category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	3/34	32/9376	25.8529411764706	PCCA/LDHB/LDHA	8.4955506100493
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	4/34	94/9376	11.7346683354193	CCL20/NFKBIA/IL17RB/CXCL2	6.31011015527402
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	5/34	216/9376	6.38344226579521	CYP2C9/SOD2/NFKBIA/LBP/CXCL2	4.82885721457386
Organismal Systems	Digestive system	hsa04978	Mineral absorption	3/34	61/9376	13.5621986499518	FXYD2/MT2A/MT1M	5.93805628592532
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	2/34	29/9376	19.0182555780933	MOB1B/RASSF6	5.86247205677058
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	3/34	105/9376	7.87899159663866	NFKBIA/LBP/CXCL2	4.27623243366602
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	3/34	119/9376	6.95205140879881	CCL20/NFKBIA/CXCL2	3.94194161630789
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	2/34	47/9376	11.7346683354193	LDHB/LDHA	4.45066778869604
NA	NA	hsa03272	Virion - Hepatitis viruses	2/34	48/9376	11.4901960784314	CLDN14/CLDN4	4.39556919546278
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	3/34	144/9376	5.74509803921569	NFKBIA/LBP/CXCL2	3.46165436871202
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	2/34	54/9376	10.2135076252723	LDHB/LDHA	4.09611834205905
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	2/34	56/9376	9.84873949579832	NFKBIA/CXCL2	4.00656905466821
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	3/34	156/9376	5.30316742081448	CLDN14/NFKBIA/CLDN4	3.26956704359701
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	3/34	157/9376	5.26938928437617	MOB1B/ID1/RASSF6	3.25445926275474
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/34	62/9376	8.89563567362429	SOD2/CRYAB	3.7628767516441
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	2/34	67/9376	8.23178226514486	LDHB/LDHA	3.58373916853417
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	2/34	70/9376	7.87899159663866	CYP2C9/MGST3	3.48495713041798
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/34	71/9376	7.76801988400994	NFKBIA/CXCL2	3.45332757752917
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	2/34	71/9376	7.76801988400994	LDHB/LDHA	3.45332757752917
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	2/34	73/9376	7.55519742143433	CYP2C9/MGST3	3.39188297939286
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/34	75/9376	7.35372549019608	MGST3/PMAIP1	3.33272456144828
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	3/34	193/9376	4.28649801889668	CCL20/NFKBIA/CXCL2	2.78307495059245
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	2/34	79/9376	6.98138495904691	CYP2C9/MGST3	3.22069092607031
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	3/34	196/9376	4.22088835534214	NFKBIA/UBC/CXCL2	2.74908097045843
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/34	200/9376	4.13647058823529	CLDN14/NFKBIA/CLDN4	2.70479702447422
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/34	90/9376	6.1281045751634	BATF3/NFKBIA	2.94896048549735
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/34	95/9376	5.80557275541796	CCL20/CXCL2	2.83997644719156
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	3/34	227/9376	3.6444674786214	SOD2/NFKBIA/MGST3	2.43315351376682
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/34	100/9376	5.51529411764706	CCL20/CXCL2	2.73848798580058
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	2/34	107/9376	5.1544804837823	LDHB/LDHA	2.60733801174556
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	2/34	109/9376	5.05990286022666	NFKBIA/LBP	2.57196157053582
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/34	110/9376	5.01390374331551	LDHB/LDHA	2.55459650358285
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/34	110/9376	5.01390374331551	ID3/ID1	2.55459650358285
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/34	115/9376	4.79590792838875	CYP2C9/SLC18A2	2.470818322295
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/34	116/9376	4.75456389452333	CLDN14/CLDN4	2.45464202870576
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	2/34	120/9376	4.59607843137255	NFKBIA/NTF3	2.39173616537478
Organismal Systems	Excretory system	hsa04964	Proximal tubule bicarbonate reclamation	1/34	23/9376	11.9897698209719	FXYD2	3.18333403337629
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/34	137/9376	4.02576212966939	NFKBIA/PMAIP1	2.15222537874907
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	3/34	298/9376	2.7761547572049	CCL20/IL17RB/CXCL2	1.87974531661689
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/34	144/9376	3.83006535947712	ID3/ID1	2.06459551191778
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	1/34	30/9376	9.1921568627451	CYP2C9	2.71113512578546
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/34	31/9376	8.89563567362429	PCCA	2.65633876338408
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/34	32/9376	8.61764705882353	PMAIP1	2.60396166627547
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/34	160/9376	3.44705882352941	CLDN14/CLDN4	1.88338164157756
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	2/34	170/9376	3.24429065743945	CLDN14/CLDN4	1.78144837863203
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/34	38/9376	7.25696594427245	NNMT	2.33149141125672
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/34	38/9376	7.25696594427245	FXYD2	2.33149141125672
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	2/34	174/9376	3.16970926301555	YOD1/CRYAB	1.74277057234514
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/34	187/9376	2.94935514312677	NFKBIA/CXCL2	1.62436196202409
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/34	44/9376	6.26737967914439	AQP3	2.11270452451728
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/34	45/9376	6.1281045751634	DEFB1	2.08019572916788
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	1/34	48/9376	5.74509803921569	PCCA	1.98827615944298
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/34	48/9376	5.74509803921569	FXYD2	1.98827615944298
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/34	49/9376	5.62785114045618	SLC18A2	1.95934808989279
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	2/34	205/9376	2.69038737446198	NFKBIA/PMAIP1	1.47625026762012
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/34	53/9376	5.2031076581576	FXYD2	1.85112511058991
NA	NA	hsa04382	Cornified envelope formation	2/34	217/9376	2.54161019246408	CLDN14/CLDN4	1.38607131459424
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/34	59/9376	4.67397806580259	MGST3	1.7077711889639
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/34	226/9376	2.44039562727746	NFKBIA/FXYD2	1.32230193073851
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/34	63/9376	4.37721755368814	CYP2C9	1.62251857130544
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/34	68/9376	4.05536332179931	CYP2C9	1.52543706662827
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/34	69/9376	3.99658994032396	SLC18A2	1.50713505336824
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/34	70/9376	3.93949579831933	NFKBIA	1.48917420500881
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/34	250/9376	2.20611764705882	NAPSA/NCOA7	1.16606996496861
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/34	72/9376	3.83006535947712	NFKBIA	1.45422976048043
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/34	253/9376	2.17995814926761	NFKBIA/UBC	1.14779199736143
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/34	75/9376	3.67686274509804	PMAIP1	1.40409689275682
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/34	75/9376	3.67686274509804	FXYD2	1.40409689275682
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/34	76/9376	3.62848297213622	UBC	1.38795586059867
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/34	77/9376	3.58135981665393	NFKBIA	1.37208478725969
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/34	78/9376	3.53544494720965	BTG2	1.35647527058173
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/34	78/9376	3.53544494720965	NFKBIA	1.35647527058173
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/34	79/9376	3.49069247952345	SLC18A2	1.3411192764478
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	2/34	268/9376	2.05794556628622	SLC18A2/UBC	1.06004517626904
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/34	82/9376	3.36298421807748	MGST3	1.29649718585459
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/34	83/9376	3.32246633593196	SOD2	1.28208160915804
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/34	83/9376	3.32246633593196	NFKBIA	1.28208160915804
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/34	86/9376	3.20656634746922	FXYD2	1.24011946509473
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	1/34	87/9376	3.16970926301555	FXYD2	1.22654038748558
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/34	87/9376	3.16970926301555	PMAIP1	1.22654038748558
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/34	90/9376	3.0640522875817	SOD2	1.18695095758356
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/34	90/9376	3.0640522875817	FXYD2	1.18695095758356
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/34	91/9376	3.03038138332256	NFKBIA	1.17412011940079
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/34	93/9376	2.9652118912081	NFKBIA	1.14897835578995
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/34	93/9376	2.9652118912081	FXYD2	1.14897835578995
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/34	93/9376	2.9652118912081	NFKBIA	1.14897835578995
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/34	300/9376	1.83843137254902	DUSP5/NTF3	0.890401882332445
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/34	99/9376	2.78550207961973	DEFB1	1.07740588795454
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/34	102/9376	2.70357554786621	FXYD2	1.04359767573131
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/34	103/9376	2.67732724157624	FXYD2	1.03259840087601
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/34	103/9376	2.67732724157624	NFKBIA	1.03259840087601
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/34	103/9376	2.67732724157624	CXCL2	1.03259840087601
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/34	105/9376	2.62633053221289	UBC	1.01098646102553
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/34	105/9376	2.62633053221289	NFKBIA	1.01098646102553
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/34	106/9376	2.6015538290788	NFKBIA	1.00036795381638
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/34	109/9376	2.52995143011333	NFKBIA	0.969229170871865
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/34	109/9376	2.52995143011333	NFKBIA	0.969229170871865
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/34	112/9376	2.46218487394958	NFKBIA	0.93911156810422
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/34	116/9376	2.37728194726166	PCCA	0.900433245538203
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/34	122/9376	2.26036644165863	NFKBIA	0.845312252941774
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/34	122/9376	2.26036644165863	FXYD2	0.845312252941774
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/34	130/9376	2.12126696832579	NFKBIA	0.77662063415708
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/34	133/9376	2.0734188412207	SOD2	0.752131405548803
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/34	133/9376	2.0734188412207	SLC18A2	0.752131405548803
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/34	136/9376	2.02768166089965	NFKBIA	0.728278083011644
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/34	138/9376	1.99829497016198	NFKBIA	0.712712888368271
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/34	142/9376	1.94200497100249	UBC	0.682350630092204
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/34	142/9376	1.94200497100249	NFKBIA	0.682350630092204
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/34	142/9376	1.94200497100249	MGST3	0.682350630092204
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/34	154/9376	1.79067990832697	FXYD2	0.596834156976541
NA	NA	hsa04519	Cadherin signaling	2/34	404/9376	1.36517181129878	MOB1B/NFKBIA	0.452635342141646
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/34	157/9376	1.75646309479206	DUSP5	0.576634774155491
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/34	163/9376	1.69180801154818	NFKBIA	0.537506869405836
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/34	166/9376	1.66123316796598	FXYD2	0.518542102383347
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/34	169/9376	1.63174382178907	UBC	0.49995446272056
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/34	170/9376	1.62214532871972	MGST3	0.493839683129879
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/34	173/9376	1.59401564093846	NFKBIA	0.475730927760697
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/34	180/9376	1.53202614379085	NFKBIA	0.434785358378735
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/34	181/9376	1.52356191095223	LBP	0.4290783778309
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/34	191/9376	1.44379427163536	SLC18A2	0.373821228799141
NA	NA	hsa04082	Neuroactive ligand signaling	1/34	199/9376	1.3857522908661	SLC18A2	0.331810291053044
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/34	205/9376	1.34519368723099	NFKBIA	0.301464788991173
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/34	212/9376	1.3007769145394	ID1	0.267223750683066
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/34	214/9376	1.28862012094557	NFKBIA	0.257657929497959
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/34	217/9376	1.27080509623204	MGST3	0.243482546734595
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	1/34	224/9376	1.23109243697479	NFKBIA	0.211182001252287
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/34	227/9376	1.2148224928738	NFKBIA	0.197656468683263
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/34	238/9376	1.1586752347998	NTF3	0.149581270111815
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	1/34	238/9376	1.1586752347998	NFKBIA	0.149581270111815
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/34	248/9376	1.11195445920304	NFKBIA	0.107791517592652
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	1/34	308/9376	0.895339954163484	SOD2	-0.112669323936253
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	1/34	362/9376	0.761780955476113	NTF3	-0.278854175585576
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	1/34	480/9376	0.574509803921569	UBC	-0.577321796742146