category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Genetic Information Processing	Translation	hsa03010	Ribosome	48/166	222/9376	12.2123086942364	RPL13A/RPS26/RPL10/RPS11/RPS8/RPL28/RPL8/RPL18A/RPL13/RPS20/RPS15/RPL37A/RPS2/UBA52/RPL7/RPS28/RPLP2/RPS5/RPS14/RPLP0/RPL23/RPL35/RPS27/RPL27A/RPL36/RPS9/RPL21/RPL11/RPL18/RPL31/RPL5/RPL29/RPS27A/RPS16/RPS6/RPL12/RPL19/RPLP1/RACK1/RPS19/RPL34/MRPS10/RPS18/RPL6/RPSA/MRPS12/RPL15/RPS4X	22.6973913802003
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	49/166	238/9376	11.6286321757619	RPL13A/RPS26/RPL10/RPS11/RPS8/RPL28/C1QB/RPL8/C1QA/RPL18A/RPL13/RPS20/RPS15/RPL37A/RPS2/UBA52/RPL7/RPS28/RPLP2/RPS5/RPS14/RPLP0/RPL23/RPL35/RPS27/CFD/RPL27A/RPL36/RPS9/RPL21/RPL11/RPL18/RPL31/RPL5/RPL29/RPS27A/RPS16/RPS6/RPL12/RPL19/RPLP1/RPS19/RPL34/C1QC/RPS18/RPL6/RPSA/RPL15/RPS4X	22.2971906113495
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	15/166	275/9376	3.08083242059146	MT-CYB/MT-ND3/C1QB/C1QA/MT-CO2/MT-CO3/MT-ND2/MT-CO1/MT-ATP6/C1QC/PSMC1/PSMD4/CREB3/PSMD14/MT-ND4	4.70184992048321
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	13/166	235/9376	3.12453217123814	MT-CYB/MT-ND3/MT-CO2/MT-CO3/ACTB/MT-ND2/RPS6/MT-CO1/MT-ATP6/NPR1/KDM3B/CREB3/MT-ND4	4.42802695242797
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	13/166	268/9376	2.73979500089912	MT-CYB/MT-ND3/MT-CO2/MT-CO3/UBA52/MT-ND2/RPS27A/MT-CO1/MT-ATP6/PSMC1/PSMD4/PSMD14/MT-ND4	3.8793934820117
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	8/166	138/9376	3.27431464990396	MT-CYB/MT-ND3/MT-CO2/MT-CO3/MT-ND2/MT-CO1/MT-ATP6/MT-ND4	3.61335790025536
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	10/166	205/9376	2.7552159858948	MT-CYB/MT-ND3/MT-CO2/MT-CO3/MT-ND2/MT-CO1/CTSD/MT-ATP6/GAPDH/MT-ND4	3.41121440192816
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	6/166	88/9376	3.85104052573932	C1QB/SERPINE2/C1QA/CFD/C1QC/CLU	3.60739326740302
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	6/166	99/9376	3.42314713399051	HLA-DRB5/C1QB/C1QA/KRT19/CFD/C1QC	3.25389452752816
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	10/166	233/9376	2.42411706913491	DCN/FN1/MYL9/ACTB/FBLN1/INF2/VCAN/TPM1/COL6A3/ITGB8	2.95521552457063
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	12/166	308/9376	2.20059458613675	MT-CYB/MT-ND3/MT-CO2/MT-CO3/MT-ND2/MT-CO1/MT-ATP6/PSMC1/PSMD4/CREB3/PSMD14/MT-ND4	2.87624482507269
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	14/166	388/9376	2.03800770090672	MT-CYB/MT-ND3/MT-CO2/MT-CO3/APOE/DKK1/MT-ND2/MT-CO1/MT-ATP6/PSMC1/PSMD4/GAPDH/PSMD14/MT-ND4	2.80346264431728
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	5/166	87/9376	3.24608779947376	MT-CYB/MT-CO2/MT-CO3/MT-CO1/TPM1	2.82560688942994
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	12/166	368/9376	1.84180199057098	MT-CYB/MT-ND3/MT-CO2/MT-CO3/ACTB/MT-ND2/MT-CO1/MT-ATP6/PSMC1/PSMD4/PSMD14/MT-ND4	2.21171689808699
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	3/166	42/9376	4.03442340791738	FTL/FTH1/GPX4	2.64592051724014
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	14/166	480/9376	1.64738955823293	MT-CYB/MT-ND3/MT-CO2/MT-CO3/UBA52/DKK1/MT-ND2/RPS27A/MT-CO1/MT-ATP6/PSMC1/PSMD4/PSMD14/MT-ND4	1.95478406037683
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	3/166	46/9376	3.68360398114196	PSMC1/PSMD4/PSMD14	2.44943764733501
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	8/166	227/9376	1.99055251844382	MT-CYB/MT-ND3/MT-CO2/MT-CO3/MT-ND2/MT-CO1/MT-ATP6/MT-ND4	2.02821265617624
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	7/166	204/9376	1.93810536262698	LUM/DCN/FN1/TIMP3/ACTB/RPS6/CD63	1.81863081863275
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	4/166	89/9376	2.53851360498172	FN1/SPP1/COL6A3/ITGB8	1.95780074173945
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	5/166	134/9376	2.10753461607624	MYL9/CALD1/MYL6/RAMP1/NPR1	1.73355088172763
NA	NA	hsa04382	Cornified envelope formation	7/166	217/9376	1.82199766809172	S100A6/S100A4/KRT19/KRT7/KRT8/S100A11/PPP2R1A	1.64469847614534
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	3/166	63/9376	2.68961560527826	HPGD/GPX4/PTGDS	1.80643879838468
Human Diseases	Immune disease	hsa05310	Asthma	2/166	32/9376	3.53012048192771	HLA-DRB5/PRG2	1.9246849206518
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	4/166	103/9376	2.19347292080945	C1QB/C1QA/PPP2R1A/C1QC	1.63504955267539
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	4/166	105/9376	2.1516924842226	UBA52/GABARAP/RPS27A/RABGEF1	1.59322737106459
Cellular Processes	Cell motility	hsa04814	Motor proteins	6/166	194/9376	1.74686374363433	MYL9/ACTB/MYL6/TPM1/MYO9B/DYNLL2	1.41118341930063
NA	NA	hsa04518	Integrin signaling	5/166	154/9376	1.83382882178063	FN1/ACTB/SPP1/COL6A3/ITGB8	1.40066595048944
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	5/166	154/9376	1.83382882178063	MYL9/ACTB/MYL6/NPR1/EEF2	1.40066595048944
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	6/166	203/9376	1.6694165825865	FN1/MYL9/ACTB/SPP1/COL6A3/ITGB8	1.29448986841668
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/166	78/9376	2.17238183503244	FN1/ACTB/DNM2	1.39582662582988
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/166	78/9376	2.17238183503244	C1QB/C1QA/C1QC	1.39582662582988
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	2/166	44/9376	2.56736035049288	DYNLL2/CREB3	1.39899994213668
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	5/166	170/9376	1.66123316796598	MYL9/ACTB/MYL6/PPP2R1A/DLG1	1.16802858819865
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	9/166	362/9376	1.4042468215403	FN1/SPP1/PRL/PRLR/RPS6/PPP2R1A/CREB3/COL6A3/ITGB8	1.05305726679698
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/166	46/9376	2.45573598742797	FTL/FTH1	1.32871115009643
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	2/166	50/9376	2.25927710843373	AOC1/P4HA2	1.19858399018703
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	3/166	93/9376	1.82199766809172	MYL9/ACTB/KRIT1	1.06949252048632
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	8/166	333/9376	1.35692318824849	FN1/SPP1/PPP2R1A/PSMC1/DLG1/CREB3/COL6A3/ITGB8	0.890328923356623
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	4/166	143/9376	1.57991406184177	HLA-DRB5/C1QB/C1QA/C1QC	0.938145301388017
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	1/166	16/9376	3.53012048192771	MIF	1.35979404975615
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	3/166	99/9376	1.71157356699525	ACTB/TPM1/ITGB8	0.95552816545915
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	3/166	103/9376	1.64510469060709	CSTF2T/NCBP2/PPP2R1A	0.883788913359285
Metabolism	Glycan biosynthesis and metabolism	hsa00511	Other glycan degradation	1/166	18/9376	3.13788487282463	MAN2C1	1.21881815191941
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	3/166	105/9376	1.61376936316695	ACTB/TPM1/ITGB8	0.849075740542443
Organismal Systems	Digestive system	hsa04978	Mineral absorption	2/166	61/9376	1.85186648232273	FTL/FTH1	0.896096716078751
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	1/166	20/9376	2.82409638554217	UGP2	1.09629527211367
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	4/166	157/9376	1.43903000537181	MT-CYB/MT-CO2/MT-CO3/MT-CO1	0.744752532720411
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	3/166	110/9376	1.54041621029573	RPS6/ELOB/GAPDH	0.765399949768051
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	3/166	110/9376	1.54041621029573	DCN/PPP2R1A/EMP3	0.765399949768051
Metabolism	Metabolism of cofactors and vitamins	hsa00770	Pantothenate and CoA biosynthesis	1/166	21/9376	2.68961560527826	COASY	1.04060409494816
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/166	22/9376	2.56736035049288	AOC1	0.988078344298461
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	3/166	116/9376	1.46073950976319	MYL9/ACTB/THY1	0.670330259292842
NA	NA	hsa04081	Hormone signaling	5/166	219/9376	1.28954172855807	PRL/RAMP1/PRLR/THRA/NPR1	0.582058291568432
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	4/166	169/9376	1.33685036001996	UBA52/GABARAP/RPS27A/CTSD	0.593241007385889
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/166	70/9376	1.61376936316695	HLA-DRB5/ACTB	0.691962516577136
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/166	71/9376	1.59104021720686	PRL/PRLR	0.671116453091563
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	3/166	122/9376	1.38889986174205	PPP2R1A/EEF2/CREB3	0.58044733775672
Metabolism	Glycan biosynthesis and metabolism	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	1/166	30/9376	1.88273092369478	PIGT	0.650108653831451
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	6/166	298/9376	1.13722002102369	IL1RL1/PRL/CXCL14/PRLR/EBI3/IL1R2	0.323176960069329
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/166	32/9376	1.76506024096386	UGP2	0.58198805933995
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/166	32/9376	1.76506024096386	GABARAP	0.58198805933995
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/166	137/9376	1.23683053381409	ACTB/CTSD/DFFA	0.374882667078672
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	3/166	138/9376	1.22786799371399	FN1/ACTB/WIPF2	0.362029332808694
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/166	139/9376	1.2190344110254	KRT19/CTSD/CREB3	0.349272300515801
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	5/166	248/9376	1.13874854255733	MYL9/ACTB/DYNLL2/DNM2/GAPDH	0.297287276058361
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	2/166	86/9376	1.31353320257775	ACTB/ITGB8	0.392134248176716
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	5/166	250/9376	1.12963855421687	PSAP/CTSD/CD63/CD68/DNASE2	0.27891625042742
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/166	34/9376	1.66123316796598	RORB	0.518542102383347
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	3/166	142/9376	1.19328016290514	UBA52/RPS27A/ELOB	0.311563366043793
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	5/166	253/9376	1.11624363064908	UBA52/MYL9/ACTB/RPS27A/UBE2V2	0.251634657566654
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/166	89/9376	1.26925680249086	GABARAP/TRAK2	0.342636663028576
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	3/166	144/9376	1.17670682730924	C1QB/C1QA/C1QC	0.286877537709724
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	3/166	144/9376	1.17670682730924	PSMC1/PSMD4/PSMD14	0.286877537709724
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	1/166	36/9376	1.56894243641232	UGP2	0.459151500184953
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/166	36/9376	1.56894243641232	UGP2	0.459151500184953
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/166	37/9376	1.52653858677955	MIF	0.430814929450174
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	1/166	37/9376	1.52653858677955	UGP2	0.430814929450174
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/166	37/9376	1.52653858677955	HBB	0.430814929450174
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/166	38/9376	1.4863665187064	UGP2	0.403309452889161
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	4/166	205/9376	1.10208639435792	HLA-DRB5/PSMC1/PSMD4/PSMD14	0.198402123427062
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	3/166	149/9376	1.13722002102369	MT-ND3/MT-ND2/MT-ND4	0.226668005166438
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/166	39/9376	1.44825455668829	HLA-DRB5	0.376585162068829
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	3/166	154/9376	1.10029729306838	TPM1/PPP2R1A/CREB3	0.168479428460074
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	2/166	98/9376	1.15269240226211	NPR1/CREB3	0.203992005971202
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/166	42/9376	1.34480780263913	AOC1	0.300661416309572
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	3/166	157/9376	1.07927250402885	C1QB/C1QA/C1QC	0.134474631410625
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	3/166	157/9376	1.07927250402885	ACTB/PPP2R1A/DLG1	0.134474631410625
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/166	100/9376	1.12963855421687	HLA-DRB5/IL1R2	0.174970033951512
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	3/166	160/9376	1.05903614457831	HLA-DRB5/VCAN/ITGB8	0.101115239081704
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/166	44/9376	1.28368017524644	MAN1B1	0.253208235509014
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	1/166	44/9376	1.28368017524644	TAF2	0.253208235509014
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/166	44/9376	1.28368017524644	HLA-DRB5	0.253208235509014
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/166	103/9376	1.09673646040473	FN1/IL1R2	0.132528274043178
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	2/166	104/9376	1.08619091751622	LPCAT1/GPAT4	0.118659176274698
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/166	45/9376	1.25515394912985	HLA-DRB5	0.230332023940635
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/166	106/9376	1.0656967492612	CREB3/IL1R2	0.0913201914830122
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	4/166	224/9376	1.00860585197935	HLA-DRB5/DLG1/CREB3/IL1R2	0.0175012771567975
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/166	166/9376	1.02075772971404	MYL9/NPR1/CREB3	0.0362254633195755
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	4/166	226/9376	0.999680136475104	MYL9/FXYD1/NPR1/CREB3	-0.000653458871660032
NA	NA	hsa03272	Virion - Hepatitis viruses	1/166	48/9376	1.17670682730924	CD63	0.16477432699908
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/166	109/9376	1.03636564607052	HLA-DRB5/EBI3	0.0512678189806154
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/166	49/9376	1.15269240226211	CREB3	0.143864733824841
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/166	50/9376	1.12963855421687	HLA-DRB5	0.12339039164191
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/166	50/9376	1.12963855421687	HBB	0.12339039164191
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/166	232/9376	0.973826339842127	FN1/MYL9/ACTB/ITGB8	-0.054193875595028
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/166	51/9376	1.10748877864399	LPCAT1	0.103331721106191
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/166	51/9376	1.10748877864399	ACTB	0.103331721106191
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	3/166	174/9376	0.973826339842127	CRYAB/MAN1B1/BAG1	-0.0467851295050444
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/166	52/9376	1.08619091751622	APOE	0.0836704125573333
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/166	115/9376	0.982294394971189	CREB3/OXSR1	-0.0256472388927242
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/166	53/9376	1.0656967492612	DNM2	0.0643893202896361
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/166	54/9376	1.04596162427488	HLA-DRB5	0.0454723674736695
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/166	55/9376	1.02694414019715	PSAP	0.0269044604779018
Genetic Information Processing	Transcription	hsa03040	Spliceosome	4/166	243/9376	0.929743666022113	NCBP2/SNRNP27/SF3A1/CTNNBL1	-0.148967578876036
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/166	56/9376	1.00860585197935	MAN1B1	0.00867141150654953
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	2/166	122/9376	0.925933241161367	PPP2R1A/DLG1	-0.110547359907958
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/166	122/9376	0.925933241161367	ACTB/THRA	-0.110547359907958
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/166	59/9376	0.957320808658362	HDDC2	-0.0441483022618416
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/166	59/9376	0.957320808658362	GPX4	-0.0441483022618416
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/166	59/9376	0.957320808658362	NPR1	-0.0441483022618416
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/166	125/9376	0.903710843373494	CTSD/PPP2R1A	-0.145494948787263
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/166	60/9376	0.941365461847389	PPP2R1A	-0.061167997238846
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/166	128/9376	0.882530120481928	NPR1/HDDC2	-0.179645964048628
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/166	62/9376	0.910998834045861	CRYAB	-0.0943915877137577
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/166	63/9376	0.896538535092752	PRDM2	-0.110614984711501
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/166	63/9376	0.896538535092752	ERCC6	-0.110614984711501
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/166	133/9376	0.84935229640366	PPP2R1A/CREB3	-0.234904711188309
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/166	65/9376	0.868952734012975	GPAT4	-0.142329966421567
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/166	65/9376	0.868952734012975	CREB3	-0.142329966421567
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/166	65/9376	0.868952734012975	SPP1	-0.142329966421567
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/166	200/9376	0.847228915662651	ACTB/WIPF2/GAPDH	-0.293183364017941
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/166	66/9376	0.855786783497627	HSD11B1	-0.157838177551428
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/166	66/9376	0.855786783497627	HLA-DRB5	-0.157838177551428
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	3/166	201/9376	0.843013846430498	HPGD/NUPR1/IL1R2	-0.302041214577773
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/166	67/9376	0.843013846430498	GAPDH	-0.173123929883527
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	2/166	138/9376	0.818578662475991	PPP2R1A/CPEB4	-0.288236380680639
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/166	205/9376	0.82656479576844	PSMC1/DLG1/CREB3	-0.337066589656454
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/166	69/9376	0.818578662475991	NPR1	-0.203056978691337
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/166	69/9376	0.818578662475991	CREB3	-0.203056978691337
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/166	140/9376	0.806884681583477	SPP1/RPS6	-0.309064161042991
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/166	70/9376	0.806884681583477	HSD11B1	-0.217717875378448
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/166	70/9376	0.806884681583477	ELOB	-0.217717875378448
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/166	142/9376	0.795520108603428	ACTB/IL1R2	-0.329617081723241
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/166	73/9376	0.773725037134841	SERINC5	-0.260553126594543
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/166	75/9376	0.753092369477912	GAPDH	-0.288210758488411
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/166	75/9376	0.753092369477912	CD82	-0.288210758488411
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/166	75/9376	0.753092369477912	CREB3	-0.288210758488411
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/166	76/9376	0.743183259353202	ACTB	-0.301785603981552
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/166	78/9376	0.724127278344146	ZCCHC7	-0.328451430004237
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/166	78/9376	0.724127278344146	HLA-DRB5	-0.328451430004237
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/166	79/9376	0.71496111026384	HSD11B1	-0.341551435529027
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/166	79/9376	0.71496111026384	DNM2	-0.341551435529027
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	2/166	154/9376	0.733531528712252	COASY/UGP2	-0.447613832554611
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/166	80/9376	0.706024096385542	RPS6	-0.354501875407983
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/166	155/9376	0.728799067236689	HLA-DRB5/ACTB	-0.457064913563686
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/166	82/9376	0.6888039964737	HLA-DRB5	-0.379970141208164
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	2/166	158/9376	0.71496111026384	CDKN1C/PPP2R1A	-0.485092071478368
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/166	83/9376	0.680505153142691	DNASE2	-0.392495609042858
NA	NA	hsa04517	IgSF CAM signaling	4/166	299/9376	0.755611073054761	MYL9/ACTB/MYL6/DYNLL2	-0.576575013795824
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/166	85/9376	0.664493267186393	HDDC2	-0.417147206672222
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/166	86/9376	0.656766601288876	CREB3	-0.429280119764502
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	5/166	370/9376	0.763269293389775	NPW/PRL/PRLR/OGFR/THRA	-0.62373390519368
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/166	90/9376	0.627576974564926	CREB3	-0.47659919670192
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/166	168/9376	0.672403901319564	FTL/FTH1	-0.575202246841978
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/166	168/9376	0.672403901319564	PRL/PRLR	-0.575202246841978
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/166	93/9376	0.607332556030574	HLA-DRB5	-0.510895481417502
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/166	93/9376	0.607332556030574	LYZ	-0.510895481417502
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/166	93/9376	0.607332556030574	FN1	-0.510895481417502
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/166	173/9376	0.652970262553103	HLA-DRB5/ACTB	-0.618493157534611
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/166	95/9376	0.594546607482562	HLA-DRB5	-0.533230794157365
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/166	250/9376	0.67778313253012	WIPF2/GBF1/DNM2	-0.693246858869043
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	2/166	178/9376	0.634628401245431	DKK1/NOTUM	-0.660705544290334
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/166	98/9376	0.576346201131055	DNM2	-0.565987481945864
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/166	100/9376	0.564819277108434	CXCL14	-0.587352939249871
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/166	181/9376	0.624109698462358	HLA-DRB5/CTSD	-0.685542538429734
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/166	101/9376	0.559227007038053	CREB3	-0.597900024810122
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/166	101/9376	0.559227007038053	FN1	-0.597900024810122
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/166	103/9376	0.548368230202363	COL6A3	-0.618732365272928
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/166	107/9376	0.52786848327891	CREB3	-0.659399034983776
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/166	108/9376	0.522980812137439	NCBP2	-0.669367436616043
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/166	109/9376	0.51818282303526	SPP1	-0.6792596441839
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/166	109/9376	0.51818282303526	CREB3	-0.6792596441839
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/166	110/9376	0.513472070098576	CPEB4	-0.68907713353662
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/166	196/9376	0.576346201131055	UBA52/RPS27A	-0.804688263722492
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/166	112/9376	0.504302925989673	HLA-DRB5	-0.708493647510847
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/166	115/9376	0.491147197485595	CREB3	-0.737092540248291
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/166	116/9376	0.486913169921064	GAPDH	-0.74649041499248
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/166	117/9376	0.482751518896097	ACTB	-0.755822784970034
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/166	119/9376	0.47463804799028	CREB3	-0.774295674032156
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/166	122/9376	0.462966620580683	CREB3	-0.801542057572637
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	2/166	212/9376	0.532848374630598	ACTB/KRIT1	-0.923619559843671
Organismal Systems	Immune system	hsa04611	Platelet activation	1/166	126/9376	0.448269267546376	ACTB	-0.837050092970996
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/166	130/9376	0.434476367006488	CREB3	-0.871676539308384
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/166	133/9376	0.42467614820183	GABARAP	-0.897101515788908
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/166	133/9376	0.42467614820183	TYROBP	-0.897101515788908
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/166	136/9376	0.415308291991495	RACK1	-0.922083541991518
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/166	138/9376	0.409289331237995	RPS6	-0.938502094169972
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/166	142/9376	0.397760054301714	TYROBP	-0.970797529490274
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/166	149/9376	0.379073340341231	DNM2	-1.02568274111555
NA	NA	hsa04519	Cadherin signaling	4/166	404/9376	0.559227007038053	ACTB/KRT19/KRT7/KRT8	-1.21582450900651
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/166	155/9376	0.364399533618344	CREB3	-1.07120085933226
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/166	156/9376	0.362063639172073	PPP2R1A	-1.07865872907167
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/166	158/9376	0.35748055513192	RPS6	-1.09346864480383
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/166	163/9376	0.346514893931554	CREB3	-1.12989692711819
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/166	170/9376	0.332246633593196	ACTB	-1.1795461262602
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/166	180/9376	0.313788487282463	HLA-DRB5	-1.24797141654267
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/166	184/9376	0.306966998428497	MYL9	-1.27458172300976
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/166	187/9376	0.302042394175633	GABARAP	-1.29427209839987
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/166	191/9376	0.295716899009651	CREB3	-1.32018331057289
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/166	193/9376	0.292652475185717	CXCL14	-1.33299667963589
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/166	195/9376	0.289650911337658	ACTB	-1.34571783038874
NA	NA	hsa04082	Neuroactive ligand signaling	1/166	199/9376	0.28382878246655	OGFR	-1.37089092808634
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/166	214/9376	0.263934241639455	ELOB	-1.46230587550251
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	2/166	323/9376	0.349733298519154	TIMP3/TPM1	-1.59663771427832
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/166	217/9376	0.26028538115596	CREB3	-1.48006199241367
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/166	227/9376	0.248819064805477	CREB3	-1.53808571627618