ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	211/4140	495/18639	0.426262626262626	1.919108476065	7.38589647891005e-25	9.50564876835724e-22
GO:0019787	ubiquitin-like protein transferase activity	186/4140	479/18639	0.388308977035491	1.74823454660978	7.04737265474044e-17	4.53498430332547e-14
GO:0042393	histone binding	112/4140	247/18639	0.453441295546559	2.04147157190635	4.39215228286214e-16	1.88423332934786e-13
GO:0016755	aminoacyltransferase activity	188/4140	496/18639	0.379032258064516	1.70646914446003	8.25409229796706e-16	2.6557541968709e-13
GO:0004842	ubiquitin-protein transferase activity	169/4140	449/18639	0.376391982182628	1.69458216326135	4.99384232291165e-14	1.28541501391746e-11
GO:0016887	ATP hydrolysis activity	157/4140	417/18639	0.376498800959233	1.69506307997081	3.87739267932591e-13	8.31700729715409e-11
GO:0008094	ATP-dependent activity, acting on DNA	93/4140	210/18639	0.442857142857143	1.9938198757764	7.47447231849078e-13	1.37423512484252e-10
GO:0044389	ubiquitin-like protein ligase binding	127/4140	322/18639	0.394409937888199	1.77570213340535	1.67628295606166e-12	2.6967202055642e-10
GO:0140098	catalytic activity, acting on RNA	145/4140	387/18639	0.374677002583979	1.68686102685092	4.7130925720919e-12	6.73972237809142e-10
GO:0061775	cohesin loader activity	72/4140	153/18639	0.470588235294118	2.11867007672634	8.62064837950549e-12	1.09249118815601e-09
GO:0000510	H3-H4 histone complex chaperone activity	71/4140	151/18639	0.470198675496689	2.11691621076879	1.26015807554416e-11	1.09249118815601e-09
GO:0140584	chromatin extrusion motor activity	71/4140	151/18639	0.470198675496689	2.11691621076879	1.26015807554416e-11	1.09249118815601e-09
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	71/4140	151/18639	0.470198675496689	2.11691621076879	1.26015807554416e-11	1.09249118815601e-09
GO:0140849	ATP-dependent H2AZ histone chaperone activity	71/4140	151/18639	0.470198675496689	2.11691621076879	1.26015807554416e-11	1.09249118815601e-09
GO:0003689	DNA clamp loader activity	74/4140	160/18639	0.4625	2.08225543478261	1.27329975309559e-11	1.09249118815601e-09
GO:0015616	DNA translocase activity	71/4140	152/18639	0.467105263157895	2.10298913043478	1.85464317384898e-11	1.25965039845741e-09
GO:0140674	ATP-dependent histone chaperone activity	71/4140	152/18639	0.467105263157895	2.10298913043478	1.85464317384898e-11	1.25965039845741e-09
GO:0140658	ATP-dependent chromatin remodeler activity	73/4140	158/18639	0.462025316455696	2.08011832691249	1.85723694134028e-11	1.25965039845741e-09
GO:0004386	helicase activity	72/4140	155/18639	0.464516129032258	2.09133239831697	1.85962374286642e-11	1.25965039845741e-09
GO:0031625	ubiquitin protein ligase binding	118/4140	302/18639	0.390728476821192	1.75912755542758	2.09731732457042e-11	1.34962369836106e-09
GO:0140097	catalytic activity, acting on DNA	128/4140	336/18639	0.380952380952381	1.71511387163561	2.29789223213687e-11	1.40827966798102e-09
GO:0061659	ubiquitin-like protein ligase activity	138/4140	372/18639	0.370967741935484	1.67016129032258	3.49936807053056e-11	2.04713032126038e-09
GO:0140297	DNA-binding transcription factor binding	171/4140	488/18639	0.350409836065574	1.57760602280827	3.80176579127714e-11	2.12733590146682e-09
GO:0140030	modification-dependent protein binding	77/4140	173/18639	0.445086705202312	2.00385775320432	5.10404967580066e-11	2.7370466386481e-09
GO:0140713	histone chaperone activity	74/4140	164/18639	0.451219512195122	2.03146871686108	5.47619610429206e-11	2.81914575448955e-09
GO:0043021	ribonucleoprotein complex binding	78/4140	177/18639	0.440677966101695	1.98400884303611	6.95256504480893e-11	3.44151969718042e-09
GO:0003713	transcription coactivator activity	102/4140	256/18639	0.3984375	1.79383491847826	1.29172448005114e-10	6.15722002157712e-09
GO:0140104	molecular carrier activity	99/4140	249/18639	0.397590361445783	1.79002095337873	2.76526600745589e-10	1.27103476842705e-08
GO:0003714	transcription corepressor activity	85/4140	204/18639	0.416666666666667	1.87590579710145	3.25289836055653e-10	1.44361385863319e-08
GO:0031072	heat shock protein binding	61/4140	131/18639	0.465648854961832	2.09643212744773	5.5859325402278e-10	2.39636505975773e-08
GO:0070063	RNA polymerase binding	35/4140	59/18639	0.593220338983051	2.6707811348563	8.05013570397326e-10	3.34210472613342e-08
GO:0140597	protein carrier chaperone	79/4140	188/18639	0.420212765957447	1.89187095282146	8.41718648642916e-10	3.38528719001073e-08
GO:0003725	double-stranded RNA binding	40/4140	75/18639	0.533333333333333	2.40115942028985	3.95222946639953e-09	1.46661018084985e-07
GO:0044183	protein folding chaperone	40/4140	75/18639	0.533333333333333	2.40115942028985	3.95222946639953e-09	1.46661018084985e-07
GO:0061630	ubiquitin protein ligase activity	126/4140	353/18639	0.356940509915014	1.60700825224781	3.98845037527155e-09	1.46661018084985e-07
GO:0043175	RNA polymerase core enzyme binding	27/4140	42/18639	0.642857142857143	2.89425465838509	5.83315734847892e-09	2.08535375208121e-07
GO:0016779	nucleotidyltransferase activity	60/4140	136/18639	0.441176470588235	1.98625319693095	9.98844105876348e-09	3.47435774125097e-07
GO:0000993	RNA polymerase II complex binding	24/4140	36/18639	0.666666666666667	3.00144927536232	1.42067664239114e-08	4.80705895846452e-07
GO:0060589	nucleoside-triphosphatase regulator activity	162/4140	490/18639	0.330612244897959	1.48847382431233	1.45668453286804e-08	4.80705895846452e-07
GO:0030695	GTPase regulator activity	161/4140	489/18639	0.329243353783231	1.48231083844581	2.21420321846219e-08	7.1241988554021e-07
GO:0008186	ATP-dependent activity, acting on RNA	40/4140	79/18639	0.506329113924051	2.27958172812328	2.75785756915207e-08	8.54141644302143e-07
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	122/4140	349/18639	0.349570200573066	1.57382583779743	2.78740862942424e-08	8.54141644302143e-07
GO:0046966	nuclear thyroid hormone receptor binding	20/4140	28/18639	0.714285714285714	3.21583850931677	3.87402780872299e-08	1.15950553251779e-06
GO:0003724	RNA helicase activity	39/4140	77/18639	0.506493506493506	2.28032185206098	4.05395937828535e-08	1.18578311814847e-06
GO:0032182	ubiquitin-like protein binding	53/4140	120/18639	0.441666666666667	1.98846014492754	6.78816532998401e-08	1.94141528437543e-06
GO:0140463	chromatin-protein adaptor activity	30/4140	54/18639	0.555555555555556	2.5012077294686	1.02587109746403e-07	2.87020891833958e-06
GO:0001098	basal transcription machinery binding	32/4140	60/18639	0.533333333333333	2.40115942028985	1.4022246667482e-07	3.7597148877186e-06
GO:0001099	basal RNA polymerase II transcription machinery binding	32/4140	60/18639	0.533333333333333	2.40115942028985	1.4022246667482e-07	3.7597148877186e-06
GO:0051082	unfolded protein binding	52/4140	121/18639	0.429752066115702	1.93481854114265	2.61938575565265e-07	6.87989687249993e-06
GO:0004532	RNA exonuclease activity	24/4140	40/18639	0.6	2.70130434782609	2.76444655974449e-07	7.11568544478233e-06
GO:0140034	methylation-dependent protein binding	37/4140	76/18639	0.486842105263158	2.19184782608696	3.28400001214318e-07	8.28727061887897e-06
GO:0035064	methylated histone binding	36/4140	74/18639	0.486486486486487	2.19024676850764	4.8285739557854e-07	1.19507205405689e-05
GO:0003697	single-stranded DNA binding	51/4140	121/18639	0.421487603305785	1.89761049227452	6.99914015034542e-07	1.69960252330086e-05
GO:0051087	protein-folding chaperone binding	55/4140	134/18639	0.41044776119403	1.84790720311486	7.30630597681835e-07	1.74133625780837e-05
GO:0031267	small GTPase binding	98/4140	283/18639	0.346289752650177	1.5590566907359	1.01793989442842e-06	2.38197935296251e-05
GO:0106310	protein serine kinase activity	119/4140	361/18639	0.329639889196676	1.48409610983982	1.3774556090823e-06	3.16568815873022e-05
GO:0140662	ATP-dependent protein folding chaperone	23/4140	40/18639	0.575	2.58875	1.40482610931212e-06	3.1719494783942e-05
GO:0003727	single-stranded RNA binding	40/4140	89/18639	0.449438202247191	2.02344894968246	1.54590748101783e-06	3.37842168595802e-05
GO:0140566	histone reader activity	21/4140	35/18639	0.6	2.70130434782609	1.54877140226514e-06	3.37842168595802e-05
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	64/4140	167/18639	0.383233532934132	1.72538401457954	1.69383669287109e-06	3.60102635604302e-05
GO:0004674	protein serine/threonine kinase activity	138/4140	433/18639	0.318706697459584	1.43487297921478	1.70678016875388e-06	3.60102635604302e-05
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	22/4140	38/18639	0.578947368421053	2.60652173913043	2.0334296820662e-06	4.22100645293419e-05
GO:0051020	GTPase binding	105/4140	315/18639	0.333333333333333	1.50072463768116	3.20132762613245e-06	6.53985500767058e-05
GO:0008135	translation factor activity, RNA binding	37/4140	83/18639	0.44578313253012	2.00699319015191	4.76798331612193e-06	9.58811644976394e-05
GO:0015631	tubulin binding	123/4140	385/18639	0.319480519480519	1.43835686053077	5.36673415033721e-06	0.000106261336176677
GO:0005096	GTPase activator activity	92/4140	271/18639	0.339483394833948	1.52841328413284	5.49675150177636e-06	0.000107186654284639
GO:0043022	ribosome binding	46/4140	112/18639	0.410714285714286	1.84910714285714	5.60061601050162e-06	0.000107581982171874
GO:0003743	translation initiation factor activity	26/4140	51/18639	0.509803921568627	2.29522591645354	6.2189544403182e-06	0.000116905988594942
GO:0019902	phosphatase binding	69/4140	190/18639	0.363157894736842	1.635	6.26768703422765e-06	0.000116905988594942
GO:0004527	exonuclease activity	37/4140	84/18639	0.44047619047619	1.98310041407867	6.70960671555525e-06	0.000121623434407318
GO:0180051	translation factor activity	37/4140	84/18639	0.44047619047619	1.98310041407867	6.70960671555525e-06	0.000121623434407318
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	29/4140	60/18639	0.483333333333333	2.17605072463768	7.22762217537787e-06	0.000127532472874103
GO:0043130	ubiquitin binding	42/4140	100/18639	0.42	1.89091304347826	7.23377662766865e-06	0.000127532472874103
GO:0000175	3'-5'-RNA exonuclease activity	20/4140	35/18639	0.571428571428571	2.57267080745342	7.82441153818988e-06	0.00013608131958987
GO:0001222	transcription corepressor binding	25/4140	49/18639	0.510204081632653	2.29702750665484	9.18507566399198e-06	0.000157615898394102
GO:0019783	ubiquitin-like protein peptidase activity	50/4140	127/18639	0.393700787401575	1.77250941458405	9.31129257002957e-06	0.000157679388653001
GO:0042162	telomeric DNA binding	21/4140	38/18639	0.552631578947368	2.48804347826087	9.49882758605163e-06	0.000158766118224006
GO:0140857	histone H3T45 kinase activity	84/4140	246/18639	0.341463414634146	1.5373276776246	1.07352297680206e-05	0.00017713129117234
GO:0061650	ubiquitin-like protein conjugating enzyme activity	22/4140	41/18639	0.536585365853659	2.41580063626723	1.10465709917041e-05	0.00017996122615599
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	83/4140	243/18639	0.34156378600823	1.53777956700662	1.19261549607444e-05	0.000191862017930976
GO:0035403	histone H3T6 kinase activity	84/4140	247/18639	0.340080971659919	1.53110367892977	1.27668886913584e-05	0.000202851675873806
GO:0004679	AMP-activated protein kinase activity	84/4140	248/18639	0.338709677419355	1.52492987377279	1.51519686287739e-05	0.000216709371839604
GO:0140296	general transcription initiation factor binding	26/4140	53/18639	0.490566037735849	2.20861361771944	1.52160470930375e-05	0.000216709371839604
GO:0004676	3-phosphoinositide-dependent protein kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0004711	ribosomal protein S6 kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0035175	histone H3S10 kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0035979	histone H2AXS139 kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0044022	histone H3S28 kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0044023	histone H4S1 kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0044024	histone H2AS1 kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0044025	histone H2BS14 kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0072354	histone H3T3 kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0072371	histone H2AS121 kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0072518	Rho-dependent protein serine/threonine kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0140823	histone H2BS36 kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0140855	histone H3S57 kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0140995	histone H2A kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0140997	histone H4 kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0140998	histone H2B kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:1990244	histone H2AT120 kinase activity	83/4140	245/18639	0.338775510204082	1.52522626441881	1.68383350302723e-05	0.000216709371839604
GO:0004677	DNA-dependent protein kinase activity	83/4140	246/18639	0.33739837398374	1.51902615765288	1.99460512067563e-05	0.000254164038644509
GO:0016922	nuclear receptor binding	52/4140	137/18639	0.37956204379562	1.70885433195811	2.08710196325365e-05	0.000263343159481122
GO:0019207	kinase regulator activity	94/4140	287/18639	0.327526132404181	1.47457960915013	2.25074983571101e-05	0.000281234469763113
GO:0035402	histone H3T11 kinase activity	83/4140	247/18639	0.336032388663968	1.5128762541806	2.35794078456469e-05	0.00029179517208988
GO:0140517	protein-RNA adaptor activity	14/4140	22/18639	0.636363636363636	2.86501976284585	3.53562814286453e-05	0.000429754824009581
GO:0010485	histone H4 acetyltransferase activity	19/4140	35/18639	0.542857142857143	2.44403726708075	3.53955022105793e-05	0.000429754824009581
GO:0031491	nucleosome binding	32/4140	74/18639	0.432432432432432	1.94688601645123	4.30564515124803e-05	0.000517884608379085
GO:1990841	promoter-specific chromatin binding	30/4140	68/18639	0.441176470588235	1.98625319693095	4.68171858305699e-05	0.000553391372160199
GO:0008168	methyltransferase activity	70/4140	204/18639	0.343137254901961	1.54486359761296	4.68684223507861e-05	0.000553391372160199
GO:0042826	histone deacetylase binding	48/4140	127/18639	0.377952755905512	1.70160903800068	4.82756775998197e-05	0.00056482542791789
GO:0017025	TBP-class protein binding	15/4140	25/18639	0.6	2.70130434782609	5.00115841171648e-05	0.000579864042871992
GO:0045309	protein phosphorylated amino acid binding	27/4140	59/18639	0.457627118644068	2.06031687546057	5.06637807836865e-05	0.000582181123826826
GO:0005484	SNAP receptor activity	19/4140	36/18639	0.527777777777778	2.37614734299517	5.93844293798034e-05	0.0006763518638213
GO:0004402	histone acetyltransferase activity	21/4140	42/18639	0.5	2.25108695652174	6.96363703627744e-05	0.00078018491313016
GO:0001221	transcription coregulator binding	44/4140	115/18639	0.382608695652174	1.72257088846881	6.98496690809325e-05	0.00078018491313016
GO:0008276	protein methyltransferase activity	38/4140	95/18639	0.4	1.80086956521739	7.03196969099445e-05	0.00078018491313016
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	14/4140	23/18639	0.608695652173913	2.74045368620038	7.18579581822364e-05	0.000783738916784222
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	14/4140	23/18639	0.608695652173913	2.74045368620038	7.18579581822364e-05	0.000783738916784222
GO:0030544	Hsp70 protein binding	24/4140	51/18639	0.470588235294118	2.11867007672634	7.54130413645424e-05	0.000815601548203076
GO:0019887	protein kinase regulator activity	83/4140	255/18639	0.325490196078431	1.46541346973572	8.38063991482279e-05	0.000898823630864745
GO:0008234	cysteine-type peptidase activity	64/4140	187/18639	0.342245989304813	1.54085096489189	0.000105419008366882	0.00112127490717501
GO:0008408	3'-5' exonuclease activity	26/4140	58/18639	0.448275862068966	2.01821589205397	0.00010645032132343	0.00112296363560045
GO:0010484	histone H3 acetyltransferase activity	16/4140	29/18639	0.551724137931034	2.48395802098951	0.000113774664628959	0.00119047149087374
GO:0004540	RNA nuclease activity	45/4140	121/18639	0.371900826446281	1.67436219906576	0.000127370823158584	0.00132198588229917
GO:0031490	chromatin DNA binding	47/4140	128/18639	0.3671875	1.65314198369565	0.00013032844623222	0.00133267939146875
GO:0051059	NF-kappaB binding	17/4140	32/18639	0.53125	2.39177989130435	0.000130472108255681	0.00133267939146875
GO:0140033	acetylation-dependent protein binding	14/4140	24/18639	0.583333333333333	2.62626811594203	0.00013720450852425	0.00139041104307645
GO:0045296	cadherin binding	103/4140	334/18639	0.308383233532934	1.38839494923197	0.000141451273151043	0.00142224834801088
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	9/4140	12/18639	0.75	3.37663043478261	0.000147731139370546	0.00144037860886282
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	9/4140	12/18639	0.75	3.37663043478261	0.000147731139370546	0.00144037860886282
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	9/4140	12/18639	0.75	3.37663043478261	0.000147731139370546	0.00144037860886282
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	9/4140	12/18639	0.75	3.37663043478261	0.000147731139370546	0.00144037860886282
GO:0061733	protein-lysine-acetyltransferase activity	22/4140	47/18639	0.468085106382979	2.10740055504163	0.000164168696401198	0.00157675456916673
GO:0140938	histone H3 methyltransferase activity	22/4140	47/18639	0.468085106382979	2.10740055504163	0.000164168696401198	0.00157675456916673
GO:0045322	unmethylated CpG binding	8/4140	10/18639	0.8	3.60173913043478	0.000171061081137561	0.00163078230684474
GO:0005525	GTP binding	114/4140	378/18639	0.301587301587302	1.35779848171153	0.00017581327704264	0.00166376240848439
GO:0002039	p53 binding	29/4140	69/18639	0.420289855072464	1.89221802142407	0.000177858259117235	0.00167082904732761
GO:0043995	histone H4K5 acetyltransferase activity	16/4140	30/18639	0.533333333333333	2.40115942028985	0.000193666271725934	0.00178034636936626
GO:0043996	histone H4K8 acetyltransferase activity	16/4140	30/18639	0.533333333333333	2.40115942028985	0.000193666271725934	0.00178034636936626
GO:0043997	histone H4K12 acetyltransferase activity	16/4140	30/18639	0.533333333333333	2.40115942028985	0.000193666271725934	0.00178034636936626
GO:0004407	histone deacetylase activity	13/4140	22/18639	0.590909090909091	2.66037549407115	0.000200016256258207	0.00181282339298811
GO:0033558	protein lysine deacetylase activity	13/4140	22/18639	0.590909090909091	2.66037549407115	0.000200016256258207	0.00181282339298811
GO:0051219	phosphoprotein binding	36/4140	93/18639	0.387096774193548	1.74277699859748	0.000234290051018645	0.00210861045916781
GO:0042054	histone methyltransferase activity	28/4140	67/18639	0.417910447761194	1.88150551589877	0.000256188483160498	0.00228968456824695
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	46/4140	128/18639	0.359375	1.61796875	0.000270735263703047	0.00240300885783325
GO:0042809	nuclear vitamin D receptor binding	10/4140	15/18639	0.666666666666667	3.00144927536232	0.000283952976057173	0.00250248814389957
GO:0016741	transferase activity, transferring one-carbon groups	70/4140	215/18639	0.325581395348837	1.46582406471183	0.00028583615315315	0.00250248814389957
GO:0036408	histone H3K14 acetyltransferase activity	15/4140	28/18639	0.535714285714286	2.41187888198758	0.00028777641437229	0.00250248814389957
GO:0003678	DNA helicase activity	30/4140	74/18639	0.405405405405405	1.82520564042303	0.000297176099090698	0.0025668834867767
GO:0035173	histone kinase activity	108/4140	360/18639	0.3	1.35065217391304	0.000318692198989058	0.00273437906732612
GO:0101005	deubiquitinase activity	42/4140	115/18639	0.365217391304348	1.64427221172023	0.00033029905385069	0.00281519789606515
GO:0030145	manganese ion binding	28/4140	68/18639	0.411764705882353	1.85383631713555	0.000344117382655794	0.00289006042935061
GO:0016763	pentosyltransferase activity	22/4140	49/18639	0.448979591836735	2.02138420585626	0.000344807454912883	0.00289006042935061
GO:0008170	N-methyltransferase activity	37/4140	98/18639	0.377551020408163	1.69980035492458	0.000345819196674432	0.00289006042935061
GO:0140996	histone H3 kinase activity	107/4140	357/18639	0.299719887955182	1.34939106077213	0.000351791350862584	0.00291727094318826
GO:0004518	nuclease activity	68/4140	209/18639	0.325358851674641	1.46482213438735	0.000353608599174334	0.00291727094318826
GO:0070577	lysine-acetylated histone binding	13/4140	23/18639	0.565217391304348	2.54470699432892	0.00036662204375697	0.00300536668990586
GO:0004535	poly(A)-specific ribonuclease activity	9/4140	13/18639	0.692307692307692	3.11688963210702	0.000385046360831697	0.00311669601503393
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	9/4140	13/18639	0.692307692307692	3.11688963210702	0.000385046360831697	0.00311669601503393
GO:0141003	histone H2AX kinase activity	106/4140	354/18639	0.299435028248588	1.34810857283223	0.000388290828054534	0.00312331434816366
GO:0034212	protein N-acetyltransferase activity	23/4140	53/18639	0.433962264150943	1.95377358490566	0.000466274093407845	0.00372729663488135
GO:0106222	lncRNA binding	15/4140	29/18639	0.517241379310345	2.32871064467766	0.000474206860525859	0.00376731005862211
GO:0005085	guanyl-nucleotide exchange factor activity	73/4140	230/18639	0.317391304347826	1.42895085066163	0.000498691379579039	0.00393752027925291
GO:0061631	ubiquitin conjugating enzyme activity	17/4140	35/18639	0.485714285714286	2.1867701863354	0.000523964054034062	0.00411183986305998
GO:0017069	snRNA binding	23/4140	54/18639	0.425925925925926	1.91759259259259	0.000643142633756372	0.0050165125432997
GO:0008173	RNA methyltransferase activity	27/4140	67/18639	0.402985074626866	1.81430889033095	0.000653226052192005	0.00506446945283802
GO:0035591	signaling adaptor activity	45/4140	129/18639	0.348837209302326	1.57052578361982	0.000658993963314514	0.00507859419632204
GO:0140693	molecular condensate scaffold activity	21/4140	48/18639	0.4375	1.96970108695652	0.00071325559100982	0.00546404729541451
GO:0019903	protein phosphatase binding	49/4140	144/18639	0.340277777777778	1.53198973429952	0.00074088282534903	0.00564210766996569
GO:0035925	mRNA 3'-UTR AU-rich region binding	15/4140	30/18639	0.5	2.25108695652174	0.000754747449325782	0.00571388216048401
GO:0004197	cysteine-type endopeptidase activity	33/4140	88/18639	0.375	1.6883152173913	0.000808701043662634	0.00608653943388193
GO:0140223	general transcription initiation factor activity	27/4140	68/18639	0.397058823529412	1.78762787723785	0.000856785419935363	0.00641094671777217
GO:0008017	microtubule binding	84/4140	276/18639	0.304347826086957	1.37022684310019	0.000863718169779684	0.00642546407229164
GO:0004721	phosphoprotein phosphatase activity	57/4140	175/18639	0.325714285714286	1.46642236024845	0.000983606345004405	0.00727529520701534
GO:0016407	acetyltransferase activity	35/4140	96/18639	0.364583333333333	1.64141757246377	0.00103153945622094	0.00758623588660773
GO:0017056	structural constituent of nuclear pore	13/4140	25/18639	0.52	2.34113043478261	0.00105979093956624	0.00774972124557812
GO:0140767	enzyme-substrate adaptor activity	47/4140	139/18639	0.338129496402878	1.52231779793556	0.00109345469556663	0.00795071295589976
GO:0008080	N-acetyltransferase activity	27/4140	69/18639	0.391304347826087	1.7617202268431	0.00111336591928109	0.00800503876041768
GO:0016279	protein-lysine N-methyltransferase activity	27/4140	69/18639	0.391304347826087	1.7617202268431	0.00111336591928109	0.00800503876041768
GO:0051019	mitogen-activated protein kinase binding	14/4140	28/18639	0.5	2.25108695652174	0.00112870153152306	0.00804428754900995
GO:0030331	nuclear estrogen receptor binding	18/4140	40/18639	0.45	2.02597826086957	0.00113132559935571	0.00804428754900995
GO:0004659	prenyltransferase activity	10/4140	17/18639	0.588235294117647	2.64833759590793	0.00117964110514797	0.0082934892531691
GO:0070403	NAD+ binding	10/4140	17/18639	0.588235294117647	2.64833759590793	0.00117964110514797	0.0082934892531691
GO:0019001	guanyl nucleotide binding	115/4140	400/18639	0.2875	1.294375	0.0011921488048456	0.0082934892531691
GO:0032561	guanyl ribonucleotide binding	115/4140	400/18639	0.2875	1.294375	0.0011921488048456	0.0082934892531691
GO:0043047	single-stranded telomeric DNA binding	8/4140	12/18639	0.666666666666667	3.00144927536232	0.00121754494144143	0.00833500180656979
GO:1990247	N6-methyladenosine-containing RNA reader activity	8/4140	12/18639	0.666666666666667	3.00144927536232	0.00121754494144143	0.00833500180656979
GO:1990817	poly(A) RNA polymerase activity	8/4140	12/18639	0.666666666666667	3.00144927536232	0.00121754494144143	0.00833500180656979
GO:0017124	SH3 domain binding	40/4140	115/18639	0.347826086956522	1.56597353497164	0.00135635944718088	0.00923616194985072
GO:0000287	magnesium ion binding	71/4140	230/18639	0.308695652173913	1.38980151228733	0.00137162585144638	0.00929096037269209
GO:0000339	RNA cap binding	11/4140	20/18639	0.55	2.47619565217391	0.00142156278157578	0.00952891302025013
GO:0140939	histone H4 methyltransferase activity	11/4140	20/18639	0.55	2.47619565217391	0.00142156278157578	0.00952891302025013
GO:0016278	lysine N-methyltransferase activity	27/4140	70/18639	0.385714285714286	1.73655279503106	0.00143389730305066	0.00956179186023939
GO:0044013	histone H2B acetyltransferase activity	12/4140	23/18639	0.521739130434783	2.34896030245747	0.0015893334352871	0.0105436707794562
GO:0003684	damaged DNA binding	28/4140	74/18639	0.378378378378378	1.70352526439483	0.00166211462893576	0.0109313761495599
GO:0098505	G-rich strand telomeric DNA binding	7/4140	10/18639	0.7	3.15152173913043	0.00167325648909347	0.0109313761495599
GO:0099122	RNA polymerase II C-terminal domain binding	7/4140	10/18639	0.7	3.15152173913043	0.00167325648909347	0.0109313761495599
GO:0061578	K63-linked deubiquitinase activity	9/4140	15/18639	0.6	2.70130434782609	0.00173711846193937	0.0112870464830861
GO:0140142	nucleocytoplasmic carrier activity	15/4140	32/18639	0.46875	2.11039402173913	0.00174523873359295	0.0112870464830861
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	20/4140	48/18639	0.416666666666667	1.87590579710145	0.00196018871567816	0.012613814385389
GO:0061980	regulatory RNA binding	23/4140	58/18639	0.396551724137931	1.78534482758621	0.00205347642164606	0.0131483788788979
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	30/4140	82/18639	0.365853658536585	1.64713679745493	0.00213968340135653	0.0136325373145834
GO:0003924	GTPase activity	96/4140	331/18639	0.290030211480363	1.30576645212137	0.00215697641510628	0.0136750179617822
GO:0051879	Hsp90 protein binding	18/4140	42/18639	0.428571428571429	1.92950310559006	0.00222856778019049	0.0140596408485547
GO:0051010	microtubule plus-end binding	11/4140	21/18639	0.523809523809524	2.35828157349897	0.00238957355900548	0.0150018593680003
GO:0044390	ubiquitin-like protein conjugating enzyme binding	16/4140	36/18639	0.444444444444444	2.00096618357488	0.00246273992241085	0.0153861469909843
GO:0043998	histone H2A acetyltransferase activity	12/4140	24/18639	0.5	2.25108695652174	0.00254091501245128	0.0156998153915151
GO:0046975	histone H3K36 methyltransferase activity	8/4140	13/18639	0.615384615384615	2.77056856187291	0.00254954267041699	0.0156998153915151
GO:0140852	histone ubiquitin ligase activity	8/4140	13/18639	0.615384615384615	2.77056856187291	0.00254954267041699	0.0156998153915151
GO:0031624	ubiquitin conjugating enzyme binding	14/4140	30/18639	0.466666666666667	2.10101449275362	0.00260127702769078	0.0157610544692126
GO:0070566	adenylyltransferase activity	14/4140	30/18639	0.466666666666667	2.10101449275362	0.00260127702769078	0.0157610544692126
GO:0001671	ATPase activator activity	13/4140	27/18639	0.481481481481481	2.16771336553945	0.00260444666381394	0.0157610544692126
GO:0051536	iron-sulfur cluster binding	28/4140	76/18639	0.368421052631579	1.65869565217391	0.00262892175430372	0.0157610544692126
GO:0060590	ATPase regulator activity	20/4140	49/18639	0.408163265306122	1.83762200532387	0.00262956597264067	0.0157610544692126
GO:0019210	kinase inhibitor activity	32/4140	90/18639	0.355555555555556	1.6007729468599	0.00263296558731989	0.0157610544692126
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	30/4140	83/18639	0.36144578313253	1.62729177579885	0.00264990075386541	0.0157889919917814
GO:0036002	pre-mRNA binding	23/4140	59/18639	0.389830508474576	1.75508474576271	0.00266801294927256	0.0158236528373907
GO:0004843	cysteine-type deubiquitinase activity	37/4140	108/18639	0.342592592592593	1.5424114331723	0.00271323443047309	0.0160180399633893
GO:0043539	protein serine/threonine kinase activator activity	27/4140	73/18639	0.36986301369863	1.66518761167362	0.0029126445258622	0.0171167739944505
GO:0005521	lamin binding	9/4140	16/18639	0.5625	2.53247282608696	0.00319105306615219	0.0185831913852392
GO:0043023	ribosomal large subunit binding	9/4140	16/18639	0.5625	2.53247282608696	0.00319105306615219	0.0185831913852392
GO:0061791	GTPase motor activity	17/4140	40/18639	0.425	1.91342391304348	0.00325592974989069	0.018702073073309
GO:1990606	membrane scission GTPase motor activity	17/4140	40/18639	0.425	1.91342391304348	0.00325592974989069	0.018702073073309
GO:0004860	protein kinase inhibitor activity	30/4140	84/18639	0.357142857142857	1.60791925465839	0.0032604248426802	0.018702073073309
GO:0051540	metal cluster binding	28/4140	77/18639	0.363636363636364	1.63715415019763	0.00326959319463443	0.018702073073309
GO:0033192	calmodulin-dependent protein phosphatase activity	29/4140	81/18639	0.358024691358025	1.61188942565754	0.00362828175068968	0.0194715981359512
GO:0140791	histone H2AXS140 phosphatase activity	29/4140	81/18639	0.358024691358025	1.61188942565754	0.00362828175068968	0.0194715981359512
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	29/4140	81/18639	0.358024691358025	1.61188942565754	0.00362828175068968	0.0194715981359512
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	29/4140	81/18639	0.358024691358025	1.61188942565754	0.00362828175068968	0.0194715981359512
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	29/4140	81/18639	0.358024691358025	1.61188942565754	0.00362828175068968	0.0194715981359512
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	29/4140	81/18639	0.358024691358025	1.61188942565754	0.00362828175068968	0.0194715981359512
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	29/4140	81/18639	0.358024691358025	1.61188942565754	0.00362828175068968	0.0194715981359512
GO:1990439	MAP kinase serine/threonine phosphatase activity	29/4140	81/18639	0.358024691358025	1.61188942565754	0.00362828175068968	0.0194715981359512
GO:0019208	phosphatase regulator activity	39/4140	117/18639	0.333333333333333	1.50072463768116	0.00366947796204112	0.0194715981359512
GO:0032404	mismatch repair complex binding	7/4140	11/18639	0.636363636363636	2.86501976284585	0.00371886779990057	0.0194715981359512
GO:0070990	snRNP binding	7/4140	11/18639	0.636363636363636	2.86501976284585	0.00371886779990057	0.0194715981359512
GO:0001784	phosphotyrosine residue binding	19/4140	47/18639	0.404255319148936	1.82002775208141	0.00378462142285639	0.0194715981359512
GO:1990518	single-stranded 3'-5' DNA helicase activity	19/4140	47/18639	0.404255319148936	1.82002775208141	0.00378462142285639	0.0194715981359512
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0032931	histone H3K56 acetyltransferase activity	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0043992	histone H3K9 acetyltransferase activity	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0043993	histone H3K18 acetyltransferase activity	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0043994	histone H3K23 acetyltransferase activity	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0043999	histone H2AK5 acetyltransferase activity	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0044012	histone H2AK9 acetyltransferase activity	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0044014	histone H2BK5 acetyltransferase activity	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0044015	histone H2BK12 acetyltransferase activity	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0044016	histone H3K4 acetyltransferase activity	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0044017	histone H3K27 acetyltransferase activity	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0044018	histone H3K36 acetyltransferase activity	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0046972	histone H4K16 acetyltransferase activity	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0070034	telomerase RNA binding	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0140908	histone H3K122 acetyltransferase activity	11/4140	22/18639	0.5	2.25108695652174	0.00382775006091349	0.0194715981359512
GO:0019789	SUMO transferase activity	13/4140	28/18639	0.464285714285714	2.0902950310559	0.00388342577846605	0.0196770432160859
GO:0140789	histone phosphatase activity	44/4140	136/18639	0.323529411764706	1.45658567774936	0.00400956189877125	0.0202364947596808
GO:0004722	protein serine/threonine phosphatase activity	35/4140	103/18639	0.339805825242718	1.52986492190798	0.00404036824412054	0.0203123200397779
GO:0043014	alpha-tubulin binding	18/4140	44/18639	0.409090909090909	1.84179841897233	0.00410164640583794	0.0205401514564725
GO:0019888	protein phosphatase regulator activity	36/4140	107/18639	0.336448598130841	1.51475010158472	0.00430951794266053	0.0214974790395508
GO:0033549	MAP kinase phosphatase activity	29/4140	82/18639	0.353658536585366	1.59223223753977	0.00444279782862671	0.0220767598665736
GO:0019003	GDP binding	27/4140	75/18639	0.36	1.62078260869565	0.0044931853005566	0.0222412672377552
GO:0008174	mRNA methyltransferase activity	8/4140	14/18639	0.571428571428571	2.57267080745342	0.00479530733709292	0.023377123268328
GO:0061665	SUMO ligase activity	8/4140	14/18639	0.571428571428571	2.57267080745342	0.00479530733709292	0.023377123268328
GO:0070742	C2H2 zinc finger domain binding	8/4140	14/18639	0.571428571428571	2.57267080745342	0.00479530733709292	0.023377123268328
GO:0098847	sequence-specific single stranded DNA binding	8/4140	14/18639	0.571428571428571	2.57267080745342	0.00479530733709292	0.023377123268328
GO:0017116	single-stranded DNA helicase activity	22/4140	58/18639	0.379310344827586	1.70772113943028	0.00482635238566447	0.0234396812088686
GO:0036121	double-stranded DNA helicase activity	19/4140	48/18639	0.395833333333333	1.78211050724638	0.00497993940342145	0.0240044270119978
GO:0043138	3'-5' DNA helicase activity	19/4140	48/18639	0.395833333333333	1.78211050724638	0.00497993940342145	0.0240044270119978
GO:0016791	phosphatase activity	79/4140	273/18639	0.289377289377289	1.30282688326167	0.00533710888928971	0.0256300714198353
GO:0032183	SUMO binding	9/4140	17/18639	0.529411764705882	2.38350383631714	0.00545389152228194	0.0259968829228773
GO:0051787	misfolded protein binding	9/4140	17/18639	0.529411764705882	2.38350383631714	0.00545389152228194	0.0259968829228773
GO:0035198	miRNA binding	17/4140	42/18639	0.404761904761905	1.82230848861284	0.00592234953103864	0.0281256968503569
GO:0017018	myosin phosphatase activity	29/4140	84/18639	0.345238095238095	1.55432194616977	0.00653676866031384	0.030929489947882
GO:0000340	RNA 7-methylguanosine cap binding	7/4140	12/18639	0.583333333333333	2.62626811594203	0.00722071980174337	0.0335489761185694
GO:0005095	GTPase inhibitor activity	7/4140	12/18639	0.583333333333333	2.62626811594203	0.00722071980174337	0.0335489761185694
GO:0016273	arginine N-methyltransferase activity	7/4140	12/18639	0.583333333333333	2.62626811594203	0.00722071980174337	0.0335489761185694
GO:0016274	protein-arginine N-methyltransferase activity	7/4140	12/18639	0.583333333333333	2.62626811594203	0.00722071980174337	0.0335489761185694
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	7/4140	12/18639	0.583333333333333	2.62626811594203	0.00722071980174337	0.0335489761185694
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	67/4140	229/18639	0.292576419213974	1.31722992215683	0.00742830568318743	0.0343893144397922
GO:0016251	RNA polymerase II general transcription initiation factor activity	20/4140	53/18639	0.377358490566038	1.69893355209188	0.00749975462152968	0.0345956422864111
GO:0008187	poly-pyrimidine tract binding	13/4140	30/18639	0.433333333333333	1.95094202898551	0.0079378130440029	0.0363557487104332
GO:0032452	histone demethylase activity	13/4140	30/18639	0.433333333333333	1.95094202898551	0.0079378130440029	0.0363557487104332
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	39/4140	122/18639	0.319672131147541	1.43921952957947	0.00804992611057711	0.0367384925684849
GO:0141050	histone H3K deacetylase activity	8/4140	15/18639	0.533333333333333	2.40115942028985	0.00829038033726838	0.037569434838255
GO:0141051	histone H4K deacetylase activity	8/4140	15/18639	0.533333333333333	2.40115942028985	0.00829038033726838	0.037569434838255
GO:0048027	mRNA 5'-UTR binding	11/4140	24/18639	0.458333333333333	2.06349637681159	0.00870470016067236	0.0393085933571415
GO:0009931	calcium-dependent protein serine/threonine kinase activity	10/4140	21/18639	0.476190476190476	2.14389233954451	0.00887285930053656	0.0397887453651239
GO:0035613	RNA stem-loop binding	10/4140	21/18639	0.476190476190476	2.14389233954451	0.00887285930053656	0.0397887453651239
GO:0061749	forked DNA-dependent helicase activity	18/4140	47/18639	0.382978723404255	1.72423681776133	0.00917602168842296	0.0410053469201401
GO:0019213	deacetylase activity	15/4140	37/18639	0.405405405405405	1.82520564042303	0.00931479231732811	0.0414814453716307
GO:0008175	tRNA methyltransferase activity	14/4140	34/18639	0.411764705882353	1.85383631713555	0.0101203246219663	0.0448104244549112
GO:0001046	core promoter sequence-specific DNA binding	17/4140	44/18639	0.386363636363636	1.73947628458498	0.0101319607741874	0.0448104244549112
GO:0016410	N-acyltransferase activity	31/4140	94/18639	0.329787234042553	1.48475948196115	0.0105278099581298	0.046401682931894
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	6/4140	10/18639	0.6	2.70130434782609	0.0108913728676676	0.0467648031215919
GO:0008641	ubiquitin-like modifier activating enzyme activity	6/4140	10/18639	0.6	2.70130434782609	0.0108913728676676	0.0467648031215919
GO:0016427	tRNA (cytidine) methyltransferase activity	6/4140	10/18639	0.6	2.70130434782609	0.0108913728676676	0.0467648031215919
GO:0030957	Tat protein binding	6/4140	10/18639	0.6	2.70130434782609	0.0108913728676676	0.0467648031215919
GO:0031996	thioesterase binding	6/4140	10/18639	0.6	2.70130434782609	0.0108913728676676	0.0467648031215919
GO:0043422	protein kinase B binding	6/4140	10/18639	0.6	2.70130434782609	0.0108913728676676	0.0467648031215919
GO:0050815	phosphoserine residue binding	6/4140	10/18639	0.6	2.70130434782609	0.0108913728676676	0.0467648031215919
GO:0005164	tumor necrosis factor receptor binding	13/4140	31/18639	0.419354838709677	1.88800841514727	0.0109372227968913	0.0467648031215919
GO:0140457	protein demethylase activity	13/4140	31/18639	0.419354838709677	1.88800841514727	0.0109372227968913	0.0467648031215919
GO:0009378	four-way junction helicase activity	18/4140	48/18639	0.375	1.6883152173913	0.0116936710594239	0.0498336246803925
GO:0141052	histone H3 demethylase activity	12/4140	28/18639	0.428571428571429	1.92950310559006	0.0117366921590587	0.0498518904577842
GO:0019209	kinase activator activity	45/4140	148/18639	0.304054054054054	1.36890423031727	0.0124584300893778	0.0526338792632079
GO:0008139	nuclear localization sequence binding	11/4140	25/18639	0.44	1.98095652173913	0.0124734523506437	0.0526338792632079
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	7/4140	13/18639	0.538461538461538	2.4242474916388	0.0126704264549574	0.0532903230311445
GO:0004715	non-membrane spanning protein tyrosine kinase activity	17/4140	45/18639	0.377777777777778	1.70082125603865	0.0129814250352384	0.0542438117543891
GO:0051539	4 iron, 4 sulfur cluster binding	17/4140	45/18639	0.377777777777778	1.70082125603865	0.0129814250352384	0.0542438117543891
GO:0050321	tau-protein kinase activity	10/4140	22/18639	0.454545454545455	2.04644268774704	0.0130771170002225	0.0542911276751171
GO:0140035	ubiquitin-like protein reader activity	10/4140	22/18639	0.454545454545455	2.04644268774704	0.0130771170002225	0.0542911276751171
GO:0003688	DNA replication origin binding	8/4140	16/18639	0.5	2.25108695652174	0.0133897076083846	0.055410140488717
GO:0140036	ubiquitin-modified protein reader activity	9/4140	19/18639	0.473684210526316	2.13260869565217	0.0134387213740109	0.0554347256677949
GO:0043015	gamma-tubulin binding	14/4140	35/18639	0.4	1.80086956521739	0.013484475701158	0.0554457515252089
GO:0030515	snoRNA binding	13/4140	32/18639	0.40625	1.82900815217391	0.0147456244791867	0.0602464085863915
GO:0070717	poly-purine tract binding	13/4140	32/18639	0.40625	1.82900815217391	0.0147456244791867	0.0602464085863915
GO:0042578	phosphoric ester hydrolase activity	98/4140	363/18639	0.269972451790634	1.21546292969218	0.0172335369479442	0.0701884875063425
GO:0050681	nuclear androgen receptor binding	11/4140	26/18639	0.423076923076923	1.90476588628763	0.0173613839676824	0.0704861235533352
GO:0004712	protein serine/threonine/tyrosine kinase activity	16/4140	43/18639	0.372093023255814	1.67522750252781	0.0183080589035346	0.0737743827058286
GO:0048156	tau protein binding	16/4140	43/18639	0.372093023255814	1.67522750252781	0.0183080589035346	0.0737743827058286
GO:0032813	tumor necrosis factor receptor superfamily binding	18/4140	50/18639	0.36	1.62078260869565	0.0183432808592581	0.0737743827058286
GO:0003735	structural constituent of ribosome	51/4140	175/18639	0.291428571428571	1.31206211180124	0.0189987181844532	0.0761724308516861
GO:0071889	14-3-3 protein binding	13/4140	33/18639	0.393939393939394	1.7735836627141	0.0194875522577336	0.0772135806379926
GO:0140311	protein sequestering activity	13/4140	33/18639	0.393939393939394	1.7735836627141	0.0194875522577336	0.0772135806379926
GO:0140416	transcription regulator inhibitor activity	13/4140	33/18639	0.393939393939394	1.7735836627141	0.0194875522577336	0.0772135806379926
GO:0140031	phosphorylation-dependent protein binding	6/4140	11/18639	0.545454545454545	2.45573122529644	0.019498378948988	0.0772135806379926
GO:0043024	ribosomal small subunit binding	9/4140	20/18639	0.45	2.02597826086957	0.0197003821905669	0.0775363666032405
GO:0061608	nuclear import signal receptor activity	9/4140	20/18639	0.45	2.02597826086957	0.0197003821905669	0.0775363666032405
GO:0003925	G protein activity	19/4140	54/18639	0.351851851851852	1.58409822866345	0.0201521525826105	0.0790726230909137
GO:0005092	GDP-dissociation inhibitor activity	8/4140	17/18639	0.470588235294118	2.11867007672634	0.020443766351587	0.0799730312902505
GO:0030983	mismatched DNA binding	7/4140	14/18639	0.5	2.25108695652174	0.020545545572822	0.0801276277340059
GO:0019843	rRNA binding	22/4140	65/18639	0.338461538461538	1.5238127090301	0.0208547722877374	0.0808436504045725
GO:0160215	deacylase activity	22/4140	65/18639	0.338461538461538	1.5238127090301	0.0208547722877374	0.0808436504045725
GO:0000049	tRNA binding	26/4140	80/18639	0.325	1.46320652173913	0.0218344283592783	0.0843871150101836
GO:0001223	transcription coactivator binding	16/4140	44/18639	0.363636363636364	1.63715415019763	0.0229801149774472	0.0885491256765705
GO:0008266	poly(U) RNA binding	11/4140	27/18639	0.407407407407407	1.83421900161031	0.0235422684303929	0.0904444760295989
GO:0035035	histone acetyltransferase binding	10/4140	24/18639	0.416666666666667	1.87590579710145	0.0256914609394414	0.0979667696468297
GO:0001727	lipid kinase activity	15/4140	41/18639	0.365853658536585	1.64713679745493	0.0257286465739149	0.0979667696468297
GO:0140318	protein transporter activity	15/4140	41/18639	0.365853658536585	1.64713679745493	0.0257286465739149	0.0979667696468297
GO:0031593	polyubiquitin modification-dependent protein binding	20/4140	59/18639	0.338983050847458	1.52616064848931	0.0263277547839881	0.099952272586999
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9/4140	21/18639	0.428571428571429	1.92950310559006	0.0278210243580897	0.104694907452811
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	9/4140	21/18639	0.428571428571429	1.92950310559006	0.0278210243580897	0.104694907452811
GO:0070182	DNA polymerase binding	9/4140	21/18639	0.428571428571429	1.92950310559006	0.0278210243580897	0.104694907452811
GO:0035091	phosphatidylinositol binding	77/4140	284/18639	0.27112676056338	1.22065982853644	0.0287807179822257	0.107990624032433
GO:0070628	proteasome binding	8/4140	18/18639	0.444444444444444	2.00096618357488	0.0297748064665748	0.111395860239773
GO:0051537	2 iron, 2 sulfur cluster binding	11/4140	28/18639	0.392857142857143	1.76871118012422	0.0311811707236092	0.115640704319281
GO:0031386	protein tag activity	7/4140	15/18639	0.466666666666667	2.10101449275362	0.0312688151539314	0.115640704319281
GO:0140776	protein-containing complex destabilizing activity	7/4140	15/18639	0.466666666666667	2.10101449275362	0.0312688151539314	0.115640704319281
GO:0141047	molecular tag activity	7/4140	15/18639	0.466666666666667	2.10101449275362	0.0312688151539314	0.115640704319281
GO:0000995	RNA polymerase III general transcription initiation factor activity	6/4140	12/18639	0.5	2.25108695652174	0.0317760380962327	0.116181139289351
GO:0005049	nuclear export signal receptor activity	6/4140	12/18639	0.5	2.25108695652174	0.0317760380962327	0.116181139289351
GO:0035197	siRNA binding	6/4140	12/18639	0.5	2.25108695652174	0.0317760380962327	0.116181139289351
GO:0141221	histone deacetylase activity, hydrolytic mechanism	6/4140	12/18639	0.5	2.25108695652174	0.0317760380962327	0.116181139289351
GO:0048487	beta-tubulin binding	15/4140	42/18639	0.357142857142857	1.60791925465839	0.0320229766372256	0.116752325586712
GO:0000149	SNARE binding	32/4140	106/18639	0.30188679245283	1.3591468416735	0.0343880360950527	0.125020910887946
GO:0031369	translation initiation factor binding	12/4140	32/18639	0.375	1.6883152173913	0.0361199098898991	0.130947391629014
GO:0034062	5'-3' RNA polymerase activity	9/4140	22/18639	0.409090909090909	1.84179841897233	0.0380283448366132	0.137093780965606
GO:0097747	RNA polymerase activity	9/4140	22/18639	0.409090909090909	1.84179841897233	0.0380283448366132	0.137093780965606
GO:0030295	protein kinase activator activity	40/4140	139/18639	0.287769784172662	1.29558961526431	0.0415701852981812	0.148918754358671
GO:0140101	catalytic activity, acting on a tRNA	40/4140	139/18639	0.287769784172662	1.29558961526431	0.0415701852981812	0.148918754358671
GO:0120227	acyl-CoA binding	8/4140	19/18639	0.421052631578947	1.89565217391304	0.0416555956248031	0.148918754358671
GO:0032451	demethylase activity	14/4140	40/18639	0.35	1.57576086956522	0.0444124994992734	0.15789747750156
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	14/4140	40/18639	0.35	1.57576086956522	0.0444124994992734	0.15789747750156
GO:0000062	fatty-acyl-CoA binding	7/4140	16/18639	0.4375	1.96970108695652	0.0451747876893566	0.158852327202738
GO:0004708	MAP kinase kinase activity	7/4140	16/18639	0.4375	1.96970108695652	0.0451747876893566	0.158852327202738
GO:0017070	U6 snRNA binding	7/4140	16/18639	0.4375	1.96970108695652	0.0451747876893566	0.158852327202738
GO:0034450	ubiquitin-ubiquitin ligase activity	7/4140	16/18639	0.4375	1.96970108695652	0.0451747876893566	0.158852327202738
GO:0140313	molecular sequestering activity	18/4140	55/18639	0.327272727272727	1.47343873517787	0.047419777527555	0.166292244354123
GO:0046974	histone H3K9 methyltransferase activity	6/4140	13/18639	0.461538461538462	2.07792642140468	0.0481522766458972	0.167945745374714
GO:0097157	pre-mRNA intronic binding	6/4140	13/18639	0.461538461538462	2.07792642140468	0.0481522766458972	0.167945745374714
GO:0016303	1-phosphatidylinositol-3-kinase activity	5/4140	10/18639	0.5	2.25108695652174	0.0496676525022307	0.171287435459524
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	5/4140	10/18639	0.5	2.25108695652174	0.0496676525022307	0.171287435459524
GO:0042975	peroxisome proliferator activated receptor binding	5/4140	10/18639	0.5	2.25108695652174	0.0496676525022307	0.171287435459524
GO:0051864	histone H3K36 demethylase activity	5/4140	10/18639	0.5	2.25108695652174	0.0496676525022307	0.171287435459524
GO:1901981	phosphatidylinositol phosphate binding	51/4140	185/18639	0.275675675675676	1.24113983548766	0.0497758359455027	0.171287435459524
GO:0003887	DNA-directed DNA polymerase activity	9/4140	23/18639	0.391304347826087	1.7617202268431	0.0505092239791081	0.172428040480404
GO:0042171	lysophosphatidic acid acyltransferase activity	9/4140	23/18639	0.391304347826087	1.7617202268431	0.0505092239791081	0.172428040480404
GO:0071617	lysophospholipid acyltransferase activity	9/4140	23/18639	0.391304347826087	1.7617202268431	0.0505092239791081	0.172428040480404
GO:0004725	protein tyrosine phosphatase activity	29/4140	98/18639	0.295918367346939	1.3322759538598	0.0538297176105505	0.183229591336196
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	14/4140	41/18639	0.341463414634146	1.5373276776246	0.0541004232383483	0.183229591336196
GO:0042287	MHC protein binding	14/4140	41/18639	0.341463414634146	1.5373276776246	0.0541004232383483	0.183229591336196
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	8/4140	20/18639	0.4	1.80086956521739	0.0562924045809605	0.189655300250514
GO:0016004	phospholipase activator activity	8/4140	20/18639	0.4	1.80086956521739	0.0562924045809605	0.189655300250514
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	12/4140	34/18639	0.352941176470588	1.58900255754476	0.056717460812084	0.190092114753
GO:0030332	cyclin binding	12/4140	34/18639	0.352941176470588	1.58900255754476	0.056717460812084	0.190092114753
GO:0140303	intramembrane lipid transporter activity	15/4140	45/18639	0.333333333333333	1.50072463768116	0.0575235513771635	0.192293014603661
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	7/4140	17/18639	0.411764705882353	1.85383631713555	0.0624865026257955	0.206735549818506
GO:0045125	bioactive lipid receptor activity	7/4140	17/18639	0.411764705882353	1.85383631713555	0.0624865026257955	0.206735549818506
GO:1901567	fatty acid derivative binding	7/4140	17/18639	0.411764705882353	1.85383631713555	0.0624865026257955	0.206735549818506
GO:1990226	histone methyltransferase binding	7/4140	17/18639	0.411764705882353	1.85383631713555	0.0624865026257955	0.206735549818506
GO:0016504	peptidase activator activity	18/4140	57/18639	0.315789473684211	1.42173913043478	0.0652784510646487	0.214692488579369
GO:0001091	RNA polymerase II general transcription initiation factor binding	9/4140	24/18639	0.375	1.6883152173913	0.0653998818029081	0.214692488579369
GO:0060229	lipase activator activity	9/4140	24/18639	0.375	1.6883152173913	0.0653998818029081	0.214692488579369
GO:0051117	ATPase binding	25/4140	84/18639	0.297619047619048	1.33993271221532	0.0655587785638631	0.214692488579369
GO:0034236	protein kinase A catalytic subunit binding	6/4140	14/18639	0.428571428571429	1.92950310559006	0.0688573249507036	0.223786306089787
GO:0042043	neurexin family protein binding	6/4140	14/18639	0.428571428571429	1.92950310559006	0.0688573249507036	0.223786306089787
GO:0071933	Arp2/3 complex binding	6/4140	14/18639	0.428571428571429	1.92950310559006	0.0688573249507036	0.223786306089787
GO:0034061	DNA polymerase activity	12/4140	35/18639	0.342857142857143	1.54360248447205	0.0694778100812999	0.225234109759781
GO:0097718	disordered domain specific binding	10/4140	28/18639	0.357142857142857	1.60791925465839	0.0728484336276986	0.234255023494461
GO:0051287	NAD binding	17/4140	54/18639	0.314814814814815	1.41735104669887	0.0736858119293399	0.234255023494461
GO:0072542	protein phosphatase activator activity	8/4140	21/18639	0.380952380952381	1.71511387163561	0.0738132539488811	0.234255023494461
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	26/4140	89/18639	0.292134831460674	1.3152418172936	0.0745495293131866	0.234255023494461
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	26/4140	89/18639	0.292134831460674	1.3152418172936	0.0745495293131866	0.234255023494461
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	5/4140	11/18639	0.454545454545455	2.04644268774704	0.0748087137965995	0.234255023494461
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	5/4140	11/18639	0.454545454545455	2.04644268774704	0.0748087137965995	0.234255023494461
GO:0004143	ATP-dependent diacylglycerol kinase activity	5/4140	11/18639	0.454545454545455	2.04644268774704	0.0748087137965995	0.234255023494461
GO:0019107	myristoyltransferase activity	5/4140	11/18639	0.454545454545455	2.04644268774704	0.0748087137965995	0.234255023494461
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	5/4140	11/18639	0.454545454545455	2.04644268774704	0.0748087137965995	0.234255023494461
GO:0032794	GTPase activating protein binding	5/4140	11/18639	0.454545454545455	2.04644268774704	0.0748087137965995	0.234255023494461
GO:0042608	T cell receptor binding	5/4140	11/18639	0.454545454545455	2.04644268774704	0.0748087137965995	0.234255023494461
GO:0140537	transcription regulator activator activity	5/4140	11/18639	0.454545454545455	2.04644268774704	0.0748087137965995	0.234255023494461
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	5/4140	11/18639	0.454545454545455	2.04644268774704	0.0748087137965995	0.234255023494461
GO:0022884	macromolecule transmembrane transporter activity	11/4140	32/18639	0.34375	1.5476222826087	0.0789498276785995	0.246622398597955
GO:0003746	translation elongation factor activity	7/4140	18/18639	0.388888888888889	1.75084541062802	0.0833030365452994	0.2583397783947
GO:0008409	5'-3' exonuclease activity	7/4140	18/18639	0.388888888888889	1.75084541062802	0.0833030365452994	0.2583397783947
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	7/4140	18/18639	0.388888888888889	1.75084541062802	0.0833030365452994	0.2583397783947
GO:0140793	histone H2AXY142 phosphatase activity	26/4140	90/18639	0.288888888888889	1.30062801932367	0.0835046135793712	0.258342398261179
GO:0055106	ubiquitin-protein transferase regulator activity	12/4140	36/18639	0.333333333333333	1.50072463768116	0.083957578233178	0.25912087094988
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	10/4140	29/18639	0.344827586206897	1.55247376311844	0.0899120161189282	0.27617366287604
GO:0097472	cyclin-dependent protein kinase activity	10/4140	29/18639	0.344827586206897	1.55247376311844	0.0899120161189282	0.27617366287604
GO:0050700	CARD domain binding	6/4140	15/18639	0.4	1.80086956521739	0.093916331481885	0.287786472898062
GO:0008649	rRNA methyltransferase activity	8/4140	22/18639	0.363636363636364	1.63715415019763	0.0942617734416055	0.288158913110086
GO:0030159	signaling receptor complex adaptor activity	16/4140	52/18639	0.307692307692308	1.38528428093645	0.0964925956020718	0.294279551042337
GO:0004529	DNA exonuclease activity	9/4140	26/18639	0.346153846153846	1.55844481605351	0.102664799005949	0.309436993725191
GO:0008143	poly(A) binding	9/4140	26/18639	0.346153846153846	1.55844481605351	0.102664799005949	0.309436993725191
GO:0008157	protein phosphatase 1 binding	9/4140	26/18639	0.346153846153846	1.55844481605351	0.102664799005949	0.309436993725191
GO:0034237	protein kinase A regulatory subunit binding	9/4140	26/18639	0.346153846153846	1.55844481605351	0.102664799005949	0.309436993725191
GO:0052742	phosphatidylinositol kinase activity	9/4140	26/18639	0.346153846153846	1.55844481605351	0.102664799005949	0.309436993725191
GO:0042169	SH2 domain binding	13/4140	41/18639	0.317073170731707	1.42751855779427	0.103845559158833	0.312264566909856
GO:0034452	dynactin binding	5/4140	12/18639	0.416666666666667	1.87590579710145	0.105546339296862	0.3144401358219
GO:0035014	phosphatidylinositol 3-kinase regulator activity	5/4140	12/18639	0.416666666666667	1.87590579710145	0.105546339296862	0.3144401358219
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	5/4140	12/18639	0.416666666666667	1.87590579710145	0.105546339296862	0.3144401358219
GO:0070679	inositol 1,4,5 trisphosphate binding	5/4140	12/18639	0.416666666666667	1.87590579710145	0.105546339296862	0.3144401358219
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	18/4140	61/18639	0.295081967213115	1.32851033499644	0.113462843053445	0.337244062378254
GO:0043274	phospholipase binding	8/4140	23/18639	0.347826086956522	1.56597353497164	0.117596466488271	0.347125349473406
GO:0140102	catalytic activity, acting on a rRNA	8/4140	23/18639	0.347826086956522	1.56597353497164	0.117596466488271	0.347125349473406
GO:0140103	catalytic activity, acting on a glycoprotein	8/4140	23/18639	0.347826086956522	1.56597353497164	0.117596466488271	0.347125349473406
GO:0031492	nucleosomal DNA binding	13/4140	42/18639	0.30952380952381	1.39353002070393	0.121196709643627	0.356934016730772
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	6/4140	16/18639	0.375	1.6883152173913	0.123161257757402	0.357807085177825
GO:0008296	3'-5'-DNA exonuclease activity	6/4140	16/18639	0.375	1.6883152173913	0.123161257757402	0.357807085177825
GO:0022858	alanine transmembrane transporter activity	6/4140	16/18639	0.375	1.6883152173913	0.123161257757402	0.357807085177825
GO:0030275	LRR domain binding	6/4140	16/18639	0.375	1.6883152173913	0.123161257757402	0.357807085177825
GO:0097027	ubiquitin-protein transferase activator activity	6/4140	16/18639	0.375	1.6883152173913	0.123161257757402	0.357807085177825
GO:0140328	floppase activity	6/4140	16/18639	0.375	1.6883152173913	0.123161257757402	0.357807085177825
GO:0030291	protein serine/threonine kinase inhibitor activity	14/4140	46/18639	0.304347826086957	1.37022684310019	0.123544284286044	0.358111472694006
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	9/4140	27/18639	0.333333333333333	1.50072463768116	0.125013564356519	0.360745420015336
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	9/4140	27/18639	0.333333333333333	1.50072463768116	0.125013564356519	0.360745420015336
GO:0097110	scaffold protein binding	20/4140	70/18639	0.285714285714286	1.28633540372671	0.128674189132638	0.370478034482561
GO:0008327	methyl-CpG binding	10/4140	31/18639	0.32258064516129	1.4523141654979	0.130561563810507	0.375073063893129
GO:0005154	epidermal growth factor receptor binding	11/4140	35/18639	0.314285714285714	1.41496894409938	0.134719177651545	0.38333077147194
GO:0016408	C-acyltransferase activity	7/4140	20/18639	0.35	1.57576086956522	0.13522313150603	0.38333077147194
GO:0016505	peptidase activator activity involved in apoptotic process	7/4140	20/18639	0.35	1.57576086956522	0.13522313150603	0.38333077147194
GO:0030742	GTP-dependent protein binding	7/4140	20/18639	0.35	1.57576086956522	0.13522313150603	0.38333077147194
GO:0042288	MHC class I protein binding	7/4140	20/18639	0.35	1.57576086956522	0.13522313150603	0.38333077147194
GO:0052745	inositol phosphate phosphatase activity	7/4140	20/18639	0.35	1.57576086956522	0.13522313150603	0.38333077147194
GO:0019855	calcium channel inhibitor activity	5/4140	13/18639	0.384615384615385	1.73160535117057	0.141417628453714	0.397389711397227
GO:0035673	oligopeptide transmembrane transporter activity	5/4140	13/18639	0.384615384615385	1.73160535117057	0.141417628453714	0.397389711397227
GO:0051011	microtubule minus-end binding	5/4140	13/18639	0.384615384615385	1.73160535117057	0.141417628453714	0.397389711397227
GO:0140666	annealing activity	5/4140	13/18639	0.384615384615385	1.73160535117057	0.141417628453714	0.397389711397227
GO:0005048	signal sequence binding	15/4140	51/18639	0.294117647058824	1.32416879795396	0.142845718026553	0.400528189760727
GO:0070840	dynein complex binding	8/4140	24/18639	0.333333333333333	1.50072463768116	0.143694758830952	0.401160855998776
GO:0140612	DNA damage sensor activity	8/4140	24/18639	0.333333333333333	1.50072463768116	0.143694758830952	0.401160855998776
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	6/4140	17/18639	0.352941176470588	1.58900255754476	0.156256578738278	0.431398598346449
GO:0031489	myosin V binding	6/4140	17/18639	0.352941176470588	1.58900255754476	0.156256578738278	0.431398598346449
GO:0004177	aminopeptidase activity	12/4140	40/18639	0.3	1.35065217391304	0.15913840873324	0.431398598346449
GO:0015036	disulfide oxidoreductase activity	12/4140	40/18639	0.3	1.35065217391304	0.15913840873324	0.431398598346449
GO:0005548	phospholipid transporter activity	19/4140	68/18639	0.279411764705882	1.25796035805627	0.160096854601916	0.431398598346449
GO:0019205	nucleobase-containing compound kinase activity	13/4140	44/18639	0.295454545454545	1.33018774703557	0.160496530821702	0.431398598346449
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	17/4140	60/18639	0.283333333333333	1.27561594202899	0.161336472009528	0.431398598346449
GO:0005131	growth hormone receptor binding	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0005522	profilin binding	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0005528	FK506 binding	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0008140	cAMP response element binding protein binding	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0032356	oxidized DNA binding	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0033204	ribonuclease P RNA binding	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0051880	G-quadruplex DNA binding	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0097177	mitochondrial ribosome binding	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0140940	histone H2A methyltransferase activity	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:1905394	retromer complex binding	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:1990259	histone H2AQ104 methyltransferase activity	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:1990757	ubiquitin ligase activator activity	4/4140	10/18639	0.4	1.80086956521739	0.162905764410547	0.431398598346449
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	34/4140	130/18639	0.261538461538462	1.17749163879599	0.163395000115944	0.431805677924475
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	7/4140	21/18639	0.333333333333333	1.50072463768116	0.165928070284605	0.437601283721898
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	8/4140	25/18639	0.32	1.44069565217391	0.172360944013608	0.450871005986816
GO:0019211	phosphatase activator activity	8/4140	25/18639	0.32	1.44069565217391	0.172360944013608	0.450871005986816
GO:0042974	nuclear retinoic acid receptor binding	8/4140	25/18639	0.32	1.44069565217391	0.172360944013608	0.450871005986816
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	8/4140	25/18639	0.32	1.44069565217391	0.172360944013608	0.450871005986816
GO:0004629	phospholipase C activity	9/4140	29/18639	0.310344827586207	1.3972263868066	0.176638469274546	0.461123143927668
GO:0004519	endonuclease activity	33/4140	127/18639	0.259842519685039	1.16985621362547	0.178102212198011	0.464003131779029
GO:0120013	lipid transfer activity	18/4140	65/18639	0.276923076923077	1.24675585284281	0.178640678985192	0.464465765361499
GO:0019239	deaminase activity	10/4140	33/18639	0.303030303030303	1.36429512516469	0.179416556687044	0.464796496851252
GO:0016860	intramolecular oxidoreductase activity	15/4140	53/18639	0.283018867924528	1.27420016406891	0.181645692839529	0.464796496851252
GO:0051018	protein kinase A binding	15/4140	53/18639	0.283018867924528	1.27420016406891	0.181645692839529	0.464796496851252
GO:0005545	1-phosphatidylinositol binding	5/4140	14/18639	0.357142857142857	1.60791925465839	0.181728908177609	0.464796496851252
GO:0008474	palmitoyl-(protein) hydrolase activity	5/4140	14/18639	0.357142857142857	1.60791925465839	0.181728908177609	0.464796496851252
GO:0046030	inositol trisphosphate phosphatase activity	5/4140	14/18639	0.357142857142857	1.60791925465839	0.181728908177609	0.464796496851252
GO:0098599	palmitoyl hydrolase activity	5/4140	14/18639	0.357142857142857	1.60791925465839	0.181728908177609	0.464796496851252
GO:1990825	sequence-specific mRNA binding	5/4140	14/18639	0.357142857142857	1.60791925465839	0.181728908177609	0.464796496851252
GO:0016877	ligase activity, forming carbon-sulfur bonds	12/4140	41/18639	0.292682926829268	1.31770943796394	0.182018208557134	0.464796496851252
GO:0000400	four-way junction DNA binding	6/4140	18/18639	0.333333333333333	1.50072463768116	0.192733349834768	0.486368276935973
GO:0000900	mRNA regulatory element binding translation repressor activity	6/4140	18/18639	0.333333333333333	1.50072463768116	0.192733349834768	0.486368276935973
GO:0008525	phosphatidylcholine transporter activity	6/4140	18/18639	0.333333333333333	1.50072463768116	0.192733349834768	0.486368276935973
GO:0017128	phospholipid scramblase activity	6/4140	18/18639	0.333333333333333	1.50072463768116	0.192733349834768	0.486368276935973
GO:0031690	adrenergic receptor binding	6/4140	18/18639	0.333333333333333	1.50072463768116	0.192733349834768	0.486368276935973
GO:0050811	GABA receptor binding	6/4140	18/18639	0.333333333333333	1.50072463768116	0.192733349834768	0.486368276935973
GO:0061133	endopeptidase activator activity	7/4140	22/18639	0.318181818181818	1.43250988142292	0.199372342144671	0.502137386184327
GO:0004435	phosphatidylinositol phospholipase C activity	8/4140	26/18639	0.307692307692308	1.38528428093645	0.203337008461456	0.509133715739094
GO:0070412	R-SMAD binding	8/4140	26/18639	0.307692307692308	1.38528428093645	0.203337008461456	0.509133715739094
GO:0097602	cullin family protein binding	8/4140	26/18639	0.307692307692308	1.38528428093645	0.203337008461456	0.509133715739094
GO:0030276	clathrin binding	13/4140	46/18639	0.282608695652174	1.27235349716446	0.205473994106204	0.512695868466905
GO:0051721	protein phosphatase 2A binding	9/4140	30/18639	0.3	1.35065217391304	0.205556385492559	0.512695868466905
GO:0016859	cis-trans isomerase activity	12/4140	42/18639	0.285714285714286	1.28633540372671	0.206346808122537	0.512741910623925
GO:0052866	phosphatidylinositol phosphate phosphatase activity	10/4140	34/18639	0.294117647058824	1.32416879795396	0.206583977038415	0.512741910623925
GO:0043531	ADP binding	11/4140	38/18639	0.289473684210526	1.30326086956522	0.206770047873984	0.512741910623925
GO:0008526	phosphatidylinositol transfer activity	4/4140	11/18639	0.363636363636364	1.63715415019763	0.213246936189946	0.520775724623264
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	4/4140	11/18639	0.363636363636364	1.63715415019763	0.213246936189946	0.520775724623264
GO:0015173	aromatic amino acid transmembrane transporter activity	4/4140	11/18639	0.363636363636364	1.63715415019763	0.213246936189946	0.520775724623264
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/4140	11/18639	0.363636363636364	1.63715415019763	0.213246936189946	0.520775724623264
GO:0019206	nucleoside kinase activity	4/4140	11/18639	0.363636363636364	1.63715415019763	0.213246936189946	0.520775724623264
GO:0034511	U3 snoRNA binding	4/4140	11/18639	0.363636363636364	1.63715415019763	0.213246936189946	0.520775724623264
GO:0034713	type I transforming growth factor beta receptor binding	4/4140	11/18639	0.363636363636364	1.63715415019763	0.213246936189946	0.520775724623264
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	4/4140	11/18639	0.363636363636364	1.63715415019763	0.213246936189946	0.520775724623264
GO:0000774	adenyl-nucleotide exchange factor activity	5/4140	15/18639	0.333333333333333	1.50072463768116	0.225635196525471	0.54482645014687
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	5/4140	15/18639	0.333333333333333	1.50072463768116	0.225635196525471	0.54482645014687
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	5/4140	15/18639	0.333333333333333	1.50072463768116	0.225635196525471	0.54482645014687
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	5/4140	15/18639	0.333333333333333	1.50072463768116	0.225635196525471	0.54482645014687
GO:0055105	ubiquitin-protein transferase inhibitor activity	5/4140	15/18639	0.333333333333333	1.50072463768116	0.225635196525471	0.54482645014687
GO:0120283	protein serine/threonine kinase binding	5/4140	15/18639	0.333333333333333	1.50072463768116	0.225635196525471	0.54482645014687
GO:0043495	protein-membrane adaptor activity	13/4140	47/18639	0.276595744680851	1.24528214616096	0.229846761481275	0.553956520648691
GO:0008375	acetylglucosaminyltransferase activity	12/4140	43/18639	0.27906976744186	1.25642062689585	0.231991668113302	0.554023356312317
GO:0008301	DNA binding, bending	6/4140	19/18639	0.315789473684211	1.42173913043478	0.232026875720543	0.554023356312317
GO:0042800	histone H3K4 methyltransferase activity	6/4140	19/18639	0.315789473684211	1.42173913043478	0.232026875720543	0.554023356312317
GO:0046624	sphingolipid transporter activity	6/4140	19/18639	0.315789473684211	1.42173913043478	0.232026875720543	0.554023356312317
GO:1990380	K48-linked deubiquitinase activity	6/4140	19/18639	0.315789473684211	1.42173913043478	0.232026875720543	0.554023356312317
GO:0000217	DNA secondary structure binding	11/4140	39/18639	0.282051282051282	1.26984392419175	0.233858077604716	0.555305066194225
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	11/4140	39/18639	0.282051282051282	1.26984392419175	0.233858077604716	0.555305066194225
GO:0016776	phosphotransferase activity, phosphate group as acceptor	11/4140	39/18639	0.282051282051282	1.26984392419175	0.233858077604716	0.555305066194225
GO:0016411	acylglycerol O-acyltransferase activity	9/4140	31/18639	0.290322580645161	1.30708274894811	0.23623608527158	0.559076823569315
GO:0008320	protein transmembrane transporter activity	8/4140	27/18639	0.296296296296296	1.33397745571659	0.236315300716167	0.559076823569315
GO:0001217	DNA-binding transcription repressor activity	67/4140	278/18639	0.241007194244604	1.08505630278386	0.242711253505719	0.573154831673138
GO:0002020	protease binding	34/4140	136/18639	0.25	1.12554347826087	0.244565210896179	0.576475139969564
GO:0004521	RNA endonuclease activity	19/4140	73/18639	0.26027397260274	1.17179868969625	0.25470506928334	0.599278654785481
GO:0016790	thiolester hydrolase activity	12/4140	44/18639	0.272727272727273	1.22786561264822	0.258802344597652	0.607807696162734
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	11/4140	40/18639	0.275	1.23809782608696	0.262200020969759	0.611662172557225
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	10/4140	36/18639	0.277777777777778	1.2506038647343	0.265435902715293	0.611662172557225
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	10/4140	36/18639	0.277777777777778	1.2506038647343	0.265435902715293	0.611662172557225
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	10/4140	36/18639	0.277777777777778	1.2506038647343	0.265435902715293	0.611662172557225
GO:0003995	acyl-CoA dehydrogenase activity	4/4140	12/18639	0.333333333333333	1.50072463768116	0.267097234636488	0.611662172557225
GO:0004000	adenosine deaminase activity	4/4140	12/18639	0.333333333333333	1.50072463768116	0.267097234636488	0.611662172557225
GO:0004126	cytidine deaminase activity	4/4140	12/18639	0.333333333333333	1.50072463768116	0.267097234636488	0.611662172557225
GO:0004526	ribonuclease P activity	4/4140	12/18639	0.333333333333333	1.50072463768116	0.267097234636488	0.611662172557225
GO:0005078	MAP-kinase scaffold activity	4/4140	12/18639	0.333333333333333	1.50072463768116	0.267097234636488	0.611662172557225
GO:0005527	macrolide binding	4/4140	12/18639	0.333333333333333	1.50072463768116	0.267097234636488	0.611662172557225
GO:0016423	tRNA (guanine) methyltransferase activity	4/4140	12/18639	0.333333333333333	1.50072463768116	0.267097234636488	0.611662172557225
GO:0036009	protein-glutamine N-methyltransferase activity	4/4140	12/18639	0.333333333333333	1.50072463768116	0.267097234636488	0.611662172557225
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	4/4140	12/18639	0.333333333333333	1.50072463768116	0.267097234636488	0.611662172557225
GO:0097677	STAT family protein binding	4/4140	12/18639	0.333333333333333	1.50072463768116	0.267097234636488	0.611662172557225
GO:0008378	galactosyltransferase activity	9/4140	32/18639	0.28125	1.26623641304348	0.268407031906799	0.613569893541831
GO:0004707	MAP kinase activity	5/4140	16/18639	0.3125	1.40692934782609	0.272214259601866	0.617883160683601
GO:0015923	mannosidase activity	5/4140	16/18639	0.3125	1.40692934782609	0.272214259601866	0.617883160683601
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	5/4140	16/18639	0.3125	1.40692934782609	0.272214259601866	0.617883160683601
GO:0140327	flippase activity	5/4140	16/18639	0.3125	1.40692934782609	0.272214259601866	0.617883160683601
GO:0070300	phosphatidic acid binding	7/4140	24/18639	0.291666666666667	1.31313405797101	0.272807034943978	0.618138475304401
GO:0140664	ATP-dependent DNA damage sensor activity	6/4140	20/18639	0.3	1.35065217391304	0.273514194669619	0.618651614305448
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	64/4140	268/18639	0.238805970149254	1.07514600908501	0.27534181791115	0.621692841494122
GO:0035254	glutamate receptor binding	13/4140	49/18639	0.26530612244898	1.19445430346051	0.281725829228523	0.6349932438128
GO:0046332	SMAD binding	20/4140	79/18639	0.253164556962025	1.13979086406164	0.29207642952932	0.65717196644097
GO:0019956	chemokine binding	9/4140	33/18639	0.272727272727273	1.22786561264822	0.301778460114207	0.677816541303638
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	14/4140	54/18639	0.259259259259259	1.16723027375201	0.302894595878434	0.679138231525338
GO:0035250	UDP-galactosyltransferase activity	8/4140	29/18639	0.275862068965517	1.24197901049475	0.306881068697881	0.686879887676823
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	17/4140	67/18639	0.253731343283582	1.14234263465282	0.309575172876588	0.691707026896127
GO:0004709	MAP kinase kinase kinase activity	7/4140	25/18639	0.28	1.26060869565217	0.311869403639122	0.694422011217215
GO:0047617	fatty acyl-CoA hydrolase activity	7/4140	25/18639	0.28	1.26060869565217	0.311869403639122	0.694422011217215
GO:0051213	dioxygenase activity	23/4140	93/18639	0.247311827956989	1.11344086021505	0.316051391248013	0.702410526505528
GO:0005123	death receptor binding	6/4140	21/18639	0.285714285714286	1.28633540372671	0.316548644423626	0.702410526505528
GO:0016853	isomerase activity	43/4140	180/18639	0.238888888888889	1.0755193236715	0.32032978924403	0.706875638968889
GO:0004549	tRNA-specific ribonuclease activity	5/4140	17/18639	0.294117647058824	1.32416879795396	0.320529959961695	0.706875638968889
GO:0008429	phosphatidylethanolamine binding	5/4140	17/18639	0.294117647058824	1.32416879795396	0.320529959961695	0.706875638968889
GO:0005035	death receptor activity	4/4140	13/18639	0.307692307692308	1.38528428093645	0.322954837384388	0.706875638968889
GO:0005338	nucleotide-sugar transmembrane transporter activity	4/4140	13/18639	0.307692307692308	1.38528428093645	0.322954837384388	0.706875638968889
GO:0008253	5'-nucleotidase activity	4/4140	13/18639	0.307692307692308	1.38528428093645	0.322954837384388	0.706875638968889
GO:0019104	DNA N-glycosylase activity	4/4140	13/18639	0.307692307692308	1.38528428093645	0.322954837384388	0.706875638968889
GO:0140333	glycerophospholipid flippase activity	4/4140	13/18639	0.307692307692308	1.38528428093645	0.322954837384388	0.706875638968889
GO:0015035	protein-disulfide reductase activity	9/4140	34/18639	0.264705882352941	1.19175191815857	0.336048474021493	0.734285884661563
GO:0004536	DNA nuclease activity	16/4140	64/18639	0.25	1.12554347826087	0.340831604722364	0.743475042843531
GO:0016289	acyl-CoA hydrolase activity	7/4140	26/18639	0.269230769230769	1.2121237458194	0.351855022915104	0.762352549649392
GO:0043548	phosphatidylinositol 3-kinase binding	7/4140	26/18639	0.269230769230769	1.2121237458194	0.351855022915104	0.762352549649392
GO:0070006	metalloaminopeptidase activity	7/4140	26/18639	0.269230769230769	1.2121237458194	0.351855022915104	0.762352549649392
GO:0120014	phospholipid transfer activity	7/4140	26/18639	0.269230769230769	1.2121237458194	0.351855022915104	0.762352549649392
GO:1990782	protein tyrosine kinase binding	28/4140	117/18639	0.239316239316239	1.07744332961724	0.361162373129795	0.781203318013522
GO:0004706	JUN kinase kinase kinase activity	5/4140	18/18639	0.277777777777778	1.2506038647343	0.369682502318205	0.796953736153316
GO:0008308	voltage-gated monoatomic anion channel activity	5/4140	18/18639	0.277777777777778	1.2506038647343	0.369682502318205	0.796953736153316
GO:0019905	syntaxin binding	15/4140	61/18639	0.245901639344262	1.10709194583036	0.374828385438754	0.806695873009492
GO:0004705	JUN kinase activity	4/4140	14/18639	0.285714285714286	1.28633540372671	0.3794452090671	0.807417675104534
GO:0032454	histone H3K9 demethylase activity	4/4140	14/18639	0.285714285714286	1.28633540372671	0.3794452090671	0.807417675104534
GO:0044548	S100 protein binding	4/4140	14/18639	0.285714285714286	1.28633540372671	0.3794452090671	0.807417675104534
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	4/4140	14/18639	0.285714285714286	1.28633540372671	0.3794452090671	0.807417675104534
GO:0070273	phosphatidylinositol-4-phosphate binding	8/4140	31/18639	0.258064516129032	1.16185133239832	0.381114346401338	0.807417675104534
GO:0016248	channel inhibitor activity	11/4140	44/18639	0.25	1.12554347826087	0.384053028927703	0.807417675104534
GO:0001094	TFIID-class transcription factor complex binding	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0004445	inositol-polyphosphate 5-phosphatase activity	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0004955	prostaglandin receptor activity	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0005031	tumor necrosis factor receptor activity	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0005381	iron ion transmembrane transporter activity	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0008239	dipeptidyl-peptidase activity	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0016783	sulfurtransferase activity	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0016868	intramolecular phosphotransferase activity	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0043295	glutathione binding	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0140999	histone H3K4 trimethyltransferase activity	3/4140	10/18639	0.3	1.35065217391304	0.389593143931558	0.807417675104534
GO:0035255	ionotropic glutamate receptor binding	7/4140	27/18639	0.259259259259259	1.16723027375201	0.392293925684733	0.811707849447348
GO:0008171	O-methyltransferase activity	6/4140	23/18639	0.260869565217391	1.17448015122873	0.404727570731371	0.836090503260473
GO:0016409	palmitoyltransferase activity	9/4140	36/18639	0.25	1.12554347826087	0.406071494972531	0.837522458380845
GO:0141110	transporter inhibitor activity	11/4140	45/18639	0.244444444444444	1.10053140096618	0.415577379867557	0.855756940623274
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	5/4140	19/18639	0.263157894736842	1.18478260869565	0.418845226103085	0.858365933112533
GO:0008574	plus-end-directed microtubule motor activity	5/4140	19/18639	0.263157894736842	1.18478260869565	0.418845226103085	0.858365933112533
GO:0050145	nucleoside monophosphate kinase activity	5/4140	19/18639	0.263157894736842	1.18478260869565	0.418845226103085	0.858365933112533
GO:0017022	myosin binding	18/4140	76/18639	0.236842105263158	1.06630434782609	0.422372160795243	0.864217759846546
GO:0004559	alpha-mannosidase activity	4/4140	15/18639	0.266666666666667	1.20057971014493	0.435376122718601	0.882407984155653
GO:0004953	icosanoid receptor activity	4/4140	15/18639	0.266666666666667	1.20057971014493	0.435376122718601	0.882407984155653
GO:0008252	nucleotidase activity	4/4140	15/18639	0.266666666666667	1.20057971014493	0.435376122718601	0.882407984155653
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/4140	15/18639	0.266666666666667	1.20057971014493	0.435376122718601	0.882407984155653
GO:0048531	beta-1,3-galactosyltransferase activity	4/4140	15/18639	0.266666666666667	1.20057971014493	0.435376122718601	0.882407984155653
GO:0050780	dopamine receptor binding	4/4140	15/18639	0.266666666666667	1.20057971014493	0.435376122718601	0.882407984155653
GO:0023023	MHC protein complex binding	9/4140	37/18639	0.243243243243243	1.09512338425382	0.441237682876788	0.892881914878029
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	11/4140	46/18639	0.239130434782609	1.07660680529301	0.4471082702247	0.899563596244188
GO:0019957	C-C chemokine binding	6/4140	24/18639	0.25	1.12554347826087	0.448701082660502	0.899563596244188
GO:0050699	WW domain binding	6/4140	24/18639	0.25	1.12554347826087	0.448701082660502	0.899563596244188
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	3/4140	11/18639	0.272727272727273	1.22786561264822	0.455722971834662	0.899563596244188
GO:0003953	NAD+ nucleosidase activity	3/4140	11/18639	0.272727272727273	1.22786561264822	0.455722971834662	0.899563596244188
GO:0004954	prostanoid receptor activity	3/4140	11/18639	0.272727272727273	1.22786561264822	0.455722971834662	0.899563596244188
GO:0005536	D-glucose binding	3/4140	11/18639	0.272727272727273	1.22786561264822	0.455722971834662	0.899563596244188
GO:0010854	adenylate cyclase regulator activity	3/4140	11/18639	0.272727272727273	1.22786561264822	0.455722971834662	0.899563596244188
GO:0015217	ADP transmembrane transporter activity	3/4140	11/18639	0.272727272727273	1.22786561264822	0.455722971834662	0.899563596244188
GO:0019215	intermediate filament binding	3/4140	11/18639	0.272727272727273	1.22786561264822	0.455722971834662	0.899563596244188
GO:0032050	clathrin heavy chain binding	3/4140	11/18639	0.272727272727273	1.22786561264822	0.455722971834662	0.899563596244188
GO:0043522	leucine zipper domain binding	3/4140	11/18639	0.272727272727273	1.22786561264822	0.455722971834662	0.899563596244188
GO:0047676	arachidonate-CoA ligase activity	3/4140	11/18639	0.272727272727273	1.22786561264822	0.455722971834662	0.899563596244188
GO:0180030	inositol phosphate kinase activity	3/4140	11/18639	0.272727272727273	1.22786561264822	0.455722971834662	0.899563596244188
GO:1900750	oligopeptide binding	3/4140	11/18639	0.272727272727273	1.22786561264822	0.455722971834662	0.899563596244188
GO:1990948	ubiquitin ligase inhibitor activity	3/4140	11/18639	0.272727272727273	1.22786561264822	0.455722971834662	0.899563596244188
GO:0004520	DNA endonuclease activity	10/4140	42/18639	0.238095238095238	1.07194616977226	0.460942307492489	0.908472817370342
GO:0016874	ligase activity	38/4140	167/18639	0.227544910179641	1.0244467586566	0.462953883711742	0.911042275744666
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	14/4140	60/18639	0.233333333333333	1.05050724637681	0.467091010401701	0.917780351735862
GO:0016417	S-acyltransferase activity	7/4140	29/18639	0.241379310344828	1.08673163418291	0.47278761727154	0.927557413762914
GO:0140359	ABC-type transporter activity	11/4140	47/18639	0.234042553191489	1.05370027752081	0.478450544667564	0.937238738184407
GO:0019212	phosphatase inhibitor activity	13/4140	56/18639	0.232142857142857	1.04514751552795	0.480160781278062	0.939159461253596
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	4/4140	16/18639	0.25	1.12554347826087	0.489763410424179	0.952153337184167
GO:0005159	insulin-like growth factor receptor binding	4/4140	16/18639	0.25	1.12554347826087	0.489763410424179	0.952153337184167
GO:0015562	efflux transmembrane transporter activity	4/4140	16/18639	0.25	1.12554347826087	0.489763410424179	0.952153337184167
GO:0070411	I-SMAD binding	4/4140	16/18639	0.25	1.12554347826087	0.489763410424179	0.952153337184167
GO:0019706	protein-cysteine S-palmitoyltransferase activity	6/4140	25/18639	0.24	1.08052173913043	0.49191108656199	0.953448145188676
GO:0019707	protein-cysteine S-acyltransferase activity	6/4140	25/18639	0.24	1.08052173913043	0.49191108656199	0.953448145188676
GO:0008200	ion channel inhibitor activity	10/4140	43/18639	0.232558139534884	1.04701718907988	0.493730777082579	0.954876481952496
GO:0015026	coreceptor activity	14/4140	61/18639	0.229508196721311	1.03328581610834	0.494573494433217	0.954876481952496
GO:0035401	histone H3Y41 kinase activity	26/4140	115/18639	0.226086956521739	1.01788279773157	0.495615765302461	0.954876481952496
GO:0140801	histone H2AXY142 kinase activity	26/4140	115/18639	0.226086956521739	1.01788279773157	0.495615765302461	0.954876481952496
GO:0032266	phosphatidylinositol-3-phosphate binding	11/4140	48/18639	0.229166666666667	1.0317481884058	0.509421807834454	0.972938638497416
GO:0015215	nucleotide transmembrane transporter activity	7/4140	30/18639	0.233333333333333	1.05050724637681	0.512067115731708	0.972938638497416
GO:0010314	phosphatidylinositol-5-phosphate binding	5/4140	21/18639	0.238095238095238	1.07194616977226	0.514395234130057	0.972938638497416
GO:1904047	S-adenosyl-L-methionine binding	5/4140	21/18639	0.238095238095238	1.07194616977226	0.514395234130057	0.972938638497416
GO:0003720	telomerase activity	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:0004300	enoyl-CoA hydratase activity	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:0008179	adenylate cyclase binding	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:0008603	cAMP-dependent protein kinase regulator activity	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:0010853	cyclase activator activity	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:0016801	hydrolase activity, acting on ether bonds	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:0016803	ether hydrolase activity	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:0017166	vinculin binding	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:0035251	UDP-glucosyltransferase activity	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:0042301	phosphate ion binding	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:0045295	gamma-catenin binding	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:1990459	transferrin receptor binding	3/4140	12/18639	0.25	1.12554347826087	0.518598217567387	0.972938638497416
GO:0003954	NADH dehydrogenase activity	10/4140	44/18639	0.227272727272727	1.02322134387352	0.525988938304601	0.985367923723466
GO:0005112	Notch binding	6/4140	26/18639	0.230769230769231	1.03896321070234	0.533927905656056	0.994450382893406
GO:0005160	transforming growth factor beta receptor binding	6/4140	26/18639	0.230769230769231	1.03896321070234	0.533927905656056	0.994450382893406
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	6/4140	26/18639	0.230769230769231	1.03896321070234	0.533927905656056	0.994450382893406
GO:0030507	spectrin binding	6/4140	26/18639	0.230769230769231	1.03896321070234	0.533927905656056	0.994450382893406
GO:0005543	phospholipid binding	110/4140	497/18639	0.221327967806841	0.996457002886887	0.535035063458935	0.995072437386776
GO:0004713	protein tyrosine kinase activity	31/4140	140/18639	0.221428571428571	0.996909937888199	0.541061671980892	1
GO:0004550	nucleoside diphosphate kinase activity	4/4140	17/18639	0.235294117647059	1.05933503836317	0.541835241335713	1
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	4/4140	17/18639	0.235294117647059	1.05933503836317	0.541835241335713	1
GO:0017110	nucleoside diphosphate phosphatase activity	4/4140	17/18639	0.235294117647059	1.05933503836317	0.541835241335713	1
GO:0036041	long-chain fatty acid binding	4/4140	17/18639	0.235294117647059	1.05933503836317	0.541835241335713	1
GO:0030971	receptor tyrosine kinase binding	18/4140	81/18639	0.222222222222222	1.00048309178744	0.542615447190746	1
GO:0015485	cholesterol binding	12/4140	54/18639	0.222222222222222	1.00048309178744	0.552449919052123	1
GO:0050660	flavin adenine dinucleotide binding	19/4140	86/18639	0.22093023255814	0.994666329625885	0.55282347151067	1
GO:0042605	peptide antigen binding	10/4140	45/18639	0.222222222222222	1.00048309178744	0.557535097858042	1
GO:0046915	transition metal ion transmembrane transporter activity	10/4140	45/18639	0.222222222222222	1.00048309178744	0.557535097858042	1
GO:0005319	lipid transporter activity	39/4140	178/18639	0.219101123595506	0.9864313629702	0.568168904003943	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	6/4140	27/18639	0.222222222222222	1.00048309178744	0.574394757076433	1
GO:0008137	NADH dehydrogenase (ubiquinone) activity	9/4140	41/18639	0.219512195121951	0.988282078472959	0.576919740466794	1
GO:0003964	RNA-directed DNA polymerase activity	3/4140	13/18639	0.230769230769231	1.03896321070234	0.577291231622287	1
GO:0009982	pseudouridine synthase activity	3/4140	13/18639	0.230769230769231	1.03896321070234	0.577291231622287	1
GO:0031432	titin binding	3/4140	13/18639	0.230769230769231	1.03896321070234	0.577291231622287	1
GO:0043560	insulin receptor substrate binding	3/4140	13/18639	0.230769230769231	1.03896321070234	0.577291231622287	1
GO:0045159	myosin II binding	3/4140	13/18639	0.230769230769231	1.03896321070234	0.577291231622287	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/4140	13/18639	0.230769230769231	1.03896321070234	0.577291231622287	1
GO:0089720	caspase binding	3/4140	13/18639	0.230769230769231	1.03896321070234	0.577291231622287	1
GO:0120015	sterol transfer activity	7/4140	32/18639	0.21875	0.984850543478261	0.587103575674726	1
GO:0035615	clathrin adaptor activity	4/4140	18/18639	0.222222222222222	1.00048309178744	0.591021738197858	1
GO:1990381	ubiquitin-specific protease binding	4/4140	18/18639	0.222222222222222	1.00048309178744	0.591021738197858	1
GO:0005516	calmodulin binding	45/4140	207/18639	0.217391304347826	0.978733459357278	0.592508946434139	1
GO:0016757	glycosyltransferase activity	58/4140	267/18639	0.217228464419476	0.978000325679857	0.600672597421703	1
GO:0005158	insulin receptor binding	5/4140	23/18639	0.217391304347826	0.978733459357278	0.60269876736322	1
GO:0016493	C-C chemokine receptor activity	5/4140	23/18639	0.217391304347826	0.978733459357278	0.60269876736322	1
GO:0016866	intramolecular transferase activity	6/4140	28/18639	0.214285714285714	0.964751552795031	0.613027542916786	1
GO:0046875	ephrin receptor binding	6/4140	28/18639	0.214285714285714	0.964751552795031	0.613027542916786	1
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	6/4140	28/18639	0.214285714285714	0.964751552795031	0.613027542916786	1
GO:0042626	ATPase-coupled transmembrane transporter activity	21/4140	98/18639	0.214285714285714	0.964751552795031	0.61334672486541	1
GO:0005347	ATP transmembrane transporter activity	3/4140	14/18639	0.214285714285714	0.964751552795031	0.631249237773701	1
GO:0008559	ABC-type xenobiotic transporter activity	3/4140	14/18639	0.214285714285714	0.964751552795031	0.631249237773701	1
GO:0016530	metallochaperone activity	3/4140	14/18639	0.214285714285714	0.964751552795031	0.631249237773701	1
GO:0019992	diacylglycerol binding	3/4140	14/18639	0.214285714285714	0.964751552795031	0.631249237773701	1
GO:0032036	myosin heavy chain binding	3/4140	14/18639	0.214285714285714	0.964751552795031	0.631249237773701	1
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	3/4140	14/18639	0.214285714285714	0.964751552795031	0.631249237773701	1
GO:0044325	transmembrane transporter binding	29/4140	136/18639	0.213235294117647	0.960022378516624	0.631808055237351	1
GO:0140299	molecular sensor activity	15/4140	71/18639	0.211267605633803	0.951163502755664	0.632953654077108	1
GO:0003756	protein disulfide isomerase activity	4/4140	19/18639	0.210526315789474	0.947826086956522	0.636935474756464	1
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	4/4140	19/18639	0.210526315789474	0.947826086956522	0.636935474756464	1
GO:0031420	alkali metal ion binding	4/4140	19/18639	0.210526315789474	0.947826086956522	0.636935474756464	1
GO:0042577	lipid phosphatase activity	4/4140	19/18639	0.210526315789474	0.947826086956522	0.636935474756464	1
GO:0015295	solute:proton symporter activity	5/4140	24/18639	0.208333333333333	0.937952898550725	0.643224473863935	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	5/4140	24/18639	0.208333333333333	0.937952898550725	0.643224473863935	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	5/4140	24/18639	0.208333333333333	0.937952898550725	0.643224473863935	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	5/4140	24/18639	0.208333333333333	0.937952898550725	0.643224473863935	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	10/4140	48/18639	0.208333333333333	0.937952898550725	0.646413700150871	1
GO:0001618	virus receptor activity	17/4140	81/18639	0.209876543209877	0.944900697799248	0.647323208466047	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/4140	29/18639	0.206896551724138	0.931484257871064	0.64961187134598	1
GO:0004864	protein phosphatase inhibitor activity	11/4140	53/18639	0.207547169811321	0.934413453650533	0.653453128522203	1
GO:0005246	calcium channel regulator activity	11/4140	53/18639	0.207547169811321	0.934413453650533	0.653453128522203	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	18/4140	86/18639	0.209302325581395	0.942315470171891	0.653988896923912	1
GO:0016831	carboxy-lyase activity	7/4140	34/18639	0.205882352941176	0.926918158567775	0.655909737062988	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	7/4140	34/18639	0.205882352941176	0.926918158567775	0.655909737062988	1
GO:0015399	primary active transmembrane transporter activity	35/4140	166/18639	0.210843373493976	0.949253535882661	0.666659492870336	1
GO:0140272	exogenous protein binding	17/4140	82/18639	0.207317073170732	0.933377518557794	0.668624211623013	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	14/4140	68/18639	0.205882352941176	0.926918158567775	0.672512176178448	1
GO:0032934	sterol binding	14/4140	68/18639	0.205882352941176	0.926918158567775	0.672512176178448	1
GO:0008081	phosphoric diester hydrolase activity	18/4140	87/18639	0.206896551724138	0.931484257871064	0.67451647953643	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	11/4140	54/18639	0.203703703703704	0.917109500805153	0.679291158851758	1
GO:0015095	magnesium ion transmembrane transporter activity	4/4140	20/18639	0.2	0.900434782608696	0.679347117633686	1
GO:0043178	alcohol binding	19/4140	92/18639	0.206521739130435	0.929796786389414	0.68017195739093	1
GO:0004467	long-chain fatty acid-CoA ligase activity	3/4140	15/18639	0.2	0.900434782608696	0.680217516537476	1
GO:0005523	tropomyosin binding	3/4140	15/18639	0.2	0.900434782608696	0.680217516537476	1
GO:0016846	carbon-sulfur lyase activity	3/4140	15/18639	0.2	0.900434782608696	0.680217516537476	1
GO:0015662	P-type ion transporter activity	5/4140	25/18639	0.2	0.900434782608696	0.681052820689422	1
GO:0120020	cholesterol transfer activity	5/4140	25/18639	0.2	0.900434782608696	0.681052820689422	1
GO:0140358	P-type transmembrane transporter activity	5/4140	25/18639	0.2	0.900434782608696	0.681052820689422	1
GO:1902936	phosphatidylinositol bisphosphate binding	23/4140	111/18639	0.207207207207207	0.932882882882883	0.683364128533007	1
GO:0051015	actin filament binding	44/4140	209/18639	0.210526315789474	0.947826086956522	0.683398523338888	1
GO:0001965	G-protein alpha-subunit binding	6/4140	30/18639	0.2	0.900434782608696	0.683998060249548	1
GO:0031210	phosphatidylcholine binding	6/4140	30/18639	0.2	0.900434782608696	0.683998060249548	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0004090	carbonyl reductase (NADPH) activity	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0004382	GDP phosphatase activity	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0004935	adrenergic receptor activity	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0015187	glycine transmembrane transporter activity	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0015279	store-operated calcium channel activity	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0015643	toxic substance binding	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0031434	mitogen-activated protein kinase kinase binding	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0035256	G protein-coupled glutamate receptor binding	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0047429	nucleoside triphosphate diphosphatase activity	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0050308	sugar-phosphatase activity	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0070513	death domain binding	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0141109	transporter activator activity	2/4140	10/18639	0.2	0.900434782608696	0.687305218365326	1
GO:0071949	FAD binding	8/4140	40/18639	0.2	0.900434782608696	0.691507459672666	1
GO:0015605	organophosphate ester transmembrane transporter activity	10/4140	50/18639	0.2	0.900434782608696	0.699771134704757	1
GO:0008374	O-acyltransferase activity	11/4140	55/18639	0.2	0.900434782608696	0.70395643948861	1
GO:0046982	protein heterodimerization activity	78/4140	369/18639	0.211382113821138	0.951679038529516	0.711043352584255	1
GO:0001637	G protein-coupled chemoattractant receptor activity	5/4140	26/18639	0.192307692307692	0.865802675585284	0.716082562364033	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	5/4140	26/18639	0.192307692307692	0.865802675585284	0.716082562364033	1
GO:0004950	chemokine receptor activity	5/4140	26/18639	0.192307692307692	0.865802675585284	0.716082562364033	1
GO:0050750	low-density lipoprotein particle receptor binding	5/4140	26/18639	0.192307692307692	0.865802675585284	0.716082562364033	1
GO:0016878	acid-thiol ligase activity	6/4140	31/18639	0.193548387096774	0.871388499298738	0.716094793080703	1
GO:0045505	dynein intermediate chain binding	7/4140	36/18639	0.194444444444444	0.87542270531401	0.717319036650095	1
GO:0009975	cyclase activity	4/4140	21/18639	0.19047619047619	0.857556935817805	0.718159325516893	1
GO:0140312	cargo adaptor activity	4/4140	21/18639	0.19047619047619	0.857556935817805	0.718159325516893	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	8/4140	41/18639	0.195121951219512	0.87847295864263	0.719286300692271	1
GO:0022853	active monoatomic ion transmembrane transporter activity	24/4140	118/18639	0.203389830508475	0.915696389093589	0.721936420013914	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/4140	16/18639	0.1875	0.844157608695652	0.724168464102083	1
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/4140	16/18639	0.1875	0.844157608695652	0.724168464102083	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/4140	16/18639	0.1875	0.844157608695652	0.724168464102083	1
GO:0002162	dystroglycan binding	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0004016	adenylate cyclase activity	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0005114	type II transforming growth factor beta receptor binding	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0005225	volume-sensitive anion channel activity	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0008172	S-methyltransferase activity	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0008432	JUN kinase binding	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0019203	carbohydrate phosphatase activity	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0034056	estrogen response element binding	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0045294	alpha-catenin binding	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0050786	RAGE receptor binding	2/4140	11/18639	0.181818181818182	0.818577075098814	0.738767939816584	1
GO:0019894	kinesin binding	8/4140	42/18639	0.19047619047619	0.857556935817805	0.745341912746973	1
GO:0016405	CoA-ligase activity	5/4140	27/18639	0.185185185185185	0.833735909822866	0.748284336293033	1
GO:0003774	cytoskeletal motor activity	31/4140	153/18639	0.202614379084967	0.912205171923842	0.748738418852229	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	11/4140	57/18639	0.192982456140351	0.868840579710145	0.749608244694176	1
GO:0008093	cytoskeletal anchor activity	4/4140	22/18639	0.181818181818182	0.818577075098814	0.753381053253064	1
GO:0031683	G-protein beta/gamma-subunit complex binding	4/4140	22/18639	0.181818181818182	0.818577075098814	0.753381053253064	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/4140	17/18639	0.176470588235294	0.794501278772379	0.763239868980591	1
GO:0015278	intracellularly gated calcium channel activity	3/4140	17/18639	0.176470588235294	0.794501278772379	0.763239868980591	1
GO:0016018	cyclosporin A binding	3/4140	17/18639	0.176470588235294	0.794501278772379	0.763239868980591	1
GO:0019198	transmembrane receptor protein phosphatase activity	3/4140	17/18639	0.176470588235294	0.794501278772379	0.763239868980591	1
GO:0032977	membrane insertase activity	3/4140	17/18639	0.176470588235294	0.794501278772379	0.763239868980591	1
GO:0046965	nuclear retinoid X receptor binding	3/4140	17/18639	0.176470588235294	0.794501278772379	0.763239868980591	1
GO:0048038	quinone binding	3/4140	17/18639	0.176470588235294	0.794501278772379	0.763239868980591	1
GO:0070402	NADPH binding	3/4140	17/18639	0.176470588235294	0.794501278772379	0.763239868980591	1
GO:0009055	electron transfer activity	23/4140	116/18639	0.198275862068966	0.892672413793103	0.764809500687389	1
GO:0042887	amide transmembrane transporter activity	7/4140	38/18639	0.184210526315789	0.829347826086957	0.77084010018655	1
GO:0030296	protein tyrosine kinase activator activity	6/4140	33/18639	0.181818181818182	0.818577075098814	0.773303409627415	1
GO:0030165	PDZ domain binding	16/4140	83/18639	0.192771084337349	0.867888947092719	0.778455404416548	1
GO:0005165	neurotrophin receptor binding	2/4140	12/18639	0.166666666666667	0.75036231884058	0.782801884266424	1
GO:0005436	sodium:phosphate symporter activity	2/4140	12/18639	0.166666666666667	0.75036231884058	0.782801884266424	1
GO:0015166	polyol transmembrane transporter activity	2/4140	12/18639	0.166666666666667	0.75036231884058	0.782801884266424	1
GO:0016840	carbon-nitrogen lyase activity	2/4140	12/18639	0.166666666666667	0.75036231884058	0.782801884266424	1
GO:0031543	peptidyl-proline dioxygenase activity	2/4140	12/18639	0.166666666666667	0.75036231884058	0.782801884266424	1
GO:0035259	nuclear glucocorticoid receptor binding	2/4140	12/18639	0.166666666666667	0.75036231884058	0.782801884266424	1
GO:0035497	cAMP response element binding	2/4140	12/18639	0.166666666666667	0.75036231884058	0.782801884266424	1
GO:0070008	serine-type exopeptidase activity	2/4140	12/18639	0.166666666666667	0.75036231884058	0.782801884266424	1
GO:0016849	phosphorus-oxygen lyase activity	4/4140	23/18639	0.173913043478261	0.782986767485822	0.785103639756189	1
GO:0031681	G-protein beta-subunit binding	4/4140	23/18639	0.173913043478261	0.782986767485822	0.785103639756189	1
GO:0050661	NADP binding	10/4140	54/18639	0.185185185185185	0.833735909822866	0.79028492171759	1
GO:0004857	enzyme inhibitor activity	86/4140	416/18639	0.206730769230769	0.930737876254181	0.793799671647573	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	7/4140	39/18639	0.179487179487179	0.808082497212932	0.794639179465069	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/4140	18/18639	0.166666666666667	0.75036231884058	0.797683495137137	1
GO:0015172	acidic amino acid transmembrane transporter activity	3/4140	18/18639	0.166666666666667	0.75036231884058	0.797683495137137	1
GO:0017075	syntaxin-1 binding	3/4140	18/18639	0.166666666666667	0.75036231884058	0.797683495137137	1
GO:1901611	phosphatidylglycerol binding	3/4140	18/18639	0.166666666666667	0.75036231884058	0.797683495137137	1
GO:0008376	acetylgalactosaminyltransferase activity	6/4140	34/18639	0.176470588235294	0.794501278772379	0.798459196605507	1
GO:0051427	hormone receptor binding	6/4140	34/18639	0.176470588235294	0.794501278772379	0.798459196605507	1
GO:0003785	actin monomer binding	5/4140	29/18639	0.172413793103448	0.77623688155922	0.804370511127213	1
GO:0098531	ligand-modulated transcription factor activity	11/4140	60/18639	0.183333333333333	0.825398550724638	0.808669678091811	1
GO:0005315	phosphate transmembrane transporter activity	4/4140	24/18639	0.166666666666667	0.75036231884058	0.81347947293464	1
GO:0050997	quaternary ammonium group binding	7/4140	40/18639	0.175	0.787880434782609	0.816515604875578	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/4140	13/18639	0.153846153846154	0.692642140468227	0.820167457474448	1
GO:0008417	fucosyltransferase activity	2/4140	13/18639	0.153846153846154	0.692642140468227	0.820167457474448	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/4140	13/18639	0.153846153846154	0.692642140468227	0.820167457474448	1
GO:0030955	potassium ion binding	2/4140	13/18639	0.153846153846154	0.692642140468227	0.820167457474448	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/4140	13/18639	0.153846153846154	0.692642140468227	0.820167457474448	1
GO:0008235	metalloexopeptidase activity	12/4140	66/18639	0.181818181818182	0.818577075098814	0.824970391529598	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	3/4140	19/18639	0.157894736842105	0.710869565217391	0.827823748958514	1
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/4140	19/18639	0.157894736842105	0.710869565217391	0.827823748958514	1
GO:0008381	mechanosensitive monoatomic ion channel activity	3/4140	19/18639	0.157894736842105	0.710869565217391	0.827823748958514	1
GO:0015245	fatty acid transmembrane transporter activity	3/4140	19/18639	0.157894736842105	0.710869565217391	0.827823748958514	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/4140	19/18639	0.157894736842105	0.710869565217391	0.827823748958514	1
GO:0046527	glucosyltransferase activity	3/4140	19/18639	0.157894736842105	0.710869565217391	0.827823748958514	1
GO:0070003	threonine-type peptidase activity	3/4140	19/18639	0.157894736842105	0.710869565217391	0.827823748958514	1
GO:0003707	nuclear steroid receptor activity	4/4140	25/18639	0.16	0.720347826086957	0.838703597171824	1
GO:0008483	transaminase activity	4/4140	25/18639	0.16	0.720347826086957	0.838703597171824	1
GO:0015645	fatty acid ligase activity	4/4140	25/18639	0.16	0.720347826086957	0.838703597171824	1
GO:0120515	fatty acid-CoA ligase activity	4/4140	25/18639	0.16	0.720347826086957	0.838703597171824	1
GO:0008238	exopeptidase activity	19/4140	102/18639	0.186274509803922	0.838640238704177	0.839629127646179	1
GO:0005200	structural constituent of cytoskeleton	21/4140	112/18639	0.1875	0.844157608695652	0.840975344626345	1
GO:0004190	aspartic-type endopeptidase activity	6/4140	36/18639	0.166666666666667	0.75036231884058	0.842214866234018	1
GO:0016829	lyase activity	39/4140	200/18639	0.195	0.877923913043478	0.84466352762244	1
GO:0070325	lipoprotein particle receptor binding	5/4140	31/18639	0.161290322580645	0.726157082748948	0.850050810576216	1
GO:0072349	modified amino acid transmembrane transporter activity	5/4140	31/18639	0.161290322580645	0.726157082748948	0.850050810576216	1
GO:0005504	fatty acid binding	8/4140	47/18639	0.170212765957447	0.766327474560592	0.850059511647508	1
GO:0005161	platelet-derived growth factor receptor binding	2/4140	14/18639	0.142857142857143	0.643167701863354	0.851653827424573	1
GO:0008195	phosphatidate phosphatase activity	2/4140	14/18639	0.142857142857143	0.643167701863354	0.851653827424573	1
GO:0008494	translation activator activity	2/4140	14/18639	0.142857142857143	0.643167701863354	0.851653827424573	1
GO:0015386	potassium:proton antiporter activity	2/4140	14/18639	0.142857142857143	0.643167701863354	0.851653827424573	1
GO:0015926	glucosidase activity	2/4140	14/18639	0.142857142857143	0.643167701863354	0.851653827424573	1
GO:0031404	chloride ion binding	2/4140	14/18639	0.142857142857143	0.643167701863354	0.851653827424573	1
GO:1901612	cardiolipin binding	2/4140	14/18639	0.142857142857143	0.643167701863354	0.851653827424573	1
GO:0001614	purinergic nucleotide receptor activity	3/4140	20/18639	0.15	0.675326086956522	0.854025507427601	1
GO:0010851	cyclase regulator activity	3/4140	20/18639	0.15	0.675326086956522	0.854025507427601	1
GO:0016502	nucleotide receptor activity	3/4140	20/18639	0.15	0.675326086956522	0.854025507427601	1
GO:0031418	L-ascorbic acid binding	3/4140	20/18639	0.15	0.675326086956522	0.854025507427601	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	10/4140	58/18639	0.172413793103448	0.77623688155922	0.859109646904506	1
GO:0008198	ferrous iron binding	4/4140	26/18639	0.153846153846154	0.692642140468227	0.86099833077324	1
GO:0015216	purine nucleotide transmembrane transporter activity	4/4140	26/18639	0.153846153846154	0.692642140468227	0.86099833077324	1
GO:0030247	polysaccharide binding	4/4140	26/18639	0.153846153846154	0.692642140468227	0.86099833077324	1
GO:0051139	metal cation:proton antiporter activity	4/4140	26/18639	0.153846153846154	0.692642140468227	0.86099833077324	1
GO:0070001	aspartic-type peptidase activity	6/4140	37/18639	0.162162162162162	0.730082256169213	0.861016388967081	1
GO:1901505	carbohydrate derivative transmembrane transporter activity	9/4140	53/18639	0.169811320754717	0.764520098441345	0.862207908808222	1
GO:0016835	carbon-oxygen lyase activity	14/4140	79/18639	0.177215189873418	0.797853604843148	0.865308936548508	1
GO:0043425	bHLH transcription factor binding	5/4140	32/18639	0.15625	0.703464673913043	0.869345035294502	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	7/4140	43/18639	0.162790697674419	0.732912032355915	0.871320886130016	1
GO:0008237	metallopeptidase activity	35/4140	184/18639	0.190217391304348	0.856391776937618	0.873007980025795	1
GO:0001786	phosphatidylserine binding	10/4140	59/18639	0.169491525423729	0.763080324244657	0.873165509229814	1
GO:0004879	nuclear receptor activity	10/4140	59/18639	0.169491525423729	0.763080324244657	0.873165509229814	1
GO:0070888	E-box binding	10/4140	59/18639	0.169491525423729	0.763080324244657	0.873165509229814	1
GO:0008194	UDP-glycosyltransferase activity	27/4140	145/18639	0.186206896551724	0.838335832083958	0.875209956948477	1
GO:0019200	carbohydrate kinase activity	3/4140	21/18639	0.142857142857143	0.643167701863354	0.876669871079386	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/4140	15/18639	0.133333333333333	0.600289855072464	0.878028644484126	1
GO:0015929	hexosaminidase activity	2/4140	15/18639	0.133333333333333	0.600289855072464	0.878028644484126	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/4140	15/18639	0.133333333333333	0.600289855072464	0.878028644484126	1
GO:0017081	chloride channel regulator activity	2/4140	15/18639	0.133333333333333	0.600289855072464	0.878028644484126	1
GO:0033130	acetylcholine receptor binding	2/4140	15/18639	0.133333333333333	0.600289855072464	0.878028644484126	1
GO:0047372	monoacylglycerol lipase activity	2/4140	15/18639	0.133333333333333	0.600289855072464	0.878028644484126	1
GO:0023026	MHC class II protein complex binding	4/4140	27/18639	0.148148148148148	0.666988727858293	0.880600764595885	1
GO:0008013	beta-catenin binding	19/4140	106/18639	0.179245283018868	0.806993437243642	0.883445285368915	1
GO:0004896	cytokine receptor activity	17/4140	96/18639	0.177083333333333	0.797259963768116	0.884661855947196	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	5/4140	33/18639	0.151515151515152	0.682147562582345	0.886495325592197	1
GO:0008970	phospholipase A1 activity	3/4140	22/18639	0.136363636363636	0.613932806324111	0.896136526525647	1
GO:0016881	acid-amino acid ligase activity	3/4140	22/18639	0.136363636363636	0.613932806324111	0.896136526525647	1
GO:0005126	cytokine receptor binding	53/4140	275/18639	0.192727272727273	0.867691699604743	0.896647224341665	1
GO:0046625	sphingolipid binding	4/4140	28/18639	0.142857142857143	0.643167701863354	0.897752894190699	1
GO:0051119	sugar transmembrane transporter activity	4/4140	28/18639	0.142857142857143	0.643167701863354	0.897752894190699	1
GO:0005149	interleukin-1 receptor binding	2/4140	16/18639	0.125	0.562771739130435	0.90000867025299	1
GO:0008142	oxysterol binding	2/4140	16/18639	0.125	0.562771739130435	0.90000867025299	1
GO:0015385	sodium:proton antiporter activity	2/4140	16/18639	0.125	0.562771739130435	0.90000867025299	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/4140	16/18639	0.125	0.562771739130435	0.90000867025299	1
GO:0030170	pyridoxal phosphate binding	9/4140	56/18639	0.160714285714286	0.723563664596273	0.901677420425719	1
GO:0016830	carbon-carbon lyase activity	8/4140	51/18639	0.156862745098039	0.706223358908781	0.906276576373228	1
GO:0015144	carbohydrate transmembrane transporter activity	6/4140	40/18639	0.15	0.675326086956522	0.906576326577515	1
GO:0015179	L-amino acid transmembrane transporter activity	10/4140	62/18639	0.161290322580645	0.726157082748948	0.90863371335423	1
GO:0070279	vitamin B6 binding	9/4140	57/18639	0.157894736842105	0.710869565217391	0.912521724281865	1
GO:0005416	amino acid:monoatomic cation symporter activity	4/4140	29/18639	0.137931034482759	0.620989505247376	0.912694075480857	1
GO:0000295	adenine nucleotide transmembrane transporter activity	3/4140	23/18639	0.130434782608696	0.587240075614367	0.912791459541066	1
GO:0005283	amino acid:sodium symporter activity	3/4140	23/18639	0.130434782608696	0.587240075614367	0.912791459541066	1
GO:0017134	fibroblast growth factor binding	3/4140	23/18639	0.130434782608696	0.587240075614367	0.912791459541066	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/4140	23/18639	0.130434782608696	0.587240075614367	0.912791459541066	1
GO:0003779	actin binding	87/4140	443/18639	0.196388261851016	0.884174109333595	0.917160638720412	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/4140	17/18639	0.117647058823529	0.529667519181586	0.918244510422643	1
GO:0016805	dipeptidase activity	2/4140	17/18639	0.117647058823529	0.529667519181586	0.918244510422643	1
GO:0038191	neuropilin binding	2/4140	17/18639	0.117647058823529	0.529667519181586	0.918244510422643	1
GO:0004175	endopeptidase activity	79/4140	405/18639	0.195061728395062	0.878201825013419	0.918555470949026	1
GO:0001530	lipopolysaccharide binding	6/4140	41/18639	0.146341463414634	0.658854718981972	0.918583684940117	1
GO:0004812	aminoacyl-tRNA ligase activity	6/4140	41/18639	0.146341463414634	0.658854718981972	0.918583684940117	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	6/4140	41/18639	0.146341463414634	0.658854718981972	0.918583684940117	1
GO:0000182	rDNA binding	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0005345	purine nucleobase transmembrane transporter activity	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0008190	eukaryotic initiation factor 4E binding	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0008519	ammonium channel activity	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0019911	structural constituent of myelin sheath	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0031419	cobalamin binding	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0035374	chondroitin sulfate binding	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0043208	glycosphingolipid binding	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0070097	delta-catenin binding	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0070739	protein-glutamic acid ligase activity	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0070740	tubulin-glutamic acid ligase activity	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:1990763	arrestin family protein binding	1/4140	10/18639	0.1	0.450217391304348	0.918930982539159	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	4/4140	30/18639	0.133333333333333	0.600289855072464	0.925655471508258	1
GO:0016769	transferase activity, transferring nitrogenous groups	4/4140	30/18639	0.133333333333333	0.600289855072464	0.925655471508258	1
GO:0004033	aldo-keto reductase (NADPH) activity	5/4140	36/18639	0.138888888888889	0.62530193236715	0.926801257383518	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/4140	24/18639	0.125	0.562771739130435	0.926978886199127	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	3/4140	24/18639	0.125	0.562771739130435	0.926978886199127	1
GO:0015149	hexose transmembrane transporter activity	3/4140	24/18639	0.125	0.562771739130435	0.926978886199127	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/4140	24/18639	0.125	0.562771739130435	0.926978886199127	1
GO:0030215	semaphorin receptor binding	3/4140	24/18639	0.125	0.562771739130435	0.926978886199127	1
GO:0030552	cAMP binding	3/4140	24/18639	0.125	0.562771739130435	0.926978886199127	1
GO:0055056	D-glucose transmembrane transporter activity	3/4140	24/18639	0.125	0.562771739130435	0.926978886199127	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	15/4140	91/18639	0.164835164835165	0.742116579073101	0.929864667123186	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/4140	18/18639	0.111111111111111	0.50024154589372	0.933314637333331	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/4140	18/18639	0.111111111111111	0.50024154589372	0.933314637333331	1
GO:0032393	MHC class I receptor activity	2/4140	18/18639	0.111111111111111	0.50024154589372	0.933314637333331	1
GO:0070064	proline-rich region binding	2/4140	18/18639	0.111111111111111	0.50024154589372	0.933314637333331	1
GO:0098641	cadherin binding involved in cell-cell adhesion	2/4140	18/18639	0.111111111111111	0.50024154589372	0.933314637333331	1
GO:0052689	carboxylic ester hydrolase activity	15/4140	92/18639	0.16304347826087	0.734050094517958	0.936573964601124	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/4140	31/18639	0.129032258064516	0.580925666199159	0.936856162016709	1
GO:0008271	secondary active sulfate transmembrane transporter activity	1/4140	11/18639	0.0909090909090909	0.409288537549407	0.936947286811416	1
GO:0015205	nucleobase transmembrane transporter activity	1/4140	11/18639	0.0909090909090909	0.409288537549407	0.936947286811416	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/4140	11/18639	0.0909090909090909	0.409288537549407	0.936947286811416	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/4140	11/18639	0.0909090909090909	0.409288537549407	0.936947286811416	1
GO:0035252	UDP-xylosyltransferase activity	1/4140	11/18639	0.0909090909090909	0.409288537549407	0.936947286811416	1
GO:0042285	xylosyltransferase activity	1/4140	11/18639	0.0909090909090909	0.409288537549407	0.936947286811416	1
GO:0048185	activin binding	1/4140	11/18639	0.0909090909090909	0.409288537549407	0.936947286811416	1
GO:0070697	activin receptor binding	1/4140	11/18639	0.0909090909090909	0.409288537549407	0.936947286811416	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/4140	11/18639	0.0909090909090909	0.409288537549407	0.936947286811416	1
GO:0022829	wide pore channel activity	5/4140	37/18639	0.135135135135135	0.608401880141011	0.937080143073586	1
GO:0070851	growth factor receptor binding	24/4140	139/18639	0.172661870503597	0.777353769158586	0.938025332977241	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/4140	25/18639	0.12	0.540260869565217	0.939016425611941	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	22/4140	130/18639	0.169230769230769	0.76190635451505	0.944583230279138	1
GO:0022821	solute:potassium antiporter activity	2/4140	19/18639	0.105263157894737	0.473913043478261	0.94572533008331	1
GO:0097001	ceramide binding	2/4140	19/18639	0.105263157894737	0.473913043478261	0.94572533008331	1
GO:0016836	hydro-lyase activity	9/4140	61/18639	0.147540983606557	0.664255167498218	0.946288129123557	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/4140	32/18639	0.125	0.562771739130435	0.94650060869131	1
GO:0016758	hexosyltransferase activity	35/4140	197/18639	0.177664974619289	0.799878613992496	0.947674354993671	1
GO:0048020	CCR chemokine receptor binding	7/4140	50/18639	0.14	0.630304347826087	0.948445020871473	1
GO:0004222	metalloendopeptidase activity	18/4140	110/18639	0.163636363636364	0.736719367588933	0.948876912690886	1
GO:0015145	monosaccharide transmembrane transporter activity	3/4140	26/18639	0.115384615384615	0.519481605351171	0.949192698851772	1
GO:0004859	phospholipase inhibitor activity	1/4140	12/18639	0.0833333333333333	0.37518115942029	0.950960505224597	1
GO:0005025	transforming growth factor beta receptor activity, type I	1/4140	12/18639	0.0833333333333333	0.37518115942029	0.950960505224597	1
GO:0005026	transforming growth factor beta receptor activity, type II	1/4140	12/18639	0.0833333333333333	0.37518115942029	0.950960505224597	1
GO:0005247	voltage-gated chloride channel activity	1/4140	12/18639	0.0833333333333333	0.37518115942029	0.950960505224597	1
GO:0015269	calcium-activated potassium channel activity	1/4140	12/18639	0.0833333333333333	0.37518115942029	0.950960505224597	1
GO:0015368	calcium:monoatomic cation antiporter activity	1/4140	12/18639	0.0833333333333333	0.37518115942029	0.950960505224597	1
GO:0016208	AMP binding	1/4140	12/18639	0.0833333333333333	0.37518115942029	0.950960505224597	1
GO:0016361	activin receptor activity, type I	1/4140	12/18639	0.0833333333333333	0.37518115942029	0.950960505224597	1
GO:0016362	activin receptor activity, type II	1/4140	12/18639	0.0833333333333333	0.37518115942029	0.950960505224597	1
GO:0017002	activin receptor activity	1/4140	12/18639	0.0833333333333333	0.37518115942029	0.950960505224597	1
GO:0070410	co-SMAD binding	1/4140	12/18639	0.0833333333333333	0.37518115942029	0.950960505224597	1
GO:0097371	MDM2/MDM4 family protein binding	1/4140	12/18639	0.0833333333333333	0.37518115942029	0.950960505224597	1
GO:0042277	peptide binding	45/4140	249/18639	0.180722891566265	0.813645887899424	0.954109483018148	1
GO:0016597	amino acid binding	7/4140	51/18639	0.137254901960784	0.617945439045183	0.955153637041648	1
GO:0001972	retinoic acid binding	2/4140	20/18639	0.1	0.450217391304348	0.955914199267277	1
GO:0004364	glutathione transferase activity	3/4140	27/18639	0.111111111111111	0.50024154589372	0.957766690633757	1
GO:0005385	zinc ion transmembrane transporter activity	3/4140	27/18639	0.111111111111111	0.50024154589372	0.957766690633757	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	3/4140	27/18639	0.111111111111111	0.50024154589372	0.957766690633757	1
GO:0005507	copper ion binding	9/4140	63/18639	0.142857142857143	0.643167701863354	0.958391176207707	1
GO:0048306	calcium-dependent protein binding	12/4140	80/18639	0.15	0.675326086956522	0.95973747005576	1
GO:0019955	cytokine binding	24/4140	144/18639	0.166666666666667	0.75036231884058	0.959869292447687	1
GO:0072341	modified amino acid binding	14/4140	91/18639	0.153846153846154	0.692642140468227	0.960025609833025	1
GO:0004180	carboxypeptidase activity	6/4140	46/18639	0.130434782608696	0.587240075614367	0.960461949524746	1
GO:0090482	vitamin transmembrane transporter activity	4/4140	34/18639	0.117647058823529	0.529667519181586	0.961857630255957	1
GO:0002161	aminoacyl-tRNA editing activity	1/4140	13/18639	0.0769230769230769	0.346321070234114	0.961859925870443	1
GO:0005172	vascular endothelial growth factor receptor binding	1/4140	13/18639	0.0769230769230769	0.346321070234114	0.961859925870443	1
GO:0005542	folic acid binding	1/4140	13/18639	0.0769230769230769	0.346321070234114	0.961859925870443	1
GO:0008035	high-density lipoprotein particle binding	1/4140	13/18639	0.0769230769230769	0.346321070234114	0.961859925870443	1
GO:0017154	semaphorin receptor activity	1/4140	13/18639	0.0769230769230769	0.346321070234114	0.961859925870443	1
GO:0061459	L-arginine transmembrane transporter activity	1/4140	13/18639	0.0769230769230769	0.346321070234114	0.961859925870443	1
GO:0070123	transforming growth factor beta receptor activity, type III	1/4140	13/18639	0.0769230769230769	0.346321070234114	0.961859925870443	1
GO:0070700	BMP receptor binding	1/4140	13/18639	0.0769230769230769	0.346321070234114	0.961859925870443	1
GO:0071837	HMG box domain binding	1/4140	13/18639	0.0769230769230769	0.346321070234114	0.961859925870443	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/4140	13/18639	0.0769230769230769	0.346321070234114	0.961859925870443	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/4140	13/18639	0.0769230769230769	0.346321070234114	0.961859925870443	1
GO:1901338	catecholamine binding	1/4140	13/18639	0.0769230769230769	0.346321070234114	0.961859925870443	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	92/4140	484/18639	0.190082644628099	0.855785123966942	0.963756035745018	1
GO:0001846	opsonin binding	2/4140	21/18639	0.0952380952380952	0.428778467908903	0.964255707497582	1
GO:0008373	sialyltransferase activity	2/4140	21/18639	0.0952380952380952	0.428778467908903	0.964255707497582	1
GO:0015174	basic amino acid transmembrane transporter activity	2/4140	21/18639	0.0952380952380952	0.428778467908903	0.964255707497582	1
GO:0051428	peptide hormone receptor binding	2/4140	21/18639	0.0952380952380952	0.428778467908903	0.964255707497582	1
GO:0061891	calcium ion sensor activity	2/4140	21/18639	0.0952380952380952	0.428778467908903	0.964255707497582	1
GO:0045499	chemorepellent activity	3/4140	28/18639	0.107142857142857	0.482375776397515	0.964968346206925	1
GO:0005544	calcium-dependent phospholipid binding	7/4140	53/18639	0.132075471698113	0.594626743232157	0.966263773020427	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	8/4140	59/18639	0.135593220338983	0.610464259395726	0.966983654456118	1
GO:0016229	steroid dehydrogenase activity	4/4140	35/18639	0.114285714285714	0.514534161490683	0.967896918353288	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	13/4140	88/18639	0.147727272727273	0.665093873517787	0.969876353036124	1
GO:0005313	L-glutamate transmembrane transporter activity	1/4140	14/18639	0.0714285714285714	0.321583850931677	0.970337318058587	1
GO:0005344	oxygen carrier activity	1/4140	14/18639	0.0714285714285714	0.321583850931677	0.970337318058587	1
GO:0008191	metalloendopeptidase inhibitor activity	1/4140	14/18639	0.0714285714285714	0.321583850931677	0.970337318058587	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/4140	14/18639	0.0714285714285714	0.321583850931677	0.970337318058587	1
GO:0019763	immunoglobulin receptor activity	1/4140	14/18639	0.0714285714285714	0.321583850931677	0.970337318058587	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/4140	14/18639	0.0714285714285714	0.321583850931677	0.970337318058587	1
GO:0042813	Wnt receptor activity	1/4140	14/18639	0.0714285714285714	0.321583850931677	0.970337318058587	1
GO:0043176	amine binding	1/4140	14/18639	0.0714285714285714	0.321583850931677	0.970337318058587	1
GO:0098821	BMP receptor activity	1/4140	14/18639	0.0714285714285714	0.321583850931677	0.970337318058587	1
GO:1901474	azole transmembrane transporter activity	1/4140	14/18639	0.0714285714285714	0.321583850931677	0.970337318058587	1
GO:0038187	pattern recognition receptor activity	6/4140	48/18639	0.125	0.562771739130435	0.97081103926059	1
GO:0099604	ligand-gated calcium channel activity	3/4140	29/18639	0.103448275862069	0.465742128935532	0.970999992829163	1
GO:0033691	sialic acid binding	2/4140	22/18639	0.0909090909090909	0.409288537549407	0.971067625594775	1
GO:0140784	metal ion sensor activity	2/4140	22/18639	0.0909090909090909	0.409288537549407	0.971067625594775	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	21/4140	132/18639	0.159090909090909	0.716254940711462	0.971905972993642	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/4140	36/18639	0.111111111111111	0.50024154589372	0.973033875974509	1
GO:0015078	proton transmembrane transporter activity	31/4140	185/18639	0.167567567567568	0.754418331374853	0.973243324002682	1
GO:0003730	mRNA 3'-UTR binding	46/4140	262/18639	0.175572519083969	0.790458015267176	0.973823107517152	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	19/4140	122/18639	0.155737704918033	0.70115823235923	0.973836932319894	1
GO:0001216	DNA-binding transcription activator activity	92/4140	491/18639	0.187372708757637	0.843584521384929	0.975057487367854	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/4140	30/18639	0.1	0.450217391304348	0.97603827297593	1
GO:0033612	receptor serine/threonine kinase binding	3/4140	30/18639	0.1	0.450217391304348	0.97603827297593	1
GO:0004602	glutathione peroxidase activity	2/4140	23/18639	0.0869565217391304	0.391493383742911	0.976617736647509	1
GO:0004089	carbonate dehydratase activity	1/4140	15/18639	0.0666666666666667	0.300144927536232	0.976930794742477	1
GO:0004129	cytochrome-c oxidase activity	1/4140	15/18639	0.0666666666666667	0.300144927536232	0.976930794742477	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/4140	15/18639	0.0666666666666667	0.300144927536232	0.976930794742477	1
GO:0010181	FMN binding	1/4140	15/18639	0.0666666666666667	0.300144927536232	0.976930794742477	1
GO:0015116	sulfate transmembrane transporter activity	1/4140	15/18639	0.0666666666666667	0.300144927536232	0.976930794742477	1
GO:0015250	water channel activity	1/4140	15/18639	0.0666666666666667	0.300144927536232	0.976930794742477	1
GO:0031005	filamin binding	1/4140	15/18639	0.0666666666666667	0.300144927536232	0.976930794742477	1
GO:0045504	dynein heavy chain binding	1/4140	15/18639	0.0666666666666667	0.300144927536232	0.976930794742477	1
GO:0140161	monocarboxylate:sodium symporter activity	1/4140	15/18639	0.0666666666666667	0.300144927536232	0.976930794742477	1
GO:0030551	cyclic nucleotide binding	4/4140	37/18639	0.108108108108108	0.486721504112808	0.977391904204924	1
GO:0140375	immune receptor activity	25/4140	156/18639	0.16025641025641	0.721502229654404	0.97848327091081	1
GO:0003777	microtubule motor activity	9/4140	68/18639	0.132352941176471	0.595875959079284	0.978678931280132	1
GO:0048029	monosaccharide binding	10/4140	74/18639	0.135135135135135	0.608401880141011	0.979197584026146	1
GO:0015297	antiporter activity	21/4140	135/18639	0.155555555555556	0.700338164251208	0.97920751962972	1
GO:0005496	steroid binding	16/4140	108/18639	0.148148148148148	0.666988727858293	0.979677289948303	1
GO:0005452	solute:inorganic anion antiporter activity	3/4140	31/18639	0.0967741935483871	0.435694249649369	0.98023635629299	1
GO:0000146	microfilament motor activity	4/4140	38/18639	0.105263157894737	0.473913043478261	0.981079995533028	1
GO:0005109	frizzled binding	4/4140	38/18639	0.105263157894737	0.473913043478261	0.981079995533028	1
GO:0004806	triacylglycerol lipase activity	2/4140	24/18639	0.0833333333333333	0.37518115942029	0.981130359415544	1
GO:0005540	hyaluronic acid binding	2/4140	24/18639	0.0833333333333333	0.37518115942029	0.981130359415544	1
GO:0050431	transforming growth factor beta binding	2/4140	24/18639	0.0833333333333333	0.37518115942029	0.981130359415544	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/4140	24/18639	0.0833333333333333	0.37518115942029	0.981130359415544	1
GO:0004601	peroxidase activity	7/4140	57/18639	0.12280701754386	0.552898550724638	0.981319683884303	1
GO:0005024	transforming growth factor beta receptor activity	1/4140	16/18639	0.0625	0.281385869565217	0.982058936375109	1
GO:0015378	sodium:chloride symporter activity	1/4140	16/18639	0.0625	0.281385869565217	0.982058936375109	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/4140	16/18639	0.0625	0.281385869565217	0.982058936375109	1
GO:0016722	oxidoreductase activity, acting on metal ions	1/4140	16/18639	0.0625	0.281385869565217	0.982058936375109	1
GO:0055102	lipase inhibitor activity	1/4140	16/18639	0.0625	0.281385869565217	0.982058936375109	1
GO:0042910	xenobiotic transmembrane transporter activity	3/4140	32/18639	0.09375	0.422078804347826	0.983726261217301	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	9/4140	70/18639	0.128571428571429	0.578850931677019	0.983864487308606	1
GO:0016782	transferase activity, transferring sulphur-containing groups	9/4140	70/18639	0.128571428571429	0.578850931677019	0.983864487308606	1
GO:0005080	protein kinase C binding	6/4140	52/18639	0.115384615384615	0.519481605351171	0.984435149778724	1
GO:0000030	mannosyltransferase activity	2/4140	25/18639	0.08	0.360173913043478	0.984792440615857	1
GO:0001848	complement binding	2/4140	25/18639	0.08	0.360173913043478	0.984792440615857	1
GO:0005537	D-mannose binding	2/4140	25/18639	0.08	0.360173913043478	0.984792440615857	1
GO:0008484	sulfuric ester hydrolase activity	1/4140	17/18639	0.0588235294117647	0.264833759590793	0.986047337997138	1
GO:0030169	low-density lipoprotein particle binding	1/4140	17/18639	0.0588235294117647	0.264833759590793	0.986047337997138	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/4140	17/18639	0.0588235294117647	0.264833759590793	0.986047337997138	1
GO:0045236	CXCR chemokine receptor binding	1/4140	17/18639	0.0588235294117647	0.264833759590793	0.986047337997138	1
GO:0070492	oligosaccharide binding	1/4140	17/18639	0.0588235294117647	0.264833759590793	0.986047337997138	1
GO:0005227	calcium-activated cation channel activity	2/4140	26/18639	0.0769230769230769	0.346321070234114	0.987759085762865	1
GO:0042379	chemokine receptor binding	9/4140	72/18639	0.125	0.562771739130435	0.98786126282743	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	3/4140	34/18639	0.0882352941176471	0.397250639386189	0.989017638728483	1
GO:0140828	metal cation:monoatomic cation antiporter activity	4/4140	41/18639	0.0975609756097561	0.439236479321315	0.989022372310719	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/4140	18/18639	0.0555555555555556	0.25012077294686	0.989149261565597	1
GO:0005372	water transmembrane transporter activity	1/4140	18/18639	0.0555555555555556	0.25012077294686	0.989149261565597	1
GO:0015373	monoatomic anion:sodium symporter activity	1/4140	18/18639	0.0555555555555556	0.25012077294686	0.989149261565597	1
GO:0034185	apolipoprotein binding	1/4140	18/18639	0.0555555555555556	0.25012077294686	0.989149261565597	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/4140	18/18639	0.0555555555555556	0.25012077294686	0.989149261565597	1
GO:0033293	monocarboxylic acid binding	10/4140	79/18639	0.126582278481013	0.56989543203082	0.989505326441489	1
GO:0004620	phospholipase activity	15/4140	109/18639	0.137614678899083	0.619565217391304	0.990702501196103	1
GO:0005343	organic acid:sodium symporter activity	3/4140	35/18639	0.0857142857142857	0.385900621118012	0.990997706263657	1
GO:0005229	intracellularly calcium-gated chloride channel activity	1/4140	19/18639	0.0526315789473684	0.23695652173913	0.991561702203502	1
GO:0030506	ankyrin binding	1/4140	19/18639	0.0526315789473684	0.23695652173913	0.991561702203502	1
GO:0034987	immunoglobulin receptor binding	1/4140	19/18639	0.0526315789473684	0.23695652173913	0.991561702203502	1
GO:0042834	peptidoglycan binding	1/4140	19/18639	0.0526315789473684	0.23695652173913	0.991561702203502	1
GO:0043395	heparan sulfate proteoglycan binding	1/4140	19/18639	0.0526315789473684	0.23695652173913	0.991561702203502	1
GO:0141147	intracellularly calcium-gated channel activity	1/4140	19/18639	0.0526315789473684	0.23695652173913	0.991561702203502	1
GO:0170055	lipid transmembrane transporter activity	6/4140	56/18639	0.107142857142857	0.482375776397515	0.991912976512931	1
GO:0015101	organic cation transmembrane transporter activity	10/4140	81/18639	0.123456790123457	0.555823939881911	0.99209426274054	1
GO:0050698	proteoglycan sulfotransferase activity	2/4140	28/18639	0.0714285714285714	0.321583850931677	0.992096179770598	1
GO:0051959	dynein light intermediate chain binding	2/4140	28/18639	0.0714285714285714	0.321583850931677	0.992096179770598	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/4140	20/18639	0.05	0.225108695652174	0.993437886568567	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/4140	20/18639	0.05	0.225108695652174	0.993437886568567	1
GO:0030627	pre-mRNA 5'-splice site binding	1/4140	20/18639	0.05	0.225108695652174	0.993437886568567	1
GO:0016247	channel regulator activity	25/4140	168/18639	0.148809523809524	0.66996635610766	0.993567801190499	1
GO:0004181	metallocarboxypeptidase activity	2/4140	29/18639	0.0689655172413793	0.310494752623688	0.993658860284779	1
GO:0051861	glycolipid binding	2/4140	29/18639	0.0689655172413793	0.310494752623688	0.993658860284779	1
GO:0030280	structural constituent of skin epidermis	3/4140	37/18639	0.0810810810810811	0.365041128084606	0.993975388586215	1
GO:0042805	actinin binding	3/4140	37/18639	0.0810810810810811	0.365041128084606	0.993975388586215	1
GO:0001540	amyloid-beta binding	10/4140	83/18639	0.120481927710843	0.542430591932949	0.994075016079156	1
GO:0008009	chemokine activity	4/4140	45/18639	0.0888888888888889	0.400193236714976	0.994797949737741	1
GO:0141108	transporter regulator activity	25/4140	170/18639	0.147058823529412	0.662084398976982	0.994805447421666	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	27/4140	181/18639	0.149171270718232	0.671595003603171	0.994819125100841	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	5/4140	52/18639	0.0961538461538462	0.432901337792642	0.994862525213331	1
GO:0015125	bile acid transmembrane transporter activity	1/4140	21/18639	0.0476190476190476	0.214389233954451	0.994896995522116	1
GO:0001968	fibronectin binding	2/4140	30/18639	0.0666666666666667	0.300144927536232	0.994917473663982	1
GO:0022839	monoatomic ion-gated channel activity	2/4140	30/18639	0.0666666666666667	0.300144927536232	0.994917473663982	1
GO:0048019	receptor antagonist activity	2/4140	30/18639	0.0666666666666667	0.300144927536232	0.994917473663982	1
GO:0015459	potassium channel regulator activity	6/4140	59/18639	0.101694915254237	0.457848194546794	0.995125201360325	1
GO:0099106	ion channel regulator activity	23/4140	160/18639	0.14375	0.6471875	0.995382921525632	1
GO:0017147	Wnt-protein binding	2/4140	31/18639	0.0645161290322581	0.290462833099579	0.995929964517154	1
GO:0047499	calcium-independent phospholipase A2 activity	2/4140	31/18639	0.0645161290322581	0.290462833099579	0.995929964517154	1
GO:0015377	chloride:monoatomic cation symporter activity	1/4140	22/18639	0.0454545454545455	0.204644268774704	0.996031727423418	1
GO:0033038	bitter taste receptor activity	1/4140	22/18639	0.0454545454545455	0.204644268774704	0.996031727423418	1
GO:0016209	antioxidant activity	10/4140	86/18639	0.116279069767442	0.523508594539939	0.996190833667086	1
GO:0047498	calcium-dependent phospholipase A2 activity	2/4140	32/18639	0.0625	0.281385869565217	0.996743544737144	1
GO:0071813	lipoprotein particle binding	2/4140	32/18639	0.0625	0.281385869565217	0.996743544737144	1
GO:0071814	protein-lipid complex binding	2/4140	32/18639	0.0625	0.281385869565217	0.996743544737144	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/4140	23/18639	0.0434782608695652	0.195746691871456	0.996914181549596	1
GO:0005212	structural constituent of eye lens	1/4140	23/18639	0.0434782608695652	0.195746691871456	0.996914181549596	1
GO:0099186	structural constituent of postsynapse	1/4140	23/18639	0.0434782608695652	0.195746691871456	0.996914181549596	1
GO:0098632	cell-cell adhesion mediator activity	5/4140	55/18639	0.0909090909090909	0.409288537549407	0.997013732003977	1
GO:0017080	sodium channel regulator activity	3/4140	41/18639	0.0731707317073171	0.329427359490986	0.997340145907714	1
GO:1901682	sulfur compound transmembrane transporter activity	6/4140	63/18639	0.0952380952380952	0.428778467908903	0.997561991880974	1
GO:0004622	lysophospholipase activity	1/4140	24/18639	0.0416666666666667	0.187590579710145	0.997600434685859	1
GO:0015171	amino acid transmembrane transporter activity	12/4140	102/18639	0.117647058823529	0.529667519181586	0.997789826089913	1
GO:0042056	chemoattractant activity	3/4140	42/18639	0.0714285714285714	0.321583850931677	0.997837649046952	1
GO:0005251	delayed rectifier potassium channel activity	1/4140	25/18639	0.04	0.180086956521739	0.998134101105442	1
GO:0015271	outward rectifier potassium channel activity	1/4140	25/18639	0.04	0.180086956521739	0.998134101105442	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/4140	25/18639	0.04	0.180086956521739	0.998134101105442	1
GO:0004623	phospholipase A2 activity	2/4140	35/18639	0.0571428571428571	0.257267080745342	0.998339836820784	1
GO:0061134	peptidase regulator activity	33/4140	226/18639	0.146017699115044	0.657397075798384	0.998544509909696	1
GO:0019865	immunoglobulin binding	1/4140	26/18639	0.0384615384615385	0.173160535117057	0.998549101719145	1
GO:0016298	lipase activity	16/4140	130/18639	0.123076923076923	0.554113712374582	0.998704784550318	1
GO:0046943	carboxylic acid transmembrane transporter activity	26/4140	188/18639	0.138297872340426	0.622641073080481	0.998705625939591	1
GO:0005506	iron ion binding	20/4140	154/18639	0.12987012987013	0.584697910784867	0.998770412843267	1
GO:0005342	organic acid transmembrane transporter activity	26/4140	189/18639	0.137566137566138	0.619346675868415	0.998847699701837	1
GO:0015252	proton channel activity	1/4140	27/18639	0.037037037037037	0.166747181964573	0.998871818040143	1
GO:0043394	proteoglycan binding	2/4140	37/18639	0.0540540540540541	0.243360752056404	0.99894425073305	1
GO:0005242	inward rectifier potassium channel activity	1/4140	28/18639	0.0357142857142857	0.160791925465839	0.999122767605682	1
GO:0008527	taste receptor activity	1/4140	28/18639	0.0357142857142857	0.160791925465839	0.999122767605682	1
GO:0051393	alpha-actinin binding	1/4140	28/18639	0.0357142857142857	0.160791925465839	0.999122767605682	1
GO:0005501	retinoid binding	2/4140	38/18639	0.0526315789473684	0.23695652173913	0.99915889199651	1
GO:0019840	isoprenoid binding	2/4140	38/18639	0.0526315789473684	0.23695652173913	0.99915889199651	1
GO:0005253	monoatomic anion channel activity	11/4140	103/18639	0.106796116504854	0.480814689742507	0.999257381967136	1
GO:0015085	calcium ion transmembrane transporter activity	18/4140	147/18639	0.122448979591837	0.551286601597161	0.999345360499563	1
GO:0098918	structural constituent of synapse	1/4140	30/18639	0.0333333333333333	0.150072463768116	0.999469646238681	1
GO:0005178	integrin binding	20/4140	161/18639	0.124223602484472	0.559276262489873	0.999503934838993	1
GO:0005518	collagen binding	6/4140	72/18639	0.0833333333333333	0.37518115942029	0.999519237227965	1
GO:0005262	calcium channel activity	15/4140	131/18639	0.114503816793893	0.515516096913375	0.999520461777633	1
GO:0019842	vitamin binding	18/4140	150/18639	0.12	0.540260869565217	0.999565179033974	1
GO:0008227	G protein-coupled amine receptor activity	2/4140	41/18639	0.0487804878048781	0.219618239660657	0.999576144792091	1
GO:0031406	carboxylic acid binding	24/4140	187/18639	0.128342245989305	0.577819111834457	0.999637714020156	1
GO:0015106	bicarbonate transmembrane transporter activity	1/4140	32/18639	0.03125	0.140692934782609	0.99967938049689	1
GO:0043177	organic acid binding	24/4140	189/18639	0.126984126984127	0.571704623878537	0.999719114767413	1
GO:0033218	amide binding	34/4140	247/18639	0.137651821862348	0.619732441471572	0.999733799730547	1
GO:0042923	neuropeptide binding	1/4140	33/18639	0.0303030303030303	0.136429512516469	0.999750717345542	1
GO:0019838	growth factor binding	15/4140	136/18639	0.110294117647059	0.496563299232737	0.999769815874966	1
GO:0098631	cell adhesion mediator activity	6/4140	76/18639	0.0789473684210526	0.355434782608696	0.999772035377452	1
GO:0030547	signaling receptor inhibitor activity	2/4140	44/18639	0.0454545454545455	0.204644268774704	0.99978740889013	1
GO:0008146	sulfotransferase activity	3/4140	53/18639	0.0566037735849057	0.254840032813782	0.999790601522784	1
GO:0008514	organic anion transmembrane transporter activity	37/4140	269/18639	0.137546468401487	0.619258121868434	0.999850125296716	1
GO:0015370	solute:sodium symporter activity	6/4140	79/18639	0.0759493670886076	0.341937259218492	0.999870860552176	1
GO:0022804	active transmembrane transporter activity	71/4140	457/18639	0.155361050328228	0.699462467890781	0.999878751983266	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/4140	36/18639	0.0277777777777778	0.12506038647343	0.999882845668396	1
GO:0042562	hormone binding	8/4140	94/18639	0.0851063829787234	0.383163737280296	0.999883586380119	1
GO:0061135	endopeptidase regulator activity	22/4140	184/18639	0.119565217391304	0.538303402646503	0.999887080273843	1
GO:0099095	ligand-gated monoatomic anion channel activity	2/4140	47/18639	0.0425531914893617	0.191581868640148	0.999893811642416	1
GO:0015294	solute:monoatomic cation symporter activity	11/4140	116/18639	0.0948275862068965	0.426930284857571	0.99990882278078	1
GO:0030246	carbohydrate binding	38/4140	280/18639	0.135714285714286	0.611009316770186	0.999918681723667	1
GO:0015293	symporter activity	15/4140	146/18639	0.102739726027397	0.462552114353782	0.999949852106966	1
GO:0071855	neuropeptide receptor binding	1/4140	40/18639	0.025	0.112554347826087	0.999957202357169	1
GO:0005003	ephrin receptor activity	2/4140	53/18639	0.0377358490566038	0.169893355209188	0.999973786682911	1
GO:0005005	transmembrane-ephrin receptor activity	2/4140	53/18639	0.0377358490566038	0.169893355209188	0.999973786682911	1
GO:0008307	structural constituent of muscle	1/4140	42/18639	0.0238095238095238	0.107194616977226	0.99997413511866	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/4140	44/18639	0.0227272727272727	0.102322134387352	0.999984369445598	1
GO:0038024	cargo receptor activity	3/4140	65/18639	0.0461538461538462	0.207792642140468	0.999985005334759	1
GO:0003823	antigen binding	18/4140	174/18639	0.103448275862069	0.465742128935532	0.999986905509625	1
GO:0008509	monoatomic anion transmembrane transporter activity	14/4140	149/18639	0.0939597315436242	0.423023052232273	0.999989212329028	1
GO:0001664	G protein-coupled receptor binding	38/4140	297/18639	0.127946127946128	0.57603571951398	0.999989382284597	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/4140	46/18639	0.0217391304347826	0.0978733459357278	0.99999055479215	1
GO:0015291	secondary active transmembrane transporter activity	36/4140	287/18639	0.125435540069686	0.564732616270262	0.99999143346024	1
GO:0008188	neuropeptide receptor activity	1/4140	48/18639	0.0208333333333333	0.0937952898550725	0.99999429281573	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	2/4140	60/18639	0.0333333333333333	0.150072463768116	0.999994950527012	1
GO:0005004	GPI-linked ephrin receptor activity	1/4140	49/18639	0.0204081632653061	0.0918811002661934	0.99999556373945	1
GO:0005008	hepatocyte growth factor receptor activity	1/4140	49/18639	0.0204081632653061	0.0918811002661934	0.99999556373945	1
GO:0005009	insulin receptor activity	1/4140	49/18639	0.0204081632653061	0.0918811002661934	0.99999556373945	1
GO:0005011	macrophage colony-stimulating factor receptor activity	1/4140	49/18639	0.0204081632653061	0.0918811002661934	0.99999556373945	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/4140	49/18639	0.0204081632653061	0.0918811002661934	0.99999556373945	1
GO:0005020	stem cell factor receptor activity	1/4140	49/18639	0.0204081632653061	0.0918811002661934	0.99999556373945	1
GO:0008288	boss receptor activity	1/4140	49/18639	0.0204081632653061	0.0918811002661934	0.99999556373945	1
GO:0036332	placental growth factor receptor activity	1/4140	49/18639	0.0204081632653061	0.0918811002661934	0.99999556373945	1
GO:0038062	protein tyrosine kinase collagen receptor activity	1/4140	49/18639	0.0204081632653061	0.0918811002661934	0.99999556373945	1
GO:0060175	brain-derived neurotrophic factor receptor activity	1/4140	49/18639	0.0204081632653061	0.0918811002661934	0.99999556373945	1
GO:0008236	serine-type peptidase activity	20/4140	194/18639	0.103092783505155	0.464141640519946	0.999995628065433	1
GO:0020037	heme binding	12/4140	142/18639	0.0845070422535211	0.380465401102266	0.999996545633669	1
GO:0005006	epidermal growth factor receptor activity	1/4140	50/18639	0.02	0.0900434782608696	0.999996551696345	1
GO:0005007	fibroblast growth factor receptor activity	1/4140	50/18639	0.02	0.0900434782608696	0.999996551696345	1
GO:0005017	platelet-derived growth factor receptor activity	1/4140	50/18639	0.02	0.0900434782608696	0.999996551696345	1
GO:0005019	platelet-derived growth factor beta-receptor activity	1/4140	50/18639	0.02	0.0900434782608696	0.999996551696345	1
GO:0004252	serine-type endopeptidase activity	17/4140	176/18639	0.0965909090909091	0.434869071146245	0.999996567074465	1
GO:0005010	insulin-like growth factor receptor activity	1/4140	51/18639	0.0196078431372549	0.0882779198635976	0.999997319676179	1
GO:0005021	vascular endothelial growth factor receptor activity	1/4140	51/18639	0.0196078431372549	0.0882779198635976	0.999997319676179	1
GO:0005030	neurotrophin receptor activity	1/4140	51/18639	0.0196078431372549	0.0882779198635976	0.999997319676179	1
GO:0017171	serine hydrolase activity	20/4140	198/18639	0.101010101010101	0.454765041721563	0.999997640840693	1
GO:0005254	chloride channel activity	4/4140	83/18639	0.0481927710843374	0.21697223677318	0.999997922458174	1
GO:0046906	tetrapyrrole binding	13/4140	152/18639	0.0855263157894737	0.385054347826087	0.999997956563909	1
GO:0017046	peptide hormone binding	1/4140	53/18639	0.0188679245283019	0.0849466776045939	0.999998380687348	1
GO:0038064	collagen receptor activity	1/4140	53/18639	0.0188679245283019	0.0849466776045939	0.999998380687348	1
GO:0004866	endopeptidase inhibitor activity	14/4140	161/18639	0.0869565217391304	0.391493383742911	0.999998567805393	1
GO:0016500	protein-hormone receptor activity	2/4140	67/18639	0.0298507462686567	0.134393251135626	0.999999039864567	1
GO:0019199	transmembrane receptor protein kinase activity	3/4140	78/18639	0.0384615384615385	0.173160535117057	0.999999198380205	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/4140	56/18639	0.0178571428571429	0.0803959627329193	0.999999239681338	1
GO:0030414	peptidase inhibitor activity	14/4140	169/18639	0.0828402366863905	0.372961152559815	0.999999642628989	1
GO:1901681	sulfur compound binding	30/4140	275/18639	0.109090909090909	0.491146245059288	0.999999685999682	1
GO:0015103	inorganic anion transmembrane transporter activity	13/4140	165/18639	0.0787878787878788	0.354716732542819	0.999999794638227	1
GO:0005125	cytokine activity	23/4140	234/18639	0.0982905982905983	0.442521367521368	0.999999820087051	1
GO:0004497	monooxygenase activity	5/4140	106/18639	0.0471698113207547	0.212366694011485	0.999999902043681	1
GO:0098960	postsynaptic neurotransmitter receptor activity	1/4140	69/18639	0.0144927536231884	0.0652488972904852	0.999999971324338	1
GO:0015108	chloride transmembrane transporter activity	6/4140	121/18639	0.0495867768595041	0.223248293208768	0.99999997411877	1
GO:0004867	serine-type endopeptidase inhibitor activity	3/4140	95/18639	0.0315789473684211	0.142173913043478	0.999999983933261	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/4140	73/18639	0.0136986301369863	0.0616736152471709	0.999999989545798	1
GO:0005249	voltage-gated potassium channel activity	3/4140	98/18639	0.0306122448979592	0.13782165039929	0.999999992000253	1
GO:0099094	ligand-gated monoatomic cation channel activity	6/4140	136/18639	0.0441176470588235	0.198625319693095	0.999999998962625	1
GO:0030594	neurotransmitter receptor activity	2/4140	97/18639	0.0206185567010309	0.0928283281039892	0.999999999294786	1
GO:0015081	sodium ion transmembrane transporter activity	9/4140	164/18639	0.0548780487804878	0.24707051961824	0.999999999337189	1
GO:0005179	hormone activity	5/4140	132/18639	0.0378787878787879	0.170536890645586	0.999999999675841	1
GO:0005244	voltage-gated monoatomic ion channel activity	9/4140	173/18639	0.0520231213872832	0.234217139984921	0.999999999896137	1
GO:0001653	peptide receptor activity	4/4140	128/18639	0.03125	0.140692934782609	0.999999999914795	1
GO:0022832	voltage-gated channel activity	9/4140	175/18639	0.0514285714285714	0.231540372670807	0.999999999931417	1
GO:0008528	G protein-coupled peptide receptor activity	3/4140	122/18639	0.0245901639344262	0.110709194583036	0.999999999971566	1
GO:0008083	growth factor activity	7/4140	162/18639	0.0432098765432099	0.194538378958669	0.999999999973624	1
GO:0008201	heparin binding	8/4140	172/18639	0.0465116279069767	0.209403437815976	0.999999999979048	1
GO:0005267	potassium channel activity	3/4140	124/18639	0.0241935483870968	0.108923562412342	0.999999999982302	1
GO:0015079	potassium ion transmembrane transporter activity	6/4140	160/18639	0.0375	0.16883152173913	0.999999999994678	1
GO:0005539	glycosaminoglycan binding	15/4140	242/18639	0.0619834710743802	0.279060366510959	0.999999999998255	1
GO:0015276	ligand-gated monoatomic ion channel activity	8/4140	186/18639	0.043010752688172	0.193641888733053	0.999999999998961	1
GO:0005549	odorant binding	1/4140	111/18639	0.00900900900900901	0.040560125342734	0.999999999999291	1
GO:0022834	ligand-gated channel activity	8/4140	188/18639	0.0425531914893617	0.191581868640148	0.999999999999326	1
GO:0022843	voltage-gated monoatomic cation channel activity	3/4140	143/18639	0.020979020979021	0.0944512009729401	0.999999999999809	1
GO:0046873	metal ion transmembrane transporter activity	39/4140	450/18639	0.0866666666666667	0.390188405797101	0.999999999999997	1
GO:0004984	olfactory receptor activity	2/4140	419/18639	0.00477326968973747	0.0214900902770572	1	1
GO:0005201	extracellular matrix structural constituent	1/4140	168/18639	0.00595238095238095	0.0267986542443064	1	1
GO:0005216	monoatomic ion channel activity	33/4140	448/18639	0.0736607142857143	0.331633346273292	1	1
GO:0005261	monoatomic cation channel activity	21/4140	341/18639	0.06158357771261	0.277259977049598	1	1
GO:0022836	gated channel activity	17/4140	318/18639	0.0534591194968553	0.240682253213016	1	1
GO:0030371	translation repressor activity	8/4140	329/18639	0.0243161094224924	0.109475353508656	1	1
GO:0045182	translation regulator activity	13/4140	356/18639	0.0365168539325843	0.1644052271617	1	1