ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0031994 insulin-like growth factor I binding 6/49 13/18639 0.461538461538462 175.563579277865 4.0669599641711e-13 6.38512714374862e-11 GO:0005520 insulin-like growth factor binding 6/49 19/18639 0.315789473684211 120.122448979592 6.3544020285773e-12 4.98820559243318e-10 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 7/49 68/18639 0.102941176470588 39.1575630252101 4.76596165233827e-10 2.49418659805703e-08 GO:0003735 structural constituent of ribosome 9/49 175/18639 0.0514285714285714 19.5627988338192 6.86237120965046e-10 2.69348069978781e-08 GO:0019838 growth factor binding 8/49 136/18639 0.0588235294117647 22.37575030012 2.28889610859917e-09 7.1871337810014e-08 GO:0009055 electron transfer activity 7/49 116/18639 0.0603448275862069 22.9544334975369 2.0847676294712e-08 5.06000002253774e-07 GO:0022853 active monoatomic ion transmembrane transporter activity 7/49 118/18639 0.0593220338983051 22.5653753026634 2.34796722800141e-08 5.06000002253774e-07 GO:0015078 proton transmembrane transporter activity 8/49 185/18639 0.0432432432432432 16.4492002206288 2.57834396052878e-08 5.06000002253774e-07 GO:0015399 primary active transmembrane transporter activity 7/49 166/18639 0.0421686746987952 16.0404475043029 2.45532259478571e-07 4.28317385979285e-06 GO:0001968 fibronectin binding 4/49 30/18639 0.133333333333333 50.7183673469388 1.09836642262456e-06 1.72443528352055e-05 GO:0008137 NADH dehydrogenase (ubiquinone) activity 4/49 41/18639 0.0975609756097561 37.1110004977601 3.97347913111716e-06 5.67123839623086e-05 GO:0003954 NADH dehydrogenase activity 4/49 44/18639 0.0909090909090909 34.5807050092764 5.29562576495697e-06 6.92844370915203e-05 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 4/49 58/18639 0.0689655172413793 26.2336382828994 1.61094092449301e-05 0.000194552096265695 GO:0016651 oxidoreductase activity, acting on NAD(P)H 4/49 88/18639 0.0454545454545455 17.2903525046382 8.35634273169326e-05 0.00093710414919703 GO:0004857 enzyme inhibitor activity 7/49 416/18639 0.0168269230769231 6.40075549450549 0.00010032787860925 0.00105009846277681 GO:0022804 active transmembrane transporter activity 7/49 457/18639 0.0153172866520788 5.8265082838387 0.000179397709194206 0.00176034002146814 GO:0061134 peptidase regulator activity 5/49 226/18639 0.0221238938053097 8.41565829871772 0.000309641443401935 0.00285962980082964 GO:1990948 ubiquitin ligase inhibitor activity 2/49 11/18639 0.181818181818182 69.1614100185529 0.00036678001072714 0.00319913676023116 GO:0004129 cytochrome-c oxidase activity 2/49 15/18639 0.133333333333333 50.7183673469388 0.000695527712794662 0.00545989254543809 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/49 15/18639 0.133333333333333 50.7183673469388 0.000695527712794662 0.00545989254543809 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/49 16/18639 0.125 47.5484693877551 0.000793555382929131 0.00593277119618445 GO:0048038 quinone binding 2/49 17/18639 0.117647058823529 44.7515006002401 0.000897854339440565 0.00640741505873494 GO:0005201 extracellular matrix structural constituent 4/49 168/18639 0.0238095238095238 9.05685131195335 0.000983682354458485 0.00671470128912966 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/49 22/18639 0.0909090909090909 34.5807050092764 0.0015122923406234 0.00989291239491138 GO:0023026 MHC class II protein complex binding 2/49 27/18639 0.0740740740740741 28.1768707482993 0.00227871932520935 0.0143103573623147 GO:0005539 glycosaminoglycan binding 4/49 242/18639 0.0165289256198347 6.28740091077753 0.00371572890740108 0.0224372860946912 GO:0055106 ubiquitin-protein transferase regulator activity 2/49 36/18639 0.0555555555555556 21.1326530612245 0.00402884115175095 0.023426965215737 GO:0023023 MHC protein complex binding 2/49 37/18639 0.0540540540540541 20.561500275786 0.00425194202191023 0.0238412463371395 GO:0004866 endopeptidase inhibitor activity 3/49 161/18639 0.0186335403726708 7.08797059196349 0.00871417340135337 0.0471767318624993 GO:0016504 peptidase activator activity 2/49 57/18639 0.0350877192982456 13.3469387755102 0.00985469098194556 0.0503484413360281 GO:0030414 peptidase inhibitor activity 3/49 169/18639 0.0177514792899408 6.75244535684096 0.00994141198354694 0.0503484413360281 GO:0008201 heparin binding 3/49 172/18639 0.0174418604651163 6.63467014712862 0.0104262943102026 0.0511540064594313 GO:0045296 cadherin binding 4/49 334/18639 0.0119760479041916 4.55554197726995 0.0113878748676857 0.0541786774008079 GO:0005507 copper ion binding 2/49 63/18639 0.0317460317460317 12.0758017492711 0.0119390972501005 0.0551305373019345 GO:0061135 endopeptidase regulator activity 3/49 184/18639 0.016304347826087 6.20197426796806 0.0125022200745982 0.0552692800435277 GO:0019843 rRNA binding 2/49 65/18639 0.0307692307692308 11.7042386185243 0.0126732107106178 0.0552692800435277 GO:0050840 extracellular matrix binding 2/49 67/18639 0.0298507462686567 11.354858361255 0.0134266186881335 0.056972409028026 GO:0097110 scaffold protein binding 2/49 70/18639 0.0285714285714286 10.868221574344 0.0145924397101911 0.0602898166973686 GO:0005518 collagen binding 2/49 72/18639 0.0277777777777778 10.5663265306122 0.0153931503357613 0.0619672975055007 GO:0044183 protein folding chaperone 2/49 75/18639 0.0266666666666667 10.1436734693878 0.0166289358151324 0.0652685730743946 GO:0017022 myosin binding 2/49 76/18639 0.0263157894736842 10.0102040816327 0.0170500186834649 0.0652890959342438 GO:0001540 amyloid-beta binding 2/49 83/18639 0.0240963855421687 9.16597000245882 0.0201231195794912 0.0752221374757171 GO:0004867 serine-type endopeptidase inhibitor activity 2/49 95/18639 0.0210526315789474 8.00816326530612 0.0258832237210049 0.0945038633534365 GO:0042277 peptide binding 3/49 249/18639 0.0120481927710843 4.58298500122941 0.0276488531650522 0.0986561351571181 GO:0050998 nitric-oxide synthase binding 1/49 11/18639 0.0909090909090909 34.5807050092764 0.0285482908415352 0.0996018147138006 GO:0097371 MDM2/MDM4 family protein binding 1/49 12/18639 0.0833333333333333 31.6989795918367 0.0311036448112988 0.106158092073346 GO:0019888 protein phosphatase regulator activity 2/49 107/18639 0.0186915887850467 7.11005149723441 0.0322284237441303 0.107656649528265 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/49 13/18639 0.0769230769230769 29.2605965463108 0.0336524138779358 0.110071437059082 GO:1901681 sulfur compound binding 3/49 275/18639 0.0109090909090909 4.14968460111317 0.0355747407444547 0.111422637278942 GO:0008191 metalloendopeptidase inhibitor activity 1/49 14/18639 0.0714285714285714 27.1705539358601 0.0361946146574907 0.111422637278942 GO:0032036 myosin heavy chain binding 1/49 14/18639 0.0714285714285714 27.1705539358601 0.0361946146574907 0.111422637278942 GO:0019208 phosphatase regulator activity 2/49 117/18639 0.0170940170940171 6.50235478806907 0.0379338238633505 0.114530968202808 GO:0005523 tropomyosin binding 1/49 15/18639 0.0666666666666667 25.3591836734694 0.0387302637249688 0.114729271789059 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/49 16/18639 0.0625 23.7742346938776 0.041259377614438 0.117776768826668 GO:0019841 retinol binding 1/49 16/18639 0.0625 23.7742346938776 0.041259377614438 0.117776768826668 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/49 18/18639 0.0555555555555556 21.1326530612245 0.0462980657915162 0.125324074642552 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/49 18/18639 0.0555555555555556 21.1326530612245 0.0462980657915162 0.125324074642552 GO:0098641 cadherin binding involved in cell-cell adhesion 1/49 18/18639 0.0555555555555556 21.1326530612245 0.0462980657915162 0.125324074642552 GO:0016918 retinal binding 1/49 19/18639 0.0526315789473684 20.0204081632653 0.0488076729434529 0.129878044951222 GO:0002020 protease binding 2/49 136/18639 0.0147058823529412 5.59393757503001 0.0497365479068112 0.130143967022823 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/49 20/18639 0.05 19.019387755102 0.0513108106462337 0.132062250351782 GO:0072542 protein phosphatase activator activity 1/49 21/18639 0.0476190476190476 18.1137026239067 0.0538074952307082 0.136254463729374 GO:0005212 structural constituent of eye lens 1/49 23/18639 0.0434782608695652 16.5385980479148 0.0587815701664957 0.144198539314685 GO:0017134 fibroblast growth factor binding 1/49 23/18639 0.0434782608695652 16.5385980479148 0.0587815701664957 0.144198539314685 GO:0019211 phosphatase activator activity 1/49 25/18639 0.04 15.2155102040816 0.0637300275923944 0.153932528184707 GO:0005178 integrin binding 2/49 161/18639 0.0124223602484472 4.72531372797566 0.0669815075647842 0.158507654166519 GO:0015252 proton channel activity 1/49 27/18639 0.037037037037037 14.0884353741497 0.0686529967090654 0.158507654166519 GO:0035255 ionotropic glutamate receptor binding 1/49 27/18639 0.037037037037037 14.0884353741497 0.0686529967090654 0.158507654166519 GO:0043394 proteoglycan binding 1/49 37/18639 0.027027027027027 10.280750137893 0.0928899952017735 0.202685131377222 GO:0005501 retinoid binding 1/49 38/18639 0.0263157894736842 10.0102040816327 0.0952794366723204 0.202685131377222 GO:0019840 isoprenoid binding 1/49 38/18639 0.0263157894736842 10.0102040816327 0.0952794366723204 0.202685131377222 GO:0042287 MHC protein binding 1/49 41/18639 0.024390243902439 9.27775012444002 0.102410827553731 0.202685131377222 GO:0008307 structural constituent of muscle 1/49 42/18639 0.0238095238095238 9.05685131195335 0.104775698478017 0.202685131377222 GO:0001223 transcription coactivator binding 1/49 44/18639 0.0227272727272727 8.64517625231911 0.109487144122069 0.202685131377222 GO:0030547 signaling receptor inhibitor activity 1/49 44/18639 0.0227272727272727 8.64517625231911 0.109487144122069 0.202685131377222 GO:0042605 peptide antigen binding 1/49 45/18639 0.0222222222222222 8.4530612244898 0.11183374965786 0.202685131377222 GO:0030291 protein serine/threonine kinase inhibitor activity 1/49 46/18639 0.0217391304347826 8.26929902395741 0.114174297483329 0.202685131377222 GO:0005504 fatty acid binding 1/49 47/18639 0.0212765957446809 8.09335649153278 0.116508802911356 0.202685131377222 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/49 48/18639 0.0208333333333333 7.92474489795918 0.118837281216936 0.202685131377222 GO:0005004 GPI-linked ephrin receptor activity 1/49 49/18639 0.0204081632653061 7.76301541024573 0.121159747637267 0.202685131377222 GO:0005008 hepatocyte growth factor receptor activity 1/49 49/18639 0.0204081632653061 7.76301541024573 0.121159747637267 0.202685131377222 GO:0005009 insulin receptor activity 1/49 49/18639 0.0204081632653061 7.76301541024573 0.121159747637267 0.202685131377222 GO:0005011 macrophage colony-stimulating factor receptor activity 1/49 49/18639 0.0204081632653061 7.76301541024573 0.121159747637267 0.202685131377222 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/49 49/18639 0.0204081632653061 7.76301541024573 0.121159747637267 0.202685131377222 GO:0005020 stem cell factor receptor activity 1/49 49/18639 0.0204081632653061 7.76301541024573 0.121159747637267 0.202685131377222 GO:0008288 boss receptor activity 1/49 49/18639 0.0204081632653061 7.76301541024573 0.121159747637267 0.202685131377222 GO:0035254 glutamate receptor binding 1/49 49/18639 0.0204081632653061 7.76301541024573 0.121159747637267 0.202685131377222 GO:0036332 placental growth factor receptor activity 1/49 49/18639 0.0204081632653061 7.76301541024573 0.121159747637267 0.202685131377222 GO:0038062 protein tyrosine kinase collagen receptor activity 1/49 49/18639 0.0204081632653061 7.76301541024573 0.121159747637267 0.202685131377222 GO:0060175 brain-derived neurotrophic factor receptor activity 1/49 49/18639 0.0204081632653061 7.76301541024573 0.121159747637267 0.202685131377222 GO:0005006 epidermal growth factor receptor activity 1/49 50/18639 0.02 7.60775510204082 0.123476217371843 0.202685131377222 GO:0005007 fibroblast growth factor receptor activity 1/49 50/18639 0.02 7.60775510204082 0.123476217371843 0.202685131377222 GO:0005017 platelet-derived growth factor receptor activity 1/49 50/18639 0.02 7.60775510204082 0.123476217371843 0.202685131377222 GO:0005019 platelet-derived growth factor beta-receptor activity 1/49 50/18639 0.02 7.60775510204082 0.123476217371843 0.202685131377222 GO:0005010 insulin-like growth factor receptor activity 1/49 51/18639 0.0196078431372549 7.45858343337335 0.125786705582547 0.202685131377222 GO:0005021 vascular endothelial growth factor receptor activity 1/49 51/18639 0.0196078431372549 7.45858343337335 0.125786705582547 0.202685131377222 GO:0005030 neurotrophin receptor activity 1/49 51/18639 0.0196078431372549 7.45858343337335 0.125786705582547 0.202685131377222 GO:0004864 protein phosphatase inhibitor activity 1/49 53/18639 0.0188679245283019 7.17712745475549 0.130389797892353 0.202685131377222 GO:0005003 ephrin receptor activity 1/49 53/18639 0.0188679245283019 7.17712745475549 0.130389797892353 0.202685131377222 GO:0005005 transmembrane-ephrin receptor activity 1/49 53/18639 0.0188679245283019 7.17712745475549 0.130389797892353 0.202685131377222 GO:0038064 collagen receptor activity 1/49 53/18639 0.0188679245283019 7.17712745475549 0.130389797892353 0.202685131377222 GO:0098632 cell-cell adhesion mediator activity 1/49 55/18639 0.0181818181818182 6.91614100185529 0.134969145112948 0.20747055647339 GO:0019212 phosphatase inhibitor activity 1/49 56/18639 0.0178571428571429 6.79263848396501 0.137249951822454 0.20747055647339 GO:0033218 amide binding 2/49 247/18639 0.00809716599190283 3.08006279434851 0.137432725307214 0.20747055647339 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/49 60/18639 0.0166666666666667 6.33979591836735 0.146314414113907 0.218774885865556 GO:0016500 protein-hormone receptor activity 1/49 67/18639 0.0149253731343284 5.67742918062748 0.161953257420965 0.237632349673752 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/49 67/18639 0.0149253731343284 5.67742918062748 0.161953257420965 0.237632349673752 GO:0004521 RNA endonuclease activity 1/49 73/18639 0.0136986301369863 5.21079116578138 0.175134338471832 0.254593436482201 GO:0098631 cell adhesion mediator activity 1/49 76/18639 0.0131578947368421 5.00510204081633 0.18164850469555 0.261640506763316 GO:0019199 transmembrane receptor protein kinase activity 1/49 78/18639 0.0128205128205128 4.87676609105181 0.185963257312367 0.265420285436742 GO:0033293 monocarboxylic acid binding 1/49 79/18639 0.0126582278481013 4.81503487470938 0.188112268701392 0.266068704379447 GO:0004860 protein kinase inhibitor activity 1/49 84/18639 0.0119047619047619 4.52842565597668 0.198774239800552 0.278638889720416 GO:0019210 kinase inhibitor activity 1/49 90/18639 0.0111111111111111 4.2265306122449 0.211387659242787 0.293697898239978 GO:0043178 alcohol binding 1/49 92/18639 0.0108695652173913 4.1346495119787 0.215548746553123 0.296852221130178 GO:0016410 N-acyltransferase activity 1/49 94/18639 0.0106382978723404 4.04667824576639 0.219688323783251 0.299922320295394 GO:0004896 cytokine receptor activity 1/49 96/18639 0.0104166666666667 3.96237244897959 0.223806499821325 0.302910521309897 GO:0005200 structural constituent of cytoskeleton 1/49 112/18639 0.00892857142857143 3.39631924198251 0.255994354944207 0.342629324273275 GO:0001221 transcription coregulator binding 1/49 115/18639 0.00869565217391304 3.30771960958296 0.261882286068745 0.342629324273275 GO:0035401 histone H3Y41 kinase activity 1/49 115/18639 0.00869565217391304 3.30771960958296 0.261882286068745 0.342629324273275 GO:0140801 histone H2AXY142 kinase activity 1/49 115/18639 0.00869565217391304 3.30771960958296 0.261882286068745 0.342629324273275 GO:0004540 RNA nuclease activity 1/49 121/18639 0.00826446280991736 3.14370045538877 0.273521537471711 0.351990831008677 GO:0051082 unfolded protein binding 1/49 121/18639 0.00826446280991736 3.14370045538877 0.273521537471711 0.351990831008677 GO:0004519 endonuclease activity 1/49 127/18639 0.0078740157480315 2.99517917403182 0.284980939226151 0.363756158199234 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/49 130/18639 0.00769230769230769 2.92605965463108 0.290644048697807 0.36799286810932 GO:0005179 hormone activity 1/49 132/18639 0.00757575757575758 2.8817254174397 0.294395020557148 0.369760145819778 GO:0051087 protein-folding chaperone binding 1/49 134/18639 0.00746268656716418 2.83871459031374 0.29812656050883 0.371475158729256 GO:0004713 protein tyrosine kinase activity 1/49 140/18639 0.00714285714285714 2.71705539358601 0.309205572276697 0.382246258641271 GO:0019955 cytokine binding 1/49 144/18639 0.00694444444444444 2.64158163265306 0.316496214882969 0.388202388567391 GO:0019842 vitamin binding 1/49 150/18639 0.00666666666666667 2.53591836734694 0.327291058891929 0.398330978651417 GO:0140375 immune receptor activity 1/49 156/18639 0.00641025641025641 2.4383830455259 0.33791884109951 0.408101985020177 GO:0016874 ligase activity 1/49 167/18639 0.00598802395209581 2.27777098863498 0.356977590115219 0.427828104183888 GO:0003823 antigen binding 1/49 174/18639 0.00574712643678161 2.18613652357495 0.368824953689725 0.438678164615809 GO:0031406 carboxylic acid binding 1/49 187/18639 0.0053475935828877 2.03415911819273 0.390262560024038 0.46068587912612 GO:0043177 organic acid binding 1/49 189/18639 0.00529100529100529 2.01263362487852 0.393496710479263 0.461037190636151 GO:0016829 lyase activity 1/49 200/18639 0.005 1.9019387755102 0.410986410110181 0.477961973239248 GO:0005516 calmodulin binding 1/49 207/18639 0.00483091787439614 1.83762200532387 0.421857958987793 0.486961107274222 GO:0004518 nuclease activity 1/49 209/18639 0.00478468899521531 1.82003710575139 0.424927845201073 0.486961107274222 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/49 229/18639 0.00436681222707424 1.66108190000891 0.454761653402362 0.517373765102687 GO:0019887 protein kinase regulator activity 1/49 255/18639 0.00392156862745098 1.49171668667467 0.491287970555416 0.554907995519427 GO:0005126 cytokine receptor binding 1/49 275/18639 0.00363636363636364 1.38322820037106 0.517743530269568 0.580612387516587 GO:0030246 carbohydrate binding 1/49 280/18639 0.00357142857142857 1.358527696793 0.524143918120651 0.58362124216271 GO:0019207 kinase regulator activity 1/49 287/18639 0.00348432055749129 1.32539287492 0.532964866976393 0.589263972642914 GO:0001664 G protein-coupled receptor binding 1/49 297/18639 0.00336700336700337 1.28076685219542 0.54528896746104 0.598673901338345 GO:0031625 ubiquitin protein ligase binding 1/49 302/18639 0.0033112582781457 1.25956210298689 0.551330979584216 0.601103915241124 GO:0044389 ubiquitin-like protein ligase binding 1/49 322/18639 0.0031055900621118 1.18132843199392 0.574722330614551 0.622285557975755 GO:0005261 monoatomic cation channel activity 1/49 341/18639 0.00293255131964809 1.11550661320247 0.595835476417804 0.640727190394487 GO:0141003 histone H2AX kinase activity 1/49 354/18639 0.00282485875706215 1.07454168107921 0.609686080429633 0.644663764315645 GO:0045182 translation regulator activity 1/49 356/18639 0.00280898876404494 1.06850493006191 0.611775254905045 0.644663764315645 GO:0140996 histone H3 kinase activity 1/49 357/18639 0.00280112044817927 1.06551191905334 0.612815730347241 0.644663764315645 GO:0035173 histone kinase activity 1/49 360/18639 0.00277777777777778 1.05663265306122 0.615920793932144 0.644663764315645 GO:0005525 GTP binding 1/49 378/18639 0.00264550264550265 1.00631681243926 0.634045356043074 0.659239211250083 GO:0140098 catalytic activity, acting on RNA 1/49 387/18639 0.00258397932816537 0.982914095870907 0.64279072663445 0.663935158431636 GO:0019001 guanyl nucleotide binding 1/49 400/18639 0.0025 0.950969387755102 0.655062553960981 0.667823512804377 GO:0032561 guanyl ribonucleotide binding 1/49 400/18639 0.0025 0.950969387755102 0.655062553960981 0.667823512804377 GO:0003779 actin binding 1/49 443/18639 0.00225733634311512 0.858663104067812 0.692783604941078 0.701365647838614 GO:0005216 monoatomic ion channel activity 1/49 448/18639 0.00223214285714286 0.849079810495627 0.696898350718623 0.701365647838614 GO:0016755 aminoacyltransferase activity 1/49 496/18639 0.00201612903225806 0.766910796576695 0.733751176953787 0.733751176953787