ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0019787	ubiquitin-like protein transferase activity	219/5085	479/18639	0.457202505219207	1.6758697138212	1.80504122508498e-18	2.39348466446268e-15
GO:0140097	catalytic activity, acting on DNA	164/5085	336/18639	0.488095238095238	1.78910661609777	2.13141728607471e-17	1.41312966066753e-14
GO:0016755	aminoacyltransferase activity	220/5085	496/18639	0.443548387096774	1.62582072509278	1.08129489199244e-16	4.77932342260659e-14
GO:0004842	ubiquitin-protein transferase activity	201/5085	449/18639	0.447661469933185	1.6408971756312	7.25284396272262e-16	2.22789539823414e-13
GO:0003712	transcription coregulator activity	217/5085	495/18639	0.438383838383838	1.60689014034147	8.40081221053599e-16	2.22789539823414e-13
GO:0003697	single-stranded DNA binding	75/5085	121/18639	0.619834710743802	2.27199590433701	1.27680112982736e-15	2.82173049691846e-13
GO:0043021	ribonucleoprotein complex binding	98/5085	177/18639	0.553672316384181	2.0294785260737	2.5727005345265e-15	4.87342986968877e-13
GO:0008094	ATP-dependent activity, acting on DNA	110/5085	210/18639	0.523809523809524	1.92001685630004	9.46550756532737e-15	1.44191534926022e-12
GO:0140104	molecular carrier activity	125/5085	249/18639	0.502008032128514	1.84010377794363	9.78675576420961e-15	1.44191534926022e-12
GO:0140098	catalytic activity, acting on RNA	174/5085	387/18639	0.449612403100775	1.64804829525966	4.02935044023365e-14	5.34291868374982e-12
GO:0016887	ATP hydrolysis activity	182/5085	417/18639	0.436450839328537	1.59980475796354	2.97468456909775e-13	3.58584703511238e-11
GO:0004386	helicase activity	85/5085	155/18639	0.548387096774194	2.01010562375107	3.67068888729275e-13	4.05611122045849e-11
GO:0140597	protein carrier chaperone	95/5085	188/18639	0.50531914893617	1.85224063264922	9.42061272112535e-12	9.60902497554786e-10
GO:0003689	DNA clamp loader activity	84/5085	160/18639	0.525	1.92438053097345	1.13365185441347e-11	1.07373025639447e-09
GO:0140713	histone chaperone activity	85/5085	164/18639	0.518292682926829	1.89979494927693	2.0858917359655e-11	1.8439282945935e-09
GO:0003713	transcription coactivator activity	118/5085	256/18639	0.4609375	1.68956028761062	7.38051259714547e-11	5.91297495286058e-09
GO:0003684	damaged DNA binding	47/5085	74/18639	0.635135135135135	2.32807940684047	7.58073711905202e-11	5.91297495286058e-09
GO:0015616	DNA translocase activity	79/5085	152/18639	0.519736842105263	1.90508849557522	8.82158108203845e-11	6.15653500778052e-09
GO:0140674	ATP-dependent histone chaperone activity	79/5085	152/18639	0.519736842105263	1.90508849557522	8.82158108203845e-11	6.15653500778052e-09
GO:0140658	ATP-dependent chromatin remodeler activity	81/5085	158/18639	0.512658227848101	1.8791419289795	1.24652398321737e-10	8.26445400873114e-09
GO:0000510	H3-H4 histone complex chaperone activity	78/5085	151/18639	0.516556291390728	1.89343022915079	1.70368668162627e-10	9.41286891598515e-09
GO:0140584	chromatin extrusion motor activity	78/5085	151/18639	0.516556291390728	1.89343022915079	1.70368668162627e-10	9.41286891598515e-09
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	78/5085	151/18639	0.516556291390728	1.89343022915079	1.70368668162627e-10	9.41286891598515e-09
GO:0140849	ATP-dependent H2AZ histone chaperone activity	78/5085	151/18639	0.516556291390728	1.89343022915079	1.70368668162627e-10	9.41286891598515e-09
GO:0003678	DNA helicase activity	46/5085	74/18639	0.621621621621622	2.27854580243961	3.46874219073924e-10	1.83982085796809e-08
GO:0061775	cohesin loader activity	78/5085	153/18639	0.509803921568627	1.86867950720111	3.84927258984422e-10	1.96312902082055e-08
GO:0031072	heat shock protein binding	69/5085	131/18639	0.526717557251908	1.93067621428089	6.32454832495552e-10	3.10605595514482e-08
GO:0061659	ubiquitin-like protein ligase activity	155/5085	372/18639	0.416666666666667	1.52728613569322	1.07167050252707e-09	5.07512530839603e-08
GO:0043022	ribosome binding	60/5085	112/18639	0.535714285714286	1.96365360303413	3.46499937030967e-09	1.58434109138987e-07
GO:0042393	histone binding	110/5085	247/18639	0.445344129554656	1.63240299523485	3.69473570088604e-09	1.63307317979163e-07
GO:0044389	ubiquitin-like protein ligase binding	136/5085	322/18639	0.422360248447205	1.54815588413126	3.98209077009288e-09	1.70330721327199e-07
GO:0008135	translation factor activity, RNA binding	48/5085	83/18639	0.578313253012048	2.11979955219106	4.59914028617301e-09	1.90576875608294e-07
GO:0016779	nucleotidyltransferase activity	69/5085	136/18639	0.507352941176471	1.8596954711088	5.04524524178591e-09	2.02727126988125e-07
GO:0180051	translation factor activity	48/5085	84/18639	0.571428571428571	2.09456384323641	7.8975163956997e-09	3.08003139432289e-07
GO:0004674	protein serine/threonine kinase activity	172/5085	433/18639	0.397228637413395	1.45603629749228	9.46685995123642e-09	3.58658751295414e-07
GO:0106310	protein serine kinase activity	147/5085	361/18639	0.407202216066482	1.49259431765254	1.74540758378772e-08	6.42891793361812e-07
GO:0061630	ubiquitin protein ligase activity	144/5085	353/18639	0.407932011331445	1.49526937250871	2.12694449440528e-08	7.62250918805785e-07
GO:0017116	single-stranded DNA helicase activity	36/5085	58/18639	0.620689655172414	2.27512969179127	3.02773204871863e-08	1.05651913068445e-06
GO:0031625	ubiquitin protein ligase binding	126/5085	302/18639	0.417218543046358	1.52930903123718	3.46415572792938e-08	1.17781294749599e-06
GO:0003688	DNA replication origin binding	15/5085	16/18639	0.9375	3.43639380530973	4.05179076373147e-08	1.34316863817698e-06
GO:0051087	protein-folding chaperone binding	66/5085	134/18639	0.492537313432836	1.80538898428213	4.79690984556407e-08	1.55139084273609e-06
GO:0070063	RNA polymerase binding	36/5085	59/18639	0.610169491525424	2.23656817159142	5.72797377199058e-08	1.80840314801417e-06
GO:0140297	DNA-binding transcription factor binding	186/5085	488/18639	0.381147540983607	1.39709125199478	8.72823627333705e-08	2.69154448801045e-06
GO:0015631	tubulin binding	152/5085	385/18639	0.394805194805195	1.44715320078152	1.06793515145799e-07	3.21836820643931e-06
GO:0003743	translation initiation factor activity	32/5085	51/18639	0.627450980392157	2.29991323963214	1.22703821073139e-07	3.61567259428851e-06
GO:0003725	double-stranded RNA binding	42/5085	75/18639	0.56	2.05267256637168	1.46587022990719e-07	4.22553027142812e-06
GO:0140142	nucleocytoplasmic carrier activity	23/5085	32/18639	0.71875	2.6345685840708	1.90738636381684e-07	5.381264507279e-06
GO:0061650	ubiquitin-like protein conjugating enzyme activity	27/5085	41/18639	0.658536585365854	2.41385711202245	2.83303847096987e-07	7.82626877605426e-06
GO:0043138	3'-5' DNA helicase activity	30/5085	48/18639	0.625	2.29092920353982	3.44541530536524e-07	9.32371570390674e-06
GO:0140030	modification-dependent protein binding	78/5085	173/18639	0.450867052023121	1.65264719422988	3.55849278836144e-07	9.43712287473454e-06
GO:0051082	unfolded protein binding	59/5085	121/18639	0.487603305785124	1.78730344474512	3.75482645949773e-07	9.76254879469411e-06
GO:0016741	transferase activity, transferring one-carbon groups	92/5085	215/18639	0.427906976744186	1.56848734307471	6.21581401535322e-07	1.57206282710438e-05
GO:0003735	structural constituent of ribosome	78/5085	175/18639	0.445714285714286	1.6337597977244	6.28350903744586e-07	1.57206282710438e-05
GO:0140662	ATP-dependent protein folding chaperone	26/5085	40/18639	0.65	2.38256637168142	6.91452711019427e-07	1.69790054594771e-05
GO:1990518	single-stranded 3'-5' DNA helicase activity	29/5085	47/18639	0.617021276595745	2.26168329881378	7.98802770827144e-07	1.92584086203053e-05
GO:0060589	nucleoside-triphosphatase regulator activity	182/5085	490/18639	0.371428571428571	1.36146649810367	9.02719973658093e-07	2.13751193762613e-05
GO:0005484	SNAP receptor activity	24/5085	36/18639	0.666666666666667	2.44365781710914	9.34545563618116e-07	2.17404810062741e-05
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	136/5085	349/18639	0.389684813753582	1.42838451200649	1.1464264478776e-06	2.62096805152706e-05
GO:0051540	metal cluster binding	41/5085	77/18639	0.532467532467532	1.95175267210665	1.25175833614402e-06	2.76662320976869e-05
GO:0030695	GTPase regulator activity	181/5085	489/18639	0.370143149284254	1.3567548002968	1.25186570577769e-06	2.76662320976869e-05
GO:0000287	magnesium ion binding	96/5085	230/18639	0.417391304347826	1.52994228549442	1.38211124214859e-06	3.00439263457219e-05
GO:0009378	four-way junction helicase activity	29/5085	48/18639	0.604166666666667	2.21456489675516	1.49214887442862e-06	3.18502810282538e-05
GO:0001098	basal transcription machinery binding	34/5085	60/18639	0.566666666666667	2.07710914454277	1.53726846591873e-06	3.18502810282538e-05
GO:0001099	basal RNA polymerase II transcription machinery binding	34/5085	60/18639	0.566666666666667	2.07710914454277	1.53726846591873e-06	3.18502810282538e-05
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	74/5085	167/18639	0.44311377245509	1.6242276508929	1.57835044829165e-06	3.20020741656227e-05
GO:0035173	histone kinase activity	139/5085	360/18639	0.386111111111111	1.41528515240905	1.59286342000837e-06	3.20020741656227e-05
GO:0140852	histone ubiquitin ligase activity	12/5085	13/18639	0.923076923076923	3.38352620830497	1.63874812766248e-06	3.24325375713499e-05
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	100/5085	243/18639	0.411522633744856	1.50843075130194	1.81620239170211e-06	3.52077876831408e-05
GO:0140857	histone H3T45 kinase activity	101/5085	246/18639	0.410569105691057	1.50493560687819	1.8320794495752e-06	3.52077876831408e-05
GO:0004518	nuclease activity	88/5085	209/18639	0.421052631578947	1.54336283185841	2.42943822118702e-06	4.13375455206433e-05
GO:0051536	iron-sulfur cluster binding	40/5085	76/18639	0.526315789473684	1.92920353982301	2.47908424534307e-06	4.13375455206433e-05
GO:0043175	RNA polymerase core enzyme binding	26/5085	42/18639	0.619047619047619	2.26911083017278	2.7186401664824e-06	4.13375455206433e-05
GO:0004676	3-phosphoinositide-dependent protein kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0004711	ribosomal protein S6 kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0035175	histone H3S10 kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0035979	histone H2AXS139 kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0044022	histone H3S28 kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0044023	histone H4S1 kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0044024	histone H2AS1 kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0044025	histone H2BS14 kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0072354	histone H3T3 kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0072371	histone H2AS121 kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0072518	Rho-dependent protein serine/threonine kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0140823	histone H2BS36 kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0140855	histone H3S57 kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0140995	histone H2A kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0140997	histone H4 kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0140998	histone H2B kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:1990244	histone H2AT120 kinase activity	100/5085	245/18639	0.408163265306122	1.49611703088315	2.80480029419882e-06	4.13375455206433e-05
GO:0141003	histone H2AX kinase activity	136/5085	354/18639	0.384180790960452	1.40820958952052	2.80571575931968e-06	4.13375455206433e-05
GO:0008168	methyltransferase activity	86/5085	204/18639	0.42156862745098	1.54525420787784	2.96298040592257e-06	4.31748573434432e-05
GO:0002039	p53 binding	37/5085	69/18639	0.536231884057971	1.96555085289214	3.27472521692503e-06	4.71987569308977e-05
GO:0061749	forked DNA-dependent helicase activity	28/5085	47/18639	0.595744680851064	2.18369421954434	3.34788142579224e-06	4.77343093612958e-05
GO:0004677	DNA-dependent protein kinase activity	100/5085	246/18639	0.40650406504065	1.49003525433484	3.47104744805058e-06	4.88288359297093e-05
GO:0008017	microtubule binding	110/5085	276/18639	0.398550724637681	1.46088239066308	3.49829518350105e-06	4.88288359297093e-05
GO:0035402	histone H3T11 kinase activity	100/5085	247/18639	0.404858299595142	1.48400272294078	4.28381165491426e-06	5.85601469527454e-05
GO:0035403	histone H3T6 kinase activity	100/5085	247/18639	0.404858299595142	1.48400272294078	4.28381165491426e-06	5.85601469527454e-05
GO:0140996	histone H3 kinase activity	136/5085	357/18639	0.380952380952381	1.39637589549094	4.70055911441713e-06	6.35175426213998e-05
GO:0000993	RNA polymerase II complex binding	23/5085	36/18639	0.638888888888889	2.34183874139626	4.74225996947103e-06	6.35175426213998e-05
GO:0044183	protein folding chaperone	39/5085	75/18639	0.52	1.90605309734513	4.85541681230195e-06	6.43828269311239e-05
GO:0004679	AMP-activated protein kinase activity	100/5085	248/18639	0.403225806451613	1.47801884099343	5.27259799606395e-06	6.91156526073402e-05
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	33/5085	60/18639	0.55	2.01601769911504	5.31658866210309e-06	6.91156526073402e-05
GO:0051020	GTPase binding	122/5085	315/18639	0.387301587301587	1.41964882708246	5.6598513637265e-06	7.28637175563236e-05
GO:0036121	double-stranded DNA helicase activity	28/5085	48/18639	0.583333333333333	2.1382005899705	5.94590699770132e-06	7.58103142206919e-05
GO:0019783	ubiquitin-like protein peptidase activity	58/5085	127/18639	0.456692913385827	1.67400181172044	6.60020104639438e-06	8.28332186106923e-05
GO:0051059	NF-kappaB binding	21/5085	32/18639	0.65625	2.40547566371681	6.62166000960285e-06	8.28332186106923e-05
GO:0008234	cysteine-type peptidase activity	79/5085	187/18639	0.422459893048128	1.54852113009323	6.68464269163638e-06	8.28395907393443e-05
GO:0003727	single-stranded RNA binding	44/5085	89/18639	0.49438202247191	1.81215074077757	6.96396601984738e-06	8.55020272436817e-05
GO:0004527	exonuclease activity	42/5085	84/18639	0.5	1.83274336283186	7.78936980894117e-06	9.47587556573944e-05
GO:0008186	ATP-dependent activity, acting on RNA	40/5085	79/18639	0.506329113924051	1.85594264590568	8.61517626424002e-06	0.000103852033876202
GO:0051537	2 iron, 2 sulfur cluster binding	19/5085	28/18639	0.678571428571429	2.48729456384324	8.83365033075674e-06	0.000105526309356608
GO:0060590	ATPase regulator activity	28/5085	49/18639	0.571428571428571	2.09456384323641	1.02689423331054e-05	0.000121576942265159
GO:0017069	snRNA binding	30/5085	54/18639	0.555555555555556	2.03638151425762	1.07986086112629e-05	0.000126716416093227
GO:0003724	RNA helicase activity	39/5085	77/18639	0.506493506493506	1.85654522468682	1.10080101084249e-05	0.000128040538629574
GO:0061631	ubiquitin conjugating enzyme activity	22/5085	35/18639	0.628571428571429	2.30402022756005	1.12485364288717e-05	0.000129700515692903
GO:0061733	protein-lysine-acetyltransferase activity	27/5085	47/18639	0.574468085106383	2.1057051402749	1.2897602942782e-05	0.00014743294398387
GO:0031267	small GTPase binding	110/5085	283/18639	0.3886925795053	1.42474749054067	1.32542545886427e-05	0.00015021488533795
GO:0042162	telomeric DNA binding	23/5085	38/18639	0.605263157894737	2.21858407079646	1.74708761479935e-05	0.000196325269256266
GO:0140101	catalytic activity, acting on a tRNA	61/5085	139/18639	0.438848920863309	1.60859489399631	1.80574489375166e-05	0.000201211573875185
GO:0032404	mismatch repair complex binding	10/5085	11/18639	0.909090909090909	3.33226065969429	1.87799306622705e-05	0.000205803207092319
GO:0070990	snRNP binding	10/5085	11/18639	0.909090909090909	3.33226065969429	1.87799306622705e-05	0.000205803207092319
GO:0019207	kinase regulator activity	110/5085	287/18639	0.383275261324042	1.40489038265857	2.70171686252417e-05	0.000293645619648119
GO:0030544	Hsp70 protein binding	28/5085	51/18639	0.549019607843137	2.01242408467812	2.83706651296843e-05	0.000305849609446841
GO:0004197	cysteine-type endopeptidase activity	42/5085	88/18639	0.477272727272727	1.7494368463395	3.29924972332342e-05	0.000352806865574747
GO:0001222	transcription corepressor binding	27/5085	49/18639	0.551020408163265	2.01975799169225	3.60308157155703e-05	0.000382214893110769
GO:0140767	enzyme-substrate adaptor activity	60/5085	139/18639	0.431654676258993	1.58222448589801	3.83141526508393e-05	0.000403210844563595
GO:0005096	GTPase activator activity	104/5085	271/18639	0.383763837638376	1.40668125265323	4.15191441445804e-05	0.0004334990955568
GO:0004402	histone acetyltransferase activity	24/5085	42/18639	0.571428571428571	2.09456384323641	4.38494105199316e-05	0.000454252487104917
GO:0046966	nuclear thyroid hormone receptor binding	18/5085	28/18639	0.642857142857143	2.35638432364096	4.63657732571144e-05	0.000476597018131269
GO:0010485	histone H4 acetyltransferase activity	21/5085	35/18639	0.6	2.19929203539823	4.8809765264281e-05	0.000497859605695666
GO:0032182	ubiquitin-like protein binding	53/5085	120/18639	0.441666666666667	1.61892330383481	5.03428119151456e-05	0.000509576859538038
GO:0004532	RNA exonuclease activity	23/5085	40/18639	0.575	2.10765486725664	5.52011137658985e-05	0.000554520279193798
GO:0004715	non-membrane spanning protein tyrosine kinase activity	25/5085	45/18639	0.555555555555556	2.03638151425762	5.80551905908732e-05	0.000578805885139082
GO:0019887	protein kinase regulator activity	98/5085	255/18639	0.384313725490196	1.40869685927468	6.38122660691816e-05	0.000631455707520409
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	22/5085	38/18639	0.578947368421053	2.12212389380531	6.93919520845372e-05	0.000681583173808121
GO:0034212	protein N-acetyltransferase activity	28/5085	53/18639	0.528301886792453	1.93648355318083	7.15088708378009e-05	0.000697211490668559
GO:0016407	acetyltransferase activity	44/5085	96/18639	0.458333333333333	1.68001474926254	7.37819782756437e-05	0.000714123380974479
GO:0061608	nuclear import signal receptor activity	14/5085	20/18639	0.7	2.5658407079646	8.4011593239331e-05	0.000807241830690963
GO:0043047	single-stranded telomeric DNA binding	10/5085	12/18639	0.833333333333333	3.05457227138643	8.48487139403656e-05	0.000809420105646941
GO:0000049	tRNA binding	38/5085	80/18639	0.475	1.74110619469027	8.7422063319707e-05	0.00082801182829951
GO:0030983	mismatched DNA binding	11/5085	14/18639	0.785714285714286	2.88002528445006	9.52716371061889e-05	0.000889649231005679
GO:0098847	sequence-specific single stranded DNA binding	11/5085	14/18639	0.785714285714286	2.88002528445006	9.52716371061889e-05	0.000889649231005679
GO:0008173	RNA methyltransferase activity	33/5085	67/18639	0.492537313432836	1.80538898428213	0.000103861063652364	0.000963075317503736
GO:0003714	transcription corepressor activity	80/5085	204/18639	0.392156862745098	1.43744577477009	0.000133261429777227	0.00122401180303573
GO:0017056	structural constituent of nuclear pore	16/5085	25/18639	0.64	2.34591150442478	0.000133847444525024	0.00122401180303573
GO:0008408	3'-5' exonuclease activity	29/5085	58/18639	0.5	1.83274336283186	0.000192090480837888	0.00174460258624
GO:0008080	N-acetyltransferase activity	33/5085	69/18639	0.478260869565217	1.75305886879569	0.000211833218309912	0.00191082209169349
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	25/5085	48/18639	0.520833333333333	1.90910766961652	0.000231704058542651	0.0020759431191051
GO:0004712	protein serine/threonine/tyrosine kinase activity	23/5085	43/18639	0.534883720930233	1.96060917884338	0.000244930985425188	0.00217972138707248
GO:0051787	misfolded protein binding	12/5085	17/18639	0.705882352941177	2.58740239458615	0.000246653216776729	0.00218041443630628
GO:0101005	deubiquitinase activity	49/5085	115/18639	0.426086956521739	1.56181608310889	0.000274366750508817	0.00240933980910392
GO:0140463	chromatin-protein adaptor activity	27/5085	54/18639	0.5	1.83274336283186	0.000316263473469435	0.00274961145738287
GO:0044390	ubiquitin-like protein conjugating enzyme binding	20/5085	36/18639	0.555555555555556	2.03638151425762	0.000317262860467254	0.00274961145738287
GO:0140034	methylation-dependent protein binding	35/5085	76/18639	0.460526315789474	1.68805309734513	0.000346082690511216	0.00297990680271346
GO:0016922	nuclear receptor binding	56/5085	137/18639	0.408759124087591	1.49830114333699	0.000382591972690902	0.00327301261798798
GO:0035064	methylated histone binding	34/5085	74/18639	0.459459459459459	1.68414254962928	0.000440723295717263	0.00374614801359674
GO:0000339	RNA cap binding	13/5085	20/18639	0.65	2.38256637168142	0.000467988247027113	0.00395256315642007
GO:0030515	snoRNA binding	18/5085	32/18639	0.5625	2.06183628318584	0.000514367998762106	0.00431678459720603
GO:0000400	four-way junction DNA binding	12/5085	18/18639	0.666666666666667	2.44365781710914	0.000555906260472254	0.00463604843639125
GO:0140296	general transcription initiation factor binding	26/5085	53/18639	0.490566037735849	1.7981632993822	0.000591944495185796	0.00490574000385228
GO:0005525	GTP binding	132/5085	378/18639	0.349206349206349	1.28001123753336	0.000602084211236505	0.0049587805223578
GO:0031624	ubiquitin conjugating enzyme binding	17/5085	30/18639	0.566666666666667	2.07710914454277	0.000654361171722124	0.00523250429108457
GO:0043995	histone H4K5 acetyltransferase activity	17/5085	30/18639	0.566666666666667	2.07710914454277	0.000654361171722124	0.00523250429108457
GO:0043996	histone H4K8 acetyltransferase activity	17/5085	30/18639	0.566666666666667	2.07710914454277	0.000654361171722124	0.00523250429108457
GO:0043997	histone H4K12 acetyltransferase activity	17/5085	30/18639	0.566666666666667	2.07710914454277	0.000654361171722124	0.00523250429108457
GO:0000175	3'-5'-RNA exonuclease activity	19/5085	35/18639	0.542857142857143	1.98983565107459	0.000658995638469927	0.00523250429108457
GO:0140566	histone reader activity	19/5085	35/18639	0.542857142857143	1.98983565107459	0.000658995638469927	0.00523250429108457
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	50/5085	122/18639	0.409836065573771	1.5022486580589	0.000711164739215215	0.00561312169166295
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	52/5085	128/18639	0.40625	1.48910398230088	0.000718719401921748	0.00563918299969372
GO:0043539	protein serine/threonine kinase activator activity	33/5085	73/18639	0.452054794520548	1.65700084858771	0.000758856186858594	0.0058578532520302
GO:0005049	nuclear export signal receptor activity	9/5085	12/18639	0.75	2.74911504424779	0.000790415420784138	0.0058578532520302
GO:0005095	GTPase inhibitor activity	9/5085	12/18639	0.75	2.74911504424779	0.000790415420784138	0.0058578532520302
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	9/5085	12/18639	0.75	2.74911504424779	0.000790415420784138	0.0058578532520302
GO:1990817	poly(A) RNA polymerase activity	9/5085	12/18639	0.75	2.74911504424779	0.000790415420784138	0.0058578532520302
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	8/5085	10/18639	0.8	2.93238938053097	0.000790766012151889	0.0058578532520302
GO:0016783	sulfurtransferase activity	8/5085	10/18639	0.8	2.93238938053097	0.000790766012151889	0.0058578532520302
GO:0032356	oxidized DNA binding	8/5085	10/18639	0.8	2.93238938053097	0.000790766012151889	0.0058578532520302
GO:0098505	G-rich strand telomeric DNA binding	8/5085	10/18639	0.8	2.93238938053097	0.000790766012151889	0.0058578532520302
GO:1905394	retromer complex binding	8/5085	10/18639	0.8	2.93238938053097	0.000790766012151889	0.0058578532520302
GO:0019902	phosphatase binding	72/5085	190/18639	0.378947368421053	1.38902654867257	0.000883695583320309	0.00650989079712628
GO:0016763	pentosyltransferase activity	24/5085	49/18639	0.489795918367347	1.79534043705978	0.000977756110578639	0.00716300885429434
GO:0016791	phosphatase activity	98/5085	273/18639	0.358974358974359	1.31581574767415	0.00105097369330654	0.00765709405123337
GO:0140457	protein demethylase activity	17/5085	31/18639	0.548387096774194	2.01010562375107	0.00108263164831374	0.0078446424353225
GO:0004540	RNA nuclease activity	49/5085	121/18639	0.40495867768595	1.48437065750018	0.0010930579662668	0.00787714599603137
GO:0016853	isomerase activity	68/5085	180/18639	0.377777777777778	1.38473942969518	0.00132542147405226	0.00950004797077456
GO:0010484	histone H3 acetyltransferase activity	16/5085	29/18639	0.551724137931034	2.02233750381446	0.00138807323974677	0.00989561890271083
GO:0019903	protein phosphatase binding	56/5085	144/18639	0.388888888888889	1.42546705998033	0.00157532971034994	0.0111705197642995
GO:0051539	4 iron, 4 sulfur cluster binding	22/5085	45/18639	0.488888888888889	1.79201573254671	0.00161940745329173	0.0113900925488948
GO:0004721	phosphoprotein phosphatase activity	66/5085	175/18639	0.377142857142857	1.38241213653603	0.00162348672752376	0.0113900925488948
GO:0004843	cysteine-type deubiquitinase activity	44/5085	108/18639	0.407407407407407	1.49334644378892	0.00165512823426816	0.0113900925488948
GO:0000774	adenyl-nucleotide exchange factor activity	10/5085	15/18639	0.666666666666667	2.44365781710914	0.00165783398336101	0.0113900925488948
GO:0042809	nuclear vitamin D receptor binding	10/5085	15/18639	0.666666666666667	2.44365781710914	0.00165783398336101	0.0113900925488948
GO:0050700	CARD domain binding	10/5085	15/18639	0.666666666666667	2.44365781710914	0.00165783398336101	0.0113900925488948
GO:0004407	histone deacetylase activity	13/5085	22/18639	0.590909090909091	2.16596942880129	0.0016927024814755	0.0113935202560229
GO:0033558	protein lysine deacetylase activity	13/5085	22/18639	0.590909090909091	2.16596942880129	0.0016927024814755	0.0113935202560229
GO:0034062	5'-3' RNA polymerase activity	13/5085	22/18639	0.590909090909091	2.16596942880129	0.0016927024814755	0.0113935202560229
GO:0097747	RNA polymerase activity	13/5085	22/18639	0.590909090909091	2.16596942880129	0.0016927024814755	0.0113935202560229
GO:0022884	macromolecule transmembrane transporter activity	17/5085	32/18639	0.53125	1.94728982300885	0.00172666378447225	0.0115634150414657
GO:0001671	ATPase activator activity	15/5085	27/18639	0.555555555555556	2.03638151425762	0.00177990844648314	0.0118600934675208
GO:0009982	pseudouridine synthase activity	9/5085	13/18639	0.692307692307692	2.53764465622873	0.00194532777918806	0.0126446305647224
GO:0046975	histone H3K36 methyltransferase activity	9/5085	13/18639	0.692307692307692	2.53764465622873	0.00194532777918806	0.0126446305647224
GO:0051011	microtubule minus-end binding	9/5085	13/18639	0.692307692307692	2.53764465622873	0.00194532777918806	0.0126446305647224
GO:0140666	annealing activity	9/5085	13/18639	0.692307692307692	2.53764465622873	0.00194532777918806	0.0126446305647224
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	9/5085	13/18639	0.692307692307692	2.53764465622873	0.00194532777918806	0.0126446305647224
GO:0019843	rRNA binding	29/5085	65/18639	0.446153846153846	1.63537100068074	0.0019806096295271	0.0128111627744046
GO:0043015	gamma-tubulin binding	18/5085	35/18639	0.514285714285714	1.88510745891277	0.00206131439579556	0.013195270408131
GO:0140223	general transcription initiation factor activity	30/5085	68/18639	0.441176470588235	1.61712649661635	0.00206984633853035	0.013195270408131
GO:1990841	promoter-specific chromatin binding	30/5085	68/18639	0.441176470588235	1.61712649661635	0.00206984633853035	0.013195270408131
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	12/5085	20/18639	0.6	2.19929203539823	0.00213422401667082	0.01347610021955
GO:0043024	ribosomal small subunit binding	12/5085	20/18639	0.6	2.19929203539823	0.00213422401667082	0.01347610021955
GO:0032452	histone demethylase activity	16/5085	30/18639	0.533333333333333	1.95492625368732	0.00222660131748922	0.0139267610707108
GO:0070566	adenylyltransferase activity	16/5085	30/18639	0.533333333333333	1.95492625368732	0.00222660131748922	0.0139267610707108
GO:0008139	nuclear localization sequence binding	14/5085	25/18639	0.56	2.05267256637168	0.0022824010564138	0.0142087502385197
GO:0003924	GTPase activity	114/5085	331/18639	0.344410876132931	1.26243349463947	0.00232314558692969	0.0143948179825643
GO:0008276	protein methyltransferase activity	39/5085	95/18639	0.410526315789474	1.50477876106195	0.00250535725919884	0.0154516452358031
GO:0008170	N-methyltransferase activity	40/5085	98/18639	0.408163265306122	1.49611703088315	0.00252008161832983	0.0154705010458581
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	11/5085	18/18639	0.611111111111111	2.24001966568338	0.00267921512492874	0.0163669894636288
GO:0140318	protein transporter activity	20/5085	41/18639	0.48780487804878	1.78804230520181	0.0026908021893447	0.0163669894636288
GO:0036408	histone H3K14 acetyltransferase activity	15/5085	28/18639	0.535714285714286	1.96365360303413	0.00287396119033521	0.0173221479017476
GO:0141052	histone H3 demethylase activity	15/5085	28/18639	0.535714285714286	1.96365360303413	0.00287396119033521	0.0173221479017476
GO:0043014	alpha-tubulin binding	21/5085	44/18639	0.477272727272727	1.7494368463395	0.00297694142301762	0.0178616485381057
GO:0005085	guanyl-nucleotide exchange factor activity	82/5085	230/18639	0.356521739130435	1.30682570219315	0.0031673699921	0.0189186153582189
GO:0045296	cadherin binding	114/5085	334/18639	0.341317365269461	1.25109427163372	0.00325005788835215	0.019325456322668
GO:0004536	DNA nuclease activity	28/5085	64/18639	0.4375	1.60365044247788	0.00332564725128551	0.0195229498962717
GO:0000062	fatty-acyl-CoA binding	10/5085	16/18639	0.625	2.29092920353982	0.00334216412251408	0.0195229498962717
GO:0004708	MAP kinase kinase activity	10/5085	16/18639	0.625	2.29092920353982	0.00334216412251408	0.0195229498962717
GO:0043023	ribosomal large subunit binding	10/5085	16/18639	0.625	2.29092920353982	0.00334216412251408	0.0195229498962717
GO:0051879	Hsp90 protein binding	20/5085	42/18639	0.476190476190476	1.74546986936367	0.00383511481094548	0.0223042203478671
GO:0016410	N-acyltransferase activity	38/5085	94/18639	0.404255319148936	1.48179250611937	0.00387168416419388	0.0224185729332799
GO:0160215	deacylase activity	28/5085	65/18639	0.430769230769231	1.57897889720899	0.00434351355964328	0.0250412999134217
GO:0030145	manganese ion binding	29/5085	68/18639	0.426470588235294	1.56322228006247	0.00445382733756442	0.0255661257558893
GO:0019001	guanyl nucleotide binding	133/5085	400/18639	0.3325	1.21877433628319	0.00454701797060267	0.0258770207254041
GO:0032561	guanyl ribonucleotide binding	133/5085	400/18639	0.3325	1.21877433628319	0.00454701797060267	0.0258770207254041
GO:0120227	acyl-CoA binding	11/5085	19/18639	0.578947368421053	2.12212389380531	0.00480322240873943	0.0271024379318659
GO:0140036	ubiquitin-modified protein reader activity	11/5085	19/18639	0.578947368421053	2.12212389380531	0.00480322240873943	0.0271024379318659
GO:0015036	disulfide oxidoreductase activity	19/5085	40/18639	0.475	1.74110619469027	0.00494496131331651	0.0274349518242752
GO:0000340	RNA 7-methylguanosine cap binding	8/5085	12/18639	0.666666666666667	2.44365781710914	0.00502767216689205	0.0274349518242752
GO:0000995	RNA polymerase III general transcription initiation factor activity	8/5085	12/18639	0.666666666666667	2.44365781710914	0.00502767216689205	0.0274349518242752
GO:0034452	dynactin binding	8/5085	12/18639	0.666666666666667	2.44365781710914	0.00502767216689205	0.0274349518242752
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	8/5085	12/18639	0.666666666666667	2.44365781710914	0.00502767216689205	0.0274349518242752
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	8/5085	12/18639	0.666666666666667	2.44365781710914	0.00502767216689205	0.0274349518242752
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	8/5085	12/18639	0.666666666666667	2.44365781710914	0.00502767216689205	0.0274349518242752
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	8/5085	12/18639	0.666666666666667	2.44365781710914	0.00502767216689205	0.0274349518242752
GO:0035591	signaling adaptor activity	49/5085	129/18639	0.37984496124031	1.39231666323661	0.0051190198497489	0.0278189357408485
GO:0008320	protein transmembrane transporter activity	14/5085	27/18639	0.518518518518518	1.90062274664045	0.00579539053454754	0.0313660728522859
GO:0140789	histone phosphatase activity	51/5085	136/18639	0.375	1.37455752212389	0.00584673983491528	0.0315153537442995
GO:0051219	phosphoprotein binding	37/5085	93/18639	0.397849462365591	1.45831192311352	0.00590085146284817	0.0316782552216059
GO:0008641	ubiquitin-like modifier activating enzyme activity	7/5085	10/18639	0.7	2.5658407079646	0.00597103793177082	0.0319257915222908
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	10/5085	17/18639	0.588235294117647	2.15616866215513	0.00614291646105039	0.0323234413783842
GO:0004659	prenyltransferase activity	10/5085	17/18639	0.588235294117647	2.15616866215513	0.00614291646105039	0.0323234413783842
GO:0032183	SUMO binding	10/5085	17/18639	0.588235294117647	2.15616866215513	0.00614291646105039	0.0323234413783842
GO:1901567	fatty acid derivative binding	10/5085	17/18639	0.588235294117647	2.15616866215513	0.00614291646105039	0.0323234413783842
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	12/5085	22/18639	0.545454545454545	1.99935639581657	0.00621997484007541	0.0323438691683921
GO:0070034	telomerase RNA binding	12/5085	22/18639	0.545454545454545	1.99935639581657	0.00621997484007541	0.0323438691683921
GO:0140517	protein-RNA adaptor activity	12/5085	22/18639	0.545454545454545	1.99935639581657	0.00621997484007541	0.0323438691683921
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	80/5085	229/18639	0.349344978165939	1.28051938014453	0.00638905050621187	0.0330932850438943
GO:0035925	mRNA 3'-UTR AU-rich region binding	15/5085	30/18639	0.5	1.83274336283186	0.00670536667158499	0.0345965611148704
GO:0000149	SNARE binding	41/5085	106/18639	0.386792452830189	1.41778260143597	0.0069162152381733	0.0354671505483076
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	26/5085	61/18639	0.426229508196721	1.56233860438126	0.00692759577074787	0.0354671505483076
GO:0004722	protein serine/threonine phosphatase activity	40/5085	103/18639	0.388349514563107	1.42348999054902	0.00700255157616877	0.0357130130384607
GO:0043130	ubiquitin binding	39/5085	100/18639	0.39	1.42953982300885	0.00708228746637559	0.0359812765533105
GO:0019205	nucleobase-containing compound kinase activity	20/5085	44/18639	0.454545454545455	1.66613032984714	0.00733783503529235	0.0371372872396857
GO:0017025	TBP-class protein binding	13/5085	25/18639	0.52	1.90605309734513	0.00753369104151916	0.0379835525515377
GO:0061578	K63-linked deubiquitinase activity	9/5085	15/18639	0.6	2.19929203539823	0.00783769302819684	0.0393665945279887
GO:0016505	peptidase activator activity involved in apoptotic process	11/5085	20/18639	0.55	2.01601769911504	0.00806533155460108	0.0402053745917332
GO:0052745	inositol phosphate phosphatase activity	11/5085	20/18639	0.55	2.01601769911504	0.00806533155460108	0.0402053745917332
GO:0055106	ubiquitin-protein transferase regulator activity	17/5085	36/18639	0.472222222222222	1.73092428711898	0.00824544975956721	0.0409493122890866
GO:0097718	disordered domain specific binding	14/5085	28/18639	0.5	1.83274336283186	0.00871681987875988	0.0431287431314761
GO:0019209	kinase activator activity	54/5085	148/18639	0.364864864864865	1.33740731882325	0.00877493921686728	0.0432549048385354
GO:0000217	DNA secondary structure binding	18/5085	39/18639	0.461538461538462	1.69176310415248	0.00887518139121404	0.0435870019435179
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	33/5085	83/18639	0.397590361445783	1.45736219213136	0.00907763862376357	0.0444167852956107
GO:0031491	nucleosome binding	30/5085	74/18639	0.405405405405405	1.48600813202583	0.00914211112947525	0.0445677917561918
GO:0016829	lyase activity	70/5085	200/18639	0.35	1.2829203539823	0.00972826579269223	0.046974952412231
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	12/5085	23/18639	0.521739130434783	1.91242785686803	0.00981301796243438	0.046974952412231
GO:0008171	O-methyltransferase activity	12/5085	23/18639	0.521739130434783	1.91242785686803	0.00981301796243438	0.046974952412231
GO:0044013	histone H2B acetyltransferase activity	12/5085	23/18639	0.521739130434783	1.91242785686803	0.00981301796243438	0.046974952412231
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	12/5085	23/18639	0.521739130434783	1.91242785686803	0.00981301796243438	0.046974952412231
GO:0019104	DNA N-glycosylase activity	8/5085	13/18639	0.615384615384615	2.25568413886998	0.00995942318721844	0.0475042990872361
GO:0140693	molecular condensate scaffold activity	21/5085	48/18639	0.4375	1.60365044247788	0.0102603535882663	0.0487642611399322
GO:0008409	5'-3' exonuclease activity	10/5085	18/18639	0.555555555555556	2.03638151425762	0.0104725431312025	0.0495949721141945
GO:0008175	tRNA methyltransferase activity	16/5085	34/18639	0.470588235294118	1.7249349297241	0.0106652790531316	0.049621614120886
GO:0015035	protein-disulfide reductase activity	16/5085	34/18639	0.470588235294118	1.7249349297241	0.0106652790531316	0.049621614120886
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	16/5085	34/18639	0.470588235294118	1.7249349297241	0.0106652790531316	0.049621614120886
GO:0030332	cyclin binding	16/5085	34/18639	0.470588235294118	1.7249349297241	0.0106652790531316	0.049621614120886
GO:0052866	phosphatidylinositol phosphate phosphatase activity	16/5085	34/18639	0.470588235294118	1.7249349297241	0.0106652790531316	0.049621614120886
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	23/5085	54/18639	0.425925925925926	1.56122582759751	0.0108291039073245	0.0502076635703227
GO:0019210	kinase inhibitor activity	35/5085	90/18639	0.388888888888889	1.42546705998033	0.010875562263108	0.0502473712922689
GO:0004860	protein kinase inhibitor activity	33/5085	84/18639	0.392857142857143	1.44001264222503	0.0111103840253405	0.0511540597833388
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	25/5085	60/18639	0.416666666666667	1.52728613569322	0.0111741740050721	0.0512697395526836
GO:0001221	transcription coregulator binding	43/5085	115/18639	0.373913043478261	1.37057329742209	0.0113295469563583	0.0513840539630759
GO:0019003	GDP binding	30/5085	75/18639	0.4	1.46619469026549	0.0113350876044584	0.0513840539630759
GO:0004529	DNA exonuclease activity	13/5085	26/18639	0.5	1.83274336283186	0.0113540933719316	0.0513840539630759
GO:0050681	nuclear androgen receptor binding	13/5085	26/18639	0.5	1.83274336283186	0.0113540933719316	0.0513840539630759
GO:0032451	demethylase activity	18/5085	40/18639	0.45	1.64946902654867	0.012090816000403	0.0539812189108899
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	18/5085	40/18639	0.45	1.64946902654867	0.012090816000403	0.0539812189108899
GO:0061791	GTPase motor activity	18/5085	40/18639	0.45	1.64946902654867	0.012090816000403	0.0539812189108899
GO:1990606	membrane scission GTPase motor activity	18/5085	40/18639	0.45	1.64946902654867	0.012090816000403	0.0539812189108899
GO:0034511	U3 snoRNA binding	7/5085	11/18639	0.636363636363636	2.332582461786	0.0125653942241012	0.0558781981712615
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	14/5085	29/18639	0.482758620689655	1.76954531583766	0.0126842667040345	0.0558781981712615
GO:0097472	cyclin-dependent protein kinase activity	14/5085	29/18639	0.482758620689655	1.76954531583766	0.0126842667040345	0.0558781981712615
GO:0106222	lncRNA binding	14/5085	29/18639	0.482758620689655	1.76954531583766	0.0126842667040345	0.0558781981712615
GO:0051010	microtubule plus-end binding	11/5085	21/18639	0.523809523809524	1.92001685630004	0.0128115873557393	0.0562522014361267
GO:0009055	electron transfer activity	43/5085	116/18639	0.370689655172414	1.35875801037534	0.013346045893238	0.0584054681664475
GO:0017070	U6 snRNA binding	9/5085	16/18639	0.5625	2.06183628318584	0.0136176587640747	0.0593980773722468
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	32/5085	82/18639	0.390243902439024	1.43043384416145	0.0136644421384472	0.0594067222150198
GO:0070717	poly-purine tract binding	15/5085	32/18639	0.46875	1.71819690265487	0.0138130913252217	0.0598567290759607
GO:0001091	RNA polymerase II general transcription initiation factor binding	12/5085	24/18639	0.5	1.83274336283186	0.0148230156756044	0.0634042541479079
GO:0043998	histone H2A acetyltransferase activity	12/5085	24/18639	0.5	1.83274336283186	0.0148230156756044	0.0634042541479079
GO:0048027	mRNA 5'-UTR binding	12/5085	24/18639	0.5	1.83274336283186	0.0148230156756044	0.0634042541479079
GO:0140612	DNA damage sensor activity	12/5085	24/18639	0.5	1.83274336283186	0.0148230156756044	0.0634042541479079
GO:0030295	protein kinase activator activity	50/5085	139/18639	0.359712230215827	1.31852040491501	0.0151382909234246	0.0645446101751156
GO:0016877	ligase activity, forming carbon-sulfur bonds	18/5085	41/18639	0.439024390243902	1.60923807468163	0.0161596619207348	0.0686785631631229
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	13/5085	27/18639	0.481481481481481	1.76486397902327	0.0165157460066453	0.0699676651910917
GO:0016790	thiolester hydrolase activity	19/5085	44/18639	0.431818181818182	1.58282381335479	0.0166553068985496	0.0703341941002446
GO:1990380	K48-linked deubiquitinase activity	10/5085	19/18639	0.526315789473684	1.92920353982301	0.0167717883783836	0.0705685163193056
GO:0004519	endonuclease activity	46/5085	127/18639	0.362204724409449	1.32765660929552	0.0168704522422473	0.0705685163193056
GO:0042826	histone deacetylase binding	46/5085	127/18639	0.362204724409449	1.32765660929552	0.0168704522422473	0.0705685163193056
GO:0140938	histone H3 methyltransferase activity	20/5085	47/18639	0.425531914893617	1.55978158538882	0.0170355293018143	0.0710349429377538
GO:0032813	tumor necrosis factor receptor superfamily binding	21/5085	50/18639	0.42	1.53950442477876	0.0173148437798188	0.0719733004766134
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	27/5085	68/18639	0.397058823529412	1.45541384695471	0.0175013583129872	0.0720907898737808
GO:0016251	RNA polymerase II general transcription initiation factor activity	22/5085	53/18639	0.415094339622642	1.52152279178494	0.0175062099090177	0.0720907898737808
GO:0016860	intramolecular oxidoreductase activity	22/5085	53/18639	0.415094339622642	1.52152279178494	0.0175062099090177	0.0720907898737808
GO:0008474	palmitoyl-(protein) hydrolase activity	8/5085	14/18639	0.571428571428571	2.09456384323641	0.0177322839684492	0.0723477185912728
GO:0032454	histone H3K9 demethylase activity	8/5085	14/18639	0.571428571428571	2.09456384323641	0.0177322839684492	0.0723477185912728
GO:0098599	palmitoyl hydrolase activity	8/5085	14/18639	0.571428571428571	2.09456384323641	0.0177322839684492	0.0723477185912728
GO:0008649	rRNA methyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0032931	histone H3K56 acetyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0043992	histone H3K9 acetyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0043993	histone H3K18 acetyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0043994	histone H3K23 acetyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0043999	histone H2AK5 acetyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0044012	histone H2AK9 acetyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0044014	histone H2BK5 acetyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0044015	histone H2BK12 acetyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0044016	histone H3K4 acetyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0044017	histone H3K27 acetyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0044018	histone H3K36 acetyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0046972	histone H4K16 acetyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0140035	ubiquitin-like protein reader activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0140908	histone H3K122 acetyltransferase activity	11/5085	22/18639	0.5	1.83274336283186	0.0194031998714031	0.0756724794984722
GO:0033192	calmodulin-dependent protein phosphatase activity	31/5085	81/18639	0.382716049382716	1.40284059871081	0.0202367635315565	0.0771090472495517
GO:0140791	histone H2AXS140 phosphatase activity	31/5085	81/18639	0.382716049382716	1.40284059871081	0.0202367635315565	0.0771090472495517
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	31/5085	81/18639	0.382716049382716	1.40284059871081	0.0202367635315565	0.0771090472495517
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	31/5085	81/18639	0.382716049382716	1.40284059871081	0.0202367635315565	0.0771090472495517
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	31/5085	81/18639	0.382716049382716	1.40284059871081	0.0202367635315565	0.0771090472495517
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	31/5085	81/18639	0.382716049382716	1.40284059871081	0.0202367635315565	0.0771090472495517
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	31/5085	81/18639	0.382716049382716	1.40284059871081	0.0202367635315565	0.0771090472495517
GO:1990439	MAP kinase serine/threonine phosphatase activity	31/5085	81/18639	0.382716049382716	1.40284059871081	0.0202367635315565	0.0771090472495517
GO:0016874	ligase activity	58/5085	167/18639	0.347305389221557	1.27304329394309	0.020356528124521	0.0773431412410169
GO:0016776	phosphotransferase activity, phosphate group as acceptor	17/5085	39/18639	0.435897435897436	1.5977762650329	0.0206768395859485	0.078335683688479
GO:0048487	beta-tubulin binding	18/5085	42/18639	0.428571428571429	1.57092288242731	0.0212168314194003	0.080152474251068
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	12/5085	25/18639	0.48	1.75943362831858	0.0215516230301446	0.0811722882334359
GO:0140303	intramembrane lipid transporter activity	19/5085	45/18639	0.422222222222222	1.54764995083579	0.0216092139867292	0.0811722882334359
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	9/5085	17/18639	0.529411764705882	1.94055179593961	0.022026743854977	0.082294916299798
GO:0016830	carbon-carbon lyase activity	21/5085	51/18639	0.411764705882353	1.50931806350859	0.0220321985568841	0.082294916299798
GO:0003995	acyl-CoA dehydrogenase activity	7/5085	12/18639	0.583333333333333	2.1382005899705	0.0231182051041941	0.0844483194715189
GO:0004126	cytidine deaminase activity	7/5085	12/18639	0.583333333333333	2.1382005899705	0.0231182051041941	0.0844483194715189
GO:0004300	enoyl-CoA hydratase activity	7/5085	12/18639	0.583333333333333	2.1382005899705	0.0231182051041941	0.0844483194715189
GO:0016273	arginine N-methyltransferase activity	7/5085	12/18639	0.583333333333333	2.1382005899705	0.0231182051041941	0.0844483194715189
GO:0016274	protein-arginine N-methyltransferase activity	7/5085	12/18639	0.583333333333333	2.1382005899705	0.0231182051041941	0.0844483194715189
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	7/5085	12/18639	0.583333333333333	2.1382005899705	0.0231182051041941	0.0844483194715189
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	7/5085	12/18639	0.583333333333333	2.1382005899705	0.0231182051041941	0.0844483194715189
GO:1990247	N6-methyladenosine-containing RNA reader activity	7/5085	12/18639	0.583333333333333	2.1382005899705	0.0231182051041941	0.0844483194715189
GO:0016866	intramolecular transferase activity	13/5085	28/18639	0.464285714285714	1.70183312262958	0.0232748153174794	0.0845545345506239
GO:0019789	SUMO transferase activity	13/5085	28/18639	0.464285714285714	1.70183312262958	0.0232748153174794	0.0845545345506239
GO:0033549	MAP kinase phosphatase activity	31/5085	82/18639	0.378048780487805	1.38573278653141	0.0242317039861917	0.0877902718188255
GO:0005164	tumor necrosis factor receptor binding	14/5085	31/18639	0.451612903225806	1.65538110191265	0.0246321516411188	0.0889979102891651
GO:0030742	GTP-dependent protein binding	10/5085	20/18639	0.5	1.83274336283186	0.025478245202166	0.0913085219947895
GO:0140664	ATP-dependent DNA damage sensor activity	10/5085	20/18639	0.5	1.83274336283186	0.025478245202166	0.0913085219947895
GO:0140939	histone H4 methyltransferase activity	10/5085	20/18639	0.5	1.83274336283186	0.025478245202166	0.0913085219947895
GO:0042054	histone methyltransferase activity	26/5085	67/18639	0.388059701492537	1.42242768458592	0.0264402794471515	0.0943225405025099
GO:0019213	deacetylase activity	16/5085	37/18639	0.432432432432432	1.58507534082755	0.0264615271997992	0.0943225405025099
GO:0048156	tau protein binding	18/5085	43/18639	0.418604651162791	1.5343897921383	0.0273980157809894	0.0973988443045359
GO:0003887	DNA-directed DNA polymerase activity	11/5085	23/18639	0.478260869565217	1.75305886879569	0.0281941999546245	0.0996946910395523
GO:0140102	catalytic activity, acting on a rRNA	11/5085	23/18639	0.478260869565217	1.75305886879569	0.0281941999546245	0.0996946910395523
GO:0031386	protein tag activity	8/5085	15/18639	0.533333333333333	1.95492625368732	0.0290403879001662	0.101069696471445
GO:0055105	ubiquitin-protein transferase inhibitor activity	8/5085	15/18639	0.533333333333333	1.95492625368732	0.0290403879001662	0.101069696471445
GO:0140776	protein-containing complex destabilizing activity	8/5085	15/18639	0.533333333333333	1.95492625368732	0.0290403879001662	0.101069696471445
GO:0141047	molecular tag activity	8/5085	15/18639	0.533333333333333	1.95492625368732	0.0290403879001662	0.101069696471445
GO:0141050	histone H3K deacetylase activity	8/5085	15/18639	0.533333333333333	1.95492625368732	0.0290403879001662	0.101069696471445
GO:0141051	histone H4K deacetylase activity	8/5085	15/18639	0.533333333333333	1.95492625368732	0.0290403879001662	0.101069696471445
GO:0035401	histone H3Y41 kinase activity	41/5085	115/18639	0.356521739130435	1.30682570219315	0.0299724857151052	0.1028012501821
GO:0140801	histone H2AXY142 kinase activity	41/5085	115/18639	0.356521739130435	1.30682570219315	0.0299724857151052	0.1028012501821
GO:0030957	Tat protein binding	6/5085	10/18639	0.6	2.19929203539823	0.0301581344802692	0.1028012501821
GO:0031996	thioesterase binding	6/5085	10/18639	0.6	2.19929203539823	0.0301581344802692	0.1028012501821
GO:0033204	ribonuclease P RNA binding	6/5085	10/18639	0.6	2.19929203539823	0.0301581344802692	0.1028012501821
GO:0043422	protein kinase B binding	6/5085	10/18639	0.6	2.19929203539823	0.0301581344802692	0.1028012501821
GO:0051864	histone H3K36 demethylase activity	6/5085	10/18639	0.6	2.19929203539823	0.0301581344802692	0.1028012501821
GO:0099122	RNA polymerase II C-terminal domain binding	6/5085	10/18639	0.6	2.19929203539823	0.0301581344802692	0.1028012501821
GO:0031369	translation initiation factor binding	14/5085	32/18639	0.4375	1.60365044247788	0.033046976331261	0.112359719526287
GO:0036002	pre-mRNA binding	23/5085	59/18639	0.389830508474576	1.4289185540723	0.033564168688865	0.113303645067238
GO:0045309	protein phosphorylated amino acid binding	23/5085	59/18639	0.389830508474576	1.4289185540723	0.033564168688865	0.113303645067238
GO:0000900	mRNA regulatory element binding translation repressor activity	9/5085	18/18639	0.5	1.83274336283186	0.0335809445787516	0.113303645067238
GO:0034061	DNA polymerase activity	15/5085	35/18639	0.428571428571429	1.57092288242731	0.0338697766740248	0.113988131649129
GO:0017018	myosin phosphatase activity	31/5085	84/18639	0.369047619047619	1.35273914875685	0.0340391624999028	0.11426817588575
GO:0001727	lipid kinase activity	17/5085	41/18639	0.414634146341463	1.51983595942154	0.0347179173146147	0.115768360099427
GO:0008137	NADH dehydrogenase (ubiquinone) activity	17/5085	41/18639	0.414634146341463	1.51983595942154	0.0347179173146147	0.115768360099427
GO:0001046	core promoter sequence-specific DNA binding	18/5085	44/18639	0.409090909090909	1.49951729686243	0.0348352757765245	0.115768360099427
GO:0003954	NADH dehydrogenase activity	18/5085	44/18639	0.409090909090909	1.49951729686243	0.0348352757765245	0.115768360099427
GO:0070182	DNA polymerase binding	10/5085	21/18639	0.476190476190476	1.74546986936367	0.0369933886989175	0.122633083536912
GO:0004535	poly(A)-specific ribonuclease activity	7/5085	13/18639	0.538461538461538	1.97372362151123	0.0384701173406656	0.126265781172581
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	7/5085	13/18639	0.538461538461538	1.97372362151123	0.0384701173406656	0.126265781172581
GO:0043560	insulin receptor substrate binding	7/5085	13/18639	0.538461538461538	1.97372362151123	0.0384701173406656	0.126265781172581
GO:0097157	pre-mRNA intronic binding	7/5085	13/18639	0.538461538461538	1.97372362151123	0.0384701173406656	0.126265781172581
GO:0019208	phosphatase regulator activity	41/5085	117/18639	0.35042735042735	1.28448680130096	0.0394067807602371	0.128739866035088
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	45/5085	130/18639	0.346153846153846	1.26882232811436	0.0394180886955096	0.128739866035088
GO:0004713	protein tyrosine kinase activity	48/5085	140/18639	0.342857142857143	1.25673830594185	0.0403875800539649	0.131582140421517
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	23/5085	60/18639	0.383333333333333	1.40510324483776	0.0407526813061762	0.132446214245073
GO:0008266	poly(U) RNA binding	12/5085	27/18639	0.444444444444444	1.6291052114061	0.0413136561216156	0.133614409798201
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	12/5085	27/18639	0.444444444444444	1.6291052114061	0.0413136561216156	0.133614409798201
GO:0016504	peptidase activator activity	22/5085	57/18639	0.385964912280702	1.41474926253687	0.0414822633095131	0.133833287465728
GO:0003925	G protein activity	21/5085	54/18639	0.388888888888889	1.42546705998033	0.0421547388030049	0.135672775856273
GO:0008187	poly-pyrimidine tract binding	13/5085	30/18639	0.433333333333333	1.58837758112094	0.0425578604091494	0.136638554243419
GO:0019239	deaminase activity	14/5085	33/18639	0.424242424242424	1.555054974524	0.043356899716587	0.138200117846621
GO:0071889	14-3-3 protein binding	14/5085	33/18639	0.424242424242424	1.555054974524	0.043356899716587	0.138200117846621
GO:0140311	protein sequestering activity	14/5085	33/18639	0.424242424242424	1.555054974524	0.043356899716587	0.138200117846621
GO:0004520	DNA endonuclease activity	17/5085	42/18639	0.404761904761905	1.48364938895912	0.0438986557233603	0.139524056762695
GO:0042578	phosphoric ester hydrolase activity	114/5085	363/18639	0.31404958677686	1.15114459153075	0.0439826966265508	0.139524056762695
GO:0030275	LRR domain binding	8/5085	16/18639	0.5	1.83274336283186	0.0444631170362579	0.139711121303502
GO:0097027	ubiquitin-protein transferase activator activity	8/5085	16/18639	0.5	1.83274336283186	0.0444631170362579	0.139711121303502
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	8/5085	16/18639	0.5	1.83274336283186	0.0444631170362579	0.139711121303502
GO:0140328	floppase activity	8/5085	16/18639	0.5	1.83274336283186	0.0444631170362579	0.139711121303502
GO:0016278	lysine N-methyltransferase activity	26/5085	70/18639	0.371428571428571	1.36146649810367	0.0456053884166401	0.14296157219968
GO:0017124	SH3 domain binding	40/5085	115/18639	0.347826086956522	1.27495190457868	0.0463844180583582	0.145060703644771
GO:0046527	glucosyltransferase activity	9/5085	19/18639	0.473684210526316	1.73628318584071	0.0487091851590828	0.151972657696338
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	6/5085	11/18639	0.545454545454545	1.99935639581657	0.0512694227876707	0.15773376941172
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	6/5085	11/18639	0.545454545454545	1.99935639581657	0.0512694227876707	0.15773376941172
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	6/5085	11/18639	0.545454545454545	1.99935639581657	0.0512694227876707	0.15773376941172
GO:0140031	phosphorylation-dependent protein binding	6/5085	11/18639	0.545454545454545	1.99935639581657	0.0512694227876707	0.15773376941172
GO:0140537	transcription regulator activator activity	6/5085	11/18639	0.545454545454545	1.99935639581657	0.0512694227876707	0.15773376941172
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	6/5085	11/18639	0.545454545454545	1.99935639581657	0.0512694227876707	0.15773376941172
GO:0050321	tau-protein kinase activity	10/5085	22/18639	0.454545454545455	1.66613032984714	0.051651879388513	0.158542574234186
GO:0004709	MAP kinase kinase kinase activity	11/5085	25/18639	0.44	1.61281415929204	0.0536170800476529	0.16343965090388
GO:0047617	fatty acyl-CoA hydrolase activity	11/5085	25/18639	0.44	1.61281415929204	0.0536170800476529	0.16343965090388
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	11/5085	25/18639	0.44	1.61281415929204	0.0536170800476529	0.16343965090388
GO:0051019	mitogen-activated protein kinase binding	12/5085	28/18639	0.428571428571429	1.57092288242731	0.0548427867247173	0.166792511919668
GO:0016831	carboxy-lyase activity	14/5085	34/18639	0.411764705882353	1.50931806350859	0.0557318831350349	0.169108643105392
GO:0019888	protein phosphatase regulator activity	37/5085	107/18639	0.345794392523364	1.26750475560334	0.0582488892627648	0.176342527768096
GO:0046030	inositol trisphosphate phosphatase activity	7/5085	14/18639	0.5	1.83274336283186	0.0592079507128821	0.178026627313564
GO:0070742	C2H2 zinc finger domain binding	7/5085	14/18639	0.5	1.83274336283186	0.0592079507128821	0.178026627313564
GO:1990825	sequence-specific mRNA binding	7/5085	14/18639	0.5	1.83274336283186	0.0592079507128821	0.178026627313564
GO:0031593	polyubiquitin modification-dependent protein binding	22/5085	59/18639	0.372881355932203	1.36679166041698	0.059944292020811	0.179832876062433
GO:0004549	tRNA-specific ribonuclease activity	8/5085	17/18639	0.470588235294118	1.7249349297241	0.0644065598640631	0.190368735386183
GO:0005092	GDP-dissociation inhibitor activity	8/5085	17/18639	0.470588235294118	1.7249349297241	0.0644065598640631	0.190368735386183
GO:0031489	myosin V binding	8/5085	17/18639	0.470588235294118	1.7249349297241	0.0644065598640631	0.190368735386183
GO:0032977	membrane insertase activity	8/5085	17/18639	0.470588235294118	1.7249349297241	0.0644065598640631	0.190368735386183
GO:0070402	NADPH binding	8/5085	17/18639	0.470588235294118	1.7249349297241	0.0644065598640631	0.190368735386183
GO:0015605	organophosphate ester transmembrane transporter activity	19/5085	50/18639	0.38	1.39288495575221	0.0644462903336879	0.190368735386183
GO:0004725	protein tyrosine phosphatase activity	34/5085	98/18639	0.346938775510204	1.27169947625068	0.064461208286875	0.190368735386183
GO:0016279	protein-lysine N-methyltransferase activity	25/5085	69/18639	0.36231884057971	1.3280749006028	0.0650013271473944	0.191537243994322
GO:0043531	ADP binding	15/5085	38/18639	0.394736842105263	1.44690265486726	0.0694598507809958	0.204221202074502
GO:0008143	poly(A) binding	11/5085	26/18639	0.423076923076923	1.55078284547311	0.0707218727419965	0.206534491071753
GO:0016289	acyl-CoA hydrolase activity	11/5085	26/18639	0.423076923076923	1.55078284547311	0.0707218727419965	0.206534491071753
GO:0052742	phosphatidylinositol kinase activity	11/5085	26/18639	0.423076923076923	1.55078284547311	0.0707218727419965	0.206534491071753
GO:0008378	galactosyltransferase activity	13/5085	32/18639	0.40625	1.48910398230088	0.0708696783089349	0.206534491071753
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	31/5085	89/18639	0.348314606741573	1.27674256736601	0.0713838647493954	0.207122548485117
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	31/5085	89/18639	0.348314606741573	1.27674256736601	0.0713838647493954	0.207122548485117
GO:0005048	signal sequence binding	19/5085	51/18639	0.372549019607843	1.36557348603158	0.0773259396640641	0.223873790381111
GO:0004526	ribonuclease P activity	6/5085	12/18639	0.5	1.83274336283186	0.0794206404711474	0.228442015758658
GO:0035197	siRNA binding	6/5085	12/18639	0.5	1.83274336283186	0.0794206404711474	0.228442015758658
GO:0141221	histone deacetylase activity, hydrolytic mechanism	6/5085	12/18639	0.5	1.83274336283186	0.0794206404711474	0.228442015758658
GO:0140793	histone H2AXY142 phosphatase activity	31/5085	90/18639	0.344444444444444	1.26255653883972	0.0813780398188978	0.233565542856836
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	7/5085	15/18639	0.466666666666667	1.7105604719764	0.0856045681740081	0.245165566735928
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	21/5085	58/18639	0.362068965517241	1.32715898687824	0.0862006271873372	0.246340585453468
GO:0140313	molecular sequestering activity	20/5085	55/18639	0.363636363636364	1.33290426387772	0.0889743541953387	0.25289702585526
GO:0003746	translation elongation factor activity	8/5085	18/18639	0.444444444444444	1.6291052114061	0.0890670520923124	0.25289702585526
GO:0004706	JUN kinase kinase kinase activity	8/5085	18/18639	0.444444444444444	1.6291052114061	0.0890670520923124	0.25289702585526
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9/5085	21/18639	0.428571428571429	1.57092288242731	0.0907585147152466	0.25547980663653
GO:0005123	death receptor binding	9/5085	21/18639	0.428571428571429	1.57092288242731	0.0907585147152466	0.25547980663653
GO:0009931	calcium-dependent protein serine/threonine kinase activity	9/5085	21/18639	0.428571428571429	1.57092288242731	0.0907585147152466	0.25547980663653
GO:0005548	phospholipid transporter activity	24/5085	68/18639	0.352941176470588	1.29370119729308	0.0907869299117926	0.25547980663653
GO:0004683	calcium/calmodulin-dependent protein kinase activity	11/5085	27/18639	0.407407407407407	1.49334644378892	0.0909400216685082	0.25547980663653
GO:0140033	acetylation-dependent protein binding	10/5085	24/18639	0.416666666666667	1.52728613569322	0.0912590833437136	0.255834132164406
GO:0022853	active monoatomic ion transmembrane transporter activity	39/5085	118/18639	0.330508474576271	1.21147442627869	0.0970762867427841	0.271567840128548
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	15/5085	40/18639	0.375	1.37455752212389	0.103478188422338	0.288867532311621
GO:0005131	growth hormone receptor binding	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:0008140	cAMP response element binding protein binding	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:0016427	tRNA (cytidine) methyltransferase activity	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:0045322	unmethylated CpG binding	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:0050815	phosphoserine residue binding	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:0051880	G-quadruplex DNA binding	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:0070513	death domain binding	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:0097177	mitochondrial ribosome binding	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:1990757	ubiquitin ligase activator activity	5/5085	10/18639	0.5	1.83274336283186	0.107575888393376	0.291113526550238
GO:0051018	protein kinase A binding	19/5085	53/18639	0.358490566037736	1.31404241108699	0.107915825625308	0.291438665538001
GO:0008327	methyl-CpG binding	12/5085	31/18639	0.387096774193548	1.4188980873537	0.111865474229012	0.301491095178191
GO:0005338	nucleotide-sugar transmembrane transporter activity	6/5085	13/18639	0.461538461538462	1.69176310415248	0.114521088868703	0.307398712226519
GO:0046974	histone H3K9 methyltransferase activity	6/5085	13/18639	0.461538461538462	1.69176310415248	0.114521088868703	0.307398712226519
GO:0004521	RNA endonuclease activity	25/5085	73/18639	0.342465753424658	1.25530367317251	0.115121671278831	0.308386537607534
GO:0051213	dioxygenase activity	31/5085	93/18639	0.333333333333333	1.22182890855457	0.116900191136177	0.310641847288449
GO:0005521	lamin binding	7/5085	16/18639	0.4375	1.60365044247788	0.117603474614481	0.310641847288449
GO:0008296	3'-5'-DNA exonuclease activity	7/5085	16/18639	0.4375	1.60365044247788	0.117603474614481	0.310641847288449
GO:0022858	alanine transmembrane transporter activity	7/5085	16/18639	0.4375	1.60365044247788	0.117603474614481	0.310641847288449
GO:0034450	ubiquitin-ubiquitin ligase activity	7/5085	16/18639	0.4375	1.60365044247788	0.117603474614481	0.310641847288449
GO:0070411	I-SMAD binding	7/5085	16/18639	0.4375	1.60365044247788	0.117603474614481	0.310641847288449
GO:0140327	flippase activity	7/5085	16/18639	0.4375	1.60365044247788	0.117603474614481	0.310641847288449
GO:0003756	protein disulfide isomerase activity	8/5085	19/18639	0.421052631578947	1.54336283185841	0.118418228043752	0.311552719019871
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	8/5085	19/18639	0.421052631578947	1.54336283185841	0.118418228043752	0.311552719019871
GO:0051287	NAD binding	19/5085	54/18639	0.351851851851852	1.28970829236316	0.125661441126033	0.329954595907167
GO:0031490	chromatin DNA binding	41/5085	128/18639	0.3203125	1.17410121681416	0.1338783645507	0.350835398012308
GO:0061980	regulatory RNA binding	20/5085	58/18639	0.344827586206897	1.26396093988404	0.139430991599005	0.36466567033586
GO:0035250	UDP-galactosyltransferase activity	11/5085	29/18639	0.379310344827586	1.39035703387244	0.140724547794635	0.367324311763162
GO:0034237	protein kinase A regulatory subunit binding	10/5085	26/18639	0.384615384615385	1.40980258679374	0.144873676873852	0.376671559872016
GO:0097602	cullin family protein binding	10/5085	26/18639	0.384615384615385	1.40980258679374	0.144873676873852	0.376671559872016
GO:0035198	miRNA binding	15/5085	42/18639	0.357142857142857	1.30910240202276	0.146066818535303	0.379030531072039
GO:0042171	lysophosphatidic acid acyltransferase activity	9/5085	23/18639	0.391304347826087	1.43432089265102	0.148776969093333	0.383064584500505
GO:0043274	phospholipase binding	9/5085	23/18639	0.391304347826087	1.43432089265102	0.148776969093333	0.383064584500505
GO:0070577	lysine-acetylated histone binding	9/5085	23/18639	0.391304347826087	1.43432089265102	0.148776969093333	0.383064584500505
GO:0071617	lysophospholipid acyltransferase activity	9/5085	23/18639	0.391304347826087	1.43432089265102	0.148776969093333	0.383064584500505
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	5/5085	11/18639	0.454545454545455	1.66613032984714	0.154497943064797	0.390341413707489
GO:0004143	ATP-dependent diacylglycerol kinase activity	5/5085	11/18639	0.454545454545455	1.66613032984714	0.154497943064797	0.390341413707489
GO:0015173	aromatic amino acid transmembrane transporter activity	5/5085	11/18639	0.454545454545455	1.66613032984714	0.154497943064797	0.390341413707489
GO:0019107	myristoyltransferase activity	5/5085	11/18639	0.454545454545455	1.66613032984714	0.154497943064797	0.390341413707489
GO:0019206	nucleoside kinase activity	5/5085	11/18639	0.454545454545455	1.66613032984714	0.154497943064797	0.390341413707489
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	5/5085	11/18639	0.454545454545455	1.66613032984714	0.154497943064797	0.390341413707489
GO:0042608	T cell receptor binding	5/5085	11/18639	0.454545454545455	1.66613032984714	0.154497943064797	0.390341413707489
GO:0180030	inositol phosphate kinase activity	5/5085	11/18639	0.454545454545455	1.66613032984714	0.154497943064797	0.390341413707489
GO:1990948	ubiquitin ligase inhibitor activity	5/5085	11/18639	0.454545454545455	1.66613032984714	0.154497943064797	0.390341413707489
GO:0004550	nucleoside diphosphate kinase activity	7/5085	17/18639	0.411764705882353	1.50931806350859	0.154841314939773	0.390341413707489
GO:0070403	NAD+ binding	7/5085	17/18639	0.411764705882353	1.50931806350859	0.154841314939773	0.390341413707489
GO:0008174	mRNA methyltransferase activity	6/5085	14/18639	0.428571428571429	1.57092288242731	0.156005942485569	0.391047031636794
GO:0034236	protein kinase A catalytic subunit binding	6/5085	14/18639	0.428571428571429	1.57092288242731	0.156005942485569	0.391047031636794
GO:0061665	SUMO ligase activity	6/5085	14/18639	0.428571428571429	1.57092288242731	0.156005942485569	0.391047031636794
GO:0016835	carbon-oxygen lyase activity	26/5085	79/18639	0.329113924050633	1.20636271983869	0.158690081149056	0.39702461812009
GO:0030291	protein serine/threonine kinase inhibitor activity	16/5085	46/18639	0.347826086956522	1.27495190457868	0.163591730422071	0.408083454740318
GO:0140416	transcription regulator inhibitor activity	12/5085	33/18639	0.363636363636364	1.33290426387772	0.163725790287971	0.408083454740318
GO:0051721	protein phosphatase 2A binding	11/5085	30/18639	0.366666666666667	1.34401179941003	0.170063480801223	0.423084757115238
GO:0004622	lysophospholipase activity	9/5085	24/18639	0.375	1.37455752212389	0.183287700543105	0.45343188604507
GO:0035035	histone acetyltransferase binding	9/5085	24/18639	0.375	1.37455752212389	0.183287700543105	0.45343188604507
GO:0070840	dynein complex binding	9/5085	24/18639	0.375	1.37455752212389	0.183287700543105	0.45343188604507
GO:0001784	phosphotyrosine residue binding	16/5085	47/18639	0.340425531914894	1.24782526831105	0.18836433529244	0.465123107258427
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	8/5085	21/18639	0.380952380952381	1.39637589549094	0.190041647222605	0.467523607081955
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	8/5085	21/18639	0.380952380952381	1.39637589549094	0.190041647222605	0.467523607081955
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	12/5085	34/18639	0.352941176470588	1.29370119729308	0.193470065805066	0.475076494921328
GO:0008525	phosphatidylcholine transporter activity	7/5085	18/18639	0.388888888888889	1.42546705998033	0.196697664024521	0.479450556059771
GO:0017128	phospholipid scramblase activity	7/5085	18/18639	0.388888888888889	1.42546705998033	0.196697664024521	0.479450556059771
GO:0070628	proteasome binding	7/5085	18/18639	0.388888888888889	1.42546705998033	0.196697664024521	0.479450556059771
GO:1990381	ubiquitin-specific protease binding	7/5085	18/18639	0.388888888888889	1.42546705998033	0.196697664024521	0.479450556059771
GO:0015078	proton transmembrane transporter activity	56/5085	185/18639	0.302702702702703	1.10955273857929	0.201001326585312	0.489041759728667
GO:0016878	acid-thiol ligase activity	11/5085	31/18639	0.354838709677419	1.30065658007422	0.20207238441594	0.489850058017435
GO:0070273	phosphatidylinositol-4-phosphate binding	11/5085	31/18639	0.354838709677419	1.30065658007422	0.20207238441594	0.489850058017435
GO:0048531	beta-1,3-galactosyltransferase activity	6/5085	15/18639	0.4	1.46619469026549	0.202940192026609	0.490956461346559
GO:0019905	syntaxin binding	20/5085	61/18639	0.327868852459016	1.20179892644712	0.203269304132173	0.490956461346559
GO:0035014	phosphatidylinositol 3-kinase regulator activity	5/5085	12/18639	0.416666666666667	1.52728613569322	0.208124587774547	0.500858808328584
GO:0097677	STAT family protein binding	5/5085	12/18639	0.416666666666667	1.52728613569322	0.208124587774547	0.500858808328584
GO:0016757	glycosyltransferase activity	79/5085	267/18639	0.295880149812734	1.08454476152597	0.215642103510319	0.518009835606309
GO:0001217	DNA-binding transcription repressor activity	82/5085	278/18639	0.294964028776978	1.08118673203031	0.220176818586608	0.527946584893025
GO:0005154	epidermal growth factor receptor binding	12/5085	35/18639	0.342857142857143	1.25673830594185	0.225450679324361	0.539616607913543
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	79/5085	268/18639	0.294776119402985	1.0804979527143	0.227095513617498	0.542574146048292
GO:0015399	primary active transmembrane transporter activity	50/5085	166/18639	0.301204819277108	1.10406226676618	0.2286696768732	0.545352502758747
GO:0016859	cis-trans isomerase activity	14/5085	42/18639	0.333333333333333	1.22182890855457	0.235504374309094	0.55963942712161
GO:0031492	nucleosomal DNA binding	14/5085	42/18639	0.333333333333333	1.22182890855457	0.235504374309094	0.55963942712161
GO:0043425	bHLH transcription factor binding	11/5085	32/18639	0.34375	1.2600110619469	0.23643923008183	0.560855848101086
GO:0008301	DNA binding, bending	7/5085	19/18639	0.368421052631579	1.35044247787611	0.242360668346637	0.571833178340997
GO:0046624	sphingolipid transporter activity	7/5085	19/18639	0.368421052631579	1.35044247787611	0.242360668346637	0.571833178340997
GO:0050145	nucleoside monophosphate kinase activity	7/5085	19/18639	0.368421052631579	1.35044247787611	0.242360668346637	0.571833178340997
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	13/5085	39/18639	0.333333333333333	1.22182890855457	0.246986613062641	0.581712697905971
GO:0016417	S-acyltransferase activity	10/5085	29/18639	0.344827586206897	1.26396093988404	0.248310270603031	0.583793295779467
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	6/5085	16/18639	0.375	1.37455752212389	0.254142222473887	0.595037877224514
GO:0015923	mannosidase activity	6/5085	16/18639	0.375	1.37455752212389	0.254142222473887	0.595037877224514
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	15/5085	46/18639	0.326086956521739	1.19526741054252	0.254439273292835	0.595037877224514
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	12/5085	36/18639	0.333333333333333	1.22182890855457	0.259371562946018	0.603380162221789
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	12/5085	36/18639	0.333333333333333	1.22182890855457	0.259371562946018	0.603380162221789
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	12/5085	36/18639	0.333333333333333	1.22182890855457	0.259371562946018	0.603380162221789
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	5/5085	13/18639	0.384615384615385	1.40980258679374	0.2666267745907	0.612317798798604
GO:0003964	RNA-directed DNA polymerase activity	5/5085	13/18639	0.384615384615385	1.40980258679374	0.2666267745907	0.612317798798604
GO:0005035	death receptor activity	5/5085	13/18639	0.384615384615385	1.40980258679374	0.2666267745907	0.612317798798604
GO:0019855	calcium channel inhibitor activity	5/5085	13/18639	0.384615384615385	1.40980258679374	0.2666267745907	0.612317798798604
GO:0035673	oligopeptide transmembrane transporter activity	5/5085	13/18639	0.384615384615385	1.40980258679374	0.2666267745907	0.612317798798604
GO:0140333	glycerophospholipid flippase activity	5/5085	13/18639	0.384615384615385	1.40980258679374	0.2666267745907	0.612317798798604
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	21/5085	67/18639	0.313432835820896	1.14888389908863	0.266637269684146	0.612317798798604
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	14/5085	43/18639	0.325581395348837	1.19341428277423	0.266907758450674	0.612317798798604
GO:0015932	nucleobase-containing compound transmembrane transporter activity	18/5085	57/18639	0.315789473684211	1.15752212389381	0.275895945738883	0.629481036813556
GO:0001094	TFIID-class transcription factor complex binding	4/5085	10/18639	0.4	1.46619469026549	0.279611109112507	0.629481036813556
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	4/5085	10/18639	0.4	1.46619469026549	0.279611109112507	0.629481036813556
GO:0004445	inositol-polyphosphate 5-phosphatase activity	4/5085	10/18639	0.4	1.46619469026549	0.279611109112507	0.629481036813556
GO:0004955	prostaglandin receptor activity	4/5085	10/18639	0.4	1.46619469026549	0.279611109112507	0.629481036813556
GO:0005522	profilin binding	4/5085	10/18639	0.4	1.46619469026549	0.279611109112507	0.629481036813556
GO:0005528	FK506 binding	4/5085	10/18639	0.4	1.46619469026549	0.279611109112507	0.629481036813556
GO:0015924	mannosyl-oligosaccharide mannosidase activity	4/5085	10/18639	0.4	1.46619469026549	0.279611109112507	0.629481036813556
GO:0016303	1-phosphatidylinositol-3-kinase activity	4/5085	10/18639	0.4	1.46619469026549	0.279611109112507	0.629481036813556
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	4/5085	10/18639	0.4	1.46619469026549	0.279611109112507	0.629481036813556
GO:0042975	peroxisome proliferator activated receptor binding	4/5085	10/18639	0.4	1.46619469026549	0.279611109112507	0.629481036813556
GO:0030331	nuclear estrogen receptor binding	13/5085	40/18639	0.325	1.19128318584071	0.280347017395952	0.630068042486497
GO:0015215	nucleotide transmembrane transporter activity	10/5085	30/18639	0.333333333333333	1.22182890855457	0.287433665503935	0.644901929709337
GO:0050661	NADP binding	17/5085	54/18639	0.314814814814815	1.15394952474599	0.288836462048263	0.646954643033778
GO:0016004	phospholipase activator activity	7/5085	20/18639	0.35	1.2829203539823	0.290898219722625	0.648287461096135
GO:0016408	C-acyltransferase activity	7/5085	20/18639	0.35	1.2829203539823	0.290898219722625	0.648287461096135
GO:0042288	MHC class I protein binding	7/5085	20/18639	0.35	1.2829203539823	0.290898219722625	0.648287461096135
GO:0050660	flavin adenine dinucleotide binding	26/5085	86/18639	0.302325581395349	1.10817040543322	0.305740828636496	0.679784134521963
GO:0046332	SMAD binding	24/5085	79/18639	0.30379746835443	1.11356558754341	0.306056657850386	0.679784134521963
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	6/5085	17/18639	0.352941176470588	1.29370119729308	0.30830635385613	0.682494532910231
GO:1990226	histone methyltransferase binding	6/5085	17/18639	0.352941176470588	1.29370119729308	0.30830635385613	0.682494532910231
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	13/5085	41/18639	0.317073170731707	1.16222749838118	0.315008342460795	0.696168436838357
GO:0016879	ligase activity, forming carbon-nitrogen bonds	15/5085	48/18639	0.3125	1.14546460176991	0.317495034391322	0.700496531785181
GO:0060229	lipase activator activity	8/5085	24/18639	0.333333333333333	1.22182890855457	0.321334025074855	0.707788899085145
GO:0072349	modified amino acid transmembrane transporter activity	10/5085	31/18639	0.32258064516129	1.18241507279475	0.328081894593456	0.717884129963775
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	5/5085	14/18639	0.357142857142857	1.30910240202276	0.328082792426884	0.717884129963775
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	5/5085	14/18639	0.357142857142857	1.30910240202276	0.328082792426884	0.717884129963775
GO:0071933	Arp2/3 complex binding	5/5085	14/18639	0.357142857142857	1.30910240202276	0.328082792426884	0.717884129963775
GO:0042887	amide transmembrane transporter activity	12/5085	38/18639	0.315789473684211	1.15752212389381	0.331666163706265	0.724529379035431
GO:0035091	phosphatidylinositol binding	81/5085	284/18639	0.285211267605634	1.04543811541817	0.33956760033674	0.739540762940709
GO:0009975	cyclase activity	7/5085	21/18639	0.333333333333333	1.22182890855457	0.341326505972635	0.739540762940709
GO:0035613	RNA stem-loop binding	7/5085	21/18639	0.333333333333333	1.22182890855457	0.341326505972635	0.739540762940709
GO:0072542	protein phosphatase activator activity	7/5085	21/18639	0.333333333333333	1.22182890855457	0.341326505972635	0.739540762940709
GO:1904047	S-adenosyl-L-methionine binding	7/5085	21/18639	0.333333333333333	1.22182890855457	0.341326505972635	0.739540762940709
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	4/5085	11/18639	0.363636363636364	1.33290426387772	0.351104346854056	0.749701069127984
GO:0004954	prostanoid receptor activity	4/5085	11/18639	0.363636363636364	1.33290426387772	0.351104346854056	0.749701069127984
GO:0005225	volume-sensitive anion channel activity	4/5085	11/18639	0.363636363636364	1.33290426387772	0.351104346854056	0.749701069127984
GO:0032794	GTPase activating protein binding	4/5085	11/18639	0.363636363636364	1.33290426387772	0.351104346854056	0.749701069127984
GO:0035252	UDP-xylosyltransferase activity	4/5085	11/18639	0.363636363636364	1.33290426387772	0.351104346854056	0.749701069127984
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	4/5085	11/18639	0.363636363636364	1.33290426387772	0.351104346854056	0.749701069127984
GO:0042285	xylosyltransferase activity	4/5085	11/18639	0.363636363636364	1.33290426387772	0.351104346854056	0.749701069127984
GO:0043522	leucine zipper domain binding	4/5085	11/18639	0.363636363636364	1.33290426387772	0.351104346854056	0.749701069127984
GO:0047676	arachidonate-CoA ligase activity	4/5085	11/18639	0.363636363636364	1.33290426387772	0.351104346854056	0.749701069127984
GO:0008308	voltage-gated monoatomic anion channel activity	6/5085	18/18639	0.333333333333333	1.22182890855457	0.364110698771935	0.773797457021649
GO:0050811	GABA receptor binding	6/5085	18/18639	0.333333333333333	1.22182890855457	0.364110698771935	0.773797457021649
GO:1901981	phosphatidylinositol phosphate binding	53/5085	185/18639	0.286486486486487	1.05011241329825	0.364139979774894	0.773797457021649
GO:0052689	carboxylic ester hydrolase activity	27/5085	92/18639	0.293478260869565	1.07574066948826	0.365344639613981	0.775115187405021
GO:0019211	phosphatase activator activity	8/5085	25/18639	0.32	1.17295575221239	0.368579191471615	0.779483266174419
GO:0042974	nuclear retinoic acid receptor binding	8/5085	25/18639	0.32	1.17295575221239	0.368579191471615	0.779483266174419
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	12/5085	39/18639	0.307692307692308	1.12784206943499	0.369301519547875	0.779767221210958
GO:0140299	molecular sensor activity	21/5085	71/18639	0.295774647887324	1.08415804561885	0.374608970206523	0.789716207462399
GO:0004129	cytochrome-c oxidase activity	5/5085	15/18639	0.333333333333333	1.22182890855457	0.390654092627021	0.814476928967656
GO:0004467	long-chain fatty acid-CoA ligase activity	5/5085	15/18639	0.333333333333333	1.22182890855457	0.390654092627021	0.814476928967656
GO:0004559	alpha-mannosidase activity	5/5085	15/18639	0.333333333333333	1.22182890855457	0.390654092627021	0.814476928967656
GO:0004953	icosanoid receptor activity	5/5085	15/18639	0.333333333333333	1.22182890855457	0.390654092627021	0.814476928967656
GO:0008252	nucleotidase activity	5/5085	15/18639	0.333333333333333	1.22182890855457	0.390654092627021	0.814476928967656
GO:0016846	carbon-sulfur lyase activity	5/5085	15/18639	0.333333333333333	1.22182890855457	0.390654092627021	0.814476928967656
GO:0017081	chloride channel regulator activity	5/5085	15/18639	0.333333333333333	1.22182890855457	0.390654092627021	0.814476928967656
GO:0061133	endopeptidase activator activity	7/5085	22/18639	0.318181818181818	1.166291230893	0.392670291242545	0.817395300137543
GO:0016836	hydro-lyase activity	18/5085	61/18639	0.295081967213115	1.08161903380241	0.39464157374496	0.820211170510684
GO:0120013	lipid transfer activity	19/5085	65/18639	0.292307692307692	1.07144996596324	0.407563443913138	0.845741982204728
GO:0005112	Notch binding	8/5085	26/18639	0.307692307692308	1.12784206943499	0.416299979402513	0.856121457620983
GO:0030507	spectrin binding	8/5085	26/18639	0.307692307692308	1.12784206943499	0.416299979402513	0.856121457620983
GO:0051139	metal cation:proton antiporter activity	8/5085	26/18639	0.307692307692308	1.12784206943499	0.416299979402513	0.856121457620983
GO:0120014	phospholipid transfer activity	8/5085	26/18639	0.307692307692308	1.12784206943499	0.416299979402513	0.856121457620983
GO:0008574	plus-end-directed microtubule motor activity	6/5085	19/18639	0.315789473684211	1.15752212389381	0.420303020506687	0.856121457620983
GO:0003720	telomerase activity	4/5085	12/18639	0.333333333333333	1.22182890855457	0.42259422639381	0.856121457620983
GO:0005078	MAP-kinase scaffold activity	4/5085	12/18639	0.333333333333333	1.22182890855457	0.42259422639381	0.856121457620983
GO:0005527	macrolide binding	4/5085	12/18639	0.333333333333333	1.22182890855457	0.42259422639381	0.856121457620983
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	4/5085	12/18639	0.333333333333333	1.22182890855457	0.42259422639381	0.856121457620983
GO:0008603	cAMP-dependent protein kinase regulator activity	4/5085	12/18639	0.333333333333333	1.22182890855457	0.42259422639381	0.856121457620983
GO:0016423	tRNA (guanine) methyltransferase activity	4/5085	12/18639	0.333333333333333	1.22182890855457	0.42259422639381	0.856121457620983
GO:0035251	UDP-glucosyltransferase activity	4/5085	12/18639	0.333333333333333	1.22182890855457	0.42259422639381	0.856121457620983
GO:0097371	MDM2/MDM4 family protein binding	4/5085	12/18639	0.333333333333333	1.22182890855457	0.42259422639381	0.856121457620983
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	4/5085	12/18639	0.333333333333333	1.22182890855457	0.42259422639381	0.856121457620983
GO:1990459	transferrin receptor binding	4/5085	12/18639	0.333333333333333	1.22182890855457	0.42259422639381	0.856121457620983
GO:0001223	transcription coactivator binding	13/5085	44/18639	0.295454545454545	1.08298471440064	0.423541233936173	0.856121457620983
GO:0016248	channel inhibitor activity	13/5085	44/18639	0.295454545454545	1.08298471440064	0.423541233936173	0.856121457620983
GO:0051117	ATPase binding	24/5085	84/18639	0.285714285714286	1.0472819216182	0.435947575377931	0.879857663548152
GO:0016849	phosphorus-oxygen lyase activity	7/5085	23/18639	0.304347826086957	1.11558291650635	0.44401166335179	0.893413453117562
GO:0140103	catalytic activity, acting on a glycoprotein	7/5085	23/18639	0.304347826086957	1.11558291650635	0.44401166335179	0.893413453117562
GO:0042169	SH2 domain binding	12/5085	41/18639	0.292682926829268	1.07282538312109	0.445666202503546	0.894672111610551
GO:0016651	oxidoreductase activity, acting on NAD(P)H	25/5085	88/18639	0.284090909090909	1.04133145615447	0.44598662577268	0.894672111610551
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/5085	16/18639	0.3125	1.14546460176991	0.452704942696627	0.901331462486078
GO:0005324	long-chain fatty acid transmembrane transporter activity	5/5085	16/18639	0.3125	1.14546460176991	0.452704942696627	0.901331462486078
GO:0008142	oxysterol binding	5/5085	16/18639	0.3125	1.14546460176991	0.452704942696627	0.901331462486078
GO:0015562	efflux transmembrane transporter activity	5/5085	16/18639	0.3125	1.14546460176991	0.452704942696627	0.901331462486078
GO:0016675	oxidoreductase activity, acting on a heme group of donors	5/5085	16/18639	0.3125	1.14546460176991	0.452704942696627	0.901331462486078
GO:0046915	transition metal ion transmembrane transporter activity	13/5085	45/18639	0.288888888888889	1.05891838741396	0.460145232366547	0.91340206305096
GO:0141110	transporter inhibitor activity	13/5085	45/18639	0.288888888888889	1.05891838741396	0.460145232366547	0.91340206305096
GO:0005385	zinc ion transmembrane transporter activity	8/5085	27/18639	0.296296296296296	1.0860701409374	0.463789886629914	0.919260672154359
GO:0016411	acylglycerol O-acyltransferase activity	9/5085	31/18639	0.290322580645161	1.06417356551527	0.480786843124182	0.951527394003979
GO:0002161	aminoacyl-tRNA editing activity	4/5085	13/18639	0.307692307692308	1.12784206943499	0.491913093861859	0.966335944386407
GO:0005542	folic acid binding	4/5085	13/18639	0.307692307692308	1.12784206943499	0.491913093861859	0.966335944386407
GO:0008253	5'-nucleotidase activity	4/5085	13/18639	0.307692307692308	1.12784206943499	0.491913093861859	0.966335944386407
GO:0035325	Toll-like receptor binding	4/5085	13/18639	0.307692307692308	1.12784206943499	0.491913093861859	0.966335944386407
GO:0089720	caspase binding	4/5085	13/18639	0.307692307692308	1.12784206943499	0.491913093861859	0.966335944386407
GO:0050699	WW domain binding	7/5085	24/18639	0.291666666666667	1.06910029498525	0.494525984995233	0.970031739798343
GO:0003777	microtubule motor activity	19/5085	68/18639	0.279411764705882	1.02418011452369	0.497339266018352	0.974109108922208
GO:0008429	phosphatidylethanolamine binding	5/5085	17/18639	0.294117647058824	1.07808433107756	0.512871021380167	0.995705672547734
GO:0016018	cyclosporin A binding	5/5085	17/18639	0.294117647058824	1.07808433107756	0.512871021380167	0.995705672547734
GO:0016805	dipeptidase activity	5/5085	17/18639	0.294117647058824	1.07808433107756	0.512871021380167	0.995705672547734
GO:0045125	bioactive lipid receptor activity	5/5085	17/18639	0.294117647058824	1.07808433107756	0.512871021380167	0.995705672547734
GO:0046965	nuclear retinoid X receptor binding	5/5085	17/18639	0.294117647058824	1.07808433107756	0.512871021380167	0.995705672547734
GO:0048038	quinone binding	5/5085	17/18639	0.294117647058824	1.07808433107756	0.512871021380167	0.995705672547734
GO:0008200	ion channel inhibitor activity	12/5085	43/18639	0.27906976744186	1.0229265280922	0.521120410799468	1
GO:0008375	acetylglucosaminyltransferase activity	12/5085	43/18639	0.27906976744186	1.0229265280922	0.521120410799468	1
GO:0140312	cargo adaptor activity	6/5085	21/18639	0.285714285714286	1.0472819216182	0.529536506790746	1
GO:0016409	palmitoyltransferase activity	10/5085	36/18639	0.277777777777778	1.01819075712881	0.536522750183335	1
GO:0002020	protease binding	37/5085	136/18639	0.272058823529412	0.997228006246746	0.540663709136145	1
GO:0044325	transmembrane transporter binding	37/5085	136/18639	0.272058823529412	0.997228006246746	0.540663709136145	1
GO:0004090	carbonyl reductase (NADPH) activity	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0005031	tumor necrosis factor receptor activity	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0015279	store-operated calcium channel activity	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0016868	intramolecular phosphotransferase activity	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0031419	cobalamin binding	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0043295	glutathione binding	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0047429	nucleoside triphosphate diphosphatase activity	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0140940	histone H2A methyltransferase activity	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:1990259	histone H2AQ104 methyltransferase activity	3/5085	10/18639	0.3	1.09964601769911	0.541682641164319	1
GO:0000030	mannosyltransferase activity	7/5085	25/18639	0.28	1.02633628318584	0.543505293587752	1
GO:0008483	transaminase activity	7/5085	25/18639	0.28	1.02633628318584	0.543505293587752	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	7/5085	25/18639	0.28	1.02633628318584	0.543505293587752	1
GO:0019707	protein-cysteine S-acyltransferase activity	7/5085	25/18639	0.28	1.02633628318584	0.543505293587752	1
GO:0003785	actin monomer binding	8/5085	29/18639	0.275862068965517	1.01116875190723	0.555618836505848	1
GO:0097110	scaffold protein binding	19/5085	70/18639	0.271428571428571	0.994917825537294	0.555831957364336	1
GO:0008559	ABC-type xenobiotic transporter activity	4/5085	14/18639	0.285714285714286	1.0472819216182	0.557445214435849	1
GO:0016530	metallochaperone activity	4/5085	14/18639	0.285714285714286	1.0472819216182	0.557445214435849	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	4/5085	14/18639	0.285714285714286	1.0472819216182	0.557445214435849	1
GO:0044548	S100 protein binding	4/5085	14/18639	0.285714285714286	1.0472819216182	0.557445214435849	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	9/5085	33/18639	0.272727272727273	0.999678197908286	0.566373871432198	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	5/5085	18/18639	0.277777777777778	1.01819075712881	0.570086530075642	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	5/5085	18/18639	0.277777777777778	1.01819075712881	0.570086530075642	1
GO:0031690	adrenergic receptor binding	5/5085	18/18639	0.277777777777778	1.01819075712881	0.570086530075642	1
GO:0035615	clathrin adaptor activity	5/5085	18/18639	0.277777777777778	1.01819075712881	0.570086530075642	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	5/5085	18/18639	0.277777777777778	1.01819075712881	0.570086530075642	1
GO:0008093	cytoskeletal anchor activity	6/5085	22/18639	0.272727272727273	0.999678197908286	0.580861337621321	1
GO:0019212	phosphatase inhibitor activity	15/5085	56/18639	0.267857142857143	0.981826801517067	0.583786051194722	1
GO:0003774	cytoskeletal motor activity	41/5085	153/18639	0.26797385620915	0.982254612759558	0.584352179793579	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	11/5085	41/18639	0.268292682926829	0.983423267860997	0.584976218828198	1
GO:0005160	transforming growth factor beta receptor binding	7/5085	26/18639	0.269230769230769	0.986861810755616	0.590370409340208	1
GO:0008157	protein phosphatase 1 binding	7/5085	26/18639	0.269230769230769	0.986861810755616	0.590370409340208	1
GO:0008198	ferrous iron binding	7/5085	26/18639	0.269230769230769	0.986861810755616	0.590370409340208	1
GO:0015216	purine nucleotide transmembrane transporter activity	7/5085	26/18639	0.269230769230769	0.986861810755616	0.590370409340208	1
GO:0043548	phosphatidylinositol 3-kinase binding	7/5085	26/18639	0.269230769230769	0.986861810755616	0.590370409340208	1
GO:0070006	metalloaminopeptidase activity	7/5085	26/18639	0.269230769230769	0.986861810755616	0.590370409340208	1
GO:0070412	R-SMAD binding	7/5085	26/18639	0.269230769230769	0.986861810755616	0.590370409340208	1
GO:0016769	transferase activity, transferring nitrogenous groups	8/5085	30/18639	0.266666666666667	0.977463126843658	0.598951814002718	1
GO:0004016	adenylate cyclase activity	3/5085	11/18639	0.272727272727273	0.999678197908286	0.613149501530668	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	3/5085	11/18639	0.272727272727273	0.999678197908286	0.613149501530668	1
GO:0008432	JUN kinase binding	3/5085	11/18639	0.272727272727273	0.999678197908286	0.613149501530668	1
GO:0008526	phosphatidylinositol transfer activity	3/5085	11/18639	0.272727272727273	0.999678197908286	0.613149501530668	1
GO:0015217	ADP transmembrane transporter activity	3/5085	11/18639	0.272727272727273	0.999678197908286	0.613149501530668	1
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	3/5085	11/18639	0.272727272727273	0.999678197908286	0.613149501530668	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	3/5085	11/18639	0.272727272727273	0.999678197908286	0.613149501530668	1
GO:0034713	type I transforming growth factor beta receptor binding	3/5085	11/18639	0.272727272727273	0.999678197908286	0.613149501530668	1
GO:0050786	RAGE receptor binding	3/5085	11/18639	0.272727272727273	0.999678197908286	0.613149501530668	1
GO:0070697	activin receptor binding	3/5085	11/18639	0.272727272727273	0.999678197908286	0.613149501530668	1
GO:1900750	oligopeptide binding	3/5085	11/18639	0.272727272727273	0.999678197908286	0.613149501530668	1
GO:0017022	myosin binding	20/5085	76/18639	0.263157894736842	0.964601769911504	0.618081542152767	1
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/5085	15/18639	0.266666666666667	0.977463126843658	0.618096531457241	1
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/5085	15/18639	0.266666666666667	0.977463126843658	0.618096531457241	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/5085	15/18639	0.266666666666667	0.977463126843658	0.618096531457241	1
GO:0047372	monoacylglycerol lipase activity	4/5085	15/18639	0.266666666666667	0.977463126843658	0.618096531457241	1
GO:0050780	dopamine receptor binding	4/5085	15/18639	0.266666666666667	0.977463126843658	0.618096531457241	1
GO:0015245	fatty acid transmembrane transporter activity	5/5085	19/18639	0.263157894736842	0.964601769911504	0.623580640635983	1
GO:0034987	immunoglobulin receptor binding	5/5085	19/18639	0.263157894736842	0.964601769911504	0.623580640635983	1
GO:0097001	ceramide binding	5/5085	19/18639	0.263157894736842	0.964601769911504	0.623580640635983	1
GO:0030276	clathrin binding	12/5085	46/18639	0.260869565217391	0.956213928434013	0.627337775433824	1
GO:0000295	adenine nucleotide transmembrane transporter activity	6/5085	23/18639	0.260869565217391	0.956213928434013	0.629161222657627	1
GO:0004602	glutathione peroxidase activity	6/5085	23/18639	0.260869565217391	0.956213928434013	0.629161222657627	1
GO:0016405	CoA-ligase activity	7/5085	27/18639	0.259259259259259	0.950311373320223	0.634673592288811	1
GO:0016782	transferase activity, transferring sulphur-containing groups	18/5085	70/18639	0.257142857142857	0.942553729456384	0.65989487536751	1
GO:0001972	retinoic acid binding	5/5085	20/18639	0.25	0.916371681415929	0.672853447233739	1
GO:0015095	magnesium ion transmembrane transporter activity	5/5085	20/18639	0.25	0.916371681415929	0.672853447233739	1
GO:0004707	MAP kinase activity	4/5085	16/18639	0.25	0.916371681415929	0.673227061044112	1
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/5085	16/18639	0.25	0.916371681415929	0.673227061044112	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	15/5085	59/18639	0.254237288135593	0.931903404829758	0.673341690523731	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	6/5085	24/18639	0.25	0.916371681415929	0.674039635211758	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	6/5085	24/18639	0.25	0.916371681415929	0.674039635211758	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	6/5085	24/18639	0.25	0.916371681415929	0.674039635211758	1
GO:0005165	neurotrophin receptor binding	3/5085	12/18639	0.25	0.916371681415929	0.676667926576287	1
GO:0008179	adenylate cyclase binding	3/5085	12/18639	0.25	0.916371681415929	0.676667926576287	1
GO:0010853	cyclase activator activity	3/5085	12/18639	0.25	0.916371681415929	0.676667926576287	1
GO:0016801	hydrolase activity, acting on ether bonds	3/5085	12/18639	0.25	0.916371681415929	0.676667926576287	1
GO:0016803	ether hydrolase activity	3/5085	12/18639	0.25	0.916371681415929	0.676667926576287	1
GO:0016840	carbon-nitrogen lyase activity	3/5085	12/18639	0.25	0.916371681415929	0.676667926576287	1
GO:0017166	vinculin binding	3/5085	12/18639	0.25	0.916371681415929	0.676667926576287	1
GO:0035259	nuclear glucocorticoid receptor binding	3/5085	12/18639	0.25	0.916371681415929	0.676667926576287	1
GO:0036009	protein-glutamine N-methyltransferase activity	3/5085	12/18639	0.25	0.916371681415929	0.676667926576287	1
GO:0042301	phosphate ion binding	3/5085	12/18639	0.25	0.916371681415929	0.676667926576287	1
GO:0070008	serine-type exopeptidase activity	3/5085	12/18639	0.25	0.916371681415929	0.676667926576287	1
GO:0070679	inositol 1,4,5 trisphosphate binding	3/5085	12/18639	0.25	0.916371681415929	0.676667926576287	1
GO:0045505	dynein intermediate chain binding	9/5085	36/18639	0.25	0.916371681415929	0.681524815161634	1
GO:0004177	aminopeptidase activity	10/5085	40/18639	0.25	0.916371681415929	0.684576436386869	1
GO:0030159	signaling receptor complex adaptor activity	13/5085	52/18639	0.25	0.916371681415929	0.694189492674036	1
GO:0005319	lipid transporter activity	46/5085	178/18639	0.258426966292135	0.947260614497365	0.694326285119416	1
GO:0030170	pyridoxal phosphate binding	14/5085	56/18639	0.25	0.916371681415929	0.697430116101966	1
GO:0023023	MHC protein complex binding	9/5085	37/18639	0.243243243243243	0.891604879215499	0.715415252181494	1
GO:0004812	aminoacyl-tRNA ligase activity	10/5085	41/18639	0.24390243902439	0.894021152600907	0.71670553882515	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	10/5085	41/18639	0.24390243902439	0.894021152600907	0.71670553882515	1
GO:0042287	MHC protein binding	10/5085	41/18639	0.24390243902439	0.894021152600907	0.71670553882515	1
GO:0008373	sialyltransferase activity	5/5085	21/18639	0.238095238095238	0.872734934681837	0.717639991122174	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	33/5085	130/18639	0.253846153846154	0.930469707283867	0.71770950016971	1
GO:1901505	carbohydrate derivative transmembrane transporter activity	13/5085	53/18639	0.245283018867925	0.8990816496911	0.722192437679124	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	4/5085	17/18639	0.235294117647059	0.862467464862051	0.722567380940711	1
GO:0019198	transmembrane receptor protein phosphatase activity	4/5085	17/18639	0.235294117647059	0.862467464862051	0.722567380940711	1
GO:0036041	long-chain fatty acid binding	4/5085	17/18639	0.235294117647059	0.862467464862051	0.722567380940711	1
GO:0004601	peroxidase activity	14/5085	57/18639	0.245614035087719	0.900294985250737	0.724333700736552	1
GO:0070279	vitamin B6 binding	14/5085	57/18639	0.245614035087719	0.900294985250737	0.724333700736552	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/5085	13/18639	0.230769230769231	0.845881552076242	0.732094376390615	1
GO:0031432	titin binding	3/5085	13/18639	0.230769230769231	0.845881552076242	0.732094376390615	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/5085	13/18639	0.230769230769231	0.845881552076242	0.732094376390615	1
GO:0061459	L-arginine transmembrane transporter activity	3/5085	13/18639	0.230769230769231	0.845881552076242	0.732094376390615	1
GO:0071837	HMG box domain binding	3/5085	13/18639	0.230769230769231	0.845881552076242	0.732094376390615	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/5085	13/18639	0.230769230769231	0.845881552076242	0.732094376390615	1
GO:0015485	cholesterol binding	13/5085	54/18639	0.240740740740741	0.882431989511635	0.748512911437675	1
GO:0001965	G-protein alpha-subunit binding	7/5085	30/18639	0.233333333333333	0.855280235988201	0.749571328229728	1
GO:0031210	phosphatidylcholine binding	7/5085	30/18639	0.233333333333333	0.855280235988201	0.749571328229728	1
GO:0016758	hexosyltransferase activity	50/5085	197/18639	0.253807106598985	0.930326580117695	0.750490090897466	1
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	6/5085	26/18639	0.230769230769231	0.845881552076242	0.752728185324131	1
GO:0050750	low-density lipoprotein particle receptor binding	6/5085	26/18639	0.230769230769231	0.845881552076242	0.752728185324131	1
GO:0016881	acid-amino acid ligase activity	5/5085	22/18639	0.227272727272727	0.833065164923572	0.757869006857719	1
GO:1990782	protein tyrosine kinase binding	29/5085	117/18639	0.247863247863248	0.908539444822631	0.759284476911829	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/5085	18/18639	0.222222222222222	0.814552605703048	0.766133338330731	1
GO:0015172	acidic amino acid transmembrane transporter activity	4/5085	18/18639	0.222222222222222	0.814552605703048	0.766133338330731	1
GO:0070064	proline-rich region binding	4/5085	18/18639	0.222222222222222	0.814552605703048	0.766133338330731	1
GO:0140359	ABC-type transporter activity	11/5085	47/18639	0.234042553191489	0.857879871963849	0.773484503760521	1
GO:0033293	monocarboxylic acid binding	19/5085	79/18639	0.240506329113924	0.881572756805198	0.777762360124658	1
GO:0004705	JUN kinase activity	3/5085	14/18639	0.214285714285714	0.785461441213654	0.779725966014642	1
GO:0005347	ATP transmembrane transporter activity	3/5085	14/18639	0.214285714285714	0.785461441213654	0.779725966014642	1
GO:0005545	1-phosphatidylinositol binding	3/5085	14/18639	0.214285714285714	0.785461441213654	0.779725966014642	1
GO:0015386	potassium:proton antiporter activity	3/5085	14/18639	0.214285714285714	0.785461441213654	0.779725966014642	1
GO:0015926	glucosidase activity	3/5085	14/18639	0.214285714285714	0.785461441213654	0.779725966014642	1
GO:0032036	myosin heavy chain binding	3/5085	14/18639	0.214285714285714	0.785461441213654	0.779725966014642	1
GO:0042043	neurexin family protein binding	3/5085	14/18639	0.214285714285714	0.785461441213654	0.779725966014642	1
GO:1901474	azole transmembrane transporter activity	3/5085	14/18639	0.214285714285714	0.785461441213654	0.779725966014642	1
GO:1901612	cardiolipin binding	3/5085	14/18639	0.214285714285714	0.785461441213654	0.779725966014642	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	7/5085	31/18639	0.225806451612903	0.827690550956323	0.781514269210435	1
GO:0004364	glutathione transferase activity	6/5085	27/18639	0.222222222222222	0.814552605703048	0.786458069048508	1
GO:0015252	proton channel activity	6/5085	27/18639	0.222222222222222	0.814552605703048	0.786458069048508	1
GO:0032934	sterol binding	16/5085	68/18639	0.235294117647059	0.862467464862051	0.795531402749986	1
GO:0032266	phosphatidylinositol-3-phosphate binding	11/5085	48/18639	0.229166666666667	0.840007374631268	0.798021717775425	1
GO:0015297	antiporter activity	33/5085	135/18639	0.244444444444444	0.896007866273353	0.798253027696459	1
GO:0005381	iron ion transmembrane transporter activity	2/5085	10/18639	0.2	0.733097345132743	0.803605942711577	1
GO:0015187	glycine transmembrane transporter activity	2/5085	10/18639	0.2	0.733097345132743	0.803605942711577	1
GO:0015643	toxic substance binding	2/5085	10/18639	0.2	0.733097345132743	0.803605942711577	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/5085	10/18639	0.2	0.733097345132743	0.803605942711577	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/5085	10/18639	0.2	0.733097345132743	0.803605942711577	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/5085	10/18639	0.2	0.733097345132743	0.803605942711577	1
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/5085	10/18639	0.2	0.733097345132743	0.803605942711577	1
GO:0019531	oxalate transmembrane transporter activity	2/5085	10/18639	0.2	0.733097345132743	0.803605942711577	1
GO:0019911	structural constituent of myelin sheath	2/5085	10/18639	0.2	0.733097345132743	0.803605942711577	1
GO:0032052	bile acid binding	2/5085	10/18639	0.2	0.733097345132743	0.803605942711577	1
GO:0141109	transporter activator activity	2/5085	10/18639	0.2	0.733097345132743	0.803605942711577	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	4/5085	19/18639	0.210526315789474	0.771681415929204	0.80414739104933	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	4/5085	19/18639	0.210526315789474	0.771681415929204	0.80414739104933	1
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/5085	19/18639	0.210526315789474	0.771681415929204	0.80414739104933	1
GO:0042800	histone H3K4 methyltransferase activity	4/5085	19/18639	0.210526315789474	0.771681415929204	0.80414739104933	1
GO:0070003	threonine-type peptidase activity	4/5085	19/18639	0.210526315789474	0.771681415929204	0.80414739104933	1
GO:0051015	actin filament binding	52/5085	209/18639	0.248803827751196	0.911987127916331	0.804788765853023	1
GO:0120015	sterol transfer activity	7/5085	32/18639	0.21875	0.801825221238938	0.810314414815633	1
GO:0030971	receptor tyrosine kinase binding	19/5085	81/18639	0.234567901234568	0.859805528242106	0.814864010208447	1
GO:0046625	sphingolipid binding	6/5085	28/18639	0.214285714285714	0.785461441213654	0.816557408536067	1
GO:0046875	ephrin receptor binding	6/5085	28/18639	0.214285714285714	0.785461441213654	0.816557408536067	1
GO:0051959	dynein light intermediate chain binding	6/5085	28/18639	0.214285714285714	0.785461441213654	0.816557408536067	1
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	6/5085	28/18639	0.214285714285714	0.785461441213654	0.816557408536067	1
GO:0004864	protein phosphatase inhibitor activity	12/5085	53/18639	0.226415094339623	0.829921522791785	0.818623016286739	1
GO:0005523	tropomyosin binding	3/5085	15/18639	0.2	0.733097345132743	0.820133324653993	1
GO:0010181	FMN binding	3/5085	15/18639	0.2	0.733097345132743	0.820133324653993	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	3/5085	15/18639	0.2	0.733097345132743	0.820133324653993	1
GO:0031005	filamin binding	3/5085	15/18639	0.2	0.733097345132743	0.820133324653993	1
GO:0120283	protein serine/threonine kinase binding	3/5085	15/18639	0.2	0.733097345132743	0.820133324653993	1
GO:0004806	triacylglycerol lipase activity	5/5085	24/18639	0.208333333333333	0.763643067846608	0.825089993852302	1
GO:0042626	ATPase-coupled transmembrane transporter activity	23/5085	98/18639	0.23469387755102	0.860267292757811	0.832029350844069	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	12/5085	54/18639	0.222222222222222	0.814552605703048	0.838654474815044	1
GO:0005506	iron ion binding	37/5085	154/18639	0.24025974025974	0.88066888863349	0.841814474833442	1
GO:0004629	phospholipase C activity	6/5085	29/18639	0.206896551724138	0.758376563930424	0.843200182525452	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/5085	29/18639	0.206896551724138	0.758376563930424	0.843200182525452	1
GO:0004180	carboxypeptidase activity	10/5085	46/18639	0.217391304347826	0.796844940361678	0.84424961295121	1
GO:0000099	sulfur amino acid transmembrane transporter activity	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0002162	dystroglycan binding	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0005114	type II transforming growth factor beta receptor binding	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0005536	D-glucose binding	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0008172	S-methyltransferase activity	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0008271	secondary active sulfate transmembrane transporter activity	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0010854	adenylate cyclase regulator activity	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0019215	intermediate filament binding	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0032050	clathrin heavy chain binding	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0045294	alpha-catenin binding	2/5085	11/18639	0.181818181818182	0.666452131938858	0.845929596307334	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	21/5085	91/18639	0.230769230769231	0.845881552076242	0.846590417323179	1
GO:0005537	D-mannose binding	5/5085	25/18639	0.2	0.733097345132743	0.852547240752648	1
GO:0015645	fatty acid ligase activity	5/5085	25/18639	0.2	0.733097345132743	0.852547240752648	1
GO:0015662	P-type ion transporter activity	5/5085	25/18639	0.2	0.733097345132743	0.852547240752648	1
GO:0120515	fatty acid-CoA ligase activity	5/5085	25/18639	0.2	0.733097345132743	0.852547240752648	1
GO:0140358	P-type transmembrane transporter activity	5/5085	25/18639	0.2	0.733097345132743	0.852547240752648	1
GO:0005149	interleukin-1 receptor binding	3/5085	16/18639	0.1875	0.687278761061947	0.854034770102427	1
GO:0005159	insulin-like growth factor receptor binding	3/5085	16/18639	0.1875	0.687278761061947	0.854034770102427	1
GO:0015385	sodium:proton antiporter activity	3/5085	16/18639	0.1875	0.687278761061947	0.854034770102427	1
GO:0008374	O-acyltransferase activity	12/5085	55/18639	0.218181818181818	0.799742558326629	0.856943684858477	1
GO:0008376	acetylgalactosaminyltransferase activity	7/5085	34/18639	0.205882352941176	0.754659031754295	0.858990107431941	1
GO:0043178	alcohol binding	21/5085	92/18639	0.228260869565217	0.836687187379761	0.860560008453004	1
GO:0005504	fatty acid binding	10/5085	47/18639	0.212765957446809	0.779890792694408	0.863375318137882	1
GO:0010314	phosphatidylinositol-5-phosphate binding	4/5085	21/18639	0.19047619047619	0.69818794774547	0.865048732504652	1
GO:0015174	basic amino acid transmembrane transporter activity	4/5085	21/18639	0.19047619047619	0.69818794774547	0.865048732504652	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	6/5085	30/18639	0.2	0.733097345132743	0.866607396099384	1
GO:0033612	receptor serine/threonine kinase binding	6/5085	30/18639	0.2	0.733097345132743	0.866607396099384	1
GO:0008194	UDP-glycosyltransferase activity	34/5085	145/18639	0.23448275862069	0.859493439121147	0.872572555258466	1
GO:0004435	phosphatidylinositol phospholipase C activity	5/5085	26/18639	0.192307692307692	0.704901293396869	0.876313682521342	1
GO:0015101	organic cation transmembrane transporter activity	18/5085	81/18639	0.222222222222222	0.814552605703048	0.876344551421611	1
GO:0016229	steroid dehydrogenase activity	7/5085	35/18639	0.2	0.733097345132743	0.879210245092763	1
GO:0004000	adenosine deaminase activity	2/5085	12/18639	0.166666666666667	0.610914454277286	0.879781930253543	1
GO:0005025	transforming growth factor beta receptor activity, type I	2/5085	12/18639	0.166666666666667	0.610914454277286	0.879781930253543	1
GO:0005026	transforming growth factor beta receptor activity, type II	2/5085	12/18639	0.166666666666667	0.610914454277286	0.879781930253543	1
GO:0005247	voltage-gated chloride channel activity	2/5085	12/18639	0.166666666666667	0.610914454277286	0.879781930253543	1
GO:0005436	sodium:phosphate symporter activity	2/5085	12/18639	0.166666666666667	0.610914454277286	0.879781930253543	1
GO:0015166	polyol transmembrane transporter activity	2/5085	12/18639	0.166666666666667	0.610914454277286	0.879781930253543	1
GO:0015368	calcium:monoatomic cation antiporter activity	2/5085	12/18639	0.166666666666667	0.610914454277286	0.879781930253543	1
GO:0016361	activin receptor activity, type I	2/5085	12/18639	0.166666666666667	0.610914454277286	0.879781930253543	1
GO:0016362	activin receptor activity, type II	2/5085	12/18639	0.166666666666667	0.610914454277286	0.879781930253543	1
GO:0017002	activin receptor activity	2/5085	12/18639	0.166666666666667	0.610914454277286	0.879781930253543	1
GO:0031543	peptidyl-proline dioxygenase activity	2/5085	12/18639	0.166666666666667	0.610914454277286	0.879781930253543	1
GO:0035497	cAMP response element binding	2/5085	12/18639	0.166666666666667	0.610914454277286	0.879781930253543	1
GO:0045295	gamma-catenin binding	2/5085	12/18639	0.166666666666667	0.610914454277286	0.879781930253543	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/5085	17/18639	0.176470588235294	0.646850598646538	0.882206353494223	1
GO:0015278	intracellularly gated calcium channel activity	3/5085	17/18639	0.176470588235294	0.646850598646538	0.882206353494223	1
GO:0017110	nucleoside diphosphate phosphatase activity	3/5085	17/18639	0.176470588235294	0.646850598646538	0.882206353494223	1
GO:0008238	exopeptidase activity	23/5085	102/18639	0.225490196078431	0.826531320492799	0.884078349814264	1
GO:0005452	solute:inorganic anion antiporter activity	6/5085	31/18639	0.193548387096774	0.709449043676848	0.887029746552732	1
GO:0070325	lipoprotein particle receptor binding	6/5085	31/18639	0.193548387096774	0.709449043676848	0.887029746552732	1
GO:0015377	chloride:monoatomic cation symporter activity	4/5085	22/18639	0.181818181818182	0.666452131938858	0.888866449315082	1
GO:0050997	quaternary ammonium group binding	8/5085	40/18639	0.2	0.733097345132743	0.890492007183701	1
GO:0071949	FAD binding	8/5085	40/18639	0.2	0.733097345132743	0.890492007183701	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	5/5085	27/18639	0.185185185185185	0.678793838085873	0.896735412856077	1
GO:0023026	MHC class II protein complex binding	5/5085	27/18639	0.185185185185185	0.678793838085873	0.896735412856077	1
GO:0004033	aldo-keto reductase (NADPH) activity	7/5085	36/18639	0.194444444444444	0.712733529990167	0.896952842847065	1
GO:0015179	L-amino acid transmembrane transporter activity	13/5085	62/18639	0.209677419354839	0.768569797316586	0.899106951601688	1
GO:0042605	peptide antigen binding	9/5085	45/18639	0.2	0.733097345132743	0.900599001171243	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/5085	32/18639	0.1875	0.687278761061947	0.904733284645908	1
GO:0017075	syntaxin-1 binding	3/5085	18/18639	0.166666666666667	0.610914454277286	0.905420956526921	1
GO:0098641	cadherin binding involved in cell-cell adhesion	3/5085	18/18639	0.166666666666667	0.610914454277286	0.905420956526921	1
GO:1901611	phosphatidylglycerol binding	3/5085	18/18639	0.166666666666667	0.610914454277286	0.905420956526921	1
GO:0140828	metal cation:monoatomic cation antiporter activity	8/5085	41/18639	0.195121951219512	0.715216922080725	0.906035634480947	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/5085	13/18639	0.153846153846154	0.563921034717495	0.906634212774076	1
GO:0017154	semaphorin receptor activity	2/5085	13/18639	0.153846153846154	0.563921034717495	0.906634212774076	1
GO:0070123	transforming growth factor beta receptor activity, type III	2/5085	13/18639	0.153846153846154	0.563921034717495	0.906634212774076	1
GO:0005158	insulin receptor binding	4/5085	23/18639	0.173913043478261	0.637475952289342	0.908918087247621	1
GO:0031681	G-protein beta-subunit binding	4/5085	23/18639	0.173913043478261	0.637475952289342	0.908918087247621	1
GO:1901682	sulfur compound transmembrane transporter activity	13/5085	63/18639	0.206349206349206	0.756370276724259	0.911201980161174	1
GO:0050698	proteoglycan sulfotransferase activity	5/5085	28/18639	0.178571428571429	0.654551201011378	0.91416541379521	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	27/5085	122/18639	0.221311475409836	0.811214275351806	0.919179536646468	1
GO:0019956	chemokine binding	6/5085	33/18639	0.181818181818182	0.666452131938858	0.919987979367297	1
GO:0016597	amino acid binding	10/5085	51/18639	0.196078431372549	0.718722887385043	0.921818119148014	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/5085	19/18639	0.157894736842105	0.578761061946903	0.92440975005397	1
GO:0022821	solute:potassium antiporter activity	3/5085	19/18639	0.157894736842105	0.578761061946903	0.92440975005397	1
GO:0031420	alkali metal ion binding	3/5085	19/18639	0.157894736842105	0.578761061946903	0.92440975005397	1
GO:0042834	peptidoglycan binding	3/5085	19/18639	0.157894736842105	0.578761061946903	0.92440975005397	1
GO:0005315	phosphate transmembrane transporter activity	4/5085	24/18639	0.166666666666667	0.610914454277286	0.925683705926685	1
GO:0015295	solute:proton symporter activity	4/5085	24/18639	0.166666666666667	0.610914454277286	0.925683705926685	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	4/5085	24/18639	0.166666666666667	0.610914454277286	0.925683705926685	1
GO:0030552	cAMP binding	4/5085	24/18639	0.166666666666667	0.610914454277286	0.925683705926685	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/5085	24/18639	0.166666666666667	0.610914454277286	0.925683705926685	1
GO:0043495	protein-membrane adaptor activity	9/5085	47/18639	0.191489361702128	0.701901713424967	0.926368046453734	1
GO:0005161	platelet-derived growth factor receptor binding	2/5085	14/18639	0.142857142857143	0.523640960809102	0.927785587233981	1
GO:0005344	oxygen carrier activity	2/5085	14/18639	0.142857142857143	0.523640960809102	0.927785587233981	1
GO:0008191	metalloendopeptidase inhibitor activity	2/5085	14/18639	0.142857142857143	0.523640960809102	0.927785587233981	1
GO:0008195	phosphatidate phosphatase activity	2/5085	14/18639	0.142857142857143	0.523640960809102	0.927785587233981	1
GO:0019763	immunoglobulin receptor activity	2/5085	14/18639	0.142857142857143	0.523640960809102	0.927785587233981	1
GO:0019992	diacylglycerol binding	2/5085	14/18639	0.142857142857143	0.523640960809102	0.927785587233981	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/5085	14/18639	0.142857142857143	0.523640960809102	0.927785587233981	1
GO:0031404	chloride ion binding	2/5085	14/18639	0.142857142857143	0.523640960809102	0.927785587233981	1
GO:0098821	BMP receptor activity	2/5085	14/18639	0.142857142857143	0.523640960809102	0.927785587233981	1
GO:0016209	antioxidant activity	18/5085	86/18639	0.209302325581395	0.76719489606915	0.929312271753311	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	29/5085	132/18639	0.21969696969697	0.805296326092786	0.932277938852242	1
GO:0051427	hormone receptor binding	6/5085	34/18639	0.176470588235294	0.646850598646538	0.933058951924873	1
GO:0005200	structural constituent of cytoskeleton	24/5085	112/18639	0.214285714285714	0.785461441213654	0.936342133331467	1
GO:0030165	PDZ domain binding	17/5085	83/18639	0.204819277108434	0.750762341401002	0.939028210241568	1
GO:0003707	nuclear steroid receptor activity	4/5085	25/18639	0.16	0.586477876106195	0.93961446119793	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/5085	25/18639	0.16	0.586477876106195	0.93961446119793	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	4/5085	25/18639	0.16	0.586477876106195	0.93961446119793	1
GO:0120020	cholesterol transfer activity	4/5085	25/18639	0.16	0.586477876106195	0.93961446119793	1
GO:0010851	cyclase regulator activity	3/5085	20/18639	0.15	0.549823008849557	0.939840139415865	1
GO:0031418	L-ascorbic acid binding	3/5085	20/18639	0.15	0.549823008849557	0.939840139415865	1
GO:0004857	enzyme inhibitor activity	100/5085	416/18639	0.240384615384615	0.881126616746086	0.94180041699709	1
GO:0004089	carbonate dehydratase activity	2/5085	15/18639	0.133333333333333	0.488731563421829	0.944347473784749	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/5085	15/18639	0.133333333333333	0.488731563421829	0.944347473784749	1
GO:0008242	omega peptidase activity	2/5085	15/18639	0.133333333333333	0.488731563421829	0.944347473784749	1
GO:0015116	sulfate transmembrane transporter activity	2/5085	15/18639	0.133333333333333	0.488731563421829	0.944347473784749	1
GO:0034483	heparan sulfate sulfotransferase activity	2/5085	15/18639	0.133333333333333	0.488731563421829	0.944347473784749	1
GO:0048306	calcium-dependent protein binding	16/5085	80/18639	0.2	0.733097345132743	0.94808357216438	1
GO:0030247	polysaccharide binding	4/5085	26/18639	0.153846153846154	0.563921034717495	0.951123693684583	1
GO:0047499	calcium-independent phospholipase A2 activity	5/5085	31/18639	0.161290322580645	0.591207536397374	0.9518776671901	1
GO:0001846	opsonin binding	3/5085	21/18639	0.142857142857143	0.523640960809102	0.952305373901067	1
GO:0019200	carbohydrate kinase activity	3/5085	21/18639	0.142857142857143	0.523640960809102	0.952305373901067	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	40/5085	181/18639	0.220994475138122	0.810052315063805	0.953679605358639	1
GO:0070888	E-box binding	11/5085	59/18639	0.186440677966102	0.68339583020849	0.954064262257997	1
GO:0001216	DNA-binding transcription activator activity	118/5085	491/18639	0.240325865580448	0.880911270118775	0.955825730963617	1
GO:0005024	transforming growth factor beta receptor activity	2/5085	16/18639	0.125	0.458185840707965	0.957249288596509	1
GO:0015378	sodium:chloride symporter activity	2/5085	16/18639	0.125	0.458185840707965	0.957249288596509	1
GO:0016722	oxidoreductase activity, acting on metal ions	2/5085	16/18639	0.125	0.458185840707965	0.957249288596509	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	2/5085	16/18639	0.125	0.458185840707965	0.957249288596509	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/5085	16/18639	0.125	0.458185840707965	0.957249288596509	1
GO:0055102	lipase inhibitor activity	2/5085	16/18639	0.125	0.458185840707965	0.957249288596509	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/5085	16/18639	0.125	0.458185840707965	0.957249288596509	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	116/5085	484/18639	0.239669421487603	0.878505083010312	0.957832703231021	1
GO:0000182	rDNA binding	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0004382	GDP phosphatase activity	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0004935	adrenergic receptor activity	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0005345	purine nucleobase transmembrane transporter activity	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0008190	eukaryotic initiation factor 4E binding	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0008239	dipeptidyl-peptidase activity	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0008519	ammonium channel activity	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0031434	mitogen-activated protein kinase kinase binding	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0035256	G protein-coupled glutamate receptor binding	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0035374	chondroitin sulfate binding	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0042166	acetylcholine binding	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0043121	neurotrophin binding	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0050308	sugar-phosphatase activity	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0070097	delta-catenin binding	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0070739	protein-glutamic acid ligase activity	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0070740	tubulin-glutamic acid ligase activity	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0071723	lipopeptide binding	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0140999	histone H3K4 trimethyltransferase activity	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:1990763	arrestin family protein binding	1/5085	10/18639	0.1	0.366548672566372	0.958689999130807	1
GO:0005516	calmodulin binding	46/5085	207/18639	0.222222222222222	0.814552605703048	0.959754185559681	1
GO:0098531	ligand-modulated transcription factor activity	11/5085	60/18639	0.183333333333333	0.672005899705015	0.960553071686979	1
GO:0015106	bicarbonate transmembrane transporter activity	5/5085	32/18639	0.15625	0.572732300884956	0.960608108401987	1
GO:0042910	xenobiotic transmembrane transporter activity	5/5085	32/18639	0.15625	0.572732300884956	0.960608108401987	1
GO:0047498	calcium-dependent phospholipase A2 activity	5/5085	32/18639	0.15625	0.572732300884956	0.960608108401987	1
GO:0019842	vitamin binding	32/5085	150/18639	0.213333333333333	0.781970501474926	0.961331773261248	1
GO:0022829	wide pore channel activity	6/5085	37/18639	0.162162162162162	0.594403252810333	0.961627052549366	1
GO:0030551	cyclic nucleotide binding	6/5085	37/18639	0.162162162162162	0.594403252810333	0.961627052549366	1
GO:0008970	phospholipase A1 activity	3/5085	22/18639	0.136363636363636	0.499839098954143	0.962322046204118	1
GO:0031683	G-protein beta/gamma-subunit complex binding	3/5085	22/18639	0.136363636363636	0.499839098954143	0.962322046204118	1
GO:0005080	protein kinase C binding	9/5085	52/18639	0.173076923076923	0.634411164057182	0.967071746640896	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/5085	17/18639	0.117647058823529	0.431233732431026	0.967255013276814	1
GO:0038191	neuropilin binding	2/5085	17/18639	0.117647058823529	0.431233732431026	0.967255013276814	1
GO:0045236	CXCR chemokine receptor binding	2/5085	17/18639	0.117647058823529	0.431233732431026	0.967255013276814	1
GO:0030296	protein tyrosine kinase activator activity	5/5085	33/18639	0.151515151515152	0.555376776615715	0.967861702872468	1
GO:0008235	metalloexopeptidase activity	12/5085	66/18639	0.181818181818182	0.666452131938858	0.968625104250288	1
GO:0005543	phospholipid binding	118/5085	497/18639	0.237424547283702	0.870276526415128	0.968959681522323	1
GO:0001851	complement component C3b binding	1/5085	11/18639	0.0909090909090909	0.333226065969429	0.969966039413154	1
GO:0003953	NAD+ nucleosidase activity	1/5085	11/18639	0.0909090909090909	0.333226065969429	0.969966039413154	1
GO:0008046	axon guidance receptor activity	1/5085	11/18639	0.0909090909090909	0.333226065969429	0.969966039413154	1
GO:0008199	ferric iron binding	1/5085	11/18639	0.0909090909090909	0.333226065969429	0.969966039413154	1
GO:0015205	nucleobase transmembrane transporter activity	1/5085	11/18639	0.0909090909090909	0.333226065969429	0.969966039413154	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/5085	11/18639	0.0909090909090909	0.333226065969429	0.969966039413154	1
GO:0019203	carbohydrate phosphatase activity	1/5085	11/18639	0.0909090909090909	0.333226065969429	0.969966039413154	1
GO:0019864	IgG binding	1/5085	11/18639	0.0909090909090909	0.333226065969429	0.969966039413154	1
GO:0034056	estrogen response element binding	1/5085	11/18639	0.0909090909090909	0.333226065969429	0.969966039413154	1
GO:0048185	activin binding	1/5085	11/18639	0.0909090909090909	0.333226065969429	0.969966039413154	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/5085	11/18639	0.0909090909090909	0.333226065969429	0.969966039413154	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/5085	11/18639	0.0909090909090909	0.333226065969429	0.969966039413154	1
GO:0005212	structural constituent of eye lens	3/5085	23/18639	0.130434782608696	0.478106964217006	0.970332640047592	1
GO:0005283	amino acid:sodium symporter activity	3/5085	23/18639	0.130434782608696	0.478106964217006	0.970332640047592	1
GO:0017134	fibroblast growth factor binding	3/5085	23/18639	0.130434782608696	0.478106964217006	0.970332640047592	1
GO:0038187	pattern recognition receptor activity	8/5085	48/18639	0.166666666666667	0.610914454277286	0.970694284513068	1
GO:0005246	calcium channel regulator activity	9/5085	53/18639	0.169811320754717	0.622441142093839	0.972205508341001	1
GO:0046982	protein heterodimerization activity	85/5085	369/18639	0.230352303523035	0.844353310789745	0.973437954218674	1
GO:0031406	carboxylic acid binding	40/5085	187/18639	0.213903743315508	0.784061331692774	0.973651070250853	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	5/5085	34/18639	0.147058823529412	0.539042165538782	0.973862177173777	1
GO:0090482	vitamin transmembrane transporter activity	5/5085	34/18639	0.147058823529412	0.539042165538782	0.973862177173777	1
GO:0051861	glycolipid binding	4/5085	29/18639	0.137931034482759	0.505584375953616	0.974617730096718	1
GO:0099604	ligand-gated calcium channel activity	4/5085	29/18639	0.137931034482759	0.505584375953616	0.974617730096718	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/5085	18/18639	0.111111111111111	0.407276302851524	0.974984270370551	1
GO:0005372	water transmembrane transporter activity	2/5085	18/18639	0.111111111111111	0.407276302851524	0.974984270370551	1
GO:0015373	monoatomic anion:sodium symporter activity	2/5085	18/18639	0.111111111111111	0.407276302851524	0.974984270370551	1
GO:0016854	racemase and epimerase activity	2/5085	18/18639	0.111111111111111	0.407276302851524	0.974984270370551	1
GO:0030228	lipoprotein particle receptor activity	2/5085	18/18639	0.111111111111111	0.407276302851524	0.974984270370551	1
GO:0032393	MHC class I receptor activity	2/5085	18/18639	0.111111111111111	0.407276302851524	0.974984270370551	1
GO:0099602	neurotransmitter receptor regulator activity	2/5085	18/18639	0.111111111111111	0.407276302851524	0.974984270370551	1
GO:0001618	virus receptor activity	15/5085	81/18639	0.185185185185185	0.678793838085873	0.975075860397104	1
GO:0005507	copper ion binding	11/5085	63/18639	0.174603174603175	0.640005618766681	0.975398628785508	1
GO:0035254	glutamate receptor binding	8/5085	49/18639	0.163265306122449	0.59844681235326	0.975482435317715	1
GO:0015149	hexose transmembrane transporter activity	3/5085	24/18639	0.125	0.458185840707965	0.976711059207722	1
GO:0019957	C-C chemokine binding	3/5085	24/18639	0.125	0.458185840707965	0.976711059207722	1
GO:0055056	D-glucose transmembrane transporter activity	3/5085	24/18639	0.125	0.458185840707965	0.976711059207722	1
GO:0004879	nuclear receptor activity	10/5085	59/18639	0.169491525423729	0.621268936553172	0.977820336975335	1
GO:0004032	aldose reductase (NADPH) activity	1/5085	12/18639	0.0833333333333333	0.305457227138643	0.9781645947913	1
GO:0004859	phospholipase inhibitor activity	1/5085	12/18639	0.0833333333333333	0.305457227138643	0.9781645947913	1
GO:0015132	prostaglandin transmembrane transporter activity	1/5085	12/18639	0.0833333333333333	0.305457227138643	0.9781645947913	1
GO:0015269	calcium-activated potassium channel activity	1/5085	12/18639	0.0833333333333333	0.305457227138643	0.9781645947913	1
GO:0016208	AMP binding	1/5085	12/18639	0.0833333333333333	0.305457227138643	0.9781645947913	1
GO:0070410	co-SMAD binding	1/5085	12/18639	0.0833333333333333	0.305457227138643	0.9781645947913	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/5085	12/18639	0.0833333333333333	0.305457227138643	0.9781645947913	1
GO:0140900	chloride:bicarbonate antiporter activity	1/5085	12/18639	0.0833333333333333	0.305457227138643	0.9781645947913	1
GO:0043177	organic acid binding	40/5085	189/18639	0.211640211640212	0.775764386383855	0.978376016574578	1
GO:0140272	exogenous protein binding	15/5085	82/18639	0.182926829268293	0.67051586445068	0.978438216119838	1
GO:0004623	phospholipase A2 activity	5/5085	35/18639	0.142857142857143	0.523640960809102	0.978805862755533	1
GO:0004620	phospholipase activity	21/5085	109/18639	0.192660550458716	0.706194690265487	0.979868389992463	1
GO:0008081	phosphoric diester hydrolase activity	16/5085	87/18639	0.183908045977011	0.674112501271488	0.980018080415805	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/5085	19/18639	0.105263157894737	0.385840707964602	0.980934213937207	1
GO:0008381	mechanosensitive monoatomic ion channel activity	2/5085	19/18639	0.105263157894737	0.385840707964602	0.980934213937207	1
GO:0042577	lipid phosphatase activity	2/5085	19/18639	0.105263157894737	0.385840707964602	0.980934213937207	1
GO:0141147	intracellularly calcium-gated channel activity	2/5085	19/18639	0.105263157894737	0.385840707964602	0.980934213937207	1
GO:0048029	monosaccharide binding	13/5085	74/18639	0.175675675675676	0.643936857211194	0.981596056151827	1
GO:0001848	complement binding	3/5085	25/18639	0.12	0.439858407079646	0.981769686209057	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	5/5085	36/18639	0.138888888888889	0.509095378564405	0.982863339353123	1
GO:0003779	actin binding	102/5085	443/18639	0.230248306997743	0.84397211290677	0.982946602831868	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	12/5085	70/18639	0.171428571428571	0.628369152970923	0.983264267774147	1
GO:0008035	high-density lipoprotein particle binding	1/5085	13/18639	0.0769230769230769	0.281960517358747	0.984125459959402	1
GO:0008417	fucosyltransferase activity	1/5085	13/18639	0.0769230769230769	0.281960517358747	0.984125459959402	1
GO:0030955	potassium ion binding	1/5085	13/18639	0.0769230769230769	0.281960517358747	0.984125459959402	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/5085	13/18639	0.0769230769230769	0.281960517358747	0.984125459959402	1
GO:0045159	myosin II binding	1/5085	13/18639	0.0769230769230769	0.281960517358747	0.984125459959402	1
GO:0070700	BMP receptor binding	1/5085	13/18639	0.0769230769230769	0.281960517358747	0.984125459959402	1
GO:0071714	icosanoid transmembrane transporter activity	1/5085	13/18639	0.0769230769230769	0.281960517358747	0.984125459959402	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/5085	13/18639	0.0769230769230769	0.281960517358747	0.984125459959402	1
GO:1902936	phosphatidylinositol bisphosphate binding	21/5085	111/18639	0.189189189189189	0.693470461612055	0.984520303014103	1
GO:0001614	purinergic nucleotide receptor activity	2/5085	20/18639	0.1	0.366548672566372	0.985500222217356	1
GO:0015464	acetylcholine receptor activity	2/5085	20/18639	0.1	0.366548672566372	0.985500222217356	1
GO:0016502	nucleotide receptor activity	2/5085	20/18639	0.1	0.366548672566372	0.985500222217356	1
GO:0030627	pre-mRNA 5'-splice site binding	2/5085	20/18639	0.1	0.366548672566372	0.985500222217356	1
GO:0033218	amide binding	53/5085	247/18639	0.214574898785425	0.786521443158611	0.985533516616095	1
GO:0019894	kinesin binding	6/5085	42/18639	0.142857142857143	0.523640960809102	0.98573370209299	1
GO:0005227	calcium-activated cation channel activity	3/5085	26/18639	0.115384615384615	0.422940776038121	0.985766989581815	1
GO:0015145	monosaccharide transmembrane transporter activity	3/5085	26/18639	0.115384615384615	0.422940776038121	0.985766989581815	1
GO:0005496	steroid binding	20/5085	108/18639	0.185185185185185	0.678793838085873	0.98722785077419	1
GO:0016298	lipase activity	25/5085	130/18639	0.192307692307692	0.704901293396869	0.987245973163842	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	15/5085	86/18639	0.174418604651163	0.639329080057625	0.988162808119328	1
GO:0005544	calcium-dependent phospholipid binding	8/5085	53/18639	0.150943396226415	0.553281015194523	0.988295182427298	1
GO:0005313	L-glutamate transmembrane transporter activity	1/5085	14/18639	0.0714285714285714	0.261820480404551	0.988459296322896	1
GO:0008392	arachidonate epoxygenase activity	1/5085	14/18639	0.0714285714285714	0.261820480404551	0.988459296322896	1
GO:0008494	translation activator activity	1/5085	14/18639	0.0714285714285714	0.261820480404551	0.988459296322896	1
GO:0042813	Wnt receptor activity	1/5085	14/18639	0.0714285714285714	0.261820480404551	0.988459296322896	1
GO:0043176	amine binding	1/5085	14/18639	0.0714285714285714	0.261820480404551	0.988459296322896	1
GO:0005109	frizzled binding	5/5085	38/18639	0.131578947368421	0.482300884955752	0.988885888968748	1
GO:0005501	retinoid binding	5/5085	38/18639	0.131578947368421	0.482300884955752	0.988885888968748	1
GO:0019840	isoprenoid binding	5/5085	38/18639	0.131578947368421	0.482300884955752	0.988885888968748	1
GO:0022804	active transmembrane transporter activity	104/5085	457/18639	0.227571115973742	0.834158904746229	0.988886311505643	1
GO:0035255	ionotropic glutamate receptor binding	3/5085	27/18639	0.111111111111111	0.407276302851524	0.988915047637914	1
GO:0072341	modified amino acid binding	16/5085	91/18639	0.175824175824176	0.64448118253428	0.988919462038912	1
GO:0036122	BMP binding	2/5085	21/18639	0.0952380952380952	0.349093973872735	0.988994416776966	1
GO:0051428	peptide hormone receptor binding	2/5085	21/18639	0.0952380952380952	0.349093973872735	0.988994416776966	1
GO:0061891	calcium ion sensor activity	2/5085	21/18639	0.0952380952380952	0.349093973872735	0.988994416776966	1
GO:0001786	phosphatidylserine binding	9/5085	59/18639	0.152542372881356	0.559142042897855	0.990461227009128	1
GO:0008013	beta-catenin binding	19/5085	106/18639	0.179245283018868	0.657021205543496	0.990994830491736	1
GO:0051119	sugar transmembrane transporter activity	3/5085	28/18639	0.107142857142857	0.392730720606827	0.991386608111746	1
GO:0005041	low-density lipoprotein particle receptor activity	1/5085	15/18639	0.0666666666666667	0.244365781710914	0.991610140789907	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/5085	15/18639	0.0666666666666667	0.244365781710914	0.991610140789907	1
GO:0015250	water channel activity	1/5085	15/18639	0.0666666666666667	0.244365781710914	0.991610140789907	1
GO:0015929	hexosaminidase activity	1/5085	15/18639	0.0666666666666667	0.244365781710914	0.991610140789907	1
GO:0033130	acetylcholine receptor binding	1/5085	15/18639	0.0666666666666667	0.244365781710914	0.991610140789907	1
GO:0045504	dynein heavy chain binding	1/5085	15/18639	0.0666666666666667	0.244365781710914	0.991610140789907	1
GO:0140161	monocarboxylate:sodium symporter activity	1/5085	15/18639	0.0666666666666667	0.244365781710914	0.991610140789907	1
GO:0033038	bitter taste receptor activity	2/5085	22/18639	0.0909090909090909	0.333226065969429	0.99166165383425	1
GO:0033691	sialic acid binding	2/5085	22/18639	0.0909090909090909	0.333226065969429	0.99166165383425	1
GO:0140784	metal ion sensor activity	2/5085	22/18639	0.0909090909090909	0.333226065969429	0.99166165383425	1
GO:0015144	carbohydrate transmembrane transporter activity	5/5085	40/18639	0.125	0.458185840707965	0.992862493480309	1
GO:0005416	amino acid:monoatomic cation symporter activity	3/5085	29/18639	0.103448275862069	0.379188281965212	0.993321478651941	1
GO:0170055	lipid transmembrane transporter activity	8/5085	56/18639	0.142857142857143	0.523640960809102	0.993441858576361	1
GO:0016493	C-C chemokine receptor activity	2/5085	23/18639	0.0869565217391304	0.318737976144671	0.993692988480599	1
GO:0008391	arachidonate monooxygenase activity	1/5085	16/18639	0.0625	0.229092920353982	0.993900864269467	1
GO:0001530	lipopolysaccharide binding	5/5085	41/18639	0.121951219512195	0.447010576300453	0.994299694966509	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	7/5085	52/18639	0.134615384615385	0.493430905377808	0.994756065325238	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/5085	30/18639	0.1	0.366548672566372	0.994832161740215	1
GO:0022839	monoatomic ion-gated channel activity	3/5085	30/18639	0.1	0.366548672566372	0.994832161740215	1
GO:0004190	aspartic-type endopeptidase activity	4/5085	36/18639	0.111111111111111	0.407276302851524	0.995012111845321	1
GO:0005126	cytokine receptor binding	57/5085	275/18639	0.207272727272727	0.759755430410298	0.995196629581107	1
GO:0005540	hyaluronic acid binding	2/5085	24/18639	0.0833333333333333	0.305457227138643	0.995236800232679	1
GO:0030215	semaphorin receptor binding	2/5085	24/18639	0.0833333333333333	0.305457227138643	0.995236800232679	1
GO:0070300	phosphatidic acid binding	2/5085	24/18639	0.0833333333333333	0.305457227138643	0.995236800232679	1
GO:0008484	sulfuric ester hydrolase activity	1/5085	17/18639	0.0588235294117647	0.215616866215513	0.995566229956508	1
GO:0008569	minus-end-directed microtubule motor activity	1/5085	17/18639	0.0588235294117647	0.215616866215513	0.995566229956508	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/5085	17/18639	0.0588235294117647	0.215616866215513	0.995566229956508	1
GO:0030169	low-density lipoprotein particle binding	1/5085	17/18639	0.0588235294117647	0.215616866215513	0.995566229956508	1
GO:0030548	acetylcholine receptor regulator activity	1/5085	17/18639	0.0588235294117647	0.215616866215513	0.995566229956508	1
GO:0008146	sulfotransferase activity	7/5085	53/18639	0.132075471698113	0.484120888295208	0.995739243157534	1
GO:0017147	Wnt-protein binding	3/5085	31/18639	0.0967741935483871	0.354724521838424	0.996008724355947	1
GO:0070001	aspartic-type peptidase activity	4/5085	37/18639	0.108108108108108	0.396268835206888	0.996082487927637	1
GO:0070851	growth factor receptor binding	25/5085	139/18639	0.179856115107914	0.659260202457503	0.99615680681789	1
GO:0042277	peptide binding	50/5085	249/18639	0.200803212851406	0.736041511177453	0.996684583687185	1
GO:0015280	ligand-gated sodium channel activity	1/5085	18/18639	0.0555555555555556	0.203638151425762	0.996776933461564	1
GO:0034185	apolipoprotein binding	1/5085	18/18639	0.0555555555555556	0.203638151425762	0.996776933461564	1
GO:0000146	microfilament motor activity	4/5085	38/18639	0.105263157894737	0.385840707964602	0.996929146628683	1
GO:0001637	G protein-coupled chemoattractant receptor activity	2/5085	26/18639	0.0769230769230769	0.281960517358747	0.997294592296389	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	2/5085	26/18639	0.0769230769230769	0.281960517358747	0.997294592296389	1
GO:0004950	chemokine receptor activity	2/5085	26/18639	0.0769230769230769	0.281960517358747	0.997294592296389	1
GO:0019865	immunoglobulin binding	2/5085	26/18639	0.0769230769230769	0.281960517358747	0.997294592296389	1
GO:0004890	GABA-A receptor activity	1/5085	19/18639	0.0526315789473684	0.192920353982301	0.99765708454625	1
GO:0005520	insulin-like growth factor binding	1/5085	19/18639	0.0526315789473684	0.192920353982301	0.99765708454625	1
GO:0030506	ankyrin binding	1/5085	19/18639	0.0526315789473684	0.192920353982301	0.99765708454625	1
GO:0043395	heparan sulfate proteoglycan binding	1/5085	19/18639	0.0526315789473684	0.192920353982301	0.99765708454625	1
GO:0046943	carboxylic acid transmembrane transporter activity	35/5085	188/18639	0.186170212765957	0.682404443607607	0.997901615656417	1
GO:0005342	organic acid transmembrane transporter activity	35/5085	189/18639	0.185185185185185	0.678793838085873	0.99815559141503	1
GO:0001540	amyloid-beta binding	12/5085	83/18639	0.144578313253012	0.529949888047766	0.99826441618566	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/5085	20/18639	0.05	0.183274336283186	0.998296919405666	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/5085	20/18639	0.05	0.183274336283186	0.998296919405666	1
GO:0008527	taste receptor activity	2/5085	28/18639	0.0714285714285714	0.261820480404551	0.99847098261963	1
GO:0045499	chemorepellent activity	2/5085	28/18639	0.0714285714285714	0.261820480404551	0.99847098261963	1
GO:0008514	organic anion transmembrane transporter activity	53/5085	269/18639	0.197026022304833	0.722196269368688	0.99850397521448	1
GO:0017080	sodium channel regulator activity	4/5085	41/18639	0.0975609756097561	0.357608461040363	0.998536739585883	1
GO:0005343	organic acid:sodium symporter activity	3/5085	35/18639	0.0857142857142857	0.314184576485461	0.998603779641016	1
GO:0004181	metallocarboxypeptidase activity	2/5085	29/18639	0.0689655172413793	0.252792187976808	0.998852427357977	1
GO:0008237	metallopeptidase activity	33/5085	184/18639	0.179347826086957	0.657397075798384	0.998902565271743	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	3/5085	36/18639	0.0833333333333333	0.305457227138643	0.99893029489517	1
GO:0038024	cargo receptor activity	8/5085	65/18639	0.123076923076923	0.451136827773996	0.998963839872317	1
GO:0001968	fibronectin binding	2/5085	30/18639	0.0666666666666667	0.244365781710914	0.999139589187817	1
GO:0015171	amino acid transmembrane transporter activity	15/5085	102/18639	0.147058823529412	0.539042165538782	0.99918658826727	1
GO:0015026	coreceptor activity	7/5085	61/18639	0.114754098360656	0.420629624256492	0.999243062045612	1
GO:0005253	monoatomic anion channel activity	15/5085	103/18639	0.145631067961165	0.533808746455881	0.99932077577448	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/5085	23/18639	0.0434782608695652	0.159368988072335	0.999345938830071	1
GO:0016917	GABA receptor activity	1/5085	23/18639	0.0434782608695652	0.159368988072335	0.999345938830071	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/5085	23/18639	0.0434782608695652	0.159368988072335	0.999345938830071	1
GO:0004175	endopeptidase activity	83/5085	405/18639	0.204938271604938	0.751198514148367	0.999408248343237	1
GO:0046906	tetrapyrrole binding	25/5085	152/18639	0.164473684210526	0.60287610619469	0.999435149938037	1
GO:0008009	chemokine activity	4/5085	45/18639	0.0888888888888889	0.325821042281219	0.999467427461629	1
GO:0071813	lipoprotein particle binding	2/5085	32/18639	0.0625	0.229092920353982	0.999517682324884	1
GO:0071814	protein-lipid complex binding	2/5085	32/18639	0.0625	0.229092920353982	0.999517682324884	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/5085	24/18639	0.0416666666666667	0.152728613569322	0.999524597029958	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/5085	24/18639	0.0416666666666667	0.152728613569322	0.999524597029958	1
GO:0004222	metalloendopeptidase activity	16/5085	110/18639	0.145454545454545	0.533161705551086	0.999531373357653	1
GO:0003730	mRNA 3'-UTR binding	49/5085	262/18639	0.187022900763359	0.685529960143214	0.999560929292609	1
GO:0016247	channel regulator activity	28/5085	168/18639	0.166666666666667	0.610914454277286	0.999586950506449	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	4/5085	46/18639	0.0869565217391304	0.318737976144671	0.999587805477271	1
GO:0042923	neuropeptide binding	2/5085	33/18639	0.0606060606060606	0.222150710646286	0.999639354541633	1
GO:0141108	transporter regulator activity	28/5085	170/18639	0.164705882352941	0.603727225403436	0.999695584852655	1
GO:0015291	secondary active transmembrane transporter activity	54/5085	287/18639	0.18815331010453	0.689673460577842	0.999699611666375	1
GO:0020037	heme binding	22/5085	142/18639	0.154929577464789	0.567892309609872	0.999712045205597	1
GO:0019825	oxygen binding	2/5085	34/18639	0.0588235294117647	0.215616866215513	0.999730550462597	1
GO:0008307	structural constituent of muscle	3/5085	42/18639	0.0714285714285714	0.261820480404551	0.999789330603174	1
GO:0098632	cell-cell adhesion mediator activity	5/5085	55/18639	0.0909090909090909	0.333226065969429	0.999797593098716	1
GO:0005104	fibroblast growth factor receptor binding	1/5085	27/18639	0.037037037037037	0.135758767617175	0.999817467647486	1
GO:0008395	steroid hydroxylase activity	1/5085	27/18639	0.037037037037037	0.135758767617175	0.999817467647486	1
GO:0005245	voltage-gated calcium channel activity	3/5085	43/18639	0.0697674418604651	0.25573163202305	0.999839934752747	1
GO:0048020	CCR chemokine receptor binding	4/5085	50/18639	0.08	0.293238938053097	0.999853936998971	1
GO:0061134	peptidase regulator activity	39/5085	226/18639	0.172566371681416	0.632539744694181	0.999861685461176	1
GO:0051393	alpha-actinin binding	1/5085	28/18639	0.0357142857142857	0.130910240202276	0.999867337463332	1
GO:0015085	calcium ion transmembrane transporter activity	22/5085	147/18639	0.149659863945578	0.548576244657155	0.999876418896483	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	3/5085	44/18639	0.0681818181818182	0.249919549477072	0.999878503462154	1
GO:0005010	insulin-like growth factor receptor activity	4/5085	51/18639	0.0784313725490196	0.287489154954017	0.999887633425049	1
GO:0005030	neurotrophin receptor activity	4/5085	51/18639	0.0784313725490196	0.287489154954017	0.999887633425049	1
GO:0030280	structural constituent of skin epidermis	2/5085	37/18639	0.0540540540540541	0.198134417603444	0.999888122382079	1
GO:0042805	actinin binding	2/5085	37/18639	0.0540540540540541	0.198134417603444	0.999888122382079	1
GO:0043394	proteoglycan binding	2/5085	37/18639	0.0540540540540541	0.198134417603444	0.999888122382079	1
GO:0019955	cytokine binding	21/5085	144/18639	0.145833333333333	0.534550147492625	0.999911128248371	1
GO:0008509	monoatomic anion transmembrane transporter activity	22/5085	149/18639	0.147651006711409	0.541212805131556	0.999912541606395	1
GO:0015459	potassium channel regulator activity	5/5085	59/18639	0.0847457627118644	0.310634468276586	0.99992591155813	1
GO:0099106	ion channel regulator activity	24/5085	160/18639	0.15	0.549823008849557	0.999929456321296	1
GO:0048019	receptor antagonist activity	1/5085	30/18639	0.0333333333333333	0.122182890855457	0.999929928910223	1
GO:0098918	structural constituent of synapse	1/5085	30/18639	0.0333333333333333	0.122182890855457	0.999929928910223	1
GO:0005003	ephrin receptor activity	4/5085	53/18639	0.0754716981132075	0.276640507597262	0.99993371084966	1
GO:0005005	transmembrane-ephrin receptor activity	4/5085	53/18639	0.0754716981132075	0.276640507597262	0.99993371084966	1
GO:0015293	symporter activity	21/5085	146/18639	0.143835616438356	0.527227542732452	0.999937657956588	1
GO:0005262	calcium channel activity	18/5085	131/18639	0.137404580152672	0.503654664595015	0.999937692826438	1
GO:0042379	chemokine receptor binding	7/5085	72/18639	0.0972222222222222	0.356366764995084	0.999939965905224	1
GO:0015294	solute:monoatomic cation symporter activity	15/5085	116/18639	0.129310344827586	0.473985352456515	0.999941900161112	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	5/5085	60/18639	0.0833333333333333	0.305457227138643	0.99994253521697	1
GO:0005004	GPI-linked ephrin receptor activity	3/5085	49/18639	0.0612244897959184	0.224417554632472	0.999969796875496	1
GO:0005008	hepatocyte growth factor receptor activity	3/5085	49/18639	0.0612244897959184	0.224417554632472	0.999969796875496	1
GO:0005009	insulin receptor activity	3/5085	49/18639	0.0612244897959184	0.224417554632472	0.999969796875496	1
GO:0005011	macrophage colony-stimulating factor receptor activity	3/5085	49/18639	0.0612244897959184	0.224417554632472	0.999969796875496	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	3/5085	49/18639	0.0612244897959184	0.224417554632472	0.999969796875496	1
GO:0005020	stem cell factor receptor activity	3/5085	49/18639	0.0612244897959184	0.224417554632472	0.999969796875496	1
GO:0008288	boss receptor activity	3/5085	49/18639	0.0612244897959184	0.224417554632472	0.999969796875496	1
GO:0036332	placental growth factor receptor activity	3/5085	49/18639	0.0612244897959184	0.224417554632472	0.999969796875496	1
GO:0038062	protein tyrosine kinase collagen receptor activity	3/5085	49/18639	0.0612244897959184	0.224417554632472	0.999969796875496	1
GO:0060175	brain-derived neurotrophic factor receptor activity	3/5085	49/18639	0.0612244897959184	0.224417554632472	0.999969796875496	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	4/5085	56/18639	0.0714285714285714	0.261820480404551	0.999970186341957	1
GO:0042056	chemoattractant activity	2/5085	42/18639	0.0476190476190476	0.174546986936367	0.999974474291864	1
GO:0098631	cell adhesion mediator activity	7/5085	76/18639	0.0921052631578947	0.337610619469027	0.999976967280287	1
GO:0005006	epidermal growth factor receptor activity	3/5085	50/18639	0.06	0.219929203539823	0.999977192186763	1
GO:0005007	fibroblast growth factor receptor activity	3/5085	50/18639	0.06	0.219929203539823	0.999977192186763	1
GO:0005017	platelet-derived growth factor receptor activity	3/5085	50/18639	0.06	0.219929203539823	0.999977192186763	1
GO:0005019	platelet-derived growth factor beta-receptor activity	3/5085	50/18639	0.06	0.219929203539823	0.999977192186763	1
GO:0005254	chloride channel activity	8/5085	83/18639	0.0963855421686747	0.353299925365178	0.99998203659983	1
GO:0005021	vascular endothelial growth factor receptor activity	3/5085	51/18639	0.0588235294117647	0.215616866215513	0.99998278960937	1
GO:0019199	transmembrane receptor protein kinase activity	7/5085	78/18639	0.0897435897435897	0.328953936918539	0.999985822374095	1
GO:0030547	signaling receptor inhibitor activity	2/5085	44/18639	0.0454545454545455	0.166613032984714	0.999985919754975	1
GO:0005518	collagen binding	6/5085	72/18639	0.0833333333333333	0.305457227138643	0.99998642498461	1
GO:0004896	cytokine receptor activity	10/5085	96/18639	0.104166666666667	0.381821533923304	0.999987030886487	1
GO:0030246	carbohydrate binding	47/5085	280/18639	0.167857142857143	0.615278128950695	0.999988632219812	1
GO:0015370	solute:sodium symporter activity	7/5085	79/18639	0.0886075949367089	0.324789963033494	0.999988893115772	1
GO:0017046	peptide hormone binding	3/5085	53/18639	0.0566037735849057	0.207480380697946	0.999990221397676	1
GO:0038064	collagen receptor activity	3/5085	53/18639	0.0566037735849057	0.207480380697946	0.999990221397676	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	3/5085	53/18639	0.0566037735849057	0.207480380697946	0.999990221397676	1
GO:0099095	ligand-gated monoatomic anion channel activity	2/5085	47/18639	0.0425531914893617	0.155978158538882	0.999994252006488	1
GO:0004497	monooxygenase activity	11/5085	106/18639	0.10377358490566	0.380380697946235	0.999995079463571	1
GO:0015103	inorganic anion transmembrane transporter activity	22/5085	165/18639	0.133333333333333	0.488731563421829	0.999995205311224	1
GO:0005178	integrin binding	21/5085	161/18639	0.130434782608696	0.478106964217006	0.999996133310049	1
GO:0140375	immune receptor activity	20/5085	156/18639	0.128205128205128	0.469934195597912	0.999996261585225	1
GO:0071855	neuropeptide receptor binding	1/5085	40/18639	0.025	0.0916371681415929	0.999997122832809	1
GO:0015108	chloride transmembrane transporter activity	13/5085	121/18639	0.107438016528926	0.393812623418416	0.999997837043745	1
GO:0008227	G protein-coupled amine receptor activity	1/5085	41/18639	0.024390243902439	0.0894021152600907	0.999997909455486	1
GO:0042562	hormone binding	8/5085	94/18639	0.0851063829787234	0.311956317077763	0.999998732346079	1
GO:0098960	postsynaptic neurotransmitter receptor activity	4/5085	69/18639	0.0579710144927536	0.212491984096447	0.999999141855536	1
GO:0022824	transmitter-gated monoatomic ion channel activity	3/5085	63/18639	0.0476190476190476	0.174546986936367	0.999999441994462	1
GO:0022835	transmitter-gated channel activity	3/5085	63/18639	0.0476190476190476	0.174546986936367	0.999999441994462	1
GO:0061135	endopeptidase regulator activity	23/5085	184/18639	0.125	0.458185840707965	0.999999666763865	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	4/5085	73/18639	0.0547945205479452	0.200848587707601	0.999999718473055	1
GO:0019838	growth factor binding	14/5085	136/18639	0.102941176470588	0.377329515877147	0.999999727027888	1
GO:0008188	neuropeptide receptor activity	1/5085	48/18639	0.0208333333333333	0.0763643067846608	0.999999776604939	1
GO:0016500	protein-hormone receptor activity	3/5085	67/18639	0.0447761194029851	0.164126271298375	0.999999825077877	1
GO:0005272	sodium channel activity	1/5085	51/18639	0.0196078431372549	0.0718722887385043	0.999999914351618	1
GO:1901681	sulfur compound binding	39/5085	275/18639	0.141818181818182	0.519832662912309	0.999999945529534	1
GO:0001664	G protein-coupled receptor binding	42/5085	297/18639	0.141414141414141	0.518351658174667	0.999999984492022	1
GO:0008083	growth factor activity	16/5085	162/18639	0.0987654320987654	0.362023380312466	0.999999989577794	1
GO:0004866	endopeptidase inhibitor activity	15/5085	161/18639	0.093167701863354	0.341504974440719	0.99999999656407	1
GO:0003823	antigen binding	17/5085	174/18639	0.0977011494252874	0.358122266300478	0.999999997451512	1
GO:0030414	peptidase inhibitor activity	16/5085	169/18639	0.0946745562130177	0.34702832905692	0.999999997891848	1
GO:0004867	serine-type endopeptidase inhibitor activity	4/5085	95/18639	0.0421052631578947	0.154336283185841	0.999999999466394	1
GO:0050840	extracellular matrix binding	1/5085	67/18639	0.0149253731343284	0.0547087570994585	0.999999999486164	1
GO:0030594	neurotransmitter receptor activity	4/5085	97/18639	0.0412371134020619	0.151154091779947	0.999999999701014	1
GO:0001653	peptide receptor activity	8/5085	128/18639	0.0625	0.229092920353982	0.99999999979588	1
GO:0017171	serine hydrolase activity	19/5085	198/18639	0.095959595959596	0.351738625189953	0.999999999847624	1
GO:0099094	ligand-gated monoatomic cation channel activity	9/5085	136/18639	0.0661764705882353	0.242568974492452	0.999999999850152	1
GO:0008236	serine-type peptidase activity	18/5085	194/18639	0.0927835051546392	0.340096706504881	0.999999999900698	1
GO:0004252	serine-type endopeptidase activity	15/5085	176/18639	0.0852272727272727	0.312399436846339	0.999999999900802	1
GO:0015081	sodium ion transmembrane transporter activity	13/5085	164/18639	0.0792682926829268	0.290556874595295	0.999999999909811	1
GO:0015079	potassium ion transmembrane transporter activity	12/5085	160/18639	0.075	0.274911504424779	0.999999999949849	1
GO:0005179	hormone activity	7/5085	132/18639	0.053030303030303	0.1943818718155	0.999999999989941	1
GO:0005244	voltage-gated monoatomic ion channel activity	13/5085	173/18639	0.0751445086705202	0.275441199038314	0.999999999990405	1
GO:0022832	voltage-gated channel activity	13/5085	175/18639	0.0742857142857143	0.272293299620733	0.999999999994196	1
GO:0008528	G protein-coupled peptide receptor activity	5/5085	122/18639	0.040983606557377	0.15022486580589	0.999999999997758	1
GO:0005249	voltage-gated potassium channel activity	2/5085	98/18639	0.0204081632653061	0.0748058515441575	0.999999999999046	1
GO:0005125	cytokine activity	21/5085	234/18639	0.0897435897435897	0.328953936918539	0.999999999999435	1
GO:0022834	ligand-gated channel activity	13/5085	188/18639	0.0691489361702128	0.253464507625683	0.999999999999788	1
GO:0005267	potassium channel activity	4/5085	124/18639	0.032258064516129	0.118241507279475	0.999999999999893	1
GO:0015276	ligand-gated monoatomic ion channel activity	12/5085	186/18639	0.0645161290322581	0.236483014558949	0.999999999999937	1
GO:0022843	voltage-gated monoatomic cation channel activity	6/5085	143/18639	0.041958041958042	0.153796645832044	0.999999999999946	1
GO:0030527	structural constituent of chromatin	1/5085	98/18639	0.0102040816326531	0.0374029257720787	0.999999999999975	1
GO:0005549	odorant binding	1/5085	111/18639	0.00900900900900901	0.0330224029339074	1	1
GO:0046873	metal ion transmembrane transporter activity	54/5085	450/18639	0.12	0.439858407079646	1	1
GO:0008201	heparin binding	7/5085	172/18639	0.0406976744186047	0.149176785346779	1	1
GO:0004984	olfactory receptor activity	2/5085	419/18639	0.00477326968973747	0.0174963566857457	1	1
GO:0005201	extracellular matrix structural constituent	4/5085	168/18639	0.0238095238095238	0.0872734934681837	1	1
GO:0005216	monoatomic ion channel activity	48/5085	448/18639	0.107142857142857	0.392730720606827	1	1
GO:0005261	monoatomic cation channel activity	32/5085	341/18639	0.093841642228739	0.343975293903927	1	1
GO:0005539	glycosaminoglycan binding	14/5085	242/18639	0.0578512396694215	0.212052951071455	1	1
GO:0022836	gated channel activity	24/5085	318/18639	0.0754716981132075	0.276640507597262	1	1
GO:0030371	translation repressor activity	11/5085	329/18639	0.033434650455927	0.122554267423407	1	1
GO:0045182	translation regulator activity	14/5085	356/18639	0.0393258426966292	0.144148354380034	1	1