ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	222/4384	495/18639	0.448484848484848	1.90677670869277	3.56528615404897e-26	4.62061085564747e-23
GO:0019787	ubiquitin-like protein transferase activity	197/4384	479/18639	0.411273486430063	1.74856900400774	3.77745275487245e-18	2.44778938515735e-15
GO:0016755	aminoacyltransferase activity	199/4384	496/18639	0.401209677419355	1.70578174667412	6.04256312505846e-17	2.61038727002525e-14
GO:0004842	ubiquitin-protein transferase activity	179/4384	449/18639	0.398663697104677	1.69495726513095	4.6488284296331e-15	1.50622041120112e-12
GO:0008094	ATP-dependent activity, acting on DNA	100/4384	210/18639	0.476190476190476	2.02456986444213	1.5713119530299e-14	4.0728405822535e-12
GO:0042393	histone binding	112/4384	247/18639	0.453441295546559	1.92784952274003	3.03751862230271e-14	5.81323646241347e-12
GO:0061775	cohesin loader activity	79/4384	153/18639	0.516339869281046	2.19526889222842	3.81580269496973e-14	5.81323646241347e-12
GO:0000510	H3-H4 histone complex chaperone activity	78/4384	151/18639	0.516556291390728	2.19618903175908	5.3665024079714e-14	5.81323646241347e-12
GO:0140584	chromatin extrusion motor activity	78/4384	151/18639	0.516556291390728	2.19618903175908	5.3665024079714e-14	5.81323646241347e-12
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	78/4384	151/18639	0.516556291390728	2.19618903175908	5.3665024079714e-14	5.81323646241347e-12
GO:0140849	ATP-dependent H2AZ histone chaperone activity	78/4384	151/18639	0.516556291390728	2.19618903175908	5.3665024079714e-14	5.81323646241347e-12
GO:0016887	ATP hydrolysis activity	166/4384	417/18639	0.398081534772182	1.69248214567033	5.38262635408654e-14	5.81323646241347e-12
GO:0003689	DNA clamp loader activity	81/4384	160/18639	0.50625	2.15237083713504	7.49209777527229e-14	6.88528978837088e-12
GO:0140097	catalytic activity, acting on DNA	140/4384	336/18639	0.416666666666667	1.77149863138686	8.42502139424501e-14	6.88528978837088e-12
GO:0015616	DNA translocase activity	78/4384	152/18639	0.513157894736842	2.18174041970803	8.50035776342084e-14	6.88528978837088e-12
GO:0140674	ATP-dependent histone chaperone activity	78/4384	152/18639	0.513157894736842	2.18174041970803	8.50035776342084e-14	6.88528978837088e-12
GO:0140658	ATP-dependent chromatin remodeler activity	80/4384	158/18639	0.506329113924051	2.15270719763467	1.05461687347843e-13	8.03990275310614e-12
GO:0140713	histone chaperone activity	82/4384	164/18639	0.5	2.12579835766423	1.2736454032886e-13	9.17024690367794e-12
GO:0003713	transcription coactivator activity	113/4384	256/18639	0.44140625	1.87668136262546	2.21622144906776e-13	1.51169631473254e-11
GO:0044389	ubiquitin-like protein ligase binding	134/4384	322/18639	0.416149068322981	1.76929801196899	3.20495427258414e-13	2.07681036863452e-11
GO:0140104	molecular carrier activity	110/4384	249/18639	0.441767068273092	1.87821541641017	4.31296627444731e-13	2.6617163293732e-11
GO:0140597	protein carrier chaperone	89/4384	188/18639	0.473404255319149	2.01272397693741	6.59378972464773e-13	3.88434158324703e-11
GO:0140098	catalytic activity, acting on RNA	153/4384	387/18639	0.395348837209302	1.680863817688	1.00767249240755e-12	5.67801543547909e-11
GO:0004386	helicase activity	77/4384	155/18639	0.496774193548387	2.11208352955027	1.07937209914529e-12	5.82860933538458e-11
GO:0140297	DNA-binding transcription factor binding	182/4384	488/18639	0.372950819672131	1.58563647989709	3.40594764106954e-12	1.76564325713045e-10
GO:0061659	ubiquitin-like protein ligase activity	146/4384	372/18639	0.39247311827957	1.66863742053214	6.37121747401977e-12	3.17580686397293e-10
GO:0031625	ubiquitin protein ligase binding	124/4384	302/18639	0.410596026490066	1.74568871755209	7.30933681736933e-12	3.38856366125042e-10
GO:0043021	ribonucleoprotein complex binding	83/4384	177/18639	0.468926553672316	1.99368659532352	7.32097087307189e-12	3.38856366125042e-10
GO:0070063	RNA polymerase binding	37/4384	59/18639	0.627118644067797	2.66625556723989	1.52734613910255e-10	6.82565722854104e-09
GO:0016779	nucleotidyltransferase activity	65/4384	136/18639	0.477941176470588	2.03201313600258	4.94504840739433e-10	2.13626091199435e-08
GO:0061630	ubiquitin protein ligase activity	134/4384	353/18639	0.379603399433428	1.61392056615868	6.44006687871284e-10	2.67849731398235e-08
GO:0031072	heat shock protein binding	63/4384	131/18639	0.480916030534351	2.04466101576865	6.61357361477124e-10	2.67849731398235e-08
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	75/4384	167/18639	0.449101796407186	1.9093997224529	8.87647009992521e-10	3.48603189378881e-08
GO:0003725	double-stranded RNA binding	42/4384	75/18639	0.56	2.38089416058394	1.39001866924919e-09	5.14704055813413e-08
GO:0044183	protein folding chaperone	42/4384	75/18639	0.56	2.38089416058394	1.39001866924919e-09	5.14704055813413e-08
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	131/4384	349/18639	0.375358166189112	1.59587154644134	2.29262641208941e-09	8.22056693486772e-08
GO:0140030	modification-dependent protein binding	76/4384	173/18639	0.439306358381503	1.86775347031771	2.3469211156644e-09	8.22056693486772e-08
GO:0008186	ATP-dependent activity, acting on RNA	43/4384	79/18639	0.544303797468354	2.31416023745727	2.91947018437634e-09	9.95692989197826e-08
GO:0060589	nucleoside-triphosphatase regulator activity	172/4384	490/18639	0.351020408163265	1.4923972143602	3.05914257466599e-09	1.01657660942747e-07
GO:0043175	RNA polymerase core enzyme binding	28/4384	42/18639	0.666666666666667	2.83439781021898	3.47685427855277e-09	1.1265007862511e-07
GO:0003724	RNA helicase activity	42/4384	77/18639	0.545454545454545	2.31905275381553	4.08546553912818e-09	1.29140569236832e-07
GO:0030695	GTPase regulator activity	171/4384	489/18639	0.349693251533742	1.48675467959339	4.65952102017526e-09	1.43779505765408e-07
GO:0000993	RNA polymerase II complex binding	25/4384	36/18639	0.694444444444444	2.9524977189781	6.70244042150345e-09	2.02008436889965e-07
GO:0003714	transcription corepressor activity	84/4384	204/18639	0.411764705882353	1.7506574710176	1.45001183123472e-08	4.27094393927318e-07
GO:0032182	ubiquitin-like protein binding	56/4384	120/18639	0.466666666666667	1.98407846715328	2.23089201505093e-08	6.42496900334669e-07
GO:0004532	RNA exonuclease activity	26/4384	40/18639	0.65	2.7635378649635	2.81542846101596e-08	7.93216366407976e-07
GO:0051082	unfolded protein binding	56/4384	121/18639	0.462809917355372	1.96768112444954	3.20750428721312e-08	8.84452246006001e-07
GO:0001098	basal transcription machinery binding	34/4384	60/18639	0.566666666666667	2.40923813868613	3.39629827439503e-08	8.98286237472645e-07
GO:0001099	basal RNA polymerase II transcription machinery binding	34/4384	60/18639	0.566666666666667	2.40923813868613	3.39629827439503e-08	8.98286237472645e-07
GO:0008276	protein methyltransferase activity	46/4384	95/18639	0.484210526315789	2.05866788321168	9.95358688964535e-08	2.57996972179607e-06
GO:0046966	nuclear thyroid hormone receptor binding	20/4384	28/18639	0.714285714285714	3.03685479666319	1.07552552971052e-07	2.73310016961732e-06
GO:0008168	methyltransferase activity	81/4384	204/18639	0.397058823529412	1.68813398990983	1.69588251200478e-07	4.22666102991961e-06
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	24/4384	38/18639	0.631578947368421	2.68521897810219	2.16675900026675e-07	5.29833898933152e-06
GO:0016741	transferase activity, transferring one-carbon groups	84/4384	215/18639	0.390697674418605	1.66108894924461	2.30861566773475e-07	5.5406776025634e-06
GO:0043022	ribosome binding	51/4384	112/18639	0.455357142857143	1.93599493287278	2.45465035091352e-07	5.75419659694674e-06
GO:0003697	single-stranded DNA binding	54/4384	121/18639	0.446280991735537	1.89740679857634	2.48638124559427e-07	5.75419659694674e-06
GO:0051087	protein-folding chaperone binding	58/4384	134/18639	0.432835820895522	1.8402433543959	3.27132515598854e-07	7.43796035466868e-06
GO:0004527	exonuclease activity	41/4384	84/18639	0.488095238095238	2.07518411105318	3.69834601407254e-07	8.26389040385864e-06
GO:0140463	chromatin-protein adaptor activity	30/4384	54/18639	0.555555555555556	2.36199817518248	3.90684106584347e-07	8.58180681581887e-06
GO:0000175	3'-5'-RNA exonuclease activity	22/4384	35/18639	0.628571428571429	2.67243222106361	7.87388765977202e-07	1.69888561593022e-05
GO:0016922	nuclear receptor binding	58/4384	137/18639	0.423357664233577	1.79994605466461	7.99629803794317e-07	1.69888561593022e-05
GO:0140662	ATP-dependent protein folding chaperone	24/4384	40/18639	0.6	2.55095802919708	8.49712390191357e-07	1.74987032927775e-05
GO:0003727	single-stranded RNA binding	42/4384	89/18639	0.471910112359551	2.00637148363815	8.50631410065575e-07	1.74987032927775e-05
GO:0008170	N-methyltransferase activity	45/4384	98/18639	0.459183673469388	1.95226379785491	9.18035693694687e-07	1.85902227973174e-05
GO:0106310	protein serine kinase activity	125/4384	361/18639	0.346260387811634	1.47215952746831	9.7120651257065e-07	1.93643636967933e-05
GO:0004674	protein serine/threonine kinase activity	145/4384	433/18639	0.334872979214781	1.42374485848182	1.24512977056889e-06	2.44498209493527e-05
GO:0061650	ubiquitin-like protein conjugating enzyme activity	24/4384	41/18639	0.585365853658537	2.48873954068008	1.59217680172595e-06	3.07979273886094e-05
GO:0001222	transcription corepressor binding	27/4384	49/18639	0.551020408163265	2.34271655742589	1.84199737417611e-06	3.51063028960624e-05
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	31/4384	60/18639	0.516666666666667	2.19665830291971	2.07157598865913e-06	3.89096011782932e-05
GO:0140857	histone H3T45 kinase activity	90/4384	246/18639	0.365853658536585	1.55546221292505	2.48185454754185e-06	4.59497641944892e-05
GO:0019207	kinase regulator activity	102/4384	287/18639	0.355400696864112	1.5110204354129	2.53543866831288e-06	4.62806832976549e-05
GO:0140938	histone H3 methyltransferase activity	26/4384	47/18639	0.553191489361702	2.35194711911788	2.58372983943624e-06	4.65071371098523e-05
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	89/4384	243/18639	0.366255144032922	1.55716916734252	2.67170043009392e-06	4.74318322931742e-05
GO:0035403	histone H3T6 kinase activity	90/4384	247/18639	0.364372469635628	1.54916479505896	3.01302228861447e-06	5.2768606568167e-05
GO:0005096	GTPase activator activity	97/4384	271/18639	0.357933579335793	1.52178923020982	3.11366513514435e-06	5.36623647877654e-05
GO:0140296	general transcription initiation factor binding	28/4384	53/18639	0.528301886792453	2.24612656658862	3.63171929334087e-06	5.36623647877654e-05
GO:0004679	AMP-activated protein kinase activity	90/4384	248/18639	0.362903225806452	1.54291816282081	3.64952477695894e-06	5.36623647877654e-05
GO:0042054	histone methyltransferase activity	33/4384	67/18639	0.492537313432836	2.09407002396775	3.86909995516311e-06	5.36623647877654e-05
GO:0004676	3-phosphoinositide-dependent protein kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0004711	ribosomal protein S6 kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0035175	histone H3S10 kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0035979	histone H2AXS139 kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0044022	histone H3S28 kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0044023	histone H4S1 kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0044024	histone H2AS1 kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0044025	histone H2BS14 kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0072354	histone H3T3 kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0072371	histone H2AS121 kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0072518	Rho-dependent protein serine/threonine kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0140823	histone H2BS36 kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0140855	histone H3S57 kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0140995	histone H2A kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0140997	histone H4 kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0140998	histone H2B kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:1990244	histone H2AT120 kinase activity	89/4384	245/18639	0.363265306122449	1.54445758230299	3.93358383860935e-06	5.36623647877654e-05
GO:0140566	histone reader activity	21/4384	35/18639	0.6	2.55095802919708	4.14302413506561e-06	5.59308258233857e-05
GO:0004677	DNA-dependent protein kinase activity	89/4384	246/18639	0.361788617886179	1.5381792994481	4.75653865966041e-06	6.35512794115453e-05
GO:0043130	ubiquitin binding	44/4384	100/18639	0.44	1.87070255474453	4.92346731810934e-06	6.51103433088745e-05
GO:0003743	translation initiation factor activity	27/4384	51/18639	0.529411764705882	2.25084531987978	5.12876284803255e-06	6.71401681924261e-05
GO:0042162	telomeric DNA binding	22/4384	38/18639	0.578947368421053	2.46145072992701	5.57969385457362e-06	7.23128323552742e-05
GO:0035402	histone H3T11 kinase activity	89/4384	247/18639	0.360323886639676	1.53195185289163	5.73864598259127e-06	7.36364870637455e-05
GO:0019902	phosphatase binding	72/4384	190/18639	0.378947368421053	1.61113138686131	5.91355321062369e-06	7.51369113820421e-05
GO:0008135	translation factor activity, RNA binding	38/4384	83/18639	0.457831325301205	1.94651415882508	6.87367781305068e-06	8.64882179195503e-05
GO:0015631	tubulin binding	128/4384	385/18639	0.332467532467532	1.41351786899232	7.655426311622e-06	9.5398389421751e-05
GO:0016279	protein-lysine N-methyltransferase activity	33/4384	69/18639	0.478260869565217	2.03337234211361	8.66058389329517e-06	0.000106896349768672
GO:0180051	translation factor activity	38/4384	84/18639	0.452380952380952	1.92334137122002	9.72345745488752e-06	0.000118883026995606
GO:0008408	3'-5' exonuclease activity	29/4384	58/18639	0.5	2.12579835766423	1.01514289359213e-05	0.00012295562524256
GO:0140517	protein-RNA adaptor activity	15/4384	22/18639	0.681818181818182	2.89881594226941	1.10506610797398e-05	0.000132607932956878
GO:0016278	lysine N-methyltransferase activity	33/4384	70/18639	0.471428571428571	2.00432416579771	1.27056746107559e-05	0.000151069305463666
GO:0019887	protein kinase regulator activity	90/4384	255/18639	0.352941176470588	1.50056354658652	1.31208538831634e-05	0.000154587514841634
GO:0140034	methylation-dependent protein binding	35/4384	76/18639	0.460526315789474	1.95797217153285	1.33502604371142e-05	0.000155873311049549
GO:0051059	NF-kappaB binding	19/4384	32/18639	0.59375	2.52438554972628	1.47947955899623e-05	0.000171196920398135
GO:0045309	protein phosphorylated amino acid binding	29/4384	59/18639	0.491525423728814	2.08976787702586	1.54975492719506e-05	0.000177741804039363
GO:0035064	methylated histone binding	34/4384	74/18639	0.459459459459459	1.95343632866443	1.87606664889458e-05	0.000213279155874331
GO:0031267	small GTPase binding	97/4384	283/18639	0.342756183745583	1.45726106497124	2.42250233380663e-05	0.000273005480401165
GO:0051219	phosphoprotein binding	40/4384	93/18639	0.43010752688172	1.82864374852837	2.50164323726645e-05	0.000279493934094597
GO:0051020	GTPase binding	105/4384	315/18639	0.333333333333333	1.41719890510949	4.28656809035269e-05	0.000474819850008298
GO:0019783	ubiquitin-like protein peptidase activity	50/4384	127/18639	0.393700787401575	1.67385697453877	4.72877126386383e-05	0.00051936335237013
GO:0045296	cadherin binding	110/4384	334/18639	0.329341317365269	1.40022646313213	5.0478312490801e-05	0.000549746999899816
GO:0003678	DNA helicase activity	33/4384	74/18639	0.445945945945946	1.89598231899783	5.22666803768318e-05	0.000559815022879124
GO:0031491	nucleosome binding	33/4384	74/18639	0.445945945945946	1.89598231899783	5.22666803768318e-05	0.000559815022879124
GO:0001221	transcription coregulator binding	46/4384	115/18639	0.4	1.70063868613139	5.91317292068821e-05	0.000628153451246879
GO:0031490	chromatin DNA binding	50/4384	128/18639	0.390625	1.66077996692518	6.00539053852772e-05	0.000632763100644872
GO:0030544	Hsp70 protein binding	25/4384	51/18639	0.490196078431373	2.08411603692572	6.25196101052845e-05	0.000653430763681038
GO:0046975	histone H3K36 methyltransferase activity	10/4384	13/18639	0.769230769230769	3.27045901179113	7.1680945193329e-05	0.000743188039764435
GO:0002039	p53 binding	31/4384	69/18639	0.449275362318841	1.91013765471279	7.3396277847339e-05	0.00075493314357263
GO:0140767	enzyme-substrate adaptor activity	53/4384	139/18639	0.381294964028777	1.62111241663603	7.83769591992876e-05	0.000799815268679344
GO:0010485	histone H4 acetyltransferase activity	19/4384	35/18639	0.542857142857143	2.30800964546402	8.19900510820244e-05	0.000830149267205497
GO:0060590	ATPase regulator activity	24/4384	49/18639	0.489795918367347	2.0824147177119	8.87294890562187e-05	0.000891421843541546
GO:0043995	histone H4K5 acetyltransferase activity	17/4384	30/18639	0.566666666666667	2.40923813868613	9.50643076197543e-05	0.000933358656630315
GO:0043996	histone H4K8 acetyltransferase activity	17/4384	30/18639	0.566666666666667	2.40923813868613	9.50643076197543e-05	0.000933358656630315
GO:0043997	histone H4K12 acetyltransferase activity	17/4384	30/18639	0.566666666666667	2.40923813868613	9.50643076197543e-05	0.000933358656630315
GO:0017025	TBP-class protein binding	15/4384	25/18639	0.6	2.55095802919708	0.000101343723537638	0.000987529817329162
GO:0036408	histone H3K14 acetyltransferase activity	16/4384	28/18639	0.571428571428571	2.42948383733055	0.000133576534155362	0.00128233472789147
GO:0051019	mitogen-activated protein kinase binding	16/4384	28/18639	0.571428571428571	2.42948383733055	0.000133576534155362	0.00128233472789147
GO:0005484	SNAP receptor activity	19/4384	36/18639	0.527777777777778	2.24389826642336	0.000135467679160748	0.00129092729553184
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	14/4384	23/18639	0.608695652173913	2.58792843541733	0.000139727329995078	0.00130327621476421
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	14/4384	23/18639	0.608695652173913	2.58792843541733	0.000139727329995078	0.00130327621476421
GO:0005525	GTP binding	120/4384	378/18639	0.317460317460317	1.34971324296142	0.000139780396490915	0.00130327621476421
GO:0035173	histone kinase activity	115/4384	360/18639	0.319444444444444	1.35814895072993	0.000144012179566842	0.00133314131941876
GO:0140996	histone H3 kinase activity	114/4384	357/18639	0.319327731092437	1.3576527326259	0.000156045756023312	0.00143429290642704
GO:0004402	histone acetyltransferase activity	21/4384	42/18639	0.5	2.12579835766423	0.000167156896920757	0.00152560097471339
GO:0141003	histone H2AX kinase activity	113/4384	354/18639	0.319209039548023	1.35714810404553	0.000169084079617127	0.00153239837191467
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	23/4384	48/18639	0.479166666666667	2.03722342609489	0.00018841744430729	0.00169575699876561
GO:0017069	snRNA binding	25/4384	54/18639	0.462962962962963	1.96833181265207	0.000199855974764183	0.0017862989192716
GO:0005085	guanyl-nucleotide exchange factor activity	78/4384	230/18639	0.339130434782609	1.44184584258965	0.000211702017618631	0.0018712458124147
GO:0042826	histone deacetylase binding	48/4384	127/18639	0.377952755905512	1.60690269555722	0.000212361797548211	0.0018712458124147
GO:0004518	nuclease activity	72/4384	209/18639	0.344497607655502	1.46466489714665	0.000213691651417728	0.0018712458124147
GO:0010484	histone H3 acetyltransferase activity	16/4384	29/18639	0.551724137931034	2.34570853259502	0.000233069849788483	0.00197964140745159
GO:0043047	single-stranded telomeric DNA binding	9/4384	12/18639	0.75	3.18869753649635	0.000236762668329473	0.00197964140745159
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	9/4384	12/18639	0.75	3.18869753649635	0.000236762668329473	0.00197964140745159
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	9/4384	12/18639	0.75	3.18869753649635	0.000236762668329473	0.00197964140745159
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	9/4384	12/18639	0.75	3.18869753649635	0.000236762668329473	0.00197964140745159
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	9/4384	12/18639	0.75	3.18869753649635	0.000236762668329473	0.00197964140745159
GO:1990247	N6-methyladenosine-containing RNA reader activity	9/4384	12/18639	0.75	3.18869753649635	0.000236762668329473	0.00197964140745159
GO:0004540	RNA nuclease activity	46/4384	121/18639	0.380165289256198	1.61630949508355	0.0002435691666057	0.0020234976918012
GO:0045322	unmethylated CpG binding	8/4384	10/18639	0.8	3.40127737226277	0.000262809024275369	0.00214499555261345
GO:0140033	acetylation-dependent protein binding	14/4384	24/18639	0.583333333333333	2.48009808394161	0.000262812745017518	0.00214499555261345
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	48/4384	128/18639	0.375	1.59434876824818	0.000263159176593779	0.00214499555261345
GO:0008173	RNA methyltransferase activity	29/4384	67/18639	0.432835820895522	1.8402433543959	0.000274069328835628	0.00219414487087371
GO:0030515	snoRNA binding	17/4384	32/18639	0.53125	2.25866075501825	0.000274268108859214	0.00219414487087371
GO:0140142	nucleocytoplasmic carrier activity	17/4384	32/18639	0.53125	2.25866075501825	0.000274268108859214	0.00219414487087371
GO:0061631	ubiquitin conjugating enzyme activity	18/4384	35/18639	0.514285714285714	2.1865354535975	0.000309864030187974	0.00246370419094242
GO:0001671	ATPase activator activity	15/4384	27/18639	0.555555555555556	2.36199817518248	0.000330350160550943	0.00261057200045135
GO:0003684	damaged DNA binding	31/4384	74/18639	0.418918918918919	1.78107429966463	0.00034717658659034	0.00272691428012777
GO:0000287	magnesium ion binding	77/4384	230/18639	0.334782608695652	1.42336063947953	0.000362479036476723	0.00282995681490261
GO:1990841	promoter-specific chromatin binding	29/4384	68/18639	0.426470588235294	1.81318095212538	0.000371499286227777	0.00288301242485748
GO:0035925	mRNA 3'-UTR AU-rich region binding	16/4384	30/18639	0.533333333333333	2.26751824817518	0.000390790469409889	0.00300612741028867
GO:0061733	protein-lysine-acetyltransferase activity	22/4384	47/18639	0.468085106382979	1.99010910079205	0.00039200272557005	0.00300612741028867
GO:0019903	protein phosphatase binding	52/4384	144/18639	0.361111111111111	1.53529881386861	0.00043646675674612	0.0033274171573116
GO:0004721	phosphoprotein phosphatase activity	61/4384	175/18639	0.348571428571429	1.48198514077164	0.000439488911181881	0.00333086332685215
GO:0042809	nuclear vitamin D receptor binding	10/4384	15/18639	0.666666666666667	2.83439781021898	0.000467691472828822	0.00350833022527626
GO:0017056	structural constituent of nuclear pore	14/4384	25/18639	0.56	2.38089416058394	0.00046831877235555	0.00350833022527626
GO:0000339	RNA cap binding	12/4384	20/18639	0.6	2.55095802919708	0.000512861133744499	0.00381993120306248
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	33/4384	82/18639	0.402439024390244	1.71100843421755	0.000545153172248462	0.00402263396055735
GO:0008017	microtubule binding	89/4384	276/18639	0.322463768115942	1.37098589733418	0.00054628362427322	0.00402263396055735
GO:0004535	poly(A)-specific ribonuclease activity	9/4384	13/18639	0.692307692307692	2.94341311061202	0.000608196545385797	0.00440347889843572
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	9/4384	13/18639	0.692307692307692	2.94341311061202	0.000608196545385797	0.00440347889843572
GO:0140852	histone ubiquitin ligase activity	9/4384	13/18639	0.692307692307692	2.94341311061202	0.000608196545385797	0.00440347889843572
GO:0035591	signaling adaptor activity	47/4384	129/18639	0.364341085271318	1.54903136139874	0.000640665916527517	0.00461279459899813
GO:0070577	lysine-acetylated histone binding	13/4384	23/18639	0.565217391304348	2.40307640431609	0.000663945606375251	0.0047539972699576
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	33/4384	83/18639	0.397590361445783	1.69039387476915	0.000703060115838187	0.005006406099595
GO:0004722	protein serine/threonine phosphatase activity	39/4384	103/18639	0.378640776699029	1.60982788250301	0.000762804752194421	0.00537967603369071
GO:0032404	mismatch repair complex binding	8/4384	11/18639	0.727272727272727	3.0920703384207	0.000763781165277076	0.00537967603369071
GO:0030331	nuclear estrogen receptor binding	19/4384	40/18639	0.475	2.01950843978102	0.000768898763220121	0.00538644755207176
GO:0016763	pentosyltransferase activity	22/4384	49/18639	0.448979591836735	1.90888015790258	0.000798660287858529	0.00556485877991749
GO:0106222	lncRNA binding	15/4384	29/18639	0.517241379310345	2.19910174930783	0.000904889655500163	0.00627132082100647
GO:0035613	RNA stem-loop binding	12/4384	21/18639	0.571428571428571	2.42948383733055	0.000941149794560985	0.0063194072082228
GO:0033192	calmodulin-dependent protein phosphatase activity	32/4384	81/18639	0.395061728395062	1.67964314679643	0.000955712818527522	0.0063194072082228
GO:0140791	histone H2AXS140 phosphatase activity	32/4384	81/18639	0.395061728395062	1.67964314679643	0.000955712818527522	0.0063194072082228
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	32/4384	81/18639	0.395061728395062	1.67964314679643	0.000955712818527522	0.0063194072082228
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	32/4384	81/18639	0.395061728395062	1.67964314679643	0.000955712818527522	0.0063194072082228
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	32/4384	81/18639	0.395061728395062	1.67964314679643	0.000955712818527522	0.0063194072082228
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	32/4384	81/18639	0.395061728395062	1.67964314679643	0.000955712818527522	0.0063194072082228
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	32/4384	81/18639	0.395061728395062	1.67964314679643	0.000955712818527522	0.0063194072082228
GO:1990439	MAP kinase serine/threonine phosphatase activity	32/4384	81/18639	0.395061728395062	1.67964314679643	0.000955712818527522	0.0063194072082228
GO:0008234	cysteine-type peptidase activity	63/4384	187/18639	0.336898395721925	1.43235611265077	0.000984314732526516	0.0064754918444384
GO:0019001	guanyl nucleotide binding	121/4384	400/18639	0.3025	1.28610800638686	0.00106931301204361	0.00696396815883679
GO:0032561	guanyl ribonucleotide binding	121/4384	400/18639	0.3025	1.28610800638686	0.00106931301204361	0.00696396815883679
GO:0034212	protein N-acetyltransferase activity	23/4384	53/18639	0.433962264150943	1.84503253684066	0.00109085987491076	0.0070687719894217
GO:0001784	phosphotyrosine residue binding	21/4384	47/18639	0.446808510638298	1.89964959621059	0.00112607125713107	0.00722469479822706
GO:1990518	single-stranded 3'-5' DNA helicase activity	21/4384	47/18639	0.446808510638298	1.89964959621059	0.00112607125713107	0.00722469479822706
GO:0101005	deubiquitinase activity	42/4384	115/18639	0.365217391304348	1.5527570612504	0.00114315913059737	0.0072981981933704
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	44/4384	122/18639	0.360655737704918	1.53336274979059	0.00118935903240921	0.00755592797059969
GO:0033549	MAP kinase phosphatase activity	32/4384	82/18639	0.390243902439024	1.65915969378672	0.00121847099214612	0.00770311417473842
GO:0140036	ubiquitin-modified protein reader activity	11/4384	19/18639	0.578947368421053	2.46145072992701	0.00133345065102874	0.00838908759093809
GO:0098847	sequence-specific single stranded DNA binding	9/4384	14/18639	0.642857142857143	2.73316931699687	0.00134708792695012	0.0084339418035138
GO:0031624	ubiquitin conjugating enzyme binding	15/4384	30/18639	0.5	2.12579835766423	0.00141898884159044	0.00875718827952959
GO:0032452	histone demethylase activity	15/4384	30/18639	0.5	2.12579835766423	0.00141898884159044	0.00875718827952959
GO:0070566	adenylyltransferase activity	15/4384	30/18639	0.5	2.12579835766423	0.00141898884159044	0.00875718827952959
GO:0016407	acetyltransferase activity	36/4384	96/18639	0.375	1.59434876824818	0.00145698742800843	0.00894907917866791
GO:0044390	ubiquitin-like protein conjugating enzyme binding	17/4384	36/18639	0.472222222222222	2.00769844890511	0.00156152299175943	0.00942179927695113
GO:0036121	double-stranded DNA helicase activity	21/4384	48/18639	0.4375	1.8600735629562	0.00156302997264236	0.00942179927695113
GO:0043138	3'-5' DNA helicase activity	21/4384	48/18639	0.4375	1.8600735629562	0.00156302997264236	0.00942179927695113
GO:0140693	molecular condensate scaffold activity	21/4384	48/18639	0.4375	1.8600735629562	0.00156302997264236	0.00942179927695113
GO:0004407	histone deacetylase activity	12/4384	22/18639	0.545454545454545	2.31905275381553	0.00162935156436346	0.00968642030924334
GO:0033558	protein lysine deacetylase activity	12/4384	22/18639	0.545454545454545	2.31905275381553	0.00162935156436346	0.00968642030924334
GO:0140035	ubiquitin-like protein reader activity	12/4384	22/18639	0.545454545454545	2.31905275381553	0.00162935156436346	0.00968642030924334
GO:0000340	RNA 7-methylguanosine cap binding	8/4384	12/18639	0.666666666666667	2.83439781021898	0.00181781815917229	0.0106121276319247
GO:0016273	arginine N-methyltransferase activity	8/4384	12/18639	0.666666666666667	2.83439781021898	0.00181781815917229	0.0106121276319247
GO:0016274	protein-arginine N-methyltransferase activity	8/4384	12/18639	0.666666666666667	2.83439781021898	0.00181781815917229	0.0106121276319247
GO:1990817	poly(A) RNA polymerase activity	8/4384	12/18639	0.666666666666667	2.83439781021898	0.00181781815917229	0.0106121276319247
GO:0004659	prenyltransferase activity	10/4384	17/18639	0.588235294117647	2.50093924431086	0.00188734863906098	0.0108669554240019
GO:0032183	SUMO binding	10/4384	17/18639	0.588235294117647	2.50093924431086	0.00188734863906098	0.0108669554240019
GO:0070403	NAD+ binding	10/4384	17/18639	0.588235294117647	2.50093924431086	0.00188734863906098	0.0108669554240019
GO:0017116	single-stranded DNA helicase activity	24/4384	58/18639	0.413793103448276	1.75928139944626	0.00190339419849416	0.0108669554240019
GO:0061980	regulatory RNA binding	24/4384	58/18639	0.413793103448276	1.75928139944626	0.00190339419849416	0.0108669554240019
GO:0017018	myosin phosphatase activity	32/4384	84/18639	0.380952380952381	1.6196558915537	0.00193699097971787	0.011010264516291
GO:0003924	GTPase activity	101/4384	331/18639	0.305135951661631	1.29731500981322	0.00194767821385688	0.0110226679701245
GO:0019789	SUMO transferase activity	14/4384	28/18639	0.5	2.12579835766423	0.00203730335231307	0.0114300655610292
GO:0141052	histone H3 demethylase activity	14/4384	28/18639	0.5	2.12579835766423	0.00203730335231307	0.0114300655610292
GO:0030145	manganese ion binding	27/4384	68/18639	0.397058823529412	1.68813398990983	0.00211642575027467	0.0117720505251329
GO:0140223	general transcription initiation factor activity	27/4384	68/18639	0.397058823529412	1.68813398990983	0.00211642575027467	0.0117720505251329
GO:0140457	protein demethylase activity	15/4384	31/18639	0.483870967741935	2.05722421709442	0.00215661301637739	0.0119443182445517
GO:0140789	histone phosphatase activity	47/4384	136/18639	0.345588235294118	1.46930180603263	0.00228455280843137	0.0125990657009662
GO:0140939	histone H4 methyltransferase activity	11/4384	20/18639	0.55	2.33837819343066	0.00233639339437614	0.0128261280771864
GO:0019003	GDP binding	29/4384	75/18639	0.386666666666667	1.64395072992701	0.00237726134780583	0.0128261280771864
GO:0016427	tRNA (cytidine) methyltransferase activity	7/4384	10/18639	0.7	2.97611770072993	0.00239500231070918	0.0128261280771864
GO:0031996	thioesterase binding	7/4384	10/18639	0.7	2.97611770072993	0.00239500231070918	0.0128261280771864
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	7/4384	10/18639	0.7	2.97611770072993	0.00239500231070918	0.0128261280771864
GO:0098505	G-rich strand telomeric DNA binding	7/4384	10/18639	0.7	2.97611770072993	0.00239500231070918	0.0128261280771864
GO:0099122	RNA polymerase II C-terminal domain binding	7/4384	10/18639	0.7	2.97611770072993	0.00239500231070918	0.0128261280771864
GO:0036002	pre-mRNA binding	24/4384	59/18639	0.406779661016949	1.72946307064209	0.00250267804936451	0.0133476162632774
GO:0061578	K63-linked deubiquitinase activity	9/4384	15/18639	0.6	2.55095802919708	0.00266618260813207	0.0141613633612261
GO:0044013	histone H2B acetyltransferase activity	12/4384	23/18639	0.521739130434783	2.21822437321485	0.00268252170035059	0.0141899923414464
GO:0008080	N-acetyltransferase activity	27/4384	69/18639	0.391304347826087	1.66366827991114	0.00270902343628123	0.0142719283472377
GO:0061749	forked DNA-dependent helicase activity	20/4384	47/18639	0.425531914893617	1.80919009162914	0.00298765155932764	0.0156424149816243
GO:0051536	iron-sulfur cluster binding	29/4384	76/18639	0.381578947368421	1.62231979927007	0.00299330163228613	0.0156424149816243
GO:0019208	phosphatase regulator activity	41/4384	117/18639	0.35042735042735	1.48987577203818	0.00315421161645003	0.0164171014253785
GO:0019888	protein phosphatase regulator activity	38/4384	107/18639	0.355140186915888	1.50991285217273	0.0033671160582611	0.0174551296460255
GO:0019210	kinase inhibitor activity	33/4384	90/18639	0.366666666666667	1.55891879562044	0.00341076569160328	0.017610965483338
GO:0016791	phosphatase activity	84/4384	273/18639	0.307692307692308	1.30818360471645	0.0034463086796331	0.0177238732095416
GO:0051540	metal cluster binding	29/4384	77/18639	0.376623376623377	1.60125071096786	0.003739864269773	0.0191575655874538
GO:0051010	microtubule plus-end binding	11/4384	21/18639	0.523809523809524	2.22702685088634	0.00387116135417281	0.0197520673819211
GO:0004860	protein kinase inhibitor activity	31/4384	84/18639	0.369047619047619	1.56904164494265	0.00398027748138812	0.0202291749642314
GO:0009378	four-way junction helicase activity	20/4384	48/18639	0.416666666666667	1.77149863138686	0.00400523840695997	0.0202765194352348
GO:0043998	histone H2A acetyltransferase activity	12/4384	24/18639	0.5	2.12579835766423	0.00422703168544863	0.021316081962418
GO:0035198	miRNA binding	18/4384	42/18639	0.428571428571429	1.82211287799791	0.00432898997406579	0.0216616641173331
GO:0051879	Hsp90 protein binding	18/4384	42/18639	0.428571428571429	1.82211287799791	0.00432898997406579	0.0216616641173331
GO:0004197	cysteine-type endopeptidase activity	32/4384	88/18639	0.363636363636364	1.54603516921035	0.00450713506754118	0.0224663347982052
GO:0005521	lamin binding	9/4384	16/18639	0.5625	2.39152315237226	0.00482880458348205	0.0239775124145316
GO:0042578	phosphoric ester hydrolase activity	107/4384	363/18639	0.294765840220386	1.25322547807203	0.00488699477985013	0.0241738367736098
GO:0070990	snRNP binding	7/4384	11/18639	0.636363636363636	2.70556154611812	0.00524963931521538	0.0258689450666127
GO:0061791	GTPase motor activity	17/4384	40/18639	0.425	1.8069286040146	0.00607607738792925	0.0280936546191521
GO:1990606	membrane scission GTPase motor activity	17/4384	40/18639	0.425	1.8069286040146	0.00607607738792925	0.0280936546191521
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0032931	histone H3K56 acetyltransferase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0034062	5'-3' RNA polymerase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0043992	histone H3K9 acetyltransferase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0043993	histone H3K18 acetyltransferase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0043994	histone H3K23 acetyltransferase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0043999	histone H2AK5 acetyltransferase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0044012	histone H2AK9 acetyltransferase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0044014	histone H2BK5 acetyltransferase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0044015	histone H2BK12 acetyltransferase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0044016	histone H3K4 acetyltransferase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0044017	histone H3K27 acetyltransferase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0044018	histone H3K36 acetyltransferase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0046972	histone H4K16 acetyltransferase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0070034	telomerase RNA binding	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0097747	RNA polymerase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0140908	histone H3K122 acetyltransferase activity	11/4384	22/18639	0.5	2.12579835766423	0.00611297114398216	0.0280936546191521
GO:0008139	nuclear localization sequence binding	12/4384	25/18639	0.48	2.04076642335766	0.00640874179196334	0.0293488670048922
GO:0008175	tRNA methyltransferase activity	15/4384	34/18639	0.441176470588235	1.87570443323315	0.00644685647238839	0.0294194577049836
GO:0005164	tumor necrosis factor receptor binding	14/4384	31/18639	0.451612903225806	1.92007593595479	0.00653935563811023	0.0297368593227749
GO:0043539	protein serine/threonine kinase activator activity	27/4384	73/18639	0.36986301369863	1.57250837416258	0.0066750489452618	0.0302477742414661
GO:0008174	mRNA methyltransferase activity	8/4384	14/18639	0.571428571428571	2.42948383733055	0.00696137916027138	0.0312178110439852
GO:0030983	mismatched DNA binding	8/4384	14/18639	0.571428571428571	2.42948383733055	0.00696137916027138	0.0312178110439852
GO:0070742	C2H2 zinc finger domain binding	8/4384	14/18639	0.571428571428571	2.42948383733055	0.00696137916027138	0.0312178110439852
GO:0017124	SH3 domain binding	39/4384	115/18639	0.339130434782609	1.44184584258965	0.00731064378932845	0.0326710150033437
GO:0004843	cysteine-type deubiquitinase activity	37/4384	108/18639	0.342592592592593	1.45656554136253	0.00736237501483703	0.0327891340866969
GO:0043014	alpha-tubulin binding	18/4384	44/18639	0.409090909090909	1.73928956536165	0.00773739118601002	0.0343412978666746
GO:0051787	misfolded protein binding	9/4384	17/18639	0.529411764705882	2.25084531987978	0.00813794252095573	0.0359958140176062
GO:0019209	kinase activator activity	48/4384	148/18639	0.324324324324324	1.37889623199842	0.00825610126047703	0.0363942422910824
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	10/4384	20/18639	0.5	2.12579835766423	0.00886950831057506	0.0387033089916003
GO:0043024	ribosomal small subunit binding	10/4384	20/18639	0.5	2.12579835766423	0.00886950831057506	0.0387033089916003
GO:0061608	nuclear import signal receptor activity	10/4384	20/18639	0.5	2.12579835766423	0.00886950831057506	0.0387033089916003
GO:0070717	poly-purine tract binding	14/4384	32/18639	0.4375	1.8600735629562	0.00914761508528723	0.0397829166125243
GO:0050681	nuclear androgen receptor binding	12/4384	26/18639	0.461538461538462	1.96227540707468	0.00938959293098529	0.0406987038078827
GO:0000995	RNA polymerase III general transcription initiation factor activity	7/4384	12/18639	0.583333333333333	2.48009808394161	0.0100541889336757	0.043004055637108
GO:0005049	nuclear export signal receptor activity	7/4384	12/18639	0.583333333333333	2.48009808394161	0.0100541889336757	0.043004055637108
GO:0005095	GTPase inhibitor activity	7/4384	12/18639	0.583333333333333	2.48009808394161	0.0100541889336757	0.043004055637108
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	7/4384	12/18639	0.583333333333333	2.48009808394161	0.0100541889336757	0.043004055637108
GO:0051539	4 iron, 4 sulfur cluster binding	18/4384	45/18639	0.4	1.70063868613139	0.0101116277543307	0.043107465689515
GO:0019843	rRNA binding	24/4384	65/18639	0.369230769230769	1.56982032565974	0.0104160798764901	0.0441151618298403
GO:0160215	deacylase activity	24/4384	65/18639	0.369230769230769	1.56982032565974	0.0104160798764901	0.0441151618298403
GO:0031386	protein tag activity	8/4384	15/18639	0.533333333333333	2.26751824817518	0.0118701752198592	0.0496249905965726
GO:0141047	molecular tag activity	8/4384	15/18639	0.533333333333333	2.26751824817518	0.0118701752198592	0.0496249905965726
GO:0141050	histone H3K deacetylase activity	8/4384	15/18639	0.533333333333333	2.26751824817518	0.0118701752198592	0.0496249905965726
GO:0141051	histone H4K deacetylase activity	8/4384	15/18639	0.533333333333333	2.26751824817518	0.0118701752198592	0.0496249905965726
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	69/4384	229/18639	0.301310043668122	1.28104879195487	0.0123908962244546	0.0516353746202352
GO:0140311	protein sequestering activity	14/4384	33/18639	0.424242424242424	1.80370769741208	0.0125087759160518	0.0519595307282151
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	9/4384	18/18639	0.5	2.12579835766423	0.0129200395586185	0.0534963938273786
GO:0008187	poly-pyrimidine tract binding	13/4384	30/18639	0.433333333333333	1.84235857664234	0.0129866944199292	0.053601133656778
GO:0000049	tRNA binding	28/4384	80/18639	0.35	1.48805885036496	0.0133571237708509	0.0548386254747726
GO:0009931	calcium-dependent protein serine/threonine kinase activity	10/4384	21/18639	0.476190476190476	2.02456986444213	0.0134134600891226	0.0548386254747726
GO:0070182	DNA polymerase binding	10/4384	21/18639	0.476190476190476	2.02456986444213	0.0134134600891226	0.0548386254747726
GO:0035035	histone acetyltransferase binding	11/4384	24/18639	0.458333333333333	1.94864849452555	0.013514142051964	0.0549038498412078
GO:0048027	mRNA 5'-UTR binding	11/4384	24/18639	0.458333333333333	1.94864849452555	0.013514142051964	0.0549038498412078
GO:0008641	ubiquitin-like modifier activating enzyme activity	6/4384	10/18639	0.6	2.55095802919708	0.0145418805101029	0.0581675220404117
GO:0030957	Tat protein binding	6/4384	10/18639	0.6	2.55095802919708	0.0145418805101029	0.0581675220404117
GO:0043422	protein kinase B binding	6/4384	10/18639	0.6	2.55095802919708	0.0145418805101029	0.0581675220404117
GO:0050815	phosphoserine residue binding	6/4384	10/18639	0.6	2.55095802919708	0.0145418805101029	0.0581675220404117
GO:0051864	histone H3K36 demethylase activity	6/4384	10/18639	0.6	2.55095802919708	0.0145418805101029	0.0581675220404117
GO:0032451	demethylase activity	16/4384	40/18639	0.4	1.70063868613139	0.0148750037296193	0.0593169379494972
GO:0032813	tumor necrosis factor receptor superfamily binding	19/4384	50/18639	0.38	1.61560675182482	0.015373167299179	0.0611154135574722
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	14/4384	34/18639	0.411764705882353	1.7506574710176	0.0167521195266162	0.0661913015441908
GO:0030332	cyclin binding	14/4384	34/18639	0.411764705882353	1.7506574710176	0.0167521195266162	0.0661913015441908
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	7/4384	13/18639	0.538461538461538	2.28932130825379	0.0174053278248616	0.0683554692758201
GO:0046974	histone H3K9 methyltransferase activity	7/4384	13/18639	0.538461538461538	2.28932130825379	0.0174053278248616	0.0683554692758201
GO:0003925	G protein activity	20/4384	54/18639	0.37037037037037	1.57466545012165	0.0177305846109748	0.0694224702592849
GO:0001046	core promoter sequence-specific DNA binding	17/4384	44/18639	0.386363636363636	1.642662367286	0.0178470612084334	0.0696680461630412
GO:0051537	2 iron, 2 sulfur cluster binding	12/4384	28/18639	0.428571428571429	1.82211287799791	0.01844673141716	0.0717926844343525
GO:0004708	MAP kinase kinase activity	8/4384	16/18639	0.5	2.12579835766423	0.0189115458562363	0.0733813276337793
GO:0050321	tau-protein kinase activity	10/4384	22/18639	0.454545454545455	1.93254396151294	0.0194972008767397	0.0752351890917097
GO:0042800	histone H3K4 methyltransferase activity	9/4384	19/18639	0.473684210526316	2.01391423357664	0.019505419394147	0.0752351890917097
GO:0140313	molecular sequestering activity	20/4384	55/18639	0.363636363636364	1.54603516921035	0.0218482748812937	0.0840218523624825
GO:0004715	non-membrane spanning protein tyrosine kinase activity	17/4384	45/18639	0.377777777777778	1.60615875912409	0.0225435743769957	0.0861842843439126
GO:0140303	intramembrane lipid transporter activity	17/4384	45/18639	0.377777777777778	1.60615875912409	0.0225435743769957	0.0861842843439126
GO:0016410	N-acyltransferase activity	31/4384	94/18639	0.329787234042553	1.40212232101258	0.0232978255143419	0.088805829019374
GO:0003735	structural constituent of ribosome	53/4384	175/18639	0.302857142857143	1.28762643378519	0.0233680596542906	0.0888123322931398
GO:0031593	polyubiquitin modification-dependent protein binding	21/4384	59/18639	0.355932203389831	1.51328018681183	0.0244379055000536	0.0926067997896768
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	6/4384	11/18639	0.545454545454545	2.31905275381553	0.025692569943968	0.0962357533161344
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	6/4384	11/18639	0.545454545454545	2.31905275381553	0.025692569943968	0.0962357533161344
GO:0140031	phosphorylation-dependent protein binding	6/4384	11/18639	0.545454545454545	2.31905275381553	0.025692569943968	0.0962357533161344
GO:0140537	transcription regulator activator activity	6/4384	11/18639	0.545454545454545	2.31905275381553	0.025692569943968	0.0962357533161344
GO:0030295	protein kinase activator activity	43/4384	139/18639	0.309352517985612	1.31524214934622	0.0270692345994281	0.101100080809391
GO:0000149	SNARE binding	34/4384	106/18639	0.320754716981132	1.36371970114309	0.0274417045023044	0.102196692629272
GO:0061665	SUMO ligase activity	7/4384	14/18639	0.5	2.12579835766423	0.0278492764894517	0.10341737057401
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	8/4384	17/18639	0.470588235294118	2.00075139544869	0.0284880821542635	0.104887938840697
GO:0005092	GDP-dissociation inhibitor activity	8/4384	17/18639	0.470588235294118	2.00075139544869	0.0284880821542635	0.104887938840697
GO:1990226	histone methyltransferase binding	8/4384	17/18639	0.470588235294118	2.00075139544869	0.0284880821542635	0.104887938840697
GO:0016251	RNA polymerase II general transcription initiation factor activity	19/4384	53/18639	0.358490566037736	1.52415731304228	0.0290939318537123	0.106815115247624
GO:0004712	protein serine/threonine/tyrosine kinase activity	16/4384	43/18639	0.372093023255814	1.58198947547106	0.030570205493022	0.110981823752041
GO:0048156	tau protein binding	16/4384	43/18639	0.372093023255814	1.58198947547106	0.030570205493022	0.110981823752041
GO:0071889	14-3-3 protein binding	13/4384	33/18639	0.393939393939394	1.67487143331121	0.0305713820057707	0.110981823752041
GO:0140416	transcription regulator inhibitor activity	13/4384	33/18639	0.393939393939394	1.67487143331121	0.0305713820057707	0.110981823752041
GO:0008266	poly(U) RNA binding	11/4384	27/18639	0.407407407407407	1.73213199513382	0.0350658208888951	0.126588590172724
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	11/4384	27/18639	0.407407407407407	1.73213199513382	0.0350658208888951	0.126588590172724
GO:0019213	deacetylase activity	14/4384	37/18639	0.378378378378378	1.60871227066483	0.0360689968534216	0.129848388672318
GO:0001223	transcription coactivator binding	16/4384	44/18639	0.363636363636364	1.54603516921035	0.0378405736556441	0.135848707639099
GO:0035091	phosphatidylinositol binding	80/4384	284/18639	0.28169014084507	1.19763287755731	0.0386274652855988	0.138290593950652
GO:0052866	phosphatidylinositol phosphate phosphatase activity	13/4384	34/18639	0.382352941176471	1.62561050880206	0.0391261635404852	0.139552853003773
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9/4384	21/18639	0.428571428571429	1.82211287799791	0.0393030797425749	0.139552853003773
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	9/4384	21/18639	0.428571428571429	1.82211287799791	0.0393030797425749	0.139552853003773
GO:0004725	protein tyrosine phosphatase activity	31/4384	98/18639	0.316326530612245	1.34489283852227	0.0408200927425434	0.142839766497924
GO:0008409	5'-3' exonuclease activity	8/4384	18/18639	0.444444444444444	1.88959854014599	0.0409425162307795	0.142839766497924
GO:0070628	proteasome binding	8/4384	18/18639	0.444444444444444	1.88959854014599	0.0409425162307795	0.142839766497924
GO:0001727	lipid kinase activity	15/4384	41/18639	0.365853658536585	1.55546221292505	0.0413141738738972	0.142839766497924
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	15/4384	41/18639	0.365853658536585	1.55546221292505	0.0413141738738972	0.142839766497924
GO:0016877	ligase activity, forming carbon-sulfur bonds	15/4384	41/18639	0.365853658536585	1.55546221292505	0.0413141738738972	0.142839766497924
GO:0140318	protein transporter activity	15/4384	41/18639	0.365853658536585	1.55546221292505	0.0413141738738972	0.142839766497924
GO:0035197	siRNA binding	6/4384	12/18639	0.5	2.12579835766423	0.0413309509542603	0.142839766497924
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	6/4384	12/18639	0.5	2.12579835766423	0.0413309509542603	0.142839766497924
GO:0141221	histone deacetylase activity, hydrolytic mechanism	6/4384	12/18639	0.5	2.12579835766423	0.0413309509542603	0.142839766497924
GO:0000774	adenyl-nucleotide exchange factor activity	7/4384	15/18639	0.466666666666667	1.98407846715328	0.0418309901003453	0.143420537486898
GO:0050700	CARD domain binding	7/4384	15/18639	0.466666666666667	1.98407846715328	0.0418309901003453	0.143420537486898
GO:0140776	protein-containing complex destabilizing activity	7/4384	15/18639	0.466666666666667	1.98407846715328	0.0418309901003453	0.143420537486898
GO:0030159	signaling receptor complex adaptor activity	18/4384	52/18639	0.346153846153846	1.47170655530601	0.0464354139115386	0.158787061818876
GO:0043015	gamma-tubulin binding	13/4384	35/18639	0.371428571428571	1.57916449426486	0.0492410834115228	0.167938010792983
GO:0047617	fatty acyl-CoA hydrolase activity	10/4384	25/18639	0.4	1.70063868613139	0.0493914471501402	0.168008702117012
GO:0008649	rRNA methyltransferase activity	9/4384	22/18639	0.409090909090909	1.73928956536165	0.0530148420343071	0.179797913687376
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	28/4384	89/18639	0.314606741573034	1.3375809890921	0.0532734559073708	0.179797913687376
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	28/4384	89/18639	0.314606741573034	1.3375809890921	0.0532734559073708	0.179797913687376
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	20/4384	60/18639	0.333333333333333	1.41719890510949	0.0541313085624307	0.182218638693273
GO:0120227	acyl-CoA binding	8/4384	19/18639	0.421052631578947	1.79014598540146	0.0565331321119669	0.189810723360386
GO:0000062	fatty-acyl-CoA binding	7/4384	16/18639	0.4375	1.8600735629562	0.05965722451243	0.197738524215113
GO:0003688	DNA replication origin binding	7/4384	16/18639	0.4375	1.8600735629562	0.05965722451243	0.197738524215113
GO:0017070	U6 snRNA binding	7/4384	16/18639	0.4375	1.8600735629562	0.05965722451243	0.197738524215113
GO:0034450	ubiquitin-ubiquitin ligase activity	7/4384	16/18639	0.4375	1.8600735629562	0.05965722451243	0.197738524215113
GO:0043023	ribosomal large subunit binding	7/4384	16/18639	0.4375	1.8600735629562	0.05965722451243	0.197738524215113
GO:0140793	histone H2AXY142 phosphatase activity	28/4384	90/18639	0.311111111111111	1.32271897810219	0.0605407182187408	0.199316382174515
GO:1901981	phosphatidylinositol phosphate binding	53/4384	185/18639	0.286486486486487	1.21802500493194	0.0610096668997349	0.199316382174515
GO:0051011	microtubule minus-end binding	6/4384	13/18639	0.461538461538462	1.96227540707468	0.0618386279223163	0.199316382174515
GO:0097157	pre-mRNA intronic binding	6/4384	13/18639	0.461538461538462	1.96227540707468	0.0618386279223163	0.199316382174515
GO:0140666	annealing activity	6/4384	13/18639	0.461538461538462	1.96227540707468	0.0618386279223163	0.199316382174515
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	5/4384	10/18639	0.5	2.12579835766423	0.0619787824200075	0.199316382174515
GO:0016303	1-phosphatidylinositol-3-kinase activity	5/4384	10/18639	0.5	2.12579835766423	0.0619787824200075	0.199316382174515
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	5/4384	10/18639	0.5	2.12579835766423	0.0619787824200075	0.199316382174515
GO:0042975	peroxisome proliferator activated receptor binding	5/4384	10/18639	0.5	2.12579835766423	0.0619787824200075	0.199316382174515
GO:0051880	G-quadruplex DNA binding	5/4384	10/18639	0.5	2.12579835766423	0.0619787824200075	0.199316382174515
GO:0140999	histone H3K4 trimethyltransferase activity	5/4384	10/18639	0.5	2.12579835766423	0.0619787824200075	0.199316382174515
GO:1905394	retromer complex binding	5/4384	10/18639	0.5	2.12579835766423	0.0619787824200075	0.199316382174515
GO:0016289	acyl-CoA hydrolase activity	10/4384	26/18639	0.384615384615385	1.63522950589556	0.0638762954585514	0.204404145467365
GO:0070412	R-SMAD binding	10/4384	26/18639	0.384615384615385	1.63522950589556	0.0638762954585514	0.204404145467365
GO:0051287	NAD binding	18/4384	54/18639	0.333333333333333	1.41719890510949	0.0653995325620315	0.208763039902446
GO:0019239	deaminase activity	12/4384	33/18639	0.363636363636364	1.54603516921035	0.0669781215379986	0.213276770302816
GO:0003887	DNA-directed DNA polymerase activity	9/4384	23/18639	0.391304347826087	1.66366827991114	0.0694983333452237	0.219148029234574
GO:0042171	lysophosphatidic acid acyltransferase activity	9/4384	23/18639	0.391304347826087	1.66366827991114	0.0694983333452237	0.219148029234574
GO:0071617	lysophospholipid acyltransferase activity	9/4384	23/18639	0.391304347826087	1.66366827991114	0.0694983333452237	0.219148029234574
GO:0140102	catalytic activity, acting on a rRNA	9/4384	23/18639	0.391304347826087	1.66366827991114	0.0694983333452237	0.219148029234574
GO:0016790	thiolester hydrolase activity	15/4384	44/18639	0.340909090909091	1.4494079711347	0.0737610732995575	0.232025123777249
GO:0016004	phospholipase activator activity	8/4384	20/18639	0.4	1.70063868613139	0.0754168678782621	0.236087586401516
GO:0052745	inositol phosphate phosphatase activity	8/4384	20/18639	0.4	1.70063868613139	0.0754168678782621	0.236087586401516
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	10/4384	27/18639	0.37037037037037	1.57466545012165	0.0808236334407021	0.252403443226867
GO:0042287	MHC protein binding	14/4384	41/18639	0.341463414634146	1.45176473206338	0.0813463576508009	0.252613418457986
GO:0045125	bioactive lipid receptor activity	7/4384	17/18639	0.411764705882353	1.7506574710176	0.0814756241631467	0.252613418457986
GO:1901567	fatty acid derivative binding	7/4384	17/18639	0.411764705882353	1.7506574710176	0.0814756241631467	0.252613418457986
GO:0008474	palmitoyl-(protein) hydrolase activity	6/4384	14/18639	0.428571428571429	1.82211287799791	0.0873306414969646	0.266935168349213
GO:0032454	histone H3K9 demethylase activity	6/4384	14/18639	0.428571428571429	1.82211287799791	0.0873306414969646	0.266935168349213
GO:0034236	protein kinase A catalytic subunit binding	6/4384	14/18639	0.428571428571429	1.82211287799791	0.0873306414969646	0.266935168349213
GO:0042043	neurexin family protein binding	6/4384	14/18639	0.428571428571429	1.82211287799791	0.0873306414969646	0.266935168349213
GO:0071933	Arp2/3 complex binding	6/4384	14/18639	0.428571428571429	1.82211287799791	0.0873306414969646	0.266935168349213
GO:0098599	palmitoyl hydrolase activity	6/4384	14/18639	0.428571428571429	1.82211287799791	0.0873306414969646	0.266935168349213
GO:0140101	catalytic activity, acting on a tRNA	40/4384	139/18639	0.287769784172662	1.22348106915927	0.0879980447386709	0.268342272897218
GO:0001091	RNA polymerase II general transcription initiation factor binding	9/4384	24/18639	0.375	1.59434876824818	0.0888331428082359	0.269620030631086
GO:0060229	lipase activator activity	9/4384	24/18639	0.375	1.59434876824818	0.0888331428082359	0.269620030631086
GO:0004143	ATP-dependent diacylglycerol kinase activity	5/4384	11/18639	0.454545454545455	1.93254396151294	0.0922172928167073	0.274743934460811
GO:0015173	aromatic amino acid transmembrane transporter activity	5/4384	11/18639	0.454545454545455	1.93254396151294	0.0922172928167073	0.274743934460811
GO:0019107	myristoyltransferase activity	5/4384	11/18639	0.454545454545455	1.93254396151294	0.0922172928167073	0.274743934460811
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	5/4384	11/18639	0.454545454545455	1.93254396151294	0.0922172928167073	0.274743934460811
GO:0032794	GTPase activating protein binding	5/4384	11/18639	0.454545454545455	1.93254396151294	0.0922172928167073	0.274743934460811
GO:0034511	U3 snoRNA binding	5/4384	11/18639	0.454545454545455	1.93254396151294	0.0922172928167073	0.274743934460811
GO:0042608	T cell receptor binding	5/4384	11/18639	0.454545454545455	1.93254396151294	0.0922172928167073	0.274743934460811
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	5/4384	11/18639	0.454545454545455	1.93254396151294	0.0922172928167073	0.274743934460811
GO:0004520	DNA endonuclease activity	14/4384	42/18639	0.333333333333333	1.41719890510949	0.0966592383578068	0.286659892246493
GO:0048487	beta-tubulin binding	14/4384	42/18639	0.333333333333333	1.41719890510949	0.0966592383578068	0.286659892246493
GO:0004536	DNA nuclease activity	20/4384	64/18639	0.3125	1.32862397354015	0.097184349696182	0.287559171703771
GO:0072542	protein phosphatase activator activity	8/4384	21/18639	0.380952380952381	1.6196558915537	0.0976407375002233	0.288159338966336
GO:0046332	SMAD binding	24/4384	79/18639	0.30379746835443	1.2916243185808	0.0978318743404228	0.288159338966336
GO:0005154	epidermal growth factor receptor binding	12/4384	35/18639	0.342857142857143	1.45769030239833	0.0993504543924357	0.291308119666508
GO:0034061	DNA polymerase activity	12/4384	35/18639	0.342857142857143	1.45769030239833	0.0993504543924357	0.291308119666508
GO:0097718	disordered domain specific binding	10/4384	28/18639	0.357142857142857	1.5184273983316	0.100270457924089	0.293342016861442
GO:0005548	phospholipid transporter activity	21/4384	68/18639	0.308823529411765	1.3129931032632	0.100760146018604	0.294110696486737
GO:0003746	translation elongation factor activity	7/4384	18/18639	0.388888888888889	1.65339872262774	0.107269420120108	0.311706655775021
GO:0017128	phospholipid scramblase activity	7/4384	18/18639	0.388888888888889	1.65339872262774	0.107269420120108	0.311706655775021
GO:0031369	translation initiation factor binding	11/4384	32/18639	0.34375	1.46148637089416	0.110070114178934	0.319129458559058
GO:0042974	nuclear retinoic acid receptor binding	9/4384	25/18639	0.36	1.53057481751825	0.111019096615915	0.320447102927006
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	9/4384	25/18639	0.36	1.53057481751825	0.111019096615915	0.320447102927006
GO:0055106	ubiquitin-protein transferase regulator activity	12/4384	36/18639	0.333333333333333	1.41719890510949	0.118517207988446	0.341329559006725
GO:0004629	phospholipase C activity	10/4384	29/18639	0.344827586206897	1.46606783287189	0.122193554691307	0.351137132771472
GO:0005048	signal sequence binding	16/4384	51/18639	0.313725490196078	1.33383426363246	0.124794400155689	0.357817572127817
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	13/4384	40/18639	0.325	1.38176893248175	0.125841900619084	0.360024510380426
GO:0004126	cytidine deaminase activity	5/4384	12/18639	0.416666666666667	1.77149863138686	0.128564679861312	0.364594803282845
GO:0034452	dynactin binding	5/4384	12/18639	0.416666666666667	1.77149863138686	0.128564679861312	0.364594803282845
GO:0035014	phosphatidylinositol 3-kinase regulator activity	5/4384	12/18639	0.416666666666667	1.77149863138686	0.128564679861312	0.364594803282845
GO:0070679	inositol 1,4,5 trisphosphate binding	5/4384	12/18639	0.416666666666667	1.77149863138686	0.128564679861312	0.364594803282845
GO:0019956	chemokine binding	11/4384	33/18639	0.333333333333333	1.41719890510949	0.131616110499402	0.372433360714466
GO:0004435	phosphatidylinositol phospholipase C activity	9/4384	26/18639	0.346153846153846	1.47170655530601	0.135977050169813	0.379797967715686
GO:0004529	DNA exonuclease activity	9/4384	26/18639	0.346153846153846	1.47170655530601	0.135977050169813	0.379797967715686
GO:0008143	poly(A) binding	9/4384	26/18639	0.346153846153846	1.47170655530601	0.135977050169813	0.379797967715686
GO:0008157	protein phosphatase 1 binding	9/4384	26/18639	0.346153846153846	1.47170655530601	0.135977050169813	0.379797967715686
GO:0034237	protein kinase A regulatory subunit binding	9/4384	26/18639	0.346153846153846	1.47170655530601	0.135977050169813	0.379797967715686
GO:0052742	phosphatidylinositol kinase activity	9/4384	26/18639	0.346153846153846	1.47170655530601	0.135977050169813	0.379797967715686
GO:1990380	K48-linked deubiquitinase activity	7/4384	19/18639	0.368421052631579	1.56637773722628	0.136865588124856	0.38145763916089
GO:0042169	SH2 domain binding	13/4384	41/18639	0.317073170731707	1.34806725120171	0.146500545568644	0.40659055412841
GO:0051721	protein phosphatase 2A binding	10/4384	30/18639	0.333333333333333	1.41719890510949	0.146510639489173	0.40659055412841
GO:0043274	phospholipase binding	8/4384	23/18639	0.347826086956522	1.4788162488099	0.151750804314931	0.414251736934858
GO:0140103	catalytic activity, acting on a glycoprotein	8/4384	23/18639	0.347826086956522	1.4788162488099	0.151750804314931	0.414251736934858
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	6/4384	16/18639	0.375	1.59434876824818	0.152467653177413	0.414251736934858
GO:0008296	3'-5'-DNA exonuclease activity	6/4384	16/18639	0.375	1.59434876824818	0.152467653177413	0.414251736934858
GO:0022858	alanine transmembrane transporter activity	6/4384	16/18639	0.375	1.59434876824818	0.152467653177413	0.414251736934858
GO:0030275	LRR domain binding	6/4384	16/18639	0.375	1.59434876824818	0.152467653177413	0.414251736934858
GO:0097027	ubiquitin-protein transferase activator activity	6/4384	16/18639	0.375	1.59434876824818	0.152467653177413	0.414251736934858
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	6/4384	16/18639	0.375	1.59434876824818	0.152467653177413	0.414251736934858
GO:0140327	flippase activity	6/4384	16/18639	0.375	1.59434876824818	0.152467653177413	0.414251736934858
GO:0140328	floppase activity	6/4384	16/18639	0.375	1.59434876824818	0.152467653177413	0.414251736934858
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	36/4384	130/18639	0.276923076923077	1.17736524424481	0.153525831511339	0.416254137319447
GO:0004519	endonuclease activity	35/4384	127/18639	0.275590551181102	1.17169988217714	0.165225288229199	0.447039610741214
GO:0016504	peptidase activator activity	17/4384	57/18639	0.298245614035088	1.2680200729927	0.165978798627439	0.448142756294086
GO:0051117	ATPase binding	24/4384	84/18639	0.285714285714286	1.21474191866528	0.166727639011998	0.449228732140435
GO:0031492	nucleosomal DNA binding	13/4384	42/18639	0.30952380952381	1.31597041188738	0.168843200525226	0.450342708511933
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	18/4384	61/18639	0.295081967213115	1.25456952255594	0.169424953796719	0.450342708511933
GO:0016408	C-acyltransferase activity	7/4384	20/18639	0.35	1.48805885036496	0.16995336056533	0.450342708511933
GO:0016505	peptidase activator activity involved in apoptotic process	7/4384	20/18639	0.35	1.48805885036496	0.16995336056533	0.450342708511933
GO:0030742	GTP-dependent protein binding	7/4384	20/18639	0.35	1.48805885036496	0.16995336056533	0.450342708511933
GO:0042288	MHC class I protein binding	7/4384	20/18639	0.35	1.48805885036496	0.16995336056533	0.450342708511933
GO:0005035	death receptor activity	5/4384	13/18639	0.384615384615385	1.63522950589556	0.170268462323185	0.450342708511933
GO:0019104	DNA N-glycosylase activity	5/4384	13/18639	0.384615384615385	1.63522950589556	0.170268462323185	0.450342708511933
GO:0019855	calcium channel inhibitor activity	5/4384	13/18639	0.384615384615385	1.63522950589556	0.170268462323185	0.450342708511933
GO:0008327	methyl-CpG binding	10/4384	31/18639	0.32258064516129	1.37148281139628	0.173084087213977	0.456857387025079
GO:0030291	protein serine/threonine kinase inhibitor activity	14/4384	46/18639	0.304347826086957	1.29396421770866	0.174157155714455	0.458755434564906
GO:0019957	C-C chemokine binding	8/4384	24/18639	0.333333333333333	1.41719890510949	0.183209635068278	0.479676135451491
GO:0070840	dynein complex binding	8/4384	24/18639	0.333333333333333	1.41719890510949	0.183209635068278	0.479676135451491
GO:0140612	DNA damage sensor activity	8/4384	24/18639	0.333333333333333	1.41719890510949	0.183209635068278	0.479676135451491
GO:0005031	tumor necrosis factor receptor activity	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0005131	growth hormone receptor binding	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0005522	profilin binding	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0005528	FK506 binding	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0008140	cAMP response element binding protein binding	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0031957	very long-chain fatty acid-CoA ligase activity	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0032356	oxidized DNA binding	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0033204	ribonuclease P RNA binding	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0140940	histone H2A methyltransferase activity	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:1990259	histone H2AQ104 methyltransferase activity	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:1990757	ubiquitin ligase activator activity	4/4384	10/18639	0.4	1.70063868613139	0.190589104378938	0.480199591492624
GO:1990782	protein tyrosine kinase binding	32/4384	117/18639	0.273504273504274	1.16282987085907	0.190708607102646	0.480199591492624
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	6/4384	17/18639	0.352941176470588	1.50056354658652	0.191190578094286	0.480199591492624
GO:0031489	myosin V binding	6/4384	17/18639	0.352941176470588	1.50056354658652	0.191190578094286	0.480199591492624
GO:0008375	acetylglucosaminyltransferase activity	13/4384	43/18639	0.302325581395349	1.28536644882023	0.192770998190295	0.483232521575672
GO:0008378	galactosyltransferase activity	10/4384	32/18639	0.3125	1.32862397354015	0.201726802229905	0.503733980134791
GO:0022884	macromolecule transmembrane transporter activity	10/4384	32/18639	0.3125	1.32862397354015	0.201726802229905	0.503733980134791
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	12/4384	40/18639	0.3	1.27547901459854	0.213726195545175	0.532671441204897
GO:0005545	1-phosphatidylinositol binding	5/4384	14/18639	0.357142857142857	1.5184273983316	0.216345029448862	0.535082362911689
GO:0046030	inositol trisphosphate phosphatase activity	5/4384	14/18639	0.357142857142857	1.5184273983316	0.216345029448862	0.535082362911689
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	5/4384	14/18639	0.357142857142857	1.5184273983316	0.216345029448862	0.535082362911689
GO:1990825	sequence-specific mRNA binding	5/4384	14/18639	0.357142857142857	1.5184273983316	0.216345029448862	0.535082362911689
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	8/4384	25/18639	0.32	1.36051094890511	0.217181653163508	0.535109168250772
GO:0019211	phosphatase activator activity	8/4384	25/18639	0.32	1.36051094890511	0.217181653163508	0.535109168250772
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	9/4384	29/18639	0.310344827586207	1.3194610495847	0.225631485682913	0.553822737585332
GO:0097472	cyclin-dependent protein kinase activity	9/4384	29/18639	0.310344827586207	1.3194610495847	0.225631485682913	0.553822737585332
GO:0016853	isomerase activity	47/4384	180/18639	0.261111111111111	1.11013914233577	0.229006036165936	0.561043143423541
GO:0000400	four-way junction DNA binding	6/4384	18/18639	0.333333333333333	1.41719890510949	0.233151157081374	0.564792335658806
GO:0000900	mRNA regulatory element binding translation repressor activity	6/4384	18/18639	0.333333333333333	1.41719890510949	0.233151157081374	0.564792335658806
GO:0008308	voltage-gated monoatomic anion channel activity	6/4384	18/18639	0.333333333333333	1.41719890510949	0.233151157081374	0.564792335658806
GO:0008525	phosphatidylcholine transporter activity	6/4384	18/18639	0.333333333333333	1.41719890510949	0.233151157081374	0.564792335658806
GO:0031690	adrenergic receptor binding	6/4384	18/18639	0.333333333333333	1.41719890510949	0.233151157081374	0.564792335658806
GO:0050811	GABA receptor binding	6/4384	18/18639	0.333333333333333	1.41719890510949	0.233151157081374	0.564792335658806
GO:0061133	endopeptidase activator activity	7/4384	22/18639	0.318181818181818	1.35278077305906	0.244828269452547	0.59013806696477
GO:0008526	phosphatidylinositol transfer activity	4/4384	11/18639	0.363636363636364	1.54603516921035	0.246801568128785	0.59013806696477
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	4/4384	11/18639	0.363636363636364	1.54603516921035	0.246801568128785	0.59013806696477
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/4384	11/18639	0.363636363636364	1.54603516921035	0.246801568128785	0.59013806696477
GO:0019206	nucleoside kinase activity	4/4384	11/18639	0.363636363636364	1.54603516921035	0.246801568128785	0.59013806696477
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	4/4384	11/18639	0.363636363636364	1.54603516921035	0.246801568128785	0.59013806696477
GO:0047676	arachidonate-CoA ligase activity	4/4384	11/18639	0.363636363636364	1.54603516921035	0.246801568128785	0.59013806696477
GO:0016860	intramolecular oxidoreductase activity	15/4384	53/18639	0.283018867924528	1.20328208924391	0.249675094765074	0.594814196352088
GO:0051018	protein kinase A binding	15/4384	53/18639	0.283018867924528	1.20328208924391	0.249675094765074	0.594814196352088
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	8/4384	26/18639	0.307692307692308	1.30818360471645	0.253272587827372	0.601174494183651
GO:0097602	cullin family protein binding	8/4384	26/18639	0.307692307692308	1.30818360471645	0.253272587827372	0.601174494183651
GO:0120013	lipid transfer activity	18/4384	65/18639	0.276923076923077	1.17736524424481	0.253808576623729	0.601345366187116
GO:0030971	receptor tyrosine kinase binding	22/4384	81/18639	0.271604938271605	1.15475466342255	0.255894308907539	0.605180701357976
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	5/4384	15/18639	0.333333333333333	1.41719890510949	0.265685672959271	0.621531826994972
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	5/4384	15/18639	0.333333333333333	1.41719890510949	0.265685672959271	0.621531826994972
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	5/4384	15/18639	0.333333333333333	1.41719890510949	0.265685672959271	0.621531826994972
GO:0048531	beta-1,3-galactosyltransferase activity	5/4384	15/18639	0.333333333333333	1.41719890510949	0.265685672959271	0.621531826994972
GO:0055105	ubiquitin-protein transferase inhibitor activity	5/4384	15/18639	0.333333333333333	1.41719890510949	0.265685672959271	0.621531826994972
GO:0120283	protein serine/threonine kinase binding	5/4384	15/18639	0.333333333333333	1.41719890510949	0.265685672959271	0.621531826994972
GO:0043531	ADP binding	11/4384	38/18639	0.289473684210526	1.2307253649635	0.267872685282458	0.625518919146063
GO:0016859	cis-trans isomerase activity	12/4384	42/18639	0.285714285714286	1.21474191866528	0.270623908022316	0.630806807188709
GO:0030276	clathrin binding	13/4384	46/18639	0.282608695652174	1.20153820215804	0.272717434374316	0.634545412835034
GO:0097110	scaffold protein binding	19/4384	70/18639	0.271428571428571	1.15400482273201	0.277270989834768	0.641278935789507
GO:0008301	DNA binding, bending	6/4384	19/18639	0.315789473684211	1.34260948905109	0.277590650445921	0.641278935789507
GO:0008574	plus-end-directed microtubule motor activity	6/4384	19/18639	0.315789473684211	1.34260948905109	0.277590650445921	0.641278935789507
GO:0046624	sphingolipid transporter activity	6/4384	19/18639	0.315789473684211	1.34260948905109	0.277590650445921	0.641278935789507
GO:0008171	O-methyltransferase activity	7/4384	23/18639	0.304347826086957	1.29396421770866	0.285549660450255	0.657322131338419
GO:0016493	C-C chemokine receptor activity	7/4384	23/18639	0.304347826086957	1.29396421770866	0.285549660450255	0.657322131338419
GO:0008320	protein transmembrane transporter activity	8/4384	27/18639	0.296296296296296	1.25973236009732	0.291048937003373	0.668793302050303
GO:0016411	acylglycerol O-acyltransferase activity	9/4384	31/18639	0.290322580645161	1.23433453025665	0.294908919446295	0.67407753016296
GO:0016878	acid-thiol ligase activity	9/4384	31/18639	0.290322580645161	1.23433453025665	0.294908919446295	0.67407753016296
GO:0070273	phosphatidylinositol-4-phosphate binding	9/4384	31/18639	0.290322580645161	1.23433453025665	0.294908919446295	0.67407753016296
GO:0000217	DNA secondary structure binding	11/4384	39/18639	0.282051282051282	1.19916830432341	0.299502312438394	0.682170469103969
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	11/4384	39/18639	0.282051282051282	1.19916830432341	0.299502312438394	0.682170469103969
GO:0043495	protein-membrane adaptor activity	13/4384	47/18639	0.276595744680851	1.17597355955894	0.301542981750317	0.682396447318808
GO:0003995	acyl-CoA dehydrogenase activity	4/4384	12/18639	0.333333333333333	1.41719890510949	0.305920012262521	0.682396447318808
GO:0004000	adenosine deaminase activity	4/4384	12/18639	0.333333333333333	1.41719890510949	0.305920012262521	0.682396447318808
GO:0004526	ribonuclease P activity	4/4384	12/18639	0.333333333333333	1.41719890510949	0.305920012262521	0.682396447318808
GO:0005078	MAP-kinase scaffold activity	4/4384	12/18639	0.333333333333333	1.41719890510949	0.305920012262521	0.682396447318808
GO:0005527	macrolide binding	4/4384	12/18639	0.333333333333333	1.41719890510949	0.305920012262521	0.682396447318808
GO:0016423	tRNA (guanine) methyltransferase activity	4/4384	12/18639	0.333333333333333	1.41719890510949	0.305920012262521	0.682396447318808
GO:0035497	cAMP response element binding	4/4384	12/18639	0.333333333333333	1.41719890510949	0.305920012262521	0.682396447318808
GO:0036009	protein-glutamine N-methyltransferase activity	4/4384	12/18639	0.333333333333333	1.41719890510949	0.305920012262521	0.682396447318808
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	4/4384	12/18639	0.333333333333333	1.41719890510949	0.305920012262521	0.682396447318808
GO:0097677	STAT family protein binding	4/4384	12/18639	0.333333333333333	1.41719890510949	0.305920012262521	0.682396447318808
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	4/4384	12/18639	0.333333333333333	1.41719890510949	0.305920012262521	0.682396447318808
GO:0004707	MAP kinase activity	5/4384	16/18639	0.3125	1.32862397354015	0.317148409223752	0.705016017759832
GO:0015923	mannosidase activity	5/4384	16/18639	0.3125	1.32862397354015	0.317148409223752	0.705016017759832
GO:0015095	magnesium ion transmembrane transporter activity	6/4384	20/18639	0.3	1.27547901459854	0.323720917537603	0.717166340390998
GO:0140664	ATP-dependent DNA damage sensor activity	6/4384	20/18639	0.3	1.27547901459854	0.323720917537603	0.717166340390998
GO:0001217	DNA-binding transcription repressor activity	69/4384	278/18639	0.248201438848921	1.05525242214987	0.325205546551262	0.719225918652621
GO:0070300	phosphatidic acid binding	7/4384	24/18639	0.291666666666667	1.2400490419708	0.327689670901657	0.722015692728206
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	16/4384	60/18639	0.266666666666667	1.13375912408759	0.328294920554767	0.722015692728206
GO:0019212	phosphatase inhibitor activity	15/4384	56/18639	0.267857142857143	1.1388205487487	0.329387579086309	0.722015692728206
GO:0016248	channel inhibitor activity	12/4384	44/18639	0.272727272727273	1.15952637690776	0.331735787163386	0.722015692728206
GO:0019205	nucleobase-containing compound kinase activity	12/4384	44/18639	0.272727272727273	1.15952637690776	0.331735787163386	0.722015692728206
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	10/4384	36/18639	0.277777777777778	1.18099908759124	0.331962704981065	0.722015692728206
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	10/4384	36/18639	0.277777777777778	1.18099908759124	0.331962704981065	0.722015692728206
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	10/4384	36/18639	0.277777777777778	1.18099908759124	0.331962704981065	0.722015692728206
GO:0004177	aminopeptidase activity	11/4384	40/18639	0.275	1.16918909671533	0.332038080915132	0.722015692728206
GO:0015036	disulfide oxidoreductase activity	11/4384	40/18639	0.275	1.16918909671533	0.332038080915132	0.722015692728206
GO:0016874	ligase activity	42/4384	167/18639	0.251497005988024	1.06926384457363	0.337217254740362	0.732049517828323
GO:0051213	dioxygenase activity	24/4384	93/18639	0.258064516129032	1.09718624911702	0.338613995174554	0.733852404257896
GO:0015026	coreceptor activity	16/4384	61/18639	0.262295081967213	1.11517290893861	0.355156355016165	0.767137726834916
GO:0019905	syntaxin binding	16/4384	61/18639	0.262295081967213	1.11517290893861	0.355156355016165	0.767137726834916
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	66/4384	268/18639	0.246268656716418	1.04703501198388	0.356316670018338	0.768363401570327
GO:0035254	glutamate receptor binding	13/4384	49/18639	0.26530612244898	1.12797463876061	0.36134697149739	0.777916403755179
GO:0141110	transporter inhibitor activity	12/4384	45/18639	0.266666666666667	1.13375912408759	0.363325730648567	0.779322871358433
GO:0005338	nucleotide-sugar transmembrane transporter activity	4/4384	13/18639	0.307692307692308	1.30818360471645	0.366209590013338	0.779322871358433
GO:0009982	pseudouridine synthase activity	4/4384	13/18639	0.307692307692308	1.30818360471645	0.366209590013338	0.779322871358433
GO:0035673	oligopeptide transmembrane transporter activity	4/4384	13/18639	0.307692307692308	1.30818360471645	0.366209590013338	0.779322871358433
GO:0043560	insulin receptor substrate binding	4/4384	13/18639	0.307692307692308	1.30818360471645	0.366209590013338	0.779322871358433
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	4/4384	13/18639	0.307692307692308	1.30818360471645	0.366209590013338	0.779322871358433
GO:0140333	glycerophospholipid flippase activity	4/4384	13/18639	0.307692307692308	1.30818360471645	0.366209590013338	0.779322871358433
GO:0023023	MHC protein complex binding	10/4384	37/18639	0.27027027027027	1.14908019333202	0.3669846353966	0.779691946678679
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	5/4384	17/18639	0.294117647058824	1.25046962215543	0.369630838861029	0.780051913579033
GO:0008429	phosphatidylethanolamine binding	5/4384	17/18639	0.294117647058824	1.25046962215543	0.369630838861029	0.780051913579033
GO:0035250	UDP-galactosyltransferase activity	8/4384	29/18639	0.275862068965517	1.17285426629751	0.369837441643886	0.780051913579033
GO:0004709	MAP kinase kinase kinase activity	7/4384	25/18639	0.28	1.19044708029197	0.370665011133159	0.780051913579033
GO:0005123	death receptor binding	6/4384	21/18639	0.285714285714286	1.21474191866528	0.370765415713491	0.780051913579033
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	6/4384	21/18639	0.285714285714286	1.21474191866528	0.370765415713491	0.780051913579033
GO:0002020	protease binding	34/4384	136/18639	0.25	1.06289917883212	0.373482712463889	0.784495292306645
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	12/4384	46/18639	0.260869565217391	1.10911218660743	0.395305129333597	0.828989397437445
GO:0015035	protein-disulfide reductase activity	9/4384	34/18639	0.264705882352941	1.12542265993989	0.406100405347122	0.848880847306242
GO:0016831	carboxy-lyase activity	9/4384	34/18639	0.264705882352941	1.12542265993989	0.406100405347122	0.848880847306242
GO:0001637	G protein-coupled chemoattractant receptor activity	7/4384	26/18639	0.269230769230769	1.14466065412689	0.41391485129845	0.856922759237685
GO:0004950	chemokine receptor activity	7/4384	26/18639	0.269230769230769	1.14466065412689	0.41391485129845	0.856922759237685
GO:0005112	Notch binding	7/4384	26/18639	0.269230769230769	1.14466065412689	0.41391485129845	0.856922759237685
GO:0043548	phosphatidylinositol 3-kinase binding	7/4384	26/18639	0.269230769230769	1.14466065412689	0.41391485129845	0.856922759237685
GO:0070006	metalloaminopeptidase activity	7/4384	26/18639	0.269230769230769	1.14466065412689	0.41391485129845	0.856922759237685
GO:0120014	phospholipid transfer activity	7/4384	26/18639	0.269230769230769	1.14466065412689	0.41391485129845	0.856922759237685
GO:0004706	JUN kinase kinase kinase activity	5/4384	18/18639	0.277777777777778	1.18099908759124	0.422123024160897	0.859234354476156
GO:1990381	ubiquitin-specific protease binding	5/4384	18/18639	0.277777777777778	1.18099908759124	0.422123024160897	0.859234354476156
GO:0017022	myosin binding	19/4384	76/18639	0.25	1.06289917883212	0.423802606283261	0.859234354476156
GO:0004705	JUN kinase activity	4/4384	14/18639	0.285714285714286	1.21474191866528	0.426155414239128	0.859234354476156
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	4/4384	14/18639	0.285714285714286	1.21474191866528	0.426155414239128	0.859234354476156
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	4/4384	14/18639	0.285714285714286	1.21474191866528	0.426155414239128	0.859234354476156
GO:0044548	S100 protein binding	4/4384	14/18639	0.285714285714286	1.21474191866528	0.426155414239128	0.859234354476156
GO:0001094	TFIID-class transcription factor complex binding	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0004445	inositol-polyphosphate 5-phosphatase activity	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0004955	prostaglandin receptor activity	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0005381	iron ion transmembrane transporter activity	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0008239	dipeptidyl-peptidase activity	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0016783	sulfurtransferase activity	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0016868	intramolecular phosphotransferase activity	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0043295	glutathione binding	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0047429	nucleoside triphosphate diphosphatase activity	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0097177	mitochondrial ribosome binding	3/4384	10/18639	0.3	1.27547901459854	0.429617177238078	0.859234354476156
GO:0008200	ion channel inhibitor activity	11/4384	43/18639	0.255813953488372	1.08761776438635	0.432481556504847	0.863630350123701
GO:0016776	phosphotransferase activity, phosphate group as acceptor	10/4384	39/18639	0.256410256410256	1.09015300393038	0.43785743216115	0.873020357047462
GO:0001618	virus receptor activity	20/4384	81/18639	0.246913580246914	1.04977696674777	0.444188982233117	0.884284056795883
GO:0004713	protein tyrosine kinase activity	34/4384	140/18639	0.242857142857143	1.03253063086548	0.447733074379769	0.889972491405185
GO:0004521	RNA endonuclease activity	18/4384	73/18639	0.246575342465753	1.04833891610839	0.454103847689671	0.901253578263115
GO:0035255	ionotropic glutamate receptor binding	7/4384	27/18639	0.259259259259259	1.10226581508516	0.456917921301727	0.905452027533697
GO:0140272	exogenous protein binding	20/4384	82/18639	0.24390243902439	1.0369748086167	0.468730158910375	0.927441657935643
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	5/4384	19/18639	0.263157894736842	1.11884124087591	0.473741729059103	0.934504232664531
GO:0050145	nucleoside monophosphate kinase activity	5/4384	19/18639	0.263157894736842	1.11884124087591	0.473741729059103	0.934504232664531
GO:0016409	palmitoyltransferase activity	9/4384	36/18639	0.25	1.06289917883212	0.480879955614255	0.945666309445207
GO:0004864	protein phosphatase inhibitor activity	13/4384	53/18639	0.245283018867925	1.04284447734472	0.4841157609992	0.945666309445207
GO:0004467	long-chain fatty acid-CoA ligase activity	4/4384	15/18639	0.266666666666667	1.13375912408759	0.484508047431804	0.945666309445207
GO:0004559	alpha-mannosidase activity	4/4384	15/18639	0.266666666666667	1.13375912408759	0.484508047431804	0.945666309445207
GO:0004953	icosanoid receptor activity	4/4384	15/18639	0.266666666666667	1.13375912408759	0.484508047431804	0.945666309445207
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/4384	15/18639	0.266666666666667	1.13375912408759	0.484508047431804	0.945666309445207
GO:0050780	dopamine receptor binding	4/4384	15/18639	0.266666666666667	1.13375912408759	0.484508047431804	0.945666309445207
GO:0008081	phosphoric diester hydrolase activity	21/4384	87/18639	0.241379310344828	1.02624748301032	0.48735578556744	0.947431337319554
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	3/4384	11/18639	0.272727272727273	1.15952637690776	0.498173030654063	0.947431337319554
GO:0003953	NAD+ nucleosidase activity	3/4384	11/18639	0.272727272727273	1.15952637690776	0.498173030654063	0.947431337319554
GO:0004954	prostanoid receptor activity	3/4384	11/18639	0.272727272727273	1.15952637690776	0.498173030654063	0.947431337319554
GO:0008432	JUN kinase binding	3/4384	11/18639	0.272727272727273	1.15952637690776	0.498173030654063	0.947431337319554
GO:0010854	adenylate cyclase regulator activity	3/4384	11/18639	0.272727272727273	1.15952637690776	0.498173030654063	0.947431337319554
GO:0015217	ADP transmembrane transporter activity	3/4384	11/18639	0.272727272727273	1.15952637690776	0.498173030654063	0.947431337319554
GO:0019215	intermediate filament binding	3/4384	11/18639	0.272727272727273	1.15952637690776	0.498173030654063	0.947431337319554
GO:0032050	clathrin heavy chain binding	3/4384	11/18639	0.272727272727273	1.15952637690776	0.498173030654063	0.947431337319554
GO:0034713	type I transforming growth factor beta receptor binding	3/4384	11/18639	0.272727272727273	1.15952637690776	0.498173030654063	0.947431337319554
GO:0043522	leucine zipper domain binding	3/4384	11/18639	0.272727272727273	1.15952637690776	0.498173030654063	0.947431337319554
GO:0180030	inositol phosphate kinase activity	3/4384	11/18639	0.272727272727273	1.15952637690776	0.498173030654063	0.947431337319554
GO:1900750	oligopeptide binding	3/4384	11/18639	0.272727272727273	1.15952637690776	0.498173030654063	0.947431337319554
GO:1990948	ubiquitin ligase inhibitor activity	3/4384	11/18639	0.272727272727273	1.15952637690776	0.498173030654063	0.947431337319554
GO:0016866	intramolecular transferase activity	7/4384	28/18639	0.25	1.06289917883212	0.499205065643855	0.947431337319554
GO:0046875	ephrin receptor binding	7/4384	28/18639	0.25	1.06289917883212	0.499205065643855	0.947431337319554
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	7/4384	28/18639	0.25	1.06289917883212	0.499205065643855	0.947431337319554
GO:0042605	peptide antigen binding	11/4384	45/18639	0.244444444444444	1.03927919708029	0.499302163108993	0.947431337319554
GO:0046915	transition metal ion transmembrane transporter activity	11/4384	45/18639	0.244444444444444	1.03927919708029	0.499302163108993	0.947431337319554
GO:0050699	WW domain binding	6/4384	24/18639	0.25	1.06289917883212	0.510418304617833	0.967108366644316
GO:0015485	cholesterol binding	13/4384	54/18639	0.240740740740741	1.02353254257908	0.5143810744356	0.971775324298159
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	13/4384	54/18639	0.240740740740741	1.02353254257908	0.5143810744356	0.971775324298159
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	16/4384	67/18639	0.238805970149254	1.0153066782874	0.519599139807641	0.979188679736979
GO:0005319	lipid transporter activity	42/4384	178/18639	0.235955056179775	1.00318574181908	0.519816212699878	0.979188679736979
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	4/4384	16/18639	0.25	1.06289917883212	0.540294593501154	1
GO:0005159	insulin-like growth factor receptor binding	4/4384	16/18639	0.25	1.06289917883212	0.540294593501154	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	4/4384	16/18639	0.25	1.06289917883212	0.540294593501154	1
GO:0070411	I-SMAD binding	4/4384	16/18639	0.25	1.06289917883212	0.540294593501154	1
GO:0016417	S-acyltransferase activity	7/4384	29/18639	0.241379310344828	1.02624748301032	0.540367491462027	1
GO:0035401	histone H3Y41 kinase activity	27/4384	115/18639	0.234782608695652	0.998200967946684	0.540550543392994	1
GO:0140801	histone H2AXY142 kinase activity	27/4384	115/18639	0.234782608695652	0.998200967946684	0.540550543392994	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	6/4384	25/18639	0.24	1.02038321167883	0.554550923612993	1
GO:0019707	protein-cysteine S-acyltransferase activity	6/4384	25/18639	0.24	1.02038321167883	0.554550923612993	1
GO:0003720	telomerase activity	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0004300	enoyl-CoA hydratase activity	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0005165	neurotrophin receptor binding	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0008179	adenylate cyclase binding	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0008603	cAMP-dependent protein kinase regulator activity	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0010853	cyclase activator activity	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0016801	hydrolase activity, acting on ether bonds	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0016803	ether hydrolase activity	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0017166	vinculin binding	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0031543	peptidyl-proline dioxygenase activity	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0035251	UDP-glucosyltransferase activity	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0042301	phosphate ion binding	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0045295	gamma-catenin binding	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:1990459	transferrin receptor binding	3/4384	12/18639	0.25	1.06289917883212	0.56225737011791	1
GO:0140359	ABC-type transporter activity	11/4384	47/18639	0.234042553191489	0.995054550396024	0.563928132144243	1
GO:0050660	flavin adenine dinucleotide binding	20/4384	86/18639	0.232558139534884	0.988743422169411	0.564933392904822	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	8/4384	34/18639	0.235294117647059	1.00037569772435	0.565748981835326	1
GO:0010314	phosphatidylinositol-5-phosphate binding	5/4384	21/18639	0.238095238095238	1.01228493222106	0.571555932020262	1
GO:0140312	cargo adaptor activity	5/4384	21/18639	0.238095238095238	1.01228493222106	0.571555932020262	1
GO:1904047	S-adenosyl-L-methionine binding	5/4384	21/18639	0.238095238095238	1.01228493222106	0.571555932020262	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	10/4384	43/18639	0.232558139534884	0.988743422169411	0.575254634288249	1
GO:0001965	G-protein alpha-subunit binding	7/4384	30/18639	0.233333333333333	0.992039233576642	0.580061156376708	1
GO:0004549	tRNA-specific ribonuclease activity	4/4384	17/18639	0.235294117647059	1.00037569772435	0.592806518005808	1
GO:0015278	intracellularly gated calcium channel activity	4/4384	17/18639	0.235294117647059	1.00037569772435	0.592806518005808	1
GO:0017110	nucleoside diphosphate phosphatase activity	4/4384	17/18639	0.235294117647059	1.00037569772435	0.592806518005808	1
GO:0032977	membrane insertase activity	4/4384	17/18639	0.235294117647059	1.00037569772435	0.592806518005808	1
GO:0036041	long-chain fatty acid binding	4/4384	17/18639	0.235294117647059	1.00037569772435	0.592806518005808	1
GO:0046965	nuclear retinoid X receptor binding	4/4384	17/18639	0.235294117647059	1.00037569772435	0.592806518005808	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	11/4384	48/18639	0.229166666666667	0.974324247262774	0.594958728969012	1
GO:0032266	phosphatidylinositol-3-phosphate binding	11/4384	48/18639	0.229166666666667	0.974324247262774	0.594958728969012	1
GO:0030507	spectrin binding	6/4384	26/18639	0.230769230769231	0.981137703537339	0.596741745307356	1
GO:0043178	alcohol binding	21/4384	92/18639	0.228260869565217	0.970473163281498	0.602689893361543	1
GO:0003954	NADH dehydrogenase activity	10/4384	44/18639	0.227272727272727	0.96627198075647	0.607369679779303	1
GO:0005246	calcium channel regulator activity	12/4384	53/18639	0.226415094339623	0.962625671395125	0.612777955767937	1
GO:0003964	RNA-directed DNA polymerase activity	3/4384	13/18639	0.230769230769231	0.981137703537339	0.621071704149282	1
GO:0008253	5'-nucleotidase activity	3/4384	13/18639	0.230769230769231	0.981137703537339	0.621071704149282	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/4384	13/18639	0.230769230769231	0.981137703537339	0.621071704149282	1
GO:0031432	titin binding	3/4384	13/18639	0.230769230769231	0.981137703537339	0.621071704149282	1
GO:0045159	myosin II binding	3/4384	13/18639	0.230769230769231	0.981137703537339	0.621071704149282	1
GO:0089720	caspase binding	3/4384	13/18639	0.230769230769231	0.981137703537339	0.621071704149282	1
GO:0071949	FAD binding	9/4384	40/18639	0.225	0.956609260948905	0.621115092060933	1
GO:0016757	glycosyltransferase activity	61/4384	267/18639	0.228464419475655	0.971338575412122	0.626666937419412	1
GO:1902936	phosphatidylinositol bisphosphate binding	25/4384	111/18639	0.225225225225225	0.957566827776682	0.634355511809201	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	6/4384	27/18639	0.222222222222222	0.944799270072993	0.636691409308965	1
GO:0016405	CoA-ligase activity	6/4384	27/18639	0.222222222222222	0.944799270072993	0.636691409308965	1
GO:0035615	clathrin adaptor activity	4/4384	18/18639	0.222222222222222	0.944799270072993	0.641573230532925	1
GO:0008137	NADH dehydrogenase (ubiquinone) activity	9/4384	41/18639	0.219512195121951	0.933277327755029	0.652945414311728	1
GO:0120015	sterol transfer activity	7/4384	32/18639	0.21875	0.930036781478102	0.653993694382065	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	15/4384	68/18639	0.220588235294118	0.937852216616574	0.657843970432573	1
GO:0032934	sterol binding	15/4384	68/18639	0.220588235294118	0.937852216616574	0.657843970432573	1
GO:0031681	G-protein beta-subunit binding	5/4384	23/18639	0.217391304347826	0.924260155506189	0.658940088028269	1
GO:0005161	platelet-derived growth factor receptor binding	3/4384	14/18639	0.214285714285714	0.911056438998957	0.674230692306596	1
GO:0005347	ATP transmembrane transporter activity	3/4384	14/18639	0.214285714285714	0.911056438998957	0.674230692306596	1
GO:0016530	metallochaperone activity	3/4384	14/18639	0.214285714285714	0.911056438998957	0.674230692306596	1
GO:0019992	diacylglycerol binding	3/4384	14/18639	0.214285714285714	0.911056438998957	0.674230692306596	1
GO:0032036	myosin heavy chain binding	3/4384	14/18639	0.214285714285714	0.911056438998957	0.674230692306596	1
GO:0005543	phospholipid binding	113/4384	497/18639	0.227364185110664	0.966660822599832	0.678793521792986	1
GO:0004896	cytokine receptor activity	21/4384	96/18639	0.21875	0.930036781478102	0.686310047600545	1
GO:0003756	protein disulfide isomerase activity	4/4384	19/18639	0.210526315789474	0.89507299270073	0.686328297592611	1
GO:0015245	fatty acid transmembrane transporter activity	4/4384	19/18639	0.210526315789474	0.89507299270073	0.686328297592611	1
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	4/4384	19/18639	0.210526315789474	0.89507299270073	0.686328297592611	1
GO:0030296	protein tyrosine kinase activator activity	7/4384	33/18639	0.212121212121212	0.901853848706039	0.687865370704987	1
GO:0044325	transmembrane transporter binding	30/4384	136/18639	0.220588235294118	0.937852216616574	0.688401483018601	1
GO:0005516	calmodulin binding	46/4384	207/18639	0.222222222222222	0.944799270072993	0.696640908840186	1
GO:0015295	solute:proton symporter activity	5/4384	24/18639	0.208333333333333	0.885749315693431	0.698024767873121	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/4384	29/18639	0.206896551724138	0.879640699723131	0.709097300521465	1
GO:0000182	rDNA binding	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0004090	carbonyl reductase (NADPH) activity	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0004382	GDP phosphatase activity	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0004935	adrenergic receptor activity	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0015187	glycine transmembrane transporter activity	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0015279	store-operated calcium channel activity	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0015643	toxic substance binding	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0019911	structural constituent of myelin sheath	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0031434	mitogen-activated protein kinase kinase binding	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0035256	G protein-coupled glutamate receptor binding	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0050308	sugar-phosphatase activity	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0070513	death domain binding	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0141109	transporter activator activity	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:1990763	arrestin family protein binding	2/4384	10/18639	0.2	0.850319343065693	0.721065601082528	1
GO:0005523	tropomyosin binding	3/4384	15/18639	0.2	0.850319343065693	0.721661353525294	1
GO:0008252	nucleotidase activity	3/4384	15/18639	0.2	0.850319343065693	0.721661353525294	1
GO:0016846	carbon-sulfur lyase activity	3/4384	15/18639	0.2	0.850319343065693	0.721661353525294	1
GO:0009055	electron transfer activity	25/4384	116/18639	0.21551724137931	0.916292395544928	0.725390405713874	1
GO:0140299	molecular sensor activity	15/4384	71/18639	0.211267605633803	0.898224658167986	0.72598089219849	1
GO:0031418	L-ascorbic acid binding	4/4384	20/18639	0.2	0.850319343065693	0.72697320543253	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	8/4384	39/18639	0.205128205128205	0.872122403144301	0.729344006785344	1
GO:0004857	enzyme inhibitor activity	93/4384	416/18639	0.223557692307692	0.950477150301797	0.731995964809525	1
GO:0008483	transaminase activity	5/4384	25/18639	0.2	0.850319343065693	0.733893228938153	1
GO:0015645	fatty acid ligase activity	5/4384	25/18639	0.2	0.850319343065693	0.733893228938153	1
GO:0015662	P-type ion transporter activity	5/4384	25/18639	0.2	0.850319343065693	0.733893228938153	1
GO:0120020	cholesterol transfer activity	5/4384	25/18639	0.2	0.850319343065693	0.733893228938153	1
GO:0120515	fatty acid-CoA ligase activity	5/4384	25/18639	0.2	0.850319343065693	0.733893228938153	1
GO:0140358	P-type transmembrane transporter activity	5/4384	25/18639	0.2	0.850319343065693	0.733893228938153	1
GO:0015215	nucleotide transmembrane transporter activity	6/4384	30/18639	0.2	0.850319343065693	0.741356336557654	1
GO:0031210	phosphatidylcholine binding	6/4384	30/18639	0.2	0.850319343065693	0.741356336557654	1
GO:0046982	protein heterodimerization activity	82/4384	369/18639	0.222222222222222	0.944799270072993	0.742106590828678	1
GO:0003774	cytoskeletal motor activity	33/4384	153/18639	0.215686274509804	0.917011056247316	0.744680753851949	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	18/4384	86/18639	0.209302325581395	0.88986907995247	0.752734468084863	1
GO:0015385	sodium:proton antiporter activity	3/4384	16/18639	0.1875	0.797174384124088	0.763515221223173	1
GO:0015562	efflux transmembrane transporter activity	3/4384	16/18639	0.1875	0.797174384124088	0.763515221223173	1
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/4384	16/18639	0.1875	0.797174384124088	0.763515221223173	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/4384	16/18639	0.1875	0.797174384124088	0.763515221223173	1
GO:0009975	cyclase activity	4/4384	21/18639	0.19047619047619	0.809827945776851	0.763541975647182	1
GO:0019200	carbohydrate kinase activity	4/4384	21/18639	0.19047619047619	0.809827945776851	0.763541975647182	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	5/4384	26/18639	0.192307692307692	0.817614752947782	0.766548344088343	1
GO:0005160	transforming growth factor beta receptor binding	5/4384	26/18639	0.192307692307692	0.817614752947782	0.766548344088343	1
GO:0050750	low-density lipoprotein particle receptor binding	5/4384	26/18639	0.192307692307692	0.817614752947782	0.766548344088343	1
GO:0051139	metal cation:proton antiporter activity	5/4384	26/18639	0.192307692307692	0.817614752947782	0.766548344088343	1
GO:0002162	dystroglycan binding	2/4384	11/18639	0.181818181818182	0.773017584605176	0.770597283399965	1
GO:0004016	adenylate cyclase activity	2/4384	11/18639	0.181818181818182	0.773017584605176	0.770597283399965	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	2/4384	11/18639	0.181818181818182	0.773017584605176	0.770597283399965	1
GO:0005225	volume-sensitive anion channel activity	2/4384	11/18639	0.181818181818182	0.773017584605176	0.770597283399965	1
GO:0005536	D-glucose binding	2/4384	11/18639	0.181818181818182	0.773017584605176	0.770597283399965	1
GO:0008172	S-methyltransferase activity	2/4384	11/18639	0.181818181818182	0.773017584605176	0.770597283399965	1
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/4384	11/18639	0.181818181818182	0.773017584605176	0.770597283399965	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/4384	11/18639	0.181818181818182	0.773017584605176	0.770597283399965	1
GO:0019203	carbohydrate phosphatase activity	2/4384	11/18639	0.181818181818182	0.773017584605176	0.770597283399965	1
GO:0034056	estrogen response element binding	2/4384	11/18639	0.181818181818182	0.773017584605176	0.770597283399965	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/4384	11/18639	0.181818181818182	0.773017584605176	0.770597283399965	1
GO:0045294	alpha-catenin binding	2/4384	11/18639	0.181818181818182	0.773017584605176	0.770597283399965	1
GO:0050786	RAGE receptor binding	2/4384	11/18639	0.181818181818182	0.773017584605176	0.770597283399965	1
GO:0051015	actin filament binding	45/4384	209/18639	0.215311004784689	0.915415560716656	0.775768942336933	1
GO:0045505	dynein intermediate chain binding	7/4384	36/18639	0.194444444444444	0.826699361313869	0.776059309748499	1
GO:0008374	O-acyltransferase activity	11/4384	55/18639	0.2	0.850319343065693	0.777576297854298	1
GO:0030165	PDZ domain binding	17/4384	83/18639	0.204819277108434	0.870808965790168	0.780780868126934	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	8/4384	41/18639	0.195121951219512	0.82957984689336	0.781481434534257	1
GO:0098531	ligand-modulated transcription factor activity	12/4384	60/18639	0.2	0.850319343065693	0.784147872430395	1
GO:0016830	carbon-carbon lyase activity	10/4384	51/18639	0.196078431372549	0.833646414770288	0.792581925166299	1
GO:0023026	MHC class II protein complex binding	5/4384	27/18639	0.185185185185185	0.787332725060827	0.796061283810928	1
GO:0008093	cytoskeletal anchor activity	4/4384	22/18639	0.181818181818182	0.773017584605176	0.796168672501601	1
GO:0031683	G-protein beta/gamma-subunit complex binding	4/4384	22/18639	0.181818181818182	0.773017584605176	0.796168672501601	1
GO:0015399	primary active transmembrane transporter activity	35/4384	166/18639	0.210843373493976	0.896420994195761	0.796861433886001	1
GO:0043425	bHLH transcription factor binding	6/4384	32/18639	0.1875	0.797174384124088	0.797952187150593	1
GO:0042626	ATPase-coupled transmembrane transporter activity	20/4384	98/18639	0.204081632653061	0.867672799046626	0.800071058698942	1
GO:0004550	nucleoside diphosphate kinase activity	3/4384	17/18639	0.176470588235294	0.750281773293259	0.800095657626894	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/4384	17/18639	0.176470588235294	0.750281773293259	0.800095657626894	1
GO:0016018	cyclosporin A binding	3/4384	17/18639	0.176470588235294	0.750281773293259	0.800095657626894	1
GO:0019198	transmembrane receptor protein phosphatase activity	3/4384	17/18639	0.176470588235294	0.750281773293259	0.800095657626894	1
GO:0048038	quinone binding	3/4384	17/18639	0.176470588235294	0.750281773293259	0.800095657626894	1
GO:0070402	NADPH binding	3/4384	17/18639	0.176470588235294	0.750281773293259	0.800095657626894	1
GO:0019894	kinesin binding	8/4384	42/18639	0.19047619047619	0.809827945776851	0.804609022947999	1
GO:0005247	voltage-gated chloride channel activity	2/4384	12/18639	0.166666666666667	0.708599452554745	0.812265266056376	1
GO:0005436	sodium:phosphate symporter activity	2/4384	12/18639	0.166666666666667	0.708599452554745	0.812265266056376	1
GO:0015166	polyol transmembrane transporter activity	2/4384	12/18639	0.166666666666667	0.708599452554745	0.812265266056376	1
GO:0015368	calcium:monoatomic cation antiporter activity	2/4384	12/18639	0.166666666666667	0.708599452554745	0.812265266056376	1
GO:0016840	carbon-nitrogen lyase activity	2/4384	12/18639	0.166666666666667	0.708599452554745	0.812265266056376	1
GO:0035259	nuclear glucocorticoid receptor binding	2/4384	12/18639	0.166666666666667	0.708599452554745	0.812265266056376	1
GO:0070008	serine-type exopeptidase activity	2/4384	12/18639	0.166666666666667	0.708599452554745	0.812265266056376	1
GO:0097371	MDM2/MDM4 family protein binding	2/4384	12/18639	0.166666666666667	0.708599452554745	0.812265266056376	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	11/4384	57/18639	0.192982456140351	0.820483576642336	0.817165388524338	1
GO:0015179	L-amino acid transmembrane transporter activity	12/4384	62/18639	0.193548387096774	0.822889686837768	0.821512167196882	1
GO:0022853	active monoatomic ion transmembrane transporter activity	24/4384	118/18639	0.203389830508475	0.864731535321044	0.822219382236592	1
GO:0046625	sphingolipid binding	5/4384	28/18639	0.178571428571429	0.759213699165798	0.82255554445374	1
GO:0005158	insulin receptor binding	4/4384	23/18639	0.173913043478261	0.739408124404951	0.825058900811775	1
GO:0016849	phosphorus-oxygen lyase activity	4/4384	23/18639	0.173913043478261	0.739408124404951	0.825058900811775	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/4384	18/18639	0.166666666666667	0.708599452554745	0.831800143045688	1
GO:0015172	acidic amino acid transmembrane transporter activity	3/4384	18/18639	0.166666666666667	0.708599452554745	0.831800143045688	1
GO:0017075	syntaxin-1 binding	3/4384	18/18639	0.166666666666667	0.708599452554745	0.831800143045688	1
GO:1901611	phosphatidylglycerol binding	3/4384	18/18639	0.166666666666667	0.708599452554745	0.831800143045688	1
GO:0008376	acetylgalactosaminyltransferase activity	6/4384	34/18639	0.176470588235294	0.750281773293259	0.844463941762452	1
GO:0051427	hormone receptor binding	6/4384	34/18639	0.176470588235294	0.750281773293259	0.844463941762452	1
GO:0003785	actin monomer binding	5/4384	29/18639	0.172413793103448	0.733033916435943	0.846192678606297	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/4384	13/18639	0.153846153846154	0.654091802358226	0.847027731857666	1
GO:0008417	fucosyltransferase activity	2/4384	13/18639	0.153846153846154	0.654091802358226	0.847027731857666	1
GO:0017154	semaphorin receptor activity	2/4384	13/18639	0.153846153846154	0.654091802358226	0.847027731857666	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/4384	13/18639	0.153846153846154	0.654091802358226	0.847027731857666	1
GO:0061459	L-arginine transmembrane transporter activity	2/4384	13/18639	0.153846153846154	0.654091802358226	0.847027731857666	1
GO:0071837	HMG box domain binding	2/4384	13/18639	0.153846153846154	0.654091802358226	0.847027731857666	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	10/4384	54/18639	0.185185185185185	0.787332725060827	0.848849024740236	1
GO:0005315	phosphate transmembrane transporter activity	4/4384	24/18639	0.166666666666667	0.708599452554745	0.850465727399507	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	4/4384	24/18639	0.166666666666667	0.708599452554745	0.850465727399507	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	4/4384	24/18639	0.166666666666667	0.708599452554745	0.850465727399507	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	4/4384	24/18639	0.166666666666667	0.708599452554745	0.850465727399507	1
GO:0004879	nuclear receptor activity	11/4384	59/18639	0.186440677966102	0.79267057404429	0.851219099831768	1
GO:0070888	E-box binding	11/4384	59/18639	0.186440677966102	0.79267057404429	0.851219099831768	1
GO:0070851	growth factor receptor binding	28/4384	139/18639	0.201438848920863	0.85643674841149	0.851903534358072	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	3/4384	19/18639	0.157894736842105	0.671304744525547	0.85907611406814	1
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/4384	19/18639	0.157894736842105	0.671304744525547	0.85907611406814	1
GO:0008381	mechanosensitive monoatomic ion channel activity	3/4384	19/18639	0.157894736842105	0.671304744525547	0.85907611406814	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/4384	19/18639	0.157894736842105	0.671304744525547	0.85907611406814	1
GO:0031420	alkali metal ion binding	3/4384	19/18639	0.157894736842105	0.671304744525547	0.85907611406814	1
GO:0042577	lipid phosphatase activity	3/4384	19/18639	0.157894736842105	0.671304744525547	0.85907611406814	1
GO:0046527	glucosyltransferase activity	3/4384	19/18639	0.157894736842105	0.671304744525547	0.85907611406814	1
GO:0070003	threonine-type peptidase activity	3/4384	19/18639	0.157894736842105	0.671304744525547	0.85907611406814	1
GO:0097001	ceramide binding	3/4384	19/18639	0.157894736842105	0.671304744525547	0.85907611406814	1
GO:0050997	quaternary ammonium group binding	7/4384	40/18639	0.175	0.744029425182482	0.862973459012758	1
GO:0015605	organophosphate ester transmembrane transporter activity	9/4384	50/18639	0.18	0.765287408759124	0.863490287921142	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	5/4384	30/18639	0.166666666666667	0.708599452554745	0.867159947016026	1
GO:0016769	transferase activity, transferring nitrogenous groups	5/4384	30/18639	0.166666666666667	0.708599452554745	0.867159947016026	1
GO:0003707	nuclear steroid receptor activity	4/4384	25/18639	0.16	0.680255474452555	0.872670012820717	1
GO:0005537	D-mannose binding	4/4384	25/18639	0.16	0.680255474452555	0.872670012820717	1
GO:0008191	metalloendopeptidase inhibitor activity	2/4384	14/18639	0.142857142857143	0.607370959332638	0.875827238449511	1
GO:0008195	phosphatidate phosphatase activity	2/4384	14/18639	0.142857142857143	0.607370959332638	0.875827238449511	1
GO:0008494	translation activator activity	2/4384	14/18639	0.142857142857143	0.607370959332638	0.875827238449511	1
GO:0008559	ABC-type xenobiotic transporter activity	2/4384	14/18639	0.142857142857143	0.607370959332638	0.875827238449511	1
GO:0015386	potassium:proton antiporter activity	2/4384	14/18639	0.142857142857143	0.607370959332638	0.875827238449511	1
GO:0015926	glucosidase activity	2/4384	14/18639	0.142857142857143	0.607370959332638	0.875827238449511	1
GO:0031404	chloride ion binding	2/4384	14/18639	0.142857142857143	0.607370959332638	0.875827238449511	1
GO:1901474	azole transmembrane transporter activity	2/4384	14/18639	0.142857142857143	0.607370959332638	0.875827238449511	1
GO:1901612	cardiolipin binding	2/4384	14/18639	0.142857142857143	0.607370959332638	0.875827238449511	1
GO:0140828	metal cation:monoatomic cation antiporter activity	7/4384	41/18639	0.170731707317073	0.72588236603169	0.879751228758332	1
GO:0008235	metalloexopeptidase activity	12/4384	66/18639	0.181818181818182	0.773017584605176	0.881341806993675	1
GO:0004033	aldo-keto reductase (NADPH) activity	6/4384	36/18639	0.166666666666667	0.708599452554745	0.881864905579777	1
GO:0004190	aspartic-type endopeptidase activity	6/4384	36/18639	0.166666666666667	0.708599452554745	0.881864905579777	1
GO:0001972	retinoic acid binding	3/4384	20/18639	0.15	0.63773950729927	0.882388392062659	1
GO:0010851	cyclase regulator activity	3/4384	20/18639	0.15	0.63773950729927	0.882388392062659	1
GO:0070325	lipoprotein particle receptor binding	5/4384	31/18639	0.161290322580645	0.68574140569814	0.885659942642859	1
GO:0072349	modified amino acid transmembrane transporter activity	5/4384	31/18639	0.161290322580645	0.68574140569814	0.885659942642859	1
GO:0008198	ferrous iron binding	4/4384	26/18639	0.153846153846154	0.654091802358226	0.891964861681148	1
GO:0030247	polysaccharide binding	4/4384	26/18639	0.153846153846154	0.654091802358226	0.891964861681148	1
GO:0005504	fatty acid binding	8/4384	47/18639	0.170212765957447	0.723676036651654	0.893198532723592	1
GO:0070001	aspartic-type peptidase activity	6/4384	37/18639	0.162162162162162	0.689448115999211	0.897524030285988	1
GO:0016829	lyase activity	40/4384	200/18639	0.2	0.850319343065693	0.898649878407264	1
GO:0004129	cytochrome-c oxidase activity	2/4384	15/18639	0.133333333333333	0.566879562043796	0.899545066899391	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/4384	15/18639	0.133333333333333	0.566879562043796	0.899545066899391	1
GO:0015929	hexosaminidase activity	2/4384	15/18639	0.133333333333333	0.566879562043796	0.899545066899391	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/4384	15/18639	0.133333333333333	0.566879562043796	0.899545066899391	1
GO:0017081	chloride channel regulator activity	2/4384	15/18639	0.133333333333333	0.566879562043796	0.899545066899391	1
GO:0033130	acetylcholine receptor binding	2/4384	15/18639	0.133333333333333	0.566879562043796	0.899545066899391	1
GO:0047372	monoacylglycerol lipase activity	2/4384	15/18639	0.133333333333333	0.566879562043796	0.899545066899391	1
GO:0015174	basic amino acid transmembrane transporter activity	3/4384	21/18639	0.142857142857143	0.607370959332638	0.902196128131905	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	10/4384	58/18639	0.172413793103448	0.733033916435943	0.904337362044894	1
GO:1901505	carbohydrate derivative transmembrane transporter activity	9/4384	53/18639	0.169811320754717	0.721969253546343	0.904916903223841	1
GO:0008194	UDP-glycosyltransferase activity	28/4384	145/18639	0.193103448275862	0.820997986408256	0.905221168197129	1
GO:0005200	structural constituent of cytoskeleton	21/4384	112/18639	0.1875	0.797174384124088	0.906908879580941	1
GO:0005126	cytokine receptor binding	56/4384	275/18639	0.203636363636364	0.865779694757797	0.907436174839966	1
GO:0005385	zinc ion transmembrane transporter activity	4/4384	27/18639	0.148148148148148	0.629866180048662	0.908643744789013	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/4384	27/18639	0.148148148148148	0.629866180048662	0.908643744789013	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	102/4384	484/18639	0.210743801652893	0.895997654883272	0.911137495442917	1
GO:0042887	amide transmembrane transporter activity	6/4384	38/18639	0.157894736842105	0.671304744525547	0.911368659599004	1
GO:0048029	monosaccharide binding	13/4384	74/18639	0.175675675675676	0.746902125665812	0.914852780318761	1
GO:0001786	phosphatidylserine binding	10/4384	59/18639	0.169491525423729	0.720609612767537	0.915177823721043	1
GO:0016835	carbon-oxygen lyase activity	14/4384	79/18639	0.177215189873418	0.753447519172133	0.915315920811361	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	5/4384	33/18639	0.151515151515152	0.644181320504313	0.916096083058615	1
GO:0050661	NADP binding	9/4384	54/18639	0.166666666666667	0.708599452554745	0.916130478920562	1
GO:0140375	immune receptor activity	30/4384	156/18639	0.192307692307692	0.817614752947782	0.916157509551839	1
GO:0008970	phospholipase A1 activity	3/4384	22/18639	0.136363636363636	0.579763188453882	0.91893730533669	1
GO:0016881	acid-amino acid ligase activity	3/4384	22/18639	0.136363636363636	0.579763188453882	0.91893730533669	1
GO:0005149	interleukin-1 receptor binding	2/4384	16/18639	0.125	0.531449589416058	0.918977901995993	1
GO:0008142	oxysterol binding	2/4384	16/18639	0.125	0.531449589416058	0.918977901995993	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/4384	16/18639	0.125	0.531449589416058	0.918977901995993	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/4384	16/18639	0.125	0.531449589416058	0.918977901995993	1
GO:0051119	sugar transmembrane transporter activity	4/4384	28/18639	0.142857142857143	0.607370959332638	0.922991778178225	1
GO:0048306	calcium-dependent protein binding	14/4384	80/18639	0.175	0.744029425182482	0.923925036137145	1
GO:0003779	actin binding	92/4384	443/18639	0.207674943566591	0.882950107923745	0.92654806422193	1
GO:0019955	cytokine binding	27/4384	144/18639	0.1875	0.797174384124088	0.929999104540871	1
GO:0005337	nucleoside transmembrane transporter activity	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0005345	purine nucleobase transmembrane transporter activity	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0008190	eukaryotic initiation factor 4E binding	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0008519	ammonium channel activity	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0031419	cobalamin binding	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0032052	bile acid binding	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0032395	MHC class II receptor activity	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0035374	chondroitin sulfate binding	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0043121	neurotrophin binding	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0043208	glycosphingolipid binding	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0070097	delta-catenin binding	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0070739	protein-glutamic acid ligase activity	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0070740	tubulin-glutamic acid ligase activity	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/4384	10/18639	0.1	0.425159671532847	0.931589377010324	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	24/4384	130/18639	0.184615384615385	0.784910162829871	0.932283724633392	1
GO:0000295	adenine nucleotide transmembrane transporter activity	3/4384	23/18639	0.130434782608696	0.554556093303713	0.933019066015428	1
GO:0005283	amino acid:sodium symporter activity	3/4384	23/18639	0.130434782608696	0.554556093303713	0.933019066015428	1
GO:0017134	fibroblast growth factor binding	3/4384	23/18639	0.130434782608696	0.554556093303713	0.933019066015428	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/4384	23/18639	0.130434782608696	0.554556093303713	0.933019066015428	1
GO:0015297	antiporter activity	25/4384	135/18639	0.185185185185185	0.787332725060827	0.933400020247383	1
GO:0008013	beta-catenin binding	19/4384	106/18639	0.179245283018868	0.76207865652114	0.933891099419329	1
GO:0015144	carbohydrate transmembrane transporter activity	6/4384	40/18639	0.15	0.63773950729927	0.934250238249379	1
GO:0016758	hexosyltransferase activity	38/4384	197/18639	0.192893401015228	0.820104950164882	0.934795231550146	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/4384	17/18639	0.117647058823529	0.500187848862173	0.934828867911873	1
GO:0016805	dipeptidase activity	2/4384	17/18639	0.117647058823529	0.500187848862173	0.934828867911873	1
GO:0038191	neuropilin binding	2/4384	17/18639	0.117647058823529	0.500187848862173	0.934828867911873	1
GO:0030170	pyridoxal phosphate binding	9/4384	56/18639	0.160714285714286	0.683292329249218	0.935200779806257	1
GO:0005416	amino acid:monoatomic cation symporter activity	4/4384	29/18639	0.137931034482759	0.586427133148754	0.935279634109733	1
GO:0099604	ligand-gated calcium channel activity	4/4384	29/18639	0.137931034482759	0.586427133148754	0.935279634109733	1
GO:0001216	DNA-binding transcription activator activity	102/4384	491/18639	0.207739307535642	0.883223757563144	0.935823659181399	1
GO:0042277	peptide binding	49/4384	249/18639	0.196787148594378	0.83665959458271	0.93735659325197	1
GO:0052689	carboxylic ester hydrolase activity	16/4384	92/18639	0.173913043478261	0.739408124404951	0.939000105304789	1
GO:0008238	exopeptidase activity	18/4384	102/18639	0.176470588235294	0.750281773293259	0.939625521885199	1
GO:0070279	vitamin B6 binding	9/4384	57/18639	0.157894736842105	0.671304744525547	0.943233536633352	1
GO:0001530	lipopolysaccharide binding	6/4384	41/18639	0.146341463414634	0.62218488517002	0.943592925590702	1
GO:0004812	aminoacyl-tRNA ligase activity	6/4384	41/18639	0.146341463414634	0.62218488517002	0.943592925590702	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	6/4384	41/18639	0.146341463414634	0.62218488517002	0.943592925590702	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/4384	24/18639	0.125	0.531449589416058	0.944812400103416	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	3/4384	24/18639	0.125	0.531449589416058	0.944812400103416	1
GO:0015149	hexose transmembrane transporter activity	3/4384	24/18639	0.125	0.531449589416058	0.944812400103416	1
GO:0030215	semaphorin receptor binding	3/4384	24/18639	0.125	0.531449589416058	0.944812400103416	1
GO:0030552	cAMP binding	3/4384	24/18639	0.125	0.531449589416058	0.944812400103416	1
GO:0055056	D-glucose transmembrane transporter activity	3/4384	24/18639	0.125	0.531449589416058	0.944812400103416	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	4/4384	30/18639	0.133333333333333	0.566879562043796	0.945759585970304	1
GO:0005496	steroid binding	19/4384	108/18639	0.175925925925926	0.747966088807786	0.945796271104699	1
GO:0005114	type II transforming growth factor beta receptor binding	1/4384	11/18639	0.0909090909090909	0.386508792302588	0.94768858637136	1
GO:0008271	secondary active sulfate transmembrane transporter activity	1/4384	11/18639	0.0909090909090909	0.386508792302588	0.94768858637136	1
GO:0015205	nucleobase transmembrane transporter activity	1/4384	11/18639	0.0909090909090909	0.386508792302588	0.94768858637136	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/4384	11/18639	0.0909090909090909	0.386508792302588	0.94768858637136	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/4384	11/18639	0.0909090909090909	0.386508792302588	0.94768858637136	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/4384	11/18639	0.0909090909090909	0.386508792302588	0.94768858637136	1
GO:0035252	UDP-xylosyltransferase activity	1/4384	11/18639	0.0909090909090909	0.386508792302588	0.94768858637136	1
GO:0042285	xylosyltransferase activity	1/4384	11/18639	0.0909090909090909	0.386508792302588	0.94768858637136	1
GO:0048185	activin binding	1/4384	11/18639	0.0909090909090909	0.386508792302588	0.94768858637136	1
GO:0048407	platelet-derived growth factor binding	1/4384	11/18639	0.0909090909090909	0.386508792302588	0.94768858637136	1
GO:0070697	activin receptor binding	1/4384	11/18639	0.0909090909090909	0.386508792302588	0.94768858637136	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/4384	11/18639	0.0909090909090909	0.386508792302588	0.94768858637136	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/4384	18/18639	0.111111111111111	0.472399635036496	0.947707458520146	1
GO:0032393	MHC class I receptor activity	2/4384	18/18639	0.111111111111111	0.472399635036496	0.947707458520146	1
GO:0070064	proline-rich region binding	2/4384	18/18639	0.111111111111111	0.472399635036496	0.947707458520146	1
GO:0098641	cadherin binding involved in cell-cell adhesion	2/4384	18/18639	0.111111111111111	0.472399635036496	0.947707458520146	1
GO:0005507	copper ion binding	10/4384	63/18639	0.158730158730159	0.674856621480709	0.948702854929384	1
GO:0000030	mannosyltransferase activity	3/4384	25/18639	0.12	0.510191605839416	0.954649998369239	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/4384	31/18639	0.129032258064516	0.548593124558512	0.954663236833629	1
GO:0022829	wide pore channel activity	5/4384	37/18639	0.135135135135135	0.574540096666009	0.956336040900448	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/4384	19/18639	0.105263157894737	0.447536496350365	0.9581346755145	1
GO:0022821	solute:potassium antiporter activity	2/4384	19/18639	0.105263157894737	0.447536496350365	0.9581346755145	1
GO:0141147	intracellularly calcium-gated channel activity	2/4384	19/18639	0.105263157894737	0.447536496350365	0.9581346755145	1
GO:0008237	metallopeptidase activity	34/4384	184/18639	0.184782608695652	0.78562113218026	0.959198565486458	1
GO:0004859	phospholipase inhibitor activity	1/4384	12/18639	0.0833333333333333	0.354299726277372	0.959999797309086	1
GO:0005025	transforming growth factor beta receptor activity, type I	1/4384	12/18639	0.0833333333333333	0.354299726277372	0.959999797309086	1
GO:0005026	transforming growth factor beta receptor activity, type II	1/4384	12/18639	0.0833333333333333	0.354299726277372	0.959999797309086	1
GO:0015269	calcium-activated potassium channel activity	1/4384	12/18639	0.0833333333333333	0.354299726277372	0.959999797309086	1
GO:0016208	AMP binding	1/4384	12/18639	0.0833333333333333	0.354299726277372	0.959999797309086	1
GO:0016361	activin receptor activity, type I	1/4384	12/18639	0.0833333333333333	0.354299726277372	0.959999797309086	1
GO:0016362	activin receptor activity, type II	1/4384	12/18639	0.0833333333333333	0.354299726277372	0.959999797309086	1
GO:0017002	activin receptor activity	1/4384	12/18639	0.0833333333333333	0.354299726277372	0.959999797309086	1
GO:0070410	co-SMAD binding	1/4384	12/18639	0.0833333333333333	0.354299726277372	0.959999797309086	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	15/4384	91/18639	0.164835164835165	0.700812645383813	0.960962754507251	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/4384	32/18639	0.125	0.531449589416058	0.962200539297594	1
GO:0005227	calcium-activated cation channel activity	3/4384	26/18639	0.115384615384615	0.490568851768669	0.962826320545946	1
GO:0015145	monosaccharide transmembrane transporter activity	3/4384	26/18639	0.115384615384615	0.490568851768669	0.962826320545946	1
GO:0015216	purine nucleotide transmembrane transporter activity	3/4384	26/18639	0.115384615384615	0.490568851768669	0.962826320545946	1
GO:0000146	microfilament motor activity	5/4384	38/18639	0.131578947368421	0.559420620437956	0.963149280491575	1
GO:0003730	mRNA 3'-UTR binding	50/4384	262/18639	0.190839694656489	0.811373418955814	0.964799326564225	1
GO:0001614	purinergic nucleotide receptor activity	2/4384	20/18639	0.1	0.425159671532847	0.966550929231371	1
GO:0016502	nucleotide receptor activity	2/4384	20/18639	0.1	0.425159671532847	0.966550929231371	1
GO:0048020	CCR chemokine receptor binding	7/4384	50/18639	0.14	0.595223540145985	0.967030506937205	1
GO:0016836	hydro-lyase activity	9/4384	61/18639	0.147540983606557	0.627284761277971	0.967261050090447	1
GO:0002161	aminoacyl-tRNA editing activity	1/4384	13/18639	0.0769230769230769	0.327045901179113	0.969414136096704	1
GO:0005172	vascular endothelial growth factor receptor binding	1/4384	13/18639	0.0769230769230769	0.327045901179113	0.969414136096704	1
GO:0005542	folic acid binding	1/4384	13/18639	0.0769230769230769	0.327045901179113	0.969414136096704	1
GO:0008035	high-density lipoprotein particle binding	1/4384	13/18639	0.0769230769230769	0.327045901179113	0.969414136096704	1
GO:0030955	potassium ion binding	1/4384	13/18639	0.0769230769230769	0.327045901179113	0.969414136096704	1
GO:0070123	transforming growth factor beta receptor activity, type III	1/4384	13/18639	0.0769230769230769	0.327045901179113	0.969414136096704	1
GO:0070700	BMP receptor binding	1/4384	13/18639	0.0769230769230769	0.327045901179113	0.969414136096704	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/4384	13/18639	0.0769230769230769	0.327045901179113	0.969414136096704	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/4384	13/18639	0.0769230769230769	0.327045901179113	0.969414136096704	1
GO:1901338	catecholamine binding	1/4384	13/18639	0.0769230769230769	0.327045901179113	0.969414136096704	1
GO:0004364	glutathione transferase activity	3/4384	27/18639	0.111111111111111	0.472399635036496	0.969599142515563	1
GO:0016597	amino acid binding	7/4384	51/18639	0.137254901960784	0.583552490339201	0.971773414567508	1
GO:0001846	opsonin binding	2/4384	21/18639	0.0952380952380952	0.404913972888425	0.973325118820789	1
GO:0008373	sialyltransferase activity	2/4384	21/18639	0.0952380952380952	0.404913972888425	0.973325118820789	1
GO:0051428	peptide hormone receptor binding	2/4384	21/18639	0.0952380952380952	0.404913972888425	0.973325118820789	1
GO:0061891	calcium ion sensor activity	2/4384	21/18639	0.0952380952380952	0.404913972888425	0.973325118820789	1
GO:0003777	microtubule motor activity	10/4384	68/18639	0.147058823529412	0.625234811077716	0.973849224090999	1
GO:0090482	vitamin transmembrane transporter activity	4/4384	34/18639	0.117647058823529	0.500187848862173	0.973908217626674	1
GO:0004222	metalloendopeptidase activity	18/4384	110/18639	0.163636363636364	0.695715826144658	0.974391783353679	1
GO:0033293	monocarboxylic acid binding	12/4384	79/18639	0.151898734177215	0.6458121592904	0.9748911696287	1
GO:0045499	chemorepellent activity	3/4384	28/18639	0.107142857142857	0.455528219499479	0.975192026236044	1
GO:0050698	proteoglycan sulfotransferase activity	3/4384	28/18639	0.107142857142857	0.455528219499479	0.975192026236044	1
GO:0051959	dynein light intermediate chain binding	3/4384	28/18639	0.107142857142857	0.455528219499479	0.975192026236044	1
GO:0005080	protein kinase C binding	7/4384	52/18639	0.134615384615385	0.572330327063447	0.97588296490709	1
GO:0005313	L-glutamate transmembrane transporter activity	1/4384	14/18639	0.0714285714285714	0.303685479666319	0.976613128223412	1
GO:0005344	oxygen carrier activity	1/4384	14/18639	0.0714285714285714	0.303685479666319	0.976613128223412	1
GO:0019763	immunoglobulin receptor activity	1/4384	14/18639	0.0714285714285714	0.303685479666319	0.976613128223412	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/4384	14/18639	0.0714285714285714	0.303685479666319	0.976613128223412	1
GO:0042813	Wnt receptor activity	1/4384	14/18639	0.0714285714285714	0.303685479666319	0.976613128223412	1
GO:0043176	amine binding	1/4384	14/18639	0.0714285714285714	0.303685479666319	0.976613128223412	1
GO:0098821	BMP receptor activity	1/4384	14/18639	0.0714285714285714	0.303685479666319	0.976613128223412	1
GO:0004175	endopeptidase activity	79/4384	405/18639	0.195061728395062	0.829323803730738	0.978190931315285	1
GO:0016229	steroid dehydrogenase activity	4/4384	35/18639	0.114285714285714	0.48589676746611	0.978393266651076	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	22/4384	132/18639	0.166666666666667	0.708599452554745	0.978741970258542	1
GO:0033691	sialic acid binding	2/4384	22/18639	0.0909090909090909	0.386508792302588	0.978763900169198	1
GO:0140784	metal ion sensor activity	2/4384	22/18639	0.0909090909090909	0.386508792302588	0.978763900169198	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	20/4384	122/18639	0.163934426229508	0.696983068086634	0.979068422726654	1
GO:0072341	modified amino acid binding	14/4384	91/18639	0.153846153846154	0.654091802358226	0.979122130004618	1
GO:0005544	calcium-dependent phospholipid binding	7/4384	53/18639	0.132075471698113	0.561531641647156	0.979434569390967	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	10/4384	70/18639	0.142857142857143	0.607370959332638	0.980280670587643	1
GO:0016782	transferase activity, transferring sulphur-containing groups	10/4384	70/18639	0.142857142857143	0.607370959332638	0.980280670587643	1
GO:0015459	potassium channel regulator activity	8/4384	59/18639	0.135593220338983	0.576487690214029	0.980507295754737	1
GO:0015101	organic cation transmembrane transporter activity	12/4384	81/18639	0.148148148148148	0.629866180048662	0.980748778512238	1
GO:0038187	pattern recognition receptor activity	6/4384	48/18639	0.125	0.531449589416058	0.981913810482398	1
GO:0004089	carbonate dehydratase activity	1/4384	15/18639	0.0666666666666667	0.283439781021898	0.982117989746556	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/4384	15/18639	0.0666666666666667	0.283439781021898	0.982117989746556	1
GO:0010181	FMN binding	1/4384	15/18639	0.0666666666666667	0.283439781021898	0.982117989746556	1
GO:0015116	sulfate transmembrane transporter activity	1/4384	15/18639	0.0666666666666667	0.283439781021898	0.982117989746556	1
GO:0015250	water channel activity	1/4384	15/18639	0.0666666666666667	0.283439781021898	0.982117989746556	1
GO:0031005	filamin binding	1/4384	15/18639	0.0666666666666667	0.283439781021898	0.982117989746556	1
GO:0034483	heparan sulfate sulfotransferase activity	1/4384	15/18639	0.0666666666666667	0.283439781021898	0.982117989746556	1
GO:0045504	dynein heavy chain binding	1/4384	15/18639	0.0666666666666667	0.283439781021898	0.982117989746556	1
GO:0140161	monocarboxylate:sodium symporter activity	1/4384	15/18639	0.0666666666666667	0.283439781021898	0.982117989746556	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/4384	36/18639	0.111111111111111	0.472399635036496	0.982143865995149	1
GO:0004602	glutathione peroxidase activity	2/4384	23/18639	0.0869565217391304	0.369704062202475	0.983120551040986	1
GO:0005212	structural constituent of eye lens	2/4384	23/18639	0.0869565217391304	0.369704062202475	0.983120551040986	1
GO:0001968	fibronectin binding	3/4384	30/18639	0.1	0.425159671532847	0.983579270726208	1
GO:0022839	monoatomic ion-gated channel activity	3/4384	30/18639	0.1	0.425159671532847	0.983579270726208	1
GO:0033612	receptor serine/threonine kinase binding	3/4384	30/18639	0.1	0.425159671532847	0.983579270726208	1
GO:0004620	phospholipase activity	17/4384	109/18639	0.155963302752294	0.663093065693431	0.984250233965302	1
GO:0015078	proton transmembrane transporter activity	32/4384	185/18639	0.172972972972973	0.735411323732492	0.984344863745551	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	13/4384	88/18639	0.147727272727273	0.628076787491705	0.984533263665637	1
GO:0030551	cyclic nucleotide binding	4/4384	37/18639	0.108108108108108	0.459632077332807	0.985272087218749	1
GO:0005024	transforming growth factor beta receptor activity	1/4384	16/18639	0.0625	0.265724794708029	0.986327328929927	1
GO:0015378	sodium:chloride symporter activity	1/4384	16/18639	0.0625	0.265724794708029	0.986327328929927	1
GO:0016722	oxidoreductase activity, acting on metal ions	1/4384	16/18639	0.0625	0.265724794708029	0.986327328929927	1
GO:0055102	lipase inhibitor activity	1/4384	16/18639	0.0625	0.265724794708029	0.986327328929927	1
GO:0004622	lysophospholipase activity	2/4384	24/18639	0.0833333333333333	0.354299726277372	0.986603110217129	1
GO:0004806	triacylglycerol lipase activity	2/4384	24/18639	0.0833333333333333	0.354299726277372	0.986603110217129	1
GO:0005540	hyaluronic acid binding	2/4384	24/18639	0.0833333333333333	0.354299726277372	0.986603110217129	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/4384	24/18639	0.0833333333333333	0.354299726277372	0.986603110217129	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/4384	24/18639	0.0833333333333333	0.354299726277372	0.986603110217129	1
GO:0005452	solute:inorganic anion antiporter activity	3/4384	31/18639	0.0967741935483871	0.411444843418884	0.986677417214699	1
GO:0170055	lipid transmembrane transporter activity	7/4384	56/18639	0.125	0.531449589416058	0.987389316728972	1
GO:0016247	channel regulator activity	28/4384	168/18639	0.166666666666667	0.708599452554745	0.988342948833477	1
GO:0001848	complement binding	2/4384	25/18639	0.08	0.340127737226277	0.989381641682163	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/4384	25/18639	0.08	0.340127737226277	0.989381641682163	1
GO:0008484	sulfuric ester hydrolase activity	1/4384	17/18639	0.0588235294117647	0.250093924431086	0.989545982743555	1
GO:0030169	low-density lipoprotein particle binding	1/4384	17/18639	0.0588235294117647	0.250093924431086	0.989545982743555	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/4384	17/18639	0.0588235294117647	0.250093924431086	0.989545982743555	1
GO:0045236	CXCR chemokine receptor binding	1/4384	17/18639	0.0588235294117647	0.250093924431086	0.989545982743555	1
GO:0070492	oligosaccharide binding	1/4384	17/18639	0.0588235294117647	0.250093924431086	0.989545982743555	1
GO:0141108	transporter regulator activity	28/4384	170/18639	0.164705882352941	0.700262988407042	0.990535407098916	1
GO:0099106	ion channel regulator activity	26/4384	160/18639	0.1625	0.690884466240876	0.990701923033056	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	6/4384	52/18639	0.115384615384615	0.490568851768669	0.990961464802434	1
GO:0004180	carboxypeptidase activity	5/4384	46/18639	0.108695652173913	0.462130077753094	0.991206998917068	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/4384	18/18639	0.0555555555555556	0.236199817518248	0.992007072403756	1
GO:0005372	water transmembrane transporter activity	1/4384	18/18639	0.0555555555555556	0.236199817518248	0.992007072403756	1
GO:0015373	monoatomic anion:sodium symporter activity	1/4384	18/18639	0.0555555555555556	0.236199817518248	0.992007072403756	1
GO:0016854	racemase and epimerase activity	1/4384	18/18639	0.0555555555555556	0.236199817518248	0.992007072403756	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/4384	18/18639	0.0555555555555556	0.236199817518248	0.992007072403756	1
GO:0034185	apolipoprotein binding	1/4384	18/18639	0.0555555555555556	0.236199817518248	0.992007072403756	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/4384	18/18639	0.0555555555555556	0.236199817518248	0.992007072403756	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	7/4384	59/18639	0.11864406779661	0.504426728937276	0.992386314213057	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	3/4384	34/18639	0.0882352941176471	0.375140886646629	0.992955087541989	1
GO:0001540	amyloid-beta binding	11/4384	83/18639	0.132530120481928	0.56346462492305	0.993368580107019	1
GO:0042379	chemokine receptor binding	9/4384	72/18639	0.125	0.531449589416058	0.993797467100169	1
GO:0005520	insulin-like growth factor binding	1/4384	19/18639	0.0526315789473684	0.223768248175182	0.993888872230936	1
GO:0030506	ankyrin binding	1/4384	19/18639	0.0526315789473684	0.223768248175182	0.993888872230936	1
GO:0034987	immunoglobulin receptor binding	1/4384	19/18639	0.0526315789473684	0.223768248175182	0.993888872230936	1
GO:0042834	peptidoglycan binding	1/4384	19/18639	0.0526315789473684	0.223768248175182	0.993888872230936	1
GO:0043395	heparan sulfate proteoglycan binding	1/4384	19/18639	0.0526315789473684	0.223768248175182	0.993888872230936	1
GO:0005343	organic acid:sodium symporter activity	3/4384	35/18639	0.0857142857142857	0.364422575599583	0.994320258250512	1
GO:0098632	cell-cell adhesion mediator activity	6/4384	55/18639	0.109090909090909	0.463810550763106	0.994721426198244	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	29/4384	181/18639	0.160220994475138	0.681195053837158	0.994972473991056	1
GO:0015171	amino acid transmembrane transporter activity	14/4384	102/18639	0.137254901960784	0.583552490339201	0.995219348998775	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/4384	20/18639	0.05	0.212579835766423	0.995327711336177	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/4384	20/18639	0.05	0.212579835766423	0.995327711336177	1
GO:0030627	pre-mRNA 5'-splice site binding	1/4384	20/18639	0.05	0.212579835766423	0.995327711336177	1
GO:0004181	metallocarboxypeptidase activity	2/4384	29/18639	0.0689655172413793	0.293213566574377	0.995859016840015	1
GO:0051861	glycolipid binding	2/4384	29/18639	0.0689655172413793	0.293213566574377	0.995859016840015	1
GO:0030280	structural constituent of skin epidermis	3/4384	37/18639	0.0810810810810811	0.344724057999605	0.996323242628845	1
GO:0042805	actinin binding	3/4384	37/18639	0.0810810810810811	0.344724057999605	0.996323242628845	1
GO:0004601	peroxidase activity	6/4384	57/18639	0.105263157894737	0.447536496350365	0.996339784349022	1
GO:0015125	bile acid transmembrane transporter activity	1/4384	21/18639	0.0476190476190476	0.202456986444213	0.996427840961946	1
GO:0048019	receptor antagonist activity	2/4384	30/18639	0.0666666666666667	0.283439781021898	0.99673614156243	1
GO:0005506	iron ion binding	23/4384	154/18639	0.149350649350649	0.634978730211394	0.996928563719848	1
GO:0008009	chemokine activity	4/4384	45/18639	0.0888888888888889	0.377919708029197	0.997029657328714	1
GO:0005109	frizzled binding	3/4384	38/18639	0.0789473684210526	0.335652372262774	0.997047397394479	1
GO:0005501	retinoid binding	3/4384	38/18639	0.0789473684210526	0.335652372262774	0.997047397394479	1
GO:0019840	isoprenoid binding	3/4384	38/18639	0.0789473684210526	0.335652372262774	0.997047397394479	1
GO:0015377	chloride:monoatomic cation symporter activity	1/4384	22/18639	0.0454545454545455	0.193254396151294	0.997268980999696	1
GO:0033038	bitter taste receptor activity	1/4384	22/18639	0.0454545454545455	0.193254396151294	0.997268980999696	1
GO:0017147	Wnt-protein binding	2/4384	31/18639	0.0645161290322581	0.274296562279256	0.997429846689859	1
GO:0047499	calcium-independent phospholipase A2 activity	2/4384	31/18639	0.0645161290322581	0.274296562279256	0.997429846689859	1
GO:0046943	carboxylic acid transmembrane transporter activity	29/4384	188/18639	0.154255319148936	0.655831408215561	0.997707714622901	1
GO:0016298	lipase activity	18/4384	130/18639	0.138461538461538	0.588682622122403	0.997904920102882	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/4384	23/18639	0.0434782608695652	0.184852031101238	0.997912091452365	1
GO:0099186	structural constituent of postsynapse	1/4384	23/18639	0.0434782608695652	0.184852031101238	0.997912091452365	1
GO:0005342	organic acid transmembrane transporter activity	29/4384	189/18639	0.153439153439153	0.652361400764685	0.997957905703371	1
GO:0042910	xenobiotic transmembrane transporter activity	2/4384	32/18639	0.0625	0.265724794708029	0.997977869266936	1
GO:0047498	calcium-dependent phospholipase A2 activity	2/4384	32/18639	0.0625	0.265724794708029	0.997977869266936	1
GO:0071813	lipoprotein particle binding	2/4384	32/18639	0.0625	0.265724794708029	0.997977869266936	1
GO:0071814	protein-lipid complex binding	2/4384	32/18639	0.0625	0.265724794708029	0.997977869266936	1
GO:0016209	antioxidant activity	10/4384	86/18639	0.116279069767442	0.494371711084705	0.998344449469219	1
GO:0050431	transforming growth factor beta binding	1/4384	24/18639	0.0416666666666667	0.177149863138686	0.998403786288679	1
GO:0017080	sodium channel regulator activity	3/4384	41/18639	0.0731707317073171	0.31109244258501	0.99848151039132	1
GO:0031406	carboxylic acid binding	28/4384	187/18639	0.149732620320856	0.636602716733674	0.998609630420284	1
GO:0005251	delayed rectifier potassium channel activity	1/4384	25/18639	0.04	0.170063868613139	0.998779708980618	1
GO:0015271	outward rectifier potassium channel activity	1/4384	25/18639	0.04	0.170063868613139	0.998779708980618	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/4384	25/18639	0.04	0.170063868613139	0.998779708980618	1
GO:0042056	chemoattractant activity	3/4384	42/18639	0.0714285714285714	0.303685479666319	0.99878600602221	1
GO:1901682	sulfur compound transmembrane transporter activity	6/4384	63/18639	0.0952380952380952	0.404913972888425	0.998818549215011	1
GO:0043177	organic acid binding	28/4384	189/18639	0.148148148148148	0.629866180048662	0.998908258725078	1
GO:0061134	peptidase regulator activity	35/4384	226/18639	0.154867256637168	0.658433119630515	0.998938382773487	1
GO:0004623	phospholipase A2 activity	2/4384	35/18639	0.0571428571428571	0.242948383733055	0.999019847510683	1
GO:0019865	immunoglobulin binding	1/4384	26/18639	0.0384615384615385	0.163522950589556	0.999067113935435	1
GO:0015085	calcium ion transmembrane transporter activity	20/4384	147/18639	0.136054421768707	0.578448532697751	0.999075303098212	1
GO:0005518	collagen binding	7/4384	72/18639	0.0972222222222222	0.413349680656934	0.999263494736435	1
GO:0005104	fibroblast growth factor receptor binding	1/4384	27/18639	0.037037037037037	0.157466545012165	0.999286840605346	1
GO:0015252	proton channel activity	1/4384	27/18639	0.037037037037037	0.157466545012165	0.999286840605346	1
GO:0019842	vitamin binding	20/4384	150/18639	0.133333333333333	0.566879562043796	0.999390039927802	1
GO:0043394	proteoglycan binding	2/4384	37/18639	0.0540540540540541	0.229816038666404	0.999397347364197	1
GO:0008146	sulfotransferase activity	4/4384	53/18639	0.0754716981132075	0.320875223798375	0.999449636699312	1
GO:0005242	inward rectifier potassium channel activity	1/4384	28/18639	0.0357142857142857	0.15184273983316	0.999454823132004	1
GO:0008527	taste receptor activity	1/4384	28/18639	0.0357142857142857	0.15184273983316	0.999454823132004	1
GO:0051393	alpha-actinin binding	1/4384	28/18639	0.0357142857142857	0.15184273983316	0.999454823132004	1
GO:0019838	growth factor binding	17/4384	136/18639	0.125	0.531449589416058	0.999603408058552	1
GO:0005262	calcium channel activity	16/4384	131/18639	0.122137404580153	0.519278988131721	0.999647303335934	1
GO:0098631	cell adhesion mediator activity	7/4384	76/18639	0.0921052631578947	0.391594434306569	0.999655305780788	1
GO:0098918	structural constituent of synapse	1/4384	30/18639	0.0333333333333333	0.141719890510949	0.999681420758492	1
GO:0005178	integrin binding	21/4384	161/18639	0.130434782608696	0.554556093303713	0.999715340375577	1
GO:0005253	monoatomic anion channel activity	11/4384	103/18639	0.106796116504854	0.454054018141875	0.99973901337218	1
GO:0061135	endopeptidase regulator activity	25/4384	184/18639	0.135869565217391	0.577662597191368	0.999742247487791	1
GO:0008227	G protein-coupled amine receptor activity	2/4384	41/18639	0.0487804878048781	0.20739496172334	0.99977384488317	1
GO:0015106	bicarbonate transmembrane transporter activity	1/4384	32/18639	0.03125	0.132862397354015	0.999813847548753	1
GO:0033218	amide binding	36/4384	247/18639	0.145748987854251	0.619665918023582	0.999832753748215	1
GO:0042923	neuropeptide binding	1/4384	33/18639	0.0303030303030303	0.128836264100863	0.999857706975112	1
GO:0030547	signaling receptor inhibitor activity	2/4384	44/18639	0.0454545454545455	0.193254396151294	0.999892176452634	1
GO:0008514	organic anion transmembrane transporter activity	39/4384	269/18639	0.144981412639405	0.616402497761376	0.999919374482194	1
GO:0022804	active transmembrane transporter activity	75/4384	457/18639	0.164113785557987	0.697745631618457	0.999934519933576	1
GO:0099095	ligand-gated monoatomic anion channel activity	2/4384	47/18639	0.0425531914893617	0.180919009162914	0.999948808023437	1
GO:0015370	solute:sodium symporter activity	6/4384	79/18639	0.0759493670886076	0.3229060796452	0.999952084671622	1
GO:0030246	carbohydrate binding	40/4384	280/18639	0.142857142857143	0.607370959332638	0.999959773842007	1
GO:0042562	hormone binding	8/4384	94/18639	0.0851063829787234	0.361838018325827	0.999961392623489	1
GO:0015294	solute:monoatomic cation symporter activity	11/4384	116/18639	0.0948275862068965	0.403168654039768	0.99997420139203	1
GO:0071855	neuropeptide receptor binding	1/4384	40/18639	0.025	0.106289917883212	0.999978313669291	1
GO:0005010	insulin-like growth factor receptor activity	2/4384	51/18639	0.0392156862745098	0.166729282954058	0.99998114744077	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	3/4384	60/18639	0.05	0.212579835766423	0.999981173380116	1
GO:0015291	secondary active transmembrane transporter activity	40/4384	287/18639	0.139372822299652	0.592557033495257	0.999983380767548	1
GO:0008307	structural constituent of muscle	1/4384	42/18639	0.0238095238095238	0.101228493222106	0.99998733242706	1
GO:0005003	ephrin receptor activity	2/4384	53/18639	0.0377358490566038	0.160437611899187	0.999988584306325	1
GO:0005005	transmembrane-ephrin receptor activity	2/4384	53/18639	0.0377358490566038	0.160437611899187	0.999988584306325	1
GO:0015293	symporter activity	15/4384	146/18639	0.102739726027397	0.436807881711829	0.999988629554236	1
GO:0005245	voltage-gated calcium channel activity	1/4384	43/18639	0.0232558139534884	0.0988743422169411	0.999990318642028	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/4384	44/18639	0.0227272727272727	0.096627198075647	0.999992601018526	1
GO:0004866	endopeptidase inhibitor activity	17/4384	161/18639	0.105590062111801	0.448926361245863	0.999992709784703	1
GO:0038024	cargo receptor activity	3/4384	65/18639	0.0461538461538462	0.196227540707468	0.999994285903065	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/4384	46/18639	0.0217391304347826	0.0924260155506188	0.999995678628056	1
GO:0005254	chloride channel activity	5/4384	83/18639	0.0602409638554217	0.256120284055932	0.99999594730475	1
GO:0008188	neuropeptide receptor activity	1/4384	48/18639	0.0208333333333333	0.0885749315693431	0.99999747627209	1
GO:0003823	antigen binding	18/4384	174/18639	0.103448275862069	0.439820349861566	0.999997706015371	1
GO:0008509	monoatomic anion transmembrane transporter activity	14/4384	149/18639	0.0939597315436242	0.399478886004017	0.999997832994476	1
GO:0019199	transmembrane receptor protein kinase activity	4/4384	78/18639	0.0512820512820513	0.218030600786075	0.999997990870745	1
GO:0005004	GPI-linked ephrin receptor activity	1/4384	49/18639	0.0204081632653061	0.0867672799046626	0.99999807140001	1
GO:0005008	hepatocyte growth factor receptor activity	1/4384	49/18639	0.0204081632653061	0.0867672799046626	0.99999807140001	1
GO:0005009	insulin receptor activity	1/4384	49/18639	0.0204081632653061	0.0867672799046626	0.99999807140001	1
GO:0005011	macrophage colony-stimulating factor receptor activity	1/4384	49/18639	0.0204081632653061	0.0867672799046626	0.99999807140001	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/4384	49/18639	0.0204081632653061	0.0867672799046626	0.99999807140001	1
GO:0005020	stem cell factor receptor activity	1/4384	49/18639	0.0204081632653061	0.0867672799046626	0.99999807140001	1
GO:0008288	boss receptor activity	1/4384	49/18639	0.0204081632653061	0.0867672799046626	0.99999807140001	1
GO:0036332	placental growth factor receptor activity	1/4384	49/18639	0.0204081632653061	0.0867672799046626	0.99999807140001	1
GO:0038062	protein tyrosine kinase collagen receptor activity	1/4384	49/18639	0.0204081632653061	0.0867672799046626	0.99999807140001	1
GO:0060175	brain-derived neurotrophic factor receptor activity	1/4384	49/18639	0.0204081632653061	0.0867672799046626	0.99999807140001	1
GO:0030414	peptidase inhibitor activity	17/4384	169/18639	0.100591715976331	0.427675409234225	0.99999814774781	1
GO:0008236	serine-type peptidase activity	21/4384	194/18639	0.108247422680412	0.460224386710813	0.99999823780668	1
GO:0004252	serine-type endopeptidase activity	18/4384	176/18639	0.102272727272727	0.434822391340411	0.999998370522395	1
GO:0005006	epidermal growth factor receptor activity	1/4384	50/18639	0.02	0.0850319343065694	0.999998526213477	1
GO:0005007	fibroblast growth factor receptor activity	1/4384	50/18639	0.02	0.0850319343065694	0.999998526213477	1
GO:0005017	platelet-derived growth factor receptor activity	1/4384	50/18639	0.02	0.0850319343065694	0.999998526213477	1
GO:0005019	platelet-derived growth factor beta-receptor activity	1/4384	50/18639	0.02	0.0850319343065694	0.999998526213477	1
GO:0005021	vascular endothelial growth factor receptor activity	1/4384	51/18639	0.0196078431372549	0.0833646414770288	0.999998873788931	1
GO:0005030	neurotrophin receptor activity	1/4384	51/18639	0.0196078431372549	0.0833646414770288	0.999998873788931	1
GO:0017171	serine hydrolase activity	21/4384	198/18639	0.106060606060606	0.450926924353019	0.999999091543064	1
GO:0017046	peptide hormone binding	1/4384	53/18639	0.0188679245283019	0.0802188059495937	0.999999342389742	1
GO:0038064	collagen receptor activity	1/4384	53/18639	0.0188679245283019	0.0802188059495937	0.999999342389742	1
GO:0001664	G protein-coupled receptor binding	37/4384	297/18639	0.124579124579125	0.529660196859102	0.999999565221907	1
GO:0016500	protein-hormone receptor activity	2/4384	67/18639	0.0298507462686567	0.126913334785924	0.999999670326712	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/4384	56/18639	0.0178571428571429	0.0759213699165798	0.999999706615163	1
GO:0004867	serine-type endopeptidase inhibitor activity	5/4384	95/18639	0.0526315789473684	0.223768248175182	0.999999729034546	1
GO:0020037	heme binding	11/4384	142/18639	0.0774647887323944	0.329349041328261	0.999999823708108	1
GO:1901681	sulfur compound binding	32/4384	275/18639	0.116363636363636	0.494731254147313	0.999999845544955	1
GO:0046906	tetrapyrrole binding	12/4384	152/18639	0.0789473684210526	0.335652372262774	0.999999903277458	1
GO:0015103	inorganic anion transmembrane transporter activity	13/4384	165/18639	0.0787878787878788	0.334974286662243	0.999999970689268	1
GO:0015108	chloride transmembrane transporter activity	7/4384	121/18639	0.0578512396694215	0.245960140556192	0.999999970799594	1
GO:0004497	monooxygenase activity	5/4384	106/18639	0.0471698113207547	0.200547014873984	0.999999978541076	1
GO:0005249	voltage-gated potassium channel activity	4/4384	98/18639	0.0408163265306122	0.173534559809325	0.99999998213423	1
GO:0005125	cytokine activity	23/4384	234/18639	0.0982905982905983	0.417891984839978	0.999999983652627	1
GO:0098960	postsynaptic neurotransmitter receptor activity	1/4384	69/18639	0.0144927536231884	0.0616173437004126	0.999999991134165	1
GO:0015081	sodium ion transmembrane transporter activity	12/4384	164/18639	0.0731707317073171	0.31109244258501	0.99999999122875	1
GO:0099094	ligand-gated monoatomic cation channel activity	7/4384	136/18639	0.0514705882352941	0.2188321838772	0.99999999897943	1
GO:0005244	voltage-gated monoatomic ion channel activity	11/4384	173/18639	0.0635838150289017	0.270332739124931	0.999999999705054	1
GO:0022832	voltage-gated channel activity	11/4384	175/18639	0.0628571428571429	0.267243222106361	0.999999999807257	1
GO:0030594	neurotransmitter receptor activity	2/4384	97/18639	0.0206185567010309	0.0876617879449168	0.999999999854734	1
GO:0008201	heparin binding	10/4384	172/18639	0.0581395348837209	0.247185855542353	0.999999999929696	1
GO:0005179	hormone activity	5/4384	132/18639	0.0378787878787879	0.161045330126078	0.999999999954386	1
GO:0005267	potassium channel activity	4/4384	124/18639	0.032258064516129	0.137148281139628	0.999999999967966	1
GO:0001653	peptide receptor activity	4/4384	128/18639	0.03125	0.132862397354015	0.999999999988057	1
GO:0008528	G protein-coupled peptide receptor activity	3/4384	122/18639	0.0245901639344262	0.104547460212995	0.999999999995892	1
GO:0015079	potassium ion transmembrane transporter activity	7/4384	160/18639	0.04375	0.18600735629562	0.999999999995901	1
GO:0022843	voltage-gated monoatomic cation channel activity	5/4384	143/18639	0.034965034965035	0.148657227808688	0.999999999996797	1
GO:0008083	growth factor activity	7/4384	162/18639	0.0432098765432099	0.18371096918086	0.99999999999743	1
GO:0005539	glycosaminoglycan binding	17/4384	242/18639	0.0702479338842975	0.298665884961091	0.999999999998319	1
GO:0015276	ligand-gated monoatomic ion channel activity	9/4384	186/18639	0.0483870967741935	0.205722421709442	0.999999999999487	1
GO:0022834	ligand-gated channel activity	9/4384	188/18639	0.0478723404255319	0.203533885308278	0.999999999999675	1
GO:0005549	odorant binding	1/4384	111/18639	0.00900900900900901	0.0383026731110673	0.999999999999893	1
GO:0046873	metal ion transmembrane transporter activity	46/4384	450/18639	0.102222222222222	0.434607664233577	0.999999999999933	1
GO:0004984	olfactory receptor activity	2/4384	419/18639	0.00477326968973747	0.0202940177342648	1	1
GO:0005201	extracellular matrix structural constituent	1/4384	168/18639	0.00595238095238095	0.0253071233055266	1	1
GO:0005216	monoatomic ion channel activity	35/4384	448/18639	0.078125	0.332155993385036	1	1
GO:0005261	monoatomic cation channel activity	23/4384	341/18639	0.0674486803519062	0.286764587837404	1	1
GO:0022836	gated channel activity	19/4384	318/18639	0.059748427672956	0.25402621884038	1	1
GO:0030371	translation repressor activity	8/4384	329/18639	0.0243161094224924	0.103382290950236	1	1
GO:0045182	translation regulator activity	13/4384	356/18639	0.0365168539325843	0.155254936233905	1	1