ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 26/285 175/18639 0.148571428571429 9.71657142857143 1.91121613684998e-18 1.11615022392039e-15 GO:0023026 MHC class II protein complex binding 10/285 27/18639 0.37037037037037 24.2222222222222 4.00292130495154e-12 1.03068972386123e-09 GO:0023023 MHC protein complex binding 11/285 37/18639 0.297297297297297 19.4432432432432 5.29463899243785e-12 1.03068972386123e-09 GO:0042277 peptide binding 22/285 249/18639 0.0883534136546185 5.77831325301205 4.04874844646649e-11 5.91117273184108e-09 GO:0042605 peptide antigen binding 11/285 45/18639 0.244444444444444 15.9866666666667 5.63987947958222e-11 6.58737923215203e-09 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 12/285 68/18639 0.176470588235294 11.5411764705882 4.40504003401413e-10 4.28757229977375e-08 GO:0005201 extracellular matrix structural constituent 17/285 168/18639 0.101190476190476 6.61785714285714 8.80458861670847e-10 7.3455425030825e-08 GO:0009055 electron transfer activity 14/285 116/18639 0.120689655172414 7.89310344827586 2.7870120478043e-09 2.03451879489714e-07 GO:0022853 active monoatomic ion transmembrane transporter activity 14/285 118/18639 0.11864406779661 7.75932203389831 3.49526692561631e-09 2.26803987173325e-07 GO:0015078 proton transmembrane transporter activity 16/285 185/18639 0.0864864864864865 5.65621621621622 2.6729351350991e-08 1.56099411889787e-06 GO:0005178 integrin binding 14/285 161/18639 0.0869565217391304 5.68695652173913 1.87838288433783e-07 9.97250549502995e-06 GO:0045296 cadherin binding 20/285 334/18639 0.0598802395209581 3.91616766467066 2.33198874048236e-07 1.13490118703475e-05 GO:0015399 primary active transmembrane transporter activity 14/285 166/18639 0.0843373493975904 5.51566265060241 2.74132137938445e-07 1.23148591196963e-05 GO:0008201 heparin binding 13/285 172/18639 0.0755813953488372 4.94302325581395 2.53317245310728e-06 0.000101823575370499 GO:0008137 NADH dehydrogenase (ubiquinone) activity 7/285 41/18639 0.170731707317073 11.1658536585366 2.61533155917377e-06 0.000101823575370499 GO:0003823 antigen binding 13/285 174/18639 0.0747126436781609 4.88620689655172 2.88081938432539e-06 0.000105149907527877 GO:0003954 NADH dehydrogenase activity 7/285 44/18639 0.159090909090909 10.4045454545455 4.28653702544746e-06 0.00014725515428596 GO:0001968 fibronectin binding 6/285 30/18639 0.2 13.08 5.28709165851437e-06 0.000171536751587355 GO:0033218 amide binding 15/285 247/18639 0.0607287449392713 3.97165991902834 6.52523308084829e-06 0.000200565058906074 GO:0016651 oxidoreductase activity, acting on NAD(P)H 9/285 88/18639 0.102272727272727 6.68863636363636 8.00445165323067e-06 0.000224883043483752 GO:0050840 extracellular matrix binding 8/285 67/18639 0.119402985074627 7.8089552238806 8.08654779650477e-06 0.000224883043483752 GO:0032395 MHC class II receptor activity 4/285 10/18639 0.4 26.16 1.04539194386243e-05 0.000277504043279846 GO:0005125 cytokine activity 14/285 234/18639 0.0598290598290598 3.91282051282051 1.57011486233709e-05 0.000394929334174104 GO:0042608 T cell receptor binding 4/285 11/18639 0.363636363636364 23.7818181818182 1.62299726372919e-05 0.000394929334174104 GO:0005539 glycosaminoglycan binding 14/285 242/18639 0.0578512396694215 3.78347107438017 2.28501900840753e-05 0.000533780440364 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 7/285 58/18639 0.120689655172414 7.89310344827586 2.80206197181151e-05 0.000629386227514585 GO:0019838 growth factor binding 10/285 136/18639 0.0735294117647059 4.80882352941176 4.66166247993598e-05 0.00100830032899356 GO:0008009 chemokine activity 6/285 45/18639 0.133333333333333 8.72 5.98352519425755e-05 0.00124799239765943 GO:0004129 cytochrome-c oxidase activity 4/285 15/18639 0.266666666666667 17.44 6.39642961419926e-05 0.00128810858437668 GO:0016675 oxidoreductase activity, acting on a heme group of donors 4/285 16/18639 0.25 16.35 8.42622341739175e-05 0.00164030482525226 GO:0005126 cytokine receptor binding 14/285 275/18639 0.0509090909090909 3.32945454545455 9.15714915833676e-05 0.00172508874466731 GO:0097110 scaffold protein binding 7/285 70/18639 0.1 6.54 9.55705703210999e-05 0.00174416290836007 GO:0005518 collagen binding 7/285 72/18639 0.0972222222222222 6.35833333333333 0.000114429560433024 0.00202505646342078 GO:0001540 amyloid-beta binding 7/285 83/18639 0.0843373493975904 5.51566265060241 0.000279624581106703 0.00480296339312689 GO:1901681 sulfur compound binding 13/285 275/18639 0.0472727272727273 3.09163636363636 0.00033412775570023 0.00557516026654098 GO:0019955 cytokine binding 9/285 144/18639 0.0625 4.0875 0.000378795044241812 0.00614489738436717 GO:0042056 chemoattractant activity 5/285 42/18639 0.119047619047619 7.78571428571428 0.000432021668496599 0.00681893660545983 GO:1990948 ubiquitin ligase inhibitor activity 3/285 11/18639 0.272727272727273 17.8363636363636 0.000532943504727494 0.00819050017791728 GO:0140375 immune receptor activity 9/285 156/18639 0.0576923076923077 3.77307692307692 0.000677792140402838 0.0101495028203912 GO:0042379 chemokine receptor binding 6/285 72/18639 0.0833333333333333 5.45 0.000813415860996311 0.0118758715705461 GO:0048020 CCR chemokine receptor binding 5/285 50/18639 0.1 6.54 0.000974199454917299 0.0138764019919927 GO:0008191 metalloendopeptidase inhibitor activity 3/285 14/18639 0.214285714285714 14.0142857142857 0.00113638641786275 0.015433713210043 GO:0044548 S100 protein binding 3/285 14/18639 0.214285714285714 14.0142857142857 0.00113638641786275 0.015433713210043 GO:0002020 protease binding 8/285 136/18639 0.0588235294117647 3.84705882352941 0.00117923825299678 0.0156517077215936 GO:0003779 actin binding 16/285 443/18639 0.036117381489842 2.36207674943567 0.00137224749383071 0.0174515595277251 GO:0140463 chromatin-protein adaptor activity 5/285 54/18639 0.0925925925925926 6.05555555555556 0.00138374508023179 0.0174515595277251 GO:0055105 ubiquitin-protein transferase inhibitor activity 3/285 15/18639 0.2 13.08 0.00140449194829294 0.0174515595277251 GO:0005200 structural constituent of cytoskeleton 7/285 112/18639 0.0625 4.0875 0.00167754742169815 0.0204101602973275 GO:0022804 active transmembrane transporter activity 16/285 457/18639 0.0350109409190372 2.28971553610503 0.00188278774912215 0.0224397560303538 GO:0043394 proteoglycan binding 4/285 37/18639 0.108108108108108 7.07027027027027 0.00237624110126594 0.0277544960627861 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 3/285 18/18639 0.166666666666667 10.9 0.00243483748872099 0.0278812763414325 GO:0061134 peptidase regulator activity 10/285 226/18639 0.0442477876106195 2.89380530973451 0.0025918613575125 0.0291085967843712 GO:0019843 rRNA binding 5/285 65/18639 0.0769230769230769 5.03076923076923 0.00315446648193417 0.0347586495367841 GO:0004866 endopeptidase inhibitor activity 8/285 161/18639 0.0496894409937888 3.24968944099379 0.00339536186725555 0.0367202098236526 GO:0042287 MHC protein binding 4/285 41/18639 0.0975609756097561 6.38048780487805 0.00347380522953563 0.0368854955281602 GO:0008307 structural constituent of muscle 4/285 42/18639 0.0952380952380952 6.22857142857143 0.00379399297280291 0.0395659267163732 GO:0030246 carbohydrate binding 11/285 280/18639 0.0392857142857143 2.56928571428571 0.00402270016848712 0.0412150333052013 GO:0030414 peptidase inhibitor activity 8/285 169/18639 0.0473372781065089 3.09585798816568 0.0045494859546606 0.0458086171986515 GO:0051015 actin filament binding 9/285 209/18639 0.0430622009569378 2.81626794258373 0.00498831831099548 0.0488644220631325 GO:0004857 enzyme inhibitor activity 14/285 416/18639 0.0336538461538462 2.20096153846154 0.00502031733525334 0.0488644220631325 GO:0001664 G protein-coupled receptor binding 11/285 297/18639 0.037037037037037 2.42222222222222 0.00621011797448302 0.0594542442147227 GO:0120020 cholesterol transfer activity 3/285 25/18639 0.12 7.848 0.00634269649250678 0.0597441088971607 GO:0061135 endopeptidase regulator activity 8/285 184/18639 0.0434782608695652 2.84347826086956 0.00750048538997144 0.0694547952124483 GO:0005010 insulin-like growth factor receptor activity 4/285 51/18639 0.0784313725490196 5.12941176470588 0.00761148440684365 0.0694547952124483 GO:0015252 proton channel activity 3/285 27/18639 0.111111111111111 7.26666666666667 0.00788724154117248 0.0708638316929958 GO:0005080 protein kinase C binding 4/285 52/18639 0.0769230769230769 5.03076923076923 0.00814863222806039 0.0721030488058677 GO:0008135 translation factor activity, RNA binding 5/285 83/18639 0.0602409638554217 3.93975903614458 0.00888688492794286 0.0774618029540094 GO:0180051 translation factor activity 5/285 84/18639 0.0595238095238095 3.89285714285714 0.00933431837124865 0.0795265315622718 GO:0004629 phospholipase C activity 3/285 29/18639 0.103448275862069 6.76551724137931 0.00963465930942075 0.0795265315622718 GO:0051861 glycolipid binding 3/285 29/18639 0.103448275862069 6.76551724137931 0.00963465930942075 0.0795265315622718 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/285 10/18639 0.2 13.08 0.00966846530979675 0.0795265315622718 GO:0070325 lipoprotein particle receptor binding 3/285 31/18639 0.0967741935483871 6.32903225806452 0.0115899488725873 0.0898943613108371 GO:0099106 ion channel regulator activity 7/285 160/18639 0.04375 2.86125 0.0116787697120771 0.0898943613108371 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/285 11/18639 0.181818181818182 11.8909090909091 0.0116985812664788 0.0898943613108371 GO:0050998 nitric-oxide synthase binding 2/285 11/18639 0.181818181818182 11.8909090909091 0.0116985812664788 0.0898943613108371 GO:0097493 structural molecule activity conferring elasticity 2/285 11/18639 0.181818181818182 11.8909090909091 0.0116985812664788 0.0898943613108371 GO:0015459 potassium channel regulator activity 4/285 59/18639 0.0677966101694915 4.43389830508475 0.0126107389232636 0.0923217834447558 GO:0071813 lipoprotein particle binding 3/285 32/18639 0.09375 6.13125 0.0126468196499665 0.0923217834447558 GO:0071814 protein-lipid complex binding 3/285 32/18639 0.09375 6.13125 0.0126468196499665 0.0923217834447558 GO:0120015 sterol transfer activity 3/285 32/18639 0.09375 6.13125 0.0126468196499665 0.0923217834447558 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/285 60/18639 0.0666666666666667 4.36 0.0133530324038989 0.0962737151095919 GO:0030296 protein tyrosine kinase activator activity 3/285 33/18639 0.0909090909090909 5.94545454545455 0.0137570631494653 0.0977868086385194 GO:0097371 MDM2/MDM4 family protein binding 2/285 12/18639 0.166666666666667 10.9 0.0138977827345841 0.0977868086385194 GO:0016247 channel regulator activity 7/285 168/18639 0.0416666666666667 2.725 0.0149401614090591 0.103869693605839 GO:0141108 transporter regulator activity 7/285 170/18639 0.0411764705882353 2.69294117647059 0.0158476413369289 0.10838986605155 GO:0004896 cytokine receptor activity 5/285 96/18639 0.0520833333333333 3.40625 0.015961521370605 0.10838986605155 GO:0008035 high-density lipoprotein particle binding 2/285 13/18639 0.153846153846154 10.0615384615385 0.0162604616453104 0.109150685067371 GO:0055106 ubiquitin-protein transferase regulator activity 3/285 36/18639 0.0833333333333333 5.45 0.0174111805950511 0.111737686456152 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/285 36/18639 0.0833333333333333 5.45 0.0174111805950511 0.111737686456152 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/285 36/18639 0.0833333333333333 5.45 0.0174111805950511 0.111737686456152 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/285 36/18639 0.0833333333333333 5.45 0.0174111805950511 0.111737686456152 GO:0044325 transmembrane transporter binding 6/285 136/18639 0.0441176470588235 2.88529411764706 0.0182846807871528 0.116067973692361 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 3/285 39/18639 0.0769230769230769 5.03076923076923 0.0215547387033262 0.135354488201532 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/285 16/18639 0.125 8.175 0.0242752301795972 0.150816323668987 GO:0017080 sodium channel regulator activity 3/285 41/18639 0.0731707317073171 4.78536585365854 0.0245903004397648 0.151165636387607 GO:0016859 cis-trans isomerase activity 3/285 42/18639 0.0714285714285714 4.67142857142857 0.0261900163987619 0.15768009873069 GO:0035198 miRNA binding 3/285 42/18639 0.0714285714285714 4.67142857142857 0.0261900163987619 0.15768009873069 GO:0016018 cyclosporin A binding 2/285 17/18639 0.117647058823529 7.69411764705882 0.0272383168343606 0.159071770312666 GO:0038191 neuropilin binding 2/285 17/18639 0.117647058823529 7.69411764705882 0.0272383168343606 0.159071770312666 GO:0048038 quinone binding 2/285 17/18639 0.117647058823529 7.69411764705882 0.0272383168343606 0.159071770312666 GO:0044183 protein folding chaperone 4/285 75/18639 0.0533333333333333 3.488 0.027907235471302 0.161364609061786 GO:0098631 cell adhesion mediator activity 4/285 76/18639 0.0526315789473684 3.44210526315789 0.0291153111578683 0.165950695845132 GO:0030020 extracellular matrix structural constituent conferring tensile strength 3/285 44/18639 0.0681818181818182 4.45909090909091 0.0295528636436537 0.165950695845132 GO:0030547 signaling receptor inhibitor activity 3/285 44/18639 0.0681818181818182 4.45909090909091 0.0295528636436537 0.165950695845132 GO:0003746 translation elongation factor activity 2/285 18/18639 0.111111111111111 7.26666666666667 0.0303387517525656 0.168741247842841 GO:0019199 transmembrane receptor protein kinase activity 4/285 78/18639 0.0512820512820513 3.35384615384615 0.0316233834622851 0.174226942848816 GO:0034987 immunoglobulin receptor binding 2/285 19/18639 0.105263157894737 6.88421052631579 0.0335716733418552 0.18153571510781 GO:0097001 ceramide binding 2/285 19/18639 0.105263157894737 6.88421052631579 0.0335716733418552 0.18153571510781 GO:0001618 virus receptor activity 4/285 81/18639 0.0493827160493827 3.22962962962963 0.0356165592868973 0.184717865538994 GO:0016004 phospholipase activator activity 2/285 20/18639 0.1 6.54 0.0369323356538056 0.184717865538994 GO:0042288 MHC class I protein binding 2/285 20/18639 0.1 6.54 0.0369323356538056 0.184717865538994 GO:0140272 exogenous protein binding 4/285 82/18639 0.0487804878048781 3.19024390243902 0.0370094859202938 0.184717865538994 GO:0051082 unfolded protein binding 5/285 121/18639 0.0413223140495868 2.70247933884298 0.0383457800432973 0.184717865538994 GO:0005004 GPI-linked ephrin receptor activity 3/285 49/18639 0.0612244897959184 4.00408163265306 0.0389046189405759 0.184717865538994 GO:0005008 hepatocyte growth factor receptor activity 3/285 49/18639 0.0612244897959184 4.00408163265306 0.0389046189405759 0.184717865538994 GO:0005009 insulin receptor activity 3/285 49/18639 0.0612244897959184 4.00408163265306 0.0389046189405759 0.184717865538994 GO:0005011 macrophage colony-stimulating factor receptor activity 3/285 49/18639 0.0612244897959184 4.00408163265306 0.0389046189405759 0.184717865538994 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/285 49/18639 0.0612244897959184 4.00408163265306 0.0389046189405759 0.184717865538994 GO:0005020 stem cell factor receptor activity 3/285 49/18639 0.0612244897959184 4.00408163265306 0.0389046189405759 0.184717865538994 GO:0008288 boss receptor activity 3/285 49/18639 0.0612244897959184 4.00408163265306 0.0389046189405759 0.184717865538994 GO:0036332 placental growth factor receptor activity 3/285 49/18639 0.0612244897959184 4.00408163265306 0.0389046189405759 0.184717865538994 GO:0038062 protein tyrosine kinase collagen receptor activity 3/285 49/18639 0.0612244897959184 4.00408163265306 0.0389046189405759 0.184717865538994 GO:0060175 brain-derived neurotrophic factor receptor activity 3/285 49/18639 0.0612244897959184 4.00408163265306 0.0389046189405759 0.184717865538994 GO:0005006 epidermal growth factor receptor activity 3/285 50/18639 0.06 3.924 0.040934817575894 0.188235696569465 GO:0005007 fibroblast growth factor receptor activity 3/285 50/18639 0.06 3.924 0.040934817575894 0.188235696569465 GO:0005017 platelet-derived growth factor receptor activity 3/285 50/18639 0.06 3.924 0.040934817575894 0.188235696569465 GO:0005019 platelet-derived growth factor beta-receptor activity 3/285 50/18639 0.06 3.924 0.040934817575894 0.188235696569465 GO:0005021 vascular endothelial growth factor receptor activity 3/285 51/18639 0.0588235294117647 3.84705882352941 0.0430175258989596 0.194746008720871 GO:0005030 neurotrophin receptor activity 3/285 51/18639 0.0588235294117647 3.84705882352941 0.0430175258989596 0.194746008720871 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/285 22/18639 0.0909090909090909 5.94545454545455 0.0440184626405333 0.197744478323627 GO:0008081 phosphoric diester hydrolase activity 4/285 87/18639 0.0459770114942529 3.00689655172414 0.0444394446270628 0.198111722612249 GO:0004197 cysteine-type endopeptidase activity 4/285 88/18639 0.0454545454545455 2.97272727272727 0.046018501113657 0.201794995797613 GO:0005003 ephrin receptor activity 3/285 53/18639 0.0566037735849057 3.70188679245283 0.0473388945621112 0.201794995797613 GO:0005005 transmembrane-ephrin receptor activity 3/285 53/18639 0.0566037735849057 3.70188679245283 0.0473388945621112 0.201794995797613 GO:0016860 intramolecular oxidoreductase activity 3/285 53/18639 0.0566037735849057 3.70188679245283 0.0473388945621112 0.201794995797613 GO:0038064 collagen receptor activity 3/285 53/18639 0.0566037735849057 3.70188679245283 0.0473388945621112 0.201794995797613 GO:0051018 protein kinase A binding 3/285 53/18639 0.0566037735849057 3.70188679245283 0.0473388945621112 0.201794995797613 GO:0070577 lysine-acetylated histone binding 2/285 23/18639 0.0869565217391304 5.68695652173913 0.0477349924492424 0.202008953553316 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/285 54/18639 0.0555555555555556 3.63333333333333 0.0495767028824743 0.20746127731964 GO:0072341 modified amino acid binding 4/285 91/18639 0.043956043956044 2.87472527472528 0.0509412923289597 0.20746127731964 GO:0015149 hexose transmembrane transporter activity 2/285 24/18639 0.0833333333333333 5.45 0.0515613887129902 0.20746127731964 GO:0050431 transforming growth factor beta binding 2/285 24/18639 0.0833333333333333 5.45 0.0515613887129902 0.20746127731964 GO:0055056 D-glucose transmembrane transporter activity 2/285 24/18639 0.0833333333333333 5.45 0.0515613887129902 0.20746127731964 GO:0060229 lipase activator activity 2/285 24/18639 0.0833333333333333 5.45 0.0515613887129902 0.20746127731964 GO:0140033 acetylation-dependent protein binding 2/285 24/18639 0.0833333333333333 5.45 0.0515613887129902 0.20746127731964 GO:0098632 cell-cell adhesion mediator activity 3/285 55/18639 0.0545454545454545 3.56727272727273 0.0518653193299099 0.20746127731964 GO:0015662 P-type ion transporter activity 2/285 25/18639 0.08 5.232 0.0554934489060757 0.218974149737488 GO:0140358 P-type transmembrane transporter activity 2/285 25/18639 0.08 5.232 0.0554934489060757 0.218974149737488 GO:0042562 hormone binding 4/285 94/18639 0.0425531914893617 2.78297872340426 0.0561412441449002 0.22002411620114 GO:0004867 serine-type endopeptidase inhibitor activity 4/285 95/18639 0.0421052631578947 2.75368421052632 0.0579357738689721 0.22002411620114 GO:0016853 isomerase activity 6/285 180/18639 0.0333333333333333 2.18 0.0586646822612199 0.22002411620114 GO:0061980 regulatory RNA binding 3/285 58/18639 0.0517241379310345 3.38275862068966 0.0590310731420033 0.22002411620114 GO:0004435 phosphatidylinositol phospholipase C activity 2/285 26/18639 0.0769230769230769 5.03076923076923 0.0595270725338699 0.22002411620114 GO:0008198 ferrous iron binding 2/285 26/18639 0.0769230769230769 5.03076923076923 0.0595270725338699 0.22002411620114 GO:0015145 monosaccharide transmembrane transporter activity 2/285 26/18639 0.0769230769230769 5.03076923076923 0.0595270725338699 0.22002411620114 GO:0030247 polysaccharide binding 2/285 26/18639 0.0769230769230769 5.03076923076923 0.0595270725338699 0.22002411620114 GO:0034237 protein kinase A regulatory subunit binding 2/285 26/18639 0.0769230769230769 5.03076923076923 0.0595270725338699 0.22002411620114 GO:0050750 low-density lipoprotein particle receptor binding 2/285 26/18639 0.0769230769230769 5.03076923076923 0.0595270725338699 0.22002411620114 GO:0001786 phosphatidylserine binding 3/285 59/18639 0.0508474576271186 3.32542372881356 0.0615178767608643 0.225952453008458 GO:0020037 heme binding 5/285 142/18639 0.0352112676056338 2.30281690140845 0.067196881522992 0.240384003372722 GO:0045499 chemorepellent activity 2/285 28/18639 0.0714285714285714 4.67142857142857 0.0678831055938473 0.240384003372722 GO:0046625 sphingolipid binding 2/285 28/18639 0.0714285714285714 4.67142857142857 0.0678831055938473 0.240384003372722 GO:0051119 sugar transmembrane transporter activity 2/285 28/18639 0.0714285714285714 4.67142857142857 0.0678831055938473 0.240384003372722 GO:0097718 disordered domain specific binding 2/285 28/18639 0.0714285714285714 4.67142857142857 0.0678831055938473 0.240384003372722 GO:0031406 carboxylic acid binding 6/285 187/18639 0.0320855614973262 2.09839572192513 0.0679167132816765 0.240384003372722 GO:0019903 protein phosphatase binding 5/285 144/18639 0.0347222222222222 2.27083333333333 0.0704370951340651 0.247264506582583 GO:0043177 organic acid binding 6/285 189/18639 0.0317460317460317 2.07619047619048 0.0707074873275537 0.247264506582583 GO:0008238 exopeptidase activity 4/285 102/18639 0.0392156862745098 2.56470588235294 0.07134263244219 0.248000579441899 GO:0005507 copper ion binding 3/285 63/18639 0.0476190476190476 3.11428571428571 0.0719411080940685 0.248020695918082 GO:0043236 laminin binding 2/285 29/18639 0.0689655172413793 4.51034482758621 0.0721978053186197 0.248020695918082 GO:0048019 receptor antagonist activity 2/285 30/18639 0.0666666666666667 4.36 0.0765986450242718 0.261381729454421 GO:0038024 cargo receptor activity 3/285 65/18639 0.0461538461538462 3.01846153846154 0.0774298616363269 0.261381729454421 GO:0120013 lipid transfer activity 3/285 65/18639 0.0461538461538462 3.01846153846154 0.0774298616363269 0.261381729454421 GO:0005543 phospholipid binding 12/285 497/18639 0.0241448692152917 1.57907444668008 0.0807864707476766 0.271145396072662 GO:0016500 protein-hormone receptor activity 3/285 67/18639 0.0447761194029851 2.92835820895522 0.0830965909453727 0.277305194926272 GO:0046906 tetrapyrrole binding 5/285 152/18639 0.0328947368421053 2.15131578947368 0.0842408916700817 0.279526595087089 GO:0032934 sterol binding 3/285 68/18639 0.0441176470588235 2.88529411764706 0.0859950397226219 0.282782317793177 GO:0004620 phospholipase activity 4/285 109/18639 0.036697247706422 2.4 0.0861905009712081 0.282782317793177 GO:0043022 ribosome binding 4/285 112/18639 0.0357142857142857 2.33571428571429 0.0929787408435195 0.303349634930812 GO:0008376 acetylgalactosaminyltransferase activity 2/285 34/18639 0.0588235294117647 3.84705882352941 0.0949923143709374 0.306494539185787 GO:0015035 protein-disulfide reductase activity 2/285 34/18639 0.0588235294117647 3.84705882352941 0.0949923143709374 0.306494539185787 GO:0001221 transcription coregulator binding 4/285 115/18639 0.0347826086956522 2.27478260869565 0.100013039172439 0.320920960861012 GO:0048029 monosaccharide binding 3/285 74/18639 0.0405405405405405 2.65135135135135 0.104253506264208 0.332042141678397 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/285 36/18639 0.0555555555555556 3.63333333333333 0.104616017241139 0.332042141678397 GO:0015036 disulfide oxidoreductase activity 2/285 40/18639 0.05 3.27 0.124591091512046 0.389097312529597 GO:0015144 carbohydrate transmembrane transporter activity 2/285 40/18639 0.05 3.27 0.124591091512046 0.389097312529597 GO:0071949 FAD binding 2/285 40/18639 0.05 3.27 0.124591091512046 0.389097312529597 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 4/285 128/18639 0.03125 2.04375 0.133163398244239 0.410911791336418 GO:0043021 ribonucleoprotein complex binding 5/285 177/18639 0.0282485875706215 1.84745762711864 0.135620082669995 0.410911791336418 GO:0051117 ATPase binding 3/285 84/18639 0.0357142857142857 2.33571428571429 0.137663475078018 0.410911791336418 GO:0016298 lipase activity 4/285 130/18639 0.0307692307692308 2.01230769230769 0.138622122450511 0.410911791336418 GO:0048156 tau protein binding 2/285 43/18639 0.0465116279069767 3.04186046511628 0.140117830353255 0.410911791336418 GO:0003796 lysozyme activity 1/285 10/18639 0.1 6.54 0.142834064454268 0.410911791336418 GO:0004955 prostaglandin receptor activity 1/285 10/18639 0.1 6.54 0.142834064454268 0.410911791336418 GO:0005528 FK506 binding 1/285 10/18639 0.1 6.54 0.142834064454268 0.410911791336418 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/285 10/18639 0.1 6.54 0.142834064454268 0.410911791336418 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/285 10/18639 0.1 6.54 0.142834064454268 0.410911791336418 GO:0015203 polyamine transmembrane transporter activity 1/285 10/18639 0.1 6.54 0.142834064454268 0.410911791336418 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/285 10/18639 0.1 6.54 0.142834064454268 0.410911791336418 GO:0035374 chondroitin sulfate binding 1/285 10/18639 0.1 6.54 0.142834064454268 0.410911791336418 GO:0043208 glycosphingolipid binding 1/285 10/18639 0.1 6.54 0.142834064454268 0.410911791336418 GO:0050815 phosphoserine residue binding 1/285 10/18639 0.1 6.54 0.142834064454268 0.410911791336418 GO:0099122 RNA polymerase II C-terminal domain binding 1/285 10/18639 0.1 6.54 0.142834064454268 0.410911791336418 GO:0016209 antioxidant activity 3/285 86/18639 0.0348837209302326 2.28139534883721 0.144739073668429 0.412153262138401 GO:0050660 flavin adenine dinucleotide binding 3/285 86/18639 0.0348837209302326 2.28139534883721 0.144739073668429 0.412153262138401 GO:0001223 transcription coactivator binding 2/285 44/18639 0.0454545454545455 2.97272727272727 0.145382828767998 0.412153262138401 GO:0008237 metallopeptidase activity 5/285 184/18639 0.0271739130434783 1.77717391304348 0.152048302880385 0.421863537144791 GO:0002162 dystroglycan binding 1/285 11/18639 0.0909090909090909 5.94545454545455 0.155947612773047 0.421863537144791 GO:0004954 prostanoid receptor activity 1/285 11/18639 0.0909090909090909 5.94545454545455 0.155947612773047 0.421863537144791 GO:0005536 D-glucose binding 1/285 11/18639 0.0909090909090909 5.94545454545455 0.155947612773047 0.421863537144791 GO:0008199 ferric iron binding 1/285 11/18639 0.0909090909090909 5.94545454545455 0.155947612773047 0.421863537144791 GO:0008526 phosphatidylinositol transfer activity 1/285 11/18639 0.0909090909090909 5.94545454545455 0.155947612773047 0.421863537144791 GO:0019107 myristoyltransferase activity 1/285 11/18639 0.0909090909090909 5.94545454545455 0.155947612773047 0.421863537144791 GO:0048185 activin binding 1/285 11/18639 0.0909090909090909 5.94545454545455 0.155947612773047 0.421863537144791 GO:0140031 phosphorylation-dependent protein binding 1/285 11/18639 0.0909090909090909 5.94545454545455 0.155947612773047 0.421863537144791 GO:0004180 carboxypeptidase activity 2/285 46/18639 0.0434782608695652 2.84347826086956 0.156031719217936 0.421863537144791 GO:0008234 cysteine-type peptidase activity 5/285 187/18639 0.0267379679144385 1.74866310160428 0.159333899391022 0.425064484794874 GO:0030295 protein kinase activator activity 4/285 139/18639 0.0287769784172662 1.88201438848921 0.164244589893501 0.425064484794874 GO:0019902 phosphatase binding 5/285 190/18639 0.0263157894736842 1.72105263157895 0.166759215767236 0.425064484794874 GO:0140693 molecular condensate scaffold activity 2/285 48/18639 0.0416666666666667 2.725 0.166823091114549 0.425064484794874 GO:0004713 protein tyrosine kinase activity 4/285 140/18639 0.0285714285714286 1.86857142857143 0.167191729357532 0.425064484794874 GO:0003995 acyl-CoA dehydrogenase activity 1/285 12/18639 0.0833333333333333 5.45 0.168861233685635 0.425064484794874 GO:0005078 MAP-kinase scaffold activity 1/285 12/18639 0.0833333333333333 5.45 0.168861233685635 0.425064484794874 GO:0005095 GTPase inhibitor activity 1/285 12/18639 0.0833333333333333 5.45 0.168861233685635 0.425064484794874 GO:0005527 macrolide binding 1/285 12/18639 0.0833333333333333 5.45 0.168861233685635 0.425064484794874 GO:0015166 polyol transmembrane transporter activity 1/285 12/18639 0.0833333333333333 5.45 0.168861233685635 0.425064484794874 GO:0017166 vinculin binding 1/285 12/18639 0.0833333333333333 5.45 0.168861233685635 0.425064484794874 GO:0031543 peptidyl-proline dioxygenase activity 1/285 12/18639 0.0833333333333333 5.45 0.168861233685635 0.425064484794874 GO:0035259 nuclear glucocorticoid receptor binding 1/285 12/18639 0.0833333333333333 5.45 0.168861233685635 0.425064484794874 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/285 12/18639 0.0833333333333333 5.45 0.168861233685635 0.425064484794874 GO:0070008 serine-type exopeptidase activity 1/285 12/18639 0.0833333333333333 5.45 0.168861233685635 0.425064484794874 GO:1990459 transferrin receptor binding 1/285 12/18639 0.0833333333333333 5.45 0.168861233685635 0.425064484794874 GO:0042393 histone binding 6/285 247/18639 0.0242914979757085 1.58866396761134 0.17841456957943 0.441839714076555 GO:0005172 vascular endothelial growth factor receptor binding 1/285 13/18639 0.0769230769230769 5.03076923076923 0.181577964688995 0.441839714076555 GO:0005542 folic acid binding 1/285 13/18639 0.0769230769230769 5.03076923076923 0.181577964688995 0.441839714076555 GO:0017154 semaphorin receptor activity 1/285 13/18639 0.0769230769230769 5.03076923076923 0.181577964688995 0.441839714076555 GO:0019855 calcium channel inhibitor activity 1/285 13/18639 0.0769230769230769 5.03076923076923 0.181577964688995 0.441839714076555 GO:0031994 insulin-like growth factor I binding 1/285 13/18639 0.0769230769230769 5.03076923076923 0.181577964688995 0.441839714076555 GO:0071837 HMG box domain binding 1/285 13/18639 0.0769230769230769 5.03076923076923 0.181577964688995 0.441839714076555 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/285 13/18639 0.0769230769230769 5.03076923076923 0.181577964688995 0.441839714076555 GO:0019209 kinase activator activity 4/285 148/18639 0.027027027027027 1.76756756756757 0.191416005532697 0.453900587425498 GO:0005161 platelet-derived growth factor receptor binding 1/285 14/18639 0.0714285714285714 4.67142857142857 0.194100797292004 0.453900587425498 GO:0008494 translation activator activity 1/285 14/18639 0.0714285714285714 4.67142857142857 0.194100797292004 0.453900587425498 GO:0016530 metallochaperone activity 1/285 14/18639 0.0714285714285714 4.67142857142857 0.194100797292004 0.453900587425498 GO:0019992 diacylglycerol binding 1/285 14/18639 0.0714285714285714 4.67142857142857 0.194100797292004 0.453900587425498 GO:0031404 chloride ion binding 1/285 14/18639 0.0714285714285714 4.67142857142857 0.194100797292004 0.453900587425498 GO:0032036 myosin heavy chain binding 1/285 14/18639 0.0714285714285714 4.67142857142857 0.194100797292004 0.453900587425498 GO:0034236 protein kinase A catalytic subunit binding 1/285 14/18639 0.0714285714285714 4.67142857142857 0.194100797292004 0.453900587425498 GO:0061783 peptidoglycan muralytic activity 1/285 14/18639 0.0714285714285714 4.67142857142857 0.194100797292004 0.453900587425498 GO:0017046 peptide hormone binding 2/285 53/18639 0.0377358490566038 2.46792452830189 0.19430675831571 0.453900587425498 GO:0015485 cholesterol binding 2/285 54/18639 0.037037037037037 2.42222222222222 0.199873298909296 0.458390432632015 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/285 54/18639 0.037037037037037 2.42222222222222 0.199873298909296 0.458390432632015 GO:0050661 NADP binding 2/285 54/18639 0.037037037037037 2.42222222222222 0.199873298909296 0.458390432632015 GO:0051287 NAD binding 2/285 54/18639 0.037037037037037 2.42222222222222 0.199873298909296 0.458390432632015 GO:0140313 molecular sequestering activity 2/285 55/18639 0.0363636363636364 2.37818181818182 0.205458505685876 0.458390432632015 GO:0000774 adenyl-nucleotide exchange factor activity 1/285 15/18639 0.0666666666666667 4.36 0.206432677709281 0.458390432632015 GO:0004953 icosanoid receptor activity 1/285 15/18639 0.0666666666666667 4.36 0.206432677709281 0.458390432632015 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/285 15/18639 0.0666666666666667 4.36 0.206432677709281 0.458390432632015 GO:0015929 hexosaminidase activity 1/285 15/18639 0.0666666666666667 4.36 0.206432677709281 0.458390432632015 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/285 15/18639 0.0666666666666667 4.36 0.206432677709281 0.458390432632015 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/285 15/18639 0.0666666666666667 4.36 0.206432677709281 0.458390432632015 GO:0033130 acetylcholine receptor binding 1/285 15/18639 0.0666666666666667 4.36 0.206432677709281 0.458390432632015 GO:0045504 dynein heavy chain binding 1/285 15/18639 0.0666666666666667 4.36 0.206432677709281 0.458390432632015 GO:0004601 peroxidase activity 2/285 57/18639 0.0350877192982456 2.29473684210526 0.216677514616062 0.476301046291202 GO:0016504 peptidase activator activity 2/285 57/18639 0.0350877192982456 2.29473684210526 0.216677514616062 0.476301046291202 GO:0008142 oxysterol binding 1/285 16/18639 0.0625 4.0875 0.218576507544593 0.476301046291202 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/285 16/18639 0.0625 4.0875 0.218576507544593 0.476301046291202 GO:0022841 potassium ion leak channel activity 1/285 16/18639 0.0625 4.0875 0.218576507544593 0.476301046291202 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/285 59/18639 0.0338983050847458 2.21694915254237 0.22794949441986 0.479119303797031 GO:0045309 protein phosphorylated amino acid binding 2/285 59/18639 0.0338983050847458 2.21694915254237 0.22794949441986 0.479119303797031 GO:0005496 steroid binding 3/285 108/18639 0.0277777777777778 1.81666666666667 0.229008974783795 0.479119303797031 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/285 17/18639 0.0588235294117647 3.84705882352941 0.230535144463982 0.479119303797031 GO:0008429 phosphatidylethanolamine binding 1/285 17/18639 0.0588235294117647 3.84705882352941 0.230535144463982 0.479119303797031 GO:0019198 transmembrane receptor protein phosphatase activity 1/285 17/18639 0.0588235294117647 3.84705882352941 0.230535144463982 0.479119303797031 GO:0030169 low-density lipoprotein particle binding 1/285 17/18639 0.0588235294117647 3.84705882352941 0.230535144463982 0.479119303797031 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/285 17/18639 0.0588235294117647 3.84705882352941 0.230535144463982 0.479119303797031 GO:0030548 acetylcholine receptor regulator activity 1/285 17/18639 0.0588235294117647 3.84705882352941 0.230535144463982 0.479119303797031 GO:0046965 nuclear retinoid X receptor binding 1/285 17/18639 0.0588235294117647 3.84705882352941 0.230535144463982 0.479119303797031 GO:0051787 misfolded protein binding 1/285 17/18639 0.0588235294117647 3.84705882352941 0.230535144463982 0.479119303797031 GO:0070403 NAD+ binding 1/285 17/18639 0.0588235294117647 3.84705882352941 0.230535144463982 0.479119303797031 GO:1990226 histone methyltransferase binding 1/285 17/18639 0.0588235294117647 3.84705882352941 0.230535144463982 0.479119303797031 GO:0008083 growth factor activity 4/285 162/18639 0.0246913580246914 1.61481481481481 0.236161983254841 0.482968802967654 GO:0004222 metalloendopeptidase activity 3/285 110/18639 0.0272727272727273 1.78363636363636 0.237105927622463 0.482968802967654 GO:0015026 coreceptor activity 2/285 61/18639 0.0327868852459016 2.14426229508197 0.239260954150466 0.482968802967654 GO:0000400 four-way junction DNA binding 1/285 18/18639 0.0555555555555556 3.63333333333333 0.242311402858772 0.482968802967654 GO:0000900 mRNA regulatory element binding translation repressor activity 1/285 18/18639 0.0555555555555556 3.63333333333333 0.242311402858772 0.482968802967654 GO:0008409 5'-3' exonuclease activity 1/285 18/18639 0.0555555555555556 3.63333333333333 0.242311402858772 0.482968802967654 GO:0008525 phosphatidylcholine transporter activity 1/285 18/18639 0.0555555555555556 3.63333333333333 0.242311402858772 0.482968802967654 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/285 18/18639 0.0555555555555556 3.63333333333333 0.242311402858772 0.482968802967654 GO:0035615 clathrin adaptor activity 1/285 18/18639 0.0555555555555556 3.63333333333333 0.242311402858772 0.482968802967654 GO:0098641 cadherin binding involved in cell-cell adhesion 1/285 18/18639 0.0555555555555556 3.63333333333333 0.242311402858772 0.482968802967654 GO:0099602 neurotransmitter receptor regulator activity 1/285 18/18639 0.0555555555555556 3.63333333333333 0.242311402858772 0.482968802967654 GO:1901611 phosphatidylglycerol binding 1/285 18/18639 0.0555555555555556 3.63333333333333 0.242311402858772 0.482968802967654 GO:0003756 protein disulfide isomerase activity 1/285 19/18639 0.0526315789473684 3.44210526315789 0.2539080544986 0.486171487957975 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/285 19/18639 0.0526315789473684 3.44210526315789 0.2539080544986 0.486171487957975 GO:0005520 insulin-like growth factor binding 1/285 19/18639 0.0526315789473684 3.44210526315789 0.2539080544986 0.486171487957975 GO:0008301 DNA binding, bending 1/285 19/18639 0.0526315789473684 3.44210526315789 0.2539080544986 0.486171487957975 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/285 19/18639 0.0526315789473684 3.44210526315789 0.2539080544986 0.486171487957975 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/285 19/18639 0.0526315789473684 3.44210526315789 0.2539080544986 0.486171487957975 GO:0022840 leak channel activity 1/285 19/18639 0.0526315789473684 3.44210526315789 0.2539080544986 0.486171487957975 GO:0022842 narrow pore channel activity 1/285 19/18639 0.0526315789473684 3.44210526315789 0.2539080544986 0.486171487957975 GO:0030506 ankyrin binding 1/285 19/18639 0.0526315789473684 3.44210526315789 0.2539080544986 0.486171487957975 GO:0043395 heparan sulfate proteoglycan binding 1/285 19/18639 0.0526315789473684 3.44210526315789 0.2539080544986 0.486171487957975 GO:0046624 sphingolipid transporter activity 1/285 19/18639 0.0526315789473684 3.44210526315789 0.2539080544986 0.486171487957975 GO:1990380 K48-linked deubiquitinase activity 1/285 19/18639 0.0526315789473684 3.44210526315789 0.2539080544986 0.486171487957975 GO:0035401 histone H3Y41 kinase activity 3/285 115/18639 0.0260869565217391 1.70608695652174 0.257551213499854 0.489934555973663 GO:0140801 histone H2AXY142 kinase activity 3/285 115/18639 0.0260869565217391 1.70608695652174 0.257551213499854 0.489934555973663 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/285 20/18639 0.05 3.27 0.265327829174642 0.4998433943161 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/285 20/18639 0.05 3.27 0.265327829174642 0.4998433943161 GO:0031418 L-ascorbic acid binding 1/285 20/18639 0.05 3.27 0.265327829174642 0.4998433943161 GO:0008235 metalloexopeptidase activity 2/285 66/18639 0.0303030303030303 1.98181818181818 0.267630602596636 0.502560359859922 GO:0140030 modification-dependent protein binding 4/285 173/18639 0.023121387283237 1.5121387283237 0.272889958965802 0.509523263579049 GO:0008373 sialyltransferase activity 1/285 21/18639 0.0476190476190476 3.11428571428571 0.276573415333148 0.509523263579049 GO:0036122 BMP binding 1/285 21/18639 0.0476190476190476 3.11428571428571 0.276573415333148 0.509523263579049 GO:0051010 microtubule plus-end binding 1/285 21/18639 0.0476190476190476 3.11428571428571 0.276573415333148 0.509523263579049 GO:0072542 protein phosphatase activator activity 1/285 21/18639 0.0476190476190476 3.11428571428571 0.276573415333148 0.509523263579049 GO:0140312 cargo adaptor activity 1/285 21/18639 0.0476190476190476 3.11428571428571 0.276573415333148 0.509523263579049 GO:0004175 endopeptidase activity 8/285 405/18639 0.0197530864197531 1.29185185185185 0.28075544961779 0.515601203071665 GO:0008093 cytoskeletal anchor activity 1/285 22/18639 0.0454545454545455 2.97272727272727 0.287647460699463 0.52169601567853 GO:0033691 sialic acid binding 1/285 22/18639 0.0454545454545455 2.97272727272727 0.287647460699463 0.52169601567853 GO:0034062 5'-3' RNA polymerase activity 1/285 22/18639 0.0454545454545455 2.97272727272727 0.287647460699463 0.52169601567853 GO:0097747 RNA polymerase activity 1/285 22/18639 0.0454545454545455 2.97272727272727 0.287647460699463 0.52169601567853 GO:0004602 glutathione peroxidase activity 1/285 23/18639 0.0434782608695652 2.84347826086956 0.298552572892655 0.536476007905571 GO:0005212 structural constituent of eye lens 1/285 23/18639 0.0434782608695652 2.84347826086956 0.298552572892655 0.536476007905571 GO:0017134 fibroblast growth factor binding 1/285 23/18639 0.0434782608695652 2.84347826086956 0.298552572892655 0.536476007905571 GO:0042826 histone deacetylase binding 3/285 127/18639 0.0236220472440945 1.54488188976378 0.307404455465278 0.547351911812261 GO:0015295 solute:proton symporter activity 1/285 24/18639 0.0416666666666667 2.725 0.309291320030901 0.547351911812261 GO:0030215 semaphorin receptor binding 1/285 24/18639 0.0416666666666667 2.725 0.309291320030901 0.547351911812261 GO:0048027 mRNA 5'-UTR binding 1/285 24/18639 0.0416666666666667 2.725 0.309291320030901 0.547351911812261 GO:0070300 phosphatidic acid binding 1/285 24/18639 0.0416666666666667 2.725 0.309291320030901 0.547351911812261 GO:0001848 complement binding 1/285 25/18639 0.04 2.616 0.319866231327769 0.554308246573939 GO:0004709 MAP kinase kinase kinase activity 1/285 25/18639 0.04 2.616 0.319866231327769 0.554308246573939 GO:0005537 D-mannose binding 1/285 25/18639 0.04 2.616 0.319866231327769 0.554308246573939 GO:0015271 outward rectifier potassium channel activity 1/285 25/18639 0.04 2.616 0.319866231327769 0.554308246573939 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/285 25/18639 0.04 2.616 0.319866231327769 0.554308246573939 GO:0019211 phosphatase activator activity 1/285 25/18639 0.04 2.616 0.319866231327769 0.554308246573939 GO:0042974 nuclear retinoic acid receptor binding 1/285 25/18639 0.04 2.616 0.319866231327769 0.554308246573939 GO:0031072 heat shock protein binding 3/285 131/18639 0.0229007633587786 1.49770992366412 0.324139495038226 0.559082324187949 GO:0005179 hormone activity 3/285 132/18639 0.0227272727272727 1.48636363636364 0.328324845211147 0.559082324187949 GO:0004529 DNA exonuclease activity 1/285 26/18639 0.0384615384615385 2.51538461538462 0.330279797679525 0.559082324187949 GO:0005112 Notch binding 1/285 26/18639 0.0384615384615385 2.51538461538462 0.330279797679525 0.559082324187949 GO:0008157 protein phosphatase 1 binding 1/285 26/18639 0.0384615384615385 2.51538461538462 0.330279797679525 0.559082324187949 GO:0052742 phosphatidylinositol kinase activity 1/285 26/18639 0.0384615384615385 2.51538461538462 0.330279797679525 0.559082324187949 GO:0070006 metalloaminopeptidase activity 1/285 26/18639 0.0384615384615385 2.51538461538462 0.330279797679525 0.559082324187949 GO:0120014 phospholipid transfer activity 1/285 26/18639 0.0384615384615385 2.51538461538462 0.330279797679525 0.559082324187949 GO:0046982 protein heterodimerization activity 7/285 369/18639 0.018970189701897 1.24065040650406 0.335388468305024 0.566089206618885 GO:0051087 protein-folding chaperone binding 3/285 134/18639 0.0223880597014925 1.46417910447761 0.336693962139943 0.566654967981922 GO:0005044 scavenger receptor activity 1/285 27/18639 0.037037037037037 2.42222222222222 0.340534472243611 0.567308037693022 GO:0008395 steroid hydroxylase activity 1/285 27/18639 0.037037037037037 2.42222222222222 0.340534472243611 0.567308037693022 GO:0035255 ionotropic glutamate receptor binding 1/285 27/18639 0.037037037037037 2.42222222222222 0.340534472243611 0.567308037693022 GO:0033293 monocarboxylic acid binding 2/285 79/18639 0.0253164556962025 1.65569620253165 0.34096767333947 0.567308037693022 GO:0048306 calcium-dependent protein binding 2/285 80/18639 0.025 1.635 0.346533820512254 0.574931111304421 GO:0005242 inward rectifier potassium channel activity 1/285 28/18639 0.0357142857142857 2.33571428571429 0.350632671008417 0.579279149409785 GO:0019887 protein kinase regulator activity 5/285 255/18639 0.0196078431372549 1.28235294117647 0.351138388512096 0.579279149409785 GO:0070851 growth factor receptor binding 3/285 139/18639 0.0215827338129496 1.41151079136691 0.357585299413261 0.588203451505635 GO:0004181 metallocarboxypeptidase activity 1/285 29/18639 0.0344827586206897 2.2551724137931 0.360576773354482 0.588203451505635 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/285 29/18639 0.0344827586206897 2.2551724137931 0.360576773354482 0.588203451505635 GO:0097472 cyclin-dependent protein kinase activity 1/285 29/18639 0.0344827586206897 2.2551724137931 0.360576773354482 0.588203451505635 GO:0005254 chloride channel activity 2/285 83/18639 0.0240963855421687 1.57590361445783 0.3631360263842 0.589087331689924 GO:0030165 PDZ domain binding 2/285 83/18639 0.0240963855421687 1.57590361445783 0.3631360263842 0.589087331689924 GO:0016769 transferase activity, transferring nitrogenous groups 1/285 30/18639 0.0333333333333333 2.18 0.370369122607247 0.595855558133974 GO:0031210 phosphatidylcholine binding 1/285 30/18639 0.0333333333333333 2.18 0.370369122607247 0.595855558133974 GO:0031624 ubiquitin conjugating enzyme binding 1/285 30/18639 0.0333333333333333 2.18 0.370369122607247 0.595855558133974 GO:0005164 tumor necrosis factor receptor binding 1/285 31/18639 0.032258064516129 2.10967741935484 0.380012026581504 0.608019242530406 GO:0017147 Wnt-protein binding 1/285 31/18639 0.032258064516129 2.10967741935484 0.380012026581504 0.608019242530406 GO:0008194 UDP-glycosyltransferase activity 3/285 145/18639 0.0206896551724138 1.35310344827586 0.382531278454271 0.610377777642881 GO:0016757 glycosyltransferase activity 5/285 267/18639 0.0187265917602996 1.2247191011236 0.387503191700729 0.616626332297617 GO:0005516 calmodulin binding 4/285 207/18639 0.0193236714975845 1.26376811594203 0.390178548139267 0.619196391612315 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/285 33/18639 0.0303030303030303 1.98181818181818 0.398858555609784 0.627852820690333 GO:0019956 chemokine binding 1/285 33/18639 0.0303030303030303 1.98181818181818 0.398858555609784 0.627852820690333 GO:0140311 protein sequestering activity 1/285 33/18639 0.0303030303030303 1.98181818181818 0.398858555609784 0.627852820690333 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/285 91/18639 0.021978021978022 1.43736263736264 0.406570774809841 0.637194941548796 GO:0015020 glucuronosyltransferase activity 1/285 34/18639 0.0294117647058824 1.92352941176471 0.408066623526112 0.637194941548796 GO:0090482 vitamin transmembrane transporter activity 1/285 34/18639 0.0294117647058824 1.92352941176471 0.408066623526112 0.637194941548796 GO:0043178 alcohol binding 2/285 92/18639 0.0217391304347826 1.42173913043478 0.411902453784009 0.639763385664524 GO:0052689 carboxylic ester hydrolase activity 2/285 92/18639 0.0217391304347826 1.42173913043478 0.411902453784009 0.639763385664524 GO:0008017 microtubule binding 5/285 276/18639 0.0181159420289855 1.18478260869565 0.414719238434767 0.642429801713273 GO:0140566 histone reader activity 1/285 35/18639 0.0285714285714286 1.86857142857143 0.417134132921171 0.642878410096031 GO:0051219 phosphoprotein binding 2/285 93/18639 0.021505376344086 1.40645161290323 0.417210475045198 0.642878410096031 GO:0005506 iron ion binding 3/285 154/18639 0.0194805194805195 1.27402597402597 0.419513411824515 0.644725875014518 GO:0000993 RNA polymerase II complex binding 1/285 36/18639 0.0277777777777778 1.81666666666667 0.4260632219406 0.649662980713604 GO:0004190 aspartic-type endopeptidase activity 1/285 36/18639 0.0277777777777778 1.81666666666667 0.4260632219406 0.649662980713604 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/285 36/18639 0.0277777777777778 1.81666666666667 0.4260632219406 0.649662980713604 GO:0030280 structural constituent of skin epidermis 1/285 37/18639 0.027027027027027 1.76756756756757 0.434855996318224 0.6596257190905 GO:0070001 aspartic-type peptidase activity 1/285 37/18639 0.027027027027027 1.76756756756757 0.434855996318224 0.6596257190905 GO:0042626 ATPase-coupled transmembrane transporter activity 2/285 98/18639 0.0204081632653061 1.33469387755102 0.44337812175805 0.664134578055236 GO:0005109 frizzled binding 1/285 38/18639 0.0263157894736842 1.72105263157895 0.443514529865654 0.664134578055236 GO:0005501 retinoid binding 1/285 38/18639 0.0263157894736842 1.72105263157895 0.443514529865654 0.664134578055236 GO:0019840 isoprenoid binding 1/285 38/18639 0.0263157894736842 1.72105263157895 0.443514529865654 0.664134578055236 GO:0042162 telomeric DNA binding 1/285 38/18639 0.0263157894736842 1.72105263157895 0.443514529865654 0.664134578055236 GO:0019207 kinase regulator activity 5/285 287/18639 0.0174216027874564 1.13937282229965 0.447718563203072 0.668715194144742 GO:0000217 DNA secondary structure binding 1/285 39/18639 0.0256410256410256 1.67692307692308 0.452040864954536 0.673448635544513 GO:0004177 aminopeptidase activity 1/285 40/18639 0.025 1.635 0.460437012991523 0.679028322189519 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/285 40/18639 0.025 1.635 0.460437012991523 0.679028322189519 GO:0050997 quaternary ammonium group binding 1/285 40/18639 0.025 1.635 0.460437012991523 0.679028322189519 GO:0071855 neuropeptide receptor binding 1/285 40/18639 0.025 1.635 0.460437012991523 0.679028322189519 GO:0001530 lipopolysaccharide binding 1/285 41/18639 0.024390243902439 1.59512195121951 0.46870495488611 0.684571332459468 GO:0001727 lipid kinase activity 1/285 41/18639 0.024390243902439 1.59512195121951 0.46870495488611 0.684571332459468 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/285 41/18639 0.024390243902439 1.59512195121951 0.46870495488611 0.684571332459468 GO:0005253 monoatomic anion channel activity 2/285 103/18639 0.0194174757281553 1.26990291262136 0.468884474287307 0.684571332459468 GO:0016874 ligase activity 3/285 167/18639 0.0179640718562874 1.1748502994012 0.471540161669053 0.686731806520516 GO:0031492 nucleosomal DNA binding 1/285 42/18639 0.0238095238095238 1.55714285714286 0.476846641511417 0.689303065947196 GO:0043175 RNA polymerase core enzyme binding 1/285 42/18639 0.0238095238095238 1.55714285714286 0.476846641511417 0.689303065947196 GO:0051879 Hsp90 protein binding 1/285 42/18639 0.0238095238095238 1.55714285714286 0.476846641511417 0.689303065947196 GO:0042578 phosphoric ester hydrolase activity 6/285 363/18639 0.0165289256198347 1.08099173553719 0.481336687473218 0.6940756184799 GO:0008200 ion channel inhibitor activity 1/285 43/18639 0.0232558139534884 1.52093023255814 0.484863994158039 0.695726222575663 GO:0008375 acetylglucosaminyltransferase activity 1/285 43/18639 0.0232558139534884 1.52093023255814 0.484863994158039 0.695726222575663 GO:0031625 ubiquitin protein ligase binding 5/285 302/18639 0.0165562913907285 1.08278145695364 0.491906359085471 0.703597067259025 GO:0016248 channel inhibitor activity 1/285 44/18639 0.0227272727272727 1.48636363636364 0.492758904981064 0.703597067259025 GO:0141110 transporter inhibitor activity 1/285 45/18639 0.0222222222222222 1.45333333333333 0.500533237440348 0.712954660158935 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/285 46/18639 0.0217391304347826 1.42173913043478 0.50818882673418 0.717106782029082 GO:0030276 clathrin binding 1/285 46/18639 0.0217391304347826 1.42173913043478 0.50818882673418 0.717106782029082 GO:0030291 protein serine/threonine kinase inhibitor activity 1/285 46/18639 0.0217391304347826 1.42173913043478 0.50818882673418 0.717106782029082 GO:0005319 lipid transporter activity 3/285 178/18639 0.0168539325842697 1.10224719101124 0.513866315655095 0.717106782029082 GO:0001784 phosphotyrosine residue binding 1/285 47/18639 0.0212765957446809 1.39148936170213 0.515727480226395 0.717106782029082 GO:0005504 fatty acid binding 1/285 47/18639 0.0212765957446809 1.39148936170213 0.515727480226395 0.717106782029082 GO:0043495 protein-membrane adaptor activity 1/285 47/18639 0.0212765957446809 1.39148936170213 0.515727480226395 0.717106782029082 GO:0061749 forked DNA-dependent helicase activity 1/285 47/18639 0.0212765957446809 1.39148936170213 0.515727480226395 0.717106782029082 GO:0140359 ABC-type transporter activity 1/285 47/18639 0.0212765957446809 1.39148936170213 0.515727480226395 0.717106782029082 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/285 47/18639 0.0212765957446809 1.39148936170213 0.515727480226395 0.717106782029082 GO:0009378 four-way junction helicase activity 1/285 48/18639 0.0208333333333333 1.3625 0.523150977867072 0.720440154424237 GO:0036121 double-stranded DNA helicase activity 1/285 48/18639 0.0208333333333333 1.3625 0.523150977867072 0.720440154424237 GO:0038187 pattern recognition receptor activity 1/285 48/18639 0.0208333333333333 1.3625 0.523150977867072 0.720440154424237 GO:0043138 3'-5' DNA helicase activity 1/285 48/18639 0.0208333333333333 1.3625 0.523150977867072 0.720440154424237 GO:0005216 monoatomic ion channel activity 7/285 448/18639 0.015625 1.021875 0.530285113196441 0.720440154424237 GO:0140104 molecular carrier activity 4/285 249/18639 0.0160642570281124 1.05060240963855 0.530383832009126 0.720440154424237 GO:0001222 transcription corepressor binding 1/285 49/18639 0.0204081632653061 1.33469387755102 0.530461072606887 0.720440154424237 GO:0016763 pentosyltransferase activity 1/285 49/18639 0.0204081632653061 1.33469387755102 0.530461072606887 0.720440154424237 GO:0035254 glutamate receptor binding 1/285 49/18639 0.0204081632653061 1.33469387755102 0.530461072606887 0.720440154424237 GO:0060590 ATPase regulator activity 1/285 49/18639 0.0204081632653061 1.33469387755102 0.530461072606887 0.720440154424237 GO:0015294 solute:monoatomic cation symporter activity 2/285 116/18639 0.0172413793103448 1.12758620689655 0.531805461308844 0.720590230636577 GO:1990782 protein tyrosine kinase binding 2/285 117/18639 0.0170940170940171 1.11794871794872 0.536431692227518 0.725157373280021 GO:0032813 tumor necrosis factor receptor superfamily binding 1/285 50/18639 0.02 1.308 0.537659490805221 0.725157373280021 GO:0003743 translation initiation factor activity 1/285 51/18639 0.0196078431372549 1.28235294117647 0.544747932632136 0.731339753234867 GO:0005048 signal sequence binding 1/285 51/18639 0.0196078431372549 1.28235294117647 0.544747932632136 0.731339753234867 GO:0044389 ubiquitin-like protein ligase binding 5/285 322/18639 0.015527950310559 1.01552795031056 0.548680419364929 0.734929736030088 GO:0140597 protein carrier chaperone 3/285 188/18639 0.0159574468085106 1.0436170212766 0.550737031282797 0.735996398785248 GO:0015108 chloride transmembrane transporter activity 2/285 121/18639 0.0165289256198347 1.08099173553719 0.554621303742548 0.73949507165673 GO:0005246 calcium channel regulator activity 1/285 53/18639 0.0188679245283019 1.23396226415094 0.558601559274826 0.740381349268671 GO:0008528 G protein-coupled peptide receptor activity 2/285 122/18639 0.0163934426229508 1.07213114754098 0.559089340800486 0.740381349268671 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/285 122/18639 0.0163934426229508 1.07213114754098 0.559089340800486 0.740381349268671 GO:0016758 hexosyltransferase activity 3/285 197/18639 0.0152284263959391 0.995939086294416 0.582476962917771 0.769607570913978 GO:0001653 peptide receptor activity 2/285 128/18639 0.015625 1.021875 0.585224975286865 0.771492969678396 GO:0035591 signaling adaptor activity 2/285 129/18639 0.0155038759689922 1.01395348837209 0.589468365662133 0.775068160697989 GO:0017116 single-stranded DNA helicase activity 1/285 58/18639 0.0172413793103448 1.12758620689655 0.591425181732659 0.775068160697989 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/285 130/18639 0.0153846153846154 1.00615384615385 0.593679523335237 0.775068160697989 GO:0070063 RNA polymerase binding 1/285 59/18639 0.0169491525423729 1.10847457627119 0.597692003927708 0.775068160697989 GO:0070888 E-box binding 1/285 59/18639 0.0169491525423729 1.10847457627119 0.597692003927708 0.775068160697989 GO:0005261 monoatomic cation channel activity 5/285 341/18639 0.0146627565982405 0.958944281524927 0.599670040794509 0.775068160697989 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/285 132/18639 0.0151515151515152 0.990909090909091 0.602005109168655 0.775068160697989 GO:0001098 basal transcription machinery binding 1/285 60/18639 0.0166666666666667 1.09 0.603863036160248 0.775068160697989 GO:0001099 basal RNA polymerase II transcription machinery binding 1/285 60/18639 0.0166666666666667 1.09 0.603863036160248 0.775068160697989 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/285 60/18639 0.0166666666666667 1.09 0.603863036160248 0.775068160697989 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/285 60/18639 0.0166666666666667 1.09 0.603863036160248 0.775068160697989 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/285 60/18639 0.0166666666666667 1.09 0.603863036160248 0.775068160697989 GO:0003714 transcription corepressor activity 3/285 204/18639 0.0147058823529412 0.961764705882353 0.606163384097662 0.776314509458409 GO:0008094 ATP-dependent activity, acting on DNA 3/285 210/18639 0.0142857142857143 0.934285714285714 0.625747128155546 0.799641844295053 GO:0004536 DNA nuclease activity 1/285 64/18639 0.015625 1.021875 0.627618117186515 0.800281616674508 GO:0035091 phosphatidylinositol binding 4/285 284/18639 0.0140845070422535 0.92112676056338 0.634098137877832 0.806782815949137 GO:0045182 translation regulator activity 5/285 356/18639 0.0140449438202247 0.918539325842697 0.637554989940776 0.809417639403072 GO:0003777 microtubule motor activity 1/285 68/18639 0.0147058823529412 0.961764705882353 0.649953379281243 0.821586089827372 GO:0005548 phospholipid transporter activity 1/285 68/18639 0.0147058823529412 0.961764705882353 0.649953379281243 0.821586089827372 GO:0002039 p53 binding 1/285 69/18639 0.0144927536231884 0.947826086956522 0.655325372545194 0.82652157454297 GO:0015293 symporter activity 2/285 146/18639 0.0136986301369863 0.895890410958904 0.656688374294415 0.82652157454297 GO:0015085 calcium ion transmembrane transporter activity 2/285 147/18639 0.0136054421768707 0.889795918367347 0.660355772329238 0.827895455451188 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/285 70/18639 0.0142857142857143 0.934285714285714 0.660615209315503 0.827895455451188 GO:0008509 monoatomic anion transmembrane transporter activity 2/285 149/18639 0.0134228187919463 0.877852348993289 0.667596494816427 0.829407215328068 GO:0019842 vitamin binding 2/285 150/18639 0.0133333333333333 0.872 0.671170021249374 0.829407215328068 GO:0000510 H3-H4 histone complex chaperone activity 2/285 151/18639 0.0132450331125828 0.866225165562914 0.674712466162469 0.829407215328068 GO:0140584 chromatin extrusion motor activity 2/285 151/18639 0.0132450331125828 0.866225165562914 0.674712466162469 0.829407215328068 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/285 151/18639 0.0132450331125828 0.866225165562914 0.674712466162469 0.829407215328068 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/285 151/18639 0.0132450331125828 0.866225165562914 0.674712466162469 0.829407215328068 GO:0004521 RNA endonuclease activity 1/285 73/18639 0.0136986301369863 0.895890410958904 0.6760042068944 0.829407215328068 GO:0043539 protein serine/threonine kinase activator activity 1/285 73/18639 0.0136986301369863 0.895890410958904 0.6760042068944 0.829407215328068 GO:0015616 DNA translocase activity 2/285 152/18639 0.0131578947368421 0.860526315789474 0.678223940868974 0.829407215328068 GO:0140674 ATP-dependent histone chaperone activity 2/285 152/18639 0.0131578947368421 0.860526315789474 0.678223940868974 0.829407215328068 GO:0003678 DNA helicase activity 1/285 74/18639 0.0135135135135135 0.883783783783784 0.680977749985809 0.829407215328068 GO:0031491 nucleosome binding 1/285 74/18639 0.0135135135135135 0.883783783783784 0.680977749985809 0.829407215328068 GO:0035064 methylated histone binding 1/285 74/18639 0.0135135135135135 0.883783783783784 0.680977749985809 0.829407215328068 GO:0061775 cohesin loader activity 2/285 153/18639 0.0130718954248366 0.854901960784314 0.681704560543617 0.829407215328068 GO:0003725 double-stranded RNA binding 1/285 75/18639 0.0133333333333333 0.872 0.68587520978942 0.832746616459504 GO:0004386 helicase activity 2/285 155/18639 0.0129032258064516 0.843870967741935 0.688573713947812 0.833403892062553 GO:0017022 myosin binding 1/285 76/18639 0.0131578947368421 0.860526315789474 0.690697746161431 0.833403892062553 GO:0140034 methylation-dependent protein binding 1/285 76/18639 0.0131578947368421 0.860526315789474 0.690697746161431 0.833403892062553 GO:0003724 RNA helicase activity 1/285 77/18639 0.012987012987013 0.849350649350649 0.695446501338072 0.837403622229761 GO:0140658 ATP-dependent chromatin remodeler activity 2/285 158/18639 0.0126582278481013 0.827848101265823 0.698649117100767 0.838789777938757 GO:0015631 tubulin binding 5/285 385/18639 0.012987012987013 0.849350649350649 0.704260634832929 0.838789777938757 GO:0008186 ATP-dependent activity, acting on RNA 1/285 79/18639 0.0126582278481013 0.827848101265823 0.704727150546742 0.838789777938757 GO:0015370 solute:sodium symporter activity 1/285 79/18639 0.0126582278481013 0.827848101265823 0.704727150546742 0.838789777938757 GO:0046332 SMAD binding 1/285 79/18639 0.0126582278481013 0.827848101265823 0.704727150546742 0.838789777938757 GO:0003689 DNA clamp loader activity 2/285 160/18639 0.0125 0.8175 0.705215378369743 0.838789777938757 GO:0015101 organic cation transmembrane transporter activity 1/285 81/18639 0.0123456790123457 0.807407407407407 0.713725952941902 0.847186903492014 GO:0140713 histone chaperone activity 2/285 164/18639 0.0121951219512195 0.797560975609756 0.717991336935764 0.85052117803344 GO:0015103 inorganic anion transmembrane transporter activity 2/285 165/18639 0.0121212121212121 0.792727272727273 0.721111899967419 0.852488561904803 GO:0004527 exonuclease activity 1/285 84/18639 0.0119047619047619 0.778571428571429 0.726714283148717 0.855647462417037 GO:0004860 protein kinase inhibitor activity 1/285 84/18639 0.0119047619047619 0.778571428571429 0.726714283148717 0.855647462417037 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/285 86/18639 0.0116279069767442 0.76046511627907 0.735045227721407 0.863715116678676 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/285 89/18639 0.0112359550561798 0.734831460674157 0.747069486525427 0.87432581188547 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/285 89/18639 0.0112359550561798 0.734831460674157 0.747069486525427 0.87432581188547 GO:0019210 kinase inhibitor activity 1/285 90/18639 0.0111111111111111 0.726666666666667 0.7509554809373 0.875365271192382 GO:0140793 histone H2AXY142 phosphatase activity 1/285 90/18639 0.0111111111111111 0.726666666666667 0.7509554809373 0.875365271192382 GO:0003713 transcription coactivator activity 3/285 256/18639 0.01171875 0.76640625 0.753345880018709 0.876402378348458 GO:0140097 catalytic activity, acting on DNA 4/285 336/18639 0.0119047619047619 0.778571428571429 0.758515999433296 0.880662711071659 GO:0140297 DNA-binding transcription factor binding 6/285 488/18639 0.0122950819672131 0.804098360655738 0.760062490243719 0.880707329964945 GO:0051213 dioxygenase activity 1/285 93/18639 0.010752688172043 0.703225806451613 0.762260095500601 0.881504744103666 GO:0016410 N-acyltransferase activity 1/285 94/18639 0.0106382978723404 0.695744680851064 0.765913490991938 0.882241438528076 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/285 181/18639 0.0110497237569061 0.722651933701657 0.767197940212525 0.882241438528076 GO:0016887 ATP hydrolysis activity 5/285 417/18639 0.0119904076738609 0.784172661870504 0.767429196527847 0.882241438528076 GO:0003712 transcription coregulator activity 6/285 495/18639 0.0121212121212121 0.792727272727273 0.771798831777737 0.88552164589037 GO:1901981 phosphatidylinositol phosphate binding 2/285 185/18639 0.0108108108108108 0.707027027027027 0.777636500118215 0.888232024842493 GO:0004725 protein tyrosine phosphatase activity 1/285 98/18639 0.0102040816326531 0.66734693877551 0.779976061855862 0.888232024842493 GO:0005249 voltage-gated potassium channel activity 1/285 98/18639 0.0102040816326531 0.66734693877551 0.779976061855862 0.888232024842493 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 3/285 268/18639 0.0111940298507463 0.732089552238806 0.780244912233217 0.888232024842493 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 4/285 349/18639 0.0114613180515759 0.749570200573066 0.783932194484331 0.890693388285699 GO:0043130 ubiquitin binding 1/285 100/18639 0.01 0.654 0.786688379808566 0.892089347200393 GO:0001217 DNA-binding transcription repressor activity 3/285 278/18639 0.0107913669064748 0.705755395683453 0.800780287091837 0.906309472212466 GO:0004497 monooxygenase activity 1/285 106/18639 0.00943396226415094 0.616981132075472 0.805625415729832 0.910029483145497 GO:0019888 protein phosphatase regulator activity 1/285 107/18639 0.00934579439252336 0.611214953271028 0.808614503115414 0.91144181806051 GO:0031267 small GTPase binding 3/285 283/18639 0.0106007067137809 0.693286219081272 0.810432746834546 0.91144181806051 GO:0004843 cysteine-type deubiquitinase activity 1/285 108/18639 0.00925925925925926 0.605555555555556 0.811557783204563 0.91144181806051 GO:1902936 phosphatidylinositol bisphosphate binding 1/285 111/18639 0.00900900900900901 0.589189189189189 0.820119722179739 0.919289669391493 GO:0017124 SH3 domain binding 1/285 115/18639 0.00869565217391304 0.568695652173913 0.830935580913566 0.927325211793766 GO:0101005 deubiquitinase activity 1/285 115/18639 0.00869565217391304 0.568695652173913 0.830935580913566 0.927325211793766 GO:0004518 nuclease activity 2/285 209/18639 0.00956937799043062 0.625837320574163 0.832052073595777 0.927325211793766 GO:0019208 phosphatase regulator activity 1/285 117/18639 0.00854700854700855 0.558974358974359 0.83609796256219 0.930059447878703 GO:0032182 ubiquitin-like protein binding 1/285 120/18639 0.00833333333333333 0.545 0.843548472543262 0.935678826111292 GO:0003697 single-stranded DNA binding 1/285 121/18639 0.00826446280991736 0.540495867768595 0.845956198949935 0.935678826111292 GO:0004540 RNA nuclease activity 1/285 121/18639 0.00826446280991736 0.540495867768595 0.845956198949935 0.935678826111292 GO:0005267 potassium channel activity 1/285 124/18639 0.00806451612903226 0.52741935483871 0.852960071411413 0.941642120423942 GO:0004519 endonuclease activity 1/285 127/18639 0.0078740157480315 0.51496062992126 0.859646567030004 0.945449331724148 GO:0019783 ubiquitin-like protein peptidase activity 1/285 127/18639 0.0078740157480315 0.51496062992126 0.859646567030004 0.945449331724148 GO:0031490 chromatin DNA binding 1/285 128/18639 0.0078125 0.5109375 0.86180736696499 0.945883091192504 GO:0051020 GTPase binding 3/285 315/18639 0.00952380952380952 0.622857142857143 0.863280286995898 0.945883091192504 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/285 130/18639 0.00769230769230769 0.503076923076923 0.866030019227222 0.947118972338385 GO:0005262 calcium channel activity 1/285 131/18639 0.00763358778625954 0.499236641221374 0.868092877540488 0.947376524834604 GO:0000287 magnesium ion binding 2/285 230/18639 0.00869565217391304 0.568695652173913 0.869509961149568 0.947376524834604 GO:0016779 nucleotidyltransferase activity 1/285 136/18639 0.00735294117647059 0.480882352941176 0.877941930262554 0.951239494013602 GO:0099094 ligand-gated monoatomic cation channel activity 1/285 136/18639 0.00735294117647059 0.480882352941176 0.877941930262554 0.951239494013602 GO:0140789 histone phosphatase activity 1/285 136/18639 0.00735294117647059 0.480882352941176 0.877941930262554 0.951239494013602 GO:0016922 nuclear receptor binding 1/285 137/18639 0.0072992700729927 0.477372262773723 0.879821979437021 0.951511177761519 GO:0022843 voltage-gated monoatomic cation channel activity 1/285 143/18639 0.00699300699300699 0.457342657342657 0.890511469411325 0.96129149378228 GO:0003774 cytoskeletal motor activity 1/285 153/18639 0.0065359477124183 0.427450980392157 0.90626282477737 0.97623740231235 GO:0141003 histone H2AX kinase activity 3/285 354/18639 0.00847457627118644 0.554237288135593 0.909896958144385 0.97623740231235 GO:0003730 mRNA 3'-UTR binding 2/285 262/18639 0.00763358778625954 0.499236641221374 0.912076893033867 0.97623740231235 GO:0140996 histone H3 kinase activity 3/285 357/18639 0.00840336134453781 0.549579831932773 0.912807657598205 0.97623740231235 GO:0035173 histone kinase activity 3/285 360/18639 0.00833333333333333 0.545 0.915632951131553 0.97623740231235 GO:0015079 potassium ion transmembrane transporter activity 1/285 160/18639 0.00625 0.40875 0.915924348451093 0.97623740231235 GO:0046873 metal ion transmembrane transporter activity 4/285 450/18639 0.00888888888888889 0.581333333333333 0.916058384361589 0.97623740231235 GO:0008514 organic anion transmembrane transporter activity 2/285 269/18639 0.00743494423791822 0.486245353159851 0.919470310167003 0.976661217384429 GO:0015081 sodium ion transmembrane transporter activity 1/285 164/18639 0.00609756097560976 0.398780487804878 0.920992752463361 0.976661217384429 GO:0005096 GTPase activator activity 2/285 271/18639 0.00738007380073801 0.482656826568266 0.921473169141815 0.976661217384429 GO:0016791 phosphatase activity 2/285 273/18639 0.00732600732600733 0.479120879120879 0.92342919579497 0.976961323087432 GO:0005244 voltage-gated monoatomic ion channel activity 1/285 173/18639 0.00578034682080925 0.378034682080925 0.931310882483291 0.981238258075264 GO:0004721 phosphoprotein phosphatase activity 1/285 175/18639 0.00571428571428571 0.373714285714286 0.933414841281956 0.981238258075264 GO:0022832 voltage-gated channel activity 1/285 175/18639 0.00571428571428571 0.373714285714286 0.933414841281956 0.981238258075264 GO:0004252 serine-type endopeptidase activity 1/285 176/18639 0.00568181818181818 0.371590909090909 0.934442612633485 0.981238258075264 GO:0015291 secondary active transmembrane transporter activity 2/285 287/18639 0.00696864111498258 0.455749128919861 0.935890755228187 0.981238258075264 GO:0140098 catalytic activity, acting on RNA 3/285 387/18639 0.00775193798449612 0.506976744186047 0.937552993160954 0.981238258075264 GO:0015276 ligand-gated monoatomic ion channel activity 1/285 186/18639 0.00537634408602151 0.351612903225806 0.943889604474142 0.983499238512687 GO:0022834 ligand-gated channel activity 1/285 188/18639 0.00531914893617021 0.347872340425532 0.945609476380142 0.983499238512687 GO:0046943 carboxylic acid transmembrane transporter activity 1/285 188/18639 0.00531914893617021 0.347872340425532 0.945609476380142 0.983499238512687 GO:0005342 organic acid transmembrane transporter activity 1/285 189/18639 0.00529100529100529 0.346031746031746 0.946449609664607 0.983499238512687 GO:0008236 serine-type peptidase activity 1/285 194/18639 0.00515463917525773 0.337113402061856 0.950460216354546 0.985912551245213 GO:0017171 serine hydrolase activity 1/285 198/18639 0.00505050505050505 0.33030303030303 0.953452042762966 0.986990731957928 GO:0016829 lyase activity 1/285 200/18639 0.005 0.327 0.954879732116831 0.986990731957928 GO:0004674 protein serine/threonine kinase activity 3/285 433/18639 0.0069284064665127 0.453117782909931 0.963212553453427 0.993844754800003 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/285 229/18639 0.00436681222707424 0.285589519650655 0.971289852223048 0.996365783622618 GO:0005085 guanyl-nucleotide exchange factor activity 1/285 230/18639 0.00434782608695652 0.284347826086957 0.971734305895858 0.996365783622618 GO:0061630 ubiquitin protein ligase activity 2/285 353/18639 0.0056657223796034 0.370538243626062 0.972848892783254 0.996365783622618 GO:0061659 ubiquitin-like protein ligase activity 2/285 372/18639 0.00537634408602151 0.351612903225806 0.978919345125424 0.996365783622618 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3/285 484/18639 0.00619834710743802 0.405371900826446 0.979967323179071 0.996365783622618 GO:0005525 GTP binding 2/285 378/18639 0.00529100529100529 0.346031746031746 0.98054750877968 0.996365783622618 GO:0030695 GTPase regulator activity 3/285 489/18639 0.00613496932515337 0.401226993865031 0.981146264463025 0.996365783622618 GO:0060589 nucleoside-triphosphatase regulator activity 3/285 490/18639 0.00612244897959184 0.400408163265306 0.981373993377013 0.996365783622618 GO:0001216 DNA-binding transcription activator activity 3/285 491/18639 0.00610997963340122 0.39959266802444 0.981599102641946 0.996365783622618 GO:0019001 guanyl nucleotide binding 2/285 400/18639 0.005 0.327 0.985539166674841 0.996365783622618 GO:0032561 guanyl ribonucleotide binding 2/285 400/18639 0.005 0.327 0.985539166674841 0.996365783622618 GO:0004842 ubiquitin-protein transferase activity 2/285 449/18639 0.0044543429844098 0.291314031180401 0.992598365443905 0.996365783622618 GO:0022836 gated channel activity 1/285 318/18639 0.00314465408805031 0.205660377358491 0.992862693967252 0.996365783622618 GO:0030371 translation repressor activity 1/285 329/18639 0.00303951367781155 0.198784194528875 0.993993585763762 0.996365783622618 GO:0003924 GTPase activity 1/285 331/18639 0.00302114803625378 0.197583081570997 0.994179118428904 0.996365783622618 GO:0019787 ubiquitin-like protein transferase activity 2/285 479/18639 0.00417536534446764 0.273068893528184 0.995115814091481 0.996365783622618 GO:0016755 aminoacyltransferase activity 2/285 496/18639 0.00403225806451613 0.263709677419355 0.996147524148251 0.996365783622618 GO:0106310 protein serine kinase activity 1/285 361/18639 0.00277008310249307 0.181163434903047 0.996365783622618 0.996365783622618