category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	22/134	238/9376	6.46782892261382	RPL13A/C1QB/C1QA/RPS26/CFD/RPL10/RPL8/RPL7/RPS20/RPS11/RPL13/RPLP0/C1QC/RPL18A/RPL28/RPS9/VWF/RPS16/RPL18/RPS15/CSF3/CYBB	10.2880454660434
Genetic Information Processing	Translation	hsa03010	Ribosome	16/134	222/9376	5.04289363990857	RPL13A/RPS26/RPL10/RPL8/RPL7/RPS20/RPS11/RPL13/RPLP0/RPL18A/RPL28/RPS9/RPS16/RPL18/RPS15/RACK1	7.34037765620119
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	9/134	88/9376	7.15603799185889	SERPINE2/C1QB/C1QA/CFD/CLU/C1QC/F2R/VWF/SERPING1	6.98612865759539
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	13/134	205/9376	4.43713141609028	MT-CO2/MT-CO3/MT-CYB/CTSD/MT-ND3/MT-ND2/MT-CO1/MT-ND4/MT-ATP6/MT-ND1/CYBA/MMP2/CYBB	5.99128220492053
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	9/134	99/9376	6.36092265943012	C1QB/KRT19/KRT18/C1QA/HLA-DRA/CFD/HLA-DRB5/C1QC/HLA-DPB1	6.45666741171164
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	14/134	275/9376	3.56211668928087	C1QB/MT-CO2/C1QA/MT-CO3/MT-CYB/MT-ND3/MT-ND2/MT-CO1/MT-ND4/MT-ATP6/MT-ND1/CYBA/C1QC/CYBB	5.19249097575894
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	13/134	250/9376	3.63844776119403	PSAP/HEXB/CTSD/CTSL/CD68/CD63/CTSB/NPC2/LAPTM5/TPP1/ACP5/CTSZ/CTSK	5.09135438635005
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	8/134	95/9376	5.89222309505106	HLA-DRA/FLT1/HLA-DRB5/CTSL/HLA-DPB1/ACP5/VEGFA/CTSK	5.7706631640417
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	9/134	138/9376	4.56327060350422	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND2/MT-CO1/MT-ND4/MT-ATP6/MT-ND1	5.07755252319766
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	7/134	82/9376	5.97306152165999	CD74/HLA-DRA/HLA-DRB5/CTSL/CTSB/HLA-DPB1/HLA-G	5.4460858025691
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	5/134	42/9376	8.32977967306326	FTL/FTH1/GPX4/SLC40A1/CYBB	5.73240310447584
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	9/134	155/9376	4.06278285989408	HLA-DRA/HLA-DRB5/CTSL/CD14/CYBA/ACTB/HLA-DPB1/HLA-G/CYBB	4.62964937778207
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	11/134	227/9376	3.39062397264777	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND2/MT-CO1/MT-ND4/MT-ATP6/MT-ND1/CYBA/VEGFA	4.39028223463917
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	7/134	100/9376	4.89791044776119	HLA-DRA/HLA-DRB5/CD14/HLA-DPB1/IL1R2/CSF3/CD44	4.71852806541102
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	10/134	204/9376	3.42990927714369	FN1/TIMP3/LUM/DCN/CTSL/CD63/ACTB/VEGFA/MMP2/CD44	4.22501422116466
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	5/134	52/9376	6.72789896670494	APOE/LRPAP1/NPC2/PLTP/APOC1	4.98713292196349
Human Diseases	Immune disease	hsa05310	Asthma	4/134	32/9376	8.74626865671642	HLA-DRA/PRG2/HLA-DRB5/HLA-DPB1	5.28513621205097
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	12/134	298/9376	2.81758990283482	PRL/IL1RL1/EBI3/CCL4/CXCL14/PRLR/IL1R2/CSH1/CCL18/CXCR4/CCL4L2/CSF3	3.83940564908064
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	7/134	116/9376	4.22233659289758	MYL9/THY1/CYBA/ACTB/MMP2/CXCR4/CYBB	4.20483985291532
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	10/134	235/9376	2.97745315973325	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND2/MT-CO1/MT-ND4/MT-ATP6/MT-ND1/ACTB	3.69656491362815
Human Diseases	Immune disease	hsa05330	Allograft rejection	4/134	39/9376	7.17642556448527	HLA-DRA/HLA-DRB5/HLA-DPB1/HLA-G	4.65394119306805
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	5/134	70/9376	4.99786780383795	HLA-DRA/HLA-DRB5/ACTB/HLA-DPB1/HLA-G	4.04250886113392
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	4/134	44/9376	6.36092265943012	HLA-DRA/HLA-DRB5/HLA-DPB1/HLA-G	4.29174164449138
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	13/134	388/9376	2.34436067087244	APOE/MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND2/MT-CO1/MT-ND4/MT-ATP6/MT-ND1/DKK1/IRS2/CYBB	3.25653076181969
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	4/134	45/9376	6.2195688225539	HLA-DRA/HLA-DRB5/HLA-DPB1/HLA-G	4.22602289734784
NA	NA	hsa04382	Cornified envelope formation	9/134	217/9376	2.9019877570672	KRT8/KRT19/KRT18/KRT7/S100A4/S100A9/S100A6/S100A8/S100A11	3.41325401533247
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	5/134	78/9376	4.48526597780329	C1QB/C1QA/CD14/C1QC/SERPING1	3.72171842544471
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	5/134	78/9376	4.48526597780329	HLA-DRA/HLA-DRB5/CYBA/HLA-DPB1/CYBB	3.72171842544471
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	4/134	50/9376	5.59761194029851	HLA-DRA/HLA-DRB5/HLA-DPB1/CXCR4	3.92486446327979
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	4/134	54/9376	5.18297401879491	HLA-DRA/HLA-DRB5/HLA-DPB1/HLA-G	3.71178278334785
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	5/134	87/9376	4.02127294561674	MT-CO2/MT-CO3/MT-CYB/TPM1/MT-CO1	3.40894631517353
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	6/134	137/9376	3.06438609870356	CTSD/CTSL/CTSB/ACTB/CTSZ/CTSK	2.93085127744752
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	5/134	100/9376	3.49850746268657	CCL4/CXCL14/CCL18/CXCR4/CCL4L2	3.02451216935903
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	9/134	268/9376	2.34974381822232	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND2/MT-CO1/MT-ND4/MT-ATP6/MT-ND1	2.69936920113731
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	7/134	181/9376	2.70602787169127	CD74/HLA-DRA/HLA-DRB5/CTSD/CD14/HLA-DPB1/CEBPB	2.79064503145046
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	6/134	142/9376	2.95648517973513	CTSL/CYBA/ACTB/IL1R2/VEGFA/MMP2	2.82866068853554
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	6/134	143/9376	2.93581045819852	C1QB/C1QA/HLA-DRA/HLA-DRB5/C1QC/HLA-DPB1	2.8087590712781
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	5/134	109/9376	3.20963987402437	SPP1/CD14/CCL4/CTSK/CCL4L2	2.79396023743661
NA	NA	hsa04518	Integrin signaling	6/134	154/9376	2.72610971118434	FN1/SPP1/FLT1/ACTB/VWF/VEGFA	2.60058619435411
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	7/134	201/9376	2.43677136704537	IGFBP3/HPGD/FLT1/CD14/NUPR1/CEBPB/IL1R2	2.47934927673493
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	7/134	203/9376	2.41276376737005	FN1/SPP1/FLT1/MYL9/ACTB/VWF/VEGFA	2.45028682960416
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	6/134	160/9376	2.62388059701493	HLA-DRA/HLA-DRB5/HLA-DPB1/HLA-G/VCAN/PTPRC	2.49458270038352
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	9/134	308/9376	2.04458228338825	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND2/MT-CO1/MT-ND4/MT-ATP6/MT-ND1	2.24448813291486
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	3/134	50/9376	4.19820895522388	CD81/HBB/CSF3	2.7302297013102
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	10/134	362/9376	1.93287705120805	FN1/SPP1/PRL/FLT1/PRLR/F2R/VWF/VEGFA/CSH1/CSF3	2.17959083591311
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	10/134	368/9376	1.90136275146009	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND2/MT-CO1/MT-ND4/MT-ATP6/MT-ND1/ACTB	2.1240482740324
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	4/134	89/9376	3.14472580915646	FN1/SPP1/VWF/CD44	2.44784612433445
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	4/134	94/9376	2.97745315973325	S100A9/S100A8/CEBPB/CSF3	2.32008771855521
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	7/134	233/9376	2.10210748830953	FN1/DCN/FBLN1/MYL9/TPM1/ACTB/VCAN	2.05122173239655
Organismal Systems	Digestive system	hsa04978	Mineral absorption	3/134	61/9376	3.44115488133105	FTL/FTH1/SLC40A1	2.30315877143501
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/134	101/9376	2.77109501994976	FN1/VEGFA/MMP2/CYBB	2.15476863318068
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	3/134	63/9376	3.3319118692253	HPGD/PTGDS/GPX4	2.23610741368856
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	3/134	66/9376	3.18046132971506	HLA-DRA/HLA-DRB5/HLA-DPB1	2.14042774329648
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	4/134	109/9376	2.5677118992195	HLA-DRA/HLA-DRB5/EBI3/HLA-DPB1	1.98227990075056
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	4/134	110/9376	2.54436906377205	FLT1/TIMP1/VEGFA/CYBB	1.96180728696107
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	5/134	157/9376	2.22834870234813	C1QB/C1QA/MFGE8/C1QC/CEBPB	1.86889389514223
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	5/134	157/9376	2.22834870234813	MT-CO2/MT-CO3/MT-CYB/MT-CO1/IRS2	1.86889389514223
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	11/134	480/9376	1.60348258706468	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND2/MT-CO1/MT-ND4/MT-ATP6/MT-ND1/DKK1/CYBB	1.63434233408185
NA	NA	hsa04081	Hormone signaling	6/134	219/9376	1.91699039051319	PRL/RAMP1/PRLR/SLC40A1/IRS2/CSH1	1.65335186716972
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	6/134	232/9376	1.80957282552753	FN1/MYL9/RGCC/ACTB/F2R/CXCR4	1.50344263205985
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	5/134	180/9376	1.94361525704809	CD74/HLA-DRA/HLA-DRB5/HLA-DPB1/HLA-G	1.53917067644613
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	2/134	41/9376	3.41317801237714	VEGFA/MMP2	1.8645721026407
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	4/134	134/9376	2.08866117175317	MYL9/RAMP1/CALD1/MYL6	1.52833023905432
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	4/134	139/9376	2.01352947492752	KRT19/KRT18/CTSD/MMP2	1.44955055563293
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/134	46/9376	3.04218040233614	FTL/FTH1	1.6718112888089
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	5/134	193/9376	1.81269816719511	CCL4/CXCL14/CCL18/CXCR4/CCL4L2	1.37363294384762
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	4/134	142/9376	1.97099011982342	TYROBP/CYBA/ACP5/CTSK	1.40384481791616
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/134	93/9376	2.25710158883004	HLA-DRA/HLA-DRB5/HLA-DPB1	1.46697505713157
NA	NA	hsa03272	Virion - Hepatitis viruses	2/134	48/9376	2.91542288557214	CD63/CD81	1.60193937893746
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	4/134	144/9376	1.94361525704809	C1QB/C1QA/CD14/C1QC	1.37398932226526
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	4/134	149/9376	1.87839326855655	MT-ND3/MT-ND2/MT-ND4/MT-ND1	1.30138839055818
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	5/134	205/9376	1.70658900618857	HLA-DRA/HLA-DRB5/HLA-DPB1/HLA-G/CD44	1.23165908616479
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/134	103/9376	2.0379655122446	C1QB/C1QA/C1QC	1.2754001434687
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	3/134	103/9376	2.0379655122446	FN1/CD14/IL1R2	1.2754001434687
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	2/134	55/9376	2.54436906377205	PSAP/HEXB	1.38310846542289
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	3/134	105/9376	1.99914712153518	CD14/CCL4/CCL4L2	1.23969787232998
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/134	15/9376	4.66467661691542	HEXB	1.71031151339057
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	1/134	16/9376	4.37313432835821	MIF	1.62596337446889
Metabolism	Glycan biosynthesis and metabolism	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	1/134	16/9376	4.37313432835821	HEXB	1.62596337446889
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/134	112/9376	1.87420042643923	HLA-DRA/HLA-DRB5/HLA-DPB1	1.12066499727194
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	5/134	224/9376	1.56183368869936	HLA-DRA/HLA-DRB5/HLA-DPB1/HLA-G/IL1R2	1.02477573992225
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	4/134	168/9376	1.66595593461265	PRL/PRLR/CSH1/CSF3	1.04875135341818
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/134	62/9376	2.25710158883004	CRYAB/IRS2	1.19578515757067
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	4/134	169/9376	1.65609820718891	CTSD/CTSL/CTSB/IRS2	1.03635414096675
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	5/134	227/9376	1.5411927148399	CCL4/HLA-G/VEGFA/CXCR4/CCL4L2	0.993878078971233
Metabolism	Glycan biosynthesis and metabolism	hsa00511	Other glycan degradation	1/134	18/9376	3.88723051409619	HEXB	1.47632252614446
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	4/134	173/9376	1.61780691916142	HLA-DRA/HLA-DRB5/ACTB/HLA-DPB1	0.987566077646908
Metabolism	Glycan biosynthesis and metabolism	hsa00531	Glycosaminoglycan degradation	1/134	19/9376	3.68263943440691	HEXB	1.40937266940798
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/134	122/9376	1.72057744066552	IGFBP3/IRS2/CSH1	0.964608055583299
Organismal Systems	Immune system	hsa04611	Platelet activation	3/134	126/9376	1.66595593461265	ACTB/F2R/VWF	0.906181006043429
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/134	71/9376	1.97099011982342	PRL/PRLR	0.988873757282595
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/134	22/9376	3.18046132971506	AOC1	1.23286664171782
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	5/134	248/9376	1.41068849301878	MYL9/CD14/ACTB/AHNAK/PTPRC	0.789233688068581
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/134	75/9376	1.86587064676617	IGFBP3/CD82	0.906512677407034
Cellular Processes	Cell motility	hsa04814	Motor proteins	4/134	194/9376	1.44268348976766	MYL9/TPM1/ACTB/MYL6	0.750206117004412
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	4/134	195/9376	1.43528511289705	CYBA/ACTB/VWF/CYBB	0.739607287100905
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/134	78/9376	1.79410639112132	FN1/ACTB	0.847981303700205
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	2/134	83/9376	1.686027692861	CCL4/CCL4L2	0.755888573156868
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	4/134	212/9376	1.32019149535342	FLT1/ACTB/F2R/VEGFA	0.567793266488191
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/134	154/9376	1.36305485559217	MYL9/ACTB/MYL6	0.546984608874255
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/134	93/9376	1.50473439255336	MYL9/ACTB	0.588999943148066
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/134	93/9376	1.50473439255336	MMP14/MMP2	0.588999943148066
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/134	37/9376	1.89108511496571	MIF	0.65392044924189
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/134	37/9376	1.89108511496571	HBB	0.65392044924189
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	2/134	99/9376	1.41353836876225	TPM1/ACTB	0.498063463829833
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/134	38/9376	1.84131971720346	HEXB	0.625721367798082
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	1/134	38/9376	1.84131971720346	PTPRC	0.625721367798082
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	3/134	168/9376	1.24946695095949	FTL/FTH1/CYBB	0.39286203313744
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	6/134	370/9376	1.13465106897943	PRL/NPW/TAC3/PRLR/F2R/CSH1	0.31819968954483
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/134	170/9376	1.23476733977173	MYL9/ACTB/MYL6	0.37194755614092
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/134	105/9376	1.33276474769012	TPM1/ACTB	0.412879886061243
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/134	42/9376	1.66595593461265	AOC1	0.520824368165797
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/134	110/9376	1.27218453188602	DCN/EMP3	0.345755176387622
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/134	44/9376	1.59023066485753	HEXB	0.472515215224943
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	4/134	253/9376	1.10624741903133	MYL9/CD14/ACTB/CD44	0.206283678567834
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/134	47/9376	1.48872657986662	IRS2	0.404438412394522
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	5/134	323/9376	1.0831292454138	TIMP3/TPM1/IRS2/VEGFA/CD44	0.183068614441667
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	4/134	254/9376	1.10189211423199	FLT1/F2R/VEGFA/CXCR4	0.198229120210451
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	3/134	187/9376	1.12251576342885	CTSB/CYBA/CYBB	0.203766930493285
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/134	119/9376	1.17596889502069	CEBPB/MMP14	0.232610497986466
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/134	50/9376	1.39940298507463	AOC1	0.340960177371014
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	5/134	333/9376	1.05060284164762	FN1/SPP1/HLA-G/VWF/VEGFA	0.113212873189654
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/134	51/9376	1.37196371085748	ACTB	0.320712801041836
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/134	56/9376	1.24946695095949	CD14	0.225452020418441
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/134	130/9376	1.07646383467279	VEGFA/MMP2	0.105707514420178
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/134	133/9376	1.05218269554483	TYROBP/HLA-G	0.0729795041833451
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/134	59/9376	1.18593473311409	GPX4	0.17250573508798
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/134	59/9376	1.18593473311409	IRS2	0.17250573508798
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/134	60/9376	1.16616915422886	VEGFA	0.155477070817088
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/134	138/9376	1.01406013411205	FN1/ACTB	0.0200352646153007
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	3/134	216/9376	0.971807628524046	CD14/CYBA/CYBB	-0.0504737768440463
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/134	65/9376	1.07646383467279	SPP1	0.0744851410395391
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/134	66/9376	1.06015377657169	HSD11B1	0.059049344504964
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/134	68/9376	1.02897278314311	CD14	0.0288716457345791
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/134	69/9376	1.01406013411205	CTSB	0.0141144580377313
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/134	226/9376	0.928807290978735	MYL9/F2R/FXYD1	-0.130447045391328
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/134	70/9376	0.999573560767591	IRS2	-0.000431200945187652
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/134	70/9376	0.999573560767591	HSD11B1	-0.000431200945187652
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/134	70/9376	0.999573560767591	VEGFA	-0.000431200945187652
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/134	71/9376	0.985495059911709	SLC16A3	-0.0147720911999348
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/134	73/9376	0.958495195256594	CXCR4	-0.0428650515119054
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	2/134	157/9376	0.891339480939253	IGFBP3/HLA-G	-0.165323560262175
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/134	76/9376	0.920659858601728	PLTP	-0.0836206130697797
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/134	76/9376	0.920659858601728	ACTB	-0.0836206130697797
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/134	77/9376	0.908703237061446	VEGFA	-0.096858485329326
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/134	79/9376	0.885698091819384	HSD11B1	-0.122843071316948
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/134	80/9376	0.874626865671642	VEGFA	-0.135598996211819
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	2/134	166/9376	0.843013846430498	MYL9/IRS2	-0.245720071399288
NA	NA	hsa04519	Cadherin signaling	5/134	404/9376	0.865967193734299	KRT8/KRT19/KRT18/KRT7/ACTB	-0.331598239355934
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/134	250/9376	0.839641791044776	RAB31/HLA-G/CXCR4	-0.309439695020506
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/134	86/9376	0.813606386671295	ACTB	-0.209087202190783
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	2/134	174/9376	0.804254589123349	CRYAB/SSR4	-0.313819664713935
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	2/134	178/9376	0.786181452289116	NOTUM/DKK1	-0.346787735052587
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/134	90/9376	0.777446102819237	IRS2	-0.25544486335335
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/134	91/9376	0.768902739051993	CD81	-0.266734747894009
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/134	93/9376	0.752367196276681	LYZ	-0.288975170835442
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/134	93/9376	0.752367196276681	FN1	-0.288975170835442
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	2/134	184/9376	0.760545100584036	MYL9/CXCR4	-0.394986894718313
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/134	98/9376	0.713981114833993	PTPRC	-0.342716977150453
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/134	99/9376	0.706769184381125	MMP2	-0.353165671581854
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/134	196/9376	0.713981114833993	HLA-G/VEGFA	-0.487255174519561
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	2/134	200/9376	0.699701492537314	ACTB/F2R	-0.516888088781403
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/134	106/9376	0.660095747676711	IL1R2	-0.423764643314638
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/134	109/9376	0.641927974804875	IRS2	-0.4527611093076
NA	NA	hsa04517	IgSF CAM signaling	3/134	299/9376	0.702041631308341	MYL9/ACTB/MYL6	-0.630485451428175
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	3/134	300/9376	0.699701492537314	FLT1/CD14/VEGFA	-0.636534009665693
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/134	115/9376	0.608436080467229	MMP14	-0.508718698036593
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/134	214/9376	0.653926628539545	HLA-G/CXCR4	-0.616644670179143
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/134	117/9376	0.598035463707106	ACTB	-0.526809602880327
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/134	122/9376	0.573525813555175	IRS2	-0.570903850893613
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/134	122/9376	0.573525813555175	PTPRC	-0.570903850893613
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/134	122/9376	0.573525813555175	ACTB	-0.570903850893613
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/134	125/9376	0.559761194029851	CTSD	-0.596628566123063
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/134	133/9376	0.526091347772416	IRS2	-0.662779454121003
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	2/134	238/9376	0.587984447510347	FLT1/VEGFA	-0.775231777863349
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/134	136/9376	0.514486391571554	RACK1	-0.686736184316546
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/134	138/9376	0.507030067056024	IRS2	-0.702467200896465
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/134	140/9376	0.499786780383795	SPP1	-0.71801294813681
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/134	149/9376	0.469598317139137	F2R	-0.785819537918298
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/134	154/9376	0.454351618530723	TPM1	-0.822083114778979
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/134	156/9376	0.448526597780329	CD81	-0.836327668692758
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/134	157/9376	0.445669740469626	ACTB	-0.843396045396976
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/134	158/9376	0.442849045909692	CDKN1C	-0.850429125393043
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/134	170/9376	0.411589113257243	ACTB	-0.932233553199867
NA	NA	hsa04082	Neuroactive ligand signaling	1/134	199/9376	0.351608790219755	TAC3	-1.113187564473
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	1/134	205/9376	0.341317801237714	HLA-G	-1.14815247321307
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/134	217/9376	0.322443084118578	VEGFA	-1.21592468466496