ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0140662	ATP-dependent protein folding chaperone	9/289	40/18639	0.225	14.5113321799308	8.2081138205041e-09	5.17931982073809e-06
GO:0044183	protein folding chaperone	11/289	75/18639	0.146666666666667	9.45923875432526	2.09239667779392e-08	6.60151151843981e-06
GO:0051082	unfolded protein binding	12/289	121/18639	0.0991735537190083	6.39617947324773	4.00051297069922e-07	8.41441228170402e-05
GO:0031625	ubiquitin protein ligase binding	14/289	302/18639	0.0463576158940397	2.98982561470245	0.000279977758029284	0.0441664913291195
GO:0044389	ubiquitin-like protein ligase binding	14/289	322/18639	0.0434782608695652	2.8041221603731	0.000532129568175536	0.0671547515037527
GO:0097718	disordered domain specific binding	4/289	28/18639	0.142857142857143	9.2135442412259	0.00086420070985508	0.0855155954444517
GO:0031072	heat shock protein binding	8/289	131/18639	0.0610687022900763	3.9386143321271	0.00101200309581874	0.0855155954444517
GO:0019003	GDP binding	6/289	75/18639	0.08	5.15958477508651	0.00108419138439875	0.0855155954444517
GO:0001221	transcription coregulator binding	7/289	115/18639	0.0608695652173913	3.92577102452234	0.00211142418977937	0.144150048729756
GO:0016887	ATP hydrolysis activity	15/289	417/18639	0.0359712230215827	2.31995718304249	0.00228446986893433	0.144150048729756
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	7/289	128/18639	0.0546875	3.52705990484429	0.00384561259653214	0.195741810673111
GO:0051879	Hsp90 protein binding	4/289	42/18639	0.0952380952380952	6.14236282748394	0.00398678417846095	0.195741810673111
GO:0002039	p53 binding	5/289	69/18639	0.072463768115942	4.67353693395517	0.00433315859852472	0.195741810673111
GO:0048156	tau protein binding	4/289	43/18639	0.0930232558139535	5.99951718033315	0.00434292448403098	0.195741810673111
GO:0140693	molecular condensate scaffold activity	4/289	48/18639	0.0833333333333333	5.37456747404844	0.00644690881220562	0.245654881547761
GO:0017022	myosin binding	5/289	76/18639	0.0657894736842105	4.24307958477509	0.00652760796530689	0.245654881547761
GO:0060590	ATPase regulator activity	4/289	49/18639	0.0816326530612245	5.26488242355766	0.00693598285405043	0.245654881547761
GO:0016853	isomerase activity	8/289	180/18639	0.0444444444444444	2.86643598615917	0.00715684170147292	0.245654881547761
GO:0001671	ATPase activator activity	3/289	27/18639	0.111111111111111	7.16608996539792	0.00819371653285282	0.245654881547761
GO:0016860	intramolecular oxidoreductase activity	4/289	53/18639	0.0754716981132075	4.86753280668538	0.00913597995785866	0.245654881547761
GO:0003925	G protein activity	4/289	54/18639	0.0740740740740741	4.77739331026528	0.00974914184817413	0.245654881547761
GO:0001094	TFIID-class transcription factor complex binding	2/289	10/18639	0.2	12.8989619377163	0.00993086225785607	0.245654881547761
GO:0005528	FK506 binding	2/289	10/18639	0.2	12.8989619377163	0.00993086225785607	0.245654881547761
GO:0000287	magnesium ion binding	9/289	230/18639	0.0391304347826087	2.52370994433579	0.00993421873713687	0.245654881547761
GO:0004181	metallocarboxypeptidase activity	3/289	29/18639	0.103448275862069	6.671876864336	0.0100059015505571	0.245654881547761
GO:0061980	regulatory RNA binding	4/289	58/18639	0.0689655172413793	4.44791790955733	0.0124668371663306	0.245654881547761
GO:0120015	sterol transfer activity	3/289	32/18639	0.09375	6.0463884083045	0.0131279882970814	0.245654881547761
GO:0036002	pre-mRNA binding	4/289	59/18639	0.0677966101694915	4.37252947041229	0.0132144136354317	0.245654881547761
GO:0001098	basal transcription machinery binding	4/289	60/18639	0.0666666666666667	4.29965397923875	0.0139899574023758	0.245654881547761
GO:0001099	basal RNA polymerase II transcription machinery binding	4/289	60/18639	0.0666666666666667	4.29965397923875	0.0139899574023758	0.245654881547761
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	4/289	60/18639	0.0666666666666667	4.29965397923875	0.0139899574023758	0.245654881547761
GO:0005527	macrolide binding	2/289	12/18639	0.166666666666667	10.7491349480969	0.0142709254622337	0.245654881547761
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	3/289	33/18639	0.0909090909090909	5.86316451714376	0.0142782557226976	0.245654881547761
GO:0071889	14-3-3 protein binding	3/289	33/18639	0.0909090909090909	5.86316451714376	0.0142782557226976	0.245654881547761
GO:0140416	transcription regulator inhibitor activity	3/289	33/18639	0.0909090909090909	5.86316451714376	0.0142782557226976	0.245654881547761
GO:0042826	histone deacetylase binding	6/289	127/18639	0.047244094488189	3.0469988829251	0.0143262964494922	0.245654881547761
GO:0019207	kinase regulator activity	10/289	287/18639	0.0348432055749129	2.24720591249412	0.0144464761515414	0.245654881547761
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	4/289	61/18639	0.0655737704918033	4.22916784843156	0.014793796353114	0.245654881547761
GO:0035403	histone H3T6 kinase activity	9/289	247/18639	0.0364372469635627	2.35001330849082	0.0152473609218775	0.246694480556531
GO:0019887	protein kinase regulator activity	9/289	255/18639	0.0352941176470588	2.27628740077346	0.018368239363678	0.260189092945001
GO:0008235	metalloexopeptidase activity	4/289	66/18639	0.0606060606060606	3.9087763447625	0.0192478788550863	0.260189092945001
GO:0004721	phosphoprotein phosphatase activity	7/289	175/18639	0.04	2.57979238754325	0.019571222799188	0.260189092945001
GO:0030695	GTPase regulator activity	14/289	489/18639	0.0286298568507157	1.84647716899824	0.0208634357583522	0.260189092945001
GO:0043531	ADP binding	3/289	38/18639	0.0789473684210526	5.0916955017301	0.0208650497831334	0.260189092945001
GO:0060589	nucleoside-triphosphatase regulator activity	14/289	490/18639	0.0285714285714286	1.84270884824518	0.021188110971772	0.260189092945001
GO:0032934	sterol binding	4/289	68/18639	0.0588235294117647	3.79381233462243	0.0212374283096726	0.260189092945001
GO:0004722	protein serine/threonine phosphatase activity	5/289	103/18639	0.0485436893203883	3.13081600430006	0.022139023695353	0.260189092945001
GO:0140996	histone H3 kinase activity	11/289	357/18639	0.030812324929972	1.98723503242127	0.0240331649536885	0.260189092945001
GO:0005159	insulin-like growth factor receptor binding	2/289	16/18639	0.125	8.06185121107266	0.0249130199039003	0.260189092945001
GO:0030275	LRR domain binding	2/289	16/18639	0.125	8.06185121107266	0.0249130199039003	0.260189092945001
GO:0035173	histone kinase activity	11/289	360/18639	0.0305555555555556	1.97067474048443	0.0253510195996645	0.260189092945001
GO:0008137	NADH dehydrogenase (ubiquinone) activity	3/289	41/18639	0.0731707317073171	4.71913241623766	0.0254904895767919	0.260189092945001
GO:0042169	SH2 domain binding	3/289	41/18639	0.0731707317073171	4.71913241623766	0.0254904895767919	0.260189092945001
GO:0061650	ubiquitin-like protein conjugating enzyme activity	3/289	41/18639	0.0731707317073171	4.71913241623766	0.0254904895767919	0.260189092945001
GO:0005096	GTPase activator activity	9/289	271/18639	0.033210332103321	2.14189404869827	0.0259632153128846	0.260189092945001
GO:0035198	miRNA binding	3/289	42/18639	0.0714285714285714	4.60677212061295	0.0271446207612789	0.260189092945001
GO:0043175	RNA polymerase core enzyme binding	3/289	42/18639	0.0714285714285714	4.60677212061295	0.0271446207612789	0.260189092945001
GO:0031489	myosin V binding	2/289	17/18639	0.117647058823529	7.58762466924486	0.0279500637323444	0.260189092945001
GO:0051787	misfolded protein binding	2/289	17/18639	0.117647058823529	7.58762466924486	0.0279500637323444	0.260189092945001
GO:0003725	double-stranded RNA binding	4/289	75/18639	0.0533333333333333	3.439723183391	0.0291676649298454	0.260189092945001
GO:0001223	transcription coactivator binding	3/289	44/18639	0.0681818181818182	4.39737338785782	0.0306207118987126	0.260189092945001
GO:0003954	NADH dehydrogenase activity	3/289	44/18639	0.0681818181818182	4.39737338785782	0.0306207118987126	0.260189092945001
GO:0043014	alpha-tubulin binding	3/289	44/18639	0.0681818181818182	4.39737338785782	0.0306207118987126	0.260189092945001
GO:0008409	5'-3' exonuclease activity	2/289	18/18639	0.111111111111111	7.16608996539792	0.0311271908404252	0.260189092945001
GO:0003924	GTPase activity	10/289	331/18639	0.0302114803625378	1.94848367639218	0.0343118513605139	0.260189092945001
GO:0004180	carboxypeptidase activity	3/289	46/18639	0.0652173913043478	4.20618324055965	0.0343193211197793	0.260189092945001
GO:0005525	GTP binding	11/289	378/18639	0.0291005291005291	1.87683308617565	0.0343802038747604	0.260189092945001
GO:1990782	protein tyrosine kinase binding	5/289	117/18639	0.0427350427350427	2.75618844822997	0.0356837505055995	0.260189092945001
GO:0045296	cadherin binding	10/289	334/18639	0.029940119760479	1.93098232600543	0.0361404249086562	0.260189092945001
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	8/289	243/18639	0.0329218106995885	2.12328591567346	0.0362220442712401	0.260189092945001
GO:0030971	receptor tyrosine kinase binding	4/289	81/18639	0.0493827160493827	3.18492887351019	0.0371896702840085	0.260189092945001
GO:0004676	3-phosphoinositide-dependent protein kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0004711	ribosomal protein S6 kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0035175	histone H3S10 kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0035979	histone H2AXS139 kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0044022	histone H3S28 kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0044023	histone H4S1 kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0044024	histone H2AS1 kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0044025	histone H2BS14 kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0072354	histone H3T3 kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0072371	histone H2AS121 kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0072518	Rho-dependent protein serine/threonine kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0140823	histone H2BS36 kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0140855	histone H3S57 kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0140995	histone H2A kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0140997	histone H4 kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0140998	histone H2B kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:1990244	histone H2AT120 kinase activity	8/289	245/18639	0.0326530612244898	2.10595296942306	0.0377264437329303	0.260189092945001
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	3/289	48/18639	0.0625	4.03092560553633	0.0382384315812163	0.260189092945001
GO:0004677	DNA-dependent protein kinase activity	8/289	246/18639	0.032520325203252	2.09739218499451	0.0384941663258578	0.260189092945001
GO:0140857	histone H3T45 kinase activity	8/289	246/18639	0.032520325203252	2.09739218499451	0.0384941663258578	0.260189092945001
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	4/289	82/18639	0.0487804878048781	3.14608827749177	0.0386380046673375	0.260189092945001
GO:0035402	histone H3T11 kinase activity	8/289	247/18639	0.0323886639676113	2.0889007186585	0.0392723020715977	0.260189092945001
GO:0004679	AMP-activated protein kinase activity	8/289	248/18639	0.032258064516129	2.08047773188972	0.0400608980357172	0.260189092945001
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	4/289	83/18639	0.0481927710843374	3.1081835994497	0.0401182507513356	0.260189092945001
GO:0001222	transcription corepressor binding	3/289	49/18639	0.0612244897959184	3.94866181766824	0.0402798956286401	0.260189092945001
GO:0016763	pentosyltransferase activity	3/289	49/18639	0.0612244897959184	3.94866181766824	0.0402798956286401	0.260189092945001
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	2/289	21/18639	0.0952380952380952	6.14236282748394	0.0414492573973124	0.260189092945001
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/289	21/18639	0.0952380952380952	6.14236282748394	0.0414492573973124	0.260189092945001
GO:0070182	DNA polymerase binding	2/289	21/18639	0.0952380952380952	6.14236282748394	0.0414492573973124	0.260189092945001
GO:0140297	DNA-binding transcription factor binding	13/289	488/18639	0.0266393442622951	1.71809943842532	0.041646748633035	0.260189092945001
GO:0005080	protein kinase C binding	3/289	52/18639	0.0576923076923077	3.72085440511046	0.0467274395613795	0.287288734111192
GO:0019001	guanyl nucleotide binding	11/289	400/18639	0.0275	1.77360726643599	0.0482426161897406	0.287288734111192
GO:0032561	guanyl ribonucleotide binding	11/289	400/18639	0.0275	1.77360726643599	0.0482426161897406	0.287288734111192
GO:0042171	lysophosphatidic acid acyltransferase activity	2/289	23/18639	0.0869565217391304	5.6082443207462	0.0489418111192893	0.287288734111192
GO:0071617	lysophospholipid acyltransferase activity	2/289	23/18639	0.0869565217391304	5.6082443207462	0.0489418111192893	0.287288734111192
GO:0140296	general transcription initiation factor binding	3/289	53/18639	0.0566037735849057	3.65064960501404	0.0489829271375907	0.287288734111192
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	4/289	89/18639	0.0449438202247191	2.89864313207107	0.049669587674483	0.287288734111192
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	4/289	89/18639	0.0449438202247191	2.89864313207107	0.049669587674483	0.287288734111192
GO:0141003	histone H2AX kinase activity	10/289	354/18639	0.0282485875706215	1.82188727933846	0.0500820297182743	0.287288734111192
GO:0015485	cholesterol binding	3/289	54/18639	0.0555555555555556	3.58304498269896	0.0512907968604976	0.289430822940575
GO:0140793	histone H2AXY142 phosphatase activity	4/289	90/18639	0.0444444444444444	2.86643598615917	0.0513728243571226	0.289430822940575
GO:0001091	RNA polymerase II general transcription initiation factor binding	2/289	24/18639	0.0833333333333333	5.37456747404844	0.0528577273128123	0.292572157319163
GO:0060229	lipase activator activity	2/289	24/18639	0.0833333333333333	5.37456747404844	0.0528577273128123	0.292572157319163
GO:0140313	molecular sequestering activity	3/289	55/18639	0.0545454545454545	3.51789871028625	0.053650549592448	0.294378232981171
GO:0106310	protein serine kinase activity	10/289	361/18639	0.0277008310249307	1.78655982516846	0.0557102336652618	0.299098740086647
GO:0030170	pyridoxal phosphate binding	3/289	56/18639	0.0535714285714286	3.45507909045971	0.056061663587757	0.299098740086647
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	2/289	25/18639	0.08	5.15958477508651	0.0568809014427855	0.299098740086647
GO:0017025	TBP-class protein binding	2/289	25/18639	0.08	5.15958477508651	0.0568809014427855	0.299098740086647
GO:0120020	cholesterol transfer activity	2/289	25/18639	0.08	5.15958477508651	0.0568809014427855	0.299098740086647
GO:0070279	vitamin B6 binding	3/289	57/18639	0.0526315789473684	3.39446366782007	0.0585235956953996	0.305193296560307
GO:0140789	histone phosphatase activity	5/289	136/18639	0.0367647058823529	2.37113270913902	0.0608234528679741	0.308108630182454
GO:0004529	DNA exonuclease activity	2/289	26/18639	0.0769230769230769	4.96113920681395	0.0610070918706902	0.308108630182454
GO:0034237	protein kinase A regulatory subunit binding	2/289	26/18639	0.0769230769230769	4.96113920681395	0.0610070918706902	0.308108630182454
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	3/289	58/18639	0.0517241379310345	3.335938432168	0.0610357825242579	0.308108630182454
GO:0016791	phosphatase activity	8/289	273/18639	0.0293040293040293	1.88995779307198	0.0632894906904073	0.311829501192875
GO:0070063	RNA polymerase binding	3/289	59/18639	0.0508474576271186	3.27939710280922	0.0635976415718736	0.311829501192875
GO:0070888	E-box binding	3/289	59/18639	0.0508474576271186	3.27939710280922	0.0635976415718736	0.311829501192875
GO:0004364	glutathione transferase activity	2/289	27/18639	0.0740740740740741	4.77739331026528	0.0652321618977172	0.311829501192875
GO:0005385	zinc ion transmembrane transporter activity	2/289	27/18639	0.0740740740740741	4.77739331026528	0.0652321618977172	0.311829501192875
GO:0008320	protein transmembrane transporter activity	2/289	27/18639	0.0740740740740741	4.77739331026528	0.0652321618977172	0.311829501192875
GO:0023026	MHC class II protein complex binding	2/289	27/18639	0.0740740740740741	4.77739331026528	0.0652321618977172	0.311829501192875
GO:0004725	protein tyrosine phosphatase activity	4/289	98/18639	0.0408163265306122	2.63244121177883	0.0661302523035182	0.313745783485113
GO:0005085	guanyl-nucleotide exchange factor activity	7/289	230/18639	0.0304347826086957	1.96288551226117	0.0677609518523639	0.319083288200311
GO:0016836	hydro-lyase activity	3/289	61/18639	0.0491803278688525	3.17187588632367	0.0688679572813188	0.321893933663053
GO:0019789	SUMO transferase activity	2/289	28/18639	0.0714285714285714	4.60677212061295	0.069552077548956	0.322701183333759
GO:0019787	ubiquitin-like protein transferase activity	12/289	479/18639	0.0250521920668058	1.61573635963043	0.0708535782293701	0.32634020337761
GO:0008238	exopeptidase activity	4/289	102/18639	0.0392156862745098	2.52920822308162	0.0742502716005628	0.339506676666342
GO:0019902	phosphatase binding	6/289	190/18639	0.0315789473684211	2.03667820069204	0.0759861860259337	0.34494448476521
GO:0015631	tubulin binding	10/289	385/18639	0.025974025974026	1.67518986204107	0.0780980907401582	0.35112603825494
GO:0015215	nucleotide transmembrane transporter activity	2/289	30/18639	0.0666666666666667	4.29965397923875	0.0784608104499945	0.35112603825494
GO:0120013	lipid transfer activity	3/289	65/18639	0.0461538461538462	2.97668352408837	0.0799771525965865	0.355391431608775
GO:0019209	kinase activator activity	5/289	148/18639	0.0337837837837838	2.17887870569531	0.0807904953392665	0.356495122790749
GO:0016411	acylglycerol O-acyltransferase activity	2/289	31/18639	0.0645161290322581	4.16095546377944	0.0830420540258709	0.363885667293921
GO:0003712	transcription coregulator activity	12/289	495/18639	0.0242424242424242	1.563510537905	0.0854339524410052	0.368937251924327
GO:0016755	aminoacyltransferase activity	12/289	496/18639	0.0241935483870968	1.56035829891729	0.0864032014504819	0.368937251924327
GO:0005496	steroid binding	4/289	108/18639	0.037037037037037	2.38869665513264	0.087326417512908	0.368937251924327
GO:0022884	macromolecule transmembrane transporter activity	2/289	32/18639	0.0625	4.03092560553633	0.0877029917411236	0.368937251924327
GO:0051059	NF-kappaB binding	2/289	32/18639	0.0625	4.03092560553633	0.0877029917411236	0.368937251924327
GO:0140142	nucleocytoplasmic carrier activity	2/289	32/18639	0.0625	4.03092560553633	0.0877029917411236	0.368937251924327
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	3/289	68/18639	0.0441176470588235	2.84535925096682	0.0887853987896571	0.371017130041547
GO:0004842	ubiquitin-protein transferase activity	11/289	449/18639	0.0244988864142539	1.58005101686948	0.0915885043224026	0.378349772499479
GO:0016829	lyase activity	6/289	200/18639	0.03	1.93484429065744	0.091739326770872	0.378349772499479
GO:0140104	molecular carrier activity	7/289	249/18639	0.0281124497991968	1.81310709967899	0.0936597221654976	0.383761588872915
GO:0097110	scaffold protein binding	3/289	70/18639	0.0428571428571429	2.76406327236777	0.0948738463637356	0.386228368100111
GO:0003714	transcription corepressor activity	6/289	204/18639	0.0294117647058824	1.89690616731122	0.0985003348051147	0.398421226038637
GO:0005154	epidermal growth factor receptor binding	2/289	35/18639	0.0571428571428571	3.68541769649036	0.102128898211952	0.407869207416085
GO:0061631	ubiquitin conjugating enzyme activity	2/289	35/18639	0.0571428571428571	3.68541769649036	0.102128898211952	0.407869207416085
GO:0000993	RNA polymerase II complex binding	2/289	36/18639	0.0555555555555556	3.58304498269896	0.107073984824231	0.413779888164817
GO:0005484	SNAP receptor activity	2/289	36/18639	0.0555555555555556	3.58304498269896	0.107073984824231	0.413779888164817
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	2/289	36/18639	0.0555555555555556	3.58304498269896	0.107073984824231	0.413779888164817
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	2/289	36/18639	0.0555555555555556	3.58304498269896	0.107073984824231	0.413779888164817
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	2/289	36/18639	0.0555555555555556	3.58304498269896	0.107073984824231	0.413779888164817
GO:0003684	damaged DNA binding	3/289	74/18639	0.0405405405405405	2.61465444683438	0.107543425767084	0.413779888164817
GO:0022853	active monoatomic ion transmembrane transporter activity	4/289	118/18639	0.0338983050847458	2.18626473520615	0.11138927211144	0.425979580014054
GO:0023023	MHC protein complex binding	2/289	37/18639	0.0540540540540541	3.4862059291125	0.112081888971884	0.426046216513609
GO:0015399	primary active transmembrane transporter activity	5/289	166/18639	0.0301204819277108	1.94261474965606	0.116445695111492	0.436871688051984
GO:0042162	telomeric DNA binding	2/289	38/18639	0.0526315789473684	3.39446366782007	0.117149491149037	0.436871688051984
GO:0003697	single-stranded DNA binding	4/289	121/18639	0.0330578512396694	2.13205982441591	0.119128629342781	0.436871688051984
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/289	39/18639	0.0512820512820513	3.30742613787596	0.122273752876248	0.436871688051984
GO:0016835	carbon-oxygen lyase activity	3/289	79/18639	0.0379746835443038	2.44916998817397	0.124241797297475	0.436871688051984
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/289	40/18639	0.05	3.22474048442907	0.127451714952374	0.436871688051984
GO:0061791	GTPase motor activity	2/289	40/18639	0.05	3.22474048442907	0.127451714952374	0.436871688051984
GO:1990606	membrane scission GTPase motor activity	2/289	40/18639	0.05	3.22474048442907	0.127451714952374	0.436871688051984
GO:0033192	calmodulin-dependent protein phosphatase activity	3/289	81/18639	0.037037037037037	2.38869665513264	0.131169353800863	0.436871688051984
GO:0140791	histone H2AXS140 phosphatase activity	3/289	81/18639	0.037037037037037	2.38869665513264	0.131169353800863	0.436871688051984
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	3/289	81/18639	0.037037037037037	2.38869665513264	0.131169353800863	0.436871688051984
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	3/289	81/18639	0.037037037037037	2.38869665513264	0.131169353800863	0.436871688051984
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	3/289	81/18639	0.037037037037037	2.38869665513264	0.131169353800863	0.436871688051984
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	3/289	81/18639	0.037037037037037	2.38869665513264	0.131169353800863	0.436871688051984
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	3/289	81/18639	0.037037037037037	2.38869665513264	0.131169353800863	0.436871688051984
GO:1990439	MAP kinase serine/threonine phosphatase activity	3/289	81/18639	0.037037037037037	2.38869665513264	0.131169353800863	0.436871688051984
GO:0001530	lipopolysaccharide binding	2/289	41/18639	0.0487804878048781	3.14608827749177	0.132680495740866	0.436871688051984
GO:0016877	ligase activity, forming carbon-sulfur bonds	2/289	41/18639	0.0487804878048781	3.14608827749177	0.132680495740866	0.436871688051984
GO:0140318	protein transporter activity	2/289	41/18639	0.0487804878048781	3.14608827749177	0.132680495740866	0.436871688051984
GO:0033549	MAP kinase phosphatase activity	3/289	82/18639	0.0365853658536585	2.35956620811883	0.134683202502137	0.436871688051984
GO:0004674	protein serine/threonine kinase activity	10/289	433/18639	0.023094688221709	1.48948752167624	0.137522514076548	0.436871688051984
GO:0016859	cis-trans isomerase activity	2/289	42/18639	0.0476190476190476	3.07118141374197	0.137957289489845	0.436871688051984
GO:0048487	beta-tubulin binding	2/289	42/18639	0.0476190476190476	3.07118141374197	0.137957289489845	0.436871688051984
GO:0004527	exonuclease activity	3/289	84/18639	0.0357142857142857	2.30338606030648	0.141807127809917	0.436871688051984
GO:0004860	protein kinase inhibitor activity	3/289	84/18639	0.0357142857142857	2.30338606030648	0.141807127809917	0.436871688051984
GO:0017018	myosin phosphatase activity	3/289	84/18639	0.0357142857142857	2.30338606030648	0.141807127809917	0.436871688051984
GO:0051117	ATPase binding	3/289	84/18639	0.0357142857142857	2.30338606030648	0.141807127809917	0.436871688051984
GO:0004955	prostaglandin receptor activity	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0016783	sulfurtransferase activity	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0032356	oxidized DNA binding	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0043295	glutathione binding	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0047429	nucleoside triphosphate diphosphatase activity	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0050815	phosphoserine residue binding	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0051864	histone H3K36 demethylase activity	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0051880	G-quadruplex DNA binding	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0070513	death domain binding	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0098505	G-rich strand telomeric DNA binding	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0099122	RNA polymerase II C-terminal domain binding	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:1990763	arrestin family protein binding	1/289	10/18639	0.1	6.44948096885813	0.144700765139247	0.436871688051984
GO:0046915	transition metal ion transmembrane transporter activity	2/289	45/18639	0.0444444444444444	2.86643598615917	0.154048794896195	0.441625923694945
GO:0140303	intramembrane lipid transporter activity	2/289	45/18639	0.0444444444444444	2.86643598615917	0.154048794896195	0.441625923694945
GO:0051087	protein-folding chaperone binding	4/289	134/18639	0.0298507462686567	1.92521819965914	0.155165819108892	0.441625923694945
GO:0016651	oxidoreductase activity, acting on NAD(P)H	3/289	88/18639	0.0340909090909091	2.19868669392891	0.156417976132681	0.441625923694945
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/289	11/18639	0.0909090909090909	5.86316451714376	0.157969404297267	0.441625923694945
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/289	11/18639	0.0909090909090909	5.86316451714376	0.157969404297267	0.441625923694945
GO:0004954	prostanoid receptor activity	1/289	11/18639	0.0909090909090909	5.86316451714376	0.157969404297267	0.441625923694945
GO:0005225	volume-sensitive anion channel activity	1/289	11/18639	0.0909090909090909	5.86316451714376	0.157969404297267	0.441625923694945
GO:0008046	axon guidance receptor activity	1/289	11/18639	0.0909090909090909	5.86316451714376	0.157969404297267	0.441625923694945
GO:0015217	ADP transmembrane transporter activity	1/289	11/18639	0.0909090909090909	5.86316451714376	0.157969404297267	0.441625923694945
GO:0019107	myristoyltransferase activity	1/289	11/18639	0.0909090909090909	5.86316451714376	0.157969404297267	0.441625923694945
GO:0032050	clathrin heavy chain binding	1/289	11/18639	0.0909090909090909	5.86316451714376	0.157969404297267	0.441625923694945
GO:0032404	mismatch repair complex binding	1/289	11/18639	0.0909090909090909	5.86316451714376	0.157969404297267	0.441625923694945
GO:0047676	arachidonate-CoA ligase activity	1/289	11/18639	0.0909090909090909	5.86316451714376	0.157969404297267	0.441625923694945
GO:0140031	phosphorylation-dependent protein binding	1/289	11/18639	0.0909090909090909	5.86316451714376	0.157969404297267	0.441625923694945
GO:1900750	oligopeptide binding	1/289	11/18639	0.0909090909090909	5.86316451714376	0.157969404297267	0.441625923694945
GO:0030291	protein serine/threonine kinase inhibitor activity	2/289	46/18639	0.0434782608695652	2.8041221603731	0.159491043704214	0.441625923694945
GO:0015078	proton transmembrane transporter activity	5/289	185/18639	0.027027027027027	1.74310296455625	0.160792178235003	0.441625923694945
GO:0002020	protease binding	4/289	136/18639	0.0294117647058824	1.89690616731122	0.161040523652833	0.441625923694945
GO:0019210	kinase inhibitor activity	3/289	90/18639	0.0333333333333333	2.14982698961938	0.163892409979488	0.441625923694945
GO:0140597	protein carrier chaperone	5/289	188/18639	0.0265957446808511	1.71528749171759	0.168350589448039	0.441625923694945
GO:0030295	protein kinase activator activity	4/289	139/18639	0.0287769784172662	1.85596574643399	0.170002140825204	0.441625923694945
GO:0003995	acyl-CoA dehydrogenase activity	1/289	12/18639	0.0833333333333333	5.37456747404844	0.171032902373178	0.441625923694945
GO:0004032	aldose reductase (NADPH) activity	1/289	12/18639	0.0833333333333333	5.37456747404844	0.171032902373178	0.441625923694945
GO:0005049	nuclear export signal receptor activity	1/289	12/18639	0.0833333333333333	5.37456747404844	0.171032902373178	0.441625923694945
GO:0008179	adenylate cyclase binding	1/289	12/18639	0.0833333333333333	5.37456747404844	0.171032902373178	0.441625923694945
GO:0008504	monoamine transmembrane transporter activity	1/289	12/18639	0.0833333333333333	5.37456747404844	0.171032902373178	0.441625923694945
GO:0035197	siRNA binding	1/289	12/18639	0.0833333333333333	5.37456747404844	0.171032902373178	0.441625923694945
GO:0035259	nuclear glucocorticoid receptor binding	1/289	12/18639	0.0833333333333333	5.37456747404844	0.171032902373178	0.441625923694945
GO:0042301	phosphate ion binding	1/289	12/18639	0.0833333333333333	5.37456747404844	0.171032902373178	0.441625923694945
GO:0043047	single-stranded telomeric DNA binding	1/289	12/18639	0.0833333333333333	5.37456747404844	0.171032902373178	0.441625923694945
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/289	12/18639	0.0833333333333333	5.37456747404844	0.171032902373178	0.441625923694945
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/289	12/18639	0.0833333333333333	5.37456747404844	0.171032902373178	0.441625923694945
GO:0097371	MDM2/MDM4 family protein binding	1/289	12/18639	0.0833333333333333	5.37456747404844	0.171032902373178	0.441625923694945
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/289	12/18639	0.0833333333333333	5.37456747404844	0.171032902373178	0.441625923694945
GO:0043178	alcohol binding	3/289	92/18639	0.0326086956521739	2.10309162027983	0.171471238201682	0.441625923694945
GO:0051219	phosphoprotein binding	3/289	93/18639	0.032258064516129	2.08047773188972	0.175297874298325	0.449646173505054
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	8/289	349/18639	0.0229226361031519	1.47839105303338	0.176358502548622	0.450535283838788
GO:0015605	organophosphate ester transmembrane transporter activity	2/289	50/18639	0.04	2.57979238754325	0.181587183130358	0.45684007519922
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/289	13/18639	0.0769230769230769	4.96113920681395	0.183894420127737	0.45684007519922
GO:0008035	high-density lipoprotein particle binding	1/289	13/18639	0.0769230769230769	4.96113920681395	0.183894420127737	0.45684007519922
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/289	13/18639	0.0769230769230769	4.96113920681395	0.183894420127737	0.45684007519922
GO:0045159	myosin II binding	1/289	13/18639	0.0769230769230769	4.96113920681395	0.183894420127737	0.45684007519922
GO:0097157	pre-mRNA intronic binding	1/289	13/18639	0.0769230769230769	4.96113920681395	0.183894420127737	0.45684007519922
GO:0140666	annealing activity	1/289	13/18639	0.0769230769230769	4.96113920681395	0.183894420127737	0.45684007519922
GO:0019903	protein phosphatase binding	4/289	144/18639	0.0277777777777778	1.79152249134948	0.185312966065401	0.458558751322619
GO:0005347	ATP transmembrane transporter activity	1/289	14/18639	0.0714285714285714	4.60677212061295	0.196557069788592	0.468028343534345
GO:0008191	metalloendopeptidase inhibitor activity	1/289	14/18639	0.0714285714285714	4.60677212061295	0.196557069788592	0.468028343534345
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/289	14/18639	0.0714285714285714	4.60677212061295	0.196557069788592	0.468028343534345
GO:0019992	diacylglycerol binding	1/289	14/18639	0.0714285714285714	4.60677212061295	0.196557069788592	0.468028343534345
GO:0032454	histone H3K9 demethylase activity	1/289	14/18639	0.0714285714285714	4.60677212061295	0.196557069788592	0.468028343534345
GO:0044548	S100 protein binding	1/289	14/18639	0.0714285714285714	4.60677212061295	0.196557069788592	0.468028343534345
GO:0046030	inositol trisphosphate phosphatase activity	1/289	14/18639	0.0714285714285714	4.60677212061295	0.196557069788592	0.468028343534345
GO:0061665	SUMO ligase activity	1/289	14/18639	0.0714285714285714	4.60677212061295	0.196557069788592	0.468028343534345
GO:0070742	C2H2 zinc finger domain binding	1/289	14/18639	0.0714285714285714	4.60677212061295	0.196557069788592	0.468028343534345
GO:0098847	sequence-specific single stranded DNA binding	1/289	14/18639	0.0714285714285714	4.60677212061295	0.196557069788592	0.468028343534345
GO:0016251	RNA polymerase II general transcription initiation factor activity	2/289	53/18639	0.0377358490566038	2.43376640334269	0.198439605430088	0.468971501971482
GO:0051018	protein kinase A binding	2/289	53/18639	0.0377358490566038	2.43376640334269	0.198439605430088	0.468971501971482
GO:0043130	ubiquitin binding	3/289	100/18639	0.03	1.93484429065744	0.202708237165324	0.471050324519103
GO:0042578	phosphoric ester hydrolase activity	8/289	363/18639	0.0220385674931129	1.42137321627727	0.203498707297261	0.471050324519103
GO:0017069	snRNA binding	2/289	54/18639	0.037037037037037	2.38869665513264	0.204099174990457	0.471050324519103
GO:0000774	adenyl-nucleotide exchange factor activity	1/289	15/18639	0.0666666666666667	4.29965397923875	0.209023915792946	0.471050324519103
GO:0004467	long-chain fatty acid-CoA ligase activity	1/289	15/18639	0.0666666666666667	4.29965397923875	0.209023915792946	0.471050324519103
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/289	15/18639	0.0666666666666667	4.29965397923875	0.209023915792946	0.471050324519103
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/289	15/18639	0.0666666666666667	4.29965397923875	0.209023915792946	0.471050324519103
GO:0004953	icosanoid receptor activity	1/289	15/18639	0.0666666666666667	4.29965397923875	0.209023915792946	0.471050324519103
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/289	15/18639	0.0666666666666667	4.29965397923875	0.209023915792946	0.471050324519103
GO:0016846	carbon-sulfur lyase activity	1/289	15/18639	0.0666666666666667	4.29965397923875	0.209023915792946	0.471050324519103
GO:0031005	filamin binding	1/289	15/18639	0.0666666666666667	4.29965397923875	0.209023915792946	0.471050324519103
GO:0047372	monoacylglycerol lipase activity	1/289	15/18639	0.0666666666666667	4.29965397923875	0.209023915792946	0.471050324519103
GO:0140776	protein-containing complex destabilizing activity	1/289	15/18639	0.0666666666666667	4.29965397923875	0.209023915792946	0.471050324519103
GO:0008374	O-acyltransferase activity	2/289	55/18639	0.0363636363636364	2.3452658068575	0.20977648160925	0.471063914218637
GO:0051020	GTPase binding	7/289	315/18639	0.0222222222222222	1.43321799307958	0.218434372678697	0.479258813651341
GO:0004386	helicase activity	4/289	155/18639	0.0258064516129032	1.66438218551178	0.220442009955054	0.479258813651341
GO:0004601	peroxidase activity	2/289	57/18639	0.0350877192982456	2.26297577854671	0.22117675128371	0.479258813651341
GO:0015932	nucleobase-containing compound transmembrane transporter activity	2/289	57/18639	0.0350877192982456	2.26297577854671	0.22117675128371	0.479258813651341
GO:0003688	DNA replication origin binding	1/289	16/18639	0.0625	4.03092560553633	0.221297975518882	0.479258813651341
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	1/289	16/18639	0.0625	4.03092560553633	0.221297975518882	0.479258813651341
GO:0005149	interleukin-1 receptor binding	1/289	16/18639	0.0625	4.03092560553633	0.221297975518882	0.479258813651341
GO:0005521	lamin binding	1/289	16/18639	0.0625	4.03092560553633	0.221297975518882	0.479258813651341
GO:0015378	sodium:chloride symporter activity	1/289	16/18639	0.0625	4.03092560553633	0.221297975518882	0.479258813651341
GO:0140328	floppase activity	1/289	16/18639	0.0625	4.03092560553633	0.221297975518882	0.479258813651341
GO:0061659	ubiquitin-like protein ligase activity	8/289	372/18639	0.021505376344086	1.38698515459315	0.221780623749907	0.479258813651341
GO:0008094	ATP-dependent activity, acting on DNA	5/289	210/18639	0.0238095238095238	1.53559070687098	0.227600638220394	0.490157005860303
GO:0019888	protein phosphatase regulator activity	3/289	107/18639	0.0280373831775701	1.80826569220321	0.231029097041341	0.492522343891292
GO:0004879	nuclear receptor activity	2/289	59/18639	0.0338983050847458	2.18626473520615	0.232625841071098	0.492522343891292
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	2/289	59/18639	0.0338983050847458	2.18626473520615	0.232625841071098	0.492522343891292
GO:0045309	protein phosphorylated amino acid binding	2/289	59/18639	0.0338983050847458	2.18626473520615	0.232625841071098	0.492522343891292
GO:0032977	membrane insertase activity	1/289	17/18639	0.0588235294117647	3.79381233462243	0.233382220005541	0.492522343891292
GO:1990226	histone methyltransferase binding	1/289	17/18639	0.0588235294117647	3.79381233462243	0.233382220005541	0.492522343891292
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/289	60/18639	0.0333333333333333	2.14982698961938	0.238364367579838	0.494477353392712
GO:0098531	ligand-modulated transcription factor activity	2/289	60/18639	0.0333333333333333	2.14982698961938	0.238364367579838	0.494477353392712
GO:0000400	four-way junction DNA binding	1/289	18/18639	0.0555555555555556	3.58304498269896	0.245279574662312	0.494477353392712
GO:0008308	voltage-gated monoatomic anion channel activity	1/289	18/18639	0.0555555555555556	3.58304498269896	0.245279574662312	0.494477353392712
GO:0008525	phosphatidylcholine transporter activity	1/289	18/18639	0.0555555555555556	3.58304498269896	0.245279574662312	0.494477353392712
GO:0015373	monoatomic anion:sodium symporter activity	1/289	18/18639	0.0555555555555556	3.58304498269896	0.245279574662312	0.494477353392712
GO:0017128	phospholipid scramblase activity	1/289	18/18639	0.0555555555555556	3.58304498269896	0.245279574662312	0.494477353392712
GO:0031690	adrenergic receptor binding	1/289	18/18639	0.0555555555555556	3.58304498269896	0.245279574662312	0.494477353392712
GO:0034185	apolipoprotein binding	1/289	18/18639	0.0555555555555556	3.58304498269896	0.245279574662312	0.494477353392712
GO:0050811	GABA receptor binding	1/289	18/18639	0.0555555555555556	3.58304498269896	0.245279574662312	0.494477353392712
GO:0070064	proline-rich region binding	1/289	18/18639	0.0555555555555556	3.58304498269896	0.245279574662312	0.494477353392712
GO:0070628	proteasome binding	1/289	18/18639	0.0555555555555556	3.58304498269896	0.245279574662312	0.494477353392712
GO:0098641	cadherin binding involved in cell-cell adhesion	1/289	18/18639	0.0555555555555556	3.58304498269896	0.245279574662312	0.494477353392712
GO:1990381	ubiquitin-specific protease binding	1/289	18/18639	0.0555555555555556	3.58304498269896	0.245279574662312	0.494477353392712
GO:0140713	histone chaperone activity	4/289	164/18639	0.024390243902439	1.57304413874589	0.250386345502073	0.503164917235058
GO:0005229	intracellularly calcium-gated chloride channel activity	1/289	19/18639	0.0526315789473684	3.39446366782007	0.256992919967215	0.511553730281743
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/289	19/18639	0.0526315789473684	3.39446366782007	0.256992919967215	0.511553730281743
GO:0141147	intracellularly calcium-gated channel activity	1/289	19/18639	0.0526315789473684	3.39446366782007	0.256992919967215	0.511553730281743
GO:0016874	ligase activity	4/289	167/18639	0.0239520958083832	1.54478586080434	0.260557977077894	0.513452524695651
GO:0004536	DNA nuclease activity	2/289	64/18639	0.03125	2.01546280276817	0.261373914398992	0.513452524695651
GO:0140097	catalytic activity, acting on DNA	7/289	336/18639	0.0208333333333333	1.34364186851211	0.267009113931964	0.513452524695651
GO:0019843	rRNA binding	2/289	65/18639	0.0307692307692308	1.98445568272558	0.267132541757799	0.513452524695651
GO:0009055	electron transfer activity	3/289	116/18639	0.0258620689655172	1.667969216084	0.268389725338195	0.513452524695651
GO:0001614	purinergic nucleotide receptor activity	1/289	20/18639	0.05	3.22474048442907	0.268525092154619	0.513452524695651
GO:0016004	phospholipase activator activity	1/289	20/18639	0.05	3.22474048442907	0.268525092154619	0.513452524695651
GO:0016502	nucleotide receptor activity	1/289	20/18639	0.05	3.22474048442907	0.268525092154619	0.513452524695651
GO:0030627	pre-mRNA 5'-splice site binding	1/289	20/18639	0.05	3.22474048442907	0.268525092154619	0.513452524695651
GO:0030742	GTP-dependent protein binding	1/289	20/18639	0.05	3.22474048442907	0.268525092154619	0.513452524695651
GO:0042288	MHC class I protein binding	1/289	20/18639	0.05	3.22474048442907	0.268525092154619	0.513452524695651
GO:0052745	inositol phosphate phosphatase activity	1/289	20/18639	0.05	3.22474048442907	0.268525092154619	0.513452524695651
GO:0061608	nuclear import signal receptor activity	1/289	20/18639	0.05	3.22474048442907	0.268525092154619	0.513452524695651
GO:0019208	phosphatase regulator activity	3/289	117/18639	0.0256410256410256	1.65371306893798	0.272587845680092	0.519646316085009
GO:0031267	small GTPase binding	6/289	283/18639	0.0212014134275618	1.36738112413953	0.276424341185806	0.524734272465669
GO:0016500	protein-hormone receptor activity	2/289	67/18639	0.0298507462686567	1.92521819965914	0.278647251663174	0.524734272465669
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/289	21/18639	0.0476190476190476	3.07118141374197	0.279878883892485	0.524734272465669
GO:0072542	protein phosphatase activator activity	1/289	21/18639	0.0476190476190476	3.07118141374197	0.279878883892485	0.524734272465669
GO:1904047	S-adenosyl-L-methionine binding	1/289	21/18639	0.0476190476190476	3.07118141374197	0.279878883892485	0.524734272465669
GO:0140030	modification-dependent protein binding	4/289	173/18639	0.023121387283237	1.49120947256835	0.281128791632216	0.524734272465669
GO:0005548	phospholipid transporter activity	2/289	68/18639	0.0294117647058824	1.89690616731122	0.284400641144189	0.524734272465669
GO:0030145	manganese ion binding	2/289	68/18639	0.0294117647058824	1.89690616731122	0.284400641144189	0.524734272465669
GO:0140223	general transcription initiation factor activity	2/289	68/18639	0.0294117647058824	1.89690616731122	0.284400641144189	0.524734272465669
GO:0032182	ubiquitin-like protein binding	3/289	120/18639	0.025	1.61237024221453	0.285222123734841	0.524734272465669
GO:0008970	phospholipase A1 activity	1/289	22/18639	0.0454545454545455	2.93158225857188	0.291057044949262	0.524734272465669
GO:0015377	chloride:monoatomic cation symporter activity	1/289	22/18639	0.0454545454545455	2.93158225857188	0.291057044949262	0.524734272465669
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/289	22/18639	0.0454545454545455	2.93158225857188	0.291057044949262	0.524734272465669
GO:0016881	acid-amino acid ligase activity	1/289	22/18639	0.0454545454545455	2.93158225857188	0.291057044949262	0.524734272465669
GO:0034062	5'-3' RNA polymerase activity	1/289	22/18639	0.0454545454545455	2.93158225857188	0.291057044949262	0.524734272465669
GO:0050321	tau-protein kinase activity	1/289	22/18639	0.0454545454545455	2.93158225857188	0.291057044949262	0.524734272465669
GO:0061133	endopeptidase activator activity	1/289	22/18639	0.0454545454545455	2.93158225857188	0.291057044949262	0.524734272465669
GO:0097747	RNA polymerase activity	1/289	22/18639	0.0454545454545455	2.93158225857188	0.291057044949262	0.524734272465669
GO:0140517	protein-RNA adaptor activity	1/289	22/18639	0.0454545454545455	2.93158225857188	0.291057044949262	0.524734272465669
GO:0005319	lipid transporter activity	4/289	178/18639	0.0224719101123595	1.44932156603554	0.298458408163784	0.536544887610677
GO:0000295	adenine nucleotide transmembrane transporter activity	1/289	23/18639	0.0434782608695652	2.8041221603731	0.302062282850624	0.536905071771109
GO:0004602	glutathione peroxidase activity	1/289	23/18639	0.0434782608695652	2.8041221603731	0.302062282850624	0.536905071771109
GO:0031681	G-protein beta-subunit binding	1/289	23/18639	0.0434782608695652	2.8041221603731	0.302062282850624	0.536905071771109
GO:0043274	phospholipase binding	1/289	23/18639	0.0434782608695652	2.8041221603731	0.302062282850624	0.536905071771109
GO:0061630	ubiquitin protein ligase activity	7/289	353/18639	0.0198300283286119	1.278933903173	0.308297864120129	0.54156305076427
GO:0005315	phosphate transmembrane transporter activity	1/289	24/18639	0.0416666666666667	2.68728373702422	0.312897263526181	0.54156305076427
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/289	24/18639	0.0416666666666667	2.68728373702422	0.312897263526181	0.54156305076427
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/289	24/18639	0.0416666666666667	2.68728373702422	0.312897263526181	0.54156305076427
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/289	24/18639	0.0416666666666667	2.68728373702422	0.312897263526181	0.54156305076427
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/289	24/18639	0.0416666666666667	2.68728373702422	0.312897263526181	0.54156305076427
GO:0048027	mRNA 5'-UTR binding	1/289	24/18639	0.0416666666666667	2.68728373702422	0.312897263526181	0.54156305076427
GO:0031491	nucleosome binding	2/289	74/18639	0.027027027027027	1.74310296455625	0.318787037837836	0.54156305076427
GO:0035064	methylated histone binding	2/289	74/18639	0.027027027027027	1.74310296455625	0.318787037837836	0.54156305076427
GO:0031490	chromatin DNA binding	3/289	128/18639	0.0234375	1.51159710207612	0.319102228554498	0.54156305076427
GO:0008237	metallopeptidase activity	4/289	184/18639	0.0217391304347826	1.40206108018655	0.319415773079192	0.54156305076427
GO:0008139	nuclear localization sequence binding	1/289	25/18639	0.04	2.57979238754325	0.323564611946323	0.54156305076427
GO:0008483	transaminase activity	1/289	25/18639	0.04	2.57979238754325	0.323564611946323	0.54156305076427
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/289	25/18639	0.04	2.57979238754325	0.323564611946323	0.54156305076427
GO:0015645	fatty acid ligase activity	1/289	25/18639	0.04	2.57979238754325	0.323564611946323	0.54156305076427
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/289	25/18639	0.04	2.57979238754325	0.323564611946323	0.54156305076427
GO:0017056	structural constituent of nuclear pore	1/289	25/18639	0.04	2.57979238754325	0.323564611946323	0.54156305076427
GO:0019211	phosphatase activator activity	1/289	25/18639	0.04	2.57979238754325	0.323564611946323	0.54156305076427
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/289	25/18639	0.04	2.57979238754325	0.323564611946323	0.54156305076427
GO:0019707	protein-cysteine S-acyltransferase activity	1/289	25/18639	0.04	2.57979238754325	0.323564611946323	0.54156305076427
GO:0047617	fatty acyl-CoA hydrolase activity	1/289	25/18639	0.04	2.57979238754325	0.323564611946323	0.54156305076427
GO:0120515	fatty acid-CoA ligase activity	1/289	25/18639	0.04	2.57979238754325	0.323564611946323	0.54156305076427
GO:0140034	methylation-dependent protein binding	2/289	76/18639	0.0263157894736842	1.69723183391003	0.330170808456207	0.544693079960823
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	1/289	26/18639	0.0384615384615385	2.48056960340697	0.334066912749348	0.544693079960823
GO:0008157	protein phosphatase 1 binding	1/289	26/18639	0.0384615384615385	2.48056960340697	0.334066912749348	0.544693079960823
GO:0008198	ferrous iron binding	1/289	26/18639	0.0384615384615385	2.48056960340697	0.334066912749348	0.544693079960823
GO:0015216	purine nucleotide transmembrane transporter activity	1/289	26/18639	0.0384615384615385	2.48056960340697	0.334066912749348	0.544693079960823
GO:0016289	acyl-CoA hydrolase activity	1/289	26/18639	0.0384615384615385	2.48056960340697	0.334066912749348	0.544693079960823
GO:0019865	immunoglobulin binding	1/289	26/18639	0.0384615384615385	2.48056960340697	0.334066912749348	0.544693079960823
GO:0052742	phosphatidylinositol kinase activity	1/289	26/18639	0.0384615384615385	2.48056960340697	0.334066912749348	0.544693079960823
GO:0070006	metalloaminopeptidase activity	1/289	26/18639	0.0384615384615385	2.48056960340697	0.334066912749348	0.544693079960823
GO:0097602	cullin family protein binding	1/289	26/18639	0.0384615384615385	2.48056960340697	0.334066912749348	0.544693079960823
GO:0003724	RNA helicase activity	2/289	77/18639	0.025974025974026	1.67518986204107	0.335843284223179	0.546178124600067
GO:0016405	CoA-ligase activity	1/289	27/18639	0.037037037037037	2.38869665513264	0.344406710859026	0.557232396287296
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	1/289	27/18639	0.037037037037037	2.38869665513264	0.344406710859026	0.557232396287296
GO:0008186	ATP-dependent activity, acting on RNA	2/289	79/18639	0.0253164556962025	1.63277999211598	0.347144647846578	0.560225761614298
GO:0046982	protein heterodimerization activity	7/289	369/18639	0.018970189701897	1.22347877458013	0.34821218120732	0.56051501617811
GO:0000049	tRNA binding	2/289	80/18639	0.025	1.61237024221453	0.352771725361061	0.565010326087157
GO:0044325	transmembrane transporter binding	3/289	136/18639	0.0220588235294118	1.42267962548341	0.353033225220586	0.565010326087157
GO:0051959	dynein light intermediate chain binding	1/289	28/18639	0.0357142857142857	2.30338606030648	0.354586512092732	0.565010326087157
GO:0141052	histone H3 demethylase activity	1/289	28/18639	0.0357142857142857	2.30338606030648	0.354586512092732	0.565010326087157
GO:0003785	actin monomer binding	1/289	29/18639	0.0344827586206897	2.22395895477867	0.364608783760305	0.573736016341029
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/289	29/18639	0.0344827586206897	2.22395895477867	0.364608783760305	0.573736016341029
GO:0016417	S-acyltransferase activity	1/289	29/18639	0.0344827586206897	2.22395895477867	0.364608783760305	0.573736016341029
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/289	29/18639	0.0344827586206897	2.22395895477867	0.364608783760305	0.573736016341029
GO:0097472	cyclin-dependent protein kinase activity	1/289	29/18639	0.0344827586206897	2.22395895477867	0.364608783760305	0.573736016341029
GO:0070851	growth factor receptor binding	3/289	139/18639	0.0215827338129496	1.3919743098255	0.365717415291652	0.574048977733911
GO:0001965	G-protein alpha-subunit binding	1/289	30/18639	0.0333333333333333	2.14982698961938	0.374475955253764	0.579152764130209
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/289	30/18639	0.0333333333333333	2.14982698961938	0.374475955253764	0.579152764130209
GO:0016769	transferase activity, transferring nitrogenous groups	1/289	30/18639	0.0333333333333333	2.14982698961938	0.374475955253764	0.579152764130209
GO:0032452	histone demethylase activity	1/289	30/18639	0.0333333333333333	2.14982698961938	0.374475955253764	0.579152764130209
GO:0048019	receptor antagonist activity	1/289	30/18639	0.0333333333333333	2.14982698961938	0.374475955253764	0.579152764130209
GO:0051721	protein phosphatase 2A binding	1/289	30/18639	0.0333333333333333	2.14982698961938	0.374475955253764	0.579152764130209
GO:0020037	heme binding	3/289	142/18639	0.0211267605633803	1.36256640187144	0.378360343567052	0.583729527605892
GO:0005164	tumor necrosis factor receptor binding	1/289	31/18639	0.032258064516129	2.08047773188972	0.384190418628027	0.58556558974465
GO:0005452	solute:inorganic anion antiporter activity	1/289	31/18639	0.032258064516129	2.08047773188972	0.384190418628027	0.58556558974465
GO:0016878	acid-thiol ligase activity	1/289	31/18639	0.032258064516129	2.08047773188972	0.384190418628027	0.58556558974465
GO:0047499	calcium-independent phospholipase A2 activity	1/289	31/18639	0.032258064516129	2.08047773188972	0.384190418628027	0.58556558974465
GO:0140457	protein demethylase activity	1/289	31/18639	0.032258064516129	2.08047773188972	0.384190418628027	0.58556558974465
GO:0016209	antioxidant activity	2/289	86/18639	0.0232558139534884	1.49987929508329	0.386151521313654	0.587136409515459
GO:0030515	snoRNA binding	1/289	32/18639	0.03125	2.01546280276817	0.393754529172766	0.590164151800512
GO:0031369	translation initiation factor binding	1/289	32/18639	0.03125	2.01546280276817	0.393754529172766	0.590164151800512
GO:0043425	bHLH transcription factor binding	1/289	32/18639	0.03125	2.01546280276817	0.393754529172766	0.590164151800512
GO:0047498	calcium-dependent phospholipase A2 activity	1/289	32/18639	0.03125	2.01546280276817	0.393754529172766	0.590164151800512
GO:0071813	lipoprotein particle binding	1/289	32/18639	0.03125	2.01546280276817	0.393754529172766	0.590164151800512
GO:0071814	protein-lipid complex binding	1/289	32/18639	0.03125	2.01546280276817	0.393754529172766	0.590164151800512
GO:0004197	cysteine-type endopeptidase activity	2/289	88/18639	0.0227272727272727	1.46579112928594	0.397114356606876	0.593789476348196
GO:0005516	calmodulin binding	4/289	207/18639	0.0193236714975845	1.24627651572138	0.400211006865979	0.597005071707878
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	5/289	268/18639	0.0186567164179104	1.20326137478696	0.401917858423439	0.59813719024809
GO:0140311	protein sequestering activity	1/289	33/18639	0.0303030303030303	1.95438817238125	0.403170605975532	0.598589770283673
GO:0004518	nuclease activity	4/289	209/18639	0.0191387559808612	1.23435042466184	0.407197180150304	0.602384774338756
GO:0008509	monoatomic anion transmembrane transporter activity	3/289	149/18639	0.0201342281879195	1.29855321520634	0.407635972492312	0.602384774338756
GO:0019842	vitamin binding	3/289	150/18639	0.02	1.28989619377163	0.411786744378677	0.602837722067481
GO:0016831	carboxy-lyase activity	1/289	34/18639	0.0294117647058824	1.89690616731122	0.412440932476289	0.602837722067481
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/289	34/18639	0.0294117647058824	1.89690616731122	0.412440932476289	0.602837722067481
GO:0030332	cyclin binding	1/289	34/18639	0.0294117647058824	1.89690616731122	0.412440932476289	0.602837722067481
GO:0000510	H3-H4 histone complex chaperone activity	3/289	151/18639	0.0198675496688742	1.28135383487248	0.415928533249899	0.602837722067481
GO:0140584	chromatin extrusion motor activity	3/289	151/18639	0.0198675496688742	1.28135383487248	0.415928533249899	0.602837722067481
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	3/289	151/18639	0.0198675496688742	1.28135383487248	0.415928533249899	0.602837722067481
GO:0140849	ATP-dependent H2AZ histone chaperone activity	3/289	151/18639	0.0198675496688742	1.28135383487248	0.415928533249899	0.602837722067481
GO:0052689	carboxylic ester hydrolase activity	2/289	92/18639	0.0217391304347826	1.40206108018655	0.418762595987179	0.602837722067481
GO:0015616	DNA translocase activity	3/289	152/18639	0.0197368421052632	1.27292387543253	0.420060985207176	0.602837722067481
GO:0046906	tetrapyrrole binding	3/289	152/18639	0.0197368421052632	1.27292387543253	0.420060985207176	0.602837722067481
GO:0140674	ATP-dependent histone chaperone activity	3/289	152/18639	0.0197368421052632	1.27292387543253	0.420060985207176	0.602837722067481
GO:0004623	phospholipase A2 activity	1/289	35/18639	0.0285714285714286	1.84270884824518	0.421567757013475	0.602837722067481
GO:0043015	gamma-tubulin binding	1/289	35/18639	0.0285714285714286	1.84270884824518	0.421567757013475	0.602837722067481
GO:0005126	cytokine receptor binding	5/289	275/18639	0.0181818181818182	1.17263290342875	0.423333556465599	0.602837722067481
GO:0051213	dioxygenase activity	2/289	93/18639	0.021505376344086	1.38698515459315	0.42411346899133	0.602837722067481
GO:0061775	cohesin loader activity	3/289	153/18639	0.0196078431372549	1.26460411154081	0.424183753721017	0.602837722067481
GO:0005506	iron ion binding	3/289	154/18639	0.0194805194805195	1.2563923965308	0.42829649957689	0.606426625248343
GO:0004033	aldo-keto reductase (NADPH) activity	1/289	36/18639	0.0277777777777778	1.79152249134948	0.430553293361739	0.606426625248343
GO:0004190	aspartic-type endopeptidase activity	1/289	36/18639	0.0277777777777778	1.79152249134948	0.430553293361739	0.606426625248343
GO:0016409	palmitoyltransferase activity	1/289	36/18639	0.0277777777777778	1.79152249134948	0.430553293361739	0.606426625248343
GO:0001217	DNA-binding transcription repressor activity	5/289	278/18639	0.0179856115107914	1.15997859152125	0.432472338508254	0.607772930063939
GO:0070001	aspartic-type peptidase activity	1/289	37/18639	0.027027027027027	1.74310296455625	0.439399721261457	0.616136053591066
GO:0140658	ATP-dependent chromatin remodeler activity	3/289	158/18639	0.0189873417721519	1.22458499408699	0.444640724991758	0.622102655143679
GO:0042626	ATPase-coupled transmembrane transporter activity	2/289	98/18639	0.0204081632653061	1.31622060588941	0.450475094690897	0.628871205199018
GO:0003689	DNA clamp loader activity	3/289	160/18639	0.01875	1.2092776816609	0.45274441022979	0.630643979812356
GO:0000217	DNA secondary structure binding	1/289	39/18639	0.0256410256410256	1.65371306893798	0.456683803626064	0.634730132352525
GO:0004177	aminopeptidase activity	1/289	40/18639	0.025	1.61237024221453	0.465125652053594	0.642219445176845
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/289	40/18639	0.025	1.61237024221453	0.465125652053594	0.642219445176845
GO:0032451	demethylase activity	1/289	40/18639	0.025	1.61237024221453	0.465125652053594	0.642219445176845
GO:0004857	enzyme inhibitor activity	7/289	416/18639	0.0168269230769231	1.08524920149055	0.466942983887198	0.643321010552013
GO:0015103	inorganic anion transmembrane transporter activity	3/289	165/18639	0.0181818181818182	1.17263290342875	0.472785341614556	0.648023012552389
GO:0001727	lipid kinase activity	1/289	41/18639	0.024390243902439	1.57304413874589	0.473436780961413	0.648023012552389
GO:0042287	MHC protein binding	1/289	41/18639	0.024390243902439	1.57304413874589	0.473436780961413	0.648023012552389
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4/289	229/18639	0.0174672489082969	1.12654689412369	0.475896199092132	0.648911126285641
GO:0005253	monoatomic anion channel activity	2/289	103/18639	0.0194174757281553	1.25232640172003	0.476142395356976	0.648911126285641
GO:0004520	DNA endonuclease activity	1/289	42/18639	0.0238095238095238	1.53559070687098	0.481619207582671	0.653552085988527
GO:0031492	nucleosomal DNA binding	1/289	42/18639	0.0238095238095238	1.53559070687098	0.481619207582671	0.653552085988527
GO:0001664	G protein-coupled receptor binding	5/289	297/18639	0.0168350168350168	1.08577120687847	0.489487378831998	0.660224088330492
GO:0004712	protein serine/threonine/tyrosine kinase activity	1/289	43/18639	0.0232558139534884	1.49987929508329	0.489674918127845	0.660224088330492
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/289	43/18639	0.0232558139534884	1.49987929508329	0.489674918127845	0.660224088330492
GO:0000149	SNARE binding	2/289	106/18639	0.0188679245283019	1.21688320167135	0.491190423397222	0.660855345764707
GO:0005125	cytokine activity	4/289	234/18639	0.0170940170940171	1.10247537929199	0.492623898845788	0.661373787599345
GO:0001046	core promoter sequence-specific DNA binding	1/289	44/18639	0.0227272727272727	1.46579112928594	0.497605868260188	0.663825164634627
GO:0016790	thiolester hydrolase activity	1/289	44/18639	0.0227272727272727	1.46579112928594	0.497605868260188	0.663825164634627
GO:0030547	signaling receptor inhibitor activity	1/289	44/18639	0.0227272727272727	1.46579112928594	0.497605868260188	0.663825164634627
GO:0004715	non-membrane spanning protein tyrosine kinase activity	1/289	45/18639	0.0222222222222222	1.43321799307958	0.505413983563915	0.670381888157675
GO:0008009	chemokine activity	1/289	45/18639	0.0222222222222222	1.43321799307958	0.505413983563915	0.670381888157675
GO:0003735	structural constituent of ribosome	3/289	175/18639	0.0171428571428571	1.10562530894711	0.511822737577311	0.670381888157675
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/289	46/18639	0.0217391304347826	1.40206108018655	0.513101160005242	0.670381888157675
GO:0030276	clathrin binding	1/289	46/18639	0.0217391304347826	1.40206108018655	0.513101160005242	0.670381888157675
GO:0043021	ribonucleoprotein complex binding	3/289	177/18639	0.0169491525423729	1.09313236760307	0.519447722011233	0.670381888157675
GO:0001784	phosphotyrosine residue binding	1/289	47/18639	0.0212765957446809	1.37222999337407	0.520669264386379	0.670381888157675
GO:0043495	protein-membrane adaptor activity	1/289	47/18639	0.0212765957446809	1.37222999337407	0.520669264386379	0.670381888157675
GO:0061749	forked DNA-dependent helicase activity	1/289	47/18639	0.0212765957446809	1.37222999337407	0.520669264386379	0.670381888157675
GO:0099095	ligand-gated monoatomic anion channel activity	1/289	47/18639	0.0212765957446809	1.37222999337407	0.520669264386379	0.670381888157675
GO:0140359	ABC-type transporter activity	1/289	47/18639	0.0212765957446809	1.37222999337407	0.520669264386379	0.670381888157675
GO:1990518	single-stranded 3'-5' DNA helicase activity	1/289	47/18639	0.0212765957446809	1.37222999337407	0.520669264386379	0.670381888157675
GO:0009378	four-way junction helicase activity	1/289	48/18639	0.0208333333333333	1.34364186851211	0.528120134792593	0.670381888157675
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/289	48/18639	0.0208333333333333	1.34364186851211	0.528120134792593	0.670381888157675
GO:0036121	double-stranded DNA helicase activity	1/289	48/18639	0.0208333333333333	1.34364186851211	0.528120134792593	0.670381888157675
GO:0043138	3'-5' DNA helicase activity	1/289	48/18639	0.0208333333333333	1.34364186851211	0.528120134792593	0.670381888157675
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	3/289	181/18639	0.0165745856353591	1.06897474621958	0.53450275140643	0.670381888157675
GO:0035401	histone H3Y41 kinase activity	2/289	115/18639	0.0173913043478261	1.12164886414924	0.534665205111035	0.670381888157675
GO:0140801	histone H2AXY142 kinase activity	2/289	115/18639	0.0173913043478261	1.12164886414924	0.534665205111035	0.670381888157675
GO:0042393	histone binding	4/289	247/18639	0.0161943319838057	1.04445035932925	0.535017793672489	0.670381888157675
GO:0005004	GPI-linked ephrin receptor activity	1/289	49/18639	0.0204081632653061	1.31622060588941	0.535455581032437	0.670381888157675
GO:0005008	hepatocyte growth factor receptor activity	1/289	49/18639	0.0204081632653061	1.31622060588941	0.535455581032437	0.670381888157675
GO:0005009	insulin receptor activity	1/289	49/18639	0.0204081632653061	1.31622060588941	0.535455581032437	0.670381888157675
GO:0005011	macrophage colony-stimulating factor receptor activity	1/289	49/18639	0.0204081632653061	1.31622060588941	0.535455581032437	0.670381888157675
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/289	49/18639	0.0204081632653061	1.31622060588941	0.535455581032437	0.670381888157675
GO:0005020	stem cell factor receptor activity	1/289	49/18639	0.0204081632653061	1.31622060588941	0.535455581032437	0.670381888157675
GO:0008288	boss receptor activity	1/289	49/18639	0.0204081632653061	1.31622060588941	0.535455581032437	0.670381888157675
GO:0035254	glutamate receptor binding	1/289	49/18639	0.0204081632653061	1.31622060588941	0.535455581032437	0.670381888157675
GO:0036332	placental growth factor receptor activity	1/289	49/18639	0.0204081632653061	1.31622060588941	0.535455581032437	0.670381888157675
GO:0038062	protein tyrosine kinase collagen receptor activity	1/289	49/18639	0.0204081632653061	1.31622060588941	0.535455581032437	0.670381888157675
GO:0060175	brain-derived neurotrophic factor receptor activity	1/289	49/18639	0.0204081632653061	1.31622060588941	0.535455581032437	0.670381888157675
GO:0005006	epidermal growth factor receptor activity	1/289	50/18639	0.02	1.28989619377163	0.542677385071255	0.672749371276939
GO:0005007	fibroblast growth factor receptor activity	1/289	50/18639	0.02	1.28989619377163	0.542677385071255	0.672749371276939
GO:0005017	platelet-derived growth factor receptor activity	1/289	50/18639	0.02	1.28989619377163	0.542677385071255	0.672749371276939
GO:0005019	platelet-derived growth factor beta-receptor activity	1/289	50/18639	0.02	1.28989619377163	0.542677385071255	0.672749371276939
GO:0032813	tumor necrosis factor receptor superfamily binding	1/289	50/18639	0.02	1.28989619377163	0.542677385071255	0.672749371276939
GO:0061135	endopeptidase regulator activity	3/289	184/18639	0.016304347826087	1.05154581013991	0.545618179511947	0.673622887805901
GO:0005010	insulin-like growth factor receptor activity	1/289	51/18639	0.0196078431372549	1.26460411154081	0.549787301458065	0.673622887805901
GO:0005021	vascular endothelial growth factor receptor activity	1/289	51/18639	0.0196078431372549	1.26460411154081	0.549787301458065	0.673622887805901
GO:0005030	neurotrophin receptor activity	1/289	51/18639	0.0196078431372549	1.26460411154081	0.549787301458065	0.673622887805901
GO:0005048	signal sequence binding	1/289	51/18639	0.0196078431372549	1.26460411154081	0.549787301458065	0.673622887805901
GO:0016830	carbon-carbon lyase activity	1/289	51/18639	0.0196078431372549	1.26460411154081	0.549787301458065	0.673622887805901
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/289	52/18639	0.0192307692307692	1.24028480170349	0.556787057745919	0.679560219415231
GO:0030159	signaling receptor complex adaptor activity	1/289	52/18639	0.0192307692307692	1.24028480170349	0.556787057745919	0.679560219415231
GO:0015108	chloride transmembrane transporter activity	2/289	121/18639	0.0165289256198347	1.06602991220796	0.562206103459022	0.681381306409165
GO:0005003	ephrin receptor activity	1/289	53/18639	0.0188679245283019	1.21688320167135	0.563678354905838	0.681381306409165
GO:0005005	transmembrane-ephrin receptor activity	1/289	53/18639	0.0188679245283019	1.21688320167135	0.563678354905838	0.681381306409165
GO:0038064	collagen receptor activity	1/289	53/18639	0.0188679245283019	1.21688320167135	0.563678354905838	0.681381306409165
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/289	53/18639	0.0188679245283019	1.21688320167135	0.563678354905838	0.681381306409165
GO:0022804	active transmembrane transporter activity	7/289	457/18639	0.0153172866520788	0.987885487571267	0.566222009708509	0.683147396034549
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	1/289	54/18639	0.0185185185185185	1.19434832756632	0.57046286773443	0.684338535247957
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	1/289	54/18639	0.0185185185185185	1.19434832756632	0.57046286773443	0.684338535247957
GO:0140463	chromatin-protein adaptor activity	1/289	54/18639	0.0185185185185185	1.19434832756632	0.57046286773443	0.684338535247957
GO:0098632	cell-cell adhesion mediator activity	1/289	55/18639	0.0181818181818182	1.17263290342875	0.577142245255267	0.691037489100709
GO:0003730	mRNA 3'-UTR binding	4/289	262/18639	0.0152671755725191	0.984653583031776	0.581647287764685	0.695112573067265
GO:0170055	lipid transmembrane transporter activity	1/289	56/18639	0.0178571428571429	1.15169303015324	0.583718111114137	0.696268673181513
GO:0004519	endonuclease activity	2/289	127/18639	0.015748031496063	1.01566629430837	0.588564190648318	0.700724536413375
GO:0016504	peptidase activator activity	1/289	57/18639	0.0175438596491228	1.13148788927336	0.590192063968251	0.701339345318205
GO:0008408	3'-5' exonuclease activity	1/289	58/18639	0.0172413793103448	1.11197947738933	0.596565677869509	0.704954050292184
GO:0017116	single-stranded DNA helicase activity	1/289	58/18639	0.0172413793103448	1.11197947738933	0.596565677869509	0.704954050292184
GO:0016757	glycosyltransferase activity	4/289	267/18639	0.0149812734082397	0.966214377357023	0.596585519581658	0.704954050292184
GO:0004714	transmembrane receptor protein tyrosine kinase activity	1/289	60/18639	0.0166666666666667	1.07491349480969	0.609018064253117	0.716959698775591
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	1/289	60/18639	0.0166666666666667	1.07491349480969	0.609018064253117	0.716959698775591
GO:0019905	syntaxin binding	1/289	61/18639	0.0163934426229508	1.05729196210789	0.615099865180554	0.722770977521284
GO:0015297	antiporter activity	2/289	135/18639	0.0148148148148148	0.955478662053057	0.621853504309007	0.728941653492872
GO:0008017	microtubule binding	4/289	276/18639	0.0144927536231884	0.934707386791033	0.622661729370298	0.728941653492872
GO:0005507	copper ion binding	1/289	63/18639	0.0158730158730159	1.02372713791399	0.62698207959861	0.732640170790228
GO:0140101	catalytic activity, acting on a tRNA	2/289	139/18639	0.0143884892086331	0.927982873216997	0.637704852088001	0.743344438510182
GO:0160215	deacylase activity	1/289	65/18639	0.0153846153846154	0.992227841362789	0.638498709465164	0.743344438510182
GO:0004713	protein tyrosine kinase activity	2/289	140/18639	0.0142857142857143	0.92135442412259	0.641585547102785	0.745562578677454
GO:1990841	promoter-specific chromatin binding	1/289	68/18639	0.0147058823529412	0.948453083655608	0.655112611626182	0.759882459441399
GO:0016279	protein-lysine N-methyltransferase activity	1/289	69/18639	0.0144927536231884	0.934707386791033	0.660479713841466	0.764702200796265
GO:0016278	lysine N-methyltransferase activity	1/289	70/18639	0.0142857142857143	0.92135442412259	0.665763578284105	0.768001495241811
GO:0016782	transferase activity, transferring sulphur-containing groups	1/289	70/18639	0.0142857142857143	0.92135442412259	0.665763578284105	0.768001495241811
GO:0005518	collagen binding	1/289	72/18639	0.0138888888888889	0.89576124567474	0.676086720083384	0.777068707418243
GO:0042379	chemokine receptor binding	1/289	72/18639	0.0138888888888889	0.89576124567474	0.676086720083384	0.777068707418243
GO:0004521	RNA endonuclease activity	1/289	73/18639	0.0136986301369863	0.883490543679196	0.681128511320305	0.780021943090948
GO:0043539	protein serine/threonine kinase activator activity	1/289	73/18639	0.0136986301369863	0.883490543679196	0.681128511320305	0.780021943090948
GO:0061134	peptidase regulator activity	3/289	226/18639	0.0132743362831858	0.856125792326301	0.683777191663188	0.781636608585999
GO:0003678	DNA helicase activity	1/289	74/18639	0.0135135135135135	0.871551482278126	0.686092093148832	0.782864576450114
GO:0003774	cytoskeletal motor activity	2/289	153/18639	0.0130718954248366	0.843069407693873	0.689090443239021	0.784866551775852
GO:0098631	cell adhesion mediator activity	1/289	76/18639	0.0131578947368421	0.848615916955017	0.695789446172549	0.791068721684465
GO:0019199	transmembrane receptor protein kinase activity	1/289	78/18639	0.0128205128205128	0.826856534468991	0.705188229780802	0.800312541351954
GO:0015370	solute:sodium symporter activity	1/289	79/18639	0.0126582278481013	0.816389996057991	0.709778532113293	0.802634863375426
GO:0046332	SMAD binding	1/289	79/18639	0.0126582278481013	0.816389996057991	0.709778532113293	0.802634863375426
GO:0004866	endopeptidase inhibitor activity	2/289	161/18639	0.0124223602484472	0.8011777601066	0.715676879036165	0.806414483342536
GO:0005178	integrin binding	2/289	161/18639	0.0124223602484472	0.8011777601066	0.715676879036165	0.806414483342536
GO:0001618	virus receptor activity	1/289	81/18639	0.0123456790123457	0.796232218377547	0.718746551786906	0.806852110534379
GO:0008083	growth factor activity	2/289	162/18639	0.0123456790123457	0.796232218377547	0.718862848604793	0.806852110534379
GO:0140098	catalytic activity, acting on RNA	5/289	387/18639	0.0129198966408269	0.83326627504627	0.71990132841657	0.806852110534379
GO:0140272	exogenous protein binding	1/289	82/18639	0.0121951219512195	0.786522069372943	0.723126455145758	0.809029775171939
GO:0005254	chloride channel activity	1/289	83/18639	0.0120481927710843	0.777045899862425	0.727438383499634	0.812413486704901
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	1/289	86/18639	0.0116279069767442	0.749939647541643	0.73997675124177	0.821002669667556
GO:0050660	flavin adenine dinucleotide binding	1/289	86/18639	0.0116279069767442	0.749939647541643	0.73997675124177	0.821002669667556
GO:0033218	amide binding	3/289	247/18639	0.0121457489878543	0.783337769496939	0.740086511182084	0.821002669667556
GO:0030414	peptidase inhibitor activity	2/289	169/18639	0.0118343195266272	0.763252185663684	0.740333627639999	0.821002669667556
GO:0042277	peptide binding	3/289	249/18639	0.0120481927710843	0.777045899862425	0.745011850260413	0.824741188621615
GO:0004175	endopeptidase activity	5/289	405/18639	0.0123456790123457	0.796232218377547	0.755816994868497	0.835237344591981
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	1/289	91/18639	0.010989010989011	0.708734172401993	0.759609530857587	0.835847822041921
GO:0072341	modified amino acid binding	1/289	91/18639	0.010989010989011	0.708734172401993	0.759609530857587	0.835847822041921
GO:0004252	serine-type endopeptidase activity	2/289	176/18639	0.0113636363636364	0.732895564642969	0.76039171966384	0.835847822041921
GO:0003713	transcription coactivator activity	3/289	256/18639	0.01171875	0.755798551038062	0.761667983635665	0.835847822041921
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	6/289	484/18639	0.012396694214876	0.799522434155967	0.764775854180138	0.837801326367478
GO:0016410	N-acyltransferase activity	1/289	94/18639	0.0106382978723404	0.686114996687035	0.770672658060681	0.841339874111227
GO:0042562	hormone binding	1/289	94/18639	0.0106382978723404	0.686114996687035	0.770672658060681	0.841339874111227
GO:0004867	serine-type endopeptidase inhibitor activity	1/289	95/18639	0.0105263157894737	0.678892733564014	0.774246430065019	0.842326719605219
GO:0008276	protein methyltransferase activity	1/289	95/18639	0.0105263157894737	0.678892733564014	0.774246430065019	0.842326719605219
GO:0001216	DNA-binding transcription activator activity	6/289	491/18639	0.0122199592668024	0.788123947314639	0.776498186548256	0.843322471104904
GO:1901981	phosphatidylinositol phosphate binding	2/289	185/18639	0.0108108108108108	0.697241185822501	0.784203562824979	0.849239577289289
GO:0008170	N-methyltransferase activity	1/289	98/18639	0.0102040816326531	0.658110302944707	0.784638151441609	0.849239577289289
GO:0008234	cysteine-type peptidase activity	2/289	187/18639	0.0106951871657754	0.689784060840442	0.789205259009932	0.852720065813814
GO:1901681	sulfur compound binding	3/289	275/18639	0.0109090909090909	0.703579742057251	0.802469624604238	0.865569800214144
GO:0008236	serine-type peptidase activity	2/289	194/18639	0.0103092783505155	0.664894945243106	0.805917013496256	0.867804838764739
GO:0004497	monooxygenase activity	1/289	106/18639	0.00943396226415094	0.608441600835673	0.810077318989389	0.870798617175987
GO:0016758	hexosyltransferase activity	2/289	197/18639	0.0101522842639594	0.65476964150844	0.812712454969391	0.872145508649125
GO:0017171	serine hydrolase activity	2/289	198/18639	0.0101010101010101	0.651462724127084	0.814930103325663	0.872656453011833
GO:0004843	cysteine-type deubiquitinase activity	1/289	108/18639	0.00925925925925926	0.59717416378316	0.815954528172713	0.872656453011833
GO:0004620	phospholipase activity	1/289	109/18639	0.00917431192660551	0.591695501730104	0.818824807237959	0.874244421941036
GO:1902936	phosphatidylinositol bisphosphate binding	1/289	111/18639	0.00900900900900901	0.581034321518751	0.824432223593656	0.878744481566887
GO:0005200	structural constituent of cytoskeleton	1/289	112/18639	0.00892857142857143	0.575846515076619	0.827170732195849	0.880176613854268
GO:0017124	SH3 domain binding	1/289	115/18639	0.00869565217391304	0.56082443207462	0.835133467008701	0.885662550726874
GO:0101005	deubiquitinase activity	1/289	115/18639	0.00869565217391304	0.56082443207462	0.835133467008701	0.885662550726874
GO:0015294	solute:monoatomic cation symporter activity	1/289	116/18639	0.00862068965517241	0.555989738694667	0.837705612767418	0.886899734322552
GO:0004540	RNA nuclease activity	1/289	121/18639	0.00826446280991736	0.533014956103978	0.849978707608376	0.897852960670008
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/289	122/18639	0.00819672131147541	0.528645981053945	0.852320005453779	0.897852960670008
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	1/289	122/18639	0.00819672131147541	0.528645981053945	0.852320005453779	0.897852960670008
GO:0019783	ubiquitin-like protein peptidase activity	1/289	127/18639	0.0078740157480315	0.507833147154184	0.86349143063293	0.908105154548965
GO:0035591	signaling adaptor activity	1/289	129/18639	0.00775193798449612	0.499959765027762	0.867720480022939	0.908666936858922
GO:0016298	lipase activity	1/289	130/18639	0.00769230769230769	0.496113920681395	0.869785784251646	0.908666936858922
GO:0016798	hydrolase activity, acting on glycosyl bonds	1/289	130/18639	0.00769230769230769	0.496113920681395	0.869785784251646	0.908666936858922
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1/289	130/18639	0.00769230769230769	0.496113920681395	0.869785784251646	0.908666936858922
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	1/289	132/18639	0.00757575757575758	0.488597043095313	0.873820482649838	0.911373098433137
GO:0016779	nucleotidyltransferase activity	1/289	136/18639	0.00735294117647059	0.474226541827804	0.881519925358818	0.916374090447141
GO:0019838	growth factor binding	1/289	136/18639	0.00735294117647059	0.474226541827804	0.881519925358818	0.916374090447141
GO:0016922	nuclear receptor binding	1/289	137/18639	0.0072992700729927	0.470765034223221	0.883370476165244	0.916787451414916
GO:0140767	enzyme-substrate adaptor activity	1/289	139/18639	0.00719424460431655	0.463991436608499	0.886985608246008	0.919027781286093
GO:0019955	cytokine binding	1/289	144/18639	0.00694444444444444	0.44788062283737	0.895542324849471	0.926372470459043
GO:0015293	symporter activity	1/289	146/18639	0.00684931506849315	0.441745271839598	0.898781385453152	0.928201398070277
GO:0003779	actin binding	4/289	443/18639	0.0090293453724605	0.582345911409312	0.915387095276954	0.943805975685879
GO:0015081	sodium ion transmembrane transporter activity	1/289	164/18639	0.00609756097560976	0.393261034686471	0.923779193695594	0.950904847017814
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	1/289	167/18639	0.00598802395209581	0.386196465201086	0.927300631745125	0.952975079203866
GO:0008201	heparin binding	1/289	172/18639	0.00581395348837209	0.374969823770822	0.932813039608469	0.956395967678325
GO:0005244	voltage-gated monoatomic ion channel activity	1/289	173/18639	0.00578034682080925	0.372802368142089	0.933864484431838	0.956395967678325
GO:0022832	voltage-gated channel activity	1/289	175/18639	0.00571428571428571	0.368541769649036	0.935918433231552	0.956395967678325
GO:0035091	phosphatidylinositol binding	2/289	284/18639	0.00704225352112676	0.454188800623812	0.936692088787963	0.956395967678325
GO:0015291	secondary active transmembrane transporter activity	2/289	287/18639	0.00696864111498258	0.449441182498825	0.93910485134231	0.957310438121159
GO:0015276	ligand-gated monoatomic ion channel activity	1/289	186/18639	0.00537634408602151	0.346746288648287	0.946129940926922	0.962916117298206
GO:0022834	ligand-gated channel activity	1/289	188/18639	0.00531914893617021	0.343057498343518	0.947804134869553	0.963066681324779
GO:0022836	gated channel activity	2/289	318/18639	0.00628930817610063	0.405627733890449	0.959426935589708	0.971779796464209
GO:0008168	methyltransferase activity	1/289	204/18639	0.00490196078431373	0.316151027885202	0.959459291913157	0.971779796464209
GO:0051015	actin filament binding	1/289	209/18639	0.00478468899521531	0.308587606165461	0.962539255852915	0.973336971864086
GO:0016741	transferase activity, transferring one-carbon groups	1/289	215/18639	0.00465116279069767	0.299975859016657	0.965928904583334	0.975201822067334
GO:0046873	metal ion transmembrane transporter activity	3/289	450/18639	0.00666666666666667	0.429965397923875	0.972059362129452	0.979823414542626
GO:0005539	glycosaminoglycan binding	1/289	242/18639	0.00413223140495868	0.266507478051989	0.977773951342214	0.984011743695274
GO:0005543	phospholipid binding	3/289	497/18639	0.00603621730382294	0.389304686248982	0.984288939424771	0.988643731199938
GO:0008514	organic anion transmembrane transporter activity	1/289	269/18639	0.00371747211895911	0.239757656834875	0.985510153605009	0.988643731199938
GO:0030246	carbohydrate binding	1/289	280/18639	0.00357142857142857	0.230338606030648	0.987830039207874	0.989398023397092
GO:0005216	monoatomic ion channel activity	2/289	448/18639	0.00446428571428571	0.287923257538309	0.993116946941172	0.993116946941172