ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 42/846 175/18639 0.24 5.28765957446808 2.49360723654671e-19 2.48612641483707e-16 GO:0023026 MHC class II protein complex binding 11/846 27/18639 0.407407407407407 8.97596532702916 1.05581735898118e-08 5.26324953452118e-06 GO:0042605 peptide antigen binding 13/846 45/18639 0.288888888888889 6.36477541371158 5.99131594775187e-08 1.99111399996954e-05 GO:0005201 extracellular matrix structural constituent 25/846 168/18639 0.148809523809524 3.2785587639311 1.63961051108251e-07 4.08672919887316e-05 GO:0042277 peptide binding 31/846 249/18639 0.124497991967871 2.74292916346236 3.56030296512871e-07 7.09924411246665e-05 GO:0023023 MHC protein complex binding 11/846 37/18639 0.297297297297297 6.55002875215641 4.56192016135126e-07 7.58039066811201e-05 GO:0009055 electron transfer activity 19/846 116/18639 0.163793103448276 3.60867571533382 1.12350521698632e-06 0.000160019243047909 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 14/846 68/18639 0.205882352941176 4.53598247809762 1.77334980061731e-06 0.000221003718901932 GO:0031994 insulin-like growth factor I binding 6/846 13/18639 0.461538461538462 10.1685761047463 1.12028603643923e-05 0.00124102797592213 GO:0005518 collagen binding 13/846 72/18639 0.180555555555556 3.97798463356974 1.87113789730927e-05 0.00186552448361735 GO:0003954 NADH dehydrogenase activity 10/846 44/18639 0.227272727272727 5.00725338491296 2.13989565006296e-05 0.00193952360282979 GO:0140375 immune receptor activity 20/846 156/18639 0.128205128205128 2.82460447354064 2.70111426010729e-05 0.00224417576443914 GO:0032395 MHC class II receptor activity 5/846 10/18639 0.5 11.0159574468085 3.96430847576764e-05 0.00297844485548113 GO:0001968 fibronectin binding 8/846 30/18639 0.266666666666667 5.87517730496454 4.18236990739577e-05 0.00297844485548113 GO:0008137 NADH dehydrogenase (ubiquinone) activity 9/846 41/18639 0.219512195121951 4.83627400103788 7.40269583164624e-05 0.00492032516276753 GO:0005520 insulin-like growth factor binding 6/846 19/18639 0.315789473684211 6.95744680851064 0.000140094758013919 0.00872965460874233 GO:0016651 oxidoreductase activity, acting on NAD(P)H 13/846 88/18639 0.147727272727273 3.25471470019342 0.000162342966742764 0.00952093752014916 GO:0043394 proteoglycan binding 8/846 37/18639 0.216216216216216 4.76365727429557 0.000208125319146843 0.0114603584770944 GO:0016504 peptidase activator activity 10/846 57/18639 0.175438596491228 3.86524822695035 0.000218402017116142 0.0114603584770944 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 10/846 58/18639 0.172413793103448 3.79860601614087 0.000253318871390211 0.012627945738802 GO:0030021 extracellular matrix structural constituent conferring compression resistance 6/846 22/18639 0.272727272727273 6.00870406189555 0.000342785343167834 0.0162741422446824 GO:0071813 lipoprotein particle binding 7/846 32/18639 0.21875 4.81948138297872 0.000481268313383766 0.0208619351497224 GO:0071814 protein-lipid complex binding 7/846 32/18639 0.21875 4.81948138297872 0.000481268313383766 0.0208619351497224 GO:0019843 rRNA binding 10/846 65/18639 0.153846153846154 3.38952536824877 0.00065289999828287 0.0271225540953342 GO:0005539 glycosaminoglycan binding 23/846 242/18639 0.0950413223140496 2.09394232459996 0.000687421012004782 0.0274143499587507 GO:0050840 extracellular matrix binding 10/846 67/18639 0.149253731343284 3.28834550651 0.000833658415070065 0.0319675938394175 GO:0022853 active monoatomic ion transmembrane transporter activity 14/846 118/18639 0.11864406779661 2.61395600432744 0.000922347760028022 0.0340585450647384 GO:0003823 antigen binding 18/846 174/18639 0.103448275862069 2.27916360968452 0.000968176269641612 0.034200212231483 GO:0070064 proline-rich region binding 5/846 18/18639 0.277777777777778 6.11997635933806 0.000994790526291881 0.034200212231483 GO:1990948 ubiquitin ligase inhibitor activity 4/846 11/18639 0.363636363636364 8.01160541586074 0.00107637217209759 0.0357714351860432 GO:0019838 growth factor binding 15/846 136/18639 0.110294117647059 2.42999061326658 0.00131118353585213 0.0413719869439305 GO:0004896 cytokine receptor activity 12/846 96/18639 0.125 2.75398936170213 0.00132788724393759 0.0413719869439305 GO:0015078 proton transmembrane transporter activity 18/846 185/18639 0.0972972972972973 2.14364577343301 0.00194170031875169 0.0586628853877404 GO:0072542 protein phosphatase activator activity 5/846 21/18639 0.238095238095238 5.24569402228977 0.00210985967048358 0.0600551008461879 GO:0008201 heparin binding 17/846 172/18639 0.0988372093023256 2.17757298367145 0.00216591736238848 0.0600551008461879 GO:0008035 high-density lipoprotein particle binding 4/846 13/18639 0.307692307692308 6.77905073649755 0.00216848909775603 0.0600551008461879 GO:0038024 cargo receptor activity 9/846 65/18639 0.138461538461538 3.0505728314239 0.00255777431365311 0.0689216483976258 GO:0061133 endopeptidase activator activity 5/846 22/18639 0.227272727272727 5.00725338491296 0.00262958741381175 0.0689920697781662 GO:0061134 peptidase regulator activity 20/846 226/18639 0.0884955752212389 1.94972698173602 0.00344464436256839 0.0880592417815561 GO:0015399 primary active transmembrane transporter activity 16/846 166/18639 0.0963855421686747 2.12355806203538 0.00369899316884194 0.0913982773873674 GO:0004129 cytochrome-c oxidase activity 4/846 15/18639 0.266666666666667 5.87517730496454 0.00385027848572661 0.0913982773873674 GO:0055105 ubiquitin-protein transferase inhibitor activity 4/846 15/18639 0.266666666666667 5.87517730496454 0.00385027848572661 0.0913982773873674 GO:0001540 amyloid-beta binding 10/846 83/18639 0.120481927710843 2.65444757754422 0.00427071952602007 0.0990211015684189 GO:0019211 phosphatase activator activity 5/846 25/18639 0.2 4.4063829787234 0.00474041402770457 0.102844029035367 GO:0004857 enzyme inhibitor activity 31/846 416/18639 0.0745192307692308 1.6418013502455 0.0048446860232284 0.102844029035367 GO:0008142 oxysterol binding 4/846 16/18639 0.25 5.50797872340426 0.00495136749618617 0.102844029035367 GO:0016675 oxidoreductase activity, acting on a heme group of donors 4/846 16/18639 0.25 5.50797872340426 0.00495136749618617 0.102844029035367 GO:0055102 lipase inhibitor activity 4/846 16/18639 0.25 5.50797872340426 0.00495136749618617 0.102844029035367 GO:0016209 antioxidant activity 10/846 86/18639 0.116279069767442 2.56185056902524 0.00550760472704294 0.112062896180853 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 3/846 10/18639 0.3 6.60957446808511 0.0087977310110064 0.162432181814322 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 3/846 10/18639 0.3 6.60957446808511 0.0087977310110064 0.162432181814322 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 3/846 10/18639 0.3 6.60957446808511 0.0087977310110064 0.162432181814322 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 3/846 10/18639 0.3 6.60957446808511 0.0087977310110064 0.162432181814322 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 3/846 10/18639 0.3 6.60957446808511 0.0087977310110064 0.162432181814322 GO:0033218 amide binding 20/846 247/18639 0.0809716599190283 1.78396072013093 0.00907586599505694 0.164520698128578 GO:0051287 NAD binding 7/846 54/18639 0.12962962962963 2.8559889676911 0.0106931178194185 0.183607026348174 GO:0016408 C-acyltransferase activity 4/846 20/18639 0.2 4.4063829787234 0.0114129333685846 0.183607026348174 GO:0032934 sterol binding 8/846 68/18639 0.117647058823529 2.59198998748436 0.0116128863681694 0.183607026348174 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 3/846 11/18639 0.272727272727273 6.00870406189555 0.0116932405755972 0.183607026348174 GO:0042608 T cell receptor binding 3/846 11/18639 0.272727272727273 6.00870406189555 0.0116932405755972 0.183607026348174 GO:0050786 RAGE receptor binding 3/846 11/18639 0.272727272727273 6.00870406189555 0.0116932405755972 0.183607026348174 GO:0050998 nitric-oxide synthase binding 3/846 11/18639 0.272727272727273 6.00870406189555 0.0116932405755972 0.183607026348174 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 3/846 11/18639 0.272727272727273 6.00870406189555 0.0116932405755972 0.183607026348174 GO:0140313 molecular sequestering activity 7/846 55/18639 0.127272727272727 2.80406189555126 0.0117862083112168 0.183607026348174 GO:0019903 protein phosphatase binding 13/846 144/18639 0.0902777777777778 1.98899231678487 0.0140765816632156 0.205846945850717 GO:0019955 cytokine binding 13/846 144/18639 0.0902777777777778 1.98899231678487 0.0140765816632156 0.205846945850717 GO:1901681 sulfur compound binding 21/846 275/18639 0.0763636363636364 1.68243713733075 0.0141995896544388 0.205846945850717 GO:0004601 peroxidase activity 7/846 57/18639 0.12280701754386 2.70567375886525 0.0142106457245476 0.205846945850717 GO:0005178 integrin binding 14/846 161/18639 0.0869565217391304 1.91581868640148 0.0150479773171984 0.205846945850717 GO:0043021 ribonucleoprotein complex binding 15/846 177/18639 0.0847457627118644 1.86711143166246 0.0150693146496527 0.205846945850717 GO:0004859 phospholipase inhibitor activity 3/846 12/18639 0.25 5.50797872340426 0.0150720431766322 0.205846945850717 GO:0097371 MDM2/MDM4 family protein binding 3/846 12/18639 0.25 5.50797872340426 0.0150720431766322 0.205846945850717 GO:0141221 histone deacetylase activity, hydrolytic mechanism 3/846 12/18639 0.25 5.50797872340426 0.0150720431766322 0.205846945850717 GO:0004407 histone deacetylase activity 4/846 22/18639 0.181818181818182 4.00580270793037 0.0160401817684456 0.213227482975204 GO:0033558 protein lysine deacetylase activity 4/846 22/18639 0.181818181818182 4.00580270793037 0.0160401817684456 0.213227482975204 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/846 59/18639 0.11864406779661 2.61395600432744 0.0169717130156332 0.222642077323504 GO:0004602 glutathione peroxidase activity 4/846 23/18639 0.173913043478261 3.83163737280296 0.0187357748133267 0.241388515793935 GO:0005504 fatty acid binding 6/846 47/18639 0.127659574468085 2.81258488003622 0.0188849591092547 0.241388515793935 GO:0061135 endopeptidase regulator activity 15/846 184/18639 0.0815217391304348 1.79608001850139 0.0207001618228574 0.261241282751757 GO:0008191 metalloendopeptidase inhibitor activity 3/846 14/18639 0.214285714285714 4.72112462006079 0.0233109491673858 0.286166154369402 GO:0044548 S100 protein binding 3/846 14/18639 0.214285714285714 4.72112462006079 0.0233109491673858 0.286166154369402 GO:0019888 protein phosphatase regulator activity 10/846 107/18639 0.0934579439252336 2.05905746669318 0.0235362333583661 0.286166154369402 GO:0120020 cholesterol transfer activity 4/846 25/18639 0.16 3.52510638297872 0.0249250368164612 0.299400743445926 GO:0003743 translation initiation factor activity 6/846 51/18639 0.117647058823529 2.59198998748436 0.0272288648499389 0.322393102304133 GO:0160215 deacylase activity 7/846 65/18639 0.107692307692308 2.37266775777414 0.0274858713097806 0.322393102304133 GO:0141050 histone H3K deacetylase activity 3/846 15/18639 0.2 4.4063829787234 0.0281761168378006 0.322544643143877 GO:0141051 histone H4K deacetylase activity 3/846 15/18639 0.2 4.4063829787234 0.0281761168378006 0.322544643143877 GO:0048306 calcium-dependent protein binding 8/846 80/18639 0.1 2.2031914893617 0.0284693366064806 0.322544643143877 GO:0005543 phospholipid binding 32/846 497/18639 0.0643863179074447 1.41855387645019 0.0300854141883621 0.334805226867897 GO:0001618 virus receptor activity 8/846 81/18639 0.0987654320987654 2.17599159443131 0.0303829473972686 0.334805226867897 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 5/846 39/18639 0.128205128205128 2.82460447354064 0.0305589525024861 0.334805226867897 GO:0140272 exogenous protein binding 8/846 82/18639 0.0975609756097561 2.14945511157239 0.0323829909715657 0.350933065202728 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/846 16/18639 0.1875 4.13098404255319 0.0335356743781732 0.357072534910923 GO:0050997 quaternary ammonium group binding 5/846 40/18639 0.125 2.75398936170213 0.0336658157288132 0.357072534910923 GO:0008135 translation factor activity, RNA binding 8/846 83/18639 0.0963855421686747 2.12355806203538 0.0344709572819418 0.361763625369431 GO:0015485 cholesterol binding 6/846 54/18639 0.111111111111111 2.44799054373522 0.0348777449504557 0.362219913704212 GO:0002039 p53 binding 7/846 69/18639 0.101449275362319 2.23512180080173 0.0365391202636959 0.372839926021107 GO:0180051 translation factor activity 8/846 84/18639 0.0952380952380952 2.09827760891591 0.0366482575226364 0.372839926021107 GO:0030169 low-density lipoprotein particle binding 3/846 17/18639 0.176470588235294 3.88798498122653 0.0393836155917462 0.376893333776108 GO:0038191 neuropilin binding 3/846 17/18639 0.176470588235294 3.88798498122653 0.0393836155917462 0.376893333776108 GO:0048038 quinone binding 3/846 17/18639 0.176470588235294 3.88798498122653 0.0393836155917462 0.376893333776108 GO:1990226 histone methyltransferase binding 3/846 17/18639 0.176470588235294 3.88798498122653 0.0393836155917462 0.376893333776108 GO:0019208 phosphatase regulator activity 10/846 117/18639 0.0854700854700855 1.8830696490271 0.0401567081064969 0.376893333776108 GO:0008307 structural constituent of muscle 5/846 42/18639 0.119047619047619 2.62284701114488 0.0404489335145873 0.376893333776108 GO:0016859 cis-trans isomerase activity 5/846 42/18639 0.119047619047619 2.62284701114488 0.0404489335145873 0.376893333776108 GO:0035198 miRNA binding 5/846 42/18639 0.119047619047619 2.62284701114488 0.0404489335145873 0.376893333776108 GO:0042056 chemoattractant activity 5/846 42/18639 0.119047619047619 2.62284701114488 0.0404489335145873 0.376893333776108 GO:0008200 ion channel inhibitor activity 5/846 43/18639 0.116279069767442 2.56185056902524 0.0441288461269617 0.396296699572674 GO:0048156 tau protein binding 5/846 43/18639 0.116279069767442 2.56185056902524 0.0441288461269617 0.396296699572674 GO:0003712 transcription coregulator activity 31/846 495/18639 0.0626262626262626 1.37977648828713 0.0442944604454489 0.396296699572674 GO:0003713 transcription coactivator activity 18/846 256/18639 0.0703125 1.54911901595745 0.0443688179258474 0.396296699572674 GO:0031210 phosphatidylcholine binding 4/846 30/18639 0.133333333333333 2.93758865248227 0.0452420230861745 0.396296699572674 GO:0003714 transcription corepressor activity 15/846 204/18639 0.0735294117647059 1.61999374217772 0.0455063957772758 0.396296699572674 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 3/846 18/18639 0.166666666666667 3.67198581560284 0.045711254213498 0.396296699572674 GO:0035615 clathrin adaptor activity 3/846 18/18639 0.166666666666667 3.67198581560284 0.045711254213498 0.396296699572674 GO:0061980 regulatory RNA binding 6/846 58/18639 0.103448275862069 2.27916360968452 0.0470469795799926 0.403618230998512 GO:0004521 RNA endonuclease activity 7/846 73/18639 0.0958904109589041 2.11264937336054 0.0473654293147702 0.403618230998512 GO:0016248 channel inhibitor activity 5/846 44/18639 0.113636363636364 2.50362669245648 0.0480026933874788 0.405582078875563 GO:0004540 RNA nuclease activity 10/846 121/18639 0.0826446280991736 1.82081941269562 0.0486287167775148 0.407418744766237 GO:0070325 lipoprotein particle receptor binding 4/846 31/18639 0.129032258064516 2.84282772820865 0.0501490578115509 0.416655088650969 GO:0141110 transporter inhibitor activity 5/846 45/18639 0.111111111111111 2.44799054373522 0.0520712017332461 0.425610209382919 GO:0045296 cadherin binding 22/846 334/18639 0.0658682634730539 1.45120397502867 0.0521528075494456 0.425610209382919 GO:0050145 nucleoside monophosphate kinase activity 3/846 19/18639 0.157894736842105 3.47872340425532 0.0525075784895677 0.425610209382919 GO:0030246 carbohydrate binding 19/846 280/18639 0.0678571428571429 1.49502279635258 0.0532515178165556 0.42815938115408 GO:0120015 sterol transfer activity 4/846 32/18639 0.125 2.75398936170213 0.055336016083842 0.441360064284724 GO:0030276 clathrin binding 5/846 46/18639 0.108695652173913 2.39477335800185 0.0563346676425328 0.445759235234962 GO:0005496 steroid binding 9/846 108/18639 0.0833333333333333 1.83599290780142 0.0569441148352602 0.447033720399641 GO:0000339 RNA cap binding 3/846 20/18639 0.15 3.30478723404255 0.0597595746873883 0.454811419567375 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 3/846 20/18639 0.15 3.30478723404255 0.0597595746873883 0.454811419567375 GO:0031418 L-ascorbic acid binding 3/846 20/18639 0.15 3.30478723404255 0.0597595746873883 0.454811419567375 GO:0043024 ribosomal small subunit binding 3/846 20/18639 0.15 3.30478723404255 0.0597595746873883 0.454811419567375 GO:0044389 ubiquitin-like protein ligase binding 21/846 322/18639 0.0652173913043478 1.43686401480111 0.061706150852413 0.466068427271634 GO:0032266 phosphatidylinositol-3-phosphate binding 5/846 48/18639 0.104166666666667 2.29499113475177 0.0654455615124727 0.486973380869763 GO:1902936 phosphatidylinositol bisphosphate binding 9/846 111/18639 0.0810810810810811 1.78637147786084 0.0654507853927265 0.486973380869763 GO:0033293 monocarboxylic acid binding 7/846 79/18639 0.0886075949367089 1.95219499057366 0.0670952796135573 0.494486501878867 GO:0140312 cargo adaptor activity 3/846 21/18639 0.142857142857143 3.14741641337386 0.0674525218209889 0.494486501878867 GO:0000182 rDNA binding 2/846 10/18639 0.2 4.4063829787234 0.072708214042715 0.506923702102006 GO:0008239 dipeptidyl-peptidase activity 2/846 10/18639 0.2 4.4063829787234 0.072708214042715 0.506923702102006 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 2/846 10/18639 0.2 4.4063829787234 0.072708214042715 0.506923702102006 GO:0016868 intramolecular phosphotransferase activity 2/846 10/18639 0.2 4.4063829787234 0.072708214042715 0.506923702102006 GO:0030957 Tat protein binding 2/846 10/18639 0.2 4.4063829787234 0.072708214042715 0.506923702102006 GO:0031720 haptoglobin binding 2/846 10/18639 0.2 4.4063829787234 0.072708214042715 0.506923702102006 GO:1990763 arrestin family protein binding 2/846 10/18639 0.2 4.4063829787234 0.072708214042715 0.506923702102006 GO:0120013 lipid transfer activity 6/846 65/18639 0.0923076923076923 2.03371522094926 0.073982747327695 0.511213443657825 GO:0003779 actin binding 27/846 443/18639 0.0609480812641084 1.34280293934009 0.0743489963193427 0.511213443657825 GO:0055106 ubiquitin-protein transferase regulator activity 4/846 36/18639 0.111111111111111 2.44799054373522 0.0788244215186188 0.535539459881595 GO:1901981 phosphatidylinositol phosphate binding 13/846 185/18639 0.0702702702702703 1.54818861414606 0.0789611841550596 0.535539459881595 GO:0051020 GTPase binding 20/846 315/18639 0.0634920634920635 1.39885173927727 0.0825929563040624 0.547823539772622 GO:0031406 carboxylic acid binding 13/846 187/18639 0.0695187165775401 1.53163044714985 0.084220732491024 0.547823539772622 GO:0140297 DNA-binding transcription factor binding 29/846 488/18639 0.0594262295081967 1.30927363097314 0.0846878816735114 0.547823539772622 GO:0019213 deacetylase activity 4/846 37/18639 0.108108108108108 2.38182863714779 0.0853604581348964 0.547823539772622 GO:0008199 ferric iron binding 2/846 11/18639 0.181818181818182 4.00580270793037 0.0862670970354078 0.547823539772622 GO:0008432 JUN kinase binding 2/846 11/18639 0.181818181818182 4.00580270793037 0.0862670970354078 0.547823539772622 GO:0019107 myristoyltransferase activity 2/846 11/18639 0.181818181818182 4.00580270793037 0.0862670970354078 0.547823539772622 GO:0019864 IgG binding 2/846 11/18639 0.181818181818182 4.00580270793037 0.0862670970354078 0.547823539772622 GO:0032050 clathrin heavy chain binding 2/846 11/18639 0.181818181818182 4.00580270793037 0.0862670970354078 0.547823539772622 GO:0097493 structural molecule activity conferring elasticity 2/846 11/18639 0.181818181818182 4.00580270793037 0.0862670970354078 0.547823539772622 GO:0043177 organic acid binding 13/846 189/18639 0.0687830687830688 1.51542271755038 0.0896963165740577 0.565995111546427 GO:0042162 telomeric DNA binding 4/846 38/18639 0.105263157894737 2.31914893617021 0.0921512528965103 0.576486035831445 GO:0019902 phosphatase binding 13/846 190/18639 0.068421052631579 1.50744680851064 0.0925153116680353 0.576486035831445 GO:0035091 phosphatidylinositol binding 18/846 284/18639 0.0633802816901408 1.39638897213066 0.0968752614329264 0.595524445353596 GO:0017069 snRNA binding 5/846 54/18639 0.0925925925925926 2.03999211977935 0.0973625723095649 0.595524445353596 GO:0050661 NADP binding 5/846 54/18639 0.0925925925925926 2.03999211977935 0.0973625723095649 0.595524445353596 GO:0000340 RNA 7-methylguanosine cap binding 2/846 12/18639 0.166666666666667 3.67198581560284 0.100506107807163 0.599924120315275 GO:0005095 GTPase inhibitor activity 2/846 12/18639 0.166666666666667 3.67198581560284 0.100506107807163 0.599924120315275 GO:0031543 peptidyl-proline dioxygenase activity 2/846 12/18639 0.166666666666667 3.67198581560284 0.100506107807163 0.599924120315275 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/846 12/18639 0.166666666666667 3.67198581560284 0.100506107807163 0.599924120315275 GO:0008139 nuclear localization sequence binding 3/846 25/18639 0.12 2.64382978723404 0.102293982400799 0.599924120315275 GO:0017056 structural constituent of nuclear pore 3/846 25/18639 0.12 2.64382978723404 0.102293982400799 0.599924120315275 GO:0047617 fatty acyl-CoA hydrolase activity 3/846 25/18639 0.12 2.64382978723404 0.102293982400799 0.599924120315275 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 9/846 122/18639 0.0737704918032787 1.62530519707011 0.103184169591679 0.601605947853242 GO:0016289 acyl-CoA hydrolase activity 3/846 26/18639 0.115384615384615 2.54214402618658 0.111928550575146 0.634049800701255 GO:0019865 immunoglobulin binding 3/846 26/18639 0.115384615384615 2.54214402618658 0.111928550575146 0.634049800701255 GO:0030247 polysaccharide binding 3/846 26/18639 0.115384615384615 2.54214402618658 0.111928550575146 0.634049800701255 GO:0030507 spectrin binding 3/846 26/18639 0.115384615384615 2.54214402618658 0.111928550575146 0.634049800701255 GO:0050750 low-density lipoprotein particle receptor binding 3/846 26/18639 0.115384615384615 2.54214402618658 0.111928550575146 0.634049800701255 GO:0005125 cytokine activity 15/846 234/18639 0.0641025641025641 1.41230223677032 0.11331369148495 0.63826977633048 GO:0005542 folic acid binding 2/846 13/18639 0.153846153846154 3.38952536824877 0.115335743881139 0.638831870274975 GO:0031432 titin binding 2/846 13/18639 0.153846153846154 3.38952536824877 0.115335743881139 0.638831870274975 GO:0035325 Toll-like receptor binding 2/846 13/18639 0.153846153846154 3.38952536824877 0.115335743881139 0.638831870274975 GO:0072341 modified amino acid binding 7/846 91/18639 0.0769230769230769 1.69476268412439 0.119320603032306 0.657252161454193 GO:0005044 scavenger receptor activity 3/846 27/18639 0.111111111111111 2.44799054373522 0.121893277710105 0.664085234300409 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/846 27/18639 0.111111111111111 2.44799054373522 0.121893277710105 0.664085234300409 GO:0004519 endonuclease activity 9/846 127/18639 0.0708661417322835 1.56131680348467 0.123712204811184 0.668889527682619 GO:0043178 alcohol binding 7/846 92/18639 0.0760869565217391 1.6763413506013 0.124417973020019 0.668889527682619 GO:0001786 phosphatidylserine binding 5/846 59/18639 0.0847457627118644 1.86711143166246 0.128921200042321 0.668889527682619 GO:0031593 polyubiquitin modification-dependent protein binding 5/846 59/18639 0.0847457627118644 1.86711143166246 0.128921200042321 0.668889527682619 GO:0005344 oxygen carrier activity 2/846 14/18639 0.142857142857143 3.14741641337386 0.130673209666764 0.668889527682619 GO:0008474 palmitoyl-(protein) hydrolase activity 2/846 14/18639 0.142857142857143 3.14741641337386 0.130673209666764 0.668889527682619 GO:0019763 immunoglobulin receptor activity 2/846 14/18639 0.142857142857143 3.14741641337386 0.130673209666764 0.668889527682619 GO:0019992 diacylglycerol binding 2/846 14/18639 0.142857142857143 3.14741641337386 0.130673209666764 0.668889527682619 GO:0032036 myosin heavy chain binding 2/846 14/18639 0.142857142857143 3.14741641337386 0.130673209666764 0.668889527682619 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/846 14/18639 0.142857142857143 3.14741641337386 0.130673209666764 0.668889527682619 GO:0098599 palmitoyl hydrolase activity 2/846 14/18639 0.142857142857143 3.14741641337386 0.130673209666764 0.668889527682619 GO:0045499 chemorepellent activity 3/846 28/18639 0.107142857142857 2.36056231003039 0.132167740173998 0.668889527682619 GO:0046625 sphingolipid binding 3/846 28/18639 0.107142857142857 2.36056231003039 0.132167740173998 0.668889527682619 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 3/846 28/18639 0.107142857142857 2.36056231003039 0.132167740173998 0.668889527682619 GO:0042562 hormone binding 7/846 94/18639 0.074468085106383 1.64067451335446 0.134937910775057 0.675938274071185 GO:0043022 ribosome binding 8/846 112/18639 0.0714285714285714 1.57370820668693 0.136753601340468 0.675938274071185 GO:0001223 transcription coactivator binding 4/846 44/18639 0.0909090909090909 2.00290135396518 0.137852945987886 0.675938274071185 GO:0019205 nucleobase-containing compound kinase activity 4/846 44/18639 0.0909090909090909 2.00290135396518 0.137852945987886 0.675938274071185 GO:0030020 extracellular matrix structural constituent conferring tensile strength 4/846 44/18639 0.0909090909090909 2.00290135396518 0.137852945987886 0.675938274071185 GO:0030547 signaling receptor inhibitor activity 4/846 44/18639 0.0909090909090909 2.00290135396518 0.137852945987886 0.675938274071185 GO:0019905 syntaxin binding 5/846 61/18639 0.0819672131147541 1.80589466341123 0.142698754654921 0.675938274071185 GO:0004629 phospholipase C activity 3/846 29/18639 0.103448275862069 2.27916360968452 0.142731356756492 0.675938274071185 GO:0051861 glycolipid binding 3/846 29/18639 0.103448275862069 2.27916360968452 0.142731356756492 0.675938274071185 GO:0031625 ubiquitin protein ligase binding 18/846 302/18639 0.0596026490066225 1.31316049034803 0.145655517553244 0.675938274071185 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 9/846 132/18639 0.0681818181818182 1.50217601547389 0.146262671348068 0.675938274071185 GO:0005041 low-density lipoprotein particle receptor activity 2/846 15/18639 0.133333333333333 2.93758865248227 0.146441993178913 0.675938274071185 GO:0005523 tropomyosin binding 2/846 15/18639 0.133333333333333 2.93758865248227 0.146441993178913 0.675938274071185 GO:0010181 FMN binding 2/846 15/18639 0.133333333333333 2.93758865248227 0.146441993178913 0.675938274071185 GO:0017081 chloride channel regulator activity 2/846 15/18639 0.133333333333333 2.93758865248227 0.146441993178913 0.675938274071185 GO:0031386 protein tag activity 2/846 15/18639 0.133333333333333 2.93758865248227 0.146441993178913 0.675938274071185 GO:0051371 muscle alpha-actinin binding 2/846 15/18639 0.133333333333333 2.93758865248227 0.146441993178913 0.675938274071185 GO:0061578 K63-linked deubiquitinase activity 2/846 15/18639 0.133333333333333 2.93758865248227 0.146441993178913 0.675938274071185 GO:0141047 molecular tag activity 2/846 15/18639 0.133333333333333 2.93758865248227 0.146441993178913 0.675938274071185 GO:0035401 histone H3Y41 kinase activity 8/846 115/18639 0.0695652173913043 1.53265494912118 0.151922726266134 0.69480256003365 GO:0140801 histone H2AXY142 kinase activity 8/846 115/18639 0.0695652173913043 1.53265494912118 0.151922726266134 0.69480256003365 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/846 30/18639 0.1 2.2031914893617 0.153563504942083 0.699099609256879 GO:0004518 nuclease activity 13/846 209/18639 0.062200956937799 1.37040618955513 0.156238404497306 0.708044042199154 GO:0003688 DNA replication origin binding 2/846 16/18639 0.125 2.75398936170213 0.162571467293304 0.723588182551001 GO:0022841 potassium ion leak channel activity 2/846 16/18639 0.125 2.75398936170213 0.162571467293304 0.723588182551001 GO:0030275 LRR domain binding 2/846 16/18639 0.125 2.75398936170213 0.162571467293304 0.723588182551001 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/846 16/18639 0.125 2.75398936170213 0.162571467293304 0.723588182551001 GO:0002020 protease binding 9/846 136/18639 0.0661764705882353 1.45799436795995 0.165683089766441 0.725580358858861 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 20/846 349/18639 0.0573065902578797 1.26257391940499 0.169703357307344 0.725580358858861 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 4/846 48/18639 0.0833333333333333 1.83599290780142 0.172442191296593 0.725580358858861 GO:0004721 phosphoprotein phosphatase activity 11/846 175/18639 0.0628571428571429 1.3848632218845 0.172797158502759 0.725580358858861 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/846 17/18639 0.117647058823529 2.59198998748436 0.178996514186845 0.725580358858861 GO:0008429 phosphatidylethanolamine binding 2/846 17/18639 0.117647058823529 2.59198998748436 0.178996514186845 0.725580358858861 GO:0019198 transmembrane receptor protein phosphatase activity 2/846 17/18639 0.117647058823529 2.59198998748436 0.178996514186845 0.725580358858861 GO:0036041 long-chain fatty acid binding 2/846 17/18639 0.117647058823529 2.59198998748436 0.178996514186845 0.725580358858861 GO:0051787 misfolded protein binding 2/846 17/18639 0.117647058823529 2.59198998748436 0.178996514186845 0.725580358858861 GO:0070402 NADPH binding 2/846 17/18639 0.117647058823529 2.59198998748436 0.178996514186845 0.725580358858861 GO:0070403 NAD+ binding 2/846 17/18639 0.117647058823529 2.59198998748436 0.178996514186845 0.725580358858861 GO:0070492 oligosaccharide binding 2/846 17/18639 0.117647058823529 2.59198998748436 0.178996514186845 0.725580358858861 GO:0005004 GPI-linked ephrin receptor activity 4/846 49/18639 0.0816326530612245 1.79852366478506 0.181522251215853 0.725580358858861 GO:0005008 hepatocyte growth factor receptor activity 4/846 49/18639 0.0816326530612245 1.79852366478506 0.181522251215853 0.725580358858861 GO:0005009 insulin receptor activity 4/846 49/18639 0.0816326530612245 1.79852366478506 0.181522251215853 0.725580358858861 GO:0005011 macrophage colony-stimulating factor receptor activity 4/846 49/18639 0.0816326530612245 1.79852366478506 0.181522251215853 0.725580358858861 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/846 49/18639 0.0816326530612245 1.79852366478506 0.181522251215853 0.725580358858861 GO:0005020 stem cell factor receptor activity 4/846 49/18639 0.0816326530612245 1.79852366478506 0.181522251215853 0.725580358858861 GO:0008288 boss receptor activity 4/846 49/18639 0.0816326530612245 1.79852366478506 0.181522251215853 0.725580358858861 GO:0036332 placental growth factor receptor activity 4/846 49/18639 0.0816326530612245 1.79852366478506 0.181522251215853 0.725580358858861 GO:0038062 protein tyrosine kinase collagen receptor activity 4/846 49/18639 0.0816326530612245 1.79852366478506 0.181522251215853 0.725580358858861 GO:0060175 brain-derived neurotrophic factor receptor activity 4/846 49/18639 0.0816326530612245 1.79852366478506 0.181522251215853 0.725580358858861 GO:0051117 ATPase binding 6/846 84/18639 0.0714285714285714 1.57370820668693 0.18174035617407 0.725580358858861 GO:0071889 14-3-3 protein binding 3/846 33/18639 0.0909090909090909 2.00290135396518 0.187466383089484 0.725580358858861 GO:0140416 transcription regulator inhibitor activity 3/846 33/18639 0.0909090909090909 2.00290135396518 0.187466383089484 0.725580358858861 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5/846 67/18639 0.0746268656716418 1.644172753255 0.187500473210088 0.725580358858861 GO:0008017 microtubule binding 16/846 276/18639 0.0579710144927536 1.27721245760099 0.189916354993607 0.725580358858861 GO:0005006 epidermal growth factor receptor activity 4/846 50/18639 0.08 1.76255319148936 0.190756402663458 0.725580358858861 GO:0005007 fibroblast growth factor receptor activity 4/846 50/18639 0.08 1.76255319148936 0.190756402663458 0.725580358858861 GO:0005017 platelet-derived growth factor receptor activity 4/846 50/18639 0.08 1.76255319148936 0.190756402663458 0.725580358858861 GO:0005019 platelet-derived growth factor beta-receptor activity 4/846 50/18639 0.08 1.76255319148936 0.190756402663458 0.725580358858861 GO:0022804 active transmembrane transporter activity 25/846 457/18639 0.0547045951859956 1.20524698542763 0.19365042642942 0.725580358858861 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/846 86/18639 0.0697674418604651 1.53711034141514 0.195607096642666 0.725580358858861 GO:0050660 flavin adenine dinucleotide binding 6/846 86/18639 0.0697674418604651 1.53711034141514 0.195607096642666 0.725580358858861 GO:0000400 four-way junction DNA binding 2/846 18/18639 0.111111111111111 2.44799054373522 0.195657171683514 0.725580358858861 GO:0000900 mRNA regulatory element binding translation repressor activity 2/846 18/18639 0.111111111111111 2.44799054373522 0.195657171683514 0.725580358858861 GO:0008525 phosphatidylcholine transporter activity 2/846 18/18639 0.111111111111111 2.44799054373522 0.195657171683514 0.725580358858861 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/846 18/18639 0.111111111111111 2.44799054373522 0.195657171683514 0.725580358858861 GO:0030228 lipoprotein particle receptor activity 2/846 18/18639 0.111111111111111 2.44799054373522 0.195657171683514 0.725580358858861 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/846 18/18639 0.111111111111111 2.44799054373522 0.195657171683514 0.725580358858861 GO:0050811 GABA receptor binding 2/846 18/18639 0.111111111111111 2.44799054373522 0.195657171683514 0.725580358858861 GO:0070628 proteasome binding 2/846 18/18639 0.111111111111111 2.44799054373522 0.195657171683514 0.725580358858861 GO:0098641 cadherin binding involved in cell-cell adhesion 2/846 18/18639 0.111111111111111 2.44799054373522 0.195657171683514 0.725580358858861 GO:1901611 phosphatidylglycerol binding 2/846 18/18639 0.111111111111111 2.44799054373522 0.195657171683514 0.725580358858861 GO:0016853 isomerase activity 11/846 180/18639 0.0611111111111111 1.34639479905437 0.195936846853535 0.725580358858861 GO:0004866 endopeptidase inhibitor activity 10/846 161/18639 0.062111801242236 1.3684419188582 0.196801123490254 0.725580358858861 GO:0015035 protein-disulfide reductase activity 3/846 34/18639 0.0882352941176471 1.94399249061327 0.199168982093325 0.725580358858861 GO:0005010 insulin-like growth factor receptor activity 4/846 51/18639 0.0784313725490196 1.72799332498957 0.200135003697279 0.725580358858861 GO:0005021 vascular endothelial growth factor receptor activity 4/846 51/18639 0.0784313725490196 1.72799332498957 0.200135003697279 0.725580358858861 GO:0005030 neurotrophin receptor activity 4/846 51/18639 0.0784313725490196 1.72799332498957 0.200135003697279 0.725580358858861 GO:0005048 signal sequence binding 4/846 51/18639 0.0784313725490196 1.72799332498957 0.200135003697279 0.725580358858861 GO:0005080 protein kinase C binding 4/846 52/18639 0.0769230769230769 1.69476268412439 0.209648383018229 0.738190959559869 GO:0004197 cysteine-type endopeptidase activity 6/846 88/18639 0.0681818181818182 1.50217601547389 0.209855257899974 0.738190959559869 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/846 19/18639 0.105263157894737 2.31914893617021 0.212498300294566 0.738190959559869 GO:0016918 retinal binding 2/846 19/18639 0.105263157894737 2.31914893617021 0.212498300294566 0.738190959559869 GO:0022840 leak channel activity 2/846 19/18639 0.105263157894737 2.31914893617021 0.212498300294566 0.738190959559869 GO:0022842 narrow pore channel activity 2/846 19/18639 0.105263157894737 2.31914893617021 0.212498300294566 0.738190959559869 GO:0034987 immunoglobulin receptor binding 2/846 19/18639 0.105263157894737 2.31914893617021 0.212498300294566 0.738190959559869 GO:0043395 heparan sulfate proteoglycan binding 2/846 19/18639 0.105263157894737 2.31914893617021 0.212498300294566 0.738190959559869 GO:0046527 glucosyltransferase activity 2/846 19/18639 0.105263157894737 2.31914893617021 0.212498300294566 0.738190959559869 GO:0046624 sphingolipid transporter activity 2/846 19/18639 0.105263157894737 2.31914893617021 0.212498300294566 0.738190959559869 GO:0097001 ceramide binding 2/846 19/18639 0.105263157894737 2.31914893617021 0.212498300294566 0.738190959559869 GO:1990380 K48-linked deubiquitinase activity 2/846 19/18639 0.105263157894737 2.31914893617021 0.212498300294566 0.738190959559869 GO:0008237 metallopeptidase activity 11/846 184/18639 0.0597826086956522 1.31712534690102 0.215385193593292 0.740469368239162 GO:0004864 protein phosphatase inhibitor activity 4/846 53/18639 0.0754716981132075 1.66278602970695 0.2192868681506 0.740469368239162 GO:0005003 ephrin receptor activity 4/846 53/18639 0.0754716981132075 1.66278602970695 0.2192868681506 0.740469368239162 GO:0005005 transmembrane-ephrin receptor activity 4/846 53/18639 0.0754716981132075 1.66278602970695 0.2192868681506 0.740469368239162 GO:0016251 RNA polymerase II general transcription initiation factor activity 4/846 53/18639 0.0754716981132075 1.66278602970695 0.2192868681506 0.740469368239162 GO:0016860 intramolecular oxidoreductase activity 4/846 53/18639 0.0754716981132075 1.66278602970695 0.2192868681506 0.740469368239162 GO:0038064 collagen receptor activity 4/846 53/18639 0.0754716981132075 1.66278602970695 0.2192868681506 0.740469368239162 GO:0019783 ubiquitin-like protein peptidase activity 8/846 127/18639 0.062992125984252 1.38783715865304 0.219838448343823 0.740469368239162 GO:0042826 histone deacetylase binding 8/846 127/18639 0.062992125984252 1.38783715865304 0.219838448343823 0.740469368239162 GO:0004033 aldo-keto reductase (NADPH) activity 3/846 36/18639 0.0833333333333333 1.83599290780142 0.223059165495621 0.741299959997113 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/846 36/18639 0.0833333333333333 1.83599290780142 0.223059165495621 0.741299959997113 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/846 36/18639 0.0833333333333333 1.83599290780142 0.223059165495621 0.741299959997113 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/846 36/18639 0.0833333333333333 1.83599290780142 0.223059165495621 0.741299959997113 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 8/846 128/18639 0.0625 1.37699468085106 0.225956768814134 0.748434878763095 GO:0030695 GTPase regulator activity 26/846 489/18639 0.0531697341513292 1.17143105773833 0.228816824654353 0.752568624990313 GO:0140463 chromatin-protein adaptor activity 4/846 54/18639 0.0740740740740741 1.63199369582348 0.229040811817883 0.752568624990313 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/846 20/18639 0.1 2.2031914893617 0.229469269806474 0.752568624990313 GO:0008234 cysteine-type peptidase activity 11/846 187/18639 0.0588235294117647 1.29599499374218 0.23047397047234 0.753385405117779 GO:0060589 nucleoside-triphosphatase regulator activity 26/846 490/18639 0.0530612244897959 1.16904038211029 0.231936175999011 0.75568747539547 GO:0042805 actinin binding 3/846 37/18639 0.0810810810810811 1.78637147786084 0.235209051439214 0.763854802230933 GO:0030414 peptidase inhibitor activity 10/846 169/18639 0.0591715976331361 1.3036636031726 0.238988553847511 0.773609052551844 GO:0051015 actin filament binding 12/846 209/18639 0.0574162679425837 1.26499032882012 0.241793123042117 0.778324085210689 GO:0019842 vitamin binding 9/846 150/18639 0.06 1.32191489361702 0.242075381363739 0.778324085210689 GO:0031491 nucleosome binding 5/846 74/18639 0.0675675675675676 1.48864289821737 0.245111472903384 0.778324085210689 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/846 21/18639 0.0952380952380952 2.09827760891591 0.246523664331262 0.778324085210689 GO:0070182 DNA polymerase binding 2/846 21/18639 0.0952380952380952 2.09827760891591 0.246523664331262 0.778324085210689 GO:0005085 guanyl-nucleotide exchange factor activity 13/846 230/18639 0.0565217391304348 1.24528214616096 0.247003359348009 0.778324085210689 GO:0000146 microfilament motor activity 3/846 38/18639 0.0789473684210526 1.73936170212766 0.24747114845716 0.778324085210689 GO:0005501 retinoid binding 3/846 38/18639 0.0789473684210526 1.73936170212766 0.24747114845716 0.778324085210689 GO:0019840 isoprenoid binding 3/846 38/18639 0.0789473684210526 1.73936170212766 0.24747114845716 0.778324085210689 GO:0019212 phosphatase inhibitor activity 4/846 56/18639 0.0714285714285714 1.57370820668693 0.248856757531171 0.780220714649616 GO:0044183 protein folding chaperone 5/846 75/18639 0.0666666666666667 1.46879432624113 0.253703830014386 0.792923882521451 GO:0141003 histone H2AX kinase activity 19/846 354/18639 0.0536723163841808 1.18250390671956 0.257857563519774 0.801305328590276 GO:0000217 DNA secondary structure binding 3/846 39/18639 0.0769230769230769 1.69476268412439 0.259827879750128 0.801305328590276 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/846 39/18639 0.0769230769230769 1.69476268412439 0.259827879750128 0.801305328590276 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/846 39/18639 0.0769230769230769 1.69476268412439 0.259827879750128 0.801305328590276 GO:0098631 cell adhesion mediator activity 5/846 76/18639 0.0657894736842105 1.44946808510638 0.262369076304246 0.801305328590276 GO:0031683 G-protein beta/gamma-subunit complex binding 2/846 22/18639 0.0909090909090909 2.00290135396518 0.263619004791987 0.801305328590276 GO:0034062 5'-3' RNA polymerase activity 2/846 22/18639 0.0909090909090909 2.00290135396518 0.263619004791987 0.801305328590276 GO:0070034 telomerase RNA binding 2/846 22/18639 0.0909090909090909 2.00290135396518 0.263619004791987 0.801305328590276 GO:0097747 RNA polymerase activity 2/846 22/18639 0.0909090909090909 2.00290135396518 0.263619004791987 0.801305328590276 GO:0005506 iron ion binding 9/846 154/18639 0.0584415584415584 1.28757944183476 0.265893110442076 0.805385019609915 GO:0001221 transcription coregulator binding 7/846 115/18639 0.0608695652173913 1.34107308048104 0.267384595276712 0.805385019609915 GO:0101005 deubiquitinase activity 7/846 115/18639 0.0608695652173913 1.34107308048104 0.267384595276712 0.805385019609915 GO:0005126 cytokine receptor binding 15/846 275/18639 0.0545454545454545 1.20174081237911 0.268586461265169 0.806568379160765 GO:0140996 histone H3 kinase activity 19/846 357/18639 0.0532212885154062 1.17256689910007 0.269627834772749 0.807264117923216 GO:0015036 disulfide oxidoreductase activity 3/846 40/18639 0.075 1.65239361702128 0.272262231138097 0.810284908790098 GO:0071949 FAD binding 3/846 40/18639 0.075 1.65239361702128 0.272262231138097 0.810284908790098 GO:0140789 histone phosphatase activity 8/846 136/18639 0.0588235294117647 1.29599499374218 0.276908848868344 0.821661078338507 GO:0003887 DNA-directed DNA polymerase activity 2/846 23/18639 0.0869565217391304 1.91581868640148 0.280716487871164 0.822908692979092 GO:0005212 structural constituent of eye lens 2/846 23/18639 0.0869565217391304 1.91581868640148 0.280716487871164 0.822908692979092 GO:0008171 O-methyltransferase activity 2/846 23/18639 0.0869565217391304 1.91581868640148 0.280716487871164 0.822908692979092 GO:0140103 catalytic activity, acting on a glycoprotein 2/846 23/18639 0.0869565217391304 1.91581868640148 0.280716487871164 0.822908692979092 GO:0035173 histone kinase activity 19/846 360/18639 0.0527777777777778 1.16279550827423 0.281591947540154 0.822908692979092 GO:0001530 lipopolysaccharide binding 3/846 41/18639 0.0731707317073171 1.61209133367929 0.284757772394972 0.822908692979092 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/846 41/18639 0.0731707317073171 1.61209133367929 0.284757772394972 0.822908692979092 GO:0042287 MHC protein binding 3/846 41/18639 0.0731707317073171 1.61209133367929 0.284757772394972 0.822908692979092 GO:0061650 ubiquitin-like protein conjugating enzyme activity 3/846 41/18639 0.0731707317073171 1.61209133367929 0.284757772394972 0.822908692979092 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/846 60/18639 0.0666666666666667 1.46879432624113 0.289457871700385 0.831463050294491 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 4/846 60/18639 0.0666666666666667 1.46879432624113 0.289457871700385 0.831463050294491 GO:0042578 phosphoric ester hydrolase activity 19/846 363/18639 0.0523415977961433 1.15318562804056 0.293736683425229 0.831463050294491 GO:0031492 nucleosomal DNA binding 3/846 42/18639 0.0714285714285714 1.57370820668693 0.297298673864454 0.831463050294491 GO:0005540 hyaluronic acid binding 2/846 24/18639 0.0833333333333333 1.83599290780142 0.297780740502118 0.831463050294491 GO:0015149 hexose transmembrane transporter activity 2/846 24/18639 0.0833333333333333 1.83599290780142 0.297780740502118 0.831463050294491 GO:0030215 semaphorin receptor binding 2/846 24/18639 0.0833333333333333 1.83599290780142 0.297780740502118 0.831463050294491 GO:0050431 transforming growth factor beta binding 2/846 24/18639 0.0833333333333333 1.83599290780142 0.297780740502118 0.831463050294491 GO:0050699 WW domain binding 2/846 24/18639 0.0833333333333333 1.83599290780142 0.297780740502118 0.831463050294491 GO:0055056 D-glucose transmembrane transporter activity 2/846 24/18639 0.0833333333333333 1.83599290780142 0.297780740502118 0.831463050294491 GO:0070300 phosphatidic acid binding 2/846 24/18639 0.0833333333333333 1.83599290780142 0.297780740502118 0.831463050294491 GO:0015026 coreceptor activity 4/846 61/18639 0.0655737704918033 1.44471573072899 0.299756757107085 0.831463050294491 GO:0043130 ubiquitin binding 6/846 100/18639 0.06 1.32191489361702 0.301592123448297 0.831463050294491 GO:0004713 protein tyrosine kinase activity 8/846 140/18639 0.0571428571428571 1.25896656534954 0.303482269434187 0.831463050294491 GO:0000030 mannosyltransferase activity 2/846 25/18639 0.08 1.76255319148936 0.314779589032667 0.831463050294491 GO:0001848 complement binding 2/846 25/18639 0.08 1.76255319148936 0.314779589032667 0.831463050294491 GO:0015271 outward rectifier potassium channel activity 2/846 25/18639 0.08 1.76255319148936 0.314779589032667 0.831463050294491 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/846 25/18639 0.08 1.76255319148936 0.314779589032667 0.831463050294491 GO:0001046 core promoter sequence-specific DNA binding 3/846 44/18639 0.0681818181818182 1.50217601547389 0.322456311947442 0.831463050294491 GO:0016790 thiolester hydrolase activity 3/846 44/18639 0.0681818181818182 1.50217601547389 0.322456311947442 0.831463050294491 GO:0004435 phosphatidylinositol phospholipase C activity 2/846 26/18639 0.0769230769230769 1.69476268412439 0.331683842237461 0.831463050294491 GO:0008157 protein phosphatase 1 binding 2/846 26/18639 0.0769230769230769 1.69476268412439 0.331683842237461 0.831463050294491 GO:0008198 ferrous iron binding 2/846 26/18639 0.0769230769230769 1.69476268412439 0.331683842237461 0.831463050294491 GO:0015145 monosaccharide transmembrane transporter activity 2/846 26/18639 0.0769230769230769 1.69476268412439 0.331683842237461 0.831463050294491 GO:0043548 phosphatidylinositol 3-kinase binding 2/846 26/18639 0.0769230769230769 1.69476268412439 0.331683842237461 0.831463050294491 GO:0070412 R-SMAD binding 2/846 26/18639 0.0769230769230769 1.69476268412439 0.331683842237461 0.831463050294491 GO:0120014 phospholipid transfer activity 2/846 26/18639 0.0769230769230769 1.69476268412439 0.331683842237461 0.831463050294491 GO:0042393 histone binding 13/846 247/18639 0.0526315789473684 1.15957446808511 0.331879932295495 0.831463050294491 GO:0008009 chemokine activity 3/846 45/18639 0.0666666666666667 1.46879432624113 0.335044484468911 0.831463050294491 GO:0004679 AMP-activated protein kinase activity 13/846 248/18639 0.0524193548387097 1.15489876458476 0.337082436490227 0.831463050294491 GO:0004180 carboxypeptidase activity 3/846 46/18639 0.0652173913043478 1.43686401480111 0.34762089605115 0.831463050294491 GO:0004364 glutathione transferase activity 2/846 27/18639 0.0740740740740741 1.63199369582348 0.348467087399649 0.831463050294491 GO:0005385 zinc ion transmembrane transporter activity 2/846 27/18639 0.0740740740740741 1.63199369582348 0.348467087399649 0.831463050294491 GO:0008320 protein transmembrane transporter activity 2/846 27/18639 0.0740740740740741 1.63199369582348 0.348467087399649 0.831463050294491 GO:0008395 steroid hydroxylase activity 2/846 27/18639 0.0740740740740741 1.63199369582348 0.348467087399649 0.831463050294491 GO:0015252 proton channel activity 2/846 27/18639 0.0740740740740741 1.63199369582348 0.348467087399649 0.831463050294491 GO:0016791 phosphatase activity 14/846 273/18639 0.0512820512820513 1.12984178941626 0.358231017886635 0.831463050294491 GO:0001784 phosphotyrosine residue binding 3/846 47/18639 0.0638297872340425 1.40629244001811 0.360172834044552 0.831463050294491 GO:0043495 protein-membrane adaptor activity 3/846 47/18639 0.0638297872340425 1.40629244001811 0.360172834044552 0.831463050294491 GO:0016500 protein-hormone receptor activity 4/846 67/18639 0.0597014925373134 1.315338202604 0.362136855850233 0.831463050294491 GO:0031490 chromatin DNA binding 7/846 128/18639 0.0546875 1.20487034574468 0.362291070196047 0.831463050294491 GO:0016866 intramolecular transferase activity 2/846 28/18639 0.0714285714285714 1.57370820668693 0.365105498724699 0.831463050294491 GO:0051119 sugar transmembrane transporter activity 2/846 28/18639 0.0714285714285714 1.57370820668693 0.365105498724699 0.831463050294491 GO:0051393 alpha-actinin binding 2/846 28/18639 0.0714285714285714 1.57370820668693 0.365105498724699 0.831463050294491 GO:0097718 disordered domain specific binding 2/846 28/18639 0.0714285714285714 1.57370820668693 0.365105498724699 0.831463050294491 GO:0004843 cysteine-type deubiquitinase activity 6/846 108/18639 0.0555555555555556 1.22399527186761 0.36633431828216 0.831463050294491 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0003796 lysozyme activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0004090 carbonyl reductase (NADPH) activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0004935 adrenergic receptor activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0004955 prostaglandin receptor activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0005031 tumor necrosis factor receptor activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0005131 growth hormone receptor binding 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0005528 FK506 binding 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0015187 glycine transmembrane transporter activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0016427 tRNA (cytidine) methyltransferase activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0033204 ribonuclease P RNA binding 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0035374 chondroitin sulfate binding 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0042166 acetylcholine binding 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0043208 glycosphingolipid binding 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0045322 unmethylated CpG binding 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0050308 sugar-phosphatase activity 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0098505 G-rich strand telomeric DNA binding 1/846 10/18639 0.1 2.2031914893617 0.371629434481621 0.831463050294491 GO:0005548 phospholipid transporter activity 4/846 68/18639 0.0588235294117647 1.29599499374218 0.37255678593386 0.831463050294491 GO:0140223 general transcription initiation factor activity 4/846 68/18639 0.0588235294117647 1.29599499374218 0.37255678593386 0.831463050294491 GO:0140693 molecular condensate scaffold activity 3/846 48/18639 0.0625 1.37699468085106 0.37268821022775 0.831463050294491 GO:0106310 protein serine kinase activity 18/846 361/18639 0.0498614958448753 1.09854423292273 0.374989031542916 0.831463050294491 GO:0016798 hydrolase activity, acting on glycosyl bonds 7/846 130/18639 0.0538461538461538 1.18633387888707 0.377236172810413 0.831463050294491 GO:0004181 metallocarboxypeptidase activity 2/846 29/18639 0.0689655172413793 1.51944240645635 0.38157765738901 0.831463050294491 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/846 29/18639 0.0689655172413793 1.51944240645635 0.38157765738901 0.831463050294491 GO:0043236 laminin binding 2/846 29/18639 0.0689655172413793 1.51944240645635 0.38157765738901 0.831463050294491 GO:0097472 cyclin-dependent protein kinase activity 2/846 29/18639 0.0689655172413793 1.51944240645635 0.38157765738901 0.831463050294491 GO:0004222 metalloendopeptidase activity 6/846 110/18639 0.0545454545454545 1.20174081237911 0.382678507573121 0.831463050294491 GO:0001222 transcription corepressor binding 3/846 49/18639 0.0612244897959184 1.3488927485888 0.385155555380699 0.831463050294491 GO:0035254 glutamate receptor binding 3/846 49/18639 0.0612244897959184 1.3488927485888 0.385155555380699 0.831463050294491 GO:0140030 modification-dependent protein binding 9/846 173/18639 0.0520231213872832 1.14616898290493 0.386198371567586 0.831463050294491 GO:0097110 scaffold protein binding 4/846 70/18639 0.0571428571428571 1.25896656534954 0.393349731201872 0.831463050294491 GO:0001965 G-protein alpha-subunit binding 2/846 30/18639 0.0666666666666667 1.46879432624113 0.39786438256379 0.831463050294491 GO:0016769 transferase activity, transferring nitrogenous groups 2/846 30/18639 0.0666666666666667 1.46879432624113 0.39786438256379 0.831463050294491 GO:0031624 ubiquitin conjugating enzyme binding 2/846 30/18639 0.0666666666666667 1.46879432624113 0.39786438256379 0.831463050294491 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/846 30/18639 0.0666666666666667 1.46879432624113 0.39786438256379 0.831463050294491 GO:0048019 receptor antagonist activity 2/846 30/18639 0.0666666666666667 1.46879432624113 0.39786438256379 0.831463050294491 GO:0005200 structural constituent of cytoskeleton 6/846 112/18639 0.0535714285714286 1.1802811550152 0.399026878939946 0.831463050294491 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0001851 complement component C3b binding 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0003953 NAD+ nucleosidase activity 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0004954 prostanoid receptor activity 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0005536 D-glucose binding 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0008526 phosphatidylinositol transfer activity 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0010854 adenylate cyclase regulator activity 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0015217 ADP transmembrane transporter activity 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0019203 carbohydrate phosphatase activity 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0019206 nucleoside kinase activity 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0032794 GTPase activating protein binding 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0043522 leucine zipper domain binding 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0048185 activin binding 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0048407 platelet-derived growth factor binding 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0140031 phosphorylation-dependent protein binding 1/846 11/18639 0.0909090909090909 2.00290135396518 0.400165668226242 0.831463050294491 GO:0004674 protein serine/threonine kinase activity 21/846 433/18639 0.0484988452655889 1.06852243133016 0.408978517210798 0.831463050294491 GO:0031267 small GTPase binding 14/846 283/18639 0.049469964664311 1.08991805127434 0.409325331773682 0.831463050294491 GO:0008327 methyl-CpG binding 2/846 31/18639 0.0645161290322581 1.42141386410432 0.413948572790432 0.831463050294491 GO:0017147 Wnt-protein binding 2/846 31/18639 0.0645161290322581 1.42141386410432 0.413948572790432 0.831463050294491 GO:0070273 phosphatidylinositol-4-phosphate binding 2/846 31/18639 0.0645161290322581 1.42141386410432 0.413948572790432 0.831463050294491 GO:0042379 chemokine receptor binding 4/846 72/18639 0.0555555555555556 1.22399527186761 0.414034961566152 0.831463050294491 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/846 52/18639 0.0576923076923077 1.27107201309329 0.422163831601123 0.831463050294491 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 12/846 243/18639 0.0493827160493827 1.08799579721566 0.424296200830526 0.831463050294491 GO:0004032 aldose reductase (NADPH) activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0004300 enoyl-CoA hydratase activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0004526 ribonuclease P activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0004875 complement receptor activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0005049 nuclear export signal receptor activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0005165 neurotrophin receptor binding 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0005436 sodium:phosphate symporter activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0005527 macrolide binding 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0008179 adenylate cyclase binding 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0010853 cyclase activator activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0015166 polyol transmembrane transporter activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0016801 hydrolase activity, acting on ether bonds 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0016803 ether hydrolase activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0034452 dynactin binding 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0035197 siRNA binding 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0035251 UDP-glucosyltransferase activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0042301 phosphate ion binding 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0043047 single-stranded telomeric DNA binding 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0070008 serine-type exopeptidase activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0070410 co-SMAD binding 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:1990459 transferrin receptor binding 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:1990817 poly(A) RNA polymerase activity 1/846 12/18639 0.0833333333333333 1.83599290780142 0.427407446446158 0.831463050294491 GO:0008378 galactosyltransferase activity 2/846 32/18639 0.0625 1.37699468085106 0.429815057117544 0.831463050294491 GO:0022884 macromolecule transmembrane transporter activity 2/846 32/18639 0.0625 1.37699468085106 0.429815057117544 0.831463050294491 GO:0051059 NF-kappaB binding 2/846 32/18639 0.0625 1.37699468085106 0.429815057117544 0.831463050294491 GO:0140142 nucleocytoplasmic carrier activity 2/846 32/18639 0.0625 1.37699468085106 0.429815057117544 0.831463050294491 GO:0019207 kinase regulator activity 14/846 287/18639 0.0487804878048781 1.0747275557862 0.429905430271457 0.831463050294491 GO:0017046 peptide hormone binding 3/846 53/18639 0.0566037735849057 1.24708952228021 0.434336449408154 0.831463050294491 GO:0140296 general transcription initiation factor binding 3/846 53/18639 0.0566037735849057 1.24708952228021 0.434336449408154 0.831463050294491 GO:0048029 monosaccharide binding 4/846 74/18639 0.0540540540540541 1.19091431857389 0.434561722031359 0.831463050294491 GO:0004676 3-phosphoinositide-dependent protein kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0004711 ribosomal protein S6 kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0035175 histone H3S10 kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0035979 histone H2AXS139 kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0044022 histone H3S28 kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0044023 histone H4S1 kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0044024 histone H2AS1 kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0044025 histone H2BS14 kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0072354 histone H3T3 kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0072371 histone H2AS121 kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0072518 Rho-dependent protein serine/threonine kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0140823 histone H2BS36 kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0140855 histone H3S57 kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0140995 histone H2A kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0140997 histone H4 kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:0140998 histone H2B kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:1990244 histone H2AT120 kinase activity 12/846 245/18639 0.0489795918367347 1.07911419887104 0.435458019216436 0.831463050294491 GO:1990782 protein tyrosine kinase binding 6/846 117/18639 0.0512820512820513 1.12984178941626 0.439735495727123 0.831463050294491 GO:0004677 DNA-dependent protein kinase activity 12/846 246/18639 0.0487804878048781 1.0747275557862 0.441035591234584 0.831463050294491 GO:0140857 histone H3T45 kinase activity 12/846 246/18639 0.0487804878048781 1.0747275557862 0.441035591234584 0.831463050294491 GO:0099106 ion channel regulator activity 8/846 160/18639 0.05 1.10159574468085 0.441319929205865 0.831463050294491 GO:0016407 acetyltransferase activity 5/846 96/18639 0.0520833333333333 1.14749556737589 0.44235825143339 0.831463050294491 GO:0003725 double-stranded RNA binding 4/846 75/18639 0.0533333333333333 1.17503546099291 0.4447508990464 0.831463050294491 GO:0030296 protein tyrosine kinase activator activity 2/846 33/18639 0.0606060606060606 1.33526756931012 0.445450455441935 0.831463050294491 GO:0140311 protein sequestering activity 2/846 33/18639 0.0606060606060606 1.33526756931012 0.445450455441935 0.831463050294491 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/846 54/18639 0.0555555555555556 1.22399527186761 0.446412663384052 0.831463050294491 GO:0035402 histone H3T11 kinase activity 12/846 247/18639 0.048582995951417 1.07037643207856 0.446609497222963 0.831463050294491 GO:0035403 histone H3T6 kinase activity 12/846 247/18639 0.048582995951417 1.07037643207856 0.446609497222963 0.831463050294491 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/846 13/18639 0.0769230769230769 1.69476268412439 0.453413421659909 0.831463050294491 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/846 13/18639 0.0769230769230769 1.69476268412439 0.453413421659909 0.831463050294491 GO:0005035 death receptor activity 1/846 13/18639 0.0769230769230769 1.69476268412439 0.453413421659909 0.831463050294491 GO:0005172 vascular endothelial growth factor receptor binding 1/846 13/18639 0.0769230769230769 1.69476268412439 0.453413421659909 0.831463050294491 GO:0019104 DNA N-glycosylase activity 1/846 13/18639 0.0769230769230769 1.69476268412439 0.453413421659909 0.831463050294491 GO:0019855 calcium channel inhibitor activity 1/846 13/18639 0.0769230769230769 1.69476268412439 0.453413421659909 0.831463050294491 GO:0039706 co-receptor binding 1/846 13/18639 0.0769230769230769 1.69476268412439 0.453413421659909 0.831463050294491 GO:0046974 histone H3K9 methyltransferase activity 1/846 13/18639 0.0769230769230769 1.69476268412439 0.453413421659909 0.831463050294491 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/846 13/18639 0.0769230769230769 1.69476268412439 0.453413421659909 0.831463050294491 GO:0061459 L-arginine transmembrane transporter activity 1/846 13/18639 0.0769230769230769 1.69476268412439 0.453413421659909 0.831463050294491 GO:0071837 HMG box domain binding 1/846 13/18639 0.0769230769230769 1.69476268412439 0.453413421659909 0.831463050294491 GO:1901338 catecholamine binding 1/846 13/18639 0.0769230769230769 1.69476268412439 0.453413421659909 0.831463050294491 GO:0017022 myosin binding 4/846 76/18639 0.0526315789473684 1.15957446808511 0.454883222532074 0.831463050294491 GO:0004725 protein tyrosine phosphatase activity 5/846 98/18639 0.0510204081632653 1.12407729049066 0.460200796830966 0.831463050294491 GO:0008376 acetylgalactosaminyltransferase activity 2/846 34/18639 0.0588235294117647 1.29599499374218 0.460843047526223 0.831463050294491 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 2/846 34/18639 0.0588235294117647 1.29599499374218 0.460843047526223 0.831463050294491 GO:0019825 oxygen binding 2/846 34/18639 0.0588235294117647 1.29599499374218 0.460843047526223 0.831463050294491 GO:0032182 ubiquitin-like protein binding 6/846 120/18639 0.05 1.10159574468085 0.463920478542506 0.831463050294491 GO:0005516 calmodulin binding 10/846 207/18639 0.0483091787439614 1.06434371466749 0.466000836385271 0.831463050294491 GO:0020037 heme binding 7/846 142/18639 0.0492957746478873 1.08608031165718 0.466701968158133 0.831463050294491 GO:0051082 unfolded protein binding 6/846 121/18639 0.0495867768595041 1.09249164761737 0.471924054908 0.831463050294491 GO:0019199 transmembrane receptor protein kinase activity 4/846 78/18639 0.0512820512820513 1.12984178941626 0.47495663630221 0.831463050294491 GO:0005154 epidermal growth factor receptor binding 2/846 35/18639 0.0571428571428571 1.25896656534954 0.475982650194629 0.831463050294491 GO:0034061 DNA polymerase activity 2/846 35/18639 0.0571428571428571 1.25896656534954 0.475982650194629 0.831463050294491 GO:0061631 ubiquitin conjugating enzyme activity 2/846 35/18639 0.0571428571428571 1.25896656534954 0.475982650194629 0.831463050294491 GO:0140566 histone reader activity 2/846 35/18639 0.0571428571428571 1.25896656534954 0.475982650194629 0.831463050294491 GO:0004705 JUN kinase activity 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:0005161 platelet-derived growth factor receptor binding 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:0005347 ATP transmembrane transporter activity 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:0008195 phosphatidate phosphatase activity 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:0015926 glucosidase activity 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:0030983 mismatched DNA binding 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:0031404 chloride ion binding 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:0032454 histone H3K9 demethylase activity 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:0042813 Wnt receptor activity 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:0061783 peptidoglycan muralytic activity 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:0070742 C2H2 zinc finger domain binding 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:0098847 sequence-specific single stranded DNA binding 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:1901612 cardiolipin binding 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:1990825 sequence-specific mRNA binding 1/846 14/18639 0.0714285714285714 1.57370820668693 0.478239591813229 0.831463050294491 GO:0015631 tubulin binding 18/846 385/18639 0.0467532467532468 1.03006355346781 0.483066968176195 0.831463050294491 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/846 36/18639 0.0555555555555556 1.22399527186761 0.490860502235747 0.831463050294491 GO:0005484 SNAP receptor activity 2/846 36/18639 0.0555555555555556 1.22399527186761 0.490860502235747 0.831463050294491 GO:0016409 palmitoyltransferase activity 2/846 36/18639 0.0555555555555556 1.22399527186761 0.490860502235747 0.831463050294491 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/846 36/18639 0.0555555555555556 1.22399527186761 0.490860502235747 0.831463050294491 GO:0140098 catalytic activity, acting on RNA 18/846 387/18639 0.0465116279069767 1.02474022761009 0.492034608218273 0.831463050294491 GO:0000049 tRNA binding 4/846 80/18639 0.05 1.10159574468085 0.494743060183171 0.831463050294491 GO:0008238 exopeptidase activity 5/846 102/18639 0.0490196078431373 1.07999582811848 0.495352027341455 0.831463050294491 GO:0016247 channel regulator activity 8/846 168/18639 0.0476190476190476 1.04913880445795 0.496130455044322 0.831463050294491 GO:0000774 adenyl-nucleotide exchange factor activity 1/846 15/18639 0.0666666666666667 1.46879432624113 0.501939420287108 0.831463050294491 GO:0004559 alpha-mannosidase activity 1/846 15/18639 0.0666666666666667 1.46879432624113 0.501939420287108 0.831463050294491 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/846 15/18639 0.0666666666666667 1.46879432624113 0.501939420287108 0.831463050294491 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/846 15/18639 0.0666666666666667 1.46879432624113 0.501939420287108 0.831463050294491 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/846 15/18639 0.0666666666666667 1.46879432624113 0.501939420287108 0.831463050294491 GO:0004953 icosanoid receptor activity 1/846 15/18639 0.0666666666666667 1.46879432624113 0.501939420287108 0.831463050294491 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/846 15/18639 0.0666666666666667 1.46879432624113 0.501939420287108 0.831463050294491 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/846 15/18639 0.0666666666666667 1.46879432624113 0.501939420287108 0.831463050294491 GO:0015929 hexosaminidase activity 1/846 15/18639 0.0666666666666667 1.46879432624113 0.501939420287108 0.831463050294491 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/846 15/18639 0.0666666666666667 1.46879432624113 0.501939420287108 0.831463050294491 GO:0048531 beta-1,3-galactosyltransferase activity 1/846 15/18639 0.0666666666666667 1.46879432624113 0.501939420287108 0.831463050294491 GO:0140161 monocarboxylate:sodium symporter activity 1/846 15/18639 0.0666666666666667 1.46879432624113 0.501939420287108 0.831463050294491 GO:0004722 protein serine/threonine phosphatase activity 5/846 103/18639 0.0485436893203883 1.06951043172898 0.50400853183369 0.831463050294491 GO:0015101 organic cation transmembrane transporter activity 4/846 81/18639 0.0493827160493827 1.08799579721566 0.504517549376642 0.831463050294491 GO:0033192 calmodulin-dependent protein phosphatase activity 4/846 81/18639 0.0493827160493827 1.08799579721566 0.504517549376642 0.831463050294491 GO:0140791 histone H2AXS140 phosphatase activity 4/846 81/18639 0.0493827160493827 1.08799579721566 0.504517549376642 0.831463050294491 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 4/846 81/18639 0.0493827160493827 1.08799579721566 0.504517549376642 0.831463050294491 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 4/846 81/18639 0.0493827160493827 1.08799579721566 0.504517549376642 0.831463050294491 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 4/846 81/18639 0.0493827160493827 1.08799579721566 0.504517549376642 0.831463050294491 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 4/846 81/18639 0.0493827160493827 1.08799579721566 0.504517549376642 0.831463050294491 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 4/846 81/18639 0.0493827160493827 1.08799579721566 0.504517549376642 0.831463050294491 GO:1990439 MAP kinase serine/threonine phosphatase activity 4/846 81/18639 0.0493827160493827 1.08799579721566 0.504517549376642 0.831463050294491 GO:0004879 nuclear receptor activity 3/846 59/18639 0.0508474576271186 1.12026685899748 0.505087577954848 0.831463050294491 GO:0015459 potassium channel regulator activity 3/846 59/18639 0.0508474576271186 1.12026685899748 0.505087577954848 0.831463050294491 GO:0045309 protein phosphorylated amino acid binding 3/846 59/18639 0.0508474576271186 1.12026685899748 0.505087577954848 0.831463050294491 GO:0070888 E-box binding 3/846 59/18639 0.0508474576271186 1.12026685899748 0.505087577954848 0.831463050294491 GO:0141108 transporter regulator activity 8/846 170/18639 0.0470588235294118 1.03679599499374 0.509606330135763 0.831463050294491 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 4/846 82/18639 0.0487804878048781 1.0747275557862 0.514207442528447 0.831463050294491 GO:0033549 MAP kinase phosphatase activity 4/846 82/18639 0.0487804878048781 1.0747275557862 0.514207442528447 0.831463050294491 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 3/846 60/18639 0.05 1.10159574468085 0.516436509862978 0.831463050294491 GO:0098531 ligand-modulated transcription factor activity 3/846 60/18639 0.05 1.10159574468085 0.516436509862978 0.831463050294491 GO:0005109 frizzled binding 2/846 38/18639 0.0526315789473684 1.15957446808511 0.519802379239745 0.831463050294491 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 4/846 83/18639 0.0481927710843374 1.06177903101769 0.523808943677562 0.831463050294491 GO:0000062 fatty-acyl-CoA binding 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0004707 MAP kinase activity 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0004708 MAP kinase kinase activity 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0005159 insulin-like growth factor receptor binding 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0005521 lamin binding 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0015378 sodium:chloride symporter activity 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0015562 efflux transmembrane transporter activity 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0015923 mannosidase activity 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0016722 oxidoreductase activity, acting on metal ions 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0019841 retinol binding 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0022858 alanine transmembrane transporter activity 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0034450 ubiquitin-ubiquitin ligase activity 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0140328 floppase activity 1/846 16/18639 0.0625 1.37699468085106 0.524563950486695 0.831463050294491 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/846 61/18639 0.0491803278688525 1.08353679804674 0.527644083281387 0.835017700050067 GO:0000149 SNARE binding 5/846 106/18639 0.0471698113207547 1.03924126856684 0.529613226089453 0.836805683694429 GO:0004860 protein kinase inhibitor activity 4/846 84/18639 0.0476190476190476 1.04913880445795 0.533318483908822 0.839969582997465 GO:0017018 myosin phosphatase activity 4/846 84/18639 0.0476190476190476 1.04913880445795 0.533318483908822 0.839969582997465 GO:0015179 L-amino acid transmembrane transporter activity 3/846 62/18639 0.0483870967741935 1.06606039807824 0.538705777529827 0.839969582997465 GO:0046906 tetrapyrrole binding 7/846 152/18639 0.0460526315789474 1.01462765957447 0.538849039370433 0.839969582997465 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 6/846 130/18639 0.0461538461538462 1.01685761047463 0.542134938934912 0.839969582997465 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/846 17/18639 0.0588235294117647 1.29599499374218 0.546161915255436 0.839969582997465 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/846 17/18639 0.0588235294117647 1.29599499374218 0.546161915255436 0.839969582997465 GO:0004549 tRNA-specific ribonuclease activity 1/846 17/18639 0.0588235294117647 1.29599499374218 0.546161915255436 0.839969582997465 GO:0004550 nucleoside diphosphate kinase activity 1/846 17/18639 0.0588235294117647 1.29599499374218 0.546161915255436 0.839969582997465 GO:0004659 prenyltransferase activity 1/846 17/18639 0.0588235294117647 1.29599499374218 0.546161915255436 0.839969582997465 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/846 17/18639 0.0588235294117647 1.29599499374218 0.546161915255436 0.839969582997465 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/846 17/18639 0.0588235294117647 1.29599499374218 0.546161915255436 0.839969582997465 GO:0032977 membrane insertase activity 1/846 17/18639 0.0588235294117647 1.29599499374218 0.546161915255436 0.839969582997465 GO:0045236 CXCR chemokine receptor binding 1/846 17/18639 0.0588235294117647 1.29599499374218 0.546161915255436 0.839969582997465 GO:1901567 fatty acid derivative binding 1/846 17/18639 0.0588235294117647 1.29599499374218 0.546161915255436 0.839969582997465 GO:0004177 aminopeptidase activity 2/846 40/18639 0.05 1.10159574468085 0.547623098243082 0.839969582997465 GO:0015144 carbohydrate transmembrane transporter activity 2/846 40/18639 0.05 1.10159574468085 0.547623098243082 0.839969582997465 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/846 40/18639 0.05 1.10159574468085 0.547623098243082 0.839969582997465 GO:0030331 nuclear estrogen receptor binding 2/846 40/18639 0.05 1.10159574468085 0.547623098243082 0.839969582997465 GO:0005507 copper ion binding 3/846 63/18639 0.0476190476190476 1.04913880445795 0.549617497505885 0.841733709697953 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/846 41/18639 0.0487804878048781 1.0747275557862 0.561103371363498 0.851023346120267 GO:0017080 sodium channel regulator activity 2/846 41/18639 0.0487804878048781 1.0747275557862 0.561103371363498 0.851023346120267 GO:0140318 protein transporter activity 2/846 41/18639 0.0487804878048781 1.0747275557862 0.561103371363498 0.851023346120267 GO:0008081 phosphoric diester hydrolase activity 4/846 87/18639 0.0459770114942529 1.01296160430423 0.561262964423247 0.851023346120267 GO:0003746 translation elongation factor activity 1/846 18/18639 0.0555555555555556 1.22399527186761 0.566779841347901 0.851023346120267 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/846 18/18639 0.0555555555555556 1.22399527186761 0.566779841347901 0.851023346120267 GO:0015280 ligand-gated sodium channel activity 1/846 18/18639 0.0555555555555556 1.22399527186761 0.566779841347901 0.851023346120267 GO:0015373 monoatomic anion:sodium symporter activity 1/846 18/18639 0.0555555555555556 1.22399527186761 0.566779841347901 0.851023346120267 GO:0017075 syntaxin-1 binding 1/846 18/18639 0.0555555555555556 1.22399527186761 0.566779841347901 0.851023346120267 GO:0031690 adrenergic receptor binding 1/846 18/18639 0.0555555555555556 1.22399527186761 0.566779841347901 0.851023346120267 GO:0034185 apolipoprotein binding 1/846 18/18639 0.0555555555555556 1.22399527186761 0.566779841347901 0.851023346120267 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/846 18/18639 0.0555555555555556 1.22399527186761 0.566779841347901 0.851023346120267 GO:1990381 ubiquitin-specific protease binding 1/846 18/18639 0.0555555555555556 1.22399527186761 0.566779841347901 0.851023346120267 GO:0019894 kinesin binding 2/846 42/18639 0.0476190476190476 1.04913880445795 0.57429360623845 0.852481620639214 GO:0048487 beta-tubulin binding 2/846 42/18639 0.0476190476190476 1.04913880445795 0.57429360623845 0.852481620639214 GO:0005096 GTPase activator activity 12/846 271/18639 0.044280442804428 0.975582947318835 0.5767053655175 0.852481620639214 GO:0003727 single-stranded RNA binding 4/846 89/18639 0.0449438202247191 0.990198422185035 0.579377195547383 0.852481620639214 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/846 89/18639 0.0449438202247191 0.990198422185035 0.579377195547383 0.852481620639214 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/846 89/18639 0.0449438202247191 0.990198422185035 0.579377195547383 0.852481620639214 GO:0140104 molecular carrier activity 11/846 249/18639 0.0441767068273092 0.973297445099547 0.580119238979017 0.852481620639214 GO:0008235 metalloexopeptidase activity 3/846 66/18639 0.0454545454545455 1.00145067698259 0.581417892957208 0.852481620639214 GO:0003756 protein disulfide isomerase activity 1/846 19/18639 0.0526315789473684 1.15957446808511 0.586462149184198 0.852481620639214 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/846 19/18639 0.0526315789473684 1.15957446808511 0.586462149184198 0.852481620639214 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/846 19/18639 0.0526315789473684 1.15957446808511 0.586462149184198 0.852481620639214 GO:0008301 DNA binding, bending 1/846 19/18639 0.0526315789473684 1.15957446808511 0.586462149184198 0.852481620639214 GO:0008574 plus-end-directed microtubule motor activity 1/846 19/18639 0.0526315789473684 1.15957446808511 0.586462149184198 0.852481620639214 GO:0015245 fatty acid transmembrane transporter activity 1/846 19/18639 0.0526315789473684 1.15957446808511 0.586462149184198 0.852481620639214 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/846 19/18639 0.0526315789473684 1.15957446808511 0.586462149184198 0.852481620639214 GO:0030506 ankyrin binding 1/846 19/18639 0.0526315789473684 1.15957446808511 0.586462149184198 0.852481620639214 GO:0042577 lipid phosphatase activity 1/846 19/18639 0.0526315789473684 1.15957446808511 0.586462149184198 0.852481620639214 GO:0042800 histone H3K4 methyltransferase activity 1/846 19/18639 0.0526315789473684 1.15957446808511 0.586462149184198 0.852481620639214 GO:0042834 peptidoglycan binding 1/846 19/18639 0.0526315789473684 1.15957446808511 0.586462149184198 0.852481620639214 GO:0120227 acyl-CoA binding 1/846 19/18639 0.0526315789473684 1.15957446808511 0.586462149184198 0.852481620639214 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/846 43/18639 0.0465116279069767 1.02474022761009 0.587192332454284 0.852481620639214 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/846 43/18639 0.0465116279069767 1.02474022761009 0.587192332454284 0.852481620639214 GO:0019210 kinase inhibitor activity 4/846 90/18639 0.0444444444444444 0.97919621749409 0.588272171514322 0.852481620639214 GO:0140793 histone H2AXY142 phosphatase activity 4/846 90/18639 0.0444444444444444 0.97919621749409 0.588272171514322 0.852481620639214 GO:0042054 histone methyltransferase activity 3/846 67/18639 0.0447761194029851 0.986503651953001 0.591696691571598 0.856199711896783 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 10/846 229/18639 0.0436681222707424 0.962092353433058 0.595200530941918 0.860021636737814 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/846 91/18639 0.043956043956044 0.968435819499649 0.597056175454301 0.861454423918869 GO:1990841 promoter-specific chromatin binding 3/846 68/18639 0.0441176470588235 0.971996245306633 0.60181084106257 0.863283969033646 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/846 20/18639 0.05 1.10159574468085 0.605251248098815 0.863283969033646 GO:0010851 cyclase regulator activity 1/846 20/18639 0.05 1.10159574468085 0.605251248098815 0.863283969033646 GO:0015095 magnesium ion transmembrane transporter activity 1/846 20/18639 0.05 1.10159574468085 0.605251248098815 0.863283969033646 GO:0015464 acetylcholine receptor activity 1/846 20/18639 0.05 1.10159574468085 0.605251248098815 0.863283969033646 GO:0030742 GTP-dependent protein binding 1/846 20/18639 0.05 1.10159574468085 0.605251248098815 0.863283969033646 GO:0061608 nuclear import signal receptor activity 1/846 20/18639 0.05 1.10159574468085 0.605251248098815 0.863283969033646 GO:0140664 ATP-dependent DNA damage sensor activity 1/846 20/18639 0.05 1.10159574468085 0.605251248098815 0.863283969033646 GO:0046982 protein heterodimerization activity 16/846 369/18639 0.043360433604336 0.955313382921063 0.610849527389967 0.86666145546536 GO:0019887 protein kinase regulator activity 11/846 255/18639 0.0431372549019608 0.950396328744264 0.611910852263187 0.86666145546536 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/846 45/18639 0.0444444444444444 0.97919621749409 0.612112964279526 0.86666145546536 GO:0046915 transition metal ion transmembrane transporter activity 2/846 45/18639 0.0444444444444444 0.97919621749409 0.612112964279526 0.86666145546536 GO:0051539 4 iron, 4 sulfur cluster binding 2/846 45/18639 0.0444444444444444 0.97919621749409 0.612112964279526 0.86666145546536 GO:0051213 dioxygenase activity 4/846 93/18639 0.043010752688172 0.947609242736216 0.614283755071721 0.86666145546536 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/846 70/18639 0.0428571428571429 0.944224924012158 0.621537947138845 0.86666145546536 GO:0016410 N-acyltransferase activity 4/846 94/18639 0.0425531914893617 0.937528293345405 0.622724023894773 0.86666145546536 GO:0001846 opsonin binding 1/846 21/18639 0.0476190476190476 1.04913880445795 0.623187627287192 0.86666145546536 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/846 21/18639 0.0476190476190476 1.04913880445795 0.623187627287192 0.86666145546536 GO:0008373 sialyltransferase activity 1/846 21/18639 0.0476190476190476 1.04913880445795 0.623187627287192 0.86666145546536 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/846 21/18639 0.0476190476190476 1.04913880445795 0.623187627287192 0.86666145546536 GO:0015174 basic amino acid transmembrane transporter activity 1/846 21/18639 0.0476190476190476 1.04913880445795 0.623187627287192 0.86666145546536 GO:0019200 carbohydrate kinase activity 1/846 21/18639 0.0476190476190476 1.04913880445795 0.623187627287192 0.86666145546536 GO:0035613 RNA stem-loop binding 1/846 21/18639 0.0476190476190476 1.04913880445795 0.623187627287192 0.86666145546536 GO:0051010 microtubule plus-end binding 1/846 21/18639 0.0476190476190476 1.04913880445795 0.623187627287192 0.86666145546536 GO:0061891 calcium ion sensor activity 1/846 21/18639 0.0476190476190476 1.04913880445795 0.623187627287192 0.86666145546536 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/846 46/18639 0.0434782608695652 0.95790934320074 0.62413533101718 0.86666145546536 GO:0030291 protein serine/threonine kinase inhibitor activity 2/846 46/18639 0.0434782608695652 0.95790934320074 0.62413533101718 0.86666145546536 GO:0004867 serine-type endopeptidase inhibitor activity 4/846 95/18639 0.0421052631578947 0.927659574468085 0.631046695758343 0.873964722610559 GO:0140299 molecular sensor activity 3/846 71/18639 0.0422535211267606 0.930925981420437 0.631148044412841 0.873964722610559 GO:0140359 ABC-type transporter activity 2/846 47/18639 0.0425531914893617 0.937528293345405 0.635866997549297 0.878060106034139 GO:0140938 histone H3 methyltransferase activity 2/846 47/18639 0.0425531914893617 0.937528293345405 0.635866997549297 0.878060106034139 GO:0016874 ligase activity 7/846 167/18639 0.0419161676646707 0.923493438654606 0.638582245140642 0.879323709113188 GO:0008649 rRNA methyltransferase activity 1/846 22/18639 0.0454545454545455 1.00145067698259 0.640309942644107 0.879323709113188 GO:0015377 chloride:monoatomic cation symporter activity 1/846 22/18639 0.0454545454545455 1.00145067698259 0.640309942644107 0.879323709113188 GO:0140784 metal ion sensor activity 1/846 22/18639 0.0454545454545455 1.00145067698259 0.640309942644107 0.879323709113188 GO:0000295 adenine nucleotide transmembrane transporter activity 1/846 23/18639 0.0434782608695652 0.95790934320074 0.656655099679241 0.885906812422467 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/846 23/18639 0.0434782608695652 0.95790934320074 0.656655099679241 0.885906812422467 GO:0005158 insulin receptor binding 1/846 23/18639 0.0434782608695652 0.95790934320074 0.656655099679241 0.885906812422467 GO:0005283 amino acid:sodium symporter activity 1/846 23/18639 0.0434782608695652 0.95790934320074 0.656655099679241 0.885906812422467 GO:0016493 C-C chemokine receptor activity 1/846 23/18639 0.0434782608695652 0.95790934320074 0.656655099679241 0.885906812422467 GO:0017134 fibroblast growth factor binding 1/846 23/18639 0.0434782608695652 0.95790934320074 0.656655099679241 0.885906812422467 GO:0031681 G-protein beta-subunit binding 1/846 23/18639 0.0434782608695652 0.95790934320074 0.656655099679241 0.885906812422467 GO:0042171 lysophosphatidic acid acyltransferase activity 1/846 23/18639 0.0434782608695652 0.95790934320074 0.656655099679241 0.885906812422467 GO:0043274 phospholipase binding 1/846 23/18639 0.0434782608695652 0.95790934320074 0.656655099679241 0.885906812422467 GO:0070577 lysine-acetylated histone binding 1/846 23/18639 0.0434782608695652 0.95790934320074 0.656655099679241 0.885906812422467 GO:0071617 lysophospholipid acyltransferase activity 1/846 23/18639 0.0434782608695652 0.95790934320074 0.656655099679241 0.885906812422467 GO:0099186 structural constituent of postsynapse 1/846 23/18639 0.0434782608695652 0.95790934320074 0.656655099679241 0.885906812422467 GO:0140102 catalytic activity, acting on a rRNA 1/846 23/18639 0.0434782608695652 0.95790934320074 0.656655099679241 0.885906812422467 GO:0048020 CCR chemokine receptor binding 2/846 50/18639 0.04 0.881276595744681 0.669335919088363 0.896044863220429 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/846 24/18639 0.0416666666666667 0.917996453900709 0.672258332686942 0.896044863220429 GO:0004622 lysophospholipase activity 1/846 24/18639 0.0416666666666667 0.917996453900709 0.672258332686942 0.896044863220429 GO:0005315 phosphate transmembrane transporter activity 1/846 24/18639 0.0416666666666667 0.917996453900709 0.672258332686942 0.896044863220429 GO:0015295 solute:proton symporter activity 1/846 24/18639 0.0416666666666667 0.917996453900709 0.672258332686942 0.896044863220429 GO:0019957 C-C chemokine binding 1/846 24/18639 0.0416666666666667 0.917996453900709 0.672258332686942 0.896044863220429 GO:0048027 mRNA 5'-UTR binding 1/846 24/18639 0.0416666666666667 0.917996453900709 0.672258332686942 0.896044863220429 GO:0140033 acetylation-dependent protein binding 1/846 24/18639 0.0416666666666667 0.917996453900709 0.672258332686942 0.896044863220429 GO:0140612 DNA damage sensor activity 1/846 24/18639 0.0416666666666667 0.917996453900709 0.672258332686942 0.896044863220429 GO:0016758 hexosyltransferase activity 8/846 197/18639 0.0406091370558376 0.894697051517442 0.675798271662056 0.899560583240413 GO:0005272 sodium channel activity 2/846 51/18639 0.0392156862745098 0.863996662494785 0.679925004563312 0.902624269431075 GO:0003724 RNA helicase activity 3/846 77/18639 0.038961038961039 0.858386294556507 0.685213134939921 0.902624269431075 GO:0051540 metal cluster binding 3/846 77/18639 0.038961038961039 0.858386294556507 0.685213134939921 0.902624269431075 GO:0015171 amino acid transmembrane transporter activity 4/846 102/18639 0.0392156862745098 0.863996662494785 0.685928777665161 0.902624269431075 GO:0004709 MAP kinase kinase kinase activity 1/846 25/18639 0.04 0.881276595744681 0.687153280339204 0.902624269431075 GO:0008483 transaminase activity 1/846 25/18639 0.04 0.881276595744681 0.687153280339204 0.902624269431075 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/846 25/18639 0.04 0.881276595744681 0.687153280339204 0.902624269431075 GO:0017025 TBP-class protein binding 1/846 25/18639 0.04 0.881276595744681 0.687153280339204 0.902624269431075 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/846 25/18639 0.04 0.881276595744681 0.687153280339204 0.902624269431075 GO:0019707 protein-cysteine S-acyltransferase activity 1/846 25/18639 0.04 0.881276595744681 0.687153280339204 0.902624269431075 GO:0034212 protein N-acetyltransferase activity 2/846 53/18639 0.0377358490566038 0.831393014853473 0.70027070646508 0.905248849962169 GO:0001664 G protein-coupled receptor binding 12/846 297/18639 0.0404040404040404 0.890178379540082 0.700989619502823 0.905248849962169 GO:0001637 G protein-coupled chemoattractant receptor activity 1/846 26/18639 0.0384615384615385 0.847381342062193 0.701372057863273 0.905248849962169 GO:0004950 chemokine receptor activity 1/846 26/18639 0.0384615384615385 0.847381342062193 0.701372057863273 0.905248849962169 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/846 26/18639 0.0384615384615385 0.847381342062193 0.701372057863273 0.905248849962169 GO:0015216 purine nucleotide transmembrane transporter activity 1/846 26/18639 0.0384615384615385 0.847381342062193 0.701372057863273 0.905248849962169 GO:0034237 protein kinase A regulatory subunit binding 1/846 26/18639 0.0384615384615385 0.847381342062193 0.701372057863273 0.905248849962169 GO:0051139 metal cation:proton antiporter activity 1/846 26/18639 0.0384615384615385 0.847381342062193 0.701372057863273 0.905248849962169 GO:0070006 metalloaminopeptidase activity 1/846 26/18639 0.0384615384615385 0.847381342062193 0.701372057863273 0.905248849962169 GO:0097602 cullin family protein binding 1/846 26/18639 0.0384615384615385 0.847381342062193 0.701372057863273 0.905248849962169 GO:0008186 ATP-dependent activity, acting on RNA 3/846 79/18639 0.0379746835443038 0.83665499596014 0.701862949870368 0.905248849962169 GO:0015370 solute:sodium symporter activity 3/846 79/18639 0.0379746835443038 0.83665499596014 0.701862949870368 0.905248849962169 GO:0016835 carbon-oxygen lyase activity 3/846 79/18639 0.0379746835443038 0.83665499596014 0.701862949870368 0.905248849962169 GO:0046332 SMAD binding 3/846 79/18639 0.0379746835443038 0.83665499596014 0.701862949870368 0.905248849962169 GO:0005319 lipid transporter activity 7/846 178/18639 0.0393258426966292 0.866423619411905 0.703179783335899 0.905775509025699 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/846 27/18639 0.037037037037037 0.815996847911741 0.714945325958028 0.915019884441789 GO:0016405 CoA-ligase activity 1/846 27/18639 0.037037037037037 0.815996847911741 0.714945325958028 0.915019884441789 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/846 27/18639 0.037037037037037 0.815996847911741 0.714945325958028 0.915019884441789 GO:0035255 ionotropic glutamate receptor binding 1/846 27/18639 0.037037037037037 0.815996847911741 0.714945325958028 0.915019884441789 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/846 27/18639 0.037037037037037 0.815996847911741 0.714945325958028 0.915019884441789 GO:0030971 receptor tyrosine kinase binding 3/846 81/18639 0.037037037037037 0.815996847911741 0.71783313313844 0.917355639826152 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 7/846 181/18639 0.0386740331491713 0.852063006935465 0.719405623702812 0.917355639826152 GO:0098632 cell-cell adhesion mediator activity 2/846 55/18639 0.0363636363636364 0.801160541586073 0.719530702451405 0.917355639826152 GO:0005179 hormone activity 5/846 132/18639 0.0378787878787879 0.834542230818827 0.720929539957058 0.917965199664351 GO:0005242 inward rectifier potassium channel activity 1/846 28/18639 0.0357142857142857 0.786854103343465 0.727902356596299 0.9197955000336 GO:0019789 SUMO transferase activity 1/846 28/18639 0.0357142857142857 0.786854103343465 0.727902356596299 0.9197955000336 GO:0046966 nuclear thyroid hormone receptor binding 1/846 28/18639 0.0357142857142857 0.786854103343465 0.727902356596299 0.9197955000336 GO:0051019 mitogen-activated protein kinase binding 1/846 28/18639 0.0357142857142857 0.786854103343465 0.727902356596299 0.9197955000336 GO:0051959 dynein light intermediate chain binding 1/846 28/18639 0.0357142857142857 0.786854103343465 0.727902356596299 0.9197955000336 GO:0141052 histone H3 demethylase activity 1/846 28/18639 0.0357142857142857 0.786854103343465 0.727902356596299 0.9197955000336 GO:0004620 phospholipase activity 4/846 109/18639 0.036697247706422 0.808510638297872 0.734793541515051 0.924875040809701 GO:0015297 antiporter activity 5/846 135/18639 0.037037037037037 0.815996847911741 0.738955709293235 0.924875040809701 GO:0016755 aminoacyltransferase activity 20/846 496/18639 0.0403225806451613 0.888383665065202 0.739149629698745 0.924875040809701 GO:0003785 actin monomer binding 1/846 29/18639 0.0344827586206897 0.759721203228173 0.740271095853702 0.924875040809701 GO:0005416 amino acid:monoatomic cation symporter activity 1/846 29/18639 0.0344827586206897 0.759721203228173 0.740271095853702 0.924875040809701 GO:0016417 S-acyltransferase activity 1/846 29/18639 0.0344827586206897 0.759721203228173 0.740271095853702 0.924875040809701 GO:0035250 UDP-galactosyltransferase activity 1/846 29/18639 0.0344827586206897 0.759721203228173 0.740271095853702 0.924875040809701 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/846 29/18639 0.0344827586206897 0.759721203228173 0.740271095853702 0.924875040809701 GO:0106222 lncRNA binding 1/846 29/18639 0.0344827586206897 0.759721203228173 0.740271095853702 0.924875040809701 GO:0016779 nucleotidyltransferase activity 5/846 136/18639 0.0367647058823529 0.809996871088861 0.74477140021449 0.92586273069542 GO:0044325 transmembrane transporter binding 5/846 136/18639 0.0367647058823529 0.809996871088861 0.74477140021449 0.92586273069542 GO:0008083 growth factor activity 6/846 162/18639 0.037037037037037 0.815996847911741 0.749524750504525 0.92586273069542 GO:0008187 poly-pyrimidine tract binding 1/846 30/18639 0.0333333333333333 0.734397163120567 0.752078223898182 0.92586273069542 GO:0015215 nucleotide transmembrane transporter activity 1/846 30/18639 0.0333333333333333 0.734397163120567 0.752078223898182 0.92586273069542 GO:0032452 histone demethylase activity 1/846 30/18639 0.0333333333333333 0.734397163120567 0.752078223898182 0.92586273069542 GO:0051721 protein phosphatase 2A binding 1/846 30/18639 0.0333333333333333 0.734397163120567 0.752078223898182 0.92586273069542 GO:0070566 adenylyltransferase activity 1/846 30/18639 0.0333333333333333 0.734397163120567 0.752078223898182 0.92586273069542 GO:0098918 structural constituent of synapse 1/846 30/18639 0.0333333333333333 0.734397163120567 0.752078223898182 0.92586273069542 GO:0046943 carboxylic acid transmembrane transporter activity 7/846 188/18639 0.0372340425531915 0.820337256677229 0.754883869888335 0.92586273069542 GO:0140597 protein carrier chaperone 7/846 188/18639 0.0372340425531915 0.820337256677229 0.754883869888335 0.92586273069542 GO:0070063 RNA polymerase binding 2/846 59/18639 0.0338983050847458 0.746844572664984 0.754925439155143 0.92586273069542 GO:0005342 organic acid transmembrane transporter activity 7/846 189/18639 0.037037037037037 0.815996847911741 0.759679410407011 0.92586273069542 GO:0019787 ubiquitin-like protein transferase activity 19/846 479/18639 0.0396659707724426 0.873917292231155 0.759707009572905 0.92586273069542 GO:0140713 histone chaperone activity 6/846 164/18639 0.0365853658536585 0.806045666839647 0.759864937700135 0.92586273069542 GO:0030295 protein kinase activator activity 5/846 139/18639 0.0359712230215827 0.792514924230828 0.761643173464852 0.92586273069542 GO:0070851 growth factor receptor binding 5/846 139/18639 0.0359712230215827 0.792514924230828 0.761643173464852 0.92586273069542 GO:0001098 basal transcription machinery binding 2/846 60/18639 0.0333333333333333 0.734397163120567 0.763149195337632 0.92586273069542 GO:0001099 basal RNA polymerase II transcription machinery binding 2/846 60/18639 0.0333333333333333 0.734397163120567 0.763149195337632 0.92586273069542 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/846 31/18639 0.032258064516129 0.710706932052162 0.76334921226844 0.92586273069542 GO:0016411 acylglycerol O-acyltransferase activity 1/846 31/18639 0.032258064516129 0.710706932052162 0.76334921226844 0.92586273069542 GO:0016878 acid-thiol ligase activity 1/846 31/18639 0.032258064516129 0.710706932052162 0.76334921226844 0.92586273069542 GO:0072349 modified amino acid transmembrane transporter activity 1/846 31/18639 0.032258064516129 0.710706932052162 0.76334921226844 0.92586273069542 GO:0140457 protein demethylase activity 1/846 31/18639 0.032258064516129 0.710706932052162 0.76334921226844 0.92586273069542 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/846 32/18639 0.03125 0.688497340425532 0.774108378563631 0.935178145785276 GO:0042910 xenobiotic transmembrane transporter activity 1/846 32/18639 0.03125 0.688497340425532 0.774108378563631 0.935178145785276 GO:0043425 bHLH transcription factor binding 1/846 32/18639 0.03125 0.688497340425532 0.774108378563631 0.935178145785276 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 6/846 167/18639 0.0359281437125748 0.791565804561091 0.77478149289733 0.935178145785276 GO:0016757 glycosyltransferase activity 10/846 267/18639 0.0374531835205993 0.825165351820862 0.775866284286971 0.935355121443906 GO:0015294 solute:monoatomic cation symporter activity 4/846 116/18639 0.0344827586206897 0.759721203228173 0.777705812195328 0.936440452607177 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/846 33/18639 0.0303030303030303 0.667633784655061 0.784378938661184 0.941065946865464 GO:0019239 deaminase activity 1/846 33/18639 0.0303030303030303 0.667633784655061 0.784378938661184 0.941065946865464 GO:0019956 chemokine binding 1/846 33/18639 0.0303030303030303 0.667633784655061 0.784378938661184 0.941065946865464 GO:0008194 UDP-glycosyltransferase activity 5/846 145/18639 0.0344827586206897 0.759721203228173 0.792838080728401 0.942619651672192 GO:0008175 tRNA methyltransferase activity 1/846 34/18639 0.0294117647058824 0.647997496871089 0.794183056574364 0.942619651672192 GO:0015020 glucuronosyltransferase activity 1/846 34/18639 0.0294117647058824 0.647997496871089 0.794183056574364 0.942619651672192 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/846 34/18639 0.0294117647058824 0.647997496871089 0.794183056574364 0.942619651672192 GO:0016831 carboxy-lyase activity 1/846 34/18639 0.0294117647058824 0.647997496871089 0.794183056574364 0.942619651672192 GO:0030332 cyclin binding 1/846 34/18639 0.0294117647058824 0.647997496871089 0.794183056574364 0.942619651672192 GO:0051427 hormone receptor binding 1/846 34/18639 0.0294117647058824 0.647997496871089 0.794183056574364 0.942619651672192 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/846 34/18639 0.0294117647058824 0.647997496871089 0.794183056574364 0.942619651672192 GO:0090482 vitamin transmembrane transporter activity 1/846 34/18639 0.0294117647058824 0.647997496871089 0.794183056574364 0.942619651672192 GO:0051219 phosphoprotein binding 3/846 93/18639 0.032258064516129 0.710706932052162 0.799969669178866 0.945845650979874 GO:0061659 ubiquitin-like protein ligase activity 14/846 372/18639 0.0376344086021505 0.829158087394189 0.800154683971854 0.945845650979874 GO:0000175 3'-5'-RNA exonuclease activity 1/846 35/18639 0.0285714285714286 0.629483282674772 0.803541892056121 0.945845650979874 GO:0005343 organic acid:sodium symporter activity 1/846 35/18639 0.0285714285714286 0.629483282674772 0.803541892056121 0.945845650979874 GO:0010485 histone H4 acetyltransferase activity 1/846 35/18639 0.0285714285714286 0.629483282674772 0.803541892056121 0.945845650979874 GO:0016229 steroid dehydrogenase activity 1/846 35/18639 0.0285714285714286 0.629483282674772 0.803541892056121 0.945845650979874 GO:0043015 gamma-tubulin binding 1/846 35/18639 0.0285714285714286 0.629483282674772 0.803541892056121 0.945845650979874 GO:0003697 single-stranded DNA binding 4/846 121/18639 0.0330578512396694 0.728327765078249 0.804857659184858 0.946277224301065 GO:0019209 kinase activator activity 5/846 148/18639 0.0337837837837838 0.744321449108683 0.80719346287075 0.947149860127711 GO:0008528 G protein-coupled peptide receptor activity 4/846 122/18639 0.0327868852459016 0.722357865364493 0.809952107002184 0.947149860127711 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 4/846 122/18639 0.0327868852459016 0.722357865364493 0.809952107002184 0.947149860127711 GO:0008276 protein methyltransferase activity 3/846 95/18639 0.0315789473684211 0.695744680851064 0.811511831224945 0.947149860127711 GO:0004190 aspartic-type endopeptidase activity 1/846 36/18639 0.0277777777777778 0.611997635933806 0.812475646050989 0.947149860127711 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/846 36/18639 0.0277777777777778 0.611997635933806 0.812475646050989 0.947149860127711 GO:0045505 dynein intermediate chain binding 1/846 36/18639 0.0277777777777778 0.611997635933806 0.812475646050989 0.947149860127711 GO:0008173 RNA methyltransferase activity 2/846 67/18639 0.0298507462686567 0.657669101302001 0.814255914730771 0.947149860127711 GO:0030145 manganese ion binding 2/846 68/18639 0.0294117647058824 0.647997496871089 0.820693644235868 0.947149860127711 GO:0000510 H3-H4 histone complex chaperone activity 5/846 151/18639 0.033112582781457 0.729533605748908 0.820747565172844 0.947149860127711 GO:0140584 chromatin extrusion motor activity 5/846 151/18639 0.033112582781457 0.729533605748908 0.820747565172844 0.947149860127711 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/846 151/18639 0.033112582781457 0.729533605748908 0.820747565172844 0.947149860127711 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/846 151/18639 0.033112582781457 0.729533605748908 0.820747565172844 0.947149860127711 GO:0022829 wide pore channel activity 1/846 37/18639 0.027027027027027 0.595457159286947 0.821003604092212 0.947149860127711 GO:0030280 structural constituent of skin epidermis 1/846 37/18639 0.027027027027027 0.595457159286947 0.821003604092212 0.947149860127711 GO:0070001 aspartic-type peptidase activity 1/846 37/18639 0.027027027027027 0.595457159286947 0.821003604092212 0.947149860127711 GO:0008168 methyltransferase activity 7/846 204/18639 0.0343137254901961 0.755997079682937 0.823586218379913 0.947149860127711 GO:0015616 DNA translocase activity 5/846 152/18639 0.0328947368421053 0.724734042553192 0.825091495810582 0.947149860127711 GO:0140674 ATP-dependent histone chaperone activity 5/846 152/18639 0.0328947368421053 0.724734042553192 0.825091495810582 0.947149860127711 GO:0008080 N-acetyltransferase activity 2/846 69/18639 0.0289855072463768 0.638606228800493 0.826930515640816 0.947149860127711 GO:0016279 protein-lysine N-methyltransferase activity 2/846 69/18639 0.0289855072463768 0.638606228800493 0.826930515640816 0.947149860127711 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/846 38/18639 0.0263157894736842 0.579787234042553 0.829144177736873 0.947149860127711 GO:0042887 amide transmembrane transporter activity 1/846 38/18639 0.0263157894736842 0.579787234042553 0.829144177736873 0.947149860127711 GO:0003774 cytoskeletal motor activity 5/846 153/18639 0.0326797385620915 0.719997218745654 0.829349877524064 0.947149860127711 GO:0061775 cohesin loader activity 5/846 153/18639 0.0326797385620915 0.719997218745654 0.829349877524064 0.947149860127711 GO:0016278 lysine N-methyltransferase activity 2/846 70/18639 0.0285714285714286 0.629483282674772 0.832971473537933 0.950197436061006 GO:0004386 helicase activity 5/846 155/18639 0.032258064516129 0.710706932052162 0.837613762072112 0.953843833925376 GO:0001653 peptide receptor activity 4/846 128/18639 0.03125 0.688497340425532 0.838275827692038 0.953843833925376 GO:0004532 RNA exonuclease activity 1/846 40/18639 0.025 0.550797872340426 0.844332683765703 0.953843833925376 GO:0032451 demethylase activity 1/846 40/18639 0.025 0.550797872340426 0.844332683765703 0.953843833925376 GO:0061791 GTPase motor activity 1/846 40/18639 0.025 0.550797872340426 0.844332683765703 0.953843833925376 GO:0071855 neuropeptide receptor binding 1/846 40/18639 0.025 0.550797872340426 0.844332683765703 0.953843833925376 GO:1990606 membrane scission GTPase motor activity 1/846 40/18639 0.025 0.550797872340426 0.844332683765703 0.953843833925376 GO:0016298 lipase activity 4/846 130/18639 0.0307692307692308 0.677905073649754 0.846896174207581 0.953843833925376 GO:0140658 ATP-dependent chromatin remodeler activity 5/846 158/18639 0.0316455696202532 0.69721249663345 0.849392035364508 0.953843833925376 GO:0043539 protein serine/threonine kinase activator activity 2/846 73/18639 0.0273972602739726 0.603614106674439 0.849967752807518 0.953843833925376 GO:0004812 aminoacyl-tRNA ligase activity 1/846 41/18639 0.024390243902439 0.537363777893098 0.851413416575758 0.953843833925376 GO:0008227 G protein-coupled amine receptor activity 1/846 41/18639 0.024390243902439 0.537363777893098 0.851413416575758 0.953843833925376 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/846 41/18639 0.024390243902439 0.537363777893098 0.851413416575758 0.953843833925376 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/846 41/18639 0.024390243902439 0.537363777893098 0.851413416575758 0.953843833925376 GO:0140828 metal cation:monoatomic cation antiporter activity 1/846 41/18639 0.024390243902439 0.537363777893098 0.851413416575758 0.953843833925376 GO:0003684 damaged DNA binding 2/846 74/18639 0.027027027027027 0.595457159286947 0.855273710783664 0.953843833925376 GO:0035064 methylated histone binding 2/846 74/18639 0.027027027027027 0.595457159286947 0.855273710783664 0.953843833925376 GO:0016887 ATP hydrolysis activity 15/846 417/18639 0.0359712230215827 0.792514924230828 0.855305772516541 0.953843833925376 GO:0003689 DNA clamp loader activity 5/846 160/18639 0.03125 0.688497340425532 0.85684429392263 0.953843833925376 GO:0004402 histone acetyltransferase activity 1/846 42/18639 0.0238095238095238 0.524569402228977 0.858172436340083 0.953843833925376 GO:0004520 DNA endonuclease activity 1/846 42/18639 0.0238095238095238 0.524569402228977 0.858172436340083 0.953843833925376 GO:0043175 RNA polymerase core enzyme binding 1/846 42/18639 0.0238095238095238 0.524569402228977 0.858172436340083 0.953843833925376 GO:0051879 Hsp90 protein binding 1/846 42/18639 0.0238095238095238 0.524569402228977 0.858172436340083 0.953843833925376 GO:0016741 transferase activity, transferring one-carbon groups 7/846 215/18639 0.0325581395348837 0.717318159327066 0.861375530875494 0.956337866684708 GO:0051087 protein-folding chaperone binding 4/846 134/18639 0.0298507462686567 0.657669101302001 0.862975893772028 0.956517329292132 GO:0008375 acetylglucosaminyltransferase activity 1/846 43/18639 0.0232558139534884 0.512370113805047 0.864624343575459 0.956517329292132 GO:0051536 iron-sulfur cluster binding 2/846 76/18639 0.0263157894736842 0.579787234042553 0.865374755287365 0.956517329292132 GO:0140034 methylation-dependent protein binding 2/846 76/18639 0.0263157894736842 0.579787234042553 0.865374755287365 0.956517329292132 GO:0015081 sodium ion transmembrane transporter activity 5/846 164/18639 0.0304878048780488 0.671704722366373 0.870826635055715 0.960611016538865 GO:0004842 ubiquitin-protein transferase activity 16/846 449/18639 0.0356347438752784 0.785101644315974 0.871005375076363 0.960611016538865 GO:0140303 intramembrane lipid transporter activity 1/846 45/18639 0.0222222222222222 0.489598108747045 0.876661943119678 0.965781168276596 GO:0005525 GTP binding 13/846 378/18639 0.0343915343915344 0.757711358775189 0.880893354415265 0.968446392033492 GO:0140767 enzyme-substrate adaptor activity 4/846 139/18639 0.0287769784172662 0.634011939384663 0.881023949422645 0.968446392033492 GO:0061630 ubiquitin protein ligase activity 12/846 353/18639 0.0339943342776204 0.748960279669701 0.882116788675366 0.968579777873723 GO:0061733 protein-lysine-acetyltransferase activity 1/846 47/18639 0.0212765957446809 0.468764146672703 0.887630311873052 0.970627359802723 GO:0061749 forked DNA-dependent helicase activity 1/846 47/18639 0.0212765957446809 0.468764146672703 0.887630311873052 0.970627359802723 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/846 47/18639 0.0212765957446809 0.468764146672703 0.887630311873052 0.970627359802723 GO:0003924 GTPase activity 11/846 331/18639 0.0332326283987915 0.732178440573375 0.8903736537463 0.970627359802723 GO:0009378 four-way junction helicase activity 1/846 48/18639 0.0208333333333333 0.458998226950355 0.89274351949759 0.970627359802723 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/846 48/18639 0.0208333333333333 0.458998226950355 0.89274351949759 0.970627359802723 GO:0036121 double-stranded DNA helicase activity 1/846 48/18639 0.0208333333333333 0.458998226950355 0.89274351949759 0.970627359802723 GO:0038187 pattern recognition receptor activity 1/846 48/18639 0.0208333333333333 0.458998226950355 0.89274351949759 0.970627359802723 GO:0043138 3'-5' DNA helicase activity 1/846 48/18639 0.0208333333333333 0.458998226950355 0.89274351949759 0.970627359802723 GO:0005254 chloride channel activity 2/846 83/18639 0.0240963855421687 0.530889515508844 0.895837129962803 0.972751574056654 GO:0016763 pentosyltransferase activity 1/846 49/18639 0.0204081632653061 0.449630916196266 0.897624321095408 0.972751574056654 GO:0060590 ATPase regulator activity 1/846 49/18639 0.0204081632653061 0.449630916196266 0.897624321095408 0.972751574056654 GO:0004527 exonuclease activity 2/846 84/18639 0.0238095238095238 0.524569402228977 0.899625056992005 0.97386121804672 GO:0015605 organophosphate ester transmembrane transporter activity 1/846 50/18639 0.02 0.44063829787234 0.902283268075143 0.97518541215476 GO:0015293 symporter activity 4/846 146/18639 0.0273972602739726 0.603614106674439 0.902804549066041 0.97518541215476 GO:0016830 carbon-carbon lyase activity 1/846 51/18639 0.0196078431372549 0.431998331247393 0.90673043334538 0.978366062819636 GO:0015291 secondary active transmembrane transporter activity 9/846 287/18639 0.0313588850174216 0.690896285862555 0.90838124011812 0.979087671781368 GO:0030159 signaling receptor complex adaptor activity 1/846 52/18639 0.0192307692307692 0.423690671031097 0.910975432989764 0.979895128486046 GO:0005246 calcium channel regulator activity 1/846 53/18639 0.0188679245283019 0.415696507426736 0.915027446961393 0.979895128486046 GO:0005544 calcium-dependent phospholipid binding 1/846 53/18639 0.0188679245283019 0.415696507426736 0.915027446961393 0.979895128486046 GO:0051018 protein kinase A binding 1/846 53/18639 0.0188679245283019 0.415696507426736 0.915027446961393 0.979895128486046 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/846 53/18639 0.0188679245283019 0.415696507426736 0.915027446961393 0.979895128486046 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/846 53/18639 0.0188679245283019 0.415696507426736 0.915027446961393 0.979895128486046 GO:0015108 chloride transmembrane transporter activity 3/846 121/18639 0.0247933884297521 0.546245823808686 0.916766300562375 0.980703864442798 GO:0008094 ATP-dependent activity, acting on DNA 6/846 210/18639 0.0285714285714286 0.629483282674772 0.919093585631441 0.982139662244959 GO:0019001 guanyl nucleotide binding 13/846 400/18639 0.0325 0.716037234042553 0.921074996278673 0.982151627047954 GO:0032561 guanyl ribonucleotide binding 13/846 400/18639 0.0325 0.716037234042553 0.921074996278673 0.982151627047954 GO:0008374 O-acyltransferase activity 1/846 55/18639 0.0181818181818182 0.400580270793037 0.922587174699863 0.982269050413515 GO:0008514 organic anion transmembrane transporter activity 8/846 269/18639 0.0297397769516729 0.655224234754409 0.92547964810781 0.982269050413515 GO:0030170 pyridoxal phosphate binding 1/846 56/18639 0.0178571428571429 0.393427051671733 0.926111241112041 0.982269050413515 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/846 56/18639 0.0178571428571429 0.393427051671733 0.926111241112041 0.982269050413515 GO:0170055 lipid transmembrane transporter activity 1/846 56/18639 0.0178571428571429 0.393427051671733 0.926111241112041 0.982269050413515 GO:0004175 endopeptidase activity 13/846 405/18639 0.0320987654320988 0.707197268190176 0.928417919698374 0.982700569629367 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/846 57/18639 0.0175438596491228 0.386524822695035 0.929475062347536 0.982700569629367 GO:0070279 vitamin B6 binding 1/846 57/18639 0.0175438596491228 0.386524822695035 0.929475062347536 0.982700569629367 GO:0008408 3'-5' exonuclease activity 1/846 58/18639 0.0172413793103448 0.379860601614087 0.932685916790222 0.984008316444287 GO:0017116 single-stranded DNA helicase activity 1/846 58/18639 0.0172413793103448 0.379860601614087 0.932685916790222 0.984008316444287 GO:0036002 pre-mRNA binding 1/846 59/18639 0.0169491525423729 0.373422286332492 0.935750752611516 0.985970791307874 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/846 60/18639 0.0166666666666667 0.367198581560284 0.938676202734803 0.985970791307874 GO:0031072 heat shock protein binding 3/846 131/18639 0.0229007633587786 0.504547669319474 0.940339651452775 0.985970791307874 GO:0005249 voltage-gated potassium channel activity 2/846 98/18639 0.0204081632653061 0.449630916196266 0.940781209853129 0.985970791307874 GO:0008170 N-methyltransferase activity 2/846 98/18639 0.0204081632653061 0.449630916196266 0.940781209853129 0.985970791307874 GO:0042626 ATPase-coupled transmembrane transporter activity 2/846 98/18639 0.0204081632653061 0.449630916196266 0.940781209853129 0.985970791307874 GO:0016836 hydro-lyase activity 1/846 61/18639 0.0163934426229508 0.361178932682246 0.941468599122464 0.985970791307874 GO:0140097 catalytic activity, acting on DNA 10/846 336/18639 0.0297619047619048 0.655711752786221 0.943628299573741 0.986148246457391 GO:0015103 inorganic anion transmembrane transporter activity 4/846 165/18639 0.0242424242424242 0.534107027724049 0.945169591899013 0.986148246457391 GO:0022824 transmitter-gated monoatomic ion channel activity 1/846 63/18639 0.0158730158730159 0.349712934819318 0.946678134959629 0.986148246457391 GO:0022835 transmitter-gated channel activity 1/846 63/18639 0.0158730158730159 0.349712934819318 0.946678134959629 0.986148246457391 GO:1901682 sulfur compound transmembrane transporter activity 1/846 63/18639 0.0158730158730159 0.349712934819318 0.946678134959629 0.986148246457391 GO:0004536 DNA nuclease activity 1/846 64/18639 0.015625 0.344248670212766 0.949106553231817 0.986148246457391 GO:0099094 ligand-gated monoatomic cation channel activity 3/846 136/18639 0.0220588235294118 0.485998122653317 0.949653089521672 0.986148246457391 GO:0005253 monoatomic anion channel activity 2/846 103/18639 0.0194174757281553 0.427804172691593 0.951132027971741 0.986148246457391 GO:0016922 nuclear receptor binding 3/846 137/18639 0.0218978102189781 0.482450691101103 0.951345303026828 0.986148246457391 GO:0016829 lyase activity 5/846 200/18639 0.025 0.550797872340426 0.952166720542895 0.986148246457391 GO:0000287 magnesium ion binding 6/846 230/18639 0.0260869565217391 0.574745605920444 0.952518316287329 0.986148246457391 GO:0140101 catalytic activity, acting on a tRNA 3/846 139/18639 0.0215827338129496 0.475508954538497 0.954571704005811 0.987182931601642 GO:0004497 monooxygenase activity 2/846 106/18639 0.0188679245283019 0.415696507426736 0.956488176456556 0.987182931601642 GO:0008013 beta-catenin binding 2/846 106/18639 0.0188679245283019 0.415696507426736 0.956488176456556 0.987182931601642 GO:0003777 microtubule motor activity 1/846 68/18639 0.0147058823529412 0.323998748435544 0.957764577799519 0.987478060047694 GO:0098960 postsynaptic neurotransmitter receptor activity 1/846 69/18639 0.0144927536231884 0.319303114400247 0.959688608125382 0.988439609815089 GO:0016782 transferase activity, transferring sulphur-containing groups 1/846 70/18639 0.0142857142857143 0.314741641337386 0.961525088336795 0.989242035848533 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 7/846 268/18639 0.0261194029850746 0.575460463639251 0.962452131166577 0.989242035848533 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/846 73/18639 0.0136986301369863 0.301807053337219 0.966548126517722 0.991950890320477 GO:0008509 monoatomic anion transmembrane transporter activity 3/846 149/18639 0.0201342281879195 0.443595601884906 0.967908655387921 0.991950890320477 GO:0003678 DNA helicase activity 1/846 74/18639 0.0135135135135135 0.297728579643473 0.968072433582572 0.991950890320477 GO:0001217 DNA-binding transcription repressor activity 7/846 278/18639 0.0251798561151079 0.55476044696158 0.971324261589096 0.994261076801159 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 14/846 484/18639 0.0289256198347107 0.637286794443468 0.975794684754162 0.997261445681669 GO:0008236 serine-type peptidase activity 4/846 194/18639 0.0206185567010309 0.45426628646633 0.978361759756757 0.997261445681669 GO:0005267 potassium channel activity 2/846 124/18639 0.0161290322580645 0.355353466026081 0.978562722098762 0.997261445681669 GO:0030165 PDZ domain binding 1/846 83/18639 0.0120481927710843 0.265444757754422 0.979019110973299 0.997261445681669 GO:0001216 DNA-binding transcription activator activity 14/846 491/18639 0.0285132382892057 0.628201239329202 0.979256725498851 0.997261445681669 GO:0017171 serine hydrolase activity 4/846 198/18639 0.0202020202020202 0.445089189770041 0.98105225674749 0.998070510180865 GO:0035591 signaling adaptor activity 2/846 129/18639 0.0155038759689922 0.341580075870031 0.982443414563212 0.998466956492887 GO:0052689 carboxylic ester hydrolase activity 1/846 92/18639 0.0108695652173913 0.239477335800185 0.986215487826684 0.999996601670748 GO:0030594 neurotransmitter receptor activity 1/846 97/18639 0.0103092783505155 0.227133143233165 0.989085575057619 0.999996601670748 GO:0022843 voltage-gated monoatomic cation channel activity 2/846 143/18639 0.013986013986014 0.308138669840797 0.990023521855119 0.999996601670748 GO:0015276 ligand-gated monoatomic ion channel activity 3/846 186/18639 0.0161290322580645 0.355353466026081 0.991604037527061 0.999996601670748 GO:0022834 ligand-gated channel activity 3/846 188/18639 0.0159574468085106 0.351573110004527 0.9922073529474 0.999996601670748 GO:0003730 mRNA 3'-UTR binding 5/846 262/18639 0.0190839694656489 0.420456391099561 0.993083084779845 0.999996601670748 GO:0015079 potassium ion transmembrane transporter activity 2/846 160/18639 0.0125 0.275398936170213 0.995029500127475 0.999996601670748 GO:0005244 voltage-gated monoatomic ion channel activity 2/846 173/18639 0.0115606936416185 0.254704218423318 0.99710154314038 0.999996601670748 GO:0022832 voltage-gated channel activity 2/846 175/18639 0.0114285714285714 0.251793313069909 0.997333545545116 0.999996601670748 GO:0004252 serine-type endopeptidase activity 2/846 176/18639 0.0113636363636364 0.250362669245648 0.997442597196966 0.999996601670748 GO:0005261 monoatomic cation channel activity 6/846 341/18639 0.0175953079178886 0.387658326573907 0.99843174723474 0.999996601670748 GO:0046873 metal ion transmembrane transporter activity 9/846 450/18639 0.02 0.44063829787234 0.998800840083 0.999996601670748 GO:0005216 monoatomic ion channel activity 8/846 448/18639 0.0178571428571429 0.393427051671733 0.99955218048867 0.999996601670748 GO:0045182 translation regulator activity 5/846 356/18639 0.0140449438202247 0.309437006932823 0.999741042385319 0.999996601670748 GO:0022836 gated channel activity 4/846 318/18639 0.0125786163522013 0.277131004951158 0.999752088396854 0.999996601670748 GO:0030371 translation repressor activity 2/846 329/18639 0.0060790273556231 0.133932613335058 0.999996601670748 0.999996601670748