ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0023023	MHC protein complex binding	17/1659	37/18639	0.459459459459459	5.16206441522897	3.59590430583676e-09	4.4804967650726e-06
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	23/1659	68/18639	0.338235294117647	3.80010105307946	9.24422734761445e-09	5.0846059168206e-06
GO:0023026	MHC class II protein complex binding	14/1659	27/18639	0.518518518518518	5.82559774964838	1.2242229334239e-08	5.0846059168206e-06
GO:0031625	ubiquitin protein ligase binding	56/1659	302/18639	0.185430463576159	2.08332634755638	9.60470674377955e-08	2.99186615068733e-05
GO:0003735	structural constituent of ribosome	38/1659	175/18639	0.217142857142857	2.43961766985275	1.86740360487398e-07	4.65356978334595e-05
GO:0044389	ubiquitin-like protein ligase binding	57/1659	322/18639	0.177018633540373	1.98881875259735	3.73253916422894e-07	7.01338453315813e-05
GO:0003712	transcription coregulator activity	78/1659	495/18639	0.157575757575758	1.77037645898405	4.47487688371373e-07	7.01338453315813e-05
GO:0016651	oxidoreductase activity, acting on NAD(P)H	24/1659	88/18639	0.272727272727273	3.06411310208779	4.50297562321549e-07	7.01338453315813e-05
GO:0045296	cadherin binding	58/1659	334/18639	0.173652694610778	1.95100215482236	5.71376250185996e-07	7.91038675257501e-05
GO:0042605	peptide antigen binding	16/1659	45/18639	0.355555555555556	3.99469559975889	7.68451810567491e-07	9.57490955967094e-05
GO:0008137	NADH dehydrogenase (ubiquinone) activity	15/1659	41/18639	0.365853658536585	4.11039562475191	1.11529052608614e-06	0.000126331999591212
GO:0042277	peptide binding	46/1659	249/18639	0.184738955823293	2.07555720168195	1.45755854515821e-06	0.000151343162272261
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	18/1659	58/18639	0.310344827586207	3.48674939203093	1.58080264094633e-06	0.000151513853124549
GO:0009055	electron transfer activity	27/1659	116/18639	0.232758620689655	2.6150620440232	2.66651167540729e-06	0.000237319539111249
GO:0003954	NADH dehydrogenase activity	15/1659	44/18639	0.340909090909091	3.83014137760973	3.12760315753728e-06	0.000259799568952763
GO:0140297	DNA-binding transcription factor binding	74/1659	488/18639	0.151639344262295	1.7036803723357	3.75628083169617e-06	0.000292520369768339
GO:0015078	proton transmembrane transporter activity	36/1659	185/18639	0.194594594594595	2.18628610527345	5.8600194893812e-06	0.000429504957868763
GO:0003713	transcription coactivator activity	45/1659	256/18639	0.17578125	1.97491664783002	7.38588998608069e-06	0.000511267717925363
GO:0022853	active monoatomic ion transmembrane transporter activity	26/1659	118/18639	0.220338983050847	2.4755264045116	1.17004491972104e-05	0.000767303142090748
GO:0140375	immune receptor activity	31/1659	156/18639	0.198717948717949	2.23261232438448	1.64642555224449e-05	0.00102572311904832
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	55/1659	349/18639	0.157593123209169	1.77057156328855	2.15880773098611e-05	0.00128089258705176
GO:0032395	MHC class II receptor activity	6/1659	10/18639	0.6	6.74104882459313	7.55360326178473e-05	0.00427808621099262
GO:0005543	phospholipid binding	69/1659	497/18639	0.138832997987928	1.55980002983543	0.000136787044526942	0.00741028945567694
GO:0042393	histone binding	40/1659	247/18639	0.161943319838057	1.8194463764084	0.000151211210859219	0.00765688348888488
GO:0042608	T cell receptor binding	6/1659	11/18639	0.545454545454545	6.12822620417557	0.000153629283484849	0.00765688348888488
GO:0016922	nuclear receptor binding	26/1659	137/18639	0.18978102189781	2.13220522432386	0.000168994737086617	0.0080987477849971
GO:0140311	protein sequestering activity	10/1659	33/18639	0.303030303030303	3.40457011343087	0.000416012564294656	0.0191982094485608
GO:0019843	rRNA binding	15/1659	65/18639	0.230769230769231	2.59271108638197	0.000472957924226037	0.0210466276280586
GO:0046332	SMAD binding	17/1659	79/18639	0.215189873417722	2.41767573877813	0.000490577158911262	0.0210779013794287
GO:0030331	nuclear estrogen receptor binding	11/1659	40/18639	0.275	3.08964737793852	0.00054856568319617	0.0227837613754143
GO:0050840	extracellular matrix binding	15/1659	67/18639	0.223880597014925	2.51531672559445	0.000665957714281274	0.0267672036127248
GO:0140104	molecular carrier activity	38/1659	249/18639	0.152610441767068	1.71459073182422	0.000718358933935372	0.027514747905714
GO:0015399	primary active transmembrane transporter activity	28/1659	166/18639	0.168674698795181	1.89507396675309	0.000728721252719552	0.027514747905714
GO:0140313	molecular sequestering activity	13/1659	55/18639	0.236363636363636	2.65556468847608	0.000870775564930127	0.0319113633500864
GO:0002039	p53 binding	15/1659	69/18639	0.217391304347826	2.4424089944178	0.00092214420179275	0.0328283335838219
GO:0070325	lipoprotein particle receptor binding	9/1659	31/18639	0.290322580645161	3.26179781835151	0.00113482543239637	0.0378198522636484
GO:0003714	transcription corepressor activity	32/1659	204/18639	0.156862745098039	1.76236570577598	0.00114518226808214	0.0378198522636484
GO:0017124	SH3 domain binding	21/1659	115/18639	0.182608695652174	2.05162355531095	0.00115341443500693	0.0378198522636484
GO:0140030	modification-dependent protein binding	28/1659	173/18639	0.161849710982659	1.81839467330065	0.0014001607941123	0.0447333422939469
GO:0038024	cargo receptor activity	14/1659	65/18639	0.215384615384615	2.41986368062317	0.00148330263935685	0.0462048772159658
GO:0019207	kinase regulator activity	41/1659	287/18639	0.142857142857143	1.60501162490313	0.00169120442086543	0.0513961148389836
GO:0019838	growth factor binding	23/1659	136/18639	0.169117647058824	1.90005052653973	0.00200606391611125	0.0595132295113004
GO:0008429	phosphatidylethanolamine binding	6/1659	17/18639	0.352941176470588	3.96532283799596	0.00257727713189748	0.0730424372632624
GO:0035014	phosphatidylinositol 3-kinase regulator activity	5/1659	12/18639	0.416666666666667	4.68128390596745	0.00257934770432066	0.0730424372632624
GO:0051117	ATPase binding	16/1659	84/18639	0.19047619047619	2.14001549987083	0.00274145387064737	0.0759078116183695
GO:0043130	ubiquitin binding	18/1659	100/18639	0.18	2.02231464737794	0.00295799700280782	0.0801231362064901
GO:0051861	glycolipid binding	8/1659	29/18639	0.275862068965517	3.09933279291638	0.00303276830580607	0.080265287746256
GO:0097110	scaffold protein binding	14/1659	70/18639	0.2	2.24701627486438	0.00309208171093121	0.080265287746256
GO:0016209	antioxidant activity	16/1659	86/18639	0.186046511627907	2.09024769754826	0.00350568514292348	0.0874101952006219
GO:0032393	MHC class I receptor activity	6/1659	18/18639	0.333333333333333	3.74502712477396	0.00357778487578789	0.0874101952006219
GO:0035615	clathrin adaptor activity	6/1659	18/18639	0.333333333333333	3.74502712477396	0.00357778487578789	0.0874101952006219
GO:0004601	peroxidase activity	12/1659	57/18639	0.210526315789474	2.36528028933092	0.00384555017141626	0.0880468849890433
GO:0016504	peptidase activator activity	12/1659	57/18639	0.210526315789474	2.36528028933092	0.00384555017141626	0.0880468849890433
GO:0019104	DNA N-glycosylase activity	5/1659	13/18639	0.384615384615385	4.32118514396995	0.00388649973868169	0.0880468849890433
GO:0032396	inhibitory MHC class I receptor activity	5/1659	13/18639	0.384615384615385	4.32118514396995	0.00388649973868169	0.0880468849890433
GO:0005178	integrin binding	25/1659	161/18639	0.15527950310559	1.74457785315557	0.00429949178675502	0.0956636922552991
GO:0004197	cysteine-type endopeptidase activity	16/1659	88/18639	0.181818181818182	2.04274206805852	0.00443706057932423	0.0956808183124767
GO:0032182	ubiquitin-like protein binding	20/1659	120/18639	0.166666666666667	1.87251356238698	0.00450991504357928	0.0956808183124767
GO:0030547	signaling receptor inhibitor activity	10/1659	44/18639	0.227272727272727	2.55342758507315	0.00453063264882514	0.0956808183124767
GO:0042974	nuclear retinoic acid receptor binding	7/1659	25/18639	0.28	3.14582278481013	0.00500413216419292	0.10370446239837
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/1659	59/18639	0.203389830508475	2.28510129647225	0.00516025414823351	0.10370446239837
GO:0045309	protein phosphorylated amino acid binding	12/1659	59/18639	0.203389830508475	2.28510129647225	0.00516025414823351	0.10370446239837
GO:0030159	signaling receptor complex adaptor activity	11/1659	52/18639	0.211538461538462	2.37665182918347	0.00533140405207659	0.105443324585515
GO:0019902	phosphatase binding	28/1659	190/18639	0.147368421052632	1.65569620253165	0.00552777997997133	0.107480785487387
GO:0044548	S100 protein binding	5/1659	14/18639	0.357142857142857	4.01252906225781	0.00560694306314618	0.107480785487387
GO:0050750	low-density lipoprotein particle receptor binding	7/1659	26/18639	0.269230769230769	3.02482960077897	0.00633051140795372	0.119043556245338
GO:0042288	MHC class I protein binding	6/1659	20/18639	0.3	3.37052441229656	0.0064012185139949	0.119043556245338
GO:0017069	snRNA binding	11/1659	54/18639	0.203703703703704	2.28862768736186	0.00717292590231639	0.131433318739503
GO:0035091	phosphatidylinositol binding	38/1659	284/18639	0.133802816901408	1.50328553600081	0.00736691986923776	0.133031625464786
GO:0051219	phosphoprotein binding	16/1659	93/18639	0.172043010752688	1.93291722568979	0.0076701565501048	0.136528786591865
GO:0140312	cargo adaptor activity	6/1659	21/18639	0.285714285714286	3.21002324980625	0.00829788101756973	0.144621799421714
GO:0031720	haptoglobin binding	4/1659	10/18639	0.4	4.49403254972875	0.00847302677189815	0.144621799421714
GO:0045322	unmethylated CpG binding	4/1659	10/18639	0.4	4.49403254972875	0.00847302677189815	0.144621799421714
GO:0008376	acetylgalactosaminyltransferase activity	8/1659	34/18639	0.235294117647059	2.64354855866397	0.00861294670003184	0.145023399841077
GO:0046966	nuclear thyroid hormone receptor binding	7/1659	28/18639	0.25	2.80877034358047	0.00974263577229261	0.159727949635218
GO:0097718	disordered domain specific binding	7/1659	28/18639	0.25	2.80877034358047	0.00974263577229261	0.159727949635218
GO:0140097	catalytic activity, acting on DNA	43/1659	336/18639	0.12797619047619	1.43782291397572	0.00991530117929715	0.160447600901354
GO:0017070	U6 snRNA binding	5/1659	16/18639	0.3125	3.51096292947559	0.0105286770351881	0.164569059707749
GO:0034450	ubiquitin-ubiquitin ligase activity	5/1659	16/18639	0.3125	3.51096292947559	0.0105286770351881	0.164569059707749
GO:0061133	endopeptidase activator activity	6/1659	22/18639	0.272727272727273	3.06411310208779	0.0105662317629373	0.164569059707749
GO:0003779	actin binding	54/1659	443/18639	0.121896162528217	1.36951330522208	0.0110600132900092	0.170133043942611
GO:0019887	protein kinase regulator activity	34/1659	255/18639	0.133333333333333	1.49801084990958	0.0113593125533129	0.172606139529608
GO:0019209	kinase activator activity	22/1659	148/18639	0.148648648648649	1.67007966375055	0.0116858083492986	0.175393359509949
GO:0033218	amide binding	33/1659	247/18639	0.133603238866397	1.50104326053693	0.0121402561071746	0.175393359509949
GO:0016409	palmitoyltransferase activity	8/1659	36/18639	0.222222222222222	2.49668474984931	0.0122506114429675	0.175393359509949
GO:0055106	ubiquitin-protein transferase regulator activity	8/1659	36/18639	0.222222222222222	2.49668474984931	0.0122506114429675	0.175393359509949
GO:0019864	IgG binding	4/1659	11/18639	0.363636363636364	4.08548413611705	0.0123873319718102	0.175393359509949
GO:1990948	ubiquitin ligase inhibitor activity	4/1659	11/18639	0.363636363636364	4.08548413611705	0.0123873319718102	0.175393359509949
GO:0003684	damaged DNA binding	13/1659	74/18639	0.175675675675676	1.9737305117052	0.012958645217115	0.181301227130447
GO:0005048	signal sequence binding	10/1659	51/18639	0.196078431372549	2.20295713221998	0.0132273930376809	0.181301227130447
GO:0070577	lysine-acetylated histone binding	6/1659	23/18639	0.260869565217391	2.93089079330136	0.0132411008578416	0.181301227130447
GO:1990226	histone methyltransferase binding	5/1659	17/18639	0.294117647058824	3.30443569832996	0.0138417603282258	0.187372825424302
GO:0001968	fibronectin binding	7/1659	30/18639	0.233333333333333	2.62151898734177	0.0143305380963212	0.187372825424302
GO:0031210	phosphatidylcholine binding	7/1659	30/18639	0.233333333333333	2.62151898734177	0.0143305380963212	0.187372825424302
GO:0001540	amyloid-beta binding	14/1659	83/18639	0.168674698795181	1.89507396675309	0.0143516202788344	0.187372825424302
GO:0003725	double-stranded RNA binding	13/1659	75/18639	0.173333333333333	1.94741410488246	0.0144364295672014	0.187372825424302
GO:0140597	protein carrier chaperone	26/1659	188/18639	0.138297872340426	1.55378784964026	0.0160400728461453	0.204284996527883
GO:0035035	histone acetyltransferase binding	6/1659	24/18639	0.25	2.80877034358047	0.016355499172636	0.204284996527883
GO:0140033	acetylation-dependent protein binding	6/1659	24/18639	0.25	2.80877034358047	0.016355499172636	0.204284996527883
GO:0005125	cytokine activity	31/1659	234/18639	0.132478632478632	1.48840821625632	0.0164351967702328	0.204284996527883
GO:0019955	cytokine binding	21/1659	144/18639	0.145833333333333	1.63844936708861	0.0165592172145395	0.204284996527883
GO:0140296	general transcription initiation factor binding	10/1659	53/18639	0.188679245283019	2.11982667440035	0.0171791767352104	0.207163363803091
GO:0000340	RNA 7-methylguanosine cap binding	4/1659	12/18639	0.333333333333333	3.74502712477396	0.017291324105555	0.207163363803091
GO:0070008	serine-type exopeptidase activity	4/1659	12/18639	0.333333333333333	3.74502712477396	0.017291324105555	0.207163363803091
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	5/1659	18/18639	0.277777777777778	3.12085593731163	0.017789443194548	0.208472533751166
GO:0099602	neurotransmitter receptor regulator activity	5/1659	18/18639	0.277777777777778	3.12085593731163	0.017789443194548	0.208472533751166
GO:0004857	enzyme inhibitor activity	50/1659	416/18639	0.120192307692308	1.35037035749061	0.0179025370075239	0.208472533751166
GO:0030276	clathrin binding	9/1659	46/18639	0.195652173913043	2.19816809497602	0.0185325243460577	0.213810419770258
GO:0140713	histone chaperone activity	23/1659	164/18639	0.140243902439024	1.5756516561549	0.0193805897799862	0.220475245766918
GO:0019706	protein-cysteine S-palmitoyltransferase activity	6/1659	25/18639	0.24	2.69641952983725	0.0199401413858286	0.220475245766918
GO:0019707	protein-cysteine S-acyltransferase activity	6/1659	25/18639	0.24	2.69641952983725	0.0199401413858286	0.220475245766918
GO:0120020	cholesterol transfer activity	6/1659	25/18639	0.24	2.69641952983725	0.0199401413858286	0.220475245766918
GO:0005126	cytokine receptor binding	35/1659	275/18639	0.127272727272727	1.42991944764097	0.0199949460446723	0.220475245766918
GO:0005504	fatty acid binding	9/1659	47/18639	0.191489361702128	2.15139856104036	0.0211669760851374	0.231351335105976
GO:0030295	protein kinase activator activity	20/1659	139/18639	0.143884892086331	1.61655847112545	0.0217256253727662	0.235392427951884
GO:0097001	ceramide binding	5/1659	19/18639	0.263157894736842	2.95660036166365	0.0224141987833687	0.238701638325448
GO:0140036	ubiquitin-modified protein reader activity	5/1659	19/18639	0.263157894736842	2.95660036166365	0.0224141987833687	0.238701638325448
GO:0032451	demethylase activity	8/1659	40/18639	0.2	2.24701627486438	0.0227103201159848	0.239805583597602
GO:0140852	histone ubiquitin ligase activity	4/1659	13/18639	0.307692307692308	3.45694811517596	0.0232490238241654	0.243430955335379
GO:0043548	phosphatidylinositol 3-kinase binding	6/1659	26/18639	0.230769230769231	2.59271108638197	0.0240230303791909	0.247377651673322
GO:0070412	R-SMAD binding	6/1659	26/18639	0.230769230769231	2.59271108638197	0.0240230303791909	0.247377651673322
GO:0001221	transcription coregulator binding	17/1659	115/18639	0.147826086956522	1.6608381162041	0.0257583794097538	0.26307328479142
GO:0031267	small GTPase binding	35/1659	283/18639	0.123674911660777	1.3894976964709	0.0292549512613441	0.292159721589388
GO:0031491	nucleosome binding	12/1659	74/18639	0.162162162162162	1.82190508772787	0.0296162447674208	0.292159721589388
GO:0005344	oxygen carrier activity	4/1659	14/18639	0.285714285714286	3.21002324980625	0.030305856128573	0.292159721589388
GO:0008191	metalloendopeptidase inhibitor activity	4/1659	14/18639	0.285714285714286	3.21002324980625	0.030305856128573	0.292159721589388
GO:0016530	metallochaperone activity	4/1659	14/18639	0.285714285714286	3.21002324980625	0.030305856128573	0.292159721589388
GO:0019763	immunoglobulin receptor activity	4/1659	14/18639	0.285714285714286	3.21002324980625	0.030305856128573	0.292159721589388
GO:0030983	mismatched DNA binding	4/1659	14/18639	0.285714285714286	3.21002324980625	0.030305856128573	0.292159721589388
GO:0019903	protein phosphatase binding	20/1659	144/18639	0.138888888888889	1.56042796865582	0.0304821539378977	0.292159721589388
GO:0042826	histone deacetylase binding	18/1659	127/18639	0.141732283464567	1.59237373809287	0.0324178872858302	0.307092226561041
GO:0044325	transmembrane transporter binding	19/1659	136/18639	0.139705882352941	1.56960695670673	0.0325330448684249	0.307092226561041
GO:0051020	GTPase binding	38/1659	315/18639	0.120634920634921	1.3553431499182	0.0335753043449546	0.312392771417913
GO:0046625	sphingolipid binding	6/1659	28/18639	0.214285714285714	2.40751743735469	0.0337799619542062	0.312392771417913
GO:0048156	tau protein binding	8/1659	43/18639	0.186046511627907	2.09024769754826	0.03384672884544	0.312392771417913
GO:0004386	helicase activity	21/1659	155/18639	0.135483870967742	1.52217231523071	0.0344315978650011	0.315454198086701
GO:0000287	magnesium ion binding	29/1659	230/18639	0.126086956521739	1.41659721676232	0.0354617719874861	0.322520933550421
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	10/1659	60/18639	0.166666666666667	1.87251356238698	0.0379013289945171	0.332493612068364
GO:0004129	cytochrome-c oxidase activity	4/1659	15/18639	0.266666666666667	2.99602169981917	0.0384891982585604	0.332493612068364
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	4/1659	15/18639	0.266666666666667	2.99602169981917	0.0384891982585604	0.332493612068364
GO:0031386	protein tag activity	4/1659	15/18639	0.266666666666667	2.99602169981917	0.0384891982585604	0.332493612068364
GO:0042809	nuclear vitamin D receptor binding	4/1659	15/18639	0.266666666666667	2.99602169981917	0.0384891982585604	0.332493612068364
GO:0055105	ubiquitin-protein transferase inhibitor activity	4/1659	15/18639	0.266666666666667	2.99602169981917	0.0384891982585604	0.332493612068364
GO:0141047	molecular tag activity	4/1659	15/18639	0.266666666666667	2.99602169981917	0.0384891982585604	0.332493612068364
GO:0022804	active transmembrane transporter activity	52/1659	457/18639	0.113785557986871	1.27839000320512	0.0393960523874388	0.332493612068364
GO:0005200	structural constituent of cytoskeleton	16/1659	112/18639	0.142857142857143	1.60501162490313	0.0394101740449547	0.332493612068364
GO:0140767	enzyme-substrate adaptor activity	19/1659	139/18639	0.136690647482014	1.53573054756918	0.039483996348688	0.332493612068364
GO:0016417	S-acyltransferase activity	6/1659	29/18639	0.206896551724138	2.32449959468729	0.0394936232633369	0.332493612068364
GO:0050660	flavin adenine dinucleotide binding	13/1659	86/18639	0.151162790697674	1.69832625425796	0.0403212979418154	0.337183471379208
GO:0140035	ubiquitin-like protein reader activity	5/1659	22/18639	0.227272727272727	2.55342758507315	0.0406738725971774	0.33786430170722
GO:0140658	ATP-dependent chromatin remodeler activity	21/1659	158/18639	0.132911392405063	1.49327030924531	0.041170945780499	0.339728466506634
GO:0004713	protein tyrosine kinase activity	19/1659	140/18639	0.135714285714286	1.52476104365797	0.04202530372346	0.34246950956485
GO:0030695	GTPase regulator activity	55/1659	489/18639	0.112474437627812	1.26365945927956	0.0420528370492953	0.34246950956485
GO:0051018	protein kinase A binding	9/1659	53/18639	0.169811320754717	1.90784400696032	0.0427957301760047	0.345337161007208
GO:0005201	extracellular matrix structural constituent	22/1659	168/18639	0.130952380952381	1.4712606561612	0.0429592776533846	0.345337161007208
GO:0060589	nucleoside-triphosphatase regulator activity	55/1659	490/18639	0.112244897959184	1.26108056242388	0.0434166376259193	0.346776477448048
GO:0001965	G-protein alpha-subunit binding	6/1659	30/18639	0.2	2.24701627486438	0.0457843945550909	0.354586175664327
GO:0048019	receptor antagonist activity	6/1659	30/18639	0.2	2.24701627486438	0.0457843945550909	0.354586175664327
GO:0003689	DNA clamp loader activity	21/1659	160/18639	0.13125	1.47460443037975	0.0461697018399393	0.354586175664327
GO:0061134	peptidase regulator activity	28/1659	226/18639	0.123893805309735	1.39195698442926	0.0461983444897388	0.354586175664327
GO:0000510	H3-H4 histone complex chaperone activity	20/1659	151/18639	0.132450331125828	1.48809024825455	0.0468607980683881	0.354586175664327
GO:0140584	chromatin extrusion motor activity	20/1659	151/18639	0.132450331125828	1.48809024825455	0.0468607980683881	0.354586175664327
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	20/1659	151/18639	0.132450331125828	1.48809024825455	0.0468607980683881	0.354586175664327
GO:0140849	ATP-dependent H2AZ histone chaperone activity	20/1659	151/18639	0.132450331125828	1.48809024825455	0.0468607980683881	0.354586175664327
GO:0051287	NAD binding	9/1659	54/18639	0.166666666666667	1.87251356238698	0.0474642112808501	0.354586175664327
GO:0140463	chromatin-protein adaptor activity	9/1659	54/18639	0.166666666666667	1.87251356238698	0.0474642112808501	0.354586175664327
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/1659	16/18639	0.25	2.80877034358047	0.0478093719996846	0.354586175664327
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	4/1659	16/18639	0.25	2.80877034358047	0.0478093719996846	0.354586175664327
GO:0004602	glutathione peroxidase activity	5/1659	23/18639	0.217391304347826	2.4424089944178	0.0482940869692152	0.35606172996238
GO:0015616	DNA translocase activity	20/1659	152/18639	0.131578947368421	1.47830018083183	0.049635269364479	0.359235604157046
GO:0140674	ATP-dependent histone chaperone activity	20/1659	152/18639	0.131578947368421	1.47830018083183	0.049635269364479	0.359235604157046
GO:0051015	actin filament binding	26/1659	209/18639	0.124401913875598	1.39766562551373	0.0510088343781677	0.359235604157046
GO:0008374	O-acyltransferase activity	9/1659	55/18639	0.163636363636364	1.83846786125267	0.0524580460535984	0.359235604157046
GO:0005381	iron ion transmembrane transporter activity	3/1659	10/18639	0.3	3.37052441229656	0.0525065965600393	0.359235604157046
GO:0008140	cAMP response element binding protein binding	3/1659	10/18639	0.3	3.37052441229656	0.0525065965600393	0.359235604157046
GO:0016175	superoxide-generating NAD(P)H oxidase activity	3/1659	10/18639	0.3	3.37052441229656	0.0525065965600393	0.359235604157046
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	3/1659	10/18639	0.3	3.37052441229656	0.0525065965600393	0.359235604157046
GO:0050815	phosphoserine residue binding	3/1659	10/18639	0.3	3.37052441229656	0.0525065965600393	0.359235604157046
GO:0097177	mitochondrial ribosome binding	3/1659	10/18639	0.3	3.37052441229656	0.0525065965600393	0.359235604157046
GO:0061775	cohesin loader activity	20/1659	153/18639	0.130718954248366	1.46863808814665	0.0525249782655004	0.359235604157046
GO:0016411	acylglycerol O-acyltransferase activity	6/1659	31/18639	0.193548387096774	2.17453187890101	0.0526627642486571	0.359235604157046
GO:0140457	protein demethylase activity	6/1659	31/18639	0.193548387096774	2.17453187890101	0.0526627642486571	0.359235604157046
GO:0005518	collagen binding	11/1659	72/18639	0.152777777777778	1.7164707655214	0.0527609274163238	0.359235604157046
GO:0001784	phosphotyrosine residue binding	8/1659	47/18639	0.170212765957447	1.91235427648032	0.0537462275734962	0.360041933099872
GO:0061749	forked DNA-dependent helicase activity	8/1659	47/18639	0.170212765957447	1.91235427648032	0.0537462275734962	0.360041933099872
GO:1990518	single-stranded 3'-5' DNA helicase activity	8/1659	47/18639	0.170212765957447	1.91235427648032	0.0537462275734962	0.360041933099872
GO:0030215	semaphorin receptor binding	5/1659	24/18639	0.208333333333333	2.34064195298373	0.0566989784946308	0.370744223780807
GO:0050431	transforming growth factor beta binding	5/1659	24/18639	0.208333333333333	2.34064195298373	0.0566989784946308	0.370744223780807
GO:0070300	phosphatidic acid binding	5/1659	24/18639	0.208333333333333	2.34064195298373	0.0566989784946308	0.370744223780807
GO:0002020	protease binding	18/1659	136/18639	0.132352941176471	1.48699606424848	0.0574230801951941	0.370744223780807
GO:0030169	low-density lipoprotein particle binding	4/1659	17/18639	0.235294117647059	2.64354855866397	0.0582609448216719	0.370744223780807
GO:0030548	acetylcholine receptor regulator activity	4/1659	17/18639	0.235294117647059	2.64354855866397	0.0582609448216719	0.370744223780807
GO:0038191	neuropilin binding	4/1659	17/18639	0.235294117647059	2.64354855866397	0.0582609448216719	0.370744223780807
GO:0048038	quinone binding	4/1659	17/18639	0.235294117647059	2.64354855866397	0.0582609448216719	0.370744223780807
GO:0003823	antigen binding	22/1659	174/18639	0.126436781609195	1.42052753008667	0.0591676188362708	0.370744223780807
GO:0009378	four-way junction helicase activity	8/1659	48/18639	0.166666666666667	1.87251356238698	0.0596834597105905	0.370744223780807
GO:0036121	double-stranded DNA helicase activity	8/1659	48/18639	0.166666666666667	1.87251356238698	0.0596834597105905	0.370744223780807
GO:0043138	3'-5' DNA helicase activity	8/1659	48/18639	0.166666666666667	1.87251356238698	0.0596834597105905	0.370744223780807
GO:0071813	lipoprotein particle binding	6/1659	32/18639	0.1875	2.10657775768535	0.0601353680559256	0.370744223780807
GO:0071814	protein-lipid complex binding	6/1659	32/18639	0.1875	2.10657775768535	0.0601353680559256	0.370744223780807
GO:0120015	sterol transfer activity	6/1659	32/18639	0.1875	2.10657775768535	0.0601353680559256	0.370744223780807
GO:0120013	lipid transfer activity	10/1659	65/18639	0.153846153846154	1.72847405758798	0.0604808029983665	0.370744223780807
GO:0050997	quaternary ammonium group binding	7/1659	40/18639	0.175	1.96613924050633	0.0606996963493455	0.370744223780807
GO:0071949	FAD binding	7/1659	40/18639	0.175	1.96613924050633	0.0606996963493455	0.370744223780807
GO:0008135	translation factor activity, RNA binding	12/1659	83/18639	0.144578313253012	1.62434911435979	0.0631546509454599	0.382808270900245
GO:0061659	ubiquitin-like protein ligase activity	42/1659	372/18639	0.112903225806452	1.26847692935892	0.0650076420121094	0.382808270900245
GO:0003707	nuclear steroid receptor activity	5/1659	25/18639	0.2	2.24701627486438	0.0658886877718313	0.382808270900245
GO:0017025	TBP-class protein binding	5/1659	25/18639	0.2	2.24701627486438	0.0658886877718313	0.382808270900245
GO:0017056	structural constituent of nuclear pore	5/1659	25/18639	0.2	2.24701627486438	0.0658886877718313	0.382808270900245
GO:0001851	complement component C3b binding	3/1659	11/18639	0.272727272727273	3.06411310208779	0.0675513207806253	0.382808270900245
GO:0015217	ADP transmembrane transporter activity	3/1659	11/18639	0.272727272727273	3.06411310208779	0.0675513207806253	0.382808270900245
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	3/1659	11/18639	0.272727272727273	3.06411310208779	0.0675513207806253	0.382808270900245
GO:0019107	myristoyltransferase activity	3/1659	11/18639	0.272727272727273	3.06411310208779	0.0675513207806253	0.382808270900245
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	3/1659	11/18639	0.272727272727273	3.06411310208779	0.0675513207806253	0.382808270900245
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/1659	11/18639	0.272727272727273	3.06411310208779	0.0675513207806253	0.382808270900245
GO:0043522	leucine zipper domain binding	3/1659	11/18639	0.272727272727273	3.06411310208779	0.0675513207806253	0.382808270900245
GO:0048185	activin binding	3/1659	11/18639	0.272727272727273	3.06411310208779	0.0675513207806253	0.382808270900245
GO:0140031	phosphorylation-dependent protein binding	3/1659	11/18639	0.272727272727273	3.06411310208779	0.0675513207806253	0.382808270900245
GO:0042287	MHC protein binding	7/1659	41/18639	0.170731707317073	1.91818462488422	0.0678263314201548	0.382808270900245
GO:0180051	translation factor activity	12/1659	84/18639	0.142857142857143	1.60501162490313	0.0679928812146202	0.382808270900245
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	6/1659	33/18639	0.181818181818182	2.04274206805852	0.0682050049276519	0.382808270900245
GO:0030296	protein tyrosine kinase activator activity	6/1659	33/18639	0.181818181818182	2.04274206805852	0.0682050049276519	0.382808270900245
GO:0017116	single-stranded DNA helicase activity	9/1659	58/18639	0.155172413793103	1.74337469601546	0.0694443073882016	0.386562955768588
GO:0017075	syntaxin-1 binding	4/1659	18/18639	0.222222222222222	2.49668474984931	0.0698242310008502	0.386562955768588
GO:0030228	lipoprotein particle receptor activity	4/1659	18/18639	0.222222222222222	2.49668474984931	0.0698242310008502	0.386562955768588
GO:0008234	cysteine-type peptidase activity	23/1659	187/18639	0.122994652406417	1.38185492839253	0.0701149502437407	0.386562955768588
GO:0042562	hormone binding	13/1659	94/18639	0.138297872340426	1.55378784964026	0.0729535092982423	0.400440848394757
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	16/1659	122/18639	0.131147540983607	1.47345329499303	0.0748940919466527	0.407402801681832
GO:0001786	phosphatidylserine binding	9/1659	59/18639	0.152542372881356	1.71382597235419	0.075786659155161	0.407402801681832
GO:0031593	polyubiquitin modification-dependent protein binding	9/1659	59/18639	0.152542372881356	1.71382597235419	0.075786659155161	0.407402801681832
GO:0005160	transforming growth factor beta receptor binding	5/1659	26/18639	0.192307692307692	2.16059257198498	0.0758567014367456	0.407402801681832
GO:0019865	immunoglobulin binding	5/1659	26/18639	0.192307692307692	2.16059257198498	0.0758567014367456	0.407402801681832
GO:0140098	catalytic activity, acting on RNA	43/1659	387/18639	0.111111111111111	1.24834237492465	0.0763384727796213	0.408230631259262
GO:0003724	RNA helicase activity	11/1659	77/18639	0.142857142857143	1.60501162490313	0.0782812815136142	0.41519208555351
GO:0005010	insulin-like growth factor receptor activity	8/1659	51/18639	0.156862745098039	1.76236570577598	0.0798837598814499	0.41519208555351
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	27/1659	229/18639	0.117903930131004	1.3246602493742	0.0805374088405138	0.41519208555351
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	4/1659	19/18639	0.210526315789474	2.36528028933092	0.0824669062588452	0.41519208555351
GO:0050145	nucleoside monophosphate kinase activity	4/1659	19/18639	0.210526315789474	2.36528028933092	0.0824669062588452	0.41519208555351
GO:1990380	K48-linked deubiquitinase activity	4/1659	19/18639	0.210526315789474	2.36528028933092	0.0824669062588452	0.41519208555351
GO:0008094	ATP-dependent activity, acting on DNA	25/1659	210/18639	0.119047619047619	1.33750968741927	0.0824714799418249	0.41519208555351
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	9/1659	60/18639	0.15	1.68526220614828	0.0824723056540983	0.41519208555351
GO:0004896	cytokine receptor activity	13/1659	96/18639	0.135416666666667	1.52141726943942	0.0832026504086516	0.41519208555351
GO:0019199	transmembrane receptor protein kinase activity	11/1659	78/18639	0.141025641025641	1.58443455278898	0.0841750223147933	0.41519208555351
GO:0000995	RNA polymerase III general transcription initiation factor activity	3/1659	12/18639	0.25	2.80877034358047	0.0843046530056486	0.41519208555351
GO:0003995	acyl-CoA dehydrogenase activity	3/1659	12/18639	0.25	2.80877034358047	0.0843046530056486	0.41519208555351
GO:0005165	neurotrophin receptor binding	3/1659	12/18639	0.25	2.80877034358047	0.0843046530056486	0.41519208555351
GO:0016273	arginine N-methyltransferase activity	3/1659	12/18639	0.25	2.80877034358047	0.0843046530056486	0.41519208555351
GO:0016274	protein-arginine N-methyltransferase activity	3/1659	12/18639	0.25	2.80877034358047	0.0843046530056486	0.41519208555351
GO:0016423	tRNA (guanine) methyltransferase activity	3/1659	12/18639	0.25	2.80877034358047	0.0843046530056486	0.41519208555351
GO:0017166	vinculin binding	3/1659	12/18639	0.25	2.80877034358047	0.0843046530056486	0.41519208555351
GO:0035259	nuclear glucocorticoid receptor binding	3/1659	12/18639	0.25	2.80877034358047	0.0843046530056486	0.41519208555351
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/1659	12/18639	0.25	2.80877034358047	0.0843046530056486	0.41519208555351
GO:0097371	MDM2/MDM4 family protein binding	3/1659	12/18639	0.25	2.80877034358047	0.0843046530056486	0.41519208555351
GO:0035401	histone H3Y41 kinase activity	15/1659	115/18639	0.130434782608696	1.46544539665068	0.0856815917008304	0.418663777487195
GO:0140801	histone H2AXY142 kinase activity	15/1659	115/18639	0.130434782608696	1.46544539665068	0.0856815917008304	0.418663777487195
GO:0140566	histone reader activity	6/1659	35/18639	0.171428571428571	1.92601394988375	0.0861278153409725	0.41920022622989
GO:0015252	proton channel activity	5/1659	27/18639	0.185185185185185	2.08057062487442	0.0865902457760525	0.41981107485199
GO:0008013	beta-catenin binding	14/1659	106/18639	0.132075471698113	1.48387867208025	0.0872787101616617	0.421508809540428
GO:0015026	coreceptor activity	9/1659	61/18639	0.147540983606557	1.65763495686716	0.0895014147959647	0.43057437388329
GO:0008186	ATP-dependent activity, acting on RNA	11/1659	79/18639	0.139240506329114	1.56437841920938	0.0903352391651837	0.432914261537765
GO:0001223	transcription coactivator binding	7/1659	44/18639	0.159090909090909	1.78739930955121	0.0920820452650074	0.43959474482835
GO:0061630	ubiquitin protein ligase activity	39/1659	353/18639	0.110481586402266	1.24126961359364	0.0935039123791985	0.444678911543822
GO:0061135	endopeptidase regulator activity	22/1659	184/18639	0.119565217391304	1.34332494692979	0.0949230859742907	0.44534387531287
GO:0016860	intramolecular oxidoreductase activity	8/1659	53/18639	0.150943396226415	1.69586133952028	0.0953507815476936	0.44534387531287
GO:1990782	protein tyrosine kinase binding	15/1659	117/18639	0.128205128205128	1.44039504798998	0.0959471055776234	0.44534387531287
GO:0004869	cysteine-type endopeptidase inhibitor activity	6/1659	36/18639	0.166666666666667	1.87251356238698	0.0959681850914011	0.44534387531287
GO:0000339	RNA cap binding	4/1659	20/18639	0.2	2.24701627486438	0.0961456681052665	0.44534387531287
GO:0031418	L-ascorbic acid binding	4/1659	20/18639	0.2	2.24701627486438	0.0961456681052665	0.44534387531287
GO:0140939	histone H4 methyltransferase activity	4/1659	20/18639	0.2	2.24701627486438	0.0961456681052665	0.44534387531287
GO:0045499	chemorepellent activity	5/1659	28/18639	0.178571428571429	2.00626453112891	0.0980707422590624	0.452578314277007
GO:0004519	endonuclease activity	16/1659	127/18639	0.125984251968504	1.41544332274921	0.0987393878190235	0.453982572776765
GO:0008009	chemokine activity	7/1659	45/18639	0.155555555555556	1.74767932489451	0.101115900114381	0.458301762842569
GO:0051539	4 iron, 4 sulfur cluster binding	7/1659	45/18639	0.155555555555556	1.74767932489451	0.101115900114381	0.458301762842569
GO:0019787	ubiquitin-like protein transferase activity	51/1659	479/18639	0.106471816283925	1.19621952002175	0.102573679766478	0.458301762842569
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	3/1659	13/18639	0.230769230769231	2.59271108638197	0.102621341760094	0.458301762842569
GO:0008035	high-density lipoprotein particle binding	3/1659	13/18639	0.230769230769231	2.59271108638197	0.102621341760094	0.458301762842569
GO:0039706	co-receptor binding	3/1659	13/18639	0.230769230769231	2.59271108638197	0.102621341760094	0.458301762842569
GO:0043560	insulin receptor substrate binding	3/1659	13/18639	0.230769230769231	2.59271108638197	0.102621341760094	0.458301762842569
GO:0051011	microtubule minus-end binding	3/1659	13/18639	0.230769230769231	2.59271108638197	0.102621341760094	0.458301762842569
GO:0030971	receptor tyrosine kinase binding	11/1659	81/18639	0.135802469135802	1.52575179157458	0.103454626205587	0.459729129476057
GO:0050661	NADP binding	8/1659	54/18639	0.148148148148148	1.66445649989954	0.103678880724536	0.459729129476057
GO:1901682	sulfur compound transmembrane transporter activity	9/1659	63/18639	0.142857142857143	1.60501162490313	0.104584934611654	0.462102228816033
GO:0004842	ubiquitin-protein transferase activity	48/1659	449/18639	0.106904231625835	1.20107774157561	0.105103013136955	0.462750368793801
GO:0008017	microtubule binding	31/1659	276/18639	0.11231884057971	1.26191131378253	0.105678946946462	0.463647774279195
GO:0043236	laminin binding	5/1659	29/18639	0.172413793103448	1.93708299557274	0.110274308716505	0.47445577451152
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/1659	29/18639	0.172413793103448	1.93708299557274	0.110274308716505	0.47445577451152
GO:0004180	carboxypeptidase activity	7/1659	46/18639	0.152173913043478	1.70968629609246	0.11061347804635	0.47445577451152
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	4/1659	21/18639	0.19047619047619	2.14001549987083	0.110807889552851	0.47445577451152
GO:0035613	RNA stem-loop binding	4/1659	21/18639	0.19047619047619	2.14001549987083	0.110807889552851	0.47445577451152
GO:0051010	microtubule plus-end binding	4/1659	21/18639	0.19047619047619	2.14001549987083	0.110807889552851	0.47445577451152
GO:0072542	protein phosphatase activator activity	4/1659	21/18639	0.19047619047619	2.14001549987083	0.110807889552851	0.47445577451152
GO:0003697	single-stranded DNA binding	15/1659	121/18639	0.12396694214876	1.39277868276718	0.118676066621213	0.506405407568599
GO:0016755	aminoacyltransferase activity	52/1659	496/18639	0.104838709677419	1.17787143440471	0.121306066436954	0.506510479438251
GO:0016853	isomerase activity	21/1659	180/18639	0.116666666666667	1.31075949367089	0.121439363067768	0.506510479438251
GO:0004065	arylsulfatase activity	3/1659	14/18639	0.214285714285714	2.40751743735469	0.122343746932327	0.506510479438251
GO:0005347	ATP transmembrane transporter activity	3/1659	14/18639	0.214285714285714	2.40751743735469	0.122343746932327	0.506510479438251
GO:0008174	mRNA methyltransferase activity	3/1659	14/18639	0.214285714285714	2.40751743735469	0.122343746932327	0.506510479438251
GO:0031404	chloride ion binding	3/1659	14/18639	0.214285714285714	2.40751743735469	0.122343746932327	0.506510479438251
GO:0034236	protein kinase A catalytic subunit binding	3/1659	14/18639	0.214285714285714	2.40751743735469	0.122343746932327	0.506510479438251
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	3/1659	14/18639	0.214285714285714	2.40751743735469	0.122343746932327	0.506510479438251
GO:0005085	guanyl-nucleotide exchange factor activity	26/1659	230/18639	0.11304347826087	1.27005267709726	0.122471347832827	0.506510479438251
GO:0032452	histone demethylase activity	5/1659	30/18639	0.166666666666667	1.87251356238698	0.123172291548788	0.506510479438251
GO:0070566	adenylyltransferase activity	5/1659	30/18639	0.166666666666667	1.87251356238698	0.123172291548788	0.506510479438251
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	15/1659	122/18639	0.122950819672131	1.38136246405597	0.124813726622319	0.51111140108598
GO:0004860	protein kinase inhibitor activity	11/1659	84/18639	0.130952380952381	1.4712606561612	0.125111538789104	0.51111140108598
GO:0046972	histone H4K16 acetyltransferase activity	4/1659	22/18639	0.181818181818182	2.04274206805852	0.126393226654112	0.512983584400727
GO:0050321	tau-protein kinase activity	4/1659	22/18639	0.181818181818182	2.04274206805852	0.126393226654112	0.512983584400727
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	16/1659	132/18639	0.121212121212121	1.36182804537235	0.126821983962573	0.513052571484955
GO:0000217	DNA secondary structure binding	6/1659	39/18639	0.153846153846154	1.72847405758798	0.12885822195714	0.514606873585244
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	6/1659	39/18639	0.153846153846154	1.72847405758798	0.12885822195714	0.514606873585244
GO:0016776	phosphotransferase activity, phosphate group as acceptor	6/1659	39/18639	0.153846153846154	1.72847405758798	0.12885822195714	0.514606873585244
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/1659	39/18639	0.153846153846154	1.72847405758798	0.12885822195714	0.514606873585244
GO:0046906	tetrapyrrole binding	18/1659	152/18639	0.118421052631579	1.33047016274864	0.12962728014398	0.51602425258594
GO:0015631	tubulin binding	41/1659	385/18639	0.106493506493506	1.19646321129142	0.130908214610981	0.518018362349938
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	7/1659	48/18639	0.145833333333333	1.63844936708861	0.130959698346894	0.518018362349938
GO:0140034	methylation-dependent protein binding	10/1659	76/18639	0.131578947368421	1.47830018083183	0.136008312633219	0.529854601155956
GO:0005164	tumor necrosis factor receptor binding	5/1659	31/18639	0.161290322580645	1.81210989908417	0.136731816029583	0.529854601155956
GO:0061791	GTPase motor activity	6/1659	40/18639	0.15	1.68526220614828	0.140886197064397	0.529854601155956
GO:1990606	membrane scission GTPase motor activity	6/1659	40/18639	0.15	1.68526220614828	0.140886197064397	0.529854601155956
GO:0005004	GPI-linked ephrin receptor activity	7/1659	49/18639	0.142857142857143	1.60501162490313	0.141783467968937	0.529854601155956
GO:0005008	hepatocyte growth factor receptor activity	7/1659	49/18639	0.142857142857143	1.60501162490313	0.141783467968937	0.529854601155956
GO:0005009	insulin receptor activity	7/1659	49/18639	0.142857142857143	1.60501162490313	0.141783467968937	0.529854601155956
GO:0005011	macrophage colony-stimulating factor receptor activity	7/1659	49/18639	0.142857142857143	1.60501162490313	0.141783467968937	0.529854601155956
GO:0005018	platelet-derived growth factor alpha-receptor activity	7/1659	49/18639	0.142857142857143	1.60501162490313	0.141783467968937	0.529854601155956
GO:0005020	stem cell factor receptor activity	7/1659	49/18639	0.142857142857143	1.60501162490313	0.141783467968937	0.529854601155956
GO:0008288	boss receptor activity	7/1659	49/18639	0.142857142857143	1.60501162490313	0.141783467968937	0.529854601155956
GO:0036332	placental growth factor receptor activity	7/1659	49/18639	0.142857142857143	1.60501162490313	0.141783467968937	0.529854601155956
GO:0038062	protein tyrosine kinase collagen receptor activity	7/1659	49/18639	0.142857142857143	1.60501162490313	0.141783467968937	0.529854601155956
GO:0060175	brain-derived neurotrophic factor receptor activity	7/1659	49/18639	0.142857142857143	1.60501162490313	0.141783467968937	0.529854601155956
GO:0005158	insulin receptor binding	4/1659	23/18639	0.173913043478261	1.95392719553424	0.142835150798301	0.529854601155956
GO:0042171	lysophosphatidic acid acyltransferase activity	4/1659	23/18639	0.173913043478261	1.95392719553424	0.142835150798301	0.529854601155956
GO:0071617	lysophospholipid acyltransferase activity	4/1659	23/18639	0.173913043478261	1.95392719553424	0.142835150798301	0.529854601155956
GO:0005041	low-density lipoprotein particle receptor activity	3/1659	15/18639	0.2	2.24701627486438	0.143307384100768	0.529854601155956
GO:0033130	acetylcholine receptor binding	3/1659	15/18639	0.2	2.24701627486438	0.143307384100768	0.529854601155956
GO:0045504	dynein heavy chain binding	3/1659	15/18639	0.2	2.24701627486438	0.143307384100768	0.529854601155956
GO:0061578	K63-linked deubiquitinase activity	3/1659	15/18639	0.2	2.24701627486438	0.143307384100768	0.529854601155956
GO:0120283	protein serine/threonine kinase binding	3/1659	15/18639	0.2	2.24701627486438	0.143307384100768	0.529854601155956
GO:1901981	phosphatidylinositol phosphate binding	21/1659	185/18639	0.113513513513514	1.27533356140951	0.147895704635318	0.54433630137549
GO:1990841	promoter-specific chromatin binding	9/1659	68/18639	0.132352941176471	1.48699606424848	0.148097918271502	0.54433630137549
GO:0051059	NF-kappaB binding	5/1659	32/18639	0.15625	1.75548146473779	0.150916343432112	0.547707131357735
GO:0140142	nucleocytoplasmic carrier activity	5/1659	32/18639	0.15625	1.75548146473779	0.150916343432112	0.547707131357735
GO:0015459	potassium channel regulator activity	8/1659	59/18639	0.135593220338983	1.52340086431483	0.151025491347924	0.547707131357735
GO:0005006	epidermal growth factor receptor activity	7/1659	50/18639	0.14	1.57291139240506	0.15302146474521	0.547707131357735
GO:0005007	fibroblast growth factor receptor activity	7/1659	50/18639	0.14	1.57291139240506	0.15302146474521	0.547707131357735
GO:0005017	platelet-derived growth factor receptor activity	7/1659	50/18639	0.14	1.57291139240506	0.15302146474521	0.547707131357735
GO:0005019	platelet-derived growth factor beta-receptor activity	7/1659	50/18639	0.14	1.57291139240506	0.15302146474521	0.547707131357735
GO:0001727	lipid kinase activity	6/1659	41/18639	0.146341463414634	1.64415824990076	0.153410745460553	0.547707131357735
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	6/1659	41/18639	0.146341463414634	1.64415824990076	0.153410745460553	0.547707131357735
GO:0042169	SH2 domain binding	6/1659	41/18639	0.146341463414634	1.64415824990076	0.153410745460553	0.547707131357735
GO:0005516	calmodulin binding	23/1659	207/18639	0.111111111111111	1.24834237492465	0.158189416098744	0.56038687187659
GO:0031406	carboxylic acid binding	21/1659	187/18639	0.112299465240642	1.26169363027144	0.159325068105894	0.56038687187659
GO:0043998	histone H2A acetyltransferase activity	4/1659	24/18639	0.166666666666667	1.87251356238698	0.160062385259035	0.56038687187659
GO:0048027	mRNA 5'-UTR binding	4/1659	24/18639	0.166666666666667	1.87251356238698	0.160062385259035	0.56038687187659
GO:0004714	transmembrane receptor protein tyrosine kinase activity	8/1659	60/18639	0.133333333333333	1.49801084990958	0.161572135300821	0.56038687187659
GO:0033293	monocarboxylic acid binding	10/1659	79/18639	0.126582278481013	1.42216219928125	0.162670210755612	0.56038687187659
GO:0005021	vascular endothelial growth factor receptor activity	7/1659	51/18639	0.137254901960784	1.54206999255398	0.164657008700808	0.56038687187659
GO:0005030	neurotrophin receptor activity	7/1659	51/18639	0.137254901960784	1.54206999255398	0.164657008700808	0.56038687187659
GO:0003688	DNA replication origin binding	3/1659	16/18639	0.1875	2.10657775768535	0.165345386893326	0.56038687187659
GO:0005024	transforming growth factor beta receptor activity	3/1659	16/18639	0.1875	2.10657775768535	0.165345386893326	0.56038687187659
GO:0005159	insulin-like growth factor receptor binding	3/1659	16/18639	0.1875	2.10657775768535	0.165345386893326	0.56038687187659
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/1659	16/18639	0.1875	2.10657775768535	0.165345386893326	0.56038687187659
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/1659	16/18639	0.1875	2.10657775768535	0.165345386893326	0.56038687187659
GO:0030275	LRR domain binding	3/1659	16/18639	0.1875	2.10657775768535	0.165345386893326	0.56038687187659
GO:0097027	ubiquitin-protein transferase activator activity	3/1659	16/18639	0.1875	2.10657775768535	0.165345386893326	0.56038687187659
GO:0005319	lipid transporter activity	20/1659	178/18639	0.112359550561798	1.26236869374403	0.165759192556346	0.56038687187659
GO:0008307	structural constituent of muscle	6/1659	42/18639	0.142857142857143	1.60501162490313	0.166407016528361	0.56038687187659
GO:0016859	cis-trans isomerase activity	6/1659	42/18639	0.142857142857143	1.60501162490313	0.166407016528361	0.56038687187659
GO:0031492	nucleosomal DNA binding	6/1659	42/18639	0.142857142857143	1.60501162490313	0.166407016528361	0.56038687187659
GO:0035198	miRNA binding	6/1659	42/18639	0.142857142857143	1.60501162490313	0.166407016528361	0.56038687187659
GO:0042056	chemoattractant activity	6/1659	42/18639	0.142857142857143	1.60501162490313	0.166407016528361	0.56038687187659
GO:0043177	organic acid binding	21/1659	189/18639	0.111111111111111	1.24834237492465	0.171224500862959	0.575055870822769
GO:0035591	signaling adaptor activity	15/1659	129/18639	0.116279069767442	1.30640481096766	0.17270835208398	0.5784801255286
GO:0019210	kinase inhibitor activity	11/1659	90/18639	0.122222222222222	1.37317661241712	0.175221584114977	0.585324648276839
GO:0000030	mannosyltransferase activity	4/1659	25/18639	0.16	1.7976130198915	0.178000232399454	0.586741506798201
GO:0001848	complement binding	4/1659	25/18639	0.16	1.7976130198915	0.178000232399454	0.586741506798201
GO:0008139	nuclear localization sequence binding	4/1659	25/18639	0.16	1.7976130198915	0.178000232399454	0.586741506798201
GO:0019211	phosphatase activator activity	4/1659	25/18639	0.16	1.7976130198915	0.178000232399454	0.586741506798201
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	4/1659	25/18639	0.16	1.7976130198915	0.178000232399454	0.586741506798201
GO:0019825	oxygen binding	5/1659	34/18639	0.147058823529412	1.65221784916498	0.180999246764521	0.59505293263481
GO:0005539	glycosaminoglycan binding	26/1659	242/18639	0.107438016528926	1.20707485839822	0.182337693431727	0.597875700041925
GO:0072341	modified amino acid binding	11/1659	91/18639	0.120879120879121	1.35808675953341	0.184394443765596	0.59937019181362
GO:0004659	prenyltransferase activity	3/1659	17/18639	0.176470588235294	1.98266141899798	0.188292053051537	0.59937019181362
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/1659	17/18639	0.176470588235294	1.98266141899798	0.188292053051537	0.59937019181362
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/1659	17/18639	0.176470588235294	1.98266141899798	0.188292053051537	0.59937019181362
GO:0005092	GDP-dissociation inhibitor activity	3/1659	17/18639	0.176470588235294	1.98266141899798	0.188292053051537	0.59937019181362
GO:0008484	sulfuric ester hydrolase activity	3/1659	17/18639	0.176470588235294	1.98266141899798	0.188292053051537	0.59937019181362
GO:0019198	transmembrane receptor protein phosphatase activity	3/1659	17/18639	0.176470588235294	1.98266141899798	0.188292053051537	0.59937019181362
GO:0046965	nuclear retinoid X receptor binding	3/1659	17/18639	0.176470588235294	1.98266141899798	0.188292053051537	0.59937019181362
GO:0070403	NAD+ binding	3/1659	17/18639	0.176470588235294	1.98266141899798	0.188292053051537	0.59937019181362
GO:0005003	ephrin receptor activity	7/1659	53/18639	0.132075471698113	1.48387867208025	0.189046938509432	0.59937019181362
GO:0005005	transmembrane-ephrin receptor activity	7/1659	53/18639	0.132075471698113	1.48387867208025	0.189046938509432	0.59937019181362
GO:0017046	peptide hormone binding	7/1659	53/18639	0.132075471698113	1.48387867208025	0.189046938509432	0.59937019181362
GO:0038064	collagen receptor activity	7/1659	53/18639	0.132075471698113	1.48387867208025	0.189046938509432	0.59937019181362
GO:0019205	nucleobase-containing compound kinase activity	6/1659	44/18639	0.136363636363636	1.53205655104389	0.193706080911777	0.606996770777764
GO:0043178	alcohol binding	11/1659	92/18639	0.119565217391304	1.34332494692979	0.193784122634628	0.606996770777764
GO:0005507	copper ion binding	8/1659	63/18639	0.126984126984127	1.42667699991389	0.195147436100422	0.606996770777764
GO:0020037	heme binding	16/1659	142/18639	0.112676056338028	1.26592466189542	0.195231311383421	0.606996770777764
GO:0008157	protein phosphatase 1 binding	4/1659	26/18639	0.153846153846154	1.72847405758798	0.196571783483583	0.606996770777764
GO:0008198	ferrous iron binding	4/1659	26/18639	0.153846153846154	1.72847405758798	0.196571783483583	0.606996770777764
GO:0030507	spectrin binding	4/1659	26/18639	0.153846153846154	1.72847405758798	0.196571783483583	0.606996770777764
GO:0052742	phosphatidylinositol kinase activity	4/1659	26/18639	0.153846153846154	1.72847405758798	0.196571783483583	0.606996770777764
GO:0120014	phospholipid transfer activity	4/1659	26/18639	0.153846153846154	1.72847405758798	0.196571783483583	0.606996770777764
GO:0004674	protein serine/threonine kinase activity	44/1659	433/18639	0.10161662817552	1.14167108653617	0.19666315142226	0.606996770777764
GO:0043015	gamma-tubulin binding	5/1659	35/18639	0.142857142857143	1.60501162490313	0.196811152001779	0.606996770777764
GO:0043539	protein serine/threonine kinase activator activity	9/1659	73/18639	0.123287671232877	1.38514701875201	0.199189842654673	0.612816157895611
GO:0015485	cholesterol binding	7/1659	54/18639	0.12962962962963	1.4563994374121	0.201761330094417	0.619198564772521
GO:0051213	dioxygenase activity	11/1659	93/18639	0.118279569892473	1.32888059266173	0.203382814458508	0.619224341243669
GO:0141110	transporter inhibitor activity	6/1659	45/18639	0.133333333333333	1.49801084990958	0.207950724111377	0.619224341243669
GO:0003678	DNA helicase activity	9/1659	74/18639	0.121621621621622	1.3664288157959	0.210207049351592	0.619224341243669
GO:0035064	methylated histone binding	9/1659	74/18639	0.121621621621622	1.3664288157959	0.210207049351592	0.619224341243669
GO:0000400	four-way junction DNA binding	3/1659	18/18639	0.166666666666667	1.87251356238698	0.211985617461675	0.619224341243669
GO:0003746	translation elongation factor activity	3/1659	18/18639	0.166666666666667	1.87251356238698	0.211985617461675	0.619224341243669
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	3/1659	18/18639	0.166666666666667	1.87251356238698	0.211985617461675	0.619224341243669
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/1659	18/18639	0.166666666666667	1.87251356238698	0.211985617461675	0.619224341243669
GO:1990381	ubiquitin-specific protease binding	3/1659	18/18639	0.166666666666667	1.87251356238698	0.211985617461675	0.619224341243669
GO:0004033	aldo-keto reductase (NADPH) activity	5/1659	36/18639	0.138888888888889	1.56042796865582	0.213076146664743	0.619224341243669
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	5/1659	36/18639	0.138888888888889	1.56042796865582	0.213076146664743	0.619224341243669
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	5/1659	36/18639	0.138888888888889	1.56042796865582	0.213076146664743	0.619224341243669
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	5/1659	36/18639	0.138888888888889	1.56042796865582	0.213076146664743	0.619224341243669
GO:0004683	calcium/calmodulin-dependent protein kinase activity	4/1659	27/18639	0.148148148148148	1.66445649989954	0.215699007432719	0.619224341243669
GO:0005044	scavenger receptor activity	4/1659	27/18639	0.148148148148148	1.66445649989954	0.215699007432719	0.619224341243669
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/1659	27/18639	0.148148148148148	1.66445649989954	0.215699007432719	0.619224341243669
GO:0035255	ionotropic glutamate receptor binding	4/1659	27/18639	0.148148148148148	1.66445649989954	0.215699007432719	0.619224341243669
GO:0016887	ATP hydrolysis activity	42/1659	417/18639	0.100719424460432	1.13159092978782	0.219992618834776	0.619224341243669
GO:0044183	protein folding chaperone	9/1659	75/18639	0.12	1.34820976491863	0.221461811729967	0.619224341243669
GO:0001094	TFIID-class transcription factor complex binding	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0004090	carbonyl reductase (NADPH) activity	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0004955	prostaglandin receptor activity	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0005131	growth hormone receptor binding	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0005345	purine nucleobase transmembrane transporter activity	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0016427	tRNA (cytidine) methyltransferase activity	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0016783	sulfurtransferase activity	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0031419	cobalamin binding	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0031996	thioesterase binding	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0032356	oxidized DNA binding	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0042975	peroxisome proliferator activated receptor binding	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0043121	neurotrophin binding	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0043208	glycosphingolipid binding	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0140940	histone H2A methyltransferase activity	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:1990259	histone H2AQ104 methyltransferase activity	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:1990757	ubiquitin ligase activator activity	2/1659	10/18639	0.2	2.24701627486438	0.221648520220447	0.619224341243669
GO:0030291	protein serine/threonine kinase inhibitor activity	6/1659	46/18639	0.130434782608696	1.46544539665068	0.22255131102113	0.620355556000735
GO:0043021	ribonucleoprotein complex binding	19/1659	177/18639	0.107344632768362	1.20602568424924	0.228040120382526	0.634236584813901
GO:0005096	GTPase activator activity	28/1659	271/18639	0.103321033210332	1.16082021579709	0.229695442255731	0.636144947658349
GO:0043394	proteoglycan binding	5/1659	37/18639	0.135135135135135	1.51825423977323	0.229747372749805	0.636144947658349
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	10/1659	86/18639	0.116279069767442	1.30640481096766	0.233517041088641	0.641378841529429
GO:0004518	nuclease activity	22/1659	209/18639	0.105263157894737	1.18264014466546	0.234419014390606	0.641378841529429
GO:0019789	SUMO transferase activity	4/1659	28/18639	0.142857142857143	1.60501162490313	0.235303718294995	0.641378841529429
GO:0046875	ephrin receptor binding	4/1659	28/18639	0.142857142857143	1.60501162490313	0.235303718294995	0.641378841529429
GO:0141052	histone H3 demethylase activity	4/1659	28/18639	0.142857142857143	1.60501162490313	0.235303718294995	0.641378841529429
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/1659	19/18639	0.157894736842105	1.77396021699819	0.236270375812205	0.641378841529429
GO:0015245	fatty acid transmembrane transporter activity	3/1659	19/18639	0.157894736842105	1.77396021699819	0.236270375812205	0.641378841529429
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/1659	19/18639	0.157894736842105	1.77396021699819	0.236270375812205	0.641378841529429
GO:0046624	sphingolipid transporter activity	3/1659	19/18639	0.157894736842105	1.77396021699819	0.236270375812205	0.641378841529429
GO:0061733	protein-lysine-acetyltransferase activity	6/1659	47/18639	0.127659574468085	1.43426570736024	0.237476100895574	0.641855144719924
GO:0140938	histone H3 methyltransferase activity	6/1659	47/18639	0.127659574468085	1.43426570736024	0.237476100895574	0.641855144719924
GO:0016500	protein-hormone receptor activity	8/1659	67/18639	0.119402985074627	1.34150225365037	0.243856378876377	0.653893088619882
GO:0051540	metal cluster binding	9/1659	77/18639	0.116883116883117	1.31319132946619	0.244629568979445	0.653893088619882
GO:0000146	microfilament motor activity	5/1659	38/18639	0.131578947368421	1.47830018083183	0.246777352857053	0.653893088619882
GO:0042887	amide transmembrane transporter activity	5/1659	38/18639	0.131578947368421	1.47830018083183	0.246777352857053	0.653893088619882
GO:0043531	ADP binding	5/1659	38/18639	0.131578947368421	1.47830018083183	0.246777352857053	0.653893088619882
GO:1901681	sulfur compound binding	28/1659	275/18639	0.101818181818182	1.14393555811277	0.254126235883172	0.653893088619882
GO:0004181	metallocarboxypeptidase activity	4/1659	29/18639	0.137931034482759	1.54966639645819	0.255308423827553	0.653893088619882
GO:0004629	phospholipase C activity	4/1659	29/18639	0.137931034482759	1.54966639645819	0.255308423827553	0.653893088619882
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	4/1659	29/18639	0.137931034482759	1.54966639645819	0.255308423827553	0.653893088619882
GO:0097472	cyclin-dependent protein kinase activity	4/1659	29/18639	0.137931034482759	1.54966639645819	0.255308423827553	0.653893088619882
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0002162	dystroglycan binding	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0004954	prostanoid receptor activity	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0005114	type II transforming growth factor beta receptor binding	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0008199	ferric iron binding	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0008271	secondary active sulfate transmembrane transporter activity	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0008526	phosphatidylinositol transfer activity	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0015205	nucleobase transmembrane transporter activity	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0032050	clathrin heavy chain binding	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0034713	type I transforming growth factor beta receptor binding	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0050998	nitric-oxide synthase binding	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0070697	activin receptor binding	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0097493	structural molecule activity conferring elasticity	2/1659	11/18639	0.181818181818182	2.04274206805852	0.255892342318185	0.653893088619882
GO:0005548	phospholipid transporter activity	8/1659	68/18639	0.117647058823529	1.32177427933199	0.256624173623694	0.653893088619882
GO:0032934	sterol binding	8/1659	68/18639	0.117647058823529	1.32177427933199	0.256624173623694	0.653893088619882
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	3/1659	20/18639	0.15	1.68526220614828	0.260998265407548	0.659642674843416
GO:0016004	phospholipase activator activity	3/1659	20/18639	0.15	1.68526220614828	0.260998265407548	0.659642674843416
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/1659	20/18639	0.15	1.68526220614828	0.260998265407548	0.659642674843416
GO:0061608	nuclear import signal receptor activity	3/1659	20/18639	0.15	1.68526220614828	0.260998265407548	0.659642674843416
GO:0016798	hydrolase activity, acting on glycosyl bonds	14/1659	130/18639	0.107692307692308	1.20993184031159	0.266587065395203	0.672403812717456
GO:0001222	transcription corepressor binding	6/1659	49/18639	0.122448979591837	1.37572424991696	0.268168440788611	0.673665075045583
GO:0035254	glutamate receptor binding	6/1659	49/18639	0.122448979591837	1.37572424991696	0.268168440788611	0.673665075045583
GO:0004879	nuclear receptor activity	7/1659	59/18639	0.11864406779661	1.33297575627548	0.2696433149828	0.674091743930914
GO:0070063	RNA polymerase binding	7/1659	59/18639	0.11864406779661	1.33297575627548	0.2696433149828	0.674091743930914
GO:0008201	heparin binding	18/1659	172/18639	0.104651162790698	1.17576432987089	0.269961300338303	0.674091743930914
GO:0008106	alcohol dehydrogenase (NADP+) activity	4/1659	30/18639	0.133333333333333	1.49801084990958	0.275637059562748	0.67970208779162
GO:0015215	nucleotide transmembrane transporter activity	4/1659	30/18639	0.133333333333333	1.49801084990958	0.275637059562748	0.67970208779162
GO:0043995	histone H4K5 acetyltransferase activity	4/1659	30/18639	0.133333333333333	1.49801084990958	0.275637059562748	0.67970208779162
GO:0043996	histone H4K8 acetyltransferase activity	4/1659	30/18639	0.133333333333333	1.49801084990958	0.275637059562748	0.67970208779162
GO:0043997	histone H4K12 acetyltransferase activity	4/1659	30/18639	0.133333333333333	1.49801084990958	0.275637059562748	0.67970208779162
GO:0141003	histone H2AX kinase activity	35/1659	354/18639	0.0988700564971751	1.11081313022956	0.280749638883565	0.67970208779162
GO:0008028	monocarboxylic acid transmembrane transporter activity	8/1659	70/18639	0.114285714285714	1.2840092999225	0.282740408143341	0.67970208779162
GO:1902936	phosphatidylinositol bisphosphate binding	12/1659	111/18639	0.108108108108108	1.21460339181858	0.283134493328346	0.67970208779162
GO:0098531	ligand-modulated transcription factor activity	7/1659	60/18639	0.116666666666667	1.31075949367089	0.283916867016269	0.67970208779162
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/1659	21/18639	0.142857142857143	1.60501162490313	0.286029994716664	0.67970208779162
GO:0001846	opsonin binding	3/1659	21/18639	0.142857142857143	1.60501162490313	0.286029994716664	0.67970208779162
GO:0030246	carbohydrate binding	28/1659	280/18639	0.1	1.12350813743219	0.286100032236999	0.67970208779162
GO:0003774	cytoskeletal motor activity	16/1659	153/18639	0.104575163398693	1.17491047051732	0.286464142799986	0.67970208779162
GO:0004875	complement receptor activity	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0005025	transforming growth factor beta receptor activity, type I	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0005026	transforming growth factor beta receptor activity, type II	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0005049	nuclear export signal receptor activity	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0005078	MAP-kinase scaffold activity	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0005095	GTPase inhibitor activity	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0016208	AMP binding	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0016361	activin receptor activity, type I	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0016362	activin receptor activity, type II	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0017002	activin receptor activity	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0036009	protein-glutamine N-methyltransferase activity	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0045295	gamma-catenin binding	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:1990459	transferrin receptor binding	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:1990817	poly(A) RNA polymerase activity	2/1659	12/18639	0.166666666666667	1.87251356238698	0.290209880180692	0.67970208779162
GO:0004721	phosphoprotein phosphatase activity	18/1659	175/18639	0.102857142857143	1.15560836993025	0.294812444310653	0.689186314467305
GO:0072349	modified amino acid transmembrane transporter activity	4/1659	31/18639	0.129032258064516	1.44968791926734	0.296215614160254	0.691169766373925
GO:0008238	exopeptidase activity	11/1659	102/18639	0.107843137254902	1.21162642272099	0.297695435529228	0.692298437377155
GO:0140996	histone H3 kinase activity	35/1659	357/18639	0.0980392156862745	1.10147856610999	0.29824241721738	0.692298437377155
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	7/1659	61/18639	0.114754098360656	1.2892716331189	0.298366180474745	0.692298437377155
GO:0003743	translation initiation factor activity	6/1659	51/18639	0.117647058823529	1.32177427933199	0.299765406819146	0.694252224714975
GO:0051087	protein-folding chaperone binding	14/1659	134/18639	0.104477611940299	1.17381447194408	0.304871097336721	0.696229456103195
GO:0008093	cytoskeletal anchor activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0015377	chloride:monoatomic cation symporter activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0032931	histone H3K56 acetyltransferase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0034062	5'-3' RNA polymerase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0043992	histone H3K9 acetyltransferase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0043993	histone H3K18 acetyltransferase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0043994	histone H3K23 acetyltransferase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0043999	histone H2AK5 acetyltransferase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0044012	histone H2AK9 acetyltransferase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0044014	histone H2BK5 acetyltransferase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0044015	histone H2BK12 acetyltransferase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0044016	histone H3K4 acetyltransferase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0044017	histone H3K27 acetyltransferase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0044018	histone H3K36 acetyltransferase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0097747	RNA polymerase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0140908	histone H3K122 acetyltransferase activity	3/1659	22/18639	0.136363636363636	1.53205655104389	0.311235800200224	0.696229456103195
GO:0005080	protein kinase C binding	6/1659	52/18639	0.115384615384615	1.29635554319099	0.31582107191959	0.704004950190164
GO:0035173	histone kinase activity	35/1659	360/18639	0.0972222222222222	1.09229957805907	0.316109473391317	0.704004950190164
GO:0004402	histone acetyltransferase activity	5/1659	42/18639	0.119047619047619	1.33750968741927	0.317535653295304	0.704004950190164
GO:0048487	beta-tubulin binding	5/1659	42/18639	0.119047619047619	1.33750968741927	0.317535653295304	0.704004950190164
GO:0004521	RNA endonuclease activity	8/1659	73/18639	0.10958904109589	1.23124179444623	0.323081701852122	0.704004950190164
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/1659	13/18639	0.153846153846154	1.72847405758798	0.324316887166255	0.704004950190164
GO:0008253	5'-nucleotidase activity	2/1659	13/18639	0.153846153846154	1.72847405758798	0.324316887166255	0.704004950190164
GO:0009982	pseudouridine synthase activity	2/1659	13/18639	0.153846153846154	1.72847405758798	0.324316887166255	0.704004950190164
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/1659	13/18639	0.153846153846154	1.72847405758798	0.324316887166255	0.704004950190164
GO:0017154	semaphorin receptor activity	2/1659	13/18639	0.153846153846154	1.72847405758798	0.324316887166255	0.704004950190164
GO:0019855	calcium channel inhibitor activity	2/1659	13/18639	0.153846153846154	1.72847405758798	0.324316887166255	0.704004950190164
GO:0031994	insulin-like growth factor I binding	2/1659	13/18639	0.153846153846154	1.72847405758798	0.324316887166255	0.704004950190164
GO:0035325	Toll-like receptor binding	2/1659	13/18639	0.153846153846154	1.72847405758798	0.324316887166255	0.704004950190164
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/1659	13/18639	0.153846153846154	1.72847405758798	0.324316887166255	0.704004950190164
GO:0070123	transforming growth factor beta receptor activity, type III	2/1659	13/18639	0.153846153846154	1.72847405758798	0.324316887166255	0.704004950190164
GO:0097157	pre-mRNA intronic binding	2/1659	13/18639	0.153846153846154	1.72847405758798	0.324316887166255	0.704004950190164
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/1659	13/18639	0.153846153846154	1.72847405758798	0.324316887166255	0.704004950190164
GO:0001664	G protein-coupled receptor binding	29/1659	297/18639	0.0976430976430976	1.09702814766106	0.327665782788071	0.710037504963368
GO:0034212	protein N-acetyltransferase activity	6/1659	53/18639	0.113207547169811	1.27189600464021	0.332005003844291	0.718191379843727
GO:0042578	phosphoric ester hydrolase activity	35/1659	363/18639	0.0964187327823691	1.08327230881891	0.334310010632412	0.720401870142094
GO:0008200	ion channel inhibitor activity	5/1659	43/18639	0.116279069767442	1.30640481096766	0.335652415851393	0.720401870142094
GO:0000295	adenine nucleotide transmembrane transporter activity	3/1659	23/18639	0.130434782608696	1.46544539665068	0.336495897610513	0.720401870142094
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/1659	23/18639	0.130434782608696	1.46544539665068	0.336495897610513	0.720401870142094
GO:0008171	O-methyltransferase activity	3/1659	23/18639	0.130434782608696	1.46544539665068	0.336495897610513	0.720401870142094
GO:0044013	histone H2B acetyltransferase activity	3/1659	23/18639	0.130434782608696	1.46544539665068	0.336495897610513	0.720401870142094
GO:0071889	14-3-3 protein binding	4/1659	33/18639	0.121212121212121	1.36182804537235	0.337839746287813	0.722038291380128
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	6/1659	54/18639	0.111111111111111	1.24834237492465	0.348285463063025	0.738818120690594
GO:0016407	acetyltransferase activity	10/1659	96/18639	0.104166666666667	1.17032097649186	0.349715170410533	0.738818120690594
GO:0019003	GDP binding	8/1659	75/18639	0.106666666666667	1.19840867992767	0.3505308410391	0.738818120690594
GO:0001046	core promoter sequence-specific DNA binding	5/1659	44/18639	0.113636363636364	1.27671379253658	0.353850663920574	0.738818120690594
GO:0016248	channel inhibitor activity	5/1659	44/18639	0.113636363636364	1.27671379253658	0.353850663920574	0.738818120690594
GO:0005161	platelet-derived growth factor receptor binding	2/1659	14/18639	0.142857142857143	1.60501162490313	0.357979077205243	0.738818120690594
GO:0005545	1-phosphatidylinositol binding	2/1659	14/18639	0.142857142857143	1.60501162490313	0.357979077205243	0.738818120690594
GO:0015926	glucosidase activity	2/1659	14/18639	0.142857142857143	1.60501162490313	0.357979077205243	0.738818120690594
GO:0019992	diacylglycerol binding	2/1659	14/18639	0.142857142857143	1.60501162490313	0.357979077205243	0.738818120690594
GO:0032036	myosin heavy chain binding	2/1659	14/18639	0.142857142857143	1.60501162490313	0.357979077205243	0.738818120690594
GO:0042043	neurexin family protein binding	2/1659	14/18639	0.142857142857143	1.60501162490313	0.357979077205243	0.738818120690594
GO:0046030	inositol trisphosphate phosphatase activity	2/1659	14/18639	0.142857142857143	1.60501162490313	0.357979077205243	0.738818120690594
GO:0061665	SUMO ligase activity	2/1659	14/18639	0.142857142857143	1.60501162490313	0.357979077205243	0.738818120690594
GO:0070742	C2H2 zinc finger domain binding	2/1659	14/18639	0.142857142857143	1.60501162490313	0.357979077205243	0.738818120690594
GO:0071933	Arp2/3 complex binding	2/1659	14/18639	0.142857142857143	1.60501162490313	0.357979077205243	0.738818120690594
GO:0098821	BMP receptor activity	2/1659	14/18639	0.142857142857143	1.60501162490313	0.357979077205243	0.738818120690594
GO:0008175	tRNA methyltransferase activity	4/1659	34/18639	0.117647058823529	1.32177427933199	0.358751812890918	0.738818120690594
GO:0015035	protein-disulfide reductase activity	4/1659	34/18639	0.117647058823529	1.32177427933199	0.358751812890918	0.738818120690594
GO:0052866	phosphatidylinositol phosphate phosphatase activity	4/1659	34/18639	0.117647058823529	1.32177427933199	0.358751812890918	0.738818120690594
GO:0090482	vitamin transmembrane transporter activity	4/1659	34/18639	0.117647058823529	1.32177427933199	0.358751812890918	0.738818120690594
GO:0004866	endopeptidase inhibitor activity	16/1659	161/18639	0.0993788819875776	1.11652982601957	0.359991311959353	0.738818120690594
GO:0001091	RNA polymerase II general transcription initiation factor binding	3/1659	24/18639	0.125	1.40438517179024	0.361700685089296	0.738818120690594
GO:0050699	WW domain binding	3/1659	24/18639	0.125	1.40438517179024	0.361700685089296	0.738818120690594
GO:0060229	lipase activator activity	3/1659	24/18639	0.125	1.40438517179024	0.361700685089296	0.738818120690594
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/1659	24/18639	0.125	1.40438517179024	0.361700685089296	0.738818120690594
GO:0070840	dynein complex binding	3/1659	24/18639	0.125	1.40438517179024	0.361700685089296	0.738818120690594
GO:0140612	DNA damage sensor activity	3/1659	24/18639	0.125	1.40438517179024	0.361700685089296	0.738818120690594
GO:0051536	iron-sulfur cluster binding	8/1659	76/18639	0.105263157894737	1.18264014466546	0.364364982341718	0.742370480480416
GO:0098632	cell-cell adhesion mediator activity	6/1659	55/18639	0.109090909090909	1.22564524083511	0.364631407748005	0.742370480480416
GO:0008081	phosphoric diester hydrolase activity	9/1659	87/18639	0.103448275862069	1.16224979734364	0.369790198460225	0.751645329986037
GO:0004715	non-membrane spanning protein tyrosine kinase activity	5/1659	45/18639	0.111111111111111	1.24834237492465	0.372088156396724	0.753856655073688
GO:0140303	intramembrane lipid transporter activity	5/1659	45/18639	0.111111111111111	1.24834237492465	0.372088156396724	0.753856655073688
GO:0005154	epidermal growth factor receptor binding	4/1659	35/18639	0.114285714285714	1.2840092999225	0.379647382037904	0.762858048226358
GO:0010485	histone H4 acetyltransferase activity	4/1659	35/18639	0.114285714285714	1.2840092999225	0.379647382037904	0.762858048226358
GO:0019212	phosphatase inhibitor activity	6/1659	56/18639	0.107142857142857	1.20375871867734	0.381012623224088	0.762858048226358
GO:0015271	outward rectifier potassium channel activity	3/1659	25/18639	0.12	1.34820976491863	0.386750746819729	0.762858048226358
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/1659	25/18639	0.12	1.34820976491863	0.386750746819729	0.762858048226358
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/1659	25/18639	0.12	1.34820976491863	0.386750746819729	0.762858048226358
GO:0042054	histone methyltransferase activity	7/1659	67/18639	0.104477611940299	1.17381447194408	0.387393596822604	0.762858048226358
GO:0016791	phosphatase activity	26/1659	273/18639	0.0952380952380952	1.07000774993542	0.388334567804297	0.762858048226358
GO:0000774	adenyl-nucleotide exchange factor activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0004559	alpha-mannosidase activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0004953	icosanoid receptor activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0008252	nucleotidase activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0015116	sulfate transmembrane transporter activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0015929	hexosaminidase activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0017081	chloride channel regulator activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0140161	monocarboxylate:sodium symporter activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0141050	histone H3K deacetylase activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0141051	histone H4K deacetylase activity	2/1659	15/18639	0.133333333333333	1.49801084990958	0.391005491529009	0.762858048226358
GO:0004540	RNA nuclease activity	12/1659	121/18639	0.0991735537190083	1.11422294621374	0.391753030750958	0.762858048226358
GO:0016758	hexosyltransferase activity	19/1659	197/18639	0.0964467005076142	1.0835865284879	0.391837199731035	0.762858048226358
GO:0015932	nucleobase-containing compound transmembrane transporter activity	6/1659	57/18639	0.105263157894737	1.18264014466546	0.397399836467233	0.772480805363763
GO:0005484	SNAP receptor activity	4/1659	36/18639	0.111111111111111	1.24834237492465	0.400468786459549	0.776025051210882
GO:0044390	ubiquitin-like protein conjugating enzyme binding	4/1659	36/18639	0.111111111111111	1.24834237492465	0.400468786459549	0.776025051210882
GO:0004435	phosphatidylinositol phospholipase C activity	3/1659	26/18639	0.115384615384615	1.29635554319099	0.411556698559225	0.787104986672085
GO:0004529	DNA exonuclease activity	3/1659	26/18639	0.115384615384615	1.29635554319099	0.411556698559225	0.787104986672085
GO:0015216	purine nucleotide transmembrane transporter activity	3/1659	26/18639	0.115384615384615	1.29635554319099	0.411556698559225	0.787104986672085
GO:0030247	polysaccharide binding	3/1659	26/18639	0.115384615384615	1.29635554319099	0.411556698559225	0.787104986672085
GO:0034237	protein kinase A regulatory subunit binding	3/1659	26/18639	0.115384615384615	1.29635554319099	0.411556698559225	0.787104986672085
GO:0050681	nuclear androgen receptor binding	3/1659	26/18639	0.115384615384615	1.29635554319099	0.411556698559225	0.787104986672085
GO:0051139	metal cation:proton antiporter activity	3/1659	26/18639	0.115384615384615	1.29635554319099	0.411556698559225	0.787104986672085
GO:0097602	cullin family protein binding	3/1659	26/18639	0.115384615384615	1.29635554319099	0.411556698559225	0.787104986672085
GO:0043022	ribosome binding	11/1659	112/18639	0.0982142857142857	1.1034454921209	0.412728595339295	0.787104986672085
GO:0061980	regulatory RNA binding	6/1659	58/18639	0.103448275862069	1.16224979734364	0.41376481599727	0.787104986672085
GO:0016874	ligase activity	16/1659	167/18639	0.0958083832335329	1.07641498197096	0.417150243095284	0.787104986672085
GO:0008080	N-acetyltransferase activity	7/1659	69/18639	0.101449275362319	1.13979086406164	0.417394391214297	0.787104986672085
GO:0048306	calcium-dependent protein binding	8/1659	80/18639	0.1	1.12350813743219	0.42000337700675	0.787104986672085
GO:0000062	fatty-acyl-CoA binding	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0004707	MAP kinase activity	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0005149	interleukin-1 receptor binding	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0005521	lamin binding	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0008142	oxysterol binding	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0015923	mannosidase activity	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0022841	potassium ion leak channel activity	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0022858	alanine transmembrane transporter activity	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0055102	lipase inhibitor activity	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0070411	I-SMAD binding	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	2/1659	16/18639	0.125	1.40438517179024	0.423242649334106	0.787104986672085
GO:0015297	antiporter activity	13/1659	135/18639	0.0962962962962963	1.0818967249347	0.42582903638443	0.789734450919009
GO:0032266	phosphatidylinositol-3-phosphate binding	5/1659	48/18639	0.104166666666667	1.17032097649186	0.426640095254975	0.789734450919009
GO:0140693	molecular condensate scaffold activity	5/1659	48/18639	0.104166666666667	1.17032097649186	0.426640095254975	0.789734450919009
GO:0019001	guanyl nucleotide binding	37/1659	400/18639	0.0925	1.03924502712477	0.427825645562064	0.789734450919009
GO:0032561	guanyl ribonucleotide binding	37/1659	400/18639	0.0925	1.03924502712477	0.427825645562064	0.789734450919009
GO:0005525	GTP binding	35/1659	378/18639	0.0925925925925926	1.04028531243721	0.428785451680403	0.790335314783701
GO:0052689	carboxylic ester hydrolase activity	9/1659	92/18639	0.0978260869565217	1.09908404748801	0.434955128573322	0.797534447922578
GO:0008320	protein transmembrane transporter activity	3/1659	27/18639	0.111111111111111	1.24834237492465	0.436038909950039	0.797534447922578
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	3/1659	27/18639	0.111111111111111	1.24834237492465	0.436038909950039	0.797534447922578
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	3/1659	27/18639	0.111111111111111	1.24834237492465	0.436038909950039	0.797534447922578
GO:0030414	peptidase inhibitor activity	16/1659	169/18639	0.0946745562130177	1.06367634313107	0.436338587869271	0.797534447922578
GO:0016779	nucleotidyltransferase activity	13/1659	136/18639	0.0955882352941176	1.07394160195724	0.436531696214445	0.797534447922578
GO:0005109	frizzled binding	4/1659	38/18639	0.105263157894737	1.18264014466546	0.44167816624512	0.805755483369574
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	17/1659	181/18639	0.0939226519337017	1.05522863736725	0.445435705797237	0.80948440654411
GO:0141108	transporter regulator activity	16/1659	170/18639	0.0941176470588235	1.05741942346559	0.445932445429708	0.80948440654411
GO:0001098	basal transcription machinery binding	6/1659	60/18639	0.1	1.12350813743219	0.446320856577692	0.80948440654411
GO:0001099	basal RNA polymerase II transcription machinery binding	6/1659	60/18639	0.1	1.12350813743219	0.446320856577692	0.80948440654411
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/1659	17/18639	0.117647058823529	1.32177427933199	0.454569395505116	0.816128914696505
GO:0004550	nucleoside diphosphate kinase activity	2/1659	17/18639	0.117647058823529	1.32177427933199	0.454569395505116	0.816128914696505
GO:0015278	intracellularly gated calcium channel activity	2/1659	17/18639	0.117647058823529	1.32177427933199	0.454569395505116	0.816128914696505
GO:0017110	nucleoside diphosphate phosphatase activity	2/1659	17/18639	0.117647058823529	1.32177427933199	0.454569395505116	0.816128914696505
GO:0032183	SUMO binding	2/1659	17/18639	0.117647058823529	1.32177427933199	0.454569395505116	0.816128914696505
GO:0051787	misfolded protein binding	2/1659	17/18639	0.117647058823529	1.32177427933199	0.454569395505116	0.816128914696505
GO:1901567	fatty acid derivative binding	2/1659	17/18639	0.117647058823529	1.32177427933199	0.454569395505116	0.816128914696505
GO:0099106	ion channel regulator activity	15/1659	160/18639	0.09375	1.05328887884268	0.456314099577877	0.816275519018608
GO:0019783	ubiquitin-like protein peptidase activity	12/1659	127/18639	0.094488188976378	1.06158249206191	0.458690423652305	0.816275519018608
GO:0016866	intramolecular transferase activity	3/1659	28/18639	0.107142857142857	1.20375871867734	0.460127132948644	0.816275519018608
GO:0036408	histone H3K14 acetyltransferase activity	3/1659	28/18639	0.107142857142857	1.20375871867734	0.460127132948644	0.816275519018608
GO:0051019	mitogen-activated protein kinase binding	3/1659	28/18639	0.107142857142857	1.20375871867734	0.460127132948644	0.816275519018608
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/1659	28/18639	0.107142857142857	1.20375871867734	0.460127132948644	0.816275519018608
GO:0016410	N-acyltransferase activity	9/1659	94/18639	0.0957446808510638	1.07569928052018	0.460918846676962	0.816275519018608
GO:0042379	chemokine receptor binding	7/1659	72/18639	0.0972222222222222	1.09229957805907	0.46209996436994	0.816275519018608
GO:0019905	syntaxin binding	6/1659	61/18639	0.0983606557377049	1.10508997124478	0.462461366698014	0.816275519018608
GO:0015605	organophosphate ester transmembrane transporter activity	5/1659	50/18639	0.1	1.12350813743219	0.462512452991282	0.816275519018608
GO:0032813	tumor necrosis factor receptor superfamily binding	5/1659	50/18639	0.1	1.12350813743219	0.462512452991282	0.816275519018608
GO:0048020	CCR chemokine receptor binding	5/1659	50/18639	0.1	1.12350813743219	0.462512452991282	0.816275519018608
GO:0031490	chromatin DNA binding	12/1659	128/18639	0.09375	1.05328887884268	0.469796126563712	0.827957529983572
GO:0019208	phosphatase regulator activity	11/1659	117/18639	0.094017094017094	1.05628970185932	0.471082392053715	0.829051780365718
GO:0000149	SNARE binding	10/1659	106/18639	0.0943396226415094	1.05991333720018	0.472423087702977	0.830238599827798
GO:0015036	disulfide oxidoreductase activity	4/1659	40/18639	0.1	1.12350813743219	0.481998233966394	0.833346055489159
GO:0071855	neuropeptide receptor binding	4/1659	40/18639	0.1	1.12350813743219	0.481998233966394	0.833346055489159
GO:0003785	actin monomer binding	3/1659	29/18639	0.103448275862069	1.16224979734364	0.483760060924155	0.833346055489159
GO:0010484	histone H3 acetyltransferase activity	3/1659	29/18639	0.103448275862069	1.16224979734364	0.483760060924155	0.833346055489159
GO:0000900	mRNA regulatory element binding translation repressor activity	2/1659	18/18639	0.111111111111111	1.24834237492465	0.484892367760546	0.833346055489159
GO:0008409	5'-3' exonuclease activity	2/1659	18/18639	0.111111111111111	1.24834237492465	0.484892367760546	0.833346055489159
GO:0008525	phosphatidylcholine transporter activity	2/1659	18/18639	0.111111111111111	1.24834237492465	0.484892367760546	0.833346055489159
GO:0015172	acidic amino acid transmembrane transporter activity	2/1659	18/18639	0.111111111111111	1.24834237492465	0.484892367760546	0.833346055489159
GO:0017128	phospholipid scramblase activity	2/1659	18/18639	0.111111111111111	1.24834237492465	0.484892367760546	0.833346055489159
GO:0034185	apolipoprotein binding	2/1659	18/18639	0.111111111111111	1.24834237492465	0.484892367760546	0.833346055489159
GO:0050811	GABA receptor binding	2/1659	18/18639	0.111111111111111	1.24834237492465	0.484892367760546	0.833346055489159
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/1659	18/18639	0.111111111111111	1.24834237492465	0.484892367760546	0.833346055489159
GO:0070064	proline-rich region binding	2/1659	18/18639	0.111111111111111	1.24834237492465	0.484892367760546	0.833346055489159
GO:0070628	proteasome binding	2/1659	18/18639	0.111111111111111	1.24834237492465	0.484892367760546	0.833346055489159
GO:0098641	cadherin binding involved in cell-cell adhesion	2/1659	18/18639	0.111111111111111	1.24834237492465	0.484892367760546	0.833346055489159
GO:1901611	phosphatidylglycerol binding	2/1659	18/18639	0.111111111111111	1.24834237492465	0.484892367760546	0.833346055489159
GO:0003924	GTPase activity	30/1659	331/18639	0.0906344410876133	1.01828532093552	0.486686784280112	0.83527786943942
GO:0048029	monosaccharide binding	7/1659	74/18639	0.0945945945945946	1.06277796784126	0.49147963798537	0.842343368541638
GO:0005496	steroid binding	10/1659	108/18639	0.0925925925925926	1.04028531243721	0.496674313323684	0.850077190111689
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	5/1659	52/18639	0.0961538461538462	1.08029628599249	0.497689719249952	0.850539942717355
GO:0001530	lipopolysaccharide binding	4/1659	41/18639	0.0975609756097561	1.09610549993384	0.501722999917541	0.850539942717355
GO:0004812	aminoacyl-tRNA ligase activity	4/1659	41/18639	0.0975609756097561	1.09610549993384	0.501722999917541	0.850539942717355
GO:0016875	ligase activity, forming carbon-oxygen bonds	4/1659	41/18639	0.0975609756097561	1.09610549993384	0.501722999917541	0.850539942717355
GO:0016877	ligase activity, forming carbon-sulfur bonds	4/1659	41/18639	0.0975609756097561	1.09610549993384	0.501722999917541	0.850539942717355
GO:0017080	sodium channel regulator activity	4/1659	41/18639	0.0975609756097561	1.09610549993384	0.501722999917541	0.850539942717355
GO:0140318	protein transporter activity	4/1659	41/18639	0.0975609756097561	1.09610549993384	0.501722999917541	0.850539942717355
GO:0033612	receptor serine/threonine kinase binding	3/1659	30/18639	0.1	1.12350813743219	0.5068848388532	0.853225911621189
GO:0035925	mRNA 3'-UTR AU-rich region binding	3/1659	30/18639	0.1	1.12350813743219	0.5068848388532	0.853225911621189
GO:0004536	DNA nuclease activity	6/1659	64/18639	0.09375	1.05328887884268	0.510056885244422	0.853225911621189
GO:0016757	glycosyltransferase activity	24/1659	267/18639	0.0898876404494382	1.00989495499523	0.511326754747553	0.853225911621189
GO:0004725	protein tyrosine phosphatase activity	9/1659	98/18639	0.0918367346938776	1.03179318743772	0.512092992538939	0.853225911621189
GO:0005520	insulin-like growth factor binding	2/1659	19/18639	0.105263157894737	1.18264014466546	0.514142013872115	0.853225911621189
GO:0022840	leak channel activity	2/1659	19/18639	0.105263157894737	1.18264014466546	0.514142013872115	0.853225911621189
GO:0022842	narrow pore channel activity	2/1659	19/18639	0.105263157894737	1.18264014466546	0.514142013872115	0.853225911621189
GO:0030506	ankyrin binding	2/1659	19/18639	0.105263157894737	1.18264014466546	0.514142013872115	0.853225911621189
GO:0031420	alkali metal ion binding	2/1659	19/18639	0.105263157894737	1.18264014466546	0.514142013872115	0.853225911621189
GO:0034987	immunoglobulin receptor binding	2/1659	19/18639	0.105263157894737	1.18264014466546	0.514142013872115	0.853225911621189
GO:0042800	histone H3K4 methyltransferase activity	2/1659	19/18639	0.105263157894737	1.18264014466546	0.514142013872115	0.853225911621189
GO:0042834	peptidoglycan binding	2/1659	19/18639	0.105263157894737	1.18264014466546	0.514142013872115	0.853225911621189
GO:0043395	heparan sulfate proteoglycan binding	2/1659	19/18639	0.105263157894737	1.18264014466546	0.514142013872115	0.853225911621189
GO:0120227	acyl-CoA binding	2/1659	19/18639	0.105263157894737	1.18264014466546	0.514142013872115	0.853225911621189
GO:0004864	protein phosphatase inhibitor activity	5/1659	53/18639	0.0943396226415094	1.05991333720018	0.514948543771376	0.853225911621189
GO:1901505	carbohydrate derivative transmembrane transporter activity	5/1659	53/18639	0.0943396226415094	1.05991333720018	0.514948543771376	0.853225911621189
GO:0098631	cell adhesion mediator activity	7/1659	76/18639	0.0921052631578947	1.03481012658228	0.520356734332726	0.86104182068868
GO:0051879	Hsp90 protein binding	4/1659	42/18639	0.0952380952380952	1.07000774993542	0.521111141667249	0.861146528537656
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	15/1659	167/18639	0.0898203592814371	1.00913904559777	0.524930606585495	0.866309318947717
GO:0005310	dicarboxylic acid transmembrane transporter activity	3/1659	31/18639	0.0967741935483871	1.0872659394505	0.529456541498872	0.870320383519255
GO:0008327	methyl-CpG binding	3/1659	31/18639	0.0967741935483871	1.0872659394505	0.529456541498872	0.870320383519255
GO:0047499	calcium-independent phospholipase A2 activity	3/1659	31/18639	0.0967741935483871	1.0872659394505	0.529456541498872	0.870320383519255
GO:0035402	histone H3T11 kinase activity	22/1659	247/18639	0.0890688259109312	1.00069550702462	0.531513041849975	0.872126191842925
GO:0003925	G protein activity	5/1659	54/18639	0.0925925925925926	1.04028531243721	0.531954980578349	0.872126191842925
GO:0016247	channel regulator activity	15/1659	168/18639	0.0892857142857143	1.00313226556445	0.534556876959803	0.873853687139385
GO:0106310	protein serine kinase activity	32/1659	361/18639	0.0886426592797784	0.995907490244599	0.537218442577842	0.873853687139385
GO:0004712	protein serine/threonine/tyrosine kinase activity	4/1659	43/18639	0.0930232558139535	1.04512384877413	0.540132549443235	0.873853687139385
GO:0008235	metalloexopeptidase activity	6/1659	66/18639	0.0909090909090909	1.02137103402926	0.540896031053908	0.873853687139385
GO:0016505	peptidase activator activity involved in apoptotic process	2/1659	20/18639	0.1	1.12350813743219	0.542269097034845	0.873853687139385
GO:0052745	inositol phosphate phosphatase activity	2/1659	20/18639	0.1	1.12350813743219	0.542269097034845	0.873853687139385
GO:0140664	ATP-dependent DNA damage sensor activity	2/1659	20/18639	0.1	1.12350813743219	0.542269097034845	0.873853687139385
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	8/1659	89/18639	0.0898876404494382	1.00989495499523	0.542424901669089	0.873853687139385
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	8/1659	89/18639	0.0898876404494382	1.00989495499523	0.542424901669089	0.873853687139385
GO:0022884	macromolecule transmembrane transporter activity	3/1659	32/18639	0.09375	1.05328887884268	0.551437633429546	0.873853687139385
GO:0047498	calcium-dependent phospholipase A2 activity	3/1659	32/18639	0.09375	1.05328887884268	0.551437633429546	0.873853687139385
GO:0140793	histone H2AXY142 phosphatase activity	8/1659	90/18639	0.0888888888888889	0.998673899939723	0.555453941238076	0.873853687139385
GO:0008173	RNA methyltransferase activity	6/1659	67/18639	0.0895522388059701	1.00612669023778	0.555994631142233	0.873853687139385
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	6/1659	67/18639	0.0895522388059701	1.00612669023778	0.555994631142233	0.873853687139385
GO:0016835	carbon-oxygen lyase activity	7/1659	79/18639	0.0886075949367089	0.995513539496875	0.562464365870086	0.873853687139385
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	8/1659	91/18639	0.0879120879120879	0.987699461478847	0.568324328793346	0.873853687139385
GO:0009931	calcium-dependent protein serine/threonine kinase activity	2/1659	21/18639	0.0952380952380952	1.07000774993542	0.569241634120969	0.873853687139385
GO:0019200	carbohydrate kinase activity	2/1659	21/18639	0.0952380952380952	1.07000774993542	0.569241634120969	0.873853687139385
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/1659	21/18639	0.0952380952380952	1.07000774993542	0.569241634120969	0.873853687139385
GO:0051428	peptide hormone receptor binding	2/1659	21/18639	0.0952380952380952	1.07000774993542	0.569241634120969	0.873853687139385
GO:1904047	S-adenosyl-L-methionine binding	2/1659	21/18639	0.0952380952380952	1.07000774993542	0.569241634120969	0.873853687139385
GO:0140223	general transcription initiation factor activity	6/1659	68/18639	0.0882352941176471	0.991330709498989	0.570858635051971	0.873853687139385
GO:0019956	chemokine binding	3/1659	33/18639	0.0909090909090909	1.02137103402926	0.572797422143719	0.873853687139385
GO:0140416	transcription regulator inhibitor activity	3/1659	33/18639	0.0909090909090909	1.02137103402926	0.572797422143719	0.873853687139385
GO:0004722	protein serine/threonine phosphatase activity	9/1659	103/18639	0.087378640776699	0.981706139503854	0.573715578256684	0.873853687139385
GO:0000049	tRNA binding	7/1659	80/18639	0.0875	0.983069620253164	0.576125008637803	0.873853687139385
GO:0046915	transition metal ion transmembrane transporter activity	4/1659	45/18639	0.0888888888888889	0.998673899939723	0.576972697175869	0.873853687139385
GO:0016279	protein-lysine N-methyltransferase activity	6/1659	69/18639	0.0869565217391304	0.97696359776712	0.585474277322225	0.873853687139385
GO:0070851	growth factor receptor binding	12/1659	139/18639	0.0863309352517986	0.96993508267527	0.587890275965979	0.873853687139385
GO:0140101	catalytic activity, acting on a tRNA	12/1659	139/18639	0.0863309352517986	0.96993508267527	0.587890275965979	0.873853687139385
GO:0015101	organic cation transmembrane transporter activity	7/1659	81/18639	0.0864197530864197	0.97093295827473	0.589578697590277	0.873853687139385
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	21/1659	243/18639	0.0864197530864197	0.97093295827473	0.589861429941854	0.873853687139385
GO:0015020	glucuronosyltransferase activity	3/1659	34/18639	0.0882352941176471	0.991330709498989	0.593511513361732	0.873853687139385
GO:0030332	cyclin binding	3/1659	34/18639	0.0882352941176471	0.991330709498989	0.593511513361732	0.873853687139385
GO:0051427	hormone receptor binding	3/1659	34/18639	0.0882352941176471	0.991330709498989	0.593511513361732	0.873853687139385
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	11/1659	128/18639	0.0859375	0.965514805605787	0.594125442901269	0.873853687139385
GO:0004407	histone deacetylase activity	2/1659	22/18639	0.0909090909090909	1.02137103402926	0.595042217513044	0.873853687139385
GO:0033558	protein lysine deacetylase activity	2/1659	22/18639	0.0909090909090909	1.02137103402926	0.595042217513044	0.873853687139385
GO:0033691	sialic acid binding	2/1659	22/18639	0.0909090909090909	1.02137103402926	0.595042217513044	0.873853687139385
GO:0070034	telomerase RNA binding	2/1659	22/18639	0.0909090909090909	1.02137103402926	0.595042217513044	0.873853687139385
GO:0140517	protein-RNA adaptor activity	2/1659	22/18639	0.0909090909090909	1.02137103402926	0.595042217513044	0.873853687139385
GO:0016278	lysine N-methyltransferase activity	6/1659	70/18639	0.0857142857142857	0.963006974941875	0.599829120987854	0.873853687139385
GO:0016782	transferase activity, transferring sulphur-containing groups	6/1659	70/18639	0.0857142857142857	0.963006974941875	0.599829120987854	0.873853687139385
GO:0004676	3-phosphoinositide-dependent protein kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0004711	ribosomal protein S6 kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0035175	histone H3S10 kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0035979	histone H2AXS139 kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0044022	histone H3S28 kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0044023	histone H4S1 kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0044024	histone H2AS1 kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0044025	histone H2BS14 kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0072354	histone H3T3 kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0072371	histone H2AS121 kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0072518	Rho-dependent protein serine/threonine kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0140823	histone H2BS36 kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0140855	histone H3S57 kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0140995	histone H2A kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0140997	histone H4 kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0140998	histone H2B kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:1990244	histone H2AT120 kinase activity	21/1659	245/18639	0.0857142857142857	0.963006974941875	0.60530605693885	0.873853687139385
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0003796	lysozyme activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0004382	GDP phosphatase activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0005031	tumor necrosis factor receptor activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0005337	nucleoside transmembrane transporter activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0005522	profilin binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0005528	FK506 binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0008401	retinoic acid 4-hydroxylase activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0015187	glycine transmembrane transporter activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0015643	toxic substance binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0016868	intramolecular phosphotransferase activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0019531	oxalate transmembrane transporter activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0030957	Tat protein binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0031434	mitogen-activated protein kinase kinase binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0035374	chondroitin sulfate binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0043295	glutathione binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0051378	serotonin binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0051864	histone H3K36 demethylase activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0051880	G-quadruplex DNA binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0070097	delta-catenin binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0098505	G-rich strand telomeric DNA binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0099122	RNA polymerase II C-terminal domain binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0140999	histone H3K4 trimethyltransferase activity	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:1990763	arrestin family protein binding	1/1659	10/18639	0.1	1.12350813743219	0.606406157047203	0.873853687139385
GO:0043495	protein-membrane adaptor activity	4/1659	47/18639	0.0851063829787234	0.95617713824016	0.612072278549547	0.873853687139385
GO:0036002	pre-mRNA binding	5/1659	59/18639	0.0847457627118644	0.95212554019677	0.612514927153063	0.873853687139385
GO:0004677	DNA-dependent protein kinase activity	21/1659	246/18639	0.0853658536585366	0.959092312442112	0.612936347115211	0.873853687139385
GO:0140857	histone H3T45 kinase activity	21/1659	246/18639	0.0853658536585366	0.959092312442112	0.612936347115211	0.873853687139385
GO:0004623	phospholipase A2 activity	3/1659	35/18639	0.0857142857142857	0.963006974941875	0.613561275673341	0.873853687139385
GO:0061631	ubiquitin conjugating enzyme activity	3/1659	35/18639	0.0857142857142857	0.963006974941875	0.613561275673341	0.873853687139385
GO:0140299	molecular sensor activity	6/1659	71/18639	0.0845070422535211	0.949443496421567	0.613912027967929	0.873853687139385
GO:0030165	PDZ domain binding	7/1659	83/18639	0.0843373493975904	0.947536983376544	0.615825404313059	0.873853687139385
GO:0008276	protein methyltransferase activity	8/1659	95/18639	0.0842105263157895	0.946112115732369	0.618031755906325	0.873853687139385
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	2/1659	23/18639	0.0869565217391304	0.97696359776712	0.61966567655138	0.873853687139385
GO:0099186	structural constituent of postsynapse	2/1659	23/18639	0.0869565217391304	0.97696359776712	0.61966567655138	0.873853687139385
GO:0140102	catalytic activity, acting on a rRNA	2/1659	23/18639	0.0869565217391304	0.97696359776712	0.61966567655138	0.873853687139385
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	2/1659	23/18639	0.0869565217391304	0.97696359776712	0.61966567655138	0.873853687139385
GO:0019888	protein phosphatase regulator activity	9/1659	107/18639	0.0841121495327103	0.94500684456913	0.620407050723896	0.873853687139385
GO:0035403	histone H3T6 kinase activity	21/1659	247/18639	0.0850202429149798	0.955209347614411	0.620502229462866	0.873853687139385
GO:0031072	heat shock protein binding	11/1659	131/18639	0.083969465648855	0.943403779523211	0.625399597480588	0.873853687139385
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	5/1659	60/18639	0.0833333333333333	0.93625678119349	0.627623479023552	0.873853687139385
GO:0004679	AMP-activated protein kinase activity	21/1659	248/18639	0.0846774193548387	0.951357697019191	0.628001520917538	0.873853687139385
GO:0004527	exonuclease activity	7/1659	84/18639	0.0833333333333333	0.93625678119349	0.628600818443964	0.873853687139385
GO:0038187	pattern recognition receptor activity	4/1659	48/18639	0.0833333333333333	0.93625678119349	0.628929749758145	0.873853687139385
GO:0004843	cysteine-type deubiquitinase activity	9/1659	108/18639	0.0833333333333333	0.93625678119349	0.631655481396643	0.873853687139385
GO:0000993	RNA polymerase II complex binding	3/1659	36/18639	0.0833333333333333	0.93625678119349	0.632933320147322	0.873853687139385
GO:0005179	hormone activity	11/1659	132/18639	0.0833333333333333	0.93625678119349	0.635547612042738	0.873853687139385
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0000099	sulfur amino acid transmembrane transporter activity	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0003953	NAD+ nucleosidase activity	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0005536	D-glucose binding	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0008432	JUN kinase binding	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0010854	adenylate cyclase regulator activity	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0015173	aromatic amino acid transmembrane transporter activity	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0032404	mismatch repair complex binding	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0032794	GTPase activating protein binding	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0034056	estrogen response element binding	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0047676	arachidonate-CoA ligase activity	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0050786	RAGE receptor binding	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0070990	snRNP binding	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0140537	transcription regulator activator activity	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0180030	inositol phosphate kinase activity	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:1900750	oligopeptide binding	1/1659	11/18639	0.0909090909090909	1.02137103402926	0.641457538520105	0.873853687139385
GO:0004620	phospholipase activity	9/1659	109/18639	0.0825688073394495	0.927667269439421	0.642722101592076	0.873853687139385
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	2/1659	24/18639	0.0833333333333333	0.93625678119349	0.64311703941157	0.873853687139385
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	2/1659	24/18639	0.0833333333333333	0.93625678119349	0.64311703941157	0.873853687139385
GO:0004622	lysophospholipase activity	2/1659	24/18639	0.0833333333333333	0.93625678119349	0.64311703941157	0.873853687139385
GO:0004806	triacylglycerol lipase activity	2/1659	24/18639	0.0833333333333333	0.93625678119349	0.64311703941157	0.873853687139385
GO:0005540	hyaluronic acid binding	2/1659	24/18639	0.0833333333333333	0.93625678119349	0.64311703941157	0.873853687139385
GO:0015149	hexose transmembrane transporter activity	2/1659	24/18639	0.0833333333333333	0.93625678119349	0.64311703941157	0.873853687139385
GO:0019957	C-C chemokine binding	2/1659	24/18639	0.0833333333333333	0.93625678119349	0.64311703941157	0.873853687139385
GO:0030552	cAMP binding	2/1659	24/18639	0.0833333333333333	0.93625678119349	0.64311703941157	0.873853687139385
GO:0042625	ATPase-coupled ion transmembrane transporter activity	2/1659	24/18639	0.0833333333333333	0.93625678119349	0.64311703941157	0.873853687139385
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	2/1659	24/18639	0.0833333333333333	0.93625678119349	0.64311703941157	0.873853687139385
GO:0046961	proton-transporting ATPase activity, rotational mechanism	2/1659	24/18639	0.0833333333333333	0.93625678119349	0.64311703941157	0.873853687139385
GO:0055056	D-glucose transmembrane transporter activity	2/1659	24/18639	0.0833333333333333	0.93625678119349	0.64311703941157	0.873853687139385
GO:0051082	unfolded protein binding	10/1659	121/18639	0.0826446280991736	0.928519121844783	0.644032588700836	0.873974640688378
GO:0016763	pentosyltransferase activity	4/1659	49/18639	0.0816326530612245	0.917149499944643	0.645310328598161	0.873974640688378
GO:0060590	ATPase regulator activity	4/1659	49/18639	0.0816326530612245	0.917149499944643	0.645310328598161	0.873974640688378
GO:0008194	UDP-glycosyltransferase activity	12/1659	145/18639	0.0827586206896552	0.929799837874914	0.6472122370725	0.875598748525879
GO:0008168	methyltransferase activity	17/1659	204/18639	0.0833333333333333	0.93625678119349	0.648588165448945	0.875827633824964
GO:0019213	deacetylase activity	3/1659	37/18639	0.0810810810810811	0.910952543863936	0.651618999176353	0.875827633824964
GO:0015291	secondary active transmembrane transporter activity	24/1659	287/18639	0.0836236933797909	0.939518999943293	0.656925972403467	0.875827633824964
GO:0004709	MAP kinase kinase kinase activity	2/1659	25/18639	0.08	0.898806509945751	0.665409760506513	0.875827633824964
GO:0005251	delayed rectifier potassium channel activity	2/1659	25/18639	0.08	0.898806509945751	0.665409760506513	0.875827633824964
GO:0005537	D-mannose binding	2/1659	25/18639	0.08	0.898806509945751	0.665409760506513	0.875827633824964
GO:0015645	fatty acid ligase activity	2/1659	25/18639	0.08	0.898806509945751	0.665409760506513	0.875827633824964
GO:0015662	P-type ion transporter activity	2/1659	25/18639	0.08	0.898806509945751	0.665409760506513	0.875827633824964
GO:0120515	fatty acid-CoA ligase activity	2/1659	25/18639	0.08	0.898806509945751	0.665409760506513	0.875827633824964
GO:0140358	P-type transmembrane transporter activity	2/1659	25/18639	0.08	0.898806509945751	0.665409760506513	0.875827633824964
GO:0005501	retinoid binding	3/1659	38/18639	0.0789473684210526	0.886980108499096	0.669613927713316	0.875827633824964
GO:0019840	isoprenoid binding	3/1659	38/18639	0.0789473684210526	0.886980108499096	0.669613927713316	0.875827633824964
GO:0042162	telomeric DNA binding	3/1659	38/18639	0.0789473684210526	0.886980108499096	0.669613927713316	0.875827633824964
GO:0003720	telomerase activity	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0004032	aldose reductase (NADPH) activity	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0004126	cytidine deaminase activity	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0004300	enoyl-CoA hydratase activity	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0004859	phospholipase inhibitor activity	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0005527	macrolide binding	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0008179	adenylate cyclase binding	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0008603	cAMP-dependent protein kinase regulator activity	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0015132	prostaglandin transmembrane transporter activity	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0015166	polyol transmembrane transporter activity	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0015368	calcium:monoatomic cation antiporter activity	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0016840	carbon-nitrogen lyase activity	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0031543	peptidyl-proline dioxygenase activity	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0034452	dynactin binding	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0035197	siRNA binding	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0035497	cAMP response element binding	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0042301	phosphate ion binding	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0043047	single-stranded telomeric DNA binding	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0070679	inositol 1,4,5 trisphosphate binding	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0097677	STAT family protein binding	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/1659	12/18639	0.0833333333333333	0.93625678119349	0.673389143823688	0.875827633824964
GO:0001217	DNA-binding transcription repressor activity	23/1659	278/18639	0.0827338129496403	0.929521120897134	0.67505694324827	0.87708128392841
GO:0030544	Hsp70 protein binding	4/1659	51/18639	0.0784313725490196	0.881182852887991	0.67661034469993	0.878183843225117
GO:0017022	myosin binding	6/1659	76/18639	0.0789473684210526	0.886980108499096	0.67994394049848	0.880431330341353
GO:0004112	cyclic-nucleotide phosphodiesterase activity	2/1659	26/18639	0.0769230769230769	0.864237028793991	0.686564182335453	0.880431330341353
GO:0005112	Notch binding	2/1659	26/18639	0.0769230769230769	0.864237028793991	0.686564182335453	0.880431330341353
GO:0008143	poly(A) binding	2/1659	26/18639	0.0769230769230769	0.864237028793991	0.686564182335453	0.880431330341353
GO:0015145	monosaccharide transmembrane transporter activity	2/1659	26/18639	0.0769230769230769	0.864237028793991	0.686564182335453	0.880431330341353
GO:0070006	metalloaminopeptidase activity	2/1659	26/18639	0.0769230769230769	0.864237028793991	0.686564182335453	0.880431330341353
GO:0019842	vitamin binding	12/1659	150/18639	0.08	0.898806509945751	0.692941846981688	0.880431330341353
GO:0002161	aminoacyl-tRNA editing activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0003964	RNA-directed DNA polymerase activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0004465	lipoprotein lipase activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0004535	poly(A)-specific ribonuclease activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0004993	G protein-coupled serotonin receptor activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0005035	death receptor activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0005172	vascular endothelial growth factor receptor binding	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0005542	folic acid binding	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0030955	potassium ion binding	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0031432	titin binding	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0035673	oligopeptide transmembrane transporter activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0046974	histone H3K9 methyltransferase activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0046975	histone H3K36 methyltransferase activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0070700	BMP receptor binding	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0071714	icosanoid transmembrane transporter activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0071837	HMG box domain binding	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0089720	caspase binding	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0140333	glycerophospholipid flippase activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0140666	annealing activity	1/1659	13/18639	0.0769230769230769	0.864237028793991	0.702478498545141	0.880431330341353
GO:0004177	aminopeptidase activity	3/1659	40/18639	0.075	0.842631103074141	0.703532607109737	0.880431330341353
GO:0004532	RNA exonuclease activity	3/1659	40/18639	0.075	0.842631103074141	0.703532607109737	0.880431330341353
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3/1659	40/18639	0.075	0.842631103074141	0.703532607109737	0.880431330341353
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	3/1659	40/18639	0.075	0.842631103074141	0.703532607109737	0.880431330341353
GO:0101005	deubiquitinase activity	9/1659	115/18639	0.0782608695652174	0.879267237990408	0.705052924686267	0.880431330341353
GO:0005544	calcium-dependent phospholipid binding	4/1659	53/18639	0.0754716981132075	0.847930669760142	0.705934425641119	0.880431330341353
GO:0001671	ATPase activator activity	2/1659	27/18639	0.0740740740740741	0.832228249949769	0.706606204126286	0.880431330341353
GO:0004364	glutathione transferase activity	2/1659	27/18639	0.0740740740740741	0.832228249949769	0.706606204126286	0.880431330341353
GO:0008395	steroid hydroxylase activity	2/1659	27/18639	0.0740740740740741	0.832228249949769	0.706606204126286	0.880431330341353
GO:0016405	CoA-ligase activity	2/1659	27/18639	0.0740740740740741	0.832228249949769	0.706606204126286	0.880431330341353
GO:0061650	ubiquitin-like protein conjugating enzyme activity	3/1659	41/18639	0.0731707317073171	0.822079124950381	0.719464944519647	0.890497209534217
GO:0140828	metal cation:monoatomic cation antiporter activity	3/1659	41/18639	0.0731707317073171	0.822079124950381	0.719464944519647	0.890497209534217
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	4/1659	54/18639	0.0740740740740741	0.832228249949769	0.719852781246141	0.890497209534217
GO:0005242	inward rectifier potassium channel activity	2/1659	28/18639	0.0714285714285714	0.802505812451563	0.725566132678412	0.890497209534217
GO:0050698	proteoglycan sulfotransferase activity	2/1659	28/18639	0.0714285714285714	0.802505812451563	0.725566132678412	0.890497209534217
GO:0051119	sugar transmembrane transporter activity	2/1659	28/18639	0.0714285714285714	0.802505812451563	0.725566132678412	0.890497209534217
GO:0005506	iron ion binding	12/1659	154/18639	0.0779220779220779	0.875460886310796	0.726837611563124	0.890497209534217
GO:0004705	JUN kinase activity	1/1659	14/18639	0.0714285714285714	0.802505812451563	0.728978454032826	0.890497209534217
GO:0008195	phosphatidate phosphatase activity	1/1659	14/18639	0.0714285714285714	0.802505812451563	0.728978454032826	0.890497209534217
GO:0008494	translation activator activity	1/1659	14/18639	0.0714285714285714	0.802505812451563	0.728978454032826	0.890497209534217
GO:0015386	potassium:proton antiporter activity	1/1659	14/18639	0.0714285714285714	0.802505812451563	0.728978454032826	0.890497209534217
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/1659	14/18639	0.0714285714285714	0.802505812451563	0.728978454032826	0.890497209534217
GO:0032454	histone H3K9 demethylase activity	1/1659	14/18639	0.0714285714285714	0.802505812451563	0.728978454032826	0.890497209534217
GO:0043176	amine binding	1/1659	14/18639	0.0714285714285714	0.802505812451563	0.728978454032826	0.890497209534217
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/1659	14/18639	0.0714285714285714	0.802505812451563	0.728978454032826	0.890497209534217
GO:0061783	peptidoglycan muralytic activity	1/1659	14/18639	0.0714285714285714	0.802505812451563	0.728978454032826	0.890497209534217
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/1659	14/18639	0.0714285714285714	0.802505812451563	0.728978454032826	0.890497209534217
GO:0098847	sequence-specific single stranded DNA binding	1/1659	14/18639	0.0714285714285714	0.802505812451563	0.728978454032826	0.890497209534217
GO:1901474	azole transmembrane transporter activity	1/1659	14/18639	0.0714285714285714	0.802505812451563	0.728978454032826	0.890497209534217
GO:1901612	cardiolipin binding	1/1659	14/18639	0.0714285714285714	0.802505812451563	0.728978454032826	0.890497209534217
GO:0016298	lipase activity	10/1659	130/18639	0.0769230769230769	0.864237028793991	0.730604018737371	0.891073595010209
GO:0016741	transferase activity, transferring one-carbon groups	17/1659	215/18639	0.0790697674418605	0.888355271458009	0.730880589165677	0.891073595010209
GO:0004520	DNA endonuclease activity	3/1659	42/18639	0.0714285714285714	0.802505812451563	0.734722929354447	0.893136360951845
GO:0019894	kinesin binding	3/1659	42/18639	0.0714285714285714	0.802505812451563	0.734722929354447	0.893136360951845
GO:0043175	RNA polymerase core enzyme binding	3/1659	42/18639	0.0714285714285714	0.802505812451563	0.734722929354447	0.893136360951845
GO:0001618	virus receptor activity	6/1659	81/18639	0.0740740740740741	0.832228249949769	0.738183604223651	0.896468587585448
GO:0035250	UDP-galactosyltransferase activity	2/1659	29/18639	0.0689655172413793	0.774833198229095	0.743477693549098	0.897119261364953
GO:0099604	ligand-gated calcium channel activity	2/1659	29/18639	0.0689655172413793	0.774833198229095	0.743477693549098	0.897119261364953
GO:0106222	lncRNA binding	2/1659	29/18639	0.0689655172413793	0.774833198229095	0.743477693549098	0.897119261364953
GO:0030170	pyridoxal phosphate binding	4/1659	56/18639	0.0714285714285714	0.802505812451563	0.746212251636763	0.897119261364953
GO:0170055	lipid transmembrane transporter activity	4/1659	56/18639	0.0714285714285714	0.802505812451563	0.746212251636763	0.897119261364953
GO:0140272	exogenous protein binding	6/1659	82/18639	0.0731707317073171	0.822079124950381	0.748870579680273	0.897119261364953
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3/1659	43/18639	0.0697674418604651	0.783842886580596	0.749317207847788	0.897119261364953
GO:0004867	serine-type endopeptidase inhibitor activity	7/1659	95/18639	0.0736842105263158	0.827848101265823	0.752088831637704	0.897119261364953
GO:0004467	long-chain fatty acid-CoA ligase activity	1/1659	15/18639	0.0666666666666667	0.749005424954792	0.753119379925956	0.897119261364953
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/1659	15/18639	0.0666666666666667	0.749005424954792	0.753119379925956	0.897119261364953
GO:0005523	tropomyosin binding	1/1659	15/18639	0.0666666666666667	0.749005424954792	0.753119379925956	0.897119261364953
GO:0010181	FMN binding	1/1659	15/18639	0.0666666666666667	0.749005424954792	0.753119379925956	0.897119261364953
GO:0030553	cGMP binding	1/1659	15/18639	0.0666666666666667	0.749005424954792	0.753119379925956	0.897119261364953
GO:0031005	filamin binding	1/1659	15/18639	0.0666666666666667	0.749005424954792	0.753119379925956	0.897119261364953
GO:0034483	heparan sulfate sulfotransferase activity	1/1659	15/18639	0.0666666666666667	0.749005424954792	0.753119379925956	0.897119261364953
GO:0047372	monoacylglycerol lipase activity	1/1659	15/18639	0.0666666666666667	0.749005424954792	0.753119379925956	0.897119261364953
GO:0050700	CARD domain binding	1/1659	15/18639	0.0666666666666667	0.749005424954792	0.753119379925956	0.897119261364953
GO:0050780	dopamine receptor binding	1/1659	15/18639	0.0666666666666667	0.749005424954792	0.753119379925956	0.897119261364953
GO:0051371	muscle alpha-actinin binding	1/1659	15/18639	0.0666666666666667	0.749005424954792	0.753119379925956	0.897119261364953
GO:0140776	protein-containing complex destabilizing activity	1/1659	15/18639	0.0666666666666667	0.749005424954792	0.753119379925956	0.897119261364953
GO:0070279	vitamin B6 binding	4/1659	57/18639	0.0701754385964912	0.788426763110307	0.758661964628173	0.899743561472091
GO:0015108	chloride transmembrane transporter activity	9/1659	121/18639	0.0743801652892562	0.835667209660305	0.759966707577095	0.899743561472091
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/1659	30/18639	0.0666666666666667	0.749005424954792	0.760377183170234	0.899743561472091
GO:0008187	poly-pyrimidine tract binding	2/1659	30/18639	0.0666666666666667	0.749005424954792	0.760377183170234	0.899743561472091
GO:0016769	transferase activity, transferring nitrogenous groups	2/1659	30/18639	0.0666666666666667	0.749005424954792	0.760377183170234	0.899743561472091
GO:0031624	ubiquitin conjugating enzyme binding	2/1659	30/18639	0.0666666666666667	0.749005424954792	0.760377183170234	0.899743561472091
GO:0098918	structural constituent of synapse	2/1659	30/18639	0.0666666666666667	0.749005424954792	0.760377183170234	0.899743561472091
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	21/1659	268/18639	0.0783582089552239	0.880360853958058	0.761440748458513	0.900147222561013
GO:0043014	alpha-tubulin binding	3/1659	44/18639	0.0681818181818182	0.766028275521946	0.763260364178443	0.901443046224019
GO:0004708	MAP kinase kinase activity	1/1659	16/18639	0.0625	0.702192585895118	0.775111161965412	0.905686535442279
GO:0008296	3'-5'-DNA exonuclease activity	1/1659	16/18639	0.0625	0.702192585895118	0.775111161965412	0.905686535442279
GO:0015378	sodium:chloride symporter activity	1/1659	16/18639	0.0625	0.702192585895118	0.775111161965412	0.905686535442279
GO:0015385	sodium:proton antiporter activity	1/1659	16/18639	0.0625	0.702192585895118	0.775111161965412	0.905686535442279
GO:0015562	efflux transmembrane transporter activity	1/1659	16/18639	0.0625	0.702192585895118	0.775111161965412	0.905686535442279
GO:0016722	oxidoreductase activity, acting on metal ions	1/1659	16/18639	0.0625	0.702192585895118	0.775111161965412	0.905686535442279
GO:0019841	retinol binding	1/1659	16/18639	0.0625	0.702192585895118	0.775111161965412	0.905686535442279
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/1659	16/18639	0.0625	0.702192585895118	0.775111161965412	0.905686535442279
GO:0140327	flippase activity	1/1659	16/18639	0.0625	0.702192585895118	0.775111161965412	0.905686535442279
GO:0140328	floppase activity	1/1659	16/18639	0.0625	0.702192585895118	0.775111161965412	0.905686535442279
GO:0005452	solute:inorganic anion antiporter activity	2/1659	31/18639	0.0645161290322581	0.72484395963367	0.776302744664811	0.905686535442279
GO:0016878	acid-thiol ligase activity	2/1659	31/18639	0.0645161290322581	0.72484395963367	0.776302744664811	0.905686535442279
GO:0070273	phosphatidylinositol-4-phosphate binding	2/1659	31/18639	0.0645161290322581	0.72484395963367	0.776302744664811	0.905686535442279
GO:0140789	histone phosphatase activity	10/1659	136/18639	0.0735294117647059	0.826108924582491	0.779909428739186	0.908399899602323
GO:0008170	N-methyltransferase activity	7/1659	98/18639	0.0714285714285714	0.802505812451563	0.780086591151272	0.908399899602323
GO:0070888	E-box binding	4/1659	59/18639	0.0677966101694915	0.761700432157416	0.782132385614497	0.908945594377981
GO:0008509	monoatomic anion transmembrane transporter activity	11/1659	149/18639	0.0738255033557047	0.829435537701615	0.783434038432338	0.908945594377981
GO:0008083	growth factor activity	12/1659	162/18639	0.0740740740740741	0.832228249949769	0.787071900726667	0.908945594377981
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3/1659	46/18639	0.0652173913043478	0.73272269832534	0.789251595633148	0.908945594377981
GO:0008378	galactosyltransferase activity	2/1659	32/18639	0.0625	0.702192585895118	0.791293752080495	0.908945594377981
GO:0031369	translation initiation factor binding	2/1659	32/18639	0.0625	0.702192585895118	0.791293752080495	0.908945594377981
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/1659	32/18639	0.0625	0.702192585895118	0.791293752080495	0.908945594377981
GO:0043425	bHLH transcription factor binding	2/1659	32/18639	0.0625	0.702192585895118	0.791293752080495	0.908945594377981
GO:0070717	poly-purine tract binding	2/1659	32/18639	0.0625	0.702192585895118	0.791293752080495	0.908945594377981
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/1659	17/18639	0.0588235294117647	0.660887139665993	0.79514502236918	0.908945594377981
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/1659	17/18639	0.0588235294117647	0.660887139665993	0.79514502236918	0.908945594377981
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/1659	17/18639	0.0588235294117647	0.660887139665993	0.79514502236918	0.908945594377981
GO:0016018	cyclosporin A binding	1/1659	17/18639	0.0588235294117647	0.660887139665993	0.79514502236918	0.908945594377981
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/1659	17/18639	0.0588235294117647	0.660887139665993	0.79514502236918	0.908945594377981
GO:0031489	myosin V binding	1/1659	17/18639	0.0588235294117647	0.660887139665993	0.79514502236918	0.908945594377981
GO:0032977	membrane insertase activity	1/1659	17/18639	0.0588235294117647	0.660887139665993	0.79514502236918	0.908945594377981
GO:0036041	long-chain fatty acid binding	1/1659	17/18639	0.0588235294117647	0.660887139665993	0.79514502236918	0.908945594377981
GO:0045125	bioactive lipid receptor activity	1/1659	17/18639	0.0588235294117647	0.660887139665993	0.79514502236918	0.908945594377981
GO:0070402	NADPH binding	1/1659	17/18639	0.0588235294117647	0.660887139665993	0.79514502236918	0.908945594377981
GO:0070492	oligosaccharide binding	1/1659	17/18639	0.0588235294117647	0.660887139665993	0.79514502236918	0.908945594377981
GO:0016879	ligase activity, forming carbon-nitrogen bonds	3/1659	48/18639	0.0625	0.702192585895118	0.812825487206652	0.923593916487726
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	1/1659	18/18639	0.0555555555555556	0.624171187462327	0.81339517852263	0.923593916487726
GO:0004706	JUN kinase kinase kinase activity	1/1659	18/18639	0.0555555555555556	0.624171187462327	0.81339517852263	0.923593916487726
GO:0015373	monoatomic anion:sodium symporter activity	1/1659	18/18639	0.0555555555555556	0.624171187462327	0.81339517852263	0.923593916487726
GO:0016854	racemase and epimerase activity	1/1659	18/18639	0.0555555555555556	0.624171187462327	0.81339517852263	0.923593916487726
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/1659	18/18639	0.0555555555555556	0.624171187462327	0.81339517852263	0.923593916487726
GO:0031690	adrenergic receptor binding	1/1659	18/18639	0.0555555555555556	0.624171187462327	0.81339517852263	0.923593916487726
GO:0015179	L-amino acid transmembrane transporter activity	4/1659	62/18639	0.0645161290322581	0.72484395963367	0.813889342137659	0.923593916487726
GO:0003727	single-stranded RNA binding	6/1659	89/18639	0.0674157303370786	0.757421216246419	0.814858542901351	0.92385236074166
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	2/1659	34/18639	0.0588235294117647	0.660887139665993	0.818632713004148	0.927287600366517
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	9/1659	130/18639	0.0692307692307692	0.777813325914592	0.828136131586948	0.927869499161859
GO:0003756	protein disulfide isomerase activity	1/1659	19/18639	0.0526315789473684	0.591320072332731	0.830020354336547	0.927869499161859
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/1659	19/18639	0.0526315789473684	0.591320072332731	0.830020354336547	0.927869499161859
GO:0008301	DNA binding, bending	1/1659	19/18639	0.0526315789473684	0.591320072332731	0.830020354336547	0.927869499161859
GO:0008381	mechanosensitive monoatomic ion channel activity	1/1659	19/18639	0.0526315789473684	0.591320072332731	0.830020354336547	0.927869499161859
GO:0008574	plus-end-directed microtubule motor activity	1/1659	19/18639	0.0526315789473684	0.591320072332731	0.830020354336547	0.927869499161859
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/1659	19/18639	0.0526315789473684	0.591320072332731	0.830020354336547	0.927869499161859
GO:0016918	retinal binding	1/1659	19/18639	0.0526315789473684	0.591320072332731	0.830020354336547	0.927869499161859
GO:0022821	solute:potassium antiporter activity	1/1659	19/18639	0.0526315789473684	0.591320072332731	0.830020354336547	0.927869499161859
GO:0042577	lipid phosphatase activity	1/1659	19/18639	0.0526315789473684	0.591320072332731	0.830020354336547	0.927869499161859
GO:0046527	glucosyltransferase activity	1/1659	19/18639	0.0526315789473684	0.591320072332731	0.830020354336547	0.927869499161859
GO:0099589	serotonin receptor activity	1/1659	19/18639	0.0526315789473684	0.591320072332731	0.830020354336547	0.927869499161859
GO:0000175	3'-5'-RNA exonuclease activity	2/1659	35/18639	0.0571428571428571	0.64200464996125	0.831061284963591	0.927869499161859
GO:0005343	organic acid:sodium symporter activity	2/1659	35/18639	0.0571428571428571	0.64200464996125	0.831061284963591	0.927869499161859
GO:0016229	steroid dehydrogenase activity	2/1659	35/18639	0.0571428571428571	0.64200464996125	0.831061284963591	0.927869499161859
GO:0034061	DNA polymerase activity	2/1659	35/18639	0.0571428571428571	0.64200464996125	0.831061284963591	0.927869499161859
GO:0004175	endopeptidase activity	31/1659	405/18639	0.0765432098765432	0.859969191614761	0.836094921771364	0.93265378023914
GO:0160215	deacylase activity	4/1659	65/18639	0.0615384615384615	0.691389623035193	0.841746778464782	0.933577824522272
GO:0008237	metallopeptidase activity	13/1659	184/18639	0.0706521739130435	0.793782923185785	0.844063439283466	0.933577824522272
GO:0001614	purinergic nucleotide receptor activity	1/1659	20/18639	0.05	0.561754068716094	0.845165157352426	0.933577824522272
GO:0001972	retinoic acid binding	1/1659	20/18639	0.05	0.561754068716094	0.845165157352426	0.933577824522272
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/1659	20/18639	0.05	0.561754068716094	0.845165157352426	0.933577824522272
GO:0005326	neurotransmitter transmembrane transporter activity	1/1659	20/18639	0.05	0.561754068716094	0.845165157352426	0.933577824522272
GO:0010851	cyclase regulator activity	1/1659	20/18639	0.05	0.561754068716094	0.845165157352426	0.933577824522272
GO:0015095	magnesium ion transmembrane transporter activity	1/1659	20/18639	0.05	0.561754068716094	0.845165157352426	0.933577824522272
GO:0016502	nucleotide receptor activity	1/1659	20/18639	0.05	0.561754068716094	0.845165157352426	0.933577824522272
GO:0030742	GTP-dependent protein binding	1/1659	20/18639	0.05	0.561754068716094	0.845165157352426	0.933577824522272
GO:0043024	ribosomal small subunit binding	1/1659	20/18639	0.05	0.561754068716094	0.845165157352426	0.933577824522272
GO:0022829	wide pore channel activity	2/1659	37/18639	0.0540540540540541	0.607301695909291	0.853635692383705	0.94043330920433
GO:0030551	cyclic nucleotide binding	2/1659	37/18639	0.0540540540540541	0.607301695909291	0.853635692383705	0.94043330920433
GO:0042805	actinin binding	2/1659	37/18639	0.0540540540540541	0.607301695909291	0.853635692383705	0.94043330920433
GO:0008373	sialyltransferase activity	1/1659	21/18639	0.0476190476190476	0.535003874967709	0.858961333513999	0.942135406301446
GO:0010314	phosphatidylinositol-5-phosphate binding	1/1659	21/18639	0.0476190476190476	0.535003874967709	0.858961333513999	0.942135406301446
GO:0015125	bile acid transmembrane transporter activity	1/1659	21/18639	0.0476190476190476	0.535003874967709	0.858961333513999	0.942135406301446
GO:0036122	BMP binding	1/1659	21/18639	0.0476190476190476	0.535003874967709	0.858961333513999	0.942135406301446
GO:0061891	calcium ion sensor activity	1/1659	21/18639	0.0476190476190476	0.535003874967709	0.858961333513999	0.942135406301446
GO:0016251	RNA polymerase II general transcription initiation factor activity	3/1659	53/18639	0.0566037735849057	0.635948002320107	0.862146114816802	0.944796885718325
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	2/1659	38/18639	0.0526315789473684	0.591320072332731	0.863859123754283	0.945303275968903
GO:0046943	carboxylic acid transmembrane transporter activity	13/1659	188/18639	0.0691489361702128	0.77689392482013	0.864125546812665	0.945303275968903
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	5/1659	82/18639	0.0609756097560976	0.685065937458651	0.865184560079906	0.945631545490844
GO:0005342	organic acid transmembrane transporter activity	13/1659	189/18639	0.0687830687830688	0.772783374953357	0.868810291464013	0.947578553613583
GO:0005243	gap junction channel activity	1/1659	22/18639	0.0454545454545455	0.510685517014631	0.871528910466426	0.947578553613583
GO:0008649	rRNA methyltransferase activity	1/1659	22/18639	0.0454545454545455	0.510685517014631	0.871528910466426	0.947578553613583
GO:0008970	phospholipase A1 activity	1/1659	22/18639	0.0454545454545455	0.510685517014631	0.871528910466426	0.947578553613583
GO:0031683	G-protein beta/gamma-subunit complex binding	1/1659	22/18639	0.0454545454545455	0.510685517014631	0.871528910466426	0.947578553613583
GO:0140784	metal ion sensor activity	1/1659	22/18639	0.0454545454545455	0.510685517014631	0.871528910466426	0.947578553613583
GO:0001216	DNA-binding transcription activator activity	37/1659	491/18639	0.0753564154786151	0.846635459979449	0.8780290067786	0.951721141992915
GO:0046982	protein heterodimerization activity	27/1659	369/18639	0.0731707317073171	0.822079124950381	0.881460468943604	0.951721141992915
GO:0015144	carbohydrate transmembrane transporter activity	2/1659	40/18639	0.05	0.561754068716094	0.882365162020371	0.951721141992915
GO:0003887	DNA-directed DNA polymerase activity	1/1659	23/18639	0.0434782608695652	0.48848179888356	0.882977239280746	0.951721141992915
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/1659	23/18639	0.0434782608695652	0.48848179888356	0.882977239280746	0.951721141992915
GO:0005212	structural constituent of eye lens	1/1659	23/18639	0.0434782608695652	0.48848179888356	0.882977239280746	0.951721141992915
GO:0005283	amino acid:sodium symporter activity	1/1659	23/18639	0.0434782608695652	0.48848179888356	0.882977239280746	0.951721141992915
GO:0016493	C-C chemokine receptor activity	1/1659	23/18639	0.0434782608695652	0.48848179888356	0.882977239280746	0.951721141992915
GO:0017134	fibroblast growth factor binding	1/1659	23/18639	0.0434782608695652	0.48848179888356	0.882977239280746	0.951721141992915
GO:0043274	phospholipase binding	1/1659	23/18639	0.0434782608695652	0.48848179888356	0.882977239280746	0.951721141992915
GO:0008236	serine-type peptidase activity	13/1659	194/18639	0.0670103092783505	0.752866277660745	0.890343324486977	0.958407511297766
GO:0015175	neutral L-amino acid transmembrane transporter activity	2/1659	41/18639	0.0487804878048781	0.548052749966921	0.8907190193281	0.958407511297766
GO:0005315	phosphate transmembrane transporter activity	1/1659	24/18639	0.0416666666666667	0.468128390596745	0.893405943622884	0.959641211856994
GO:0015295	solute:proton symporter activity	1/1659	24/18639	0.0416666666666667	0.468128390596745	0.893405943622884	0.959641211856994
GO:0008408	3'-5' exonuclease activity	3/1659	58/18639	0.0517241379310345	0.581124898671821	0.899661882235301	0.965528600572942
GO:0015294	solute:monoatomic cation symporter activity	7/1659	116/18639	0.0603448275862069	0.677979048450458	0.900610661596009	0.965715046771624
GO:0047617	fatty acyl-CoA hydrolase activity	1/1659	25/18639	0.04	0.449403254972875	0.902905784586066	0.967343600682922
GO:0017171	serine hydrolase activity	13/1659	198/18639	0.0656565656565657	0.737656857910023	0.905424333651325	0.969208522104425
GO:0015293	symporter activity	9/1659	146/18639	0.0616438356164384	0.692573509376006	0.91125163135292	0.970204925198439
GO:0001637	G protein-coupled chemoattractant receptor activity	1/1659	26/18639	0.0384615384615385	0.432118514396995	0.911559448676091	0.970204925198439
GO:0004950	chemokine receptor activity	1/1659	26/18639	0.0384615384615385	0.432118514396995	0.911559448676091	0.970204925198439
GO:0005227	calcium-activated cation channel activity	1/1659	26/18639	0.0384615384615385	0.432118514396995	0.911559448676091	0.970204925198439
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	1/1659	26/18639	0.0384615384615385	0.432118514396995	0.911559448676091	0.970204925198439
GO:0016289	acyl-CoA hydrolase activity	1/1659	26/18639	0.0384615384615385	0.432118514396995	0.911559448676091	0.970204925198439
GO:0016790	thiolester hydrolase activity	2/1659	44/18639	0.0454545454545455	0.510685517014631	0.912584407971565	0.970204925198439
GO:0030020	extracellular matrix structural constituent conferring tensile strength	2/1659	44/18639	0.0454545454545455	0.510685517014631	0.912584407971565	0.970204925198439
GO:0016836	hydro-lyase activity	3/1659	61/18639	0.0491803278688525	0.552544985622388	0.917488006361179	0.974586577942054
GO:0008266	poly(U) RNA binding	1/1659	27/18639	0.037037037037037	0.416114124974884	0.91944226577416	0.97583054783186
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	35/1659	484/18639	0.0723140495867769	0.812454231614186	0.920721963364089	0.976357077746089
GO:0008514	organic anion transmembrane transporter activity	18/1659	269/18639	0.0669144981412639	0.75178983173901	0.922464695418493	0.977373308241022
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/1659	46/18639	0.0434782608695652	0.48848179888356	0.924804417375702	0.977622428168583
GO:0008528	G protein-coupled peptide receptor activity	7/1659	122/18639	0.0573770491803279	0.644635816559452	0.925646650434283	0.977622428168583
GO:0051393	alpha-actinin binding	1/1659	28/18639	0.0357142857142857	0.401252906225781	0.926622863296225	0.977622428168583
GO:0051537	2 iron, 2 sulfur cluster binding	1/1659	28/18639	0.0357142857142857	0.401252906225781	0.926622863296225	0.977622428168583
GO:0051959	dynein light intermediate chain binding	1/1659	28/18639	0.0357142857142857	0.401252906225781	0.926622863296225	0.977622428168583
GO:0015370	solute:sodium symporter activity	4/1659	79/18639	0.0506329113924051	0.5688648797125	0.929543007982573	0.979090173830222
GO:0015103	inorganic anion transmembrane transporter activity	10/1659	165/18639	0.0606060606060606	0.680914022686175	0.929585614479255	0.979090173830222
GO:0005416	amino acid:monoatomic cation symporter activity	1/1659	29/18639	0.0344827586206897	0.387416599114548	0.933163762215765	0.980021702229399
GO:0033192	calmodulin-dependent protein phosphatase activity	4/1659	81/18639	0.0493827160493827	0.554818833299846	0.937620460554999	0.980021702229399
GO:0140791	histone H2AXS140 phosphatase activity	4/1659	81/18639	0.0493827160493827	0.554818833299846	0.937620460554999	0.980021702229399
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	4/1659	81/18639	0.0493827160493827	0.554818833299846	0.937620460554999	0.980021702229399
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	4/1659	81/18639	0.0493827160493827	0.554818833299846	0.937620460554999	0.980021702229399
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	4/1659	81/18639	0.0493827160493827	0.554818833299846	0.937620460554999	0.980021702229399
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	4/1659	81/18639	0.0493827160493827	0.554818833299846	0.937620460554999	0.980021702229399
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	4/1659	81/18639	0.0493827160493827	0.554818833299846	0.937620460554999	0.980021702229399
GO:1990439	MAP kinase serine/threonine phosphatase activity	4/1659	81/18639	0.0493827160493827	0.554818833299846	0.937620460554999	0.980021702229399
GO:0022839	monoatomic ion-gated channel activity	1/1659	30/18639	0.0333333333333333	0.374502712477396	0.939121920113887	0.980021702229399
GO:0051721	protein phosphatase 2A binding	1/1659	30/18639	0.0333333333333333	0.374502712477396	0.939121920113887	0.980021702229399
GO:0033549	MAP kinase phosphatase activity	4/1659	82/18639	0.0487804878048781	0.548052749966921	0.941335122117825	0.980172507749742
GO:0005249	voltage-gated potassium channel activity	5/1659	98/18639	0.0510204081632653	0.573218437465402	0.943666281025987	0.980172507749742
GO:0042626	ATPase-coupled transmembrane transporter activity	5/1659	98/18639	0.0510204081632653	0.573218437465402	0.943666281025987	0.980172507749742
GO:0017147	Wnt-protein binding	1/1659	31/18639	0.032258064516129	0.362421979816835	0.944549225962189	0.980172507749742
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	4/1659	83/18639	0.0481927710843374	0.541449704786597	0.944846975230171	0.980172507749742
GO:0001653	peptide receptor activity	7/1659	128/18639	0.0546875	0.614418512658228	0.944995917607693	0.980172507749742
GO:0017018	myosin phosphatase activity	4/1659	84/18639	0.0476190476190476	0.535003874967709	0.948165556716279	0.980172507749742
GO:0030145	manganese ion binding	3/1659	68/18639	0.0441176470588235	0.495665354749495	0.948389984885769	0.980172507749742
GO:0005272	sodium channel activity	2/1659	51/18639	0.0392156862745098	0.440591426443995	0.948674071606501	0.980172507749742
GO:0016829	lyase activity	12/1659	200/18639	0.06	0.674104882459313	0.948988725920929	0.980172507749742
GO:0015106	bicarbonate transmembrane transporter activity	1/1659	32/18639	0.03125	0.351096292947559	0.949492950926115	0.980172507749742
GO:0030515	snoRNA binding	1/1659	32/18639	0.03125	0.351096292947559	0.949492950926115	0.980172507749742
GO:0042910	xenobiotic transmembrane transporter activity	1/1659	32/18639	0.03125	0.351096292947559	0.949492950926115	0.980172507749742
GO:0015079	potassium ion transmembrane transporter activity	9/1659	160/18639	0.05625	0.631973327305606	0.953206879113906	0.982543382554729
GO:0019239	deaminase activity	1/1659	33/18639	0.0303030303030303	0.340457011343087	0.953996159095813	0.982543382554729
GO:0015171	amino acid transmembrane transporter activity	5/1659	102/18639	0.0490196078431373	0.550739283054994	0.955322155966022	0.982543382554729
GO:0005246	calcium channel regulator activity	2/1659	53/18639	0.0377358490566038	0.423965334880071	0.956031730129533	0.982543382554729
GO:0008146	sulfotransferase activity	2/1659	53/18639	0.0377358490566038	0.423965334880071	0.956031730129533	0.982543382554729
GO:0004252	serine-type endopeptidase activity	10/1659	176/18639	0.0568181818181818	0.638356896268289	0.957023331189263	0.982543382554729
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/1659	34/18639	0.0294117647058824	0.330443569832996	0.958098081704651	0.982543382554729
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/1659	34/18639	0.0294117647058824	0.330443569832996	0.958098081704651	0.982543382554729
GO:0004190	aspartic-type endopeptidase activity	1/1659	36/18639	0.0277777777777778	0.312085593731163	0.965237846277964	0.989051279985479
GO:0030280	structural constituent of skin epidermis	1/1659	37/18639	0.027027027027027	0.303650847954645	0.96833790610836	0.990598547628092
GO:0070001	aspartic-type peptidase activity	1/1659	37/18639	0.027027027027027	0.303650847954645	0.96833790610836	0.990598547628092
GO:0005267	potassium channel activity	6/1659	124/18639	0.0483870967741935	0.543632969725252	0.969517844628832	0.990991988849487
GO:0004222	metalloendopeptidase activity	5/1659	110/18639	0.0454545454545455	0.510685517014631	0.972290533824371	0.993011479627185
GO:0140662	ATP-dependent protein folding chaperone	1/1659	40/18639	0.025	0.280877034358047	0.97607649619797	0.99606168244281
GO:0008227	G protein-coupled amine receptor activity	1/1659	41/18639	0.024390243902439	0.27402637498346	0.978210433119717	0.997422421986225
GO:0008375	acetylglucosaminyltransferase activity	1/1659	43/18639	0.0232558139534884	0.261280962193532	0.981924539942393	0.999683637801819
GO:0005254	chloride channel activity	3/1659	83/18639	0.036144578313253	0.406087278589947	0.982032722848657	0.999683637801819
GO:0005253	monoatomic anion channel activity	4/1659	103/18639	0.0388349514563107	0.43631383977949	0.984907620561985	0.999999999770676
GO:0003777	microtubule motor activity	2/1659	68/18639	0.0294117647058824	0.330443569832996	0.986614665264761	0.999999999770676
GO:0004497	monooxygenase activity	4/1659	106/18639	0.0377358490566038	0.423965334880071	0.98768212230189	0.999999999770676
GO:0003730	mRNA 3'-UTR binding	14/1659	262/18639	0.0534351145038168	0.600347859696589	0.988671854219684	0.999999999770676
GO:0016597	amino acid binding	1/1659	51/18639	0.0196078431372549	0.220295713221998	0.991442224488109	0.999999999770676
GO:0016830	carbon-carbon lyase activity	1/1659	51/18639	0.0196078431372549	0.220295713221998	0.991442224488109	0.999999999770676
GO:0015085	calcium ion transmembrane transporter activity	6/1659	147/18639	0.0408163265306122	0.458574749972322	0.992281686021098	0.999999999770676
GO:0015081	sodium ion transmembrane transporter activity	7/1659	164/18639	0.0426829268292683	0.479546156221056	0.992586076169238	0.999999999770676
GO:0099094	ligand-gated monoatomic cation channel activity	5/1659	136/18639	0.0367647058823529	0.413054462291246	0.994733978934198	0.999999999770676
GO:0022843	voltage-gated monoatomic cation channel activity	5/1659	143/18639	0.034965034965035	0.392835013088178	0.996710144267708	0.999999999770676
GO:0005262	calcium channel activity	4/1659	131/18639	0.0305343511450382	0.343055919826622	0.997884078142889	0.999999999770676
GO:0005261	monoatomic cation channel activity	15/1659	341/18639	0.0439882697947214	0.49421179065932	0.999556415015145	0.999999999770676
GO:0005244	voltage-gated monoatomic ion channel activity	5/1659	173/18639	0.0289017341040462	0.324713334517973	0.999598310589699	0.999999999770676
GO:0046873	metal ion transmembrane transporter activity	22/1659	450/18639	0.0488888888888889	0.549270644966848	0.999601237423945	0.999999999770676
GO:0022832	voltage-gated channel activity	5/1659	175/18639	0.0285714285714286	0.321002324980625	0.999652363419412	0.999999999770676
GO:0015276	ligand-gated monoatomic ion channel activity	5/1659	186/18639	0.0268817204301075	0.302018316514029	0.999844292978403	0.999999999770676
GO:0022834	ligand-gated channel activity	5/1659	188/18639	0.0265957446808511	0.29880535570005	0.999865642599734	0.999999999770676
GO:0030594	neurotransmitter receptor activity	1/1659	97/18639	0.0103092783505155	0.115825581178576	0.999884568445319	0.999999999770676
GO:0005216	monoatomic ion channel activity	18/1659	448/18639	0.0401785714285714	0.451409519504004	0.999983658666119	0.999999999770676
GO:0022836	gated channel activity	8/1659	318/18639	0.0251572327044025	0.282643556586714	0.999999237110855	0.999999999770676
GO:0045182	translation regulator activity	9/1659	356/18639	0.0252808988764045	0.284032956092407	0.999999797112787	0.999999999770676
GO:0030371	translation repressor activity	4/1659	329/18639	0.0121580547112462	0.136596734034309	0.999999999770676	0.999999999770676