ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0015453 oxidoreduction-driven active transmembrane transporter activity 26/1510 68/18639 0.382352941176471 4.71965329178029 5.27567961018388e-12 6.11451266820311e-09 GO:0008137 NADH dehydrogenase (ubiquinone) activity 18/1510 41/18639 0.439024390243902 5.41918914553384 6.79412875652144e-10 3.93719761440418e-07 GO:0003954 NADH dehydrogenase activity 18/1510 44/18639 0.409090909090909 5.04969897652017 2.73424226096415e-09 7.87242822846436e-07 GO:0022853 active monoatomic ion transmembrane transporter activity 31/1510 118/18639 0.26271186440678 3.24283870243574 2.82915083201963e-09 7.87242822846436e-07 GO:0015399 primary active transmembrane transporter activity 38/1510 166/18639 0.228915662650602 2.82566823585734 3.39621580175339e-09 7.87242822846436e-07 GO:0009055 electron transfer activity 29/1510 116/18639 0.25 3.08592715231788 3.0443471641346e-08 5.88066393871999e-06 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 18/1510 58/18639 0.310344827586207 3.83080612011875 3.98824765182618e-07 6.60339861209506e-05 GO:0016651 oxidoreductase activity, acting on NAD(P)H 22/1510 88/18639 0.25 3.08592715231788 1.37693420875739e-06 0.000199483343493727 GO:0015078 proton transmembrane transporter activity 35/1510 185/18639 0.189189189189189 2.33529622337569 1.87014310393929e-06 0.000240832873051737 GO:0005518 collagen binding 19/1510 72/18639 0.263888888888889 3.25736754966887 2.99255839013114e-06 0.000346837517416199 GO:0023026 MHC class II protein complex binding 11/1510 27/18639 0.407407407407407 5.02891832229581 3.6685983288494e-06 0.000386536860285133 GO:0042277 peptide binding 41/1510 249/18639 0.164658634538153 2.03249820473949 9.96255900964866e-06 0.000945818720975198 GO:0031625 ubiquitin protein ligase binding 47/1510 302/18639 0.155629139072848 1.92104074382703 1.09368987013134e-05 0.000945818720975198 GO:0005201 extracellular matrix structural constituent 31/1510 168/18639 0.18452380952381 2.27770813623463 1.20075882517977e-05 0.000945818720975198 GO:0031593 polyubiquitin modification-dependent protein binding 16/1510 59/18639 0.271186440677966 3.34744640251431 1.22409670531734e-05 0.000945818720975198 GO:0044389 ubiquitin-like protein ligase binding 49/1510 322/18639 0.152173913043478 1.87839044054132 1.33298706339812e-05 0.000965582504049015 GO:0070325 lipoprotein particle receptor binding 11/1510 31/18639 0.354838709677419 4.38002563554796 1.75903511314564e-05 0.00119924805655047 GO:0023023 MHC protein complex binding 12/1510 37/18639 0.324324324324324 4.00336495435833 2.09080709199051e-05 0.00134624745534278 GO:0031994 insulin-like growth factor I binding 7/1510 13/18639 0.538461538461538 6.64661232806928 2.50427619306933e-05 0.00152760847777229 GO:0035615 clathrin adaptor activity 8/1510 18/18639 0.444444444444444 5.48609271523179 3.80695550168644e-05 0.00220613071322729 GO:0140030 modification-dependent protein binding 30/1510 173/18639 0.173410404624277 2.14052750449795 5.59427633690686e-05 0.00308750774975002 GO:0050840 extracellular matrix binding 16/1510 67/18639 0.238805970149254 2.94775130967678 6.75138204419282e-05 0.00355675081328158 GO:0001968 fibronectin binding 10/1510 30/18639 0.333333333333333 4.11456953642384 7.85942342347816e-05 0.00384959439563172 GO:0043021 ribonucleoprotein complex binding 30/1510 177/18639 0.169491525423729 2.09215400157144 8.62988603688368e-05 0.00384959439563172 GO:0002020 protease binding 25/1510 136/18639 0.183823529411765 2.26906408258668 8.63584592635244e-05 0.00384959439563172 GO:0019838 growth factor binding 25/1510 136/18639 0.183823529411765 2.26906408258668 8.63584592635244e-05 0.00384959439563172 GO:0050750 low-density lipoprotein particle receptor binding 9/1510 26/18639 0.346153846153846 4.27282221090168 0.000128863119014775 0.00553156870141203 GO:0140312 cargo adaptor activity 8/1510 21/18639 0.380952380952381 4.70236518448439 0.000141993038842819 0.00587749757210097 GO:0003735 structural constituent of ribosome 29/1510 175/18639 0.165714285714286 2.04552885525071 0.000168458661883211 0.00673253755595314 GO:0005178 integrin binding 27/1510 161/18639 0.167701863354037 2.07006293447411 0.000227844350856499 0.00880238675475608 GO:0097110 scaffold protein binding 15/1510 70/18639 0.214285714285714 2.64508041627247 0.000404548003628026 0.0151248753614478 GO:0005520 insulin-like growth factor binding 7/1510 19/18639 0.368421052631579 4.5476821192053 0.000476219763693457 0.0172480845662724 GO:0043394 proteoglycan binding 10/1510 37/18639 0.27027027027027 3.33613746196528 0.000539966923457735 0.0189642928571974 GO:0032395 MHC class II receptor activity 5/1510 10/18639 0.5 6.17185430463576 0.00061782432477661 0.020519608831945 GO:0005048 signal sequence binding 12/1510 51/18639 0.235294117647059 2.90440202571095 0.000619660318479787 0.020519608831945 GO:0120015 sterol transfer activity 9/1510 32/18639 0.28125 3.47166804635762 0.000742026865598835 0.0238891427008069 GO:0001540 amyloid-beta binding 16/1510 83/18639 0.192771084337349 2.37951009335355 0.000906281686614101 0.0283886614806957 GO:0043130 ubiquitin binding 18/1510 100/18639 0.18 2.22186754966887 0.00103868958564095 0.0306333609761166 GO:0004177 aminopeptidase activity 10/1510 40/18639 0.25 3.08592715231788 0.00105106619938823 0.0306333609761166 GO:0140031 phosphorylation-dependent protein binding 5/1510 11/18639 0.454545454545455 5.61077664057796 0.00105723420107391 0.0306333609761166 GO:0043495 protein-membrane adaptor activity 11/1510 47/18639 0.234042553191489 2.88895307876568 0.00108428121673662 0.0306507787853107 GO:0030021 extracellular matrix structural constituent conferring compression resistance 7/1510 22/18639 0.318181818181818 3.92754364840458 0.00129886611589684 0.0358425197220103 GO:0032182 ubiquitin-like protein binding 20/1510 120/18639 0.166666666666667 2.05728476821192 0.00151714885870666 0.0397025369472373 GO:0035091 phosphatidylinositol binding 38/1510 284/18639 0.133802816901408 1.6516229829307 0.00151819481814371 0.0397025369472373 GO:0048038 quinone binding 6/1510 17/18639 0.352941176470588 4.35660303856642 0.0015856628497006 0.0397025369472373 GO:0043022 ribosome binding 19/1510 112/18639 0.169642857142857 2.0940219962157 0.001589628846941 0.0397025369472373 GO:0045296 cadherin binding 43/1510 334/18639 0.12874251497006 1.5891600904152 0.00167622678808888 0.0397025369472373 GO:0035259 nuclear glucocorticoid receptor binding 5/1510 12/18639 0.416666666666667 5.1432119205298 0.00169194821400549 0.0397025369472373 GO:0016407 acetyltransferase activity 17/1510 96/18639 0.177083333333333 2.18586506622517 0.00170111785521836 0.0397025369472373 GO:0140375 immune receptor activity 24/1510 156/18639 0.153846153846154 1.89903209373408 0.00171279279323716 0.0397025369472373 GO:0016504 peptidase activator activity 12/1510 57/18639 0.210526315789474 2.59867549668874 0.00175683082553397 0.0399248417018405 GO:0038024 cargo receptor activity 13/1510 65/18639 0.2 2.4687417218543 0.00188254611255839 0.0419590566241379 GO:0005543 phospholipid binding 59/1510 497/18639 0.118712273641851 1.46534971417911 0.0019410614037173 0.0424469842812896 GO:0022804 active transmembrane transporter activity 55/1510 457/18639 0.12035010940919 1.48556668164099 0.00200671249383767 0.043069995932553 GO:1990381 ubiquitin-specific protease binding 6/1510 18/18639 0.333333333333333 4.11456953642384 0.00221685563016315 0.0465119071320005 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 44/1510 349/18639 0.126074498567335 1.55622687337521 0.00224733977514411 0.0465119071320005 GO:0003725 double-stranded RNA binding 14/1510 75/18639 0.186666666666667 2.30415894039735 0.0025405778910381 0.0516584171177748 GO:0061134 peptidase regulator activity 31/1510 226/18639 0.13716814159292 1.69316357029831 0.00268124043669728 0.0535785804505542 GO:0019955 cytokine binding 22/1510 144/18639 0.152777777777778 1.88584437086093 0.00284809948148077 0.0559482593056985 GO:0019211 phosphatase activator activity 7/1510 25/18639 0.28 3.45623841059603 0.00295300725976003 0.0561071379354406 GO:0120020 cholesterol transfer activity 7/1510 25/18639 0.28 3.45623841059603 0.00295300725976003 0.0561071379354406 GO:0008191 metalloendopeptidase inhibitor activity 5/1510 14/18639 0.357142857142857 4.40846736045412 0.00372905535766478 0.0692165110621912 GO:0008157 protein phosphatase 1 binding 7/1510 26/18639 0.269230769230769 3.32330616403464 0.00376241604565836 0.0692165110621912 GO:0140597 protein carrier chaperone 26/1510 188/18639 0.138297872340426 1.70710863745244 0.0050606214903342 0.0913449295865308 GO:0140297 DNA-binding transcription factor binding 56/1510 488/18639 0.114754098360656 1.41649115188362 0.00512288215972779 0.0913449295865308 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 7/1510 28/18639 0.25 3.08592715231788 0.00587287643551933 0.103131269526771 GO:0008190 eukaryotic initiation factor 4E binding 4/1510 10/18639 0.4 4.93748344370861 0.00605326030455247 0.103365409664167 GO:0019903 protein phosphatase binding 21/1510 144/18639 0.145833333333333 1.80012417218543 0.0060645796869399 0.103365409664167 GO:0061133 endopeptidase activator activity 6/1510 22/18639 0.272727272727273 3.36646598434678 0.0067327771654347 0.113091141083171 GO:0003743 translation initiation factor activity 10/1510 51/18639 0.196078431372549 2.42033502142579 0.00702533091956485 0.116319407653938 GO:0016922 nuclear receptor binding 20/1510 137/18639 0.145985401459854 1.80200125682796 0.00720122307345816 0.117228500058418 GO:0051117 ATPase binding 14/1510 84/18639 0.166666666666667 2.05728476821192 0.00728501758109941 0.117228500058418 GO:0061135 endopeptidase regulator activity 25/1510 184/18639 0.135869565217391 1.67713432191189 0.0073836760174845 0.117228500058418 GO:1901981 phosphatidylinositol phosphate binding 25/1510 185/18639 0.135135135135135 1.66806873098264 0.0078998668169573 0.123728995146669 GO:0016410 N-acyltransferase activity 15/1510 94/18639 0.159574468085106 1.96974073552205 0.00838225454975199 0.129533773642167 GO:0019107 myristoyltransferase activity 4/1510 11/18639 0.363636363636364 4.48862131246237 0.00890813236368308 0.131042642252886 GO:0032050 clathrin heavy chain binding 4/1510 11/18639 0.363636363636364 4.48862131246237 0.00890813236368308 0.131042642252886 GO:0048185 activin binding 4/1510 11/18639 0.363636363636364 4.48862131246237 0.00890813236368308 0.131042642252886 GO:0140098 catalytic activity, acting on RNA 45/1510 387/18639 0.116279069767442 1.43531495456646 0.00896637413193299 0.131042642252886 GO:0042605 peptide antigen binding 9/1510 45/18639 0.2 2.4687417218543 0.00904522120813706 0.131042642252886 GO:0032977 membrane insertase activity 5/1510 17/18639 0.294117647058824 3.63050253213868 0.00939567743958333 0.134439384598482 GO:0030276 clathrin binding 9/1510 46/18639 0.195652173913043 2.41507342355312 0.0104572882000712 0.144074811546414 GO:0015485 cholesterol binding 10/1510 54/18639 0.185185185185185 2.28587196467991 0.010556771858324 0.144074811546414 GO:0051287 NAD binding 10/1510 54/18639 0.185185185185185 2.28587196467991 0.010556771858324 0.144074811546414 GO:0050431 transforming growth factor beta binding 6/1510 24/18639 0.25 3.08592715231788 0.0105663149106516 0.144074811546414 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 29/1510 229/18639 0.126637554585153 1.56317707278984 0.0108850841365956 0.144770095534379 GO:0019902 phosphatase binding 25/1510 190/18639 0.131578947368421 1.62417218543046 0.0109431938964649 0.144770095534379 GO:0140104 molecular carrier activity 31/1510 249/18639 0.124497991967871 1.53676693529083 0.0109920348636975 0.144770095534379 GO:0140313 molecular sequestering activity 10/1510 55/18639 0.181818181818182 2.24431065623119 0.0119914416644521 0.156158212237078 GO:0000995 RNA polymerase III general transcription initiation factor activity 4/1510 12/18639 0.333333333333333 4.11456953642384 0.0125162244385219 0.158380876931075 GO:0035497 cAMP response element binding 4/1510 12/18639 0.333333333333333 4.11456953642384 0.0125162244385219 0.158380876931075 GO:0031369 translation initiation factor binding 7/1510 32/18639 0.21875 2.70018625827815 0.0125720799634675 0.158380876931075 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 6/1510 25/18639 0.24 2.96249006622517 0.0129705173267226 0.161643328835177 GO:0051020 GTPase binding 37/1510 315/18639 0.117460317460317 1.44989593188269 0.0143316748060583 0.176706501066187 GO:0120013 lipid transfer activity 11/1510 65/18639 0.169230769230769 2.08893530310749 0.0146348937571246 0.17854570383692 GO:0140416 transcription regulator inhibitor activity 7/1510 33/18639 0.212121212121212 2.61836243226972 0.0148690850103295 0.17951322423929 GO:0070006 metalloaminopeptidase activity 6/1510 26/18639 0.230769230769231 2.84854814060112 0.0157329477110418 0.187984395846366 GO:1902936 phosphatidylinositol bisphosphate binding 16/1510 111/18639 0.144144144144144 1.77927331304815 0.0169633315693369 0.200617360090423 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 5/1510 20/18639 0.25 3.08592715231788 0.0192189327162316 0.222747430181124 GO:0043024 ribosomal small subunit binding 5/1510 20/18639 0.25 3.08592715231788 0.0192189327162316 0.222747430181124 GO:0032934 sterol binding 11/1510 68/18639 0.161764705882353 1.99677639267628 0.0201042393213888 0.230701122509798 GO:0016209 antioxidant activity 13/1510 86/18639 0.151162790697674 1.86590944093639 0.020671446900267 0.234884381935386 GO:0005539 glycosaminoglycan binding 29/1510 242/18639 0.119834710743802 1.47920475069783 0.0217901844811201 0.238388301366097 GO:0005545 1-phosphatidylinositol binding 4/1510 14/18639 0.285714285714286 3.52677388836329 0.022221661472174 0.238388301366097 GO:0044548 S100 protein binding 4/1510 14/18639 0.285714285714286 3.52677388836329 0.022221661472174 0.238388301366097 GO:0008080 N-acetyltransferase activity 11/1510 69/18639 0.159420289855072 1.96783760437662 0.0222249563431404 0.238388301366097 GO:0004896 cytokine receptor activity 14/1510 96/18639 0.145833333333333 1.80012417218543 0.0223303752332084 0.238388301366097 GO:0036408 histone H3K14 acetyltransferase activity 6/1510 28/18639 0.214285714285714 2.64508041627247 0.0224232464026019 0.238388301366097 GO:0005080 protein kinase C binding 9/1510 52/18639 0.173076923076923 2.13641110545084 0.0226252917603716 0.238388301366097 GO:0030159 signaling receptor complex adaptor activity 9/1510 52/18639 0.173076923076923 2.13641110545084 0.0226252917603716 0.238388301366097 GO:0051010 microtubule plus-end binding 5/1510 21/18639 0.238095238095238 2.93897824030274 0.0235839737448503 0.241445993504722 GO:0072542 protein phosphatase activator activity 5/1510 21/18639 0.238095238095238 2.93897824030274 0.0235839737448503 0.241445993504722 GO:0034212 protein N-acetyltransferase activity 9/1510 53/18639 0.169811320754717 2.09610146195177 0.0253598688752518 0.241445993504722 GO:0003713 transcription coactivator activity 30/1510 256/18639 0.1171875 1.44652835264901 0.0261433223018421 0.241445993504722 GO:0010484 histone H3 acetyltransferase activity 6/1510 29/18639 0.206896551724138 2.55387074674583 0.0263918275693296 0.241445993504722 GO:0046915 transition metal ion transmembrane transporter activity 8/1510 45/18639 0.177777777777778 2.19443708609272 0.0265258960736653 0.241445993504722 GO:0051539 4 iron, 4 sulfur cluster binding 8/1510 45/18639 0.177777777777778 2.19443708609272 0.0265258960736653 0.241445993504722 GO:0019208 phosphatase regulator activity 16/1510 117/18639 0.136752136752137 1.68802852776363 0.0266389948099951 0.241445993504722 GO:0050661 NADP binding 9/1510 54/18639 0.166666666666667 2.05728476821192 0.0283204882786373 0.241445993504722 GO:0004129 cytochrome-c oxidase activity 4/1510 15/18639 0.266666666666667 3.29165562913907 0.0284025019666079 0.241445993504722 GO:0010181 FMN binding 4/1510 15/18639 0.266666666666667 3.29165562913907 0.0284025019666079 0.241445993504722 GO:0051371 muscle alpha-actinin binding 4/1510 15/18639 0.266666666666667 3.29165562913907 0.0284025019666079 0.241445993504722 GO:0032931 histone H3K56 acetyltransferase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0034062 5'-3' RNA polymerase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0043992 histone H3K9 acetyltransferase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0043993 histone H3K18 acetyltransferase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0043994 histone H3K23 acetyltransferase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0043999 histone H2AK5 acetyltransferase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0044012 histone H2AK9 acetyltransferase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0044014 histone H2BK5 acetyltransferase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0044015 histone H2BK12 acetyltransferase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0044016 histone H3K4 acetyltransferase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0044017 histone H3K27 acetyltransferase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0044018 histone H3K36 acetyltransferase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0046972 histone H4K16 acetyltransferase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0097747 RNA polymerase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0140908 histone H3K122 acetyltransferase activity 5/1510 22/18639 0.227272727272727 2.80538832028898 0.0285402080329137 0.241445993504722 GO:0140658 ATP-dependent chromatin remodeler activity 20/1510 158/18639 0.126582278481013 1.56249476066728 0.0306637467382379 0.251385877956857 GO:0031210 phosphatidylcholine binding 6/1510 30/18639 0.2 2.4687417218543 0.0307996502759911 0.251385877956857 GO:0043995 histone H4K5 acetyltransferase activity 6/1510 30/18639 0.2 2.4687417218543 0.0307996502759911 0.251385877956857 GO:0043996 histone H4K8 acetyltransferase activity 6/1510 30/18639 0.2 2.4687417218543 0.0307996502759911 0.251385877956857 GO:0043997 histone H4K12 acetyltransferase activity 6/1510 30/18639 0.2 2.4687417218543 0.0307996502759911 0.251385877956857 GO:0061733 protein-lysine-acetyltransferase activity 8/1510 47/18639 0.170212765957447 2.10105678455685 0.0335764783480778 0.267200660421258 GO:0043178 alcohol binding 13/1510 92/18639 0.141304347826087 1.74421969478837 0.0339891687452142 0.267200660421258 GO:0004602 glutathione peroxidase activity 5/1510 23/18639 0.217391304347826 2.68341491505903 0.0341081291833004 0.267200660421258 GO:0008171 O-methyltransferase activity 5/1510 23/18639 0.217391304347826 2.68341491505903 0.0341081291833004 0.267200660421258 GO:0044013 histone H2B acetyltransferase activity 5/1510 23/18639 0.217391304347826 2.68341491505903 0.0341081291833004 0.267200660421258 GO:0008135 translation factor activity, RNA binding 12/1510 83/18639 0.144578313253012 1.78463257001516 0.0348047182696005 0.267200660421258 GO:0019843 rRNA binding 10/1510 65/18639 0.153846153846154 1.89903209373408 0.0354465495250363 0.267200660421258 GO:0004707 MAP kinase activity 4/1510 16/18639 0.25 3.08592715231788 0.0355037978471732 0.267200660421258 GO:0005159 insulin-like growth factor receptor binding 4/1510 16/18639 0.25 3.08592715231788 0.0355037978471732 0.267200660421258 GO:0016675 oxidoreductase activity, acting on a heme group of donors 4/1510 16/18639 0.25 3.08592715231788 0.0355037978471732 0.267200660421258 GO:0016722 oxidoreductase activity, acting on metal ions 4/1510 16/18639 0.25 3.08592715231788 0.0355037978471732 0.267200660421258 GO:0034450 ubiquitin-ubiquitin ligase activity 4/1510 16/18639 0.25 3.08592715231788 0.0355037978471732 0.267200660421258 GO:0032266 phosphatidylinositol-3-phosphate binding 8/1510 48/18639 0.166666666666667 2.05728476821192 0.0375378874145144 0.280321255236558 GO:0180051 translation factor activity 12/1510 84/18639 0.142857142857143 1.76338694418165 0.0377309023441786 0.280321255236558 GO:0019003 GDP binding 11/1510 75/18639 0.146666666666667 1.81041059602649 0.0384966438393408 0.281870007309407 GO:0050997 quaternary ammonium group binding 7/1510 40/18639 0.175 2.16014900662252 0.0397249401441252 0.281870007309407 GO:0042625 ATPase-coupled ion transmembrane transporter activity 5/1510 24/18639 0.208333333333333 2.5716059602649 0.0403033434655765 0.281870007309407 GO:0043998 histone H2A acetyltransferase activity 5/1510 24/18639 0.208333333333333 2.5716059602649 0.0403033434655765 0.281870007309407 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 5/1510 24/18639 0.208333333333333 2.5716059602649 0.0403033434655765 0.281870007309407 GO:0046961 proton-transporting ATPase activity, rotational mechanism 5/1510 24/18639 0.208333333333333 2.5716059602649 0.0403033434655765 0.281870007309407 GO:0019207 kinase regulator activity 32/1510 287/18639 0.111498257839721 1.37630200521494 0.0406668038993782 0.281870007309407 GO:0003774 cytoskeletal motor activity 19/1510 153/18639 0.124183006535948 1.532878846903 0.0407763223454275 0.281870007309407 GO:0061775 cohesin loader activity 19/1510 153/18639 0.124183006535948 1.532878846903 0.0407763223454275 0.281870007309407 GO:0004862 cAMP-dependent protein kinase inhibitor activity 3/1510 10/18639 0.3 3.70311258278146 0.0413441770859354 0.281870007309407 GO:0015924 mannosyl-oligosaccharide mannosidase activity 3/1510 10/18639 0.3 3.70311258278146 0.0413441770859354 0.281870007309407 GO:0030957 Tat protein binding 3/1510 10/18639 0.3 3.70311258278146 0.0413441770859354 0.281870007309407 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 3/1510 10/18639 0.3 3.70311258278146 0.0413441770859354 0.281870007309407 GO:0099122 RNA polymerase II C-terminal domain binding 3/1510 10/18639 0.3 3.70311258278146 0.0413441770859354 0.281870007309407 GO:0008237 metallopeptidase activity 22/1510 184/18639 0.119565217391304 1.47587820328246 0.0423550044219109 0.287072807748507 GO:1990226 histone methyltransferase binding 4/1510 17/18639 0.235294117647059 2.90440202571095 0.0435370656648931 0.293368948288436 GO:0033218 amide binding 28/1510 247/18639 0.11336032388664 1.39928680590932 0.0443101511925297 0.295240853930168 GO:0042287 MHC protein binding 7/1510 41/18639 0.170731707317073 2.10746244548538 0.0446838529848485 0.295240853930168 GO:0001221 transcription coregulator binding 15/1510 115/18639 0.130434782608696 1.61004894903542 0.0447149589688877 0.295240853930168 GO:0003712 transcription coregulator activity 51/1510 495/18639 0.103030303030303 1.27177603853101 0.0448338138841324 0.295240853930168 GO:0003724 RNA helicase activity 11/1510 77/18639 0.142857142857143 1.76338694418165 0.0454009639607494 0.297286538025472 GO:0005006 epidermal growth factor receptor activity 8/1510 50/18639 0.16 1.97499337748344 0.0463726625718264 0.301830173758763 GO:0070063 RNA polymerase binding 9/1510 59/18639 0.152542372881356 1.8829386014143 0.0467807520155104 0.301830173758763 GO:0019706 protein-cysteine S-palmitoyltransferase activity 5/1510 25/18639 0.2 2.4687417218543 0.0471365500002899 0.301830173758763 GO:0019707 protein-cysteine S-acyltransferase activity 5/1510 25/18639 0.2 2.4687417218543 0.0471365500002899 0.301830173758763 GO:0003779 actin binding 46/1510 443/18639 0.103837471783296 1.28173949441646 0.0488946853931401 0.310599578901398 GO:0019199 transmembrane receptor protein kinase activity 11/1510 78/18639 0.141025641025641 1.74077941925624 0.0491516700052783 0.310599578901398 GO:0004402 histone acetyltransferase activity 7/1510 42/18639 0.166666666666667 2.05728476821192 0.0500234090285071 0.310599578901398 GO:0019894 kinesin binding 7/1510 42/18639 0.166666666666667 2.05728476821192 0.0500234090285071 0.310599578901398 GO:0051879 Hsp90 protein binding 7/1510 42/18639 0.166666666666667 2.05728476821192 0.0500234090285071 0.310599578901398 GO:0019888 protein phosphatase regulator activity 14/1510 107/18639 0.130841121495327 1.61506467784861 0.0501139959055751 0.310599578901398 GO:0001098 basal transcription machinery binding 9/1510 60/18639 0.15 1.85155629139073 0.0512494387612068 0.311635262211095 GO:0001099 basal RNA polymerase II transcription machinery binding 9/1510 60/18639 0.15 1.85155629139073 0.0512494387612068 0.311635262211095 GO:0070628 proteasome binding 4/1510 18/18639 0.222222222222222 2.74304635761589 0.0525028664974629 0.311635262211095 GO:0098641 cadherin binding involved in cell-cell adhesion 4/1510 18/18639 0.222222222222222 2.74304635761589 0.0525028664974629 0.311635262211095 GO:0008186 ATP-dependent activity, acting on RNA 11/1510 79/18639 0.139240506329114 1.71874423673401 0.0531064951363063 0.311635262211095 GO:0046332 SMAD binding 11/1510 79/18639 0.139240506329114 1.71874423673401 0.0531064951363063 0.311635262211095 GO:0005114 type II transforming growth factor beta receptor binding 3/1510 11/18639 0.272727272727273 3.36646598434678 0.0535076938567799 0.311635262211095 GO:0008199 ferric iron binding 3/1510 11/18639 0.272727272727273 3.36646598434678 0.0535076938567799 0.311635262211095 GO:0008526 phosphatidylinositol transfer activity 3/1510 11/18639 0.272727272727273 3.36646598434678 0.0535076938567799 0.311635262211095 GO:0019864 IgG binding 3/1510 11/18639 0.272727272727273 3.36646598434678 0.0535076938567799 0.311635262211095 GO:0050998 nitric-oxide synthase binding 3/1510 11/18639 0.272727272727273 3.36646598434678 0.0535076938567799 0.311635262211095 GO:0097493 structural molecule activity conferring elasticity 3/1510 11/18639 0.272727272727273 3.36646598434678 0.0535076938567799 0.311635262211095 GO:0005160 transforming growth factor beta receptor binding 5/1510 26/18639 0.192307692307692 2.3737901171676 0.0546135981643966 0.314911245136993 GO:0008198 ferrous iron binding 5/1510 26/18639 0.192307692307692 2.3737901171676 0.0546135981643966 0.314911245136993 GO:0004712 protein serine/threonine/tyrosine kinase activity 7/1510 43/18639 0.162790697674419 2.00944093639304 0.0557494275357225 0.318094637601418 GO:0048156 tau protein binding 7/1510 43/18639 0.162790697674419 2.00944093639304 0.0557494275357225 0.318094637601418 GO:0019905 syntaxin binding 9/1510 61/18639 0.147540983606557 1.82120290956465 0.0559890475156939 0.318094637601418 GO:0005126 cytokine receptor binding 30/1510 275/18639 0.109090909090909 1.34658639373871 0.0584844909111023 0.329046237698872 GO:1901681 sulfur compound binding 30/1510 275/18639 0.109090909090909 1.34658639373871 0.0584844909111023 0.329046237698872 GO:0003689 DNA clamp loader activity 19/1510 160/18639 0.11875 1.46581539735099 0.0593274338271453 0.33217630823991 GO:0010485 histone H4 acetyltransferase activity 6/1510 35/18639 0.171428571428571 2.11606433301798 0.0598590235209227 0.333541385868988 GO:0004713 protein tyrosine kinase activity 17/1510 140/18639 0.121428571428571 1.4988789025544 0.0604852558996962 0.335418237261952 GO:0019887 protein kinase regulator activity 28/1510 255/18639 0.109803921568627 1.35538761199844 0.0615713549739079 0.337441107766881 GO:0004866 endopeptidase inhibitor activity 19/1510 161/18639 0.118012422360248 1.45671095388919 0.0623896115006914 0.337441107766881 GO:0005044 scavenger receptor activity 5/1510 27/18639 0.185185185185185 2.28587196467991 0.062735611712552 0.337441107766881 GO:0005385 zinc ion transmembrane transporter activity 5/1510 27/18639 0.185185185185185 2.28587196467991 0.062735611712552 0.337441107766881 GO:0000510 H3-H4 histone complex chaperone activity 18/1510 151/18639 0.119205298013245 1.47143546335687 0.0631792238010468 0.337441107766881 GO:0140584 chromatin extrusion motor activity 18/1510 151/18639 0.119205298013245 1.47143546335687 0.0631792238010468 0.337441107766881 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 18/1510 151/18639 0.119205298013245 1.47143546335687 0.0631792238010468 0.337441107766881 GO:0140849 ATP-dependent H2AZ histone chaperone activity 18/1510 151/18639 0.119205298013245 1.47143546335687 0.0631792238010468 0.337441107766881 GO:0061630 ubiquitin protein ligase activity 37/1510 353/18639 0.104815864022663 1.29381648312478 0.0637521093916788 0.338938966903467 GO:0008201 heparin binding 20/1510 172/18639 0.116279069767442 1.43531495456646 0.0645226516015702 0.341469192722465 GO:0015616 DNA translocase activity 18/1510 152/18639 0.118421052631579 1.46175496688742 0.0664918254599777 0.347552625886585 GO:0140674 ATP-dependent histone chaperone activity 18/1510 152/18639 0.118421052631579 1.46175496688742 0.0664918254599777 0.347552625886585 GO:0016409 palmitoyltransferase activity 6/1510 36/18639 0.166666666666667 2.05728476821192 0.0671256528948582 0.347552625886585 GO:0008603 cAMP-dependent protein kinase regulator activity 3/1510 12/18639 0.25 3.08592715231788 0.0671715169961993 0.347552625886585 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3/1510 12/18639 0.25 3.08592715231788 0.0671715169961993 0.347552625886585 GO:0003925 G protein activity 8/1510 54/18639 0.148148148148148 1.82869757174393 0.0678515191059646 0.349510713972502 GO:0008238 exopeptidase activity 13/1510 102/18639 0.127450980392157 1.57321776392676 0.0682226715602909 0.349867594417598 GO:0030246 carbohydrate binding 30/1510 280/18639 0.107142857142857 1.32254020813623 0.0704411691807336 0.359653370398548 GO:0097718 disordered domain specific binding 5/1510 28/18639 0.178571428571429 2.20423368022706 0.0714991693886281 0.36345411105886 GO:0140713 histone chaperone activity 19/1510 164/18639 0.115853658536585 1.43006380229365 0.0722243731980911 0.365537329854094 GO:0042288 MHC class I protein binding 4/1510 20/18639 0.2 2.4687417218543 0.0731848682486698 0.368788096957427 GO:0048029 monosaccharide binding 10/1510 74/18639 0.135135135135135 1.66806873098264 0.0744712909846487 0.37295102538114 GO:0140097 catalytic activity, acting on DNA 35/1510 336/18639 0.104166666666667 1.28580298013245 0.0746545624576571 0.37295102538114 GO:0030291 protein serine/threonine kinase inhibitor activity 7/1510 46/18639 0.152173913043478 1.87839044054132 0.075280597691342 0.37432650807966 GO:0051087 protein-folding chaperone binding 16/1510 134/18639 0.119402985074627 1.47387565483839 0.0755758437365318 0.37432650807966 GO:0004386 helicase activity 18/1510 155/18639 0.116129032258065 1.43346293527024 0.0771308498847223 0.380402787303801 GO:0031267 small GTPase binding 30/1510 283/18639 0.106007067137809 1.3085203472726 0.0783838700779338 0.384944514492904 GO:0016417 S-acyltransferase activity 5/1510 29/18639 0.172413793103448 2.12822562228819 0.0808965322676486 0.392254984739636 GO:0043236 laminin binding 5/1510 29/18639 0.172413793103448 2.12822562228819 0.0808965322676486 0.392254984739636 GO:0051861 glycolipid binding 5/1510 29/18639 0.172413793103448 2.12822562228819 0.0808965322676486 0.392254984739636 GO:0004857 enzyme inhibitor activity 42/1510 416/18639 0.100961538461538 1.24623981151299 0.0813439651276937 0.392254984739636 GO:0061659 ubiquitin-like protein ligase activity 38/1510 372/18639 0.102150537634409 1.26091647083956 0.0820651170626156 0.392254984739636 GO:0008035 high-density lipoprotein particle binding 3/1510 13/18639 0.230769230769231 2.84854814060112 0.0822415541775078 0.392254984739636 GO:0140410 monoatomic cation:bicarbonate symporter activity 3/1510 13/18639 0.230769230769231 2.84854814060112 0.0822415541775078 0.392254984739636 GO:0043531 ADP binding 6/1510 38/18639 0.157894736842105 1.94900662251656 0.0831253362352074 0.394845347117235 GO:0019200 carbohydrate kinase activity 4/1510 21/18639 0.19047619047619 2.35118259224219 0.0848556669554509 0.399787471550275 GO:1904047 S-adenosyl-L-methionine binding 4/1510 21/18639 0.19047619047619 2.35118259224219 0.0848556669554509 0.399787471550275 GO:0051536 iron-sulfur cluster binding 10/1510 76/18639 0.131578947368421 1.62417218543046 0.0857869429659663 0.402538732378765 GO:0000149 SNARE binding 13/1510 106/18639 0.122641509433962 1.51385105585405 0.0866666800356295 0.405026944198769 GO:0004601 peroxidase activity 8/1510 57/18639 0.140350877192982 1.73245033112583 0.0873934151808792 0.406783004797747 GO:0003924 GTPase activity 34/1510 331/18639 0.102719033232628 1.26793381484964 0.0902628458709852 0.416818574914883 GO:0140693 molecular condensate scaffold activity 7/1510 48/18639 0.145833333333333 1.80012417218543 0.0902687336528348 0.416818574914883 GO:0030414 peptidase inhibitor activity 19/1510 169/18639 0.112426035502959 1.38775422234414 0.0908360220587931 0.417773609389449 GO:0051540 metal cluster binding 10/1510 77/18639 0.12987012987013 1.60307904016513 0.0918147010264467 0.418643603445052 GO:0005496 steroid binding 13/1510 108/18639 0.12037037037037 1.48581677704194 0.0969556103770485 0.418643603445052 GO:0140223 general transcription initiation factor activity 9/1510 68/18639 0.132352941176471 1.63372613946241 0.0969720730207225 0.418643603445052 GO:0030295 protein kinase activator activity 16/1510 139/18639 0.115107913669065 1.42085854495212 0.0971275245022407 0.418643603445052 GO:0042626 ATPase-coupled transmembrane transporter activity 12/1510 98/18639 0.122448979591837 1.51147452358427 0.0978613651779706 0.418643603445052 GO:0005004 GPI-linked ephrin receptor activity 7/1510 49/18639 0.142857142857143 1.76338694418165 0.0983466988019251 0.418643603445052 GO:0005008 hepatocyte growth factor receptor activity 7/1510 49/18639 0.142857142857143 1.76338694418165 0.0983466988019251 0.418643603445052 GO:0005009 insulin receptor activity 7/1510 49/18639 0.142857142857143 1.76338694418165 0.0983466988019251 0.418643603445052 GO:0005011 macrophage colony-stimulating factor receptor activity 7/1510 49/18639 0.142857142857143 1.76338694418165 0.0983466988019251 0.418643603445052 GO:0005018 platelet-derived growth factor alpha-receptor activity 7/1510 49/18639 0.142857142857143 1.76338694418165 0.0983466988019251 0.418643603445052 GO:0005020 stem cell factor receptor activity 7/1510 49/18639 0.142857142857143 1.76338694418165 0.0983466988019251 0.418643603445052 GO:0008288 boss receptor activity 7/1510 49/18639 0.142857142857143 1.76338694418165 0.0983466988019251 0.418643603445052 GO:0036332 placental growth factor receptor activity 7/1510 49/18639 0.142857142857143 1.76338694418165 0.0983466988019251 0.418643603445052 GO:0038062 protein tyrosine kinase collagen receptor activity 7/1510 49/18639 0.142857142857143 1.76338694418165 0.0983466988019251 0.418643603445052 GO:0060175 brain-derived neurotrophic factor receptor activity 7/1510 49/18639 0.142857142857143 1.76338694418165 0.0983466988019251 0.418643603445052 GO:0004065 arylsulfatase activity 3/1510 14/18639 0.214285714285714 2.64508041627247 0.098610615824417 0.418643603445052 GO:0004705 JUN kinase activity 3/1510 14/18639 0.214285714285714 2.64508041627247 0.098610615824417 0.418643603445052 GO:0008494 translation activator activity 3/1510 14/18639 0.214285714285714 2.64508041627247 0.098610615824417 0.418643603445052 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 3/1510 14/18639 0.214285714285714 2.64508041627247 0.098610615824417 0.418643603445052 GO:0019992 diacylglycerol binding 3/1510 14/18639 0.214285714285714 2.64508041627247 0.098610615824417 0.418643603445052 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 3/1510 14/18639 0.214285714285714 2.64508041627247 0.098610615824417 0.418643603445052 GO:0072349 modified amino acid transmembrane transporter activity 5/1510 31/18639 0.161290322580645 1.99092074343089 0.101541748142974 0.4285746025952 GO:0042393 histone binding 26/1510 247/18639 0.105263157894737 1.29933774834437 0.101750572490603 0.4285746025952 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 8/1510 59/18639 0.135593220338983 1.67372320125716 0.102059180600755 0.4285746025952 GO:0005007 fibroblast growth factor receptor activity 7/1510 50/18639 0.14 1.72811920529801 0.106807588420778 0.443691738278431 GO:0005017 platelet-derived growth factor receptor activity 7/1510 50/18639 0.14 1.72811920529801 0.106807588420778 0.443691738278431 GO:0005019 platelet-derived growth factor beta-receptor activity 7/1510 50/18639 0.14 1.72811920529801 0.106807588420778 0.443691738278431 GO:0004714 transmembrane receptor protein tyrosine kinase activity 8/1510 60/18639 0.133333333333333 1.64582781456954 0.109876063960686 0.45480842189441 GO:0001530 lipopolysaccharide binding 6/1510 41/18639 0.146341463414634 1.80639638184461 0.110711155710888 0.455014998116734 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 6/1510 41/18639 0.146341463414634 1.80639638184461 0.110711155710888 0.455014998116734 GO:0016755 aminoacyltransferase activity 48/1510 496/18639 0.0967741935483871 1.19455244605853 0.112879081134267 0.462285706836099 GO:0005010 insulin-like growth factor receptor activity 7/1510 51/18639 0.137254901960784 1.69423451499805 0.1156448504396 0.462654655432301 GO:0005021 vascular endothelial growth factor receptor activity 7/1510 51/18639 0.137254901960784 1.69423451499805 0.1156448504396 0.462654655432301 GO:0005030 neurotrophin receptor activity 7/1510 51/18639 0.137254901960784 1.69423451499805 0.1156448504396 0.462654655432301 GO:0004559 alpha-mannosidase activity 3/1510 15/18639 0.2 2.4687417218543 0.116162644288869 0.462654655432301 GO:0016846 carbon-sulfur lyase activity 3/1510 15/18639 0.2 2.4687417218543 0.116162644288869 0.462654655432301 GO:0050780 dopamine receptor binding 3/1510 15/18639 0.2 2.4687417218543 0.116162644288869 0.462654655432301 GO:0120283 protein serine/threonine kinase binding 3/1510 15/18639 0.2 2.4687417218543 0.116162644288869 0.462654655432301 GO:0140161 monocarboxylate:sodium symporter activity 3/1510 15/18639 0.2 2.4687417218543 0.116162644288869 0.462654655432301 GO:0015026 coreceptor activity 8/1510 61/18639 0.131147540983607 1.61884703072413 0.118009953235401 0.466653814498799 GO:0016836 hydro-lyase activity 8/1510 61/18639 0.131147540983607 1.61884703072413 0.118009953235401 0.466653814498799 GO:0001618 virus receptor activity 10/1510 81/18639 0.123456790123457 1.52391464311994 0.118374651822819 0.466653814498799 GO:0008307 structural constituent of muscle 6/1510 42/18639 0.142857142857143 1.76338694418165 0.120825780157951 0.469923084574045 GO:0035198 miRNA binding 6/1510 42/18639 0.142857142857143 1.76338694418165 0.120825780157951 0.469923084574045 GO:0043175 RNA polymerase core enzyme binding 6/1510 42/18639 0.142857142857143 1.76338694418165 0.120825780157951 0.469923084574045 GO:0048487 beta-tubulin binding 6/1510 42/18639 0.142857142857143 1.76338694418165 0.120825780157951 0.469923084574045 GO:0140311 protein sequestering activity 5/1510 33/18639 0.151515151515152 1.87025888019265 0.124533727284145 0.482011053369638 GO:0070300 phosphatidic acid binding 4/1510 24/18639 0.166666666666667 2.05728476821192 0.124765587584893 0.482011053369638 GO:0140272 exogenous protein binding 10/1510 82/18639 0.121951219512195 1.50533031820384 0.125617370598035 0.483689476821006 GO:0008094 ATP-dependent activity, acting on DNA 22/1510 210/18639 0.104761904761905 1.29315042573321 0.1284430082942 0.492762283566652 GO:0019787 ubiquitin-like protein transferase activity 46/1510 479/18639 0.0960334029227557 1.18540834243526 0.129126711983348 0.492762283566652 GO:0019001 guanyl nucleotide binding 39/1510 400/18639 0.0975 1.20351158940397 0.130562199947086 0.492762283566652 GO:0032561 guanyl ribonucleotide binding 39/1510 400/18639 0.0975 1.20351158940397 0.130562199947086 0.492762283566652 GO:0051219 phosphoprotein binding 11/1510 93/18639 0.118279569892473 1.46000854518265 0.131003129988593 0.492762283566652 GO:0008200 ion channel inhibitor activity 6/1510 43/18639 0.13953488372093 1.72237794547975 0.131378702204799 0.492762283566652 GO:0008375 acetylglucosaminyltransferase activity 6/1510 43/18639 0.13953488372093 1.72237794547975 0.131378702204799 0.492762283566652 GO:0005003 ephrin receptor activity 7/1510 53/18639 0.132075471698113 1.6303011370736 0.134415536712552 0.492762283566652 GO:0005005 transmembrane-ephrin receptor activity 7/1510 53/18639 0.132075471698113 1.6303011370736 0.134415536712552 0.492762283566652 GO:0016251 RNA polymerase II general transcription initiation factor activity 7/1510 53/18639 0.132075471698113 1.6303011370736 0.134415536712552 0.492762283566652 GO:0038064 collagen receptor activity 7/1510 53/18639 0.132075471698113 1.6303011370736 0.134415536712552 0.492762283566652 GO:0005024 transforming growth factor beta receptor activity 3/1510 16/18639 0.1875 2.31444536423841 0.134776224236953 0.492762283566652 GO:0005521 lamin binding 3/1510 16/18639 0.1875 2.31444536423841 0.134776224236953 0.492762283566652 GO:0015923 mannosidase activity 3/1510 16/18639 0.1875 2.31444536423841 0.134776224236953 0.492762283566652 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/1510 16/18639 0.1875 2.31444536423841 0.134776224236953 0.492762283566652 GO:0055102 lipase inhibitor activity 3/1510 16/18639 0.1875 2.31444536423841 0.134776224236953 0.492762283566652 GO:0005507 copper ion binding 8/1510 63/18639 0.126984126984127 1.5674550614948 0.135205934452709 0.492778861731729 GO:0101005 deubiquitinase activity 13/1510 115/18639 0.11304347826087 1.39537575583069 0.138551624770421 0.503389758962126 GO:0004709 MAP kinase kinase kinase activity 4/1510 25/18639 0.16 1.97499337748344 0.139552070934342 0.503865576987234 GO:0008139 nuclear localization sequence binding 4/1510 25/18639 0.16 1.97499337748344 0.139552070934342 0.503865576987234 GO:0004842 ubiquitin-protein transferase activity 43/1510 449/18639 0.0957683741648107 1.18213690467411 0.142310707776572 0.510800973079557 GO:0016248 channel inhibitor activity 6/1510 44/18639 0.136363636363636 1.68323299217339 0.142354369546762 0.510800973079557 GO:0031491 nucleosome binding 9/1510 74/18639 0.121621621621622 1.50126185788437 0.142925073002036 0.511265924720245 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 7/1510 54/18639 0.12962962962963 1.60011037527594 0.144329326568852 0.51434367027176 GO:0019209 kinase activator activity 16/1510 148/18639 0.108108108108108 1.33445498478611 0.144673025460392 0.51434367027176 GO:0000175 3'-5'-RNA exonuclease activity 5/1510 35/18639 0.142857142857143 1.76338694418165 0.14968518489813 0.526802647886604 GO:0003714 transcription corepressor activity 21/1510 204/18639 0.102941176470588 1.27067588624854 0.152588558823346 0.526802647886604 GO:0141110 transporter inhibitor activity 6/1510 45/18639 0.133333333333333 1.64582781456954 0.153735628285774 0.526802647886604 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/1510 17/18639 0.176470588235294 2.17830151928321 0.154327472502394 0.526802647886604 GO:0008429 phosphatidylethanolamine binding 3/1510 17/18639 0.176470588235294 2.17830151928321 0.154327472502394 0.526802647886604 GO:0008484 sulfuric ester hydrolase activity 3/1510 17/18639 0.176470588235294 2.17830151928321 0.154327472502394 0.526802647886604 GO:0019198 transmembrane receptor protein phosphatase activity 3/1510 17/18639 0.176470588235294 2.17830151928321 0.154327472502394 0.526802647886604 GO:0032183 SUMO binding 3/1510 17/18639 0.176470588235294 2.17830151928321 0.154327472502394 0.526802647886604 GO:0051787 misfolded protein binding 3/1510 17/18639 0.176470588235294 2.17830151928321 0.154327472502394 0.526802647886604 GO:0070402 NADPH binding 3/1510 17/18639 0.176470588235294 2.17830151928321 0.154327472502394 0.526802647886604 GO:0070492 oligosaccharide binding 3/1510 17/18639 0.176470588235294 2.17830151928321 0.154327472502394 0.526802647886604 GO:0019865 immunoglobulin binding 4/1510 26/18639 0.153846153846154 1.89903209373408 0.154995429619786 0.526802647886604 GO:0030247 polysaccharide binding 4/1510 26/18639 0.153846153846154 1.89903209373408 0.154995429619786 0.526802647886604 GO:0050681 nuclear androgen receptor binding 4/1510 26/18639 0.153846153846154 1.89903209373408 0.154995429619786 0.526802647886604 GO:0070412 R-SMAD binding 4/1510 26/18639 0.153846153846154 1.89903209373408 0.154995429619786 0.526802647886604 GO:0019842 vitamin binding 16/1510 150/18639 0.106666666666667 1.31666225165563 0.156733742967541 0.531153240056665 GO:0035591 signaling adaptor activity 14/1510 129/18639 0.108527131782946 1.33962729092869 0.160788328046408 0.54330516678072 GO:0000993 RNA polymerase II complex binding 5/1510 36/18639 0.138888888888889 1.71440397350993 0.163001238447045 0.547589667710507 GO:0005484 SNAP receptor activity 5/1510 36/18639 0.138888888888889 1.71440397350993 0.163001238447045 0.547589667710507 GO:0005516 calmodulin binding 21/1510 207/18639 0.101449275362319 1.25226029369421 0.168512257852375 0.56446736084076 GO:0004197 cysteine-type endopeptidase activity 10/1510 88/18639 0.113636363636364 1.40269416014449 0.173862981849876 0.573678181930884 GO:0031072 heat shock protein binding 14/1510 131/18639 0.106870229007634 1.31917496587635 0.174631514575861 0.573678181930884 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 3/1510 18/18639 0.166666666666667 2.05728476821192 0.174692393703381 0.573678181930884 GO:0008525 phosphatidylcholine transporter activity 3/1510 18/18639 0.166666666666667 2.05728476821192 0.174692393703381 0.573678181930884 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 3/1510 18/18639 0.166666666666667 2.05728476821192 0.174692393703381 0.573678181930884 GO:0070064 proline-rich region binding 3/1510 18/18639 0.166666666666667 2.05728476821192 0.174692393703381 0.573678181930884 GO:0016758 hexosyltransferase activity 20/1510 197/18639 0.101522842639594 1.25316838672807 0.174726831942711 0.573678181930884 GO:0005525 GTP binding 36/1510 378/18639 0.0952380952380952 1.1755912961211 0.175406257892549 0.57428207033182 GO:0070279 vitamin B6 binding 7/1510 57/18639 0.12280701754386 1.5158940397351 0.176042849071604 0.574742710067576 GO:0004540 RNA nuclease activity 13/1510 121/18639 0.107438016528926 1.32618356959116 0.180822092324432 0.576807364139016 GO:0003777 microtubule motor activity 8/1510 68/18639 0.117647058823529 1.45220101285547 0.183251620595859 0.576807364139016 GO:0061980 regulatory RNA binding 7/1510 58/18639 0.120689655172414 1.48975793560174 0.187226247901526 0.576807364139016 GO:0019789 SUMO transferase activity 4/1510 28/18639 0.142857142857143 1.76338694418165 0.187630856335143 0.576807364139016 GO:0046625 sphingolipid binding 4/1510 28/18639 0.142857142857143 1.76338694418165 0.187630856335143 0.576807364139016 GO:0046966 nuclear thyroid hormone receptor binding 4/1510 28/18639 0.142857142857143 1.76338694418165 0.187630856335143 0.576807364139016 GO:0051019 mitogen-activated protein kinase binding 4/1510 28/18639 0.142857142857143 1.76338694418165 0.187630856335143 0.576807364139016 GO:0051393 alpha-actinin binding 4/1510 28/18639 0.142857142857143 1.76338694418165 0.187630856335143 0.576807364139016 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 13/1510 122/18639 0.10655737704918 1.31531321246336 0.188417572832191 0.576807364139016 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 6/1510 48/18639 0.125 1.54296357615894 0.190120761636038 0.576807364139016 GO:0000146 microfilament motor activity 5/1510 38/18639 0.131578947368421 1.62417218543046 0.190958421252769 0.576807364139016 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 5/1510 38/18639 0.131578947368421 1.62417218543046 0.190958421252769 0.576807364139016 GO:0042162 telomeric DNA binding 5/1510 38/18639 0.131578947368421 1.62417218543046 0.190958421252769 0.576807364139016 GO:0000182 rDNA binding 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0001094 TFIID-class transcription factor complex binding 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0004955 prostaglandin receptor activity 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0005381 iron ion transmembrane transporter activity 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0008239 dipeptidyl-peptidase activity 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0015187 glycine transmembrane transporter activity 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0031434 mitogen-activated protein kinase kinase binding 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0035374 chondroitin sulfate binding 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0043208 glycosphingolipid binding 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0050815 phosphoserine residue binding 2/1510 10/18639 0.2 2.4687417218543 0.191605552367145 0.576807364139016 GO:0005200 structural constituent of cytoskeleton 12/1510 112/18639 0.107142857142857 1.32254020813623 0.195364497395332 0.58172521256583 GO:0008574 plus-end-directed microtubule motor activity 3/1510 19/18639 0.157894736842105 1.94900662251656 0.195748777308606 0.58172521256583 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 3/1510 19/18639 0.157894736842105 1.94900662251656 0.195748777308606 0.58172521256583 GO:0043395 heparan sulfate proteoglycan binding 3/1510 19/18639 0.157894736842105 1.94900662251656 0.195748777308606 0.58172521256583 GO:0097001 ceramide binding 3/1510 19/18639 0.157894736842105 1.94900662251656 0.195748777308606 0.58172521256583 GO:0008194 UDP-glycosyltransferase activity 15/1510 145/18639 0.103448275862069 1.27693537337292 0.196368907085488 0.582075609493811 GO:0000049 tRNA binding 9/1510 80/18639 0.1125 1.38866721854305 0.197972179415072 0.585331010056296 GO:0045309 protein phosphorylated amino acid binding 7/1510 59/18639 0.11864406779661 1.46450780110001 0.198691045422784 0.585961632684495 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 4/1510 29/18639 0.137931034482759 1.70258049783055 0.204708348185941 0.602175064841386 GO:0016779 nucleotidyltransferase activity 14/1510 136/18639 0.102941176470588 1.27067588624854 0.211681496334461 0.614889512799978 GO:0140789 histone phosphatase activity 14/1510 136/18639 0.102941176470588 1.27067588624854 0.211681496334461 0.614889512799978 GO:0016741 transferase activity, transferring one-carbon groups 21/1510 215/18639 0.0976744186046512 1.20566456183582 0.215040070720749 0.614889512799978 GO:0008168 methyltransferase activity 20/1510 204/18639 0.0980392156862745 1.21016751071289 0.217065485875128 0.614889512799978 GO:0016408 C-acyltransferase activity 3/1510 20/18639 0.15 1.85155629139073 0.217377702436829 0.614889512799978 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 3/1510 20/18639 0.15 1.85155629139073 0.217377702436829 0.614889512799978 GO:0030742 GTP-dependent protein binding 3/1510 20/18639 0.15 1.85155629139073 0.217377702436829 0.614889512799978 GO:0031418 L-ascorbic acid binding 3/1510 20/18639 0.15 1.85155629139073 0.217377702436829 0.614889512799978 GO:0004532 RNA exonuclease activity 5/1510 40/18639 0.125 1.54296357615894 0.220459543633966 0.614889512799978 GO:0030331 nuclear estrogen receptor binding 5/1510 40/18639 0.125 1.54296357615894 0.220459543633966 0.614889512799978 GO:0035401 histone H3Y41 kinase activity 12/1510 115/18639 0.104347826086957 1.28803915922833 0.220610285770006 0.614889512799978 GO:0140801 histone H2AXY142 kinase activity 12/1510 115/18639 0.104347826086957 1.28803915922833 0.220610285770006 0.614889512799978 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 2/1510 11/18639 0.181818181818182 2.24431065623119 0.222293965369448 0.614889512799978 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 2/1510 11/18639 0.181818181818182 2.24431065623119 0.222293965369448 0.614889512799978 GO:0003953 NAD+ nucleosidase activity 2/1510 11/18639 0.181818181818182 2.24431065623119 0.222293965369448 0.614889512799978 GO:0004954 prostanoid receptor activity 2/1510 11/18639 0.181818181818182 2.24431065623119 0.222293965369448 0.614889512799978 GO:0008172 S-methyltransferase activity 2/1510 11/18639 0.181818181818182 2.24431065623119 0.222293965369448 0.614889512799978 GO:0008432 JUN kinase binding 2/1510 11/18639 0.181818181818182 2.24431065623119 0.222293965369448 0.614889512799978 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/1510 11/18639 0.181818181818182 2.24431065623119 0.222293965369448 0.614889512799978 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 2/1510 11/18639 0.181818181818182 2.24431065623119 0.222293965369448 0.614889512799978 GO:0019206 nucleoside kinase activity 2/1510 11/18639 0.181818181818182 2.24431065623119 0.222293965369448 0.614889512799978 GO:0032794 GTPase activating protein binding 2/1510 11/18639 0.181818181818182 2.24431065623119 0.222293965369448 0.614889512799978 GO:0034713 type I transforming growth factor beta receptor binding 2/1510 11/18639 0.181818181818182 2.24431065623119 0.222293965369448 0.614889512799978 GO:0042608 T cell receptor binding 2/1510 11/18639 0.181818181818182 2.24431065623119 0.222293965369448 0.614889512799978 GO:0050786 RAGE receptor binding 2/1510 11/18639 0.181818181818182 2.24431065623119 0.222293965369448 0.614889512799978 GO:0019783 ubiquitin-like protein peptidase activity 13/1510 127/18639 0.102362204724409 1.26352922772071 0.228521865400232 0.630611528568735 GO:0042562 hormone binding 10/1510 94/18639 0.106382978723404 1.31316049034803 0.229439165049119 0.631638936560402 GO:0042169 SH2 domain binding 5/1510 41/18639 0.121951219512195 1.50533031820384 0.235702375289948 0.645813363974114 GO:0061650 ubiquitin-like protein conjugating enzyme activity 5/1510 41/18639 0.121951219512195 1.50533031820384 0.235702375289948 0.645813363974114 GO:1990782 protein tyrosine kinase binding 12/1510 117/18639 0.102564102564103 1.26602139582272 0.238149701988679 0.64694544750141 GO:0004527 exonuclease activity 9/1510 84/18639 0.107142857142857 1.32254020813623 0.238915472394036 0.64694544750141 GO:0009931 calcium-dependent protein serine/threonine kinase activity 3/1510 21/18639 0.142857142857143 1.76338694418165 0.239464708350393 0.64694544750141 GO:0010314 phosphatidylinositol-5-phosphate binding 3/1510 21/18639 0.142857142857143 1.76338694418165 0.239464708350393 0.64694544750141 GO:0036122 BMP binding 3/1510 21/18639 0.142857142857143 1.76338694418165 0.239464708350393 0.64694544750141 GO:0070182 DNA polymerase binding 3/1510 21/18639 0.142857142857143 1.76338694418165 0.239464708350393 0.64694544750141 GO:0005164 tumor necrosis factor receptor binding 4/1510 31/18639 0.129032258064516 1.59273659474471 0.240092377965064 0.647132711770951 GO:0016887 ATP hydrolysis activity 38/1510 417/18639 0.0911270983213429 1.12484634808709 0.245715096023997 0.655033891090093 GO:1901682 sulfur compound transmembrane transporter activity 7/1510 63/18639 0.111111111111111 1.37152317880795 0.247037516587426 0.655033891090093 GO:0004518 nuclease activity 20/1510 209/18639 0.0956937799043062 1.18121613485852 0.249915686760416 0.655033891090093 GO:0051015 actin filament binding 20/1510 209/18639 0.0956937799043062 1.18121613485852 0.249915686760416 0.655033891090093 GO:0004520 DNA endonuclease activity 5/1510 42/18639 0.119047619047619 1.46948912015137 0.251226239496975 0.655033891090093 GO:0004721 phosphoprotein phosphatase activity 17/1510 175/18639 0.0971428571428571 1.19910312204352 0.251792462912323 0.655033891090093 GO:0004859 phospholipase inhibitor activity 2/1510 12/18639 0.166666666666667 2.05728476821192 0.253318455044098 0.655033891090093 GO:0005078 MAP-kinase scaffold activity 2/1510 12/18639 0.166666666666667 2.05728476821192 0.253318455044098 0.655033891090093 GO:0005165 neurotrophin receptor binding 2/1510 12/18639 0.166666666666667 2.05728476821192 0.253318455044098 0.655033891090093 GO:0016208 AMP binding 2/1510 12/18639 0.166666666666667 2.05728476821192 0.253318455044098 0.655033891090093 GO:0016423 tRNA (guanine) methyltransferase activity 2/1510 12/18639 0.166666666666667 2.05728476821192 0.253318455044098 0.655033891090093 GO:0070008 serine-type exopeptidase activity 2/1510 12/18639 0.166666666666667 2.05728476821192 0.253318455044098 0.655033891090093 GO:0070679 inositol 1,4,5 trisphosphate binding 2/1510 12/18639 0.166666666666667 2.05728476821192 0.253318455044098 0.655033891090093 GO:0097371 MDM2/MDM4 family protein binding 2/1510 12/18639 0.166666666666667 2.05728476821192 0.253318455044098 0.655033891090093 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 2/1510 12/18639 0.166666666666667 2.05728476821192 0.253318455044098 0.655033891090093 GO:0008234 cysteine-type peptidase activity 18/1510 187/18639 0.0962566844919786 1.18816446506357 0.256133542540238 0.655033891090093 GO:0004864 protein phosphatase inhibitor activity 6/1510 53/18639 0.113207547169811 1.39740097463451 0.256927304178773 0.655033891090093 GO:0017046 peptide hormone binding 6/1510 53/18639 0.113207547169811 1.39740097463451 0.256927304178773 0.655033891090093 GO:0140296 general transcription initiation factor binding 6/1510 53/18639 0.113207547169811 1.39740097463451 0.256927304178773 0.655033891090093 GO:0106310 protein serine kinase activity 33/1510 361/18639 0.0914127423822715 1.12837225514116 0.257993023482839 0.655033891090093 GO:0004843 cysteine-type deubiquitinase activity 11/1510 108/18639 0.101851851851852 1.25722958057395 0.258026604613589 0.655033891090093 GO:0030515 snoRNA binding 4/1510 32/18639 0.125 1.54296357615894 0.25828342383794 0.655033891090093 GO:0042910 xenobiotic transmembrane transporter activity 4/1510 32/18639 0.125 1.54296357615894 0.25828342383794 0.655033891090093 GO:0043425 bHLH transcription factor binding 4/1510 32/18639 0.125 1.54296357615894 0.25828342383794 0.655033891090093 GO:0070717 poly-purine tract binding 4/1510 32/18639 0.125 1.54296357615894 0.25828342383794 0.655033891090093 GO:0071813 lipoprotein particle binding 4/1510 32/18639 0.125 1.54296357615894 0.25828342383794 0.655033891090093 GO:0071814 protein-lipid complex binding 4/1510 32/18639 0.125 1.54296357615894 0.25828342383794 0.655033891090093 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 9/1510 86/18639 0.104651162790698 1.29178345910981 0.260428278962303 0.659031387155697 GO:0070034 telomerase RNA binding 3/1510 22/18639 0.136363636363636 1.68323299217339 0.261900681240031 0.65987584686347 GO:0140035 ubiquitin-like protein reader activity 3/1510 22/18639 0.136363636363636 1.68323299217339 0.261900681240031 0.65987584686347 GO:0017069 snRNA binding 6/1510 54/18639 0.111111111111111 1.37152317880795 0.271002051380013 0.678974256706254 GO:0140463 chromatin-protein adaptor activity 6/1510 54/18639 0.111111111111111 1.37152317880795 0.271002051380013 0.678974256706254 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 13/1510 132/18639 0.0984848484848485 1.21566827212523 0.271735292280326 0.678974256706254 GO:0017022 myosin binding 8/1510 76/18639 0.105263157894737 1.29933774834437 0.272409861405011 0.678974256706254 GO:0098631 cell adhesion mediator activity 8/1510 76/18639 0.105263157894737 1.29933774834437 0.272409861405011 0.678974256706254 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 4/1510 33/18639 0.121212121212121 1.49620710415412 0.27673165784536 0.683482294255235 GO:0004222 metalloendopeptidase activity 11/1510 110/18639 0.1 1.23437086092715 0.277561911313805 0.683482294255235 GO:0030547 signaling receptor inhibitor activity 5/1510 44/18639 0.113636363636364 1.40269416014449 0.282975303933425 0.683482294255235 GO:0004535 poly(A)-specific ribonuclease activity 2/1510 13/18639 0.153846153846154 1.89903209373408 0.284423346110751 0.683482294255235 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/1510 13/18639 0.153846153846154 1.89903209373408 0.284423346110751 0.683482294255235 GO:0005172 vascular endothelial growth factor receptor binding 2/1510 13/18639 0.153846153846154 1.89903209373408 0.284423346110751 0.683482294255235 GO:0005542 folic acid binding 2/1510 13/18639 0.153846153846154 1.89903209373408 0.284423346110751 0.683482294255235 GO:0019855 calcium channel inhibitor activity 2/1510 13/18639 0.153846153846154 1.89903209373408 0.284423346110751 0.683482294255235 GO:0030955 potassium ion binding 2/1510 13/18639 0.153846153846154 1.89903209373408 0.284423346110751 0.683482294255235 GO:0035325 Toll-like receptor binding 2/1510 13/18639 0.153846153846154 1.89903209373408 0.284423346110751 0.683482294255235 GO:0035673 oligopeptide transmembrane transporter activity 2/1510 13/18639 0.153846153846154 1.89903209373408 0.284423346110751 0.683482294255235 GO:0070123 transforming growth factor beta receptor activity, type III 2/1510 13/18639 0.153846153846154 1.89903209373408 0.284423346110751 0.683482294255235 GO:0003887 DNA-directed DNA polymerase activity 3/1510 23/18639 0.130434782608696 1.61004894903542 0.284582501391285 0.683482294255235 GO:0005212 structural constituent of eye lens 3/1510 23/18639 0.130434782608696 1.61004894903542 0.284582501391285 0.683482294255235 GO:0017134 fibroblast growth factor binding 3/1510 23/18639 0.130434782608696 1.61004894903542 0.284582501391285 0.683482294255235 GO:0070577 lysine-acetylated histone binding 3/1510 23/18639 0.130434782608696 1.61004894903542 0.284582501391285 0.683482294255235 GO:0140102 catalytic activity, acting on a rRNA 3/1510 23/18639 0.130434782608696 1.61004894903542 0.284582501391285 0.683482294255235 GO:0098632 cell-cell adhesion mediator activity 6/1510 55/18639 0.109090909090909 1.34658639373871 0.285257766571655 0.683482294255235 GO:0008235 metalloexopeptidase activity 7/1510 66/18639 0.106060606060606 1.30918121613486 0.285423149628588 0.683482294255235 GO:0003727 single-stranded RNA binding 9/1510 89/18639 0.101123595505618 1.24824019644319 0.293754877685612 0.701983305644585 GO:0008376 acetylgalactosaminyltransferase activity 4/1510 34/18639 0.117647058823529 1.45220101285547 0.295382162074081 0.70297315368349 GO:0052866 phosphatidylinositol phosphate phosphatase activity 4/1510 34/18639 0.117647058823529 1.45220101285547 0.295382162074081 0.70297315368349 GO:0016500 protein-hormone receptor activity 7/1510 67/18639 0.104477611940299 1.28964119798359 0.298527390433438 0.70736760593342 GO:0008009 chemokine activity 5/1510 45/18639 0.111111111111111 1.37152317880795 0.299130263389381 0.70736760593342 GO:0019212 phosphatase inhibitor activity 6/1510 56/18639 0.107142857142857 1.32254020813623 0.29966996938163 0.70736760593342 GO:0030170 pyridoxal phosphate binding 6/1510 56/18639 0.107142857142857 1.32254020813623 0.29966996938163 0.70736760593342 GO:0046982 protein heterodimerization activity 33/1510 369/18639 0.0894308943089431 1.10390890001615 0.301026960232106 0.709126518107747 GO:0001091 RNA polymerase II general transcription initiation factor binding 3/1510 24/18639 0.125 1.54296357615894 0.307413489077912 0.714676808515108 GO:0035035 histone acetyltransferase binding 3/1510 24/18639 0.125 1.54296357615894 0.307413489077912 0.714676808515108 GO:0048027 mRNA 5'-UTR binding 3/1510 24/18639 0.125 1.54296357615894 0.307413489077912 0.714676808515108 GO:0050699 WW domain binding 3/1510 24/18639 0.125 1.54296357615894 0.307413489077912 0.714676808515108 GO:0070840 dynein complex binding 3/1510 24/18639 0.125 1.54296357615894 0.307413489077912 0.714676808515108 GO:0140033 acetylation-dependent protein binding 3/1510 24/18639 0.125 1.54296357615894 0.307413489077912 0.714676808515108 GO:0044325 transmembrane transporter binding 13/1510 136/18639 0.0955882352941176 1.17991332294507 0.308095068340698 0.714676808515108 GO:0016835 carbon-oxygen lyase activity 8/1510 79/18639 0.10126582278481 1.24999580853383 0.308618439661922 0.714676808515108 GO:0008017 microtubule binding 25/1510 276/18639 0.0905797101449275 1.11808954794126 0.308932770548808 0.714676808515108 GO:0030145 manganese ion binding 7/1510 68/18639 0.102941176470588 1.27067588624854 0.311755757463979 0.715157897030312 GO:0061631 ubiquitin conjugating enzyme activity 4/1510 35/18639 0.114285714285714 1.41070955534532 0.314181772032267 0.715157897030312 GO:0005161 platelet-derived growth factor receptor binding 2/1510 14/18639 0.142857142857143 1.76338694418165 0.315392134491806 0.715157897030312 GO:0008559 ABC-type xenobiotic transporter activity 2/1510 14/18639 0.142857142857143 1.76338694418165 0.315392134491806 0.715157897030312 GO:0015926 glucosidase activity 2/1510 14/18639 0.142857142857143 1.76338694418165 0.315392134491806 0.715157897030312 GO:0019763 immunoglobulin receptor activity 2/1510 14/18639 0.142857142857143 1.76338694418165 0.315392134491806 0.715157897030312 GO:0032036 myosin heavy chain binding 2/1510 14/18639 0.142857142857143 1.76338694418165 0.315392134491806 0.715157897030312 GO:0046030 inositol trisphosphate phosphatase activity 2/1510 14/18639 0.142857142857143 1.76338694418165 0.315392134491806 0.715157897030312 GO:0070742 C2H2 zinc finger domain binding 2/1510 14/18639 0.142857142857143 1.76338694418165 0.315392134491806 0.715157897030312 GO:0071933 Arp2/3 complex binding 2/1510 14/18639 0.142857142857143 1.76338694418165 0.315392134491806 0.715157897030312 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 9/1510 91/18639 0.0989010989010989 1.22080634597191 0.316545298685548 0.715157897030312 GO:0072341 modified amino acid binding 9/1510 91/18639 0.0989010989010989 1.22080634597191 0.316545298685548 0.715157897030312 GO:0048306 calcium-dependent protein binding 8/1510 80/18639 0.1 1.23437086092715 0.320912468578239 0.723613912611242 GO:0002039 p53 binding 7/1510 69/18639 0.101449275362319 1.25226029369421 0.325090075327294 0.726106964044715 GO:0004674 protein serine/threonine kinase activity 38/1510 433/18639 0.0877598152424942 1.08328158695685 0.326101894682911 0.726106964044715 GO:0008408 3'-5' exonuclease activity 6/1510 58/18639 0.103448275862069 1.27693537337292 0.328866808235627 0.726106964044715 GO:0015645 fatty acid ligase activity 3/1510 25/18639 0.12 1.48124503311258 0.330303682461126 0.726106964044715 GO:0017056 structural constituent of nuclear pore 3/1510 25/18639 0.12 1.48124503311258 0.330303682461126 0.726106964044715 GO:0120515 fatty acid-CoA ligase activity 3/1510 25/18639 0.12 1.48124503311258 0.330303682461126 0.726106964044715 GO:0001784 phosphotyrosine residue binding 5/1510 47/18639 0.106382978723404 1.31316049034803 0.331829366465688 0.726106964044715 GO:0140359 ABC-type transporter activity 5/1510 47/18639 0.106382978723404 1.31316049034803 0.331829366465688 0.726106964044715 GO:0004869 cysteine-type endopeptidase inhibitor activity 4/1510 36/18639 0.111111111111111 1.37152317880795 0.333079338730421 0.726106964044715 GO:0045505 dynein intermediate chain binding 4/1510 36/18639 0.111111111111111 1.37152317880795 0.333079338730421 0.726106964044715 GO:0033192 calmodulin-dependent protein phosphatase activity 8/1510 81/18639 0.0987654320987654 1.21913171449595 0.333294999889377 0.726106964044715 GO:0140791 histone H2AXS140 phosphatase activity 8/1510 81/18639 0.0987654320987654 1.21913171449595 0.333294999889377 0.726106964044715 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 8/1510 81/18639 0.0987654320987654 1.21913171449595 0.333294999889377 0.726106964044715 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 8/1510 81/18639 0.0987654320987654 1.21913171449595 0.333294999889377 0.726106964044715 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 8/1510 81/18639 0.0987654320987654 1.21913171449595 0.333294999889377 0.726106964044715 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 8/1510 81/18639 0.0987654320987654 1.21913171449595 0.333294999889377 0.726106964044715 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 8/1510 81/18639 0.0987654320987654 1.21913171449595 0.333294999889377 0.726106964044715 GO:1990439 MAP kinase serine/threonine phosphatase activity 8/1510 81/18639 0.0987654320987654 1.21913171449595 0.333294999889377 0.726106964044715 GO:0070851 growth factor receptor binding 13/1510 139/18639 0.0935251798561151 1.1544475677736 0.336163313678254 0.730981764639955 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 8/1510 82/18639 0.0975609756097561 1.20426425456308 0.345751864691229 0.734548781160673 GO:0033549 MAP kinase phosphatase activity 8/1510 82/18639 0.0975609756097561 1.20426425456308 0.345751864691229 0.734548781160673 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/1510 15/18639 0.133333333333333 1.64582781456954 0.346042825292258 0.734548781160673 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/1510 15/18639 0.133333333333333 1.64582781456954 0.346042825292258 0.734548781160673 GO:0004953 icosanoid receptor activity 2/1510 15/18639 0.133333333333333 1.64582781456954 0.346042825292258 0.734548781160673 GO:0005041 low-density lipoprotein particle receptor activity 2/1510 15/18639 0.133333333333333 1.64582781456954 0.346042825292258 0.734548781160673 GO:0005523 tropomyosin binding 2/1510 15/18639 0.133333333333333 1.64582781456954 0.346042825292258 0.734548781160673 GO:0015929 hexosaminidase activity 2/1510 15/18639 0.133333333333333 1.64582781456954 0.346042825292258 0.734548781160673 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/1510 15/18639 0.133333333333333 1.64582781456954 0.346042825292258 0.734548781160673 GO:0017081 chloride channel regulator activity 2/1510 15/18639 0.133333333333333 1.64582781456954 0.346042825292258 0.734548781160673 GO:0042809 nuclear vitamin D receptor binding 2/1510 15/18639 0.133333333333333 1.64582781456954 0.346042825292258 0.734548781160673 GO:0045504 dynein heavy chain binding 2/1510 15/18639 0.133333333333333 1.64582781456954 0.346042825292258 0.734548781160673 GO:0061578 K63-linked deubiquitinase activity 2/1510 15/18639 0.133333333333333 1.64582781456954 0.346042825292258 0.734548781160673 GO:0042805 actinin binding 4/1510 37/18639 0.108108108108108 1.33445498478611 0.352025942523845 0.744225459169611 GO:0008143 poly(A) binding 3/1510 26/18639 0.115384615384615 1.42427407030056 0.353169976309996 0.744225459169611 GO:0097602 cullin family protein binding 3/1510 26/18639 0.115384615384615 1.42427407030056 0.353169976309996 0.744225459169611 GO:0120014 phospholipid transfer activity 3/1510 26/18639 0.115384615384615 1.42427407030056 0.353169976309996 0.744225459169611 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 8/1510 83/18639 0.0963855421686747 1.18975504667677 0.358269010058862 0.751152986944157 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 6/1510 60/18639 0.1 1.23437086092715 0.358401727161448 0.751152986944157 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 6/1510 60/18639 0.1 1.23437086092715 0.358401727161448 0.751152986944157 GO:0004867 serine-type endopeptidase inhibitor activity 9/1510 95/18639 0.0947368421052632 1.16940397350993 0.363086068117793 0.754400255120908 GO:0008276 protein methyltransferase activity 9/1510 95/18639 0.0947368421052632 1.16940397350993 0.363086068117793 0.754400255120908 GO:0001222 transcription corepressor binding 5/1510 49/18639 0.102040816326531 1.25956210298689 0.36482764148504 0.754400255120908 GO:0042379 chemokine receptor binding 7/1510 72/18639 0.0972222222222222 1.20008278145695 0.365549385577778 0.754400255120908 GO:0005319 lipid transporter activity 16/1510 178/18639 0.0898876404494382 1.10954684128283 0.36982344294509 0.754400255120908 GO:0004860 protein kinase inhibitor activity 8/1510 84/18639 0.0952380952380952 1.1755912961211 0.37083254033937 0.754400255120908 GO:0017018 myosin phosphatase activity 8/1510 84/18639 0.0952380952380952 1.1755912961211 0.37083254033937 0.754400255120908 GO:0005109 frizzled binding 4/1510 38/18639 0.105263157894737 1.29933774834437 0.370975062673383 0.754400255120908 GO:0005501 retinoid binding 4/1510 38/18639 0.105263157894737 1.29933774834437 0.370975062673383 0.754400255120908 GO:0019840 isoprenoid binding 4/1510 38/18639 0.105263157894737 1.29933774834437 0.370975062673383 0.754400255120908 GO:0042887 amide transmembrane transporter activity 4/1510 38/18639 0.105263157894737 1.29933774834437 0.370975062673383 0.754400255120908 GO:0004364 glutathione transferase activity 3/1510 27/18639 0.111111111111111 1.37152317880795 0.375936146430898 0.754400255120908 GO:0004683 calcium/calmodulin-dependent protein kinase activity 3/1510 27/18639 0.111111111111111 1.37152317880795 0.375936146430898 0.754400255120908 GO:0008266 poly(U) RNA binding 3/1510 27/18639 0.111111111111111 1.37152317880795 0.375936146430898 0.754400255120908 GO:0015252 proton channel activity 3/1510 27/18639 0.111111111111111 1.37152317880795 0.375936146430898 0.754400255120908 GO:0016405 CoA-ligase activity 3/1510 27/18639 0.111111111111111 1.37152317880795 0.375936146430898 0.754400255120908 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/1510 16/18639 0.125 1.54296357615894 0.376223768300159 0.754400255120908 GO:0004708 MAP kinase kinase activity 2/1510 16/18639 0.125 1.54296357615894 0.376223768300159 0.754400255120908 GO:0015385 sodium:proton antiporter activity 2/1510 16/18639 0.125 1.54296357615894 0.376223768300159 0.754400255120908 GO:0015562 efflux transmembrane transporter activity 2/1510 16/18639 0.125 1.54296357615894 0.376223768300159 0.754400255120908 GO:0017070 U6 snRNA binding 2/1510 16/18639 0.125 1.54296357615894 0.376223768300159 0.754400255120908 GO:0022858 alanine transmembrane transporter activity 2/1510 16/18639 0.125 1.54296357615894 0.376223768300159 0.754400255120908 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/1510 16/18639 0.125 1.54296357615894 0.376223768300159 0.754400255120908 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/1510 16/18639 0.125 1.54296357615894 0.376223768300159 0.754400255120908 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/1510 16/18639 0.125 1.54296357615894 0.376223768300159 0.754400255120908 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 15/1510 167/18639 0.0898203592814371 1.10871634215014 0.37731958477947 0.75529084414405 GO:0004521 RNA endonuclease activity 7/1510 73/18639 0.0958904109589041 1.18364329130001 0.379129384763884 0.756301130707988 GO:0043539 protein serine/threonine kinase activator activity 7/1510 73/18639 0.0958904109589041 1.18364329130001 0.379129384763884 0.756301130707988 GO:0032813 tumor necrosis factor receptor superfamily binding 5/1510 50/18639 0.1 1.23437086092715 0.381360317027355 0.758141693713043 GO:0048020 CCR chemokine receptor binding 5/1510 50/18639 0.1 1.23437086092715 0.381360317027355 0.758141693713043 GO:0015179 L-amino acid transmembrane transporter activity 6/1510 62/18639 0.0967741935483871 1.19455244605853 0.388091048043249 0.77020124089405 GO:0000217 DNA secondary structure binding 4/1510 39/18639 0.102564102564103 1.26602139582272 0.389882706564021 0.77204242206974 GO:0003697 single-stranded DNA binding 11/1510 121/18639 0.0909090909090909 1.12215532811559 0.391017171488298 0.77204242206974 GO:0051082 unfolded protein binding 11/1510 121/18639 0.0909090909090909 1.12215532811559 0.391017171488298 0.77204242206974 GO:0003684 damaged DNA binding 7/1510 74/18639 0.0945945945945946 1.16764811168785 0.392727691897462 0.772476641947976 GO:0035064 methylated histone binding 7/1510 74/18639 0.0945945945945946 1.16764811168785 0.392727691897462 0.772476641947976 GO:0015631 tubulin binding 33/1510 385/18639 0.0857142857142857 1.05803216650899 0.393236599438573 0.772476641947976 GO:0045499 chemorepellent activity 3/1510 28/18639 0.107142857142857 1.32254020813623 0.398532781242389 0.777608574848365 GO:0046875 ephrin receptor binding 3/1510 28/18639 0.107142857142857 1.32254020813623 0.398532781242389 0.777608574848365 GO:0051537 2 iron, 2 sulfur cluster binding 3/1510 28/18639 0.107142857142857 1.32254020813623 0.398532781242389 0.777608574848365 GO:0051959 dynein light intermediate chain binding 3/1510 28/18639 0.107142857142857 1.32254020813623 0.398532781242389 0.777608574848365 GO:0000287 magnesium ion binding 20/1510 230/18639 0.0869565217391304 1.07336596602361 0.40422999258034 0.78098495893936 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/1510 17/18639 0.117647058823529 1.45220101285547 0.405809941073194 0.78098495893936 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/1510 17/18639 0.117647058823529 1.45220101285547 0.405809941073194 0.78098495893936 GO:0008569 minus-end-directed microtubule motor activity 2/1510 17/18639 0.117647058823529 1.45220101285547 0.405809941073194 0.78098495893936 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/1510 17/18639 0.117647058823529 1.45220101285547 0.405809941073194 0.78098495893936 GO:0015278 intracellularly gated calcium channel activity 2/1510 17/18639 0.117647058823529 1.45220101285547 0.405809941073194 0.78098495893936 GO:0046965 nuclear retinoid X receptor binding 2/1510 17/18639 0.117647058823529 1.45220101285547 0.405809941073194 0.78098495893936 GO:0070403 NAD+ binding 2/1510 17/18639 0.117647058823529 1.45220101285547 0.405809941073194 0.78098495893936 GO:0044183 protein folding chaperone 7/1510 75/18639 0.0933333333333333 1.15207947019868 0.406327808663015 0.78098495893936 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 4/1510 40/18639 0.1 1.23437086092715 0.408707502445138 0.78166995929689 GO:0061791 GTPase motor activity 4/1510 40/18639 0.1 1.23437086092715 0.408707502445138 0.78166995929689 GO:1990606 membrane scission GTPase motor activity 4/1510 40/18639 0.1 1.23437086092715 0.408707502445138 0.78166995929689 GO:0140034 methylation-dependent protein binding 7/1510 76/18639 0.0921052631578947 1.13692052980132 0.419913687370349 0.799704563915222 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/1510 29/18639 0.103448275862069 1.27693537337292 0.420897138902748 0.799704563915222 GO:0035250 UDP-galactosyltransferase activity 3/1510 29/18639 0.103448275862069 1.27693537337292 0.420897138902748 0.799704563915222 GO:0097472 cyclin-dependent protein kinase activity 3/1510 29/18639 0.103448275862069 1.27693537337292 0.420897138902748 0.799704563915222 GO:0016877 ligase activity, forming carbon-sulfur bonds 4/1510 41/18639 0.0975609756097561 1.20426425456308 0.427410759434889 0.806993516533404 GO:0016860 intramolecular oxidoreductase activity 5/1510 53/18639 0.0943396226415094 1.16450081219543 0.430743418120466 0.806993516533404 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 8/1510 89/18639 0.0898876404494382 1.10954684128283 0.433875294712226 0.806993516533404 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 8/1510 89/18639 0.0898876404494382 1.10954684128283 0.433875294712226 0.806993516533404 GO:0000900 mRNA regulatory element binding translation repressor activity 2/1510 18/18639 0.111111111111111 1.37152317880795 0.434699634494421 0.806993516533404 GO:0004706 JUN kinase kinase kinase activity 2/1510 18/18639 0.111111111111111 1.37152317880795 0.434699634494421 0.806993516533404 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/1510 18/18639 0.111111111111111 1.37152317880795 0.434699634494421 0.806993516533404 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/1510 18/18639 0.111111111111111 1.37152317880795 0.434699634494421 0.806993516533404 GO:0017075 syntaxin-1 binding 2/1510 18/18639 0.111111111111111 1.37152317880795 0.434699634494421 0.806993516533404 GO:0030228 lipoprotein particle receptor activity 2/1510 18/18639 0.111111111111111 1.37152317880795 0.434699634494421 0.806993516533404 GO:0032393 MHC class I receptor activity 2/1510 18/18639 0.111111111111111 1.37152317880795 0.434699634494421 0.806993516533404 GO:0050811 GABA receptor binding 2/1510 18/18639 0.111111111111111 1.37152317880795 0.434699634494421 0.806993516533404 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/1510 18/18639 0.111111111111111 1.37152317880795 0.434699634494421 0.806993516533404 GO:1901611 phosphatidylglycerol binding 2/1510 18/18639 0.111111111111111 1.37152317880795 0.434699634494421 0.806993516533404 GO:0005125 cytokine activity 20/1510 234/18639 0.0854700854700855 1.05501782985227 0.435177694420516 0.806993516533404 GO:0008083 growth factor activity 14/1510 162/18639 0.0864197530864197 1.06674025018396 0.441140229758377 0.813638104779447 GO:0001965 G-protein alpha-subunit binding 3/1510 30/18639 0.1 1.23437086092715 0.442972945742736 0.813638104779447 GO:0008187 poly-pyrimidine tract binding 3/1510 30/18639 0.1 1.23437086092715 0.442972945742736 0.813638104779447 GO:0016769 transferase activity, transferring nitrogenous groups 3/1510 30/18639 0.1 1.23437086092715 0.442972945742736 0.813638104779447 GO:0048019 receptor antagonist activity 3/1510 30/18639 0.1 1.23437086092715 0.442972945742736 0.813638104779447 GO:0070566 adenylyltransferase activity 3/1510 30/18639 0.1 1.23437086092715 0.442972945742736 0.813638104779447 GO:0031492 nucleosomal DNA binding 4/1510 42/18639 0.0952380952380952 1.1755912961211 0.445956498375722 0.814838493741926 GO:0042056 chemoattractant activity 4/1510 42/18639 0.0952380952380952 1.1755912961211 0.445956498375722 0.814838493741926 GO:0019210 kinase inhibitor activity 8/1510 90/18639 0.0888888888888889 1.09721854304636 0.446438691566974 0.814838493741926 GO:0140793 histone H2AXY142 phosphatase activity 8/1510 90/18639 0.0888888888888889 1.09721854304636 0.446438691566974 0.814838493741926 GO:0001664 G protein-coupled receptor binding 25/1510 297/18639 0.0841750841750842 1.03903271121814 0.451085491759667 0.822025290801027 GO:0016791 phosphatase activity 23/1510 273/18639 0.0842490842490843 1.03994614656866 0.453895392954944 0.824313684704213 GO:0004519 endonuclease activity 11/1510 127/18639 0.0866141732283465 1.06914011576368 0.454594194985897 0.824313684704213 GO:0042826 histone deacetylase binding 11/1510 127/18639 0.0866141732283465 1.06914011576368 0.454594194985897 0.824313684704213 GO:0017124 SH3 domain binding 10/1510 115/18639 0.0869565217391304 1.07336596602361 0.456027674422388 0.824313684704213 GO:0004722 protein serine/threonine phosphatase activity 9/1510 103/18639 0.087378640776699 1.07857648042178 0.457484976694255 0.824313684704213 GO:0008173 RNA methyltransferase activity 6/1510 67/18639 0.0895522388059701 1.10540674112879 0.461876614164303 0.824313684704213 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 6/1510 67/18639 0.0895522388059701 1.10540674112879 0.461876614164303 0.824313684704213 GO:0042054 histone methyltransferase activity 6/1510 67/18639 0.0895522388059701 1.10540674112879 0.461876614164303 0.824313684704213 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/1510 19/18639 0.105263157894737 1.29933774834437 0.462811500045694 0.824313684704213 GO:0016918 retinal binding 2/1510 19/18639 0.105263157894737 1.29933774834437 0.462811500045694 0.824313684704213 GO:0031420 alkali metal ion binding 2/1510 19/18639 0.105263157894737 1.29933774834437 0.462811500045694 0.824313684704213 GO:0070003 threonine-type peptidase activity 2/1510 19/18639 0.105263157894737 1.29933774834437 0.462811500045694 0.824313684704213 GO:0140036 ubiquitin-modified protein reader activity 2/1510 19/18639 0.105263157894737 1.29933774834437 0.462811500045694 0.824313684704213 GO:1990380 K48-linked deubiquitinase activity 2/1510 19/18639 0.105263157894737 1.29933774834437 0.462811500045694 0.824313684704213 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4/1510 43/18639 0.0930232558139535 1.14825196365316 0.464311456947737 0.824313684704213 GO:0016878 acid-thiol ligase activity 3/1510 31/18639 0.0967741935483871 1.19455244605853 0.464710149433201 0.824313684704213 GO:0031490 chromatin DNA binding 11/1510 128/18639 0.0859375 1.06078745860927 0.465143356166139 0.824313684704213 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 11/1510 128/18639 0.0859375 1.06078745860927 0.465143356166139 0.824313684704213 GO:1990841 promoter-specific chromatin binding 6/1510 68/18639 0.0882352941176471 1.08915075964161 0.476404439006271 0.842981289783615 GO:0019205 nucleobase-containing compound kinase activity 4/1510 44/18639 0.0909090909090909 1.12215532811559 0.482445072249168 0.851581630585592 GO:0008378 galactosyltransferase activity 3/1510 32/18639 0.09375 1.15722268211921 0.486064638287883 0.851581630585592 GO:0015106 bicarbonate transmembrane transporter activity 3/1510 32/18639 0.09375 1.15722268211921 0.486064638287883 0.851581630585592 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/1510 32/18639 0.09375 1.15722268211921 0.486064638287883 0.851581630585592 GO:0140142 nucleocytoplasmic carrier activity 3/1510 32/18639 0.09375 1.15722268211921 0.486064638287883 0.851581630585592 GO:0016798 hydrolase activity, acting on glycosyl bonds 11/1510 130/18639 0.0846153846153846 1.04446765155374 0.48613687479686 0.851581630585592 GO:0030971 receptor tyrosine kinase binding 7/1510 81/18639 0.0864197530864197 1.06674025018396 0.487103713790084 0.851581630585592 GO:0016874 ligase activity 14/1510 167/18639 0.0838323353293413 1.03480191934013 0.487576003520881 0.851581630585592 GO:0000339 RNA cap binding 2/1510 20/18639 0.1 1.23437086092715 0.490081922002234 0.851581630585592 GO:0016505 peptidase activator activity involved in apoptotic process 2/1510 20/18639 0.1 1.23437086092715 0.490081922002234 0.851581630585592 GO:0052745 inositol phosphate phosphatase activity 2/1510 20/18639 0.1 1.23437086092715 0.490081922002234 0.851581630585592 GO:0061608 nuclear import signal receptor activity 2/1510 20/18639 0.1 1.23437086092715 0.490081922002234 0.851581630585592 GO:0008013 beta-catenin binding 9/1510 106/18639 0.0849056603773585 1.04805073097588 0.492468097349154 0.854446893454596 GO:0030296 protein tyrosine kinase activator activity 3/1510 33/18639 0.0909090909090909 1.12215532811559 0.506997936332135 0.878341716306345 GO:0008236 serine-type peptidase activity 16/1510 194/18639 0.0824742268041237 1.01803782344507 0.508303759042627 0.879289636911051 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/1510 21/18639 0.0952380952380952 1.1755912961211 0.516462681334008 0.883911108227903 GO:0015125 bile acid transmembrane transporter activity 2/1510 21/18639 0.0952380952380952 1.1755912961211 0.516462681334008 0.883911108227903 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 4/1510 46/18639 0.0869565217391304 1.07336596602361 0.517939280073161 0.883911108227903 GO:0140299 molecular sensor activity 6/1510 71/18639 0.0845070422535211 1.04313030500886 0.519225044585577 0.883911108227903 GO:0140996 histone H3 kinase activity 29/1510 357/18639 0.0812324929971989 1.00271022316211 0.522429355243383 0.883911108227903 GO:0001786 phosphatidylserine binding 5/1510 59/18639 0.0847457627118644 1.04607700078572 0.526293112539985 0.883911108227903 GO:0008175 tRNA methyltransferase activity 3/1510 34/18639 0.0882352941176471 1.08915075964161 0.527476882228076 0.883911108227903 GO:0015020 glucuronosyltransferase activity 3/1510 34/18639 0.0882352941176471 1.08915075964161 0.527476882228076 0.883911108227903 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 3/1510 34/18639 0.0882352941176471 1.08915075964161 0.527476882228076 0.883911108227903 GO:0030332 cyclin binding 3/1510 34/18639 0.0882352941176471 1.08915075964161 0.527476882228076 0.883911108227903 GO:0005504 fatty acid binding 4/1510 47/18639 0.0851063829787234 1.05052839227843 0.535251830176182 0.883911108227903 GO:0035173 histone kinase activity 29/1510 360/18639 0.0805555555555556 0.994354304635762 0.541278403745196 0.883911108227903 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/1510 60/18639 0.0833333333333333 1.02864238410596 0.541555965756216 0.883911108227903 GO:0004407 histone deacetylase activity 2/1510 22/18639 0.0909090909090909 1.12215532811559 0.541918881343405 0.883911108227903 GO:0008649 rRNA methyltransferase activity 2/1510 22/18639 0.0909090909090909 1.12215532811559 0.541918881343405 0.883911108227903 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/1510 22/18639 0.0909090909090909 1.12215532811559 0.541918881343405 0.883911108227903 GO:0016881 acid-amino acid ligase activity 2/1510 22/18639 0.0909090909090909 1.12215532811559 0.541918881343405 0.883911108227903 GO:0033558 protein lysine deacetylase activity 2/1510 22/18639 0.0909090909090909 1.12215532811559 0.541918881343405 0.883911108227903 GO:0140517 protein-RNA adaptor activity 2/1510 22/18639 0.0909090909090909 1.12215532811559 0.541918881343405 0.883911108227903 GO:0140784 metal ion sensor activity 2/1510 22/18639 0.0909090909090909 1.12215532811559 0.541918881343405 0.883911108227903 GO:0017171 serine hydrolase activity 16/1510 198/18639 0.0808080808080808 0.997471402769416 0.542183199904123 0.883911108227903 GO:0004725 protein tyrosine phosphatase activity 8/1510 98/18639 0.0816326530612245 1.00764968238951 0.544469066630443 0.883911108227903 GO:0005343 organic acid:sodium symporter activity 3/1510 35/18639 0.0857142857142857 1.05803216650899 0.547473298808933 0.883911108227903 GO:0016229 steroid dehydrogenase activity 3/1510 35/18639 0.0857142857142857 1.05803216650899 0.547473298808933 0.883911108227903 GO:0034061 DNA polymerase activity 3/1510 35/18639 0.0857142857142857 1.05803216650899 0.547473298808933 0.883911108227903 GO:0043015 gamma-tubulin binding 3/1510 35/18639 0.0857142857142857 1.05803216650899 0.547473298808933 0.883911108227903 GO:0050660 flavin adenine dinucleotide binding 7/1510 86/18639 0.0813953488372093 1.00472046819652 0.551843098979329 0.883911108227903 GO:0036121 double-stranded DNA helicase activity 4/1510 48/18639 0.0833333333333333 1.02864238410596 0.552246804627351 0.883911108227903 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 5/1510 61/18639 0.0819672131147541 1.01177939420258 0.556584336255969 0.883911108227903 GO:0042578 phosphoric ester hydrolase activity 29/1510 363/18639 0.0798898071625344 0.986136500465218 0.55992931366438 0.883911108227903 GO:0005158 insulin receptor binding 2/1510 23/18639 0.0869565217391304 1.07336596602361 0.566427108005511 0.883911108227903 GO:0031681 G-protein beta-subunit binding 2/1510 23/18639 0.0869565217391304 1.07336596602361 0.566427108005511 0.883911108227903 GO:0042171 lysophosphatidic acid acyltransferase activity 2/1510 23/18639 0.0869565217391304 1.07336596602361 0.566427108005511 0.883911108227903 GO:0071617 lysophospholipid acyltransferase activity 2/1510 23/18639 0.0869565217391304 1.07336596602361 0.566427108005511 0.883911108227903 GO:0140103 catalytic activity, acting on a glycoprotein 2/1510 23/18639 0.0869565217391304 1.07336596602361 0.566427108005511 0.883911108227903 GO:0044390 ubiquitin-like protein conjugating enzyme binding 3/1510 36/18639 0.0833333333333333 1.02864238410596 0.56696365881607 0.883911108227903 GO:0055106 ubiquitin-protein transferase regulator activity 3/1510 36/18639 0.0833333333333333 1.02864238410596 0.56696365881607 0.883911108227903 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0003796 lysozyme activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0004382 GDP phosphatase activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0004935 adrenergic receptor activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0005131 growth hormone receptor binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0005337 nucleoside transmembrane transporter activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0008140 cAMP response element binding protein binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0015203 polyamine transmembrane transporter activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0016427 tRNA (cytidine) methyltransferase activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0016783 sulfurtransferase activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0016868 intramolecular phosphotransferase activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0031419 cobalamin binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0031720 haptoglobin binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0032356 oxidized DNA binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0035256 G protein-coupled glutamate receptor binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0043121 neurotrophin binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0043295 glutathione binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0051864 histone H3K36 demethylase activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0051880 G-quadruplex DNA binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0070097 delta-catenin binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0070513 death domain binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0070739 protein-glutamic acid ligase activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0070740 tubulin-glutamic acid ligase activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0097177 mitochondrial ribosome binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0098505 G-rich strand telomeric DNA binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0140940 histone H2A methyltransferase activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0141109 transporter activator activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:1905394 retromer complex binding 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:1990259 histone H2AQ104 methyltransferase activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:1990757 ubiquitin ligase activator activity 1/1510 10/18639 0.1 1.23437086092715 0.570462043964169 0.883911108227903 GO:0046906 tetrapyrrole binding 12/1510 152/18639 0.0789473684210526 0.974503311258278 0.580595624134246 0.89628148216361 GO:0141003 histone H2AX kinase activity 28/1510 354/18639 0.0790960451977401 0.976338534066674 0.581782423607294 0.89628148216361 GO:0004175 endopeptidase activity 32/1510 405/18639 0.0790123456790123 0.975305371596762 0.586206173597758 0.89628148216361 GO:0016757 glycosyltransferase activity 21/1510 267/18639 0.0786516853932584 0.970853486122479 0.589498227894593 0.89628148216361 GO:0004622 lysophospholipase activity 2/1510 24/18639 0.0833333333333333 1.02864238410596 0.589973800635293 0.89628148216361 GO:0030215 semaphorin receptor binding 2/1510 24/18639 0.0833333333333333 1.02864238410596 0.589973800635293 0.89628148216361 GO:0030552 cAMP binding 2/1510 24/18639 0.0833333333333333 1.02864238410596 0.589973800635293 0.89628148216361 GO:0004536 DNA nuclease activity 5/1510 64/18639 0.078125 0.964352235099338 0.600131629275197 0.89628148216361 GO:0030544 Hsp70 protein binding 4/1510 51/18639 0.0784313725490196 0.968134008570316 0.601158369053361 0.89628148216361 GO:0002162 dystroglycan binding 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0005225 volume-sensitive anion channel activity 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0005536 D-glucose binding 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0019215 intermediate filament binding 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0034511 U3 snoRNA binding 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0035252 UDP-xylosyltransferase activity 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0042285 xylosyltransferase activity 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0043522 leucine zipper domain binding 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0045294 alpha-catenin binding 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0047676 arachidonate-CoA ligase activity 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0180030 inositol phosphate kinase activity 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:1900750 oligopeptide binding 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:1990948 ubiquitin ligase inhibitor activity 1/1510 11/18639 0.0909090909090909 1.12215532811559 0.605278851823641 0.89628148216361 GO:0020037 heme binding 11/1510 142/18639 0.0774647887323944 0.956202779591456 0.606570924090638 0.89628148216361 GO:0000030 mannosyltransferase activity 2/1510 25/18639 0.08 0.987496688741722 0.612553810911308 0.89628148216361 GO:0005537 D-mannose binding 2/1510 25/18639 0.08 0.987496688741722 0.612553810911308 0.89628148216361 GO:0008483 transaminase activity 2/1510 25/18639 0.08 0.987496688741722 0.612553810911308 0.89628148216361 GO:0015662 P-type ion transporter activity 2/1510 25/18639 0.08 0.987496688741722 0.612553810911308 0.89628148216361 GO:0042974 nuclear retinoic acid receptor binding 2/1510 25/18639 0.08 0.987496688741722 0.612553810911308 0.89628148216361 GO:0140358 P-type transmembrane transporter activity 2/1510 25/18639 0.08 0.987496688741722 0.612553810911308 0.89628148216361 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/1510 39/18639 0.0769230769230769 0.94951604686704 0.622225907220148 0.89628148216361 GO:0052689 carboxylic ester hydrolase activity 7/1510 92/18639 0.0760869565217391 0.939195220270659 0.624424058062142 0.89628148216361 GO:0033293 monocarboxylic acid binding 6/1510 79/18639 0.0759493670886076 0.937496856400369 0.625531461609582 0.89628148216361 GO:0051018 protein kinase A binding 4/1510 53/18639 0.0754716981132075 0.931600649756341 0.631908353090658 0.89628148216361 GO:0015216 purine nucleotide transmembrane transporter activity 2/1510 26/18639 0.0769230769230769 0.94951604686704 0.634169130461417 0.89628148216361 GO:0030507 spectrin binding 2/1510 26/18639 0.0769230769230769 0.94951604686704 0.634169130461417 0.89628148216361 GO:0034237 protein kinase A regulatory subunit binding 2/1510 26/18639 0.0769230769230769 0.94951604686704 0.634169130461417 0.89628148216361 GO:0043548 phosphatidylinositol 3-kinase binding 2/1510 26/18639 0.0769230769230769 0.94951604686704 0.634169130461417 0.89628148216361 GO:0051139 metal cation:proton antiporter activity 2/1510 26/18639 0.0769230769230769 0.94951604686704 0.634169130461417 0.89628148216361 GO:0052742 phosphatidylinositol kinase activity 2/1510 26/18639 0.0769230769230769 0.94951604686704 0.634169130461417 0.89628148216361 GO:0051213 dioxygenase activity 7/1510 93/18639 0.0752688172043011 0.929096346934416 0.635868400061103 0.89628148216361 GO:0000340 RNA 7-methylguanosine cap binding 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0003995 acyl-CoA dehydrogenase activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0004000 adenosine deaminase activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0004300 enoyl-CoA hydratase activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0004875 complement receptor activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0005025 transforming growth factor beta receptor activity, type I 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0005026 transforming growth factor beta receptor activity, type II 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0005049 nuclear export signal receptor activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0005095 GTPase inhibitor activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0005247 voltage-gated chloride channel activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0008179 adenylate cyclase binding 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0015132 prostaglandin transmembrane transporter activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0015166 polyol transmembrane transporter activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0015368 calcium:monoatomic cation antiporter activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0016361 activin receptor activity, type I 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0016362 activin receptor activity, type II 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0017002 activin receptor activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0017166 vinculin binding 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0031543 peptidyl-proline dioxygenase activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0035197 siRNA binding 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0036009 protein-glutamine N-methyltransferase activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0043047 single-stranded telomeric DNA binding 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0045295 gamma-catenin binding 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:1990459 transferrin receptor binding 1/1510 12/18639 0.0833333333333333 1.02864238410596 0.637275251530872 0.89628148216361 GO:0032451 demethylase activity 3/1510 40/18639 0.075 0.925778145695364 0.639538210310013 0.89628148216361 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/1510 40/18639 0.075 0.925778145695364 0.639538210310013 0.89628148216361 GO:0071949 FAD binding 3/1510 40/18639 0.075 0.925778145695364 0.639538210310013 0.89628148216361 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/1510 54/18639 0.0740740740740741 0.914348785871965 0.646697536731208 0.904779425904888 GO:0001671 ATPase activator activity 2/1510 27/18639 0.0740740740740741 0.914348785871965 0.654827769183859 0.904779425904888 GO:0005104 fibroblast growth factor receptor binding 2/1510 27/18639 0.0740740740740741 0.914348785871965 0.654827769183859 0.904779425904888 GO:0008320 protein transmembrane transporter activity 2/1510 27/18639 0.0740740740740741 0.914348785871965 0.654827769183859 0.904779425904888 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/1510 27/18639 0.0740740740740741 0.914348785871965 0.654827769183859 0.904779425904888 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/1510 27/18639 0.0740740740740741 0.914348785871965 0.654827769183859 0.904779425904888 GO:0001727 lipid kinase activity 3/1510 41/18639 0.0731707317073171 0.903198190922307 0.656285114326471 0.904779425904888 GO:0004812 aminoacyl-tRNA ligase activity 3/1510 41/18639 0.0731707317073171 0.903198190922307 0.656285114326471 0.904779425904888 GO:0016875 ligase activity, forming carbon-oxygen bonds 3/1510 41/18639 0.0731707317073171 0.903198190922307 0.656285114326471 0.904779425904888 GO:0140318 protein transporter activity 3/1510 41/18639 0.0731707317073171 0.903198190922307 0.656285114326471 0.904779425904888 GO:0140828 metal cation:monoatomic cation antiporter activity 3/1510 41/18639 0.0731707317073171 0.903198190922307 0.656285114326471 0.904779425904888 GO:0031406 carboxylic acid binding 14/1510 187/18639 0.0748663101604278 0.924127917271665 0.66050830676003 0.904779425904888 GO:0003823 antigen binding 13/1510 174/18639 0.0747126436781609 0.922231102991551 0.660559636635953 0.904779425904888 GO:0015297 antiporter activity 10/1510 135/18639 0.0740740740740741 0.914348785871965 0.662392050265881 0.904779425904888 GO:0002161 aminoacyl-tRNA editing activity 1/1510 13/18639 0.0769230769230769 0.94951604686704 0.666679576982549 0.904779425904888 GO:0009982 pseudouridine synthase activity 1/1510 13/18639 0.0769230769230769 0.94951604686704 0.666679576982549 0.904779425904888 GO:0017154 semaphorin receptor activity 1/1510 13/18639 0.0769230769230769 0.94951604686704 0.666679576982549 0.904779425904888 GO:0032396 inhibitory MHC class I receptor activity 1/1510 13/18639 0.0769230769230769 0.94951604686704 0.666679576982549 0.904779425904888 GO:0039706 co-receptor binding 1/1510 13/18639 0.0769230769230769 0.94951604686704 0.666679576982549 0.904779425904888 GO:0043560 insulin receptor substrate binding 1/1510 13/18639 0.0769230769230769 0.94951604686704 0.666679576982549 0.904779425904888 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/1510 13/18639 0.0769230769230769 0.94951604686704 0.666679576982549 0.904779425904888 GO:0045159 myosin II binding 1/1510 13/18639 0.0769230769230769 0.94951604686704 0.666679576982549 0.904779425904888 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/1510 13/18639 0.0769230769230769 0.94951604686704 0.666679576982549 0.904779425904888 GO:0071714 icosanoid transmembrane transporter activity 1/1510 13/18639 0.0769230769230769 0.94951604686704 0.666679576982549 0.904779425904888 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/1510 13/18639 0.0769230769230769 0.94951604686704 0.666679576982549 0.904779425904888 GO:0097157 pre-mRNA intronic binding 1/1510 13/18639 0.0769230769230769 0.94951604686704 0.666679576982549 0.904779425904888 GO:1901338 catecholamine binding 1/1510 13/18639 0.0769230769230769 0.94951604686704 0.666679576982549 0.904779425904888 GO:0016866 intramolecular transferase activity 2/1510 28/18639 0.0714285714285714 0.881693472090823 0.674542768256279 0.914139894180794 GO:0043177 organic acid binding 14/1510 189/18639 0.0740740740740741 0.914348785871965 0.675995321155861 0.914139894180794 GO:0004252 serine-type endopeptidase activity 13/1510 176/18639 0.0738636363636364 0.911751204093919 0.676587495204932 0.914139894180794 GO:0008170 N-methyltransferase activity 7/1510 98/18639 0.0714285714285714 0.881693472090823 0.689974326485661 0.914139894180794 GO:0004629 phospholipase C activity 2/1510 29/18639 0.0689655172413793 0.851290248915277 0.693331333393578 0.914139894180794 GO:0099604 ligand-gated calcium channel activity 2/1510 29/18639 0.0689655172413793 0.851290248915277 0.693331333393578 0.914139894180794 GO:0005344 oxygen carrier activity 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0008174 mRNA methyltransferase activity 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0008195 phosphatidate phosphatase activity 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0015386 potassium:proton antiporter activity 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0016530 metallochaperone activity 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0030983 mismatched DNA binding 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0031404 chloride ion binding 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0034236 protein kinase A catalytic subunit binding 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0042813 Wnt receptor activity 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0043176 amine binding 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0061665 SUMO ligase activity 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0061783 peptidoglycan muralytic activity 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0098599 palmitoyl hydrolase activity 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0098821 BMP receptor activity 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0098847 sequence-specific single stranded DNA binding 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:1901474 azole transmembrane transporter activity 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:1901612 cardiolipin binding 1/1510 14/18639 0.0714285714285714 0.881693472090823 0.693701687943375 0.914139894180794 GO:0140101 catalytic activity, acting on a tRNA 10/1510 139/18639 0.0719424460431655 0.888036590595074 0.697887796935893 0.914139894180794 GO:0017116 single-stranded DNA helicase activity 4/1510 58/18639 0.0689655172413793 0.851290248915277 0.701829494713733 0.914139894180794 GO:0001046 core promoter sequence-specific DNA binding 3/1510 44/18639 0.0681818181818182 0.841616496086695 0.703121840549797 0.914139894180794 GO:0001223 transcription coactivator binding 3/1510 44/18639 0.0681818181818182 0.841616496086695 0.703121840549797 0.914139894180794 GO:0030020 extracellular matrix structural constituent conferring tensile strength 3/1510 44/18639 0.0681818181818182 0.841616496086695 0.703121840549797 0.914139894180794 GO:0016853 isomerase activity 13/1510 180/18639 0.0722222222222222 0.891490066225165 0.707308353604202 0.914139894180794 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/1510 30/18639 0.0666666666666667 0.822913907284768 0.711214075368638 0.914139894180794 GO:0015215 nucleotide transmembrane transporter activity 2/1510 30/18639 0.0666666666666667 0.822913907284768 0.711214075368638 0.914139894180794 GO:0031624 ubiquitin conjugating enzyme binding 2/1510 30/18639 0.0666666666666667 0.822913907284768 0.711214075368638 0.914139894180794 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/1510 30/18639 0.0666666666666667 0.822913907284768 0.711214075368638 0.914139894180794 GO:0051721 protein phosphatase 2A binding 2/1510 30/18639 0.0666666666666667 0.822913907284768 0.711214075368638 0.914139894180794 GO:0005506 iron ion binding 11/1510 154/18639 0.0714285714285714 0.881693472090823 0.711705210896282 0.914139894180794 GO:0004879 nuclear receptor activity 4/1510 59/18639 0.0677966101694915 0.836861600628578 0.714595777053642 0.914139894180794 GO:0015459 potassium channel regulator activity 4/1510 59/18639 0.0677966101694915 0.836861600628578 0.714595777053642 0.914139894180794 GO:0035402 histone H3T11 kinase activity 18/1510 247/18639 0.0728744939271255 0.899541518084564 0.714976993071359 0.914139894180794 GO:0016247 channel regulator activity 12/1510 168/18639 0.0714285714285714 0.881693472090823 0.716903916035126 0.914139894180794 GO:0008081 phosphoric diester hydrolase activity 6/1510 87/18639 0.0689655172413793 0.851290248915277 0.716905602392595 0.914139894180794 GO:0000774 adenyl-nucleotide exchange factor activity 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0004467 long-chain fatty acid-CoA ligase activity 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0015116 sulfate transmembrane transporter activity 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0031386 protein tag activity 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0033130 acetylcholine receptor binding 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0047372 monoacylglycerol lipase activity 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0050700 CARD domain binding 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0140776 protein-containing complex destabilizing activity 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0141047 molecular tag activity 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0141050 histone H3K deacetylase activity 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0141051 histone H4K deacetylase activity 1/1510 15/18639 0.0666666666666667 0.822913907284768 0.718534463847026 0.914139894180794 GO:0004679 AMP-activated protein kinase activity 18/1510 248/18639 0.0725806451612903 0.895914334543901 0.721246334393495 0.916583883291733 GO:0003678 DNA helicase activity 5/1510 74/18639 0.0675675675675676 0.834034365491319 0.726089614397617 0.921397846240538 GO:0098531 ligand-modulated transcription factor activity 4/1510 60/18639 0.0666666666666667 0.822913907284768 0.726955763574887 0.921397846240538 GO:0016411 acylglycerol O-acyltransferase activity 2/1510 31/18639 0.0645161290322581 0.796368297372356 0.728214346122806 0.921397846240538 GO:0017147 Wnt-protein binding 2/1510 31/18639 0.0645161290322581 0.796368297372356 0.728214346122806 0.921397846240538 GO:0015171 amino acid transmembrane transporter activity 7/1510 102/18639 0.0686274509803922 0.847117257499026 0.729333551300784 0.921807618274382 GO:0004180 carboxypeptidase activity 3/1510 46/18639 0.0652173913043478 0.805024474517708 0.731537318603664 0.922901747517994 GO:0141108 transporter regulator activity 12/1510 170/18639 0.0705882352941176 0.871320607713284 0.73179180842885 0.922901747517994 GO:0000062 fatty-acyl-CoA binding 1/1510 16/18639 0.0625 0.77148178807947 0.741355176883484 0.922911546732501 GO:0003688 DNA replication origin binding 1/1510 16/18639 0.0625 0.77148178807947 0.741355176883484 0.922911546732501 GO:0005149 interleukin-1 receptor binding 1/1510 16/18639 0.0625 0.77148178807947 0.741355176883484 0.922911546732501 GO:0008142 oxysterol binding 1/1510 16/18639 0.0625 0.77148178807947 0.741355176883484 0.922911546732501 GO:0015378 sodium:chloride symporter activity 1/1510 16/18639 0.0625 0.77148178807947 0.741355176883484 0.922911546732501 GO:0019841 retinol binding 1/1510 16/18639 0.0625 0.77148178807947 0.741355176883484 0.922911546732501 GO:0022841 potassium ion leak channel activity 1/1510 16/18639 0.0625 0.77148178807947 0.741355176883484 0.922911546732501 GO:0030275 LRR domain binding 1/1510 16/18639 0.0625 0.77148178807947 0.741355176883484 0.922911546732501 GO:0070411 I-SMAD binding 1/1510 16/18639 0.0625 0.77148178807947 0.741355176883484 0.922911546732501 GO:0097027 ubiquitin-protein transferase activator activity 1/1510 16/18639 0.0625 0.77148178807947 0.741355176883484 0.922911546732501 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/1510 16/18639 0.0625 0.77148178807947 0.741355176883484 0.922911546732501 GO:0140328 floppase activity 1/1510 16/18639 0.0625 0.77148178807947 0.741355176883484 0.922911546732501 GO:0022884 macromolecule transmembrane transporter activity 2/1510 32/18639 0.0625 0.77148178807947 0.744357659978468 0.923382638375663 GO:0051059 NF-kappaB binding 2/1510 32/18639 0.0625 0.77148178807947 0.744357659978468 0.923382638375663 GO:0061749 forked DNA-dependent helicase activity 3/1510 47/18639 0.0638297872340425 0.787896294208821 0.744920420087356 0.923382638375663 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/1510 47/18639 0.0638297872340425 0.787896294208821 0.744920420087356 0.923382638375663 GO:0016829 lyase activity 14/1510 200/18639 0.07 0.864059602649007 0.753628482347618 0.925304564568068 GO:0099106 ion channel regulator activity 11/1510 160/18639 0.06875 0.848629966887417 0.756999193666015 0.925304564568068 GO:0009378 four-way junction helicase activity 3/1510 48/18639 0.0625 0.77148178807947 0.757765327784689 0.925304564568068 GO:0043138 3'-5' DNA helicase activity 3/1510 48/18639 0.0625 0.77148178807947 0.757765327784689 0.925304564568068 GO:0071889 14-3-3 protein binding 2/1510 33/18639 0.0606060606060606 0.748103552077062 0.759671190536296 0.925304564568068 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/1510 17/18639 0.0588235294117647 0.726100506427737 0.762326754121627 0.925304564568068 GO:0004659 prenyltransferase activity 1/1510 17/18639 0.0588235294117647 0.726100506427737 0.762326754121627 0.925304564568068 GO:0017110 nucleoside diphosphate phosphatase activity 1/1510 17/18639 0.0588235294117647 0.726100506427737 0.762326754121627 0.925304564568068 GO:0030169 low-density lipoprotein particle binding 1/1510 17/18639 0.0588235294117647 0.726100506427737 0.762326754121627 0.925304564568068 GO:0031489 myosin V binding 1/1510 17/18639 0.0588235294117647 0.726100506427737 0.762326754121627 0.925304564568068 GO:0036041 long-chain fatty acid binding 1/1510 17/18639 0.0588235294117647 0.726100506427737 0.762326754121627 0.925304564568068 GO:0038191 neuropilin binding 1/1510 17/18639 0.0588235294117647 0.726100506427737 0.762326754121627 0.925304564568068 GO:1901567 fatty acid derivative binding 1/1510 17/18639 0.0588235294117647 0.726100506427737 0.762326754121627 0.925304564568068 GO:0035254 glutamate receptor binding 3/1510 49/18639 0.0612244897959184 0.755737261792134 0.770082221827459 0.925304564568068 GO:0060590 ATPase regulator activity 3/1510 49/18639 0.0612244897959184 0.755737261792134 0.770082221827459 0.925304564568068 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 17/1510 243/18639 0.0699588477366255 0.8635516311013 0.770385878231938 0.925304564568068 GO:0051427 hormone receptor binding 2/1510 34/18639 0.0588235294117647 0.726100506427737 0.77418333480556 0.925304564568068 GO:0005096 GTPase activator activity 19/1510 271/18639 0.0701107011070111 0.865426064856675 0.777164253969471 0.925304564568068 GO:0004676 3-phosphoinositide-dependent protein kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0004711 ribosomal protein S6 kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0035175 histone H3S10 kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0035979 histone H2AXS139 kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0044022 histone H3S28 kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0044023 histone H4S1 kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0044024 histone H2AS1 kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0044025 histone H2BS14 kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0072354 histone H3T3 kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0072371 histone H2AS121 kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0072518 Rho-dependent protein serine/threonine kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0140823 histone H2BS36 kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0140855 histone H3S57 kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0140995 histone H2A kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0140997 histone H4 kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0140998 histone H2B kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:1990244 histone H2AT120 kinase activity 17/1510 245/18639 0.0693877551020408 0.856502230031085 0.781483592184186 0.925304564568068 GO:0000400 four-way junction DNA binding 1/1510 18/18639 0.0555555555555556 0.685761589403973 0.78159893762911 0.925304564568068 GO:0003746 translation elongation factor activity 1/1510 18/18639 0.0555555555555556 0.685761589403973 0.78159893762911 0.925304564568068 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/1510 18/18639 0.0555555555555556 0.685761589403973 0.78159893762911 0.925304564568068 GO:0008308 voltage-gated monoatomic anion channel activity 1/1510 18/18639 0.0555555555555556 0.685761589403973 0.78159893762911 0.925304564568068 GO:0015172 acidic amino acid transmembrane transporter activity 1/1510 18/18639 0.0555555555555556 0.685761589403973 0.78159893762911 0.925304564568068 GO:0015373 monoatomic anion:sodium symporter activity 1/1510 18/18639 0.0555555555555556 0.685761589403973 0.78159893762911 0.925304564568068 GO:0016854 racemase and epimerase activity 1/1510 18/18639 0.0555555555555556 0.685761589403973 0.78159893762911 0.925304564568068 GO:0031690 adrenergic receptor binding 1/1510 18/18639 0.0555555555555556 0.685761589403973 0.78159893762911 0.925304564568068 GO:0034185 apolipoprotein binding 1/1510 18/18639 0.0555555555555556 0.685761589403973 0.78159893762911 0.925304564568068 GO:0160215 deacylase activity 4/1510 65/18639 0.0615384615384615 0.759612837493632 0.782770872418935 0.925746368503617 GO:0004677 DNA-dependent protein kinase activity 17/1510 246/18639 0.0691056910569106 0.853020513648845 0.786892400972863 0.926414569429294 GO:0140857 histone H3T45 kinase activity 17/1510 246/18639 0.0691056910569106 0.853020513648845 0.786892400972863 0.926414569429294 GO:0005154 epidermal growth factor receptor binding 2/1510 35/18639 0.0571428571428571 0.705354777672658 0.787923336987174 0.926414569429294 GO:0140566 histone reader activity 2/1510 35/18639 0.0571428571428571 0.705354777672658 0.787923336987174 0.926414569429294 GO:0035403 histone H3T6 kinase activity 17/1510 247/18639 0.0688259109311741 0.849566989302089 0.792207887643845 0.926414569429294 GO:0015101 organic cation transmembrane transporter activity 5/1510 81/18639 0.0617283950617284 0.761957321559971 0.795520807511008 0.926414569429294 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/1510 19/18639 0.0526315789473684 0.649668874172185 0.799309350828189 0.926414569429294 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1510 19/18639 0.0526315789473684 0.649668874172185 0.799309350828189 0.926414569429294 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/1510 19/18639 0.0526315789473684 0.649668874172185 0.799309350828189 0.926414569429294 GO:0008301 DNA binding, bending 1/1510 19/18639 0.0526315789473684 0.649668874172185 0.799309350828189 0.926414569429294 GO:0022821 solute:potassium antiporter activity 1/1510 19/18639 0.0526315789473684 0.649668874172185 0.799309350828189 0.926414569429294 GO:0022840 leak channel activity 1/1510 19/18639 0.0526315789473684 0.649668874172185 0.799309350828189 0.926414569429294 GO:0022842 narrow pore channel activity 1/1510 19/18639 0.0526315789473684 0.649668874172185 0.799309350828189 0.926414569429294 GO:0034987 immunoglobulin receptor binding 1/1510 19/18639 0.0526315789473684 0.649668874172185 0.799309350828189 0.926414569429294 GO:0042577 lipid phosphatase activity 1/1510 19/18639 0.0526315789473684 0.649668874172185 0.799309350828189 0.926414569429294 GO:0046527 glucosyltransferase activity 1/1510 19/18639 0.0526315789473684 0.649668874172185 0.799309350828189 0.926414569429294 GO:0046624 sphingolipid transporter activity 1/1510 19/18639 0.0526315789473684 0.649668874172185 0.799309350828189 0.926414569429294 GO:0120227 acyl-CoA binding 1/1510 19/18639 0.0526315789473684 0.649668874172185 0.799309350828189 0.926414569429294 GO:0141147 intracellularly calcium-gated channel activity 1/1510 19/18639 0.0526315789473684 0.649668874172185 0.799309350828189 0.926414569429294 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/1510 36/18639 0.0555555555555556 0.685761589403973 0.800920965114886 0.926414569429294 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/1510 36/18639 0.0555555555555556 0.685761589403973 0.800920965114886 0.926414569429294 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/1510 36/18639 0.0555555555555556 0.685761589403973 0.800920965114886 0.926414569429294 GO:0005548 phospholipid transporter activity 4/1510 68/18639 0.0588235294117647 0.726100506427737 0.811657760626506 0.934053765581278 GO:0019213 deacetylase activity 2/1510 37/18639 0.0540540540540541 0.667227492393055 0.813206234468302 0.934053765581278 GO:0030551 cyclic nucleotide binding 2/1510 37/18639 0.0540540540540541 0.667227492393055 0.813206234468302 0.934053765581278 GO:0005246 calcium channel regulator activity 3/1510 53/18639 0.0566037735849057 0.698700487317256 0.814305013437884 0.934053765581278 GO:0001614 purinergic nucleotide receptor activity 1/1510 20/18639 0.05 0.617185430463576 0.815584478661133 0.934053765581278 GO:0001972 retinoic acid binding 1/1510 20/18639 0.05 0.617185430463576 0.815584478661133 0.934053765581278 GO:0015095 magnesium ion transmembrane transporter activity 1/1510 20/18639 0.05 0.617185430463576 0.815584478661133 0.934053765581278 GO:0016004 phospholipase activator activity 1/1510 20/18639 0.05 0.617185430463576 0.815584478661133 0.934053765581278 GO:0016502 nucleotide receptor activity 1/1510 20/18639 0.05 0.617185430463576 0.815584478661133 0.934053765581278 GO:0140939 histone H4 methyltransferase activity 1/1510 20/18639 0.05 0.617185430463576 0.815584478661133 0.934053765581278 GO:0016279 protein-lysine N-methyltransferase activity 4/1510 69/18639 0.0579710144927536 0.715577310682407 0.820560098720323 0.938824436739244 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/1510 70/18639 0.0571428571428571 0.705354777672658 0.829112305202813 0.941875263134404 GO:0016278 lysine N-methyltransferase activity 4/1510 70/18639 0.0571428571428571 0.705354777672658 0.829112305202813 0.941875263134404 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/1510 21/18639 0.0476190476190476 0.587795648060549 0.83054056852749 0.941875263134404 GO:0005123 death receptor binding 1/1510 21/18639 0.0476190476190476 0.587795648060549 0.83054056852749 0.941875263134404 GO:0015174 basic amino acid transmembrane transporter activity 1/1510 21/18639 0.0476190476190476 0.587795648060549 0.83054056852749 0.941875263134404 GO:0035613 RNA stem-loop binding 1/1510 21/18639 0.0476190476190476 0.587795648060549 0.83054056852749 0.941875263134404 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/1510 21/18639 0.0476190476190476 0.587795648060549 0.83054056852749 0.941875263134404 GO:0051428 peptide hormone receptor binding 1/1510 21/18639 0.0476190476190476 0.587795648060549 0.83054056852749 0.941875263134404 GO:0061891 calcium ion sensor activity 1/1510 21/18639 0.0476190476190476 0.587795648060549 0.83054056852749 0.941875263134404 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 34/1510 484/18639 0.0702479338842975 0.86712002627114 0.832195508814577 0.942829515851511 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/1510 39/18639 0.0512820512820513 0.63301069791136 0.835759619071275 0.94594277197618 GO:0015294 solute:monoatomic cation symporter activity 7/1510 116/18639 0.0603448275862069 0.744878967800868 0.839159513482826 0.9488642693918 GO:0005243 gap junction channel activity 1/1510 22/18639 0.0454545454545455 0.561077664057797 0.844284458393399 0.950948189774489 GO:0015377 chloride:monoatomic cation symporter activity 1/1510 22/18639 0.0454545454545455 0.561077664057797 0.844284458393399 0.950948189774489 GO:0031683 G-protein beta/gamma-subunit complex binding 1/1510 22/18639 0.0454545454545455 0.561077664057797 0.844284458393399 0.950948189774489 GO:0050321 tau-protein kinase activity 1/1510 22/18639 0.0454545454545455 0.561077664057797 0.844284458393399 0.950948189774489 GO:0015036 disulfide oxidoreductase activity 2/1510 40/18639 0.05 0.617185430463576 0.846087061637658 0.952053305279655 GO:0030695 GTPase regulator activity 34/1510 489/18639 0.0695296523517382 0.858253768333807 0.848296229310768 0.953613316945859 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/1510 57/18639 0.0526315789473684 0.649668874172185 0.851093459071805 0.954047759550015 GO:0060589 nucleoside-triphosphatase regulator activity 34/1510 490/18639 0.0693877551020408 0.856502230031085 0.851376377847589 0.954047759550015 GO:0001216 DNA-binding transcription activator activity 34/1510 491/18639 0.0692464358452139 0.854757826303934 0.854410356983302 0.954047759550015 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/1510 41/18639 0.0487804878048781 0.602132127281538 0.855820494833103 0.954047759550015 GO:0017080 sodium channel regulator activity 2/1510 41/18639 0.0487804878048781 0.602132127281538 0.855820494833103 0.954047759550015 GO:0000295 adenine nucleotide transmembrane transporter activity 1/1510 23/18639 0.0434782608695652 0.536682983011805 0.856914337956484 0.954047759550015 GO:0005283 amino acid:sodium symporter activity 1/1510 23/18639 0.0434782608695652 0.536682983011805 0.856914337956484 0.954047759550015 GO:0043274 phospholipase binding 1/1510 23/18639 0.0434782608695652 0.536682983011805 0.856914337956484 0.954047759550015 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1510 23/18639 0.0434782608695652 0.536682983011805 0.856914337956484 0.954047759550015 GO:0099186 structural constituent of postsynapse 1/1510 23/18639 0.0434782608695652 0.536682983011805 0.856914337956484 0.954047759550015 GO:0016859 cis-trans isomerase activity 2/1510 42/18639 0.0476190476190476 0.587795648060549 0.864988307643239 0.957768981494282 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/1510 24/18639 0.0416666666666667 0.51432119205298 0.868520448274797 0.957768981494282 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/1510 24/18639 0.0416666666666667 0.51432119205298 0.868520448274797 0.957768981494282 GO:0005315 phosphate transmembrane transporter activity 1/1510 24/18639 0.0416666666666667 0.51432119205298 0.868520448274797 0.957768981494282 GO:0005540 hyaluronic acid binding 1/1510 24/18639 0.0416666666666667 0.51432119205298 0.868520448274797 0.957768981494282 GO:0015149 hexose transmembrane transporter activity 1/1510 24/18639 0.0416666666666667 0.51432119205298 0.868520448274797 0.957768981494282 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/1510 24/18639 0.0416666666666667 0.51432119205298 0.868520448274797 0.957768981494282 GO:0055056 D-glucose transmembrane transporter activity 1/1510 24/18639 0.0416666666666667 0.51432119205298 0.868520448274797 0.957768981494282 GO:0060229 lipase activator activity 1/1510 24/18639 0.0416666666666667 0.51432119205298 0.868520448274797 0.957768981494282 GO:0140612 DNA damage sensor activity 1/1510 24/18639 0.0416666666666667 0.51432119205298 0.868520448274797 0.957768981494282 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 7/1510 122/18639 0.0573770491803279 0.708245575941809 0.873815885292133 0.962692596058538 GO:0003707 nuclear steroid receptor activity 1/1510 25/18639 0.04 0.493748344370861 0.879185724831609 0.964026731390572 GO:0015271 outward rectifier potassium channel activity 1/1510 25/18639 0.04 0.493748344370861 0.879185724831609 0.964026731390572 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/1510 25/18639 0.04 0.493748344370861 0.879185724831609 0.964026731390572 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/1510 25/18639 0.04 0.493748344370861 0.879185724831609 0.964026731390572 GO:0047617 fatty acyl-CoA hydrolase activity 1/1510 25/18639 0.04 0.493748344370861 0.879185724831609 0.964026731390572 GO:0016790 thiolester hydrolase activity 2/1510 44/18639 0.0454545454545455 0.561077664057797 0.881737064911352 0.964247907569154 GO:0043014 alpha-tubulin binding 2/1510 44/18639 0.0454545454545455 0.561077664057797 0.881737064911352 0.964247907569154 GO:0140767 enzyme-substrate adaptor activity 8/1510 139/18639 0.0575539568345324 0.710429272476059 0.884130201726136 0.964247907569154 GO:0008514 organic anion transmembrane transporter activity 17/1510 269/18639 0.0631970260223048 0.780085674191881 0.886350044334479 0.964247907569154 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/1510 26/18639 0.0384615384615385 0.47475802343352 0.888986388606417 0.964247907569154 GO:0004435 phosphatidylinositol phospholipase C activity 1/1510 26/18639 0.0384615384615385 0.47475802343352 0.888986388606417 0.964247907569154 GO:0005112 Notch binding 1/1510 26/18639 0.0384615384615385 0.47475802343352 0.888986388606417 0.964247907569154 GO:0005227 calcium-activated cation channel activity 1/1510 26/18639 0.0384615384615385 0.47475802343352 0.888986388606417 0.964247907569154 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/1510 26/18639 0.0384615384615385 0.47475802343352 0.888986388606417 0.964247907569154 GO:0015145 monosaccharide transmembrane transporter activity 1/1510 26/18639 0.0384615384615385 0.47475802343352 0.888986388606417 0.964247907569154 GO:0016289 acyl-CoA hydrolase activity 1/1510 26/18639 0.0384615384615385 0.47475802343352 0.888986388606417 0.964247907569154 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/1510 45/18639 0.0444444444444444 0.548609271523179 0.889371020872671 0.964247907569154 GO:0015370 solute:sodium symporter activity 4/1510 79/18639 0.0506329113924051 0.624997904266913 0.891772883492799 0.965948385016966 GO:0008395 steroid hydroxylase activity 1/1510 27/18639 0.037037037037037 0.457174392935982 0.897992489353438 0.969296190861845 GO:0035255 ionotropic glutamate receptor binding 1/1510 27/18639 0.037037037037037 0.457174392935982 0.897992489353438 0.969296190861845 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/1510 27/18639 0.037037037037037 0.457174392935982 0.897992489353438 0.969296190861845 GO:0005085 guanyl-nucleotide exchange factor activity 14/1510 230/18639 0.0608695652173913 0.751356176216528 0.898208894724436 0.969296190861845 GO:0046943 carboxylic acid transmembrane transporter activity 11/1510 188/18639 0.0585106382978723 0.722238269691419 0.903180034025516 0.973754101800533 GO:0051119 sugar transmembrane transporter activity 1/1510 28/18639 0.0357142857142857 0.440846736045412 0.906268404949629 0.974754502004909 GO:0141052 histone H3 demethylase activity 1/1510 28/18639 0.0357142857142857 0.440846736045412 0.906268404949629 0.974754502004909 GO:0005342 organic acid transmembrane transporter activity 11/1510 189/18639 0.0582010582010582 0.718416903185115 0.906631020846671 0.974754502004909 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/1510 48/18639 0.0416666666666667 0.51432119205298 0.909611068599761 0.975855660642821 GO:0038187 pattern recognition receptor activity 2/1510 48/18639 0.0416666666666667 0.51432119205298 0.909611068599761 0.975855660642821 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 7/1510 130/18639 0.0538461538461538 0.664661232806928 0.910181164068067 0.975855660642821 GO:0005254 chloride channel activity 4/1510 83/18639 0.0481927710843374 0.594877523338387 0.912457558724077 0.976201986285676 GO:0003785 actin monomer binding 1/1510 29/18639 0.0344827586206897 0.425645124457639 0.913873300362345 0.976201986285676 GO:0004181 metallocarboxypeptidase activity 1/1510 29/18639 0.0344827586206897 0.425645124457639 0.913873300362345 0.976201986285676 GO:0005416 amino acid:monoatomic cation symporter activity 1/1510 29/18639 0.0344827586206897 0.425645124457639 0.913873300362345 0.976201986285676 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/1510 30/18639 0.0333333333333333 0.411456953642384 0.920861549500059 0.979427188401232 GO:0022839 monoatomic ion-gated channel activity 1/1510 30/18639 0.0333333333333333 0.411456953642384 0.920861549500059 0.979427188401232 GO:0032452 histone demethylase activity 1/1510 30/18639 0.0333333333333333 0.411456953642384 0.920861549500059 0.979427188401232 GO:0098918 structural constituent of synapse 1/1510 30/18639 0.0333333333333333 0.411456953642384 0.920861549500059 0.979427188401232 GO:0015605 organophosphate ester transmembrane transporter activity 2/1510 50/18639 0.04 0.493748344370861 0.921117890731098 0.979427188401232 GO:0016830 carbon-carbon lyase activity 2/1510 51/18639 0.0392156862745098 0.484067004285158 0.926339946462652 0.982377641219723 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/1510 31/18639 0.032258064516129 0.398184148686178 0.927283122945968 0.982377641219723 GO:0070273 phosphatidylinositol-4-phosphate binding 1/1510 31/18639 0.032258064516129 0.398184148686178 0.927283122945968 0.982377641219723 GO:0140457 protein demethylase activity 1/1510 31/18639 0.032258064516129 0.398184148686178 0.927283122945968 0.982377641219723 GO:0016782 transferase activity, transferring sulphur-containing groups 3/1510 70/18639 0.0428571428571429 0.529016083254494 0.930280395851935 0.984652948668852 GO:0015108 chloride transmembrane transporter activity 6/1510 121/18639 0.0495867768595041 0.612084724426687 0.933859070567923 0.986910942050169 GO:0015291 secondary active transmembrane transporter activity 17/1510 287/18639 0.0592334494773519 0.731160440270439 0.934922859843805 0.986910942050169 GO:0005544 calcium-dependent phospholipid binding 2/1510 53/18639 0.0377358490566038 0.465800324878171 0.935819780252921 0.986910942050169 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/1510 53/18639 0.0377358490566038 0.465800324878171 0.935819780252921 0.986910942050169 GO:0019239 deaminase activity 1/1510 33/18639 0.0303030303030303 0.374051776038531 0.938606217888133 0.988051413744183 GO:0019956 chemokine binding 1/1510 33/18639 0.0303030303030303 0.374051776038531 0.938606217888133 0.988051413744183 GO:0015035 protein-disulfide reductase activity 1/1510 34/18639 0.0294117647058824 0.363050253213868 0.943588729496695 0.988484259423288 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/1510 34/18639 0.0294117647058824 0.363050253213868 0.943588729496695 0.988484259423288 GO:0016831 carboxy-lyase activity 1/1510 34/18639 0.0294117647058824 0.363050253213868 0.943588729496695 0.988484259423288 GO:0019825 oxygen binding 1/1510 34/18639 0.0294117647058824 0.363050253213868 0.943588729496695 0.988484259423288 GO:0090482 vitamin transmembrane transporter activity 1/1510 34/18639 0.0294117647058824 0.363050253213868 0.943588729496695 0.988484259423288 GO:0008374 O-acyltransferase activity 2/1510 55/18639 0.0363636363636364 0.448862131246237 0.94413466365969 0.988484259423288 GO:0004620 phospholipase activity 5/1510 109/18639 0.0458715596330275 0.566225165562914 0.946785749697055 0.990365238175891 GO:0170055 lipid transmembrane transporter activity 2/1510 56/18639 0.0357142857142857 0.440846736045412 0.947897276805355 0.990633853757806 GO:0004033 aldo-keto reductase (NADPH) activity 1/1510 36/18639 0.0277777777777778 0.342880794701987 0.952374156487724 0.994415898530876 GO:0022829 wide pore channel activity 1/1510 37/18639 0.027027027027027 0.333613746196528 0.956239932099375 0.994814663251904 GO:0030280 structural constituent of skin epidermis 1/1510 37/18639 0.027027027027027 0.333613746196528 0.956239932099375 0.994814663251904 GO:0015293 symporter activity 7/1510 146/18639 0.0479452054794521 0.591821645650005 0.956717456632574 0.994814663251904 GO:0036002 pre-mRNA binding 2/1510 59/18639 0.0338983050847458 0.418430800314289 0.957787744457817 0.994814663251904 GO:0070888 E-box binding 2/1510 59/18639 0.0338983050847458 0.418430800314289 0.957787744457817 0.994814663251904 GO:0015085 calcium ion transmembrane transporter activity 7/1510 147/18639 0.0476190476190476 0.587795648060549 0.958731484371933 0.994814663251904 GO:0015081 sodium ion transmembrane transporter activity 8/1510 164/18639 0.0487804878048781 0.602132127281538 0.960375309223808 0.994814663251904 GO:0005179 hormone activity 6/1510 132/18639 0.0454545454545455 0.561077664057797 0.961561257040818 0.994814663251904 GO:0015103 inorganic anion transmembrane transporter activity 8/1510 165/18639 0.0484848484848485 0.59848284166165 0.962152793313331 0.994814663251904 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 9/1510 181/18639 0.0497237569060773 0.613775566206871 0.962237159470591 0.994814663251904 GO:0008509 monoatomic anion transmembrane transporter activity 7/1510 149/18639 0.0469798657718121 0.579905773589937 0.962507705474499 0.994814663251904 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/1510 39/18639 0.0256410256410256 0.31650534895568 0.963056127841792 0.994814663251904 GO:0015144 carbohydrate transmembrane transporter activity 1/1510 40/18639 0.025 0.308592715231788 0.966055334667539 0.99613712889651 GO:0071855 neuropeptide receptor binding 1/1510 40/18639 0.025 0.308592715231788 0.966055334667539 0.99613712889651 GO:0008227 G protein-coupled amine receptor activity 1/1510 41/18639 0.024390243902439 0.301066063640769 0.9688112056634 0.997340785174116 GO:0030165 PDZ domain binding 3/1510 83/18639 0.036144578313253 0.44615814250379 0.968943679125155 0.997340785174116 GO:0005253 monoatomic anion channel activity 4/1510 103/18639 0.0388349514563107 0.479367324631904 0.971697583113335 0.999287931524716 GO:0140303 intramembrane lipid transporter activity 1/1510 45/18639 0.0222222222222222 0.274304635761589 0.977772727601689 0.999999976489183 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/1510 46/18639 0.0217391304347826 0.268341491505903 0.979577781991355 0.999999976489183 GO:0099095 ligand-gated monoatomic anion channel activity 1/1510 47/18639 0.0212765957446809 0.262632098069607 0.981236338931765 0.999999976489183 GO:0140938 histone H3 methyltransferase activity 1/1510 47/18639 0.0212765957446809 0.262632098069607 0.981236338931765 0.999999976489183 GO:0016298 lipase activity 5/1510 130/18639 0.0384615384615385 0.47475802343352 0.983136872130346 0.999999976489183 GO:0005262 calcium channel activity 5/1510 131/18639 0.0381679389312977 0.471133916384409 0.98407211564378 0.999999976489183 GO:0016763 pentosyltransferase activity 1/1510 49/18639 0.0204081632653061 0.251912420597378 0.984160526989535 0.999999976489183 GO:0005272 sodium channel activity 1/1510 51/18639 0.0196078431372549 0.242033502142579 0.986629254701779 0.999999976489183 GO:0016597 amino acid binding 1/1510 51/18639 0.0196078431372549 0.242033502142579 0.986629254701779 0.999999976489183 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/1510 52/18639 0.0192307692307692 0.23737901171676 0.987715429943887 0.999999976489183 GO:0008146 sulfotransferase activity 1/1510 53/18639 0.0188679245283019 0.232900162439085 0.988713423207175 0.999999976489183 GO:0008528 G protein-coupled peptide receptor activity 4/1510 122/18639 0.0327868852459016 0.404711757681034 0.991095104650279 0.999999976489183 GO:0004497 monooxygenase activity 3/1510 106/18639 0.0283018867924528 0.349350243658628 0.993193263194535 0.999999976489183 GO:0001653 peptide receptor activity 4/1510 128/18639 0.03125 0.385740894039735 0.993901464226326 0.999999976489183 GO:0046873 metal ion transmembrane transporter activity 23/1510 450/18639 0.0511111111111111 0.630900662251656 0.995101243742074 0.999999976489183 GO:0003730 mRNA 3'-UTR binding 10/1510 262/18639 0.0381679389312977 0.471133916384409 0.998341979224239 0.999999976489183 GO:0099094 ligand-gated monoatomic cation channel activity 3/1510 136/18639 0.0220588235294118 0.272287689910401 0.999162195287887 0.999999976489183 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 9/1510 268/18639 0.0335820895522388 0.414527527923297 0.999558942397094 0.999999976489183 GO:0001217 DNA-binding transcription repressor activity 9/1510 278/18639 0.0323741007194245 0.399616465767783 0.999751271397758 0.999999976489183 GO:0005249 voltage-gated potassium channel activity 1/1510 98/18639 0.0102040816326531 0.125956210298689 0.999751959380739 0.999999976489183 GO:0005267 potassium channel activity 1/1510 124/18639 0.00806451612903226 0.0995460371715445 0.999972796230811 0.999999976489183 GO:0015276 ligand-gated monoatomic ion channel activity 3/1510 186/18639 0.0161290322580645 0.199092074343089 0.999978727798039 0.999999976489183 GO:0015079 potassium ion transmembrane transporter activity 2/1510 160/18639 0.0125 0.154296357615894 0.999980675132201 0.999999976489183 GO:0005261 monoatomic cation channel activity 10/1510 341/18639 0.0293255131964809 0.361985589714707 0.999980985171125 0.999999976489183 GO:0022834 ligand-gated channel activity 3/1510 188/18639 0.0159574468085106 0.196974073552205 0.999981697581611 0.999999976489183 GO:0005244 voltage-gated monoatomic ion channel activity 2/1510 173/18639 0.0115606936416185 0.142701833633197 0.999993133174015 0.999999976489183 GO:0022832 voltage-gated channel activity 2/1510 175/18639 0.0114285714285714 0.141070955534532 0.999994146811183 0.999999976489183 GO:0022843 voltage-gated monoatomic cation channel activity 1/1510 143/18639 0.00699300699300699 0.0863196406242764 0.999994601437402 0.999999976489183 GO:0045182 translation regulator activity 9/1510 356/18639 0.0252808988764045 0.312060049110797 0.999997878127975 0.999999976489183 GO:0005216 monoatomic ion channel activity 13/1510 448/18639 0.0290178571428571 0.358187973036897 0.999998913843165 0.999999976489183 GO:0022836 gated channel activity 5/1510 318/18639 0.0157232704402516 0.194083468699238 0.999999947026063 0.999999976489183 GO:0030371 translation repressor activity 5/1510 329/18639 0.0151975683890578 0.187594355764005 0.999999976489183 0.999999976489183