category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Genetic Information Processing	Translation	hsa03010	Ribosome	11/74	222/9376	6.27806184562941	RPL13A/RPS20/RPS26/RPL10/RPS28/RPS11/RPL28/RPS8/RPL37A/RPL18A/RPL23	7.09837335661794
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	11/74	238/9376	5.85600726777197	RPL13A/RPS20/RPS26/RPL10/RPS28/RPS11/RPL28/RPS8/RPL37A/RPL18A/RPL23	6.76792535623304
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	8/74	138/9376	7.34508421464943	MT-CYB/MT-CO3/MT-CO2/MT-ND1/MT-ND3/MT-ATP6/COX7A1/MT-ND2	6.69732362670538
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	8/74	205/9376	4.94449571522742	MT-CYB/MT-CO3/MT-CO2/MT-ND1/MT-ND3/MT-ATP6/COX7A1/MT-ND2	5.09299679550567
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	8/74	227/9376	4.46529348731992	MT-CYB/MT-CO3/MT-CO2/MT-ND1/MT-ND3/MT-ATP6/COX7A1/MT-ND2	4.71389025745567
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	8/74	235/9376	4.31328349626222	MT-CYB/MT-CO3/MT-CO2/MT-ND1/MT-ND3/MT-ATP6/COX7A1/MT-ND2	4.58784782601972
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	5/74	87/9376	7.28176452314383	MT-CYB/MT-CO3/MT-CO2/TPM1/COX7A1	5.25013085366123
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	5/74	88/9376	7.1990171990172	SERPINE1/SERPINE2/SERPING1/CLU/F2R	5.21094398179573
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	9/74	308/9376	3.7023517023517	MT-CYB/MT-CO3/MT-CO2/TGM2/MT-ND1/MT-ND3/MT-ATP6/COX7A1/MT-ND2	4.3010530909297
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	8/74	268/9376	3.78217022993142	MT-CYB/MT-CO3/MT-CO2/MT-ND1/MT-ND3/MT-ATP6/COX7A1/MT-ND2	4.12147733353486
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	8/74	275/9376	3.68589680589681	MT-CYB/MT-CO3/MT-CO2/MT-ND1/MT-ND3/MT-ATP6/COX7A1/MT-ND2	4.03203638903991
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	9/74	388/9376	2.93898021733073	MT-CYB/MT-CO3/MT-CO2/DKK1/MT-ND1/MT-ND3/MT-ATP6/COX7A1/MT-ND2	3.47913306669603
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	3/74	42/9376	9.05019305019305	FTH1/FTL/SAT1	4.66348272812902
NA	NA	hsa04382	Cornified envelope formation	6/74	217/9376	3.5033005355586	S100A6/KRT18/KRT8/KRT19/KRT7/S100A4	3.32760800339202
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	8/74	368/9376	2.75440658049354	MT-CYB/MT-CO3/MT-CO2/MT-ND1/MT-ND3/MT-ATP6/COX7A1/MT-ND2	3.06233923558442
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	6/74	233/9376	3.2627305417005	FN1/DCN/FBLN1/MYL9/TPM1/LMNA	3.11946250553955
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	9/74	480/9376	2.37567567567568	MT-CYB/MT-CO3/MT-CO2/DKK1/MT-ND1/MT-ND3/MT-ATP6/COX7A1/MT-ND2	2.7596412012945
NA	NA	hsa04518	Integrin signaling	4/74	154/9376	3.29097929097929	FN1/FLT1/SPP1/FERMT2	2.55671485870012
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	4/74	157/9376	3.22809433637459	MT-CYB/MT-CO3/MT-CO2/COX7A1	2.51104689757812
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	3/74	103/9376	3.69036998163212	FN1/HSPB1/IL1R1	2.44869007826251
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/74	46/9376	5.50881316098707	FTH1/FTL	2.73409539591393
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	3/74	110/9376	3.45552825552826	FLT1/TIMP1/SERPINE1	2.31051323730047
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	2/74	50/9376	5.06810810810811	SAT1/AOC1	2.57242731636224
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	6/74	362/9376	2.10004479617739	FN1/FLT1/PRL/SPP1/PRLR/F2R	1.90379073871072
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	4/74	203/9376	2.4966049793636	FN1/FLT1/MYL9/SPP1	1.92270580939889
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	4/74	204/9376	2.48436671966084	TIMP3/FN1/LUM/DCN	1.91177861722276
Organismal Systems	Digestive system	hsa04978	Mineral absorption	2/74	61/9376	4.15418697385911	FTH1/FTL	2.20431802640787
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	5/74	298/9376	2.12588427353528	IL1RL1/PRL/IL1R1/PRLR/CXCL14	1.76165202030795
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	3/74	134/9376	2.83662767244857	CALD1/MYL9/RAMP1	1.90987028222987
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/74	71/9376	3.56909021697754	PRL/PRLR	1.93804417275822
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	3/74	149/9376	2.55106112824234	MT-ND1/MT-ND3/MT-ND2	1.70217856912774
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/74	75/9376	3.37873873873874	IGFBP3/SERPINE1	1.8447005841043
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/74	157/9376	2.42107075228094	IGFBP3/SERPINE1/HLA-E	1.60153690330738
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	2/74	82/9376	3.09030982201714	CD74/HLA-E	1.69562411267592
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/74	89/9376	2.84725174612815	FN1/SPP1	1.56169671503015
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/74	22/9376	5.75921375921376	AOC1	1.99324736936928
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/74	99/9376	2.55965055965056	KRT18/KRT19	1.39140786812248
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	2/74	99/9376	2.55965055965056	TPM1/LMNA	1.39140786812248
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/74	100/9376	2.53405405405405	IL1R1/CD3G	1.37554126451969
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/74	101/9376	2.50896440995451	FN1/SERPINE1	1.35986581050544
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/74	103/9376	2.46024665442141	SERPINE1/CD3G	1.32907054379507
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/74	105/9376	2.41338481338481	TPM1/LMNA	1.29898791311233
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	3/74	201/9376	1.89108511496571	IGFBP3/FLT1/NUPR1	1.13900993396554
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/74	109/9376	2.32482023307711	IL1R1/CD3G	1.24083475734809
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/74	110/9376	2.3036855036855	DCN/EMP3	1.22669434031582
Human Diseases	Immune disease	hsa05310	Asthma	1/74	32/9376	3.95945945945946	PRG2	1.49566489322856
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/74	116/9376	2.18452935694315	THY1/MYL9	1.14493982085668
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/74	34/9376	3.72655007949126	RORB	1.42051667604899
NA	NA	hsa04081	Hormone signaling	3/74	219/9376	1.73565346168086	PRL/PRLR/RAMP1	0.982498879441386
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	3/74	224/9376	1.6969111969112	IL1R1/HLA-E/CD3G	0.941579026429334
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/74	226/9376	1.6818942836642	MYL9/F2R/FXYD1	0.925494948778626
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/74	39/9376	3.24878724878725	HLA-E	1.25513466587921
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	3/74	232/9376	1.63839701770736	FN1/MYL9/F2R	0.87817296653191
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/74	42/9376	3.01673101673102	AOC1	1.16829375459283
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/74	44/9376	2.87960687960688	HLA-E	1.11460074650191
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/74	139/9376	1.82306047054249	KRT18/KRT19	0.871940806478918
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/74	45/9376	2.81561561561562	HLA-E	1.08887844804304
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/74	140/9376	1.81003861003861	SERPINE1/SPP1	0.861273541827219
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	3/74	253/9376	1.50240358936011	MYL9/IL1R1/UBE2D1	0.72253266705096
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	4/74	370/9376	1.36975894813733	PRL/NPW/PRLR/F2R	0.647242331874551
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/74	54/9376	2.34634634634635	HLA-E	0.884937210863973
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/74	60/9376	2.11171171171171	HSPB1	0.770488918070057
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/74	168/9376	1.50836550836551	FTH1/FTL	0.593009147776336
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/74	168/9376	1.50836550836551	PRL/PRLR	0.593009147776336
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/74	62/9376	2.04359197907585	CRYAB	0.735312232618226
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/74	63/9376	2.01115401115401	PTGDS	0.71821771473267
NA	NA	hsa04519	Cadherin signaling	4/74	404/9376	1.25448220497725	KRT18/KRT8/KRT19/KRT7	0.466355174256135
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	2/74	174/9376	1.45635290462877	CRYAB/UBE2D1	0.541935572927195
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/74	65/9376	1.94927234927235	SPP1	0.684956003070299
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/74	66/9376	1.91973791973792	HSD11B1	0.668766561402036
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	2/74	178/9376	1.42362587306408	DKK1/NOTUM	0.508931234946363
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	2/74	180/9376	1.40780780780781	CD74/HLA-E	0.492726179920446
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	3/74	300/9376	1.26702702702703	FLT1/HSPB1/IL1R1	0.419258556519467
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/74	70/9376	1.81003861003861	HSD11B1	0.606717534034009
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/74	70/9376	1.81003861003861	HLA-E	0.606717534034009
Cellular Processes	Cell motility	hsa04814	Motor proteins	2/74	194/9376	1.30621342992477	MYL9/TPM1	0.384387968237071
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/74	78/9376	1.62439362439362	FN1	0.493883276640918
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/74	78/9376	1.62439362439362	SERPING1	0.493883276640918
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/74	79/9376	1.60383167978105	HSD11B1	0.480696937216884
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	2/74	200/9376	1.26702702702703	IL1R1/F2R	0.34045274988278
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/74	83/9376	1.52653858677955	UBE2D1	0.429738844309438
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	2/74	205/9376	1.23612392880686	HLA-E/CD3G	0.304875071384427
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/74	333/9376	1.14146579011444	FN1/SPP1/HLA-E	0.234439405465277
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/74	86/9376	1.4732872407291	LMNA	0.393259747159469
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	2/74	212/9376	1.19530851606323	FLT1/F2R	0.25654284165119
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/74	214/9376	1.18413740843647	HLA-E/CD3G	0.243034036468023
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/74	90/9376	1.40780780780781	CD3G	0.34671751553224
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/74	93/9376	1.36239465271723	MYL9	0.313250959829087
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/74	93/9376	1.36239465271723	CD3G	0.313250959829087
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/74	93/9376	1.36239465271723	CST3	0.313250959829087
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/74	93/9376	1.36239465271723	FN1	0.313250959829087
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/74	95/9376	1.33371266002845	FLT1	0.291575097516015
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	2/74	227/9376	1.11632337182998	IL1R1/HLA-E	0.158236412353004
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/74	99/9376	1.27982527982528	IL1R1	0.24963995533442
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/74	100/9376	1.26702702702703	CXCL14	0.23943530115318
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/74	105/9376	1.20669240669241	IL1R1	0.189963083997305
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/74	109/9376	1.16241011653856	SPP1	0.152114311447314
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/74	254/9376	0.997659076399234	FLT1/F2R	-0.00337343537648737
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/74	122/9376	1.03854674346478	CD3G	0.0382222449852644
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/74	122/9376	1.03854674346478	IGFBP3	0.0382222449852644
Organismal Systems	Immune system	hsa04611	Platelet activation	1/74	126/9376	1.00557700557701	F2R	0.00562119712484315
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/74	133/9376	0.952651900020321	HLA-E	-0.0490495729371621
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/74	136/9376	0.931637519872814	CD3G	-0.0716249957468995
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/74	137/9376	0.924837246005129	LMNA	-0.0790430727717333
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/74	138/9376	0.918135526831179	FN1	-0.0864090769789138
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/74	142/9376	0.892272554244385	UBE2D1	-0.115368947414743
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/74	142/9376	0.892272554244385	IL1R1	-0.115368947414743
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/74	142/9376	0.892272554244385	IL1R1	-0.115368947414743
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/74	149/9376	0.850353709414112	F2R	-0.164226092799717
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/74	154/9376	0.822744822744823	TPM1	-0.197815382816541
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	1/74	154/9376	0.822744822744823	MYL9	-0.197815382816541
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/74	155/9376	0.81743679163034	HLA-E	-0.204410607057053
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/74	157/9376	0.807023584093648	SERPINE1	-0.217483085234109
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/74	158/9376	0.801915839890523	CDKN1C	-0.223961449914078
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	1/74	160/9376	0.791891891891892	HLA-E	-0.236805120965755
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	2/74	323/9376	0.784536858840264	TIMP3/TPM1	-0.351472474046155
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/74	166/9376	0.763269293389775	MYL9	-0.274468275619713
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/74	170/9376	0.745310015898251	MYL9	-0.298891918179652
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/74	181/9376	0.700014932059131	CD74	-0.363476543068274
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/74	184/9376	0.688601645123384	MYL9	-0.380481502542128
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/74	193/9376	0.65649068757877	CXCL14	-0.430069068181351
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/74	196/9376	0.646442360728075	HLA-E	-0.446149336012918
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	1/74	205/9376	0.618061964403428	HLA-E	-0.493145215969114
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/74	238/9376	0.532364297070179	FLT1	-0.651754282235809
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/74	248/9376	0.510897994768962	MYL9	-0.696226899208493
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/74	250/9376	0.506810810810811	HLA-E	-0.7049472988662
NA	NA	hsa04517	IgSF CAM signaling	1/74	299/9376	0.423754858537467	MYL9	-0.903202297472581