	0.57149928055033	0.999996912318858	1
GO:0001653	peptide receptor activity	9/4017	128/18639	0.0703125	0.326252100448096	0.999998176563407	1
GO:0008528	G protein-coupled peptide receptor activity	8/4017	122/18639	0.0655737704918033	0.304264253969809	0.999998697644372	1
GO:0015079	potassium ion transmembrane transporter activity	13/4017	160/18639	0.08125	0.377002427184466	0.999998755372553	1
GO:0015370	solute:sodium symporter activity	3/4017	79/18639	0.0379746835443038	0.176203666064794	0.999998842265644	1
GO:0005267	potassium channel activity	7/4017	124/18639	0.0564516129032258	0.261937170252234	0.999999815274621	1
GO:0005249	voltage-gated potassium channel activity	4/4017	98/18639	0.0408163265306122	0.189388974409779	0.999999843078044	1
GO:0005216	monoatomic ion channel activity	55/4017	448/18639	0.122767857142857	0.569646524591913	0.999999901154369	1
GO:0015081	sodium ion transmembrane transporter activity	11/4017	164/18639	0.0670731707317073	0.311221515874606	0.999999956801711	1
GO:0099094	ligand-gated monoatomic cation channel activity	6/4017	136/18639	0.0441176470588235	0.204707200281158	0.999999997273493	1
GO:0005125	cytokine activity	18/4017	234/18639	0.0769230769230769	0.356925374849199	0.999999997892536	1
GO:0022836	gated channel activity	29/4017	318/18639	0.0911949685534591	0.423147378358956	0.999999999231224	1
GO:0015276	ligand-gated monoatomic ion channel activity	11/4017	186/18639	0.0591397849462366	0.274410368835674	0.999999999301342	1
GO:0022834	ligand-gated channel activity	11/4017	188/18639	0.0585106382978723	0.271491109592742	0.999999999523516	1
GO:0003823	antigen binding	9/4017	174/18639	0.0517241379310345	0.24000154515722	0.999999999726321	1
GO:0005179	hormone activity	3/4017	132/18639	0.0227272727272727	0.105455224387263	0.99999999999249	1
GO:0030371	translation repressor activity	7/4017	329/18639	0.0212765957446809	0.098724039851906	1	1
GO:0045182	translation regulator activity	11/4017	356/18639	0.0308988764044944	0.143371709560212	1	1