ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	19/285	175/18639	0.108571428571429	7.10057142857143	2.55439716652522e-11	1.52242071124903e-08
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	12/285	68/18639	0.176470588235294	11.5411764705882	4.40504003401413e-10	1.31270193013621e-07
GO:0022853	active monoatomic ion transmembrane transporter activity	14/285	118/18639	0.11864406779661	7.75932203389831	3.49526692561631e-09	6.94393029222441e-07
GO:0009055	electron transfer activity	13/285	116/18639	0.112068965517241	7.32931034482759	2.56614369864429e-08	3.18613868103812e-06
GO:0015078	proton transmembrane transporter activity	16/285	185/18639	0.0864864864864865	5.65621621621622	2.6729351350991e-08	3.18613868103812e-06
GO:0015399	primary active transmembrane transporter activity	14/285	166/18639	0.0843373493975904	5.51566265060241	2.74132137938445e-07	2.72304590352188e-05
GO:0042605	peptide antigen binding	8/285	45/18639	0.177777777777778	11.6266666666667	3.57470524765115e-07	3.04360618228584e-05
GO:0023023	MHC protein complex binding	7/285	37/18639	0.189189189189189	12.372972972973	1.26195779496748e-06	9.40158557250772e-05
GO:0042277	peptide binding	16/285	249/18639	0.0642570281124498	4.20240963855422	1.54011779384527e-06	0.00010199002279242
GO:0005201	extracellular matrix structural constituent	13/285	168/18639	0.0773809523809524	5.06071428571429	1.94752326671012e-06	0.000116072386695923
GO:0008137	NADH dehydrogenase (ubiquinone) activity	7/285	41/18639	0.170731707317073	11.1658536585366	2.61533155917377e-06	0.000136053567215993
GO:0023026	MHC class II protein complex binding	6/285	27/18639	0.222222222222222	14.5333333333333	2.73933356810724e-06	0.000136053567215993
GO:0045296	cadherin binding	18/285	334/18639	0.0538922155688623	3.52455089820359	4.21552160171234e-06	0.000182484004797621
GO:0003954	NADH dehydrogenase activity	7/285	44/18639	0.159090909090909	10.4045454545455	4.28653702544746e-06	0.000182484004797621
GO:0050840	extracellular matrix binding	8/285	67/18639	0.119402985074627	7.8089552238806	8.08654779650477e-06	0.000321305499114456
GO:0042608	T cell receptor binding	4/285	11/18639	0.363636363636364	23.7818181818182	1.62299726372919e-05	0.000604566480739124
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	7/285	58/18639	0.120689655172414	7.89310344827586	2.80206197181151e-05	0.000982369961882152
GO:0005178	integrin binding	11/285	161/18639	0.0683229813664596	4.46832298136646	3.86107902879875e-05	0.00124222916657178
GO:0008135	translation factor activity, RNA binding	8/285	83/18639	0.0963855421686747	6.30361445783133	3.96012653772882e-05	0.00124222916657178
GO:0180051	translation factor activity	8/285	84/18639	0.0952380952380952	6.22857142857143	4.31972171865563e-05	0.00128727707215938
GO:0004129	cytochrome-c oxidase activity	4/285	15/18639	0.266666666666667	17.44	6.39642961419926e-05	0.00181536764288703
GO:0008201	heparin binding	11/285	172/18639	0.063953488372093	4.18255813953488	7.04902294834463e-05	0.00190964439873336
GO:0001968	fibronectin binding	5/285	30/18639	0.166666666666667	10.9	8.40582694166573e-05	0.00209251214865228
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/285	16/18639	0.25	16.35	8.42622341739175e-05	0.00209251214865228
GO:0097110	scaffold protein binding	7/285	70/18639	0.1	6.54	9.55705703210999e-05	0.00227840239645502
GO:0005125	cytokine activity	12/285	234/18639	0.0512820512820513	3.35384615384615	0.000270174470543233	0.0061932301709141
GO:0003823	antigen binding	10/285	174/18639	0.0574712643678161	3.75862068965517	0.000355744589136306	0.00770454244184123
GO:0005539	glycosaminoglycan binding	12/285	242/18639	0.0495867768595041	3.24297520661157	0.000366661075475567	0.00770454244184123
GO:0019955	cytokine binding	9/285	144/18639	0.0625	4.0875	0.000378795044241812	0.00770454244184123
GO:0032395	MHC class II receptor activity	3/285	10/18639	0.3	19.62	0.000392021632339258	0.00770454244184123
GO:0016651	oxidoreductase activity, acting on NAD(P)H	7/285	88/18639	0.0795454545454545	5.20227272727273	0.000400739623652816	0.00770454244184123
GO:1990948	ubiquitin ligase inhibitor activity	3/285	11/18639	0.272727272727273	17.8363636363636	0.000532943504727494	0.00992607277554958
GO:0005518	collagen binding	6/285	72/18639	0.0833333333333333	5.45	0.000813415860996311	0.0146907834289031
GO:1901681	sulfur compound binding	12/285	275/18639	0.0436363636363636	2.85381818181818	0.00112868287617864	0.019785146888308
GO:0003779	actin binding	16/285	443/18639	0.036117381489842	2.36207674943567	0.00137224749383071	0.0226237081400701
GO:0140463	chromatin-protein adaptor activity	5/285	54/18639	0.0925925925925926	6.05555555555556	0.00138374508023179	0.0226237081400701
GO:0055105	ubiquitin-protein transferase inhibitor activity	3/285	15/18639	0.2	13.08	0.00140449194829294	0.0226237081400701
GO:0005200	structural constituent of cytoskeleton	7/285	112/18639	0.0625	4.0875	0.00167754742169815	0.0263110069297921
GO:0022804	active transmembrane transporter activity	16/285	457/18639	0.0350109409190372	2.28971553610503	0.00188278774912215	0.0287728589353026
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	3/285	18/18639	0.166666666666667	10.9	0.00243483748872099	0.0362790785819427
GO:0140375	immune receptor activity	8/285	156/18639	0.0512820512820513	3.35384615384615	0.00279897179345231	0.040687492412136
GO:0005126	cytokine receptor binding	11/285	275/18639	0.04	2.616	0.00351327091277038	0.0498549872383606
GO:0042056	chemoattractant activity	4/285	42/18639	0.0952380952380952	6.22857142857143	0.00379399297280291	0.0525865072509426
GO:0019838	growth factor binding	7/285	136/18639	0.0514705882352941	3.36617647058823	0.00496583168406784	0.0647165258881895
GO:0051015	actin filament binding	9/285	209/18639	0.0430622009569378	2.81626794258373	0.00498831831099548	0.0647165258881895
GO:0070577	lysine-acetylated histone binding	3/285	23/18639	0.130434782608696	8.5304347826087	0.00499489964908845	0.0647165258881895
GO:0050431	transforming growth factor beta binding	3/285	24/18639	0.125	8.175	0.00564463354801646	0.0700875332212044
GO:0140033	acetylation-dependent protein binding	3/285	24/18639	0.125	8.175	0.00564463354801646	0.0700875332212044
GO:0042974	nuclear retinoic acid receptor binding	3/285	25/18639	0.12	7.848	0.00634269649250678	0.0771479001945723
GO:0003743	translation initiation factor activity	4/285	51/18639	0.0784313725490196	5.12941176470588	0.00761148440684365	0.0907288941295763
GO:0015252	proton channel activity	3/285	27/18639	0.111111111111111	7.26666666666667	0.00788724154117248	0.0921724697752706
GO:0016860	intramolecular oxidoreductase activity	4/285	53/18639	0.0754716981132075	4.93584905660377	0.00871004881699742	0.0998305595178935
GO:0004629	phospholipase C activity	3/285	29/18639	0.103448275862069	6.76551724137931	0.00963465930942075	0.104771005902525
GO:0051861	glycolipid binding	3/285	29/18639	0.103448275862069	6.76551724137931	0.00963465930942075	0.104771005902525
GO:0031720	haptoglobin binding	2/285	10/18639	0.2	13.08	0.00966846530979675	0.104771005902525
GO:0070325	lipoprotein particle receptor binding	3/285	31/18639	0.0967741935483871	6.32903225806452	0.0115899488725873	0.114300892374121
GO:0099106	ion channel regulator activity	7/285	160/18639	0.04375	2.86125	0.0116787697120771	0.114300892374121
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/285	11/18639	0.181818181818182	11.8909090909091	0.0116985812664788	0.114300892374121
GO:0048185	activin binding	2/285	11/18639	0.181818181818182	11.8909090909091	0.0116985812664788	0.114300892374121
GO:0050998	nitric-oxide synthase binding	2/285	11/18639	0.181818181818182	11.8909090909091	0.0116985812664788	0.114300892374121
GO:0097493	structural molecule activity conferring elasticity	2/285	11/18639	0.181818181818182	11.8909090909091	0.0116985812664788	0.114300892374121
GO:0015459	potassium channel regulator activity	4/285	59/18639	0.0677966101694915	4.43389830508475	0.0126107389232636	0.121225812875243
GO:0005078	MAP-kinase scaffold activity	2/285	12/18639	0.166666666666667	10.9	0.0138977827345841	0.128753912238118
GO:0097371	MDM2/MDM4 family protein binding	2/285	12/18639	0.166666666666667	10.9	0.0138977827345841	0.128753912238118
GO:0033218	amide binding	9/285	247/18639	0.0364372469635627	2.382995951417	0.0140419535159021	0.128753912238118
GO:0008376	acetylgalactosaminyltransferase activity	3/285	34/18639	0.0882352941176471	5.77058823529412	0.014921022333979	0.132900540295511
GO:0016247	channel regulator activity	7/285	168/18639	0.0416666666666667	2.725	0.0149401614090591	0.132900540295511
GO:0141108	transporter regulator activity	7/285	170/18639	0.0411764705882353	2.69294117647059	0.0158476413369289	0.137870532418559
GO:0004896	cytokine receptor activity	5/285	96/18639	0.0520833333333333	3.40625	0.015961521370605	0.137870532418559
GO:0055106	ubiquitin-protein transferase regulator activity	3/285	36/18639	0.0833333333333333	5.45	0.0174111805950511	0.146727543350737
GO:0019843	rRNA binding	4/285	65/18639	0.0615384615384615	4.02461538461538	0.0174792878823865	0.146727543350737
GO:0044325	transmembrane transporter binding	6/285	136/18639	0.0441176470588235	2.88529411764706	0.0182846807871528	0.149247465953753
GO:0005344	oxygen carrier activity	2/285	14/18639	0.142857142857143	9.34285714285714	0.018781140849885	0.149247465953753
GO:0008191	metalloendopeptidase inhibitor activity	2/285	14/18639	0.142857142857143	9.34285714285714	0.018781140849885	0.149247465953753
GO:0044548	S100 protein binding	2/285	14/18639	0.142857142857143	9.34285714285714	0.018781140849885	0.149247465953753
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/285	15/18639	0.133333333333333	8.72	0.0214544714501299	0.168248223477334
GO:0061134	peptidase regulator activity	8/285	226/18639	0.0353982300884956	2.31504424778761	0.023295527363581	0.180313432580445
GO:0005024	transforming growth factor beta receptor activity	2/285	16/18639	0.125	8.175	0.0242752301795972	0.183197738276248
GO:0017080	sodium channel regulator activity	3/285	41/18639	0.0731707317073171	4.78536585365854	0.0245903004397648	0.183197738276248
GO:0042287	MHC protein binding	3/285	41/18639	0.0731707317073171	4.78536585365854	0.0245903004397648	0.183197738276248
GO:0008307	structural constituent of muscle	3/285	42/18639	0.0714285714285714	4.67142857142857	0.0261900163987619	0.188767870154406
GO:0035198	miRNA binding	3/285	42/18639	0.0714285714285714	4.67142857142857	0.0261900163987619	0.188767870154406
GO:0004857	enzyme inhibitor activity	12/285	416/18639	0.0288461538461538	1.88653846153846	0.0269385719918602	0.188767870154406
GO:0038191	neuropilin binding	2/285	17/18639	0.117647058823529	7.69411764705882	0.0272383168343606	0.188767870154406
GO:0048038	quinone binding	2/285	17/18639	0.117647058823529	7.69411764705882	0.0272383168343606	0.188767870154406
GO:1990226	histone methyltransferase binding	2/285	17/18639	0.117647058823529	7.69411764705882	0.0272383168343606	0.188767870154406
GO:0044183	protein folding chaperone	4/285	75/18639	0.0533333333333333	3.488	0.027907235471302	0.191180601619494
GO:0030246	carbohydrate binding	9/285	280/18639	0.0321428571428571	2.10214285714286	0.0288080246222032	0.195108894032194
GO:0030547	signaling receptor inhibitor activity	3/285	44/18639	0.0681818181818182	4.45909090909091	0.0295528636436537	0.197904570018176
GO:0003746	translation elongation factor activity	2/285	18/18639	0.111111111111111	7.26666666666667	0.0303387517525656	0.198702154335484
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/285	18/18639	0.111111111111111	7.26666666666667	0.0303387517525656	0.198702154335484
GO:0008009	chemokine activity	3/285	45/18639	0.0666666666666667	4.36	0.031315696670284	0.201795502841418
GO:0019199	transmembrane receptor protein kinase activity	4/285	78/18639	0.0512820512820513	3.35384615384615	0.0316233834622851	0.201795502841418
GO:0001221	transcription coregulator binding	5/285	115/18639	0.0434782608695652	2.84347826086956	0.031826807495123	0.201795502841418
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/285	19/18639	0.105263157894737	6.88421052631579	0.0335716733418552	0.206275436203564
GO:0030506	ankyrin binding	2/285	19/18639	0.105263157894737	6.88421052631579	0.0335716733418552	0.206275436203564
GO:0034987	immunoglobulin receptor binding	2/285	19/18639	0.105263157894737	6.88421052631579	0.0335716733418552	0.206275436203564
GO:0061749	forked DNA-dependent helicase activity	3/285	47/18639	0.0638297872340425	4.17446808510638	0.0350031645452748	0.210726121908927
GO:1990518	single-stranded 3'-5' DNA helicase activity	3/285	47/18639	0.0638297872340425	4.17446808510638	0.0350031645452748	0.210726121908927
GO:0009378	four-way junction helicase activity	3/285	48/18639	0.0625	4.0875	0.0369272905800103	0.21165069278527
GO:0036121	double-stranded DNA helicase activity	3/285	48/18639	0.0625	4.0875	0.0369272905800103	0.21165069278527
GO:0043138	3'-5' DNA helicase activity	3/285	48/18639	0.0625	4.0875	0.0369272905800103	0.21165069278527
GO:0016004	phospholipase activator activity	2/285	20/18639	0.1	6.54	0.0369323356538056	0.21165069278527
GO:0042288	MHC class I protein binding	2/285	20/18639	0.1	6.54	0.0369323356538056	0.21165069278527
GO:0004866	endopeptidase inhibitor activity	6/285	161/18639	0.0372670807453416	2.43726708074534	0.037567477433564	0.213240157622897
GO:0051082	unfolded protein binding	5/285	121/18639	0.0413223140495868	2.70247933884298	0.0383457800432973	0.214077713928413
GO:0001540	amyloid-beta binding	4/285	83/18639	0.0481927710843374	3.15180722891566	0.0384334150844634	0.214077713928413
GO:0005516	calmodulin binding	7/285	207/18639	0.0338164251207729	2.21159420289855	0.0403308217726379	0.222566386819372
GO:0008081	phosphoric diester hydrolase activity	4/285	87/18639	0.0459770114942529	3.00689655172414	0.0444394446270628	0.242989990804857
GO:0005080	protein kinase C binding	3/285	52/18639	0.0576923076923077	3.77307692307692	0.0451523561237085	0.244643674997548
GO:0030414	peptidase inhibitor activity	6/285	169/18639	0.0355029585798817	2.32189349112426	0.0457421781142134	0.245606650054696
GO:0051018	protein kinase A binding	3/285	53/18639	0.0566037735849057	3.70188679245283	0.0473388945621112	0.251910546062663
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3/285	54/18639	0.0555555555555556	3.63333333333333	0.0495767028824743	0.261484202813758
GO:0140030	modification-dependent protein binding	6/285	173/18639	0.0346820809248555	2.26820809248555	0.0502138535986745	0.26252155039307
GO:0048027	mRNA 5'-UTR binding	2/285	24/18639	0.0833333333333333	5.45	0.0515613887129902	0.264202823253216
GO:0060229	lipase activator activity	2/285	24/18639	0.0833333333333333	5.45	0.0515613887129902	0.264202823253216
GO:0140313	molecular sequestering activity	3/285	55/18639	0.0545454545454545	3.56727272727273	0.0518653193299099	0.264202823253216
GO:0015662	P-type ion transporter activity	2/285	25/18639	0.08	5.232	0.0554934489060757	0.277933576033791
GO:0140358	P-type transmembrane transporter activity	2/285	25/18639	0.08	5.232	0.0554934489060757	0.277933576033791
GO:0004601	peroxidase activity	3/285	57/18639	0.0526315789473684	3.44210526315789	0.0565930195359506	0.279355395513279
GO:0002020	protease binding	5/285	136/18639	0.0367647058823529	2.40441176470588	0.0579885040240045	0.279355395513279
GO:0016853	isomerase activity	6/285	180/18639	0.0333333333333333	2.18	0.0586646822612199	0.279355395513279
GO:0017116	single-stranded DNA helicase activity	3/285	58/18639	0.0517241379310345	3.38275862068966	0.0590310731420033	0.279355395513279
GO:0061980	regulatory RNA binding	3/285	58/18639	0.0517241379310345	3.38275862068966	0.0590310731420033	0.279355395513279
GO:0004435	phosphatidylinositol phospholipase C activity	2/285	26/18639	0.0769230769230769	5.03076923076923	0.0595270725338699	0.279355395513279
GO:0030247	polysaccharide binding	2/285	26/18639	0.0769230769230769	5.03076923076923	0.0595270725338699	0.279355395513279
GO:0050750	low-density lipoprotein particle receptor binding	2/285	26/18639	0.0769230769230769	5.03076923076923	0.0595270725338699	0.279355395513279
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	3/285	59/18639	0.0508474576271186	3.32542372881356	0.0615178767608643	0.286442613667775
GO:0008237	metallopeptidase activity	6/285	184/18639	0.0326086956521739	2.13260869565217	0.0638532924840163	0.292742787080567
GO:0061135	endopeptidase regulator activity	6/285	184/18639	0.0326086956521739	2.13260869565217	0.0638532924840163	0.292742787080567
GO:0045499	chemorepellent activity	2/285	28/18639	0.0714285714285714	4.67142857142857	0.0678831055938473	0.306654250877873
GO:0031406	carboxylic acid binding	6/285	187/18639	0.0320855614973262	2.09839572192513	0.0679167132816765	0.306654250877873
GO:0019903	protein phosphatase binding	5/285	144/18639	0.0347222222222222	2.27083333333333	0.0704370951340651	0.314490018262851
GO:0043177	organic acid binding	6/285	189/18639	0.0317460317460317	2.07619047619048	0.0707074873275537	0.314490018262851
GO:0008238	exopeptidase activity	4/285	102/18639	0.0392156862745098	2.56470588235294	0.07134263244219	0.314964510633668
GO:0048019	receptor antagonist activity	2/285	30/18639	0.0666666666666667	4.36	0.0765986450242718	0.33568229731225
GO:0042393	histone binding	7/285	247/18639	0.0283400809716599	1.85344129554656	0.0857801686566465	0.37224303318
GO:0004620	phospholipase activity	4/285	109/18639	0.036697247706422	2.4	0.0861905009712081	0.37224303318
GO:0004222	metalloendopeptidase activity	4/285	110/18639	0.0363636363636364	2.37818181818182	0.0884255070541797	0.377198615713682
GO:0140104	molecular carrier activity	7/285	249/18639	0.0281124497991968	1.83855421686747	0.0886037016777106	0.377198615713682
GO:0030296	protein tyrosine kinase activator activity	2/285	33/18639	0.0606060606060606	3.96363636363636	0.0902822383687634	0.378931084984387
GO:0140311	protein sequestering activity	2/285	33/18639	0.0606060606060606	3.96363636363636	0.0902822383687634	0.378931084984387
GO:0043022	ribosome binding	4/285	112/18639	0.0357142857142857	2.33571428571429	0.0929787408435195	0.387519787012151
GO:0015035	protein-disulfide reductase activity	2/285	34/18639	0.0588235294117647	3.84705882352941	0.0949923143709374	0.390451168035026
GO:0019825	oxygen binding	2/285	34/18639	0.0588235294117647	3.84705882352941	0.0949923143709374	0.390451168035026
GO:0042379	chemokine receptor binding	3/285	72/18639	0.0416666666666667	2.725	0.0980067492754863	0.400082346357465
GO:0008083	growth factor activity	5/285	162/18639	0.0308641975308642	2.01851851851852	0.1033447818372	0.410204909708676
GO:0003678	DNA helicase activity	3/285	74/18639	0.0405405405405405	2.65135135135135	0.104253506264208	0.410204909708676
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/285	36/18639	0.0555555555555556	3.63333333333333	0.104616017241139	0.410204909708676
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	2/285	36/18639	0.0555555555555556	3.63333333333333	0.104616017241139	0.410204909708676
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	2/285	36/18639	0.0555555555555556	3.63333333333333	0.104616017241139	0.410204909708676
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	2/285	36/18639	0.0555555555555556	3.63333333333333	0.104616017241139	0.410204909708676
GO:0043394	proteoglycan binding	2/285	37/18639	0.0540540540540541	3.53513513513514	0.109523344346157	0.426639955753656
GO:0042162	telomeric DNA binding	2/285	38/18639	0.0526315789473684	3.44210526315789	0.114490255063287	0.442143684525759
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/285	39/18639	0.0512820512820513	3.35384615384615	0.11951379648815	0.442143684525759
GO:0033293	monocarboxylic acid binding	3/285	79/18639	0.0379746835443038	2.48354430379747	0.120526683595653	0.442143684525759
GO:0015036	disulfide oxidoreductase activity	2/285	40/18639	0.05	3.27	0.124591091512046	0.442143684525759
GO:0071949	FAD binding	2/285	40/18639	0.05	3.27	0.124591091512046	0.442143684525759
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	2/285	41/18639	0.0487804878048781	3.19024390243902	0.12971933720806	0.442143684525759
GO:0042826	histone deacetylase binding	4/285	127/18639	0.031496062992126	2.05984251968504	0.130468062087556	0.442143684525759
GO:0016859	cis-trans isomerase activity	2/285	42/18639	0.0476190476190476	3.11428571428571	0.134895803248525	0.442143684525759
GO:0043021	ribonucleoprotein complex binding	5/285	177/18639	0.0282485875706215	1.84745762711864	0.135620082669995	0.442143684525759
GO:0035591	signaling adaptor activity	4/285	129/18639	0.0310077519379845	2.02790697674419	0.135881524850668	0.442143684525759
GO:0016298	lipase activity	4/285	130/18639	0.0307692307692308	2.01230769230769	0.138622122450511	0.442143684525759
GO:0031072	heat shock protein binding	4/285	131/18639	0.0305343511450382	1.9969465648855	0.141384868514669	0.442143684525759
GO:0003796	lysozyme activity	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0004955	prostaglandin receptor activity	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0005031	tumor necrosis factor receptor activity	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0005528	FK506 binding	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0015203	polyamine transmembrane transporter activity	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0035374	chondroitin sulfate binding	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0042975	peroxisome proliferator activated receptor binding	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0043208	glycosphingolipid binding	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0050815	phosphoserine residue binding	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0051880	G-quadruplex DNA binding	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0070097	delta-catenin binding	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0099122	RNA polymerase II C-terminal domain binding	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0140940	histone H2A methyltransferase activity	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:1990259	histone H2AQ104 methyltransferase activity	1/285	10/18639	0.1	6.54	0.142834064454268	0.442143684525759
GO:0005179	hormone activity	4/285	132/18639	0.0303030303030303	1.98181818181818	0.144169437602611	0.442143684525759
GO:0016209	antioxidant activity	3/285	86/18639	0.0348837209302326	2.28139534883721	0.144739073668429	0.442143684525759
GO:0001223	transcription coactivator binding	2/285	44/18639	0.0454545454545455	2.97272727272727	0.145382828767998	0.442143684525759
GO:0051087	protein-folding chaperone binding	4/285	134/18639	0.0298507462686567	1.95223880597015	0.149802729482603	0.442143684525759
GO:0004197	cysteine-type endopeptidase activity	3/285	88/18639	0.0340909090909091	2.22954545454545	0.151931886882816	0.442143684525759
GO:0002162	dystroglycan binding	1/285	11/18639	0.0909090909090909	5.94545454545455	0.155947612773047	0.442143684525759
GO:0003953	NAD+ nucleosidase activity	1/285	11/18639	0.0909090909090909	5.94545454545455	0.155947612773047	0.442143684525759
GO:0004954	prostanoid receptor activity	1/285	11/18639	0.0909090909090909	5.94545454545455	0.155947612773047	0.442143684525759
GO:0005114	type II transforming growth factor beta receptor binding	1/285	11/18639	0.0909090909090909	5.94545454545455	0.155947612773047	0.442143684525759
GO:0008199	ferric iron binding	1/285	11/18639	0.0909090909090909	5.94545454545455	0.155947612773047	0.442143684525759
GO:0019107	myristoyltransferase activity	1/285	11/18639	0.0909090909090909	5.94545454545455	0.155947612773047	0.442143684525759
GO:0140031	phosphorylation-dependent protein binding	1/285	11/18639	0.0909090909090909	5.94545454545455	0.155947612773047	0.442143684525759
GO:0004180	carboxypeptidase activity	2/285	46/18639	0.0434782608695652	2.84347826086956	0.156031719217936	0.442143684525759
GO:0016922	nuclear receptor binding	4/285	137/18639	0.0291970802919708	1.90948905109489	0.158408054027393	0.442143684525759
GO:0005504	fatty acid binding	2/285	47/18639	0.0425531914893617	2.78297872340426	0.161410766092277	0.442143684525759
GO:0140597	protein carrier chaperone	5/285	188/18639	0.0265957446808511	1.73936170212766	0.161793734784314	0.442143684525759
GO:0019902	phosphatase binding	5/285	190/18639	0.0263157894736842	1.72105263157895	0.166759215767236	0.442143684525759
GO:0005025	transforming growth factor beta receptor activity, type I	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0005026	transforming growth factor beta receptor activity, type II	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0005095	GTPase inhibitor activity	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0005527	macrolide binding	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0008179	adenylate cyclase binding	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0015166	polyol transmembrane transporter activity	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0016273	arginine N-methyltransferase activity	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0016274	protein-arginine N-methyltransferase activity	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0016361	activin receptor activity, type I	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0016362	activin receptor activity, type II	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0017002	activin receptor activity	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0017166	vinculin binding	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0035259	nuclear glucocorticoid receptor binding	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0036009	protein-glutamine N-methyltransferase activity	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0045295	gamma-catenin binding	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0070008	serine-type exopeptidase activity	1/285	12/18639	0.0833333333333333	5.45	0.168861233685635	0.442143684525759
GO:0001664	G protein-coupled receptor binding	7/285	297/18639	0.0235690235690236	1.54141414141414	0.17126135913786	0.442143684525759
GO:0005004	GPI-linked ephrin receptor activity	2/285	49/18639	0.0408163265306122	2.66938775510204	0.172266430355995	0.442143684525759
GO:0005008	hepatocyte growth factor receptor activity	2/285	49/18639	0.0408163265306122	2.66938775510204	0.172266430355995	0.442143684525759
GO:0005009	insulin receptor activity	2/285	49/18639	0.0408163265306122	2.66938775510204	0.172266430355995	0.442143684525759
GO:0005011	macrophage colony-stimulating factor receptor activity	2/285	49/18639	0.0408163265306122	2.66938775510204	0.172266430355995	0.442143684525759
GO:0005018	platelet-derived growth factor alpha-receptor activity	2/285	49/18639	0.0408163265306122	2.66938775510204	0.172266430355995	0.442143684525759
GO:0005020	stem cell factor receptor activity	2/285	49/18639	0.0408163265306122	2.66938775510204	0.172266430355995	0.442143684525759
GO:0008288	boss receptor activity	2/285	49/18639	0.0408163265306122	2.66938775510204	0.172266430355995	0.442143684525759
GO:0036332	placental growth factor receptor activity	2/285	49/18639	0.0408163265306122	2.66938775510204	0.172266430355995	0.442143684525759
GO:0038062	protein tyrosine kinase collagen receptor activity	2/285	49/18639	0.0408163265306122	2.66938775510204	0.172266430355995	0.442143684525759
GO:0060175	brain-derived neurotrophic factor receptor activity	2/285	49/18639	0.0408163265306122	2.66938775510204	0.172266430355995	0.442143684525759
GO:0005006	epidermal growth factor receptor activity	2/285	50/18639	0.04	2.616	0.177738580888499	0.442143684525759
GO:0005007	fibroblast growth factor receptor activity	2/285	50/18639	0.04	2.616	0.177738580888499	0.442143684525759
GO:0005017	platelet-derived growth factor receptor activity	2/285	50/18639	0.04	2.616	0.177738580888499	0.442143684525759
GO:0005019	platelet-derived growth factor beta-receptor activity	2/285	50/18639	0.04	2.616	0.177738580888499	0.442143684525759
GO:0048020	CCR chemokine receptor binding	2/285	50/18639	0.04	2.616	0.177738580888499	0.442143684525759
GO:0004867	serine-type endopeptidase inhibitor activity	3/285	95/18639	0.0315789473684211	2.06526315789474	0.177943565779197	0.442143684525759
GO:0031625	ubiquitin protein ligase binding	7/285	302/18639	0.0231788079470199	1.5158940397351	0.18137096687559	0.442143684525759
GO:0005035	death receptor activity	1/285	13/18639	0.0769230769230769	5.03076923076923	0.181577964688995	0.442143684525759
GO:0005172	vascular endothelial growth factor receptor binding	1/285	13/18639	0.0769230769230769	5.03076923076923	0.181577964688995	0.442143684525759
GO:0008035	high-density lipoprotein particle binding	1/285	13/18639	0.0769230769230769	5.03076923076923	0.181577964688995	0.442143684525759
GO:0017154	semaphorin receptor activity	1/285	13/18639	0.0769230769230769	5.03076923076923	0.181577964688995	0.442143684525759
GO:0019855	calcium channel inhibitor activity	1/285	13/18639	0.0769230769230769	5.03076923076923	0.181577964688995	0.442143684525759
GO:0043560	insulin receptor substrate binding	1/285	13/18639	0.0769230769230769	5.03076923076923	0.181577964688995	0.442143684525759
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/285	13/18639	0.0769230769230769	5.03076923076923	0.181577964688995	0.442143684525759
GO:0070123	transforming growth factor beta receptor activity, type III	1/285	13/18639	0.0769230769230769	5.03076923076923	0.181577964688995	0.442143684525759
GO:0071837	HMG box domain binding	1/285	13/18639	0.0769230769230769	5.03076923076923	0.181577964688995	0.442143684525759
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/285	13/18639	0.0769230769230769	5.03076923076923	0.181577964688995	0.442143684525759
GO:0005010	insulin-like growth factor receptor activity	2/285	51/18639	0.0392156862745098	2.56470588235294	0.183237399459501	0.442143684525759
GO:0005021	vascular endothelial growth factor receptor activity	2/285	51/18639	0.0392156862745098	2.56470588235294	0.183237399459501	0.442143684525759
GO:0005030	neurotrophin receptor activity	2/285	51/18639	0.0392156862745098	2.56470588235294	0.183237399459501	0.442143684525759
GO:0005161	platelet-derived growth factor receptor binding	1/285	14/18639	0.0714285714285714	4.67142857142857	0.194100797292004	0.447188409932496
GO:0008494	translation activator activity	1/285	14/18639	0.0714285714285714	4.67142857142857	0.194100797292004	0.447188409932496
GO:0019992	diacylglycerol binding	1/285	14/18639	0.0714285714285714	4.67142857142857	0.194100797292004	0.447188409932496
GO:0031404	chloride ion binding	1/285	14/18639	0.0714285714285714	4.67142857142857	0.194100797292004	0.447188409932496
GO:0032036	myosin heavy chain binding	1/285	14/18639	0.0714285714285714	4.67142857142857	0.194100797292004	0.447188409932496
GO:0061783	peptidoglycan muralytic activity	1/285	14/18639	0.0714285714285714	4.67142857142857	0.194100797292004	0.447188409932496
GO:0098821	BMP receptor activity	1/285	14/18639	0.0714285714285714	4.67142857142857	0.194100797292004	0.447188409932496
GO:0005003	ephrin receptor activity	2/285	53/18639	0.0377358490566038	2.46792452830189	0.19430675831571	0.447188409932496
GO:0005005	transmembrane-ephrin receptor activity	2/285	53/18639	0.0377358490566038	2.46792452830189	0.19430675831571	0.447188409932496
GO:0017046	peptide hormone binding	2/285	53/18639	0.0377358490566038	2.46792452830189	0.19430675831571	0.447188409932496
GO:0038064	collagen receptor activity	2/285	53/18639	0.0377358490566038	2.46792452830189	0.19430675831571	0.447188409932496
GO:0015485	cholesterol binding	2/285	54/18639	0.037037037037037	2.42222222222222	0.199873298909296	0.447188409932496
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	2/285	54/18639	0.037037037037037	2.42222222222222	0.199873298909296	0.447188409932496
GO:0051287	NAD binding	2/285	54/18639	0.037037037037037	2.42222222222222	0.199873298909296	0.447188409932496
GO:0000510	H3-H4 histone complex chaperone activity	4/285	151/18639	0.0264900662251656	1.73245033112583	0.200773607471178	0.447188409932496
GO:0140584	chromatin extrusion motor activity	4/285	151/18639	0.0264900662251656	1.73245033112583	0.200773607471178	0.447188409932496
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	4/285	151/18639	0.0264900662251656	1.73245033112583	0.200773607471178	0.447188409932496
GO:0140849	ATP-dependent H2AZ histone chaperone activity	4/285	151/18639	0.0264900662251656	1.73245033112583	0.200773607471178	0.447188409932496
GO:0015616	DNA translocase activity	4/285	152/18639	0.0263157894736842	1.72105263157895	0.203923140330667	0.447188409932496
GO:0140674	ATP-dependent histone chaperone activity	4/285	152/18639	0.0263157894736842	1.72105263157895	0.203923140330667	0.447188409932496
GO:0098632	cell-cell adhesion mediator activity	2/285	55/18639	0.0363636363636364	2.37818181818182	0.205458505685876	0.447188409932496
GO:0000774	adenyl-nucleotide exchange factor activity	1/285	15/18639	0.0666666666666667	4.36	0.206432677709281	0.447188409932496
GO:0004953	icosanoid receptor activity	1/285	15/18639	0.0666666666666667	4.36	0.206432677709281	0.447188409932496
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/285	15/18639	0.0666666666666667	4.36	0.206432677709281	0.447188409932496
GO:0005523	tropomyosin binding	1/285	15/18639	0.0666666666666667	4.36	0.206432677709281	0.447188409932496
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/285	15/18639	0.0666666666666667	4.36	0.206432677709281	0.447188409932496
GO:0033130	acetylcholine receptor binding	1/285	15/18639	0.0666666666666667	4.36	0.206432677709281	0.447188409932496
GO:0045504	dynein heavy chain binding	1/285	15/18639	0.0666666666666667	4.36	0.206432677709281	0.447188409932496
GO:0061775	cohesin loader activity	4/285	153/18639	0.0261437908496732	1.70980392156863	0.207087250237196	0.447188409932496
GO:0004386	helicase activity	4/285	155/18639	0.0258064516129032	1.68774193548387	0.213457787562034	0.458702811607667
GO:0140297	DNA-binding transcription factor binding	10/285	488/18639	0.0204918032786885	1.34016393442623	0.215514318846972	0.458702811607667
GO:0016504	peptidase activator activity	2/285	57/18639	0.0350877192982456	2.29473684210526	0.216677514616062	0.458702811607667
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/285	16/18639	0.0625	4.0875	0.218576507544593	0.458702811607667
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/285	16/18639	0.0625	4.0875	0.218576507544593	0.458702811607667
GO:0022841	potassium ion leak channel activity	1/285	16/18639	0.0625	4.0875	0.218576507544593	0.458702811607667
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/285	16/18639	0.0625	4.0875	0.218576507544593	0.458702811607667
GO:0070411	I-SMAD binding	1/285	16/18639	0.0625	4.0875	0.218576507544593	0.458702811607667
GO:0140658	ATP-dependent chromatin remodeler activity	4/285	158/18639	0.0253164556962025	1.65569620253165	0.223114092198232	0.459528247827871
GO:0044389	ubiquitin-like protein ligase binding	7/285	322/18639	0.0217391304347826	1.42173913043478	0.224140448194437	0.459528247827871
GO:0001786	phosphatidylserine binding	2/285	59/18639	0.0338983050847458	2.21694915254237	0.22794949441986	0.459528247827871
GO:0045309	protein phosphorylated amino acid binding	2/285	59/18639	0.0338983050847458	2.21694915254237	0.22794949441986	0.459528247827871
GO:0070888	E-box binding	2/285	59/18639	0.0338983050847458	2.21694915254237	0.22794949441986	0.459528247827871
GO:0003689	DNA clamp loader activity	4/285	160/18639	0.025	1.635	0.229614518848314	0.459528247827871
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/285	17/18639	0.0588235294117647	3.84705882352941	0.230535144463982	0.459528247827871
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/285	17/18639	0.0588235294117647	3.84705882352941	0.230535144463982	0.459528247827871
GO:0016018	cyclosporin A binding	1/285	17/18639	0.0588235294117647	3.84705882352941	0.230535144463982	0.459528247827871
GO:0019198	transmembrane receptor protein phosphatase activity	1/285	17/18639	0.0588235294117647	3.84705882352941	0.230535144463982	0.459528247827871
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/285	17/18639	0.0588235294117647	3.84705882352941	0.230535144463982	0.459528247827871
GO:0030548	acetylcholine receptor regulator activity	1/285	17/18639	0.0588235294117647	3.84705882352941	0.230535144463982	0.459528247827871
GO:0046965	nuclear retinoid X receptor binding	1/285	17/18639	0.0588235294117647	3.84705882352941	0.230535144463982	0.459528247827871
GO:0051787	misfolded protein binding	1/285	17/18639	0.0588235294117647	3.84705882352941	0.230535144463982	0.459528247827871
GO:0070403	NAD+ binding	1/285	17/18639	0.0588235294117647	3.84705882352941	0.230535144463982	0.459528247827871
GO:0005543	phospholipid binding	10/285	497/18639	0.0201207243460765	1.3158953722334	0.231550342385825	0.460013346873171
GO:0004714	transmembrane receptor protein tyrosine kinase activity	2/285	60/18639	0.0333333333333333	2.18	0.233601102207816	0.462545704039397
GO:0000400	four-way junction DNA binding	1/285	18/18639	0.0555555555555556	3.63333333333333	0.242311402858772	0.468223952103665
GO:0000900	mRNA regulatory element binding translation repressor activity	1/285	18/18639	0.0555555555555556	3.63333333333333	0.242311402858772	0.468223952103665
GO:0008409	5'-3' exonuclease activity	1/285	18/18639	0.0555555555555556	3.63333333333333	0.242311402858772	0.468223952103665
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/285	18/18639	0.0555555555555556	3.63333333333333	0.242311402858772	0.468223952103665
GO:0035615	clathrin adaptor activity	1/285	18/18639	0.0555555555555556	3.63333333333333	0.242311402858772	0.468223952103665
GO:0098641	cadherin binding involved in cell-cell adhesion	1/285	18/18639	0.0555555555555556	3.63333333333333	0.242311402858772	0.468223952103665
GO:0099602	neurotransmitter receptor regulator activity	1/285	18/18639	0.0555555555555556	3.63333333333333	0.242311402858772	0.468223952103665
GO:0140713	histone chaperone activity	4/285	164/18639	0.024390243902439	1.59512195121951	0.242753693288645	0.468223952103665
GO:0005507	copper ion binding	2/285	63/18639	0.0317460317460317	2.07619047619048	0.250599167507218	0.475877988934483
GO:0016874	ligase activity	4/285	167/18639	0.0239520958083832	1.56646706586826	0.252718151104047	0.475877988934483
GO:0003756	protein disulfide isomerase activity	1/285	19/18639	0.0526315789473684	3.44210526315789	0.2539080544986	0.475877988934483
GO:0008301	DNA binding, bending	1/285	19/18639	0.0526315789473684	3.44210526315789	0.2539080544986	0.475877988934483
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/285	19/18639	0.0526315789473684	3.44210526315789	0.2539080544986	0.475877988934483
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/285	19/18639	0.0526315789473684	3.44210526315789	0.2539080544986	0.475877988934483
GO:0022840	leak channel activity	1/285	19/18639	0.0526315789473684	3.44210526315789	0.2539080544986	0.475877988934483
GO:0022842	narrow pore channel activity	1/285	19/18639	0.0526315789473684	3.44210526315789	0.2539080544986	0.475877988934483
GO:0097001	ceramide binding	1/285	19/18639	0.0526315789473684	3.44210526315789	0.2539080544986	0.475877988934483
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/285	20/18639	0.05	3.27	0.265327829174642	0.491103683813934
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/285	20/18639	0.05	3.27	0.265327829174642	0.491103683813934
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/285	20/18639	0.05	3.27	0.265327829174642	0.491103683813934
GO:0140939	histone H4 methyltransferase activity	1/285	20/18639	0.05	3.27	0.265327829174642	0.491103683813934
GO:0008235	metalloexopeptidase activity	2/285	66/18639	0.0303030303030303	1.98181818181818	0.267630602596636	0.4938323193424
GO:0016500	protein-hormone receptor activity	2/285	67/18639	0.0298507462686567	1.95223880597015	0.273308572185906	0.501026612579198
GO:0008373	sialyltransferase activity	1/285	21/18639	0.0476190476190476	3.11428571428571	0.276573415333148	0.501026612579198
GO:0036122	BMP binding	1/285	21/18639	0.0476190476190476	3.11428571428571	0.276573415333148	0.501026612579198
GO:0051010	microtubule plus-end binding	1/285	21/18639	0.0476190476190476	3.11428571428571	0.276573415333148	0.501026612579198
GO:0072542	protein phosphatase activator activity	1/285	21/18639	0.0476190476190476	3.11428571428571	0.276573415333148	0.501026612579198
GO:0140312	cargo adaptor activity	1/285	21/18639	0.0476190476190476	3.11428571428571	0.276573415333148	0.501026612579198
GO:0032934	sterol binding	2/285	68/18639	0.0294117647058824	1.92352941176471	0.278984739836309	0.503863348310424
GO:0004175	endopeptidase activity	8/285	405/18639	0.0197530864197531	1.29185185185185	0.28075544961779	0.505529450067078
GO:0003697	single-stranded DNA binding	3/285	121/18639	0.0247933884297521	1.62148760330579	0.282378550008856	0.50692052953397
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	7/285	349/18639	0.0200573065902579	1.31174785100287	0.286669579309162	0.507212682180119
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/285	22/18639	0.0454545454545455	2.97272727272727	0.287647460699463	0.507212682180119
GO:0033691	sialic acid binding	1/285	22/18639	0.0454545454545455	2.97272727272727	0.287647460699463	0.507212682180119
GO:0034062	5'-3' RNA polymerase activity	1/285	22/18639	0.0454545454545455	2.97272727272727	0.287647460699463	0.507212682180119
GO:0070034	telomerase RNA binding	1/285	22/18639	0.0454545454545455	2.97272727272727	0.287647460699463	0.507212682180119
GO:0097747	RNA polymerase activity	1/285	22/18639	0.0454545454545455	2.97272727272727	0.287647460699463	0.507212682180119
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/285	23/18639	0.0434782608695652	2.84347826086956	0.298552572892655	0.520284600713516
GO:0004602	glutathione peroxidase activity	1/285	23/18639	0.0434782608695652	2.84347826086956	0.298552572892655	0.520284600713516
GO:0005158	insulin receptor binding	1/285	23/18639	0.0434782608695652	2.84347826086956	0.298552572892655	0.520284600713516
GO:0005212	structural constituent of eye lens	1/285	23/18639	0.0434782608695652	2.84347826086956	0.298552572892655	0.520284600713516
GO:0016887	ATP hydrolysis activity	8/285	417/18639	0.0191846522781775	1.25467625899281	0.30745811777813	0.529157955422034
GO:0015149	hexose transmembrane transporter activity	1/285	24/18639	0.0416666666666667	2.725	0.309291320030901	0.529157955422034
GO:0015295	solute:proton symporter activity	1/285	24/18639	0.0416666666666667	2.725	0.309291320030901	0.529157955422034
GO:0030215	semaphorin receptor binding	1/285	24/18639	0.0416666666666667	2.725	0.309291320030901	0.529157955422034
GO:0055056	D-glucose transmembrane transporter activity	1/285	24/18639	0.0416666666666667	2.725	0.309291320030901	0.529157955422034
GO:0031490	chromatin DNA binding	3/285	128/18639	0.0234375	1.5328125	0.311586240838583	0.529157955422034
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	3/285	128/18639	0.0234375	1.5328125	0.311586240838583	0.529157955422034
GO:0035064	methylated histone binding	2/285	74/18639	0.027027027027027	1.76756756756757	0.312935561221556	0.529157955422034
GO:0003725	double-stranded RNA binding	2/285	75/18639	0.0266666666666667	1.744	0.318565724518569	0.529157955422034
GO:0001848	complement binding	1/285	25/18639	0.04	2.616	0.319866231327769	0.529157955422034
GO:0015271	outward rectifier potassium channel activity	1/285	25/18639	0.04	2.616	0.319866231327769	0.529157955422034
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/285	25/18639	0.04	2.616	0.319866231327769	0.529157955422034
GO:0019211	phosphatase activator activity	1/285	25/18639	0.04	2.616	0.319866231327769	0.529157955422034
GO:0120020	cholesterol transfer activity	1/285	25/18639	0.04	2.616	0.319866231327769	0.529157955422034
GO:0017022	myosin binding	2/285	76/18639	0.0263157894736842	1.72105263157895	0.324184981888582	0.529157955422034
GO:0098631	cell adhesion mediator activity	2/285	76/18639	0.0263157894736842	1.72105263157895	0.324184981888582	0.529157955422034
GO:0140034	methylation-dependent protein binding	2/285	76/18639	0.0263157894736842	1.72105263157895	0.324184981888582	0.529157955422034
GO:0003724	RNA helicase activity	2/285	77/18639	0.025974025974026	1.6987012987013	0.329792352736694	0.529157955422034
GO:0004529	DNA exonuclease activity	1/285	26/18639	0.0384615384615385	2.51538461538462	0.330279797679525	0.529157955422034
GO:0005112	Notch binding	1/285	26/18639	0.0384615384615385	2.51538461538462	0.330279797679525	0.529157955422034
GO:0005160	transforming growth factor beta receptor binding	1/285	26/18639	0.0384615384615385	2.51538461538462	0.330279797679525	0.529157955422034
GO:0008157	protein phosphatase 1 binding	1/285	26/18639	0.0384615384615385	2.51538461538462	0.330279797679525	0.529157955422034
GO:0008198	ferrous iron binding	1/285	26/18639	0.0384615384615385	2.51538461538462	0.330279797679525	0.529157955422034
GO:0015145	monosaccharide transmembrane transporter activity	1/285	26/18639	0.0384615384615385	2.51538461538462	0.330279797679525	0.529157955422034
GO:0030507	spectrin binding	1/285	26/18639	0.0384615384615385	2.51538461538462	0.330279797679525	0.529157955422034
GO:0034237	protein kinase A regulatory subunit binding	1/285	26/18639	0.0384615384615385	2.51538461538462	0.330279797679525	0.529157955422034
GO:0043548	phosphatidylinositol 3-kinase binding	1/285	26/18639	0.0384615384615385	2.51538461538462	0.330279797679525	0.529157955422034
GO:0050681	nuclear androgen receptor binding	1/285	26/18639	0.0384615384615385	2.51538461538462	0.330279797679525	0.529157955422034
GO:0052742	phosphatidylinositol kinase activity	1/285	26/18639	0.0384615384615385	2.51538461538462	0.330279797679525	0.529157955422034
GO:0070006	metalloaminopeptidase activity	1/285	26/18639	0.0384615384615385	2.51538461538462	0.330279797679525	0.529157955422034
GO:0004364	glutathione transferase activity	1/285	27/18639	0.037037037037037	2.42222222222222	0.340534472243611	0.540470035399799
GO:0035255	ionotropic glutamate receptor binding	1/285	27/18639	0.037037037037037	2.42222222222222	0.340534472243611	0.540470035399799
GO:0008186	ATP-dependent activity, acting on RNA	2/285	79/18639	0.0253164556962025	1.65569620253165	0.34096767333947	0.540470035399799
GO:0046332	SMAD binding	2/285	79/18639	0.0253164556962025	1.65569620253165	0.34096767333947	0.540470035399799
GO:0003712	transcription coregulator activity	9/285	495/18639	0.0181818181818182	1.18909090909091	0.346191187846493	0.546708697915609
GO:0005242	inward rectifier potassium channel activity	1/285	28/18639	0.0357142857142857	2.33571428571429	0.350632671008417	0.546708697915609
GO:0046625	sphingolipid binding	1/285	28/18639	0.0357142857142857	2.33571428571429	0.350632671008417	0.546708697915609
GO:0046966	nuclear thyroid hormone receptor binding	1/285	28/18639	0.0357142857142857	2.33571428571429	0.350632671008417	0.546708697915609
GO:0051119	sugar transmembrane transporter activity	1/285	28/18639	0.0357142857142857	2.33571428571429	0.350632671008417	0.546708697915609
GO:0097718	disordered domain specific binding	1/285	28/18639	0.0357142857142857	2.33571428571429	0.350632671008417	0.546708697915609
GO:0051020	GTPase binding	6/285	315/18639	0.019047619047619	1.24571428571429	0.35132454916389	0.546708697915609
GO:0003713	transcription coactivator activity	5/285	256/18639	0.01953125	1.27734375	0.354165547086486	0.549694442873817
GO:0030295	protein kinase activator activity	3/285	139/18639	0.0215827338129496	1.41151079136691	0.357585299413261	0.552126524482652
GO:0070851	growth factor receptor binding	3/285	139/18639	0.0215827338129496	1.41151079136691	0.357585299413261	0.552126524482652
GO:0004181	metallocarboxypeptidase activity	1/285	29/18639	0.0344827586206897	2.2551724137931	0.360576773354482	0.55387566216307
GO:0043236	laminin binding	1/285	29/18639	0.0344827586206897	2.2551724137931	0.360576773354482	0.55387566216307
GO:0005254	chloride channel activity	2/285	83/18639	0.0240963855421687	1.57590361445783	0.3631360263842	0.556372935025663
GO:0020037	heme binding	3/285	142/18639	0.0211267605633803	1.38169014084507	0.370080318585364	0.560253799679998
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/285	30/18639	0.0333333333333333	2.18	0.370369122607247	0.560253799679998
GO:0016769	transferase activity, transferring nitrogenous groups	1/285	30/18639	0.0333333333333333	2.18	0.370369122607247	0.560253799679998
GO:0031624	ubiquitin conjugating enzyme binding	1/285	30/18639	0.0333333333333333	2.18	0.370369122607247	0.560253799679998
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/285	30/18639	0.0333333333333333	2.18	0.370369122607247	0.560253799679998
GO:0050660	flavin adenine dinucleotide binding	2/285	86/18639	0.0232558139534884	1.52093023255814	0.379577415112709	0.570496644439738
GO:0003714	transcription corepressor activity	4/285	204/18639	0.0196078431372549	1.28235294117647	0.379797053790823	0.570496644439738
GO:0005164	tumor necrosis factor receptor binding	1/285	31/18639	0.032258064516129	2.10967741935484	0.380012026581504	0.570496644439738
GO:0008194	UDP-glycosyltransferase activity	3/285	145/18639	0.0206896551724138	1.35310344827586	0.382531278454271	0.572835783815944
GO:0016757	glycosyltransferase activity	5/285	267/18639	0.0187265917602996	1.2247191011236	0.387503191700729	0.576046212997787
GO:0031369	translation initiation factor binding	1/285	32/18639	0.03125	2.04375	0.389507758117631	0.576046212997787
GO:0071813	lipoprotein particle binding	1/285	32/18639	0.03125	2.04375	0.389507758117631	0.576046212997787
GO:0071814	protein-lipid complex binding	1/285	32/18639	0.03125	2.04375	0.389507758117631	0.576046212997787
GO:0120015	sterol transfer activity	1/285	32/18639	0.03125	2.04375	0.389507758117631	0.576046212997787
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	5/285	268/18639	0.0186567164179104	1.22014925373134	0.390532676341931	0.576132364108394
GO:0019209	kinase activator activity	3/285	148/18639	0.0202702702702703	1.32567567567568	0.394927244588414	0.581176883394307
GO:0071889	14-3-3 protein binding	1/285	33/18639	0.0303030303030303	1.98181818181818	0.398858555609784	0.585516500353279
GO:0008094	ATP-dependent activity, acting on DNA	4/285	210/18639	0.019047619047619	1.24571428571429	0.400536296107772	0.586534723538654
GO:0072341	modified amino acid binding	2/285	91/18639	0.021978021978022	1.43736263736264	0.406570774809841	0.593912210261434
GO:0015020	glucuronosyltransferase activity	1/285	34/18639	0.0294117647058824	1.92352941176471	0.408066623526112	0.594639871935362
GO:0046906	tetrapyrrole binding	3/285	152/18639	0.0197368421052632	1.29078947368421	0.411351863174649	0.597308667774378
GO:0043178	alcohol binding	2/285	92/18639	0.0217391304347826	1.42173913043478	0.411902453784009	0.597308667774378
GO:0008017	microtubule binding	5/285	276/18639	0.0181159420289855	1.18478260869565	0.414719238434767	0.599174561751659
GO:0003774	cytoskeletal motor activity	3/285	153/18639	0.0196078431372549	1.28235294117647	0.415437155433398	0.599174561751659
GO:0140566	histone reader activity	1/285	35/18639	0.0285714285714286	1.86857142857143	0.417134132921171	0.599174561751659
GO:0051219	phosphoprotein binding	2/285	93/18639	0.021505376344086	1.40645161290323	0.417210475045198	0.599174561751659
GO:0001217	DNA-binding transcription repressor activity	5/285	278/18639	0.0179856115107914	1.17625899280576	0.420746051045042	0.602799630824146
GO:0042562	hormone binding	2/285	94/18639	0.0212765957446809	1.39148936170213	0.422494314806297	0.60316788664275
GO:0000993	RNA polymerase II complex binding	1/285	36/18639	0.0277777777777778	1.81666666666667	0.4260632219406	0.60316788664275
GO:0004033	aldo-keto reductase (NADPH) activity	1/285	36/18639	0.0277777777777778	1.81666666666667	0.4260632219406	0.60316788664275
GO:0004190	aspartic-type endopeptidase activity	1/285	36/18639	0.0277777777777778	1.81666666666667	0.4260632219406	0.60316788664275
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/285	36/18639	0.0277777777777778	1.81666666666667	0.4260632219406	0.60316788664275
GO:0030280	structural constituent of skin epidermis	1/285	37/18639	0.027027027027027	1.76756756756757	0.434855996318224	0.612536599566639
GO:0070001	aspartic-type peptidase activity	1/285	37/18639	0.027027027027027	1.76756756756757	0.434855996318224	0.612536599566639
GO:0031267	small GTPase binding	5/285	283/18639	0.0176678445229682	1.15547703180212	0.435764292309152	0.612536599566639
GO:0042626	ATPase-coupled transmembrane transporter activity	2/285	98/18639	0.0204081632653061	1.33469387755102	0.44337812175805	0.617604345326939
GO:0000146	microfilament motor activity	1/285	38/18639	0.0263157894736842	1.72105263157895	0.443514529865654	0.617604345326939
GO:0005501	retinoid binding	1/285	38/18639	0.0263157894736842	1.72105263157895	0.443514529865654	0.617604345326939
GO:0019840	isoprenoid binding	1/285	38/18639	0.0263157894736842	1.72105263157895	0.443514529865654	0.617604345326939
GO:0019207	kinase regulator activity	5/285	287/18639	0.0174216027874564	1.13937282229965	0.447718563203072	0.622005276617788
GO:0000217	DNA secondary structure binding	1/285	39/18639	0.0256410256410256	1.67692307692308	0.452040864954536	0.625095952466134
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/285	39/18639	0.0256410256410256	1.67692307692308	0.452040864954536	0.625095952466134
GO:0004177	aminopeptidase activity	1/285	40/18639	0.025	1.635	0.460437012991523	0.627964438771048
GO:0015144	carbohydrate transmembrane transporter activity	1/285	40/18639	0.025	1.635	0.460437012991523	0.627964438771048
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/285	40/18639	0.025	1.635	0.460437012991523	0.627964438771048
GO:0030331	nuclear estrogen receptor binding	1/285	40/18639	0.025	1.635	0.460437012991523	0.627964438771048
GO:0061791	GTPase motor activity	1/285	40/18639	0.025	1.635	0.460437012991523	0.627964438771048
GO:1990606	membrane scission GTPase motor activity	1/285	40/18639	0.025	1.635	0.460437012991523	0.627964438771048
GO:0001727	lipid kinase activity	1/285	41/18639	0.024390243902439	1.59512195121951	0.46870495488611	0.635125333352807
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/285	41/18639	0.024390243902439	1.59512195121951	0.46870495488611	0.635125333352807
GO:0005253	monoatomic anion channel activity	2/285	103/18639	0.0194174757281553	1.26990291262136	0.468884474287307	0.635125333352807
GO:0019894	kinesin binding	1/285	42/18639	0.0238095238095238	1.55714285714286	0.476846641511417	0.640091437704514
GO:0031492	nucleosomal DNA binding	1/285	42/18639	0.0238095238095238	1.55714285714286	0.476846641511417	0.640091437704514
GO:0043175	RNA polymerase core enzyme binding	1/285	42/18639	0.0238095238095238	1.55714285714286	0.476846641511417	0.640091437704514
GO:0051879	Hsp90 protein binding	1/285	42/18639	0.0238095238095238	1.55714285714286	0.476846641511417	0.640091437704514
GO:0042578	phosphoric ester hydrolase activity	6/285	363/18639	0.0165289256198347	1.08099173553719	0.481336687473218	0.644666664570872
GO:0008200	ion channel inhibitor activity	1/285	43/18639	0.0232558139534884	1.52093023255814	0.484863994158039	0.646485325544052
GO:0048156	tau protein binding	1/285	43/18639	0.0232558139534884	1.52093023255814	0.484863994158039	0.646485325544052
GO:0016248	channel inhibitor activity	1/285	44/18639	0.0227272727272727	1.48636363636364	0.492758904981064	0.653856413359078
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/285	44/18639	0.0227272727272727	1.48636363636364	0.492758904981064	0.653856413359078
GO:0005496	steroid binding	2/285	108/18639	0.0185185185185185	1.21111111111111	0.493683533576485	0.653856413359078
GO:0141110	transporter inhibitor activity	1/285	45/18639	0.0222222222222222	1.45333333333333	0.500533237440348	0.661458557681702
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/285	46/18639	0.0217391304347826	1.42173913043478	0.50818882673418	0.66713775491976
GO:0030276	clathrin binding	1/285	46/18639	0.0217391304347826	1.42173913043478	0.50818882673418	0.66713775491976
GO:0030291	protein serine/threonine kinase inhibitor activity	1/285	46/18639	0.0217391304347826	1.42173913043478	0.50818882673418	0.66713775491976
GO:0001784	phosphotyrosine residue binding	1/285	47/18639	0.0212765957446809	1.39148936170213	0.515727480226395	0.671121349814261
GO:0043495	protein-membrane adaptor activity	1/285	47/18639	0.0212765957446809	1.39148936170213	0.515727480226395	0.671121349814261
GO:0140359	ABC-type transporter activity	1/285	47/18639	0.0212765957446809	1.39148936170213	0.515727480226395	0.671121349814261
GO:0140938	histone H3 methyltransferase activity	1/285	47/18639	0.0212765957446809	1.39148936170213	0.515727480226395	0.671121349814261
GO:0140693	molecular condensate scaffold activity	1/285	48/18639	0.0208333333333333	1.3625	0.523150977867072	0.67844377526546
GO:0035401	histone H3Y41 kinase activity	2/285	115/18639	0.0173913043478261	1.13739130434783	0.52714795286763	0.67844377526546
GO:0140801	histone H2AXY142 kinase activity	2/285	115/18639	0.0173913043478261	1.13739130434783	0.52714795286763	0.67844377526546
GO:0005216	monoatomic ion channel activity	7/285	448/18639	0.015625	1.021875	0.530285113196441	0.67844377526546
GO:0001222	transcription corepressor binding	1/285	49/18639	0.0204081632653061	1.33469387755102	0.530461072606887	0.67844377526546
GO:0016763	pentosyltransferase activity	1/285	49/18639	0.0204081632653061	1.33469387755102	0.530461072606887	0.67844377526546
GO:0035254	glutamate receptor binding	1/285	49/18639	0.0204081632653061	1.33469387755102	0.530461072606887	0.67844377526546
GO:0060590	ATPase regulator activity	1/285	49/18639	0.0204081632653061	1.33469387755102	0.530461072606887	0.67844377526546
GO:0015294	solute:monoatomic cation symporter activity	2/285	116/18639	0.0172413793103448	1.12758620689655	0.531805461308844	0.678706755760323
GO:1990782	protein tyrosine kinase binding	2/285	117/18639	0.0170940170940171	1.11794871794872	0.536431692227518	0.683148052494873
GO:0032813	tumor necrosis factor receptor superfamily binding	1/285	50/18639	0.02	1.308	0.537659490805221	0.68325171965866
GO:0005048	signal sequence binding	1/285	51/18639	0.0196078431372549	1.28235294117647	0.544747932632136	0.689320101589709
GO:0030544	Hsp70 protein binding	1/285	51/18639	0.0196078431372549	1.28235294117647	0.544747932632136	0.689320101589709
GO:0008234	cysteine-type peptidase activity	3/285	187/18639	0.0160427807486631	1.04919786096257	0.547123963841505	0.690859920443934
GO:0019887	protein kinase regulator activity	4/285	255/18639	0.0156862745098039	1.02588235294118	0.549185659798903	0.691997152727581
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/285	52/18639	0.0192307692307692	1.25769230769231	0.551728072464277	0.69227353934465
GO:0030159	signaling receptor complex adaptor activity	1/285	52/18639	0.0192307692307692	1.25769230769231	0.551728072464277	0.69227353934465
GO:0015108	chloride transmembrane transporter activity	2/285	121/18639	0.0165289256198347	1.08099173553719	0.554621303742548	0.694441800484367
GO:0005246	calcium channel regulator activity	1/285	53/18639	0.0188679245283019	1.23396226415094	0.558601559274826	0.697107211542029
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/285	122/18639	0.0163934426229508	1.07213114754098	0.559089340800486	0.697107211542029
GO:0050661	NADP binding	1/285	54/18639	0.0185185185185185	1.21111111111111	0.565370017017572	0.703466660005163
GO:0016758	hexosyltransferase activity	3/285	197/18639	0.0152284263959391	0.995939086294416	0.582476962917771	0.723242228956233
GO:0140097	catalytic activity, acting on DNA	5/285	336/18639	0.0148809523809524	0.973214285714286	0.586562566986532	0.726801018552958
GO:0016798	hydrolase activity, acting on glycosyl bonds	2/285	130/18639	0.0153846153846154	1.00615384615385	0.593679523335237	0.734093352505812
GO:0070063	RNA polymerase binding	1/285	59/18639	0.0169491525423729	1.10847457627119	0.597692003927708	0.737504855638336
GO:0005261	monoatomic cation channel activity	5/285	341/18639	0.0146627565982405	0.958944281524927	0.599670040794509	0.737504855638336
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	2/285	132/18639	0.0151515151515152	0.990909090909091	0.602005109168655	0.737504855638336
GO:0001098	basal transcription machinery binding	1/285	60/18639	0.0166666666666667	1.09	0.603863036160248	0.737504855638336
GO:0001099	basal RNA polymerase II transcription machinery binding	1/285	60/18639	0.0166666666666667	1.09	0.603863036160248	0.737504855638336
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/285	60/18639	0.0166666666666667	1.09	0.603863036160248	0.737504855638336
GO:0015026	coreceptor activity	1/285	61/18639	0.0163934426229508	1.07213114754098	0.609939737527078	0.741885884828854
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	1/285	61/18639	0.0163934426229508	1.07213114754098	0.609939737527078	0.741885884828854
GO:0004536	DNA nuclease activity	1/285	64/18639	0.015625	1.021875	0.627618117186515	0.761833804161227
GO:0038024	cargo receptor activity	1/285	65/18639	0.0153846153846154	1.00615384615385	0.633331648093747	0.763479778131693
GO:0120013	lipid transfer activity	1/285	65/18639	0.0153846153846154	1.00615384615385	0.633331648093747	0.763479778131693
GO:0004713	protein tyrosine kinase activity	2/285	140/18639	0.0142857142857143	0.934285714285714	0.634019828405507	0.763479778131693
GO:0035091	phosphatidylinositol binding	4/285	284/18639	0.0140845070422535	0.92112676056338	0.634098137877832	0.763479778131693
GO:0042054	histone methyltransferase activity	1/285	67/18639	0.0149253731343284	0.976119402985075	0.644497958112935	0.774437062571188
GO:0003777	microtubule motor activity	1/285	68/18639	0.0147058823529412	0.961764705882353	0.649953379281243	0.777855851509279
GO:1990841	promoter-specific chromatin binding	1/285	68/18639	0.0147058823529412	0.961764705882353	0.649953379281243	0.777855851509279
GO:0002039	p53 binding	1/285	69/18639	0.0144927536231884	0.947826086956522	0.655325372545194	0.781147844073872
GO:0016279	protein-lysine N-methyltransferase activity	1/285	69/18639	0.0144927536231884	0.947826086956522	0.655325372545194	0.781147844073872
GO:0015293	symporter activity	2/285	146/18639	0.0136986301369863	0.895890410958904	0.656688374294415	0.78120369990484
GO:0015085	calcium ion transmembrane transporter activity	2/285	147/18639	0.0136054421768707	0.889795918367347	0.660355772329238	0.78120369990484
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/285	70/18639	0.0142857142857143	0.934285714285714	0.660615209315503	0.78120369990484
GO:0016278	lysine N-methyltransferase activity	1/285	70/18639	0.0142857142857143	0.934285714285714	0.660615209315503	0.78120369990484
GO:0008509	monoatomic anion transmembrane transporter activity	2/285	149/18639	0.0134228187919463	0.877852348993289	0.667596494816427	0.787465494397985
GO:0046982	protein heterodimerization activity	5/285	369/18639	0.013550135501355	0.886178861788618	0.668552919740571	0.787465494397985
GO:0004521	RNA endonuclease activity	1/285	73/18639	0.0136986301369863	0.895890410958904	0.6760042068944	0.793107297852485
GO:0043539	protein serine/threonine kinase activator activity	1/285	73/18639	0.0136986301369863	0.895890410958904	0.6760042068944	0.793107297852485
GO:0031491	nucleosome binding	1/285	74/18639	0.0135135135135135	0.883783783783784	0.680977749985809	0.797372768156271
GO:0005506	iron ion binding	2/285	154/18639	0.012987012987013	0.849350649350649	0.685154444079395	0.800249240611327
GO:0005085	guanyl-nucleotide exchange factor activity	3/285	230/18639	0.0130434782608696	0.85304347826087	0.686119734819443	0.800249240611327
GO:0015631	tubulin binding	5/285	385/18639	0.012987012987013	0.849350649350649	0.704260634832929	0.818747332798944
GO:0015370	solute:sodium symporter activity	1/285	79/18639	0.0126582278481013	0.827848101265823	0.704727150546742	0.818747332798944
GO:0000049	tRNA binding	1/285	80/18639	0.0125	0.8175	0.709261243331989	0.820814953448282
GO:0048306	calcium-dependent protein binding	1/285	80/18639	0.0125	0.8175	0.709261243331989	0.820814953448282
GO:0015101	organic cation transmembrane transporter activity	1/285	81/18639	0.0123456790123457	0.807407407407407	0.713725952941902	0.822786591786023
GO:0030971	receptor tyrosine kinase binding	1/285	81/18639	0.0123456790123457	0.807407407407407	0.713725952941902	0.822786591786023
GO:0015103	inorganic anion transmembrane transporter activity	2/285	165/18639	0.0121212121212121	0.792727272727273	0.721111899967419	0.82963594897503
GO:0030165	PDZ domain binding	1/285	83/18639	0.0120481927710843	0.787951807228916	0.722451438788659	0.82963594897503
GO:0004527	exonuclease activity	1/285	84/18639	0.0119047619047619	0.778571428571429	0.726714283148717	0.831327663640375
GO:0004860	protein kinase inhibitor activity	1/285	84/18639	0.0119047619047619	0.778571428571429	0.726714283148717	0.831327663640375
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	1/285	89/18639	0.0112359550561798	0.734831460674157	0.747069486525427	0.851344959788058
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	1/285	89/18639	0.0112359550561798	0.734831460674157	0.747069486525427	0.851344959788058
GO:0019210	kinase inhibitor activity	1/285	90/18639	0.0111111111111111	0.726666666666667	0.7509554809373	0.852513269787869
GO:0140793	histone H2AXY142 phosphatase activity	1/285	90/18639	0.0111111111111111	0.726666666666667	0.7509554809373	0.852513269787869
GO:0004252	serine-type endopeptidase activity	2/285	176/18639	0.0113636363636364	0.743181818181818	0.753554854764274	0.853605424464026
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	1/285	91/18639	0.010989010989011	0.718681318681319	0.75478197767205	0.853605424464026
GO:0052689	carboxylic ester hydrolase activity	1/285	92/18639	0.0108695652173913	0.710869565217391	0.758549884527962	0.856241915111109
GO:0016410	N-acyltransferase activity	1/285	94/18639	0.0106382978723404	0.695744680851064	0.765913490991938	0.862636970610719
GO:0003730	mRNA 3'-UTR binding	3/285	262/18639	0.0114503816793893	0.748854961832061	0.767110057757854	0.862636970610719
GO:0008276	protein methyltransferase activity	1/285	95/18639	0.0105263157894737	0.688421052631579	0.769510938016327	0.863707192199117
GO:1901981	phosphatidylinositol phosphate binding	2/285	185/18639	0.0108108108108108	0.707027027027027	0.777636500118215	0.868907911899241
GO:0004725	protein tyrosine phosphatase activity	1/285	98/18639	0.0102040816326531	0.66734693877551	0.779976061855862	0.868907911899241
GO:0005249	voltage-gated potassium channel activity	1/285	98/18639	0.0102040816326531	0.66734693877551	0.779976061855862	0.868907911899241
GO:0008170	N-methyltransferase activity	1/285	98/18639	0.0102040816326531	0.66734693877551	0.779976061855862	0.868907911899241
GO:0043130	ubiquitin binding	1/285	100/18639	0.01	0.654	0.786688379808566	0.874750511876689
GO:0045182	translation regulator activity	4/285	356/18639	0.0112359550561798	0.734831460674157	0.796715803891147	0.884250687372669
GO:0008236	serine-type peptidase activity	2/285	194/18639	0.0103092783505155	0.674226804123711	0.799639521582389	0.885846012756698
GO:0008013	beta-catenin binding	1/285	106/18639	0.00943396226415094	0.616981132075472	0.805625415729832	0.890821424443376
GO:0019888	protein phosphatase regulator activity	1/285	107/18639	0.00934579439252336	0.611214953271028	0.808614503115414	0.891010091796633
GO:0017171	serine hydrolase activity	2/285	198/18639	0.0101010101010101	0.660606060606061	0.808786006144259	0.891010091796633
GO:0004518	nuclease activity	2/285	209/18639	0.00956937799043062	0.625837320574163	0.832052073595777	0.914950250669895
GO:0019208	phosphatase regulator activity	1/285	117/18639	0.00854700854700855	0.558974358974359	0.83609796256219	0.917706050989071
GO:0032182	ubiquitin-like protein binding	1/285	120/18639	0.00833333333333333	0.545	0.843548472543262	0.923668151956383
GO:0004540	RNA nuclease activity	1/285	121/18639	0.00826446280991736	0.540495867768595	0.845956198949935	0.923668151956383
GO:0140098	catalytic activity, acting on RNA	4/285	387/18639	0.0103359173126615	0.675968992248062	0.846179213033868	0.923668151956383
GO:0008528	G protein-coupled peptide receptor activity	1/285	122/18639	0.00819672131147541	0.536065573770492	0.848326999430509	0.924319728812766
GO:0005267	potassium channel activity	1/285	124/18639	0.00806451612903226	0.52741935483871	0.852960071411413	0.927671902483945
GO:0004519	endonuclease activity	1/285	127/18639	0.0078740157480315	0.51496062992126	0.859646567030004	0.933241081875925
GO:0001653	peptide receptor activity	1/285	128/18639	0.0078125	0.5109375	0.86180736696499	0.933885801292971
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1/285	130/18639	0.00769230769230769	0.503076923076923	0.866030019227222	0.936758423701315
GO:0005262	calcium channel activity	1/285	131/18639	0.00763358778625954	0.499236641221374	0.868092877540488	0.937121043119607
GO:0000287	magnesium ion binding	2/285	230/18639	0.00869565217391304	0.568695652173913	0.869509961149568	0.937121043119607
GO:0030695	GTPase regulator activity	5/285	489/18639	0.0102249488752556	0.668711656441718	0.871591642427864	0.937176605179847
GO:0060589	nucleoside-triphosphatase regulator activity	5/285	490/18639	0.0102040816326531	0.66734693877551	0.872706402474522	0.937176605179847
GO:0016779	nucleotidyltransferase activity	1/285	136/18639	0.00735294117647059	0.480882352941176	0.877941930262554	0.937730090387961
GO:0099094	ligand-gated monoatomic cation channel activity	1/285	136/18639	0.00735294117647059	0.480882352941176	0.877941930262554	0.937730090387961
GO:0140789	histone phosphatase activity	1/285	136/18639	0.00735294117647059	0.480882352941176	0.877941930262554	0.937730090387961
GO:0022843	voltage-gated monoatomic cation channel activity	1/285	143/18639	0.00699300699300699	0.457342657342657	0.890511469411325	0.949454089032468
GO:0004674	protein serine/threonine kinase activity	4/285	433/18639	0.0092378752886836	0.604157043879908	0.90068739939482	0.958588732213059
GO:0015079	potassium ion transmembrane transporter activity	1/285	160/18639	0.00625	0.40875	0.915924348451093	0.97147828661834
GO:0046873	metal ion transmembrane transporter activity	4/285	450/18639	0.00888888888888889	0.581333333333333	0.916058384361589	0.97147828661834
GO:0015081	sodium ion transmembrane transporter activity	1/285	164/18639	0.00609756097560976	0.398780487804878	0.920992752463361	0.972558564413975
GO:0005096	GTPase activator activity	2/285	271/18639	0.00738007380073801	0.482656826568266	0.921473169141815	0.972558564413975
GO:0016791	phosphatase activity	2/285	273/18639	0.00732600732600733	0.479120879120879	0.92342919579497	0.972558564413975
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	1/285	167/18639	0.00598802395209581	0.391616766467066	0.924593187537164	0.972558564413975
GO:0005525	GTP binding	3/285	378/18639	0.00793650793650794	0.519047619047619	0.930906483332626	0.972558564413975
GO:0005244	voltage-gated monoatomic ion channel activity	1/285	173/18639	0.00578034682080925	0.378034682080925	0.931310882483291	0.972558564413975
GO:0004721	phosphoprotein phosphatase activity	1/285	175/18639	0.00571428571428571	0.373714285714286	0.933414841281956	0.972558564413975
GO:0022832	voltage-gated channel activity	1/285	175/18639	0.00571428571428571	0.373714285714286	0.933414841281956	0.972558564413975
GO:0015291	secondary active transmembrane transporter activity	2/285	287/18639	0.00696864111498258	0.455749128919861	0.935890755228187	0.972558564413975
GO:0005319	lipid transporter activity	1/285	178/18639	0.00561797752808989	0.367415730337079	0.936450969780681	0.972558564413975
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	4/285	484/18639	0.00826446280991736	0.540495867768595	0.940593623918777	0.972558564413975
GO:0015276	ligand-gated monoatomic ion channel activity	1/285	186/18639	0.00537634408602151	0.351612903225806	0.943889604474142	0.972558564413975
GO:0001216	DNA-binding transcription activator activity	4/285	491/18639	0.00814663951120163	0.532790224032586	0.944756219614461	0.972558564413975
GO:0022834	ligand-gated channel activity	1/285	188/18639	0.00531914893617021	0.347872340425532	0.945609476380142	0.972558564413975
GO:0046943	carboxylic acid transmembrane transporter activity	1/285	188/18639	0.00531914893617021	0.347872340425532	0.945609476380142	0.972558564413975
GO:0019001	guanyl nucleotide binding	3/285	400/18639	0.0075	0.4905	0.94611850005195	0.972558564413975
GO:0032561	guanyl ribonucleotide binding	3/285	400/18639	0.0075	0.4905	0.94611850005195	0.972558564413975
GO:0005342	organic acid transmembrane transporter activity	1/285	189/18639	0.00529100529100529	0.346031746031746	0.946449609664607	0.972558564413975
GO:0016829	lyase activity	1/285	200/18639	0.005	0.327	0.954879732116831	0.979532393014856
GO:0008168	methyltransferase activity	1/285	204/18639	0.00490196078431373	0.320588235294118	0.957605519505175	0.980640703823168
GO:0030371	translation repressor activity	2/285	329/18639	0.0060790273556231	0.397568389057751	0.962750302125638	0.982416295732054
GO:0003924	GTPase activity	2/285	331/18639	0.00604229607250755	0.395166163141994	0.963713469127454	0.982416295732054
GO:0016741	transferase activity, transferring one-carbon groups	1/285	215/18639	0.00465116279069767	0.304186046511628	0.964284451347737	0.982416295732054
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	1/285	229/18639	0.00436681222707424	0.285589519650655	0.971289852223048	0.985177135620194
GO:0061630	ubiquitin protein ligase activity	2/285	353/18639	0.0056657223796034	0.370538243626062	0.972848892783254	0.985177135620194
GO:0141003	histone H2AX kinase activity	2/285	354/18639	0.00564971751412429	0.369491525423729	0.973206574230066	0.985177135620194
GO:0140996	histone H3 kinase activity	2/285	357/18639	0.00560224089635854	0.366386554621849	0.974252606079601	0.985177135620194
GO:0035173	histone kinase activity	2/285	360/18639	0.00555555555555556	0.363333333333333	0.975259244993146	0.985177135620194
GO:0061659	ubiquitin-like protein ligase activity	2/285	372/18639	0.00537634408602151	0.351612903225806	0.978919345125424	0.987201234678093
GO:0008514	organic anion transmembrane transporter activity	1/285	269/18639	0.00371747211895911	0.243122676579926	0.984628553046199	0.99128144867489
GO:0004842	ubiquitin-protein transferase activity	2/285	449/18639	0.0044543429844098	0.291314031180401	0.992598365443905	0.996147524148251
GO:0022836	gated channel activity	1/285	318/18639	0.00314465408805031	0.205660377358491	0.992862693967252	0.996147524148251
GO:0019787	ubiquitin-like protein transferase activity	2/285	479/18639	0.00417536534446764	0.273068893528184	0.995115814091481	0.996147524148251
GO:0016755	aminoacyltransferase activity	2/285	496/18639	0.00403225806451613	0.263709677419355	0.996147524148251	0.996147524148251