ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0001968 fibronectin binding 9/190 30/18639 0.3 29.43 1.16886499473306e-11 4.99105352751019e-09 GO:0003735 structural constituent of ribosome 15/190 175/18639 0.0857142857142857 8.40857142857143 3.36153362581541e-10 7.1768742911159e-08 GO:0005201 extracellular matrix structural constituent 13/190 168/18639 0.0773809523809524 7.59107142857143 1.81549486055488e-08 2.58405435152312e-06 GO:0005518 collagen binding 9/190 72/18639 0.125 12.2625 4.81174489400541e-08 5.13653767435077e-06 GO:0043394 proteoglycan binding 7/190 37/18639 0.189189189189189 18.5594594594595 8.13937064784709e-08 6.95102253326142e-06 GO:0031994 insulin-like growth factor I binding 5/190 13/18639 0.384615384615385 37.7307692307692 1.25771319237737e-07 8.95072555241893e-06 GO:0005539 glycosaminoglycan binding 14/190 242/18639 0.0578512396694215 5.67520661157025 1.96940747734789e-07 1.20133856118221e-05 GO:0009055 electron transfer activity 10/190 116/18639 0.0862068965517241 8.45689655172414 3.06011575038232e-07 1.63333678176657e-05 GO:0050840 extracellular matrix binding 8/190 67/18639 0.119402985074627 11.7134328358209 3.92464100264748e-07 1.86202412014497e-05 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 8/190 68/18639 0.117647058823529 11.5411764705882 4.40945559904898e-07 1.88283754079391e-05 GO:0005520 insulin-like growth factor binding 5/190 19/18639 0.263157894736842 25.8157894736842 1.08119560965193e-06 4.19700477564886e-05 GO:0019838 growth factor binding 10/190 136/18639 0.0735294117647059 7.21323529411765 1.33750606013955e-06 4.7592923973299e-05 GO:0008201 heparin binding 11/190 172/18639 0.063953488372093 6.27383720930233 1.56650337744463e-06 5.14536109360661e-05 GO:0042277 peptide binding 13/190 249/18639 0.0522088353413655 5.12168674698795 1.72713638719593e-06 5.2677659809476e-05 GO:0005178 integrin binding 10/190 161/18639 0.062111801242236 6.09316770186335 6.12529308932833e-06 0.000165560975002031 GO:0004896 cytokine receptor activity 8/190 96/18639 0.0833333333333333 8.175 6.20368992981849e-06 0.000165560975002031 GO:0023026 MHC class II protein complex binding 5/190 27/18639 0.185185185185185 18.1666666666667 7.02537344319104e-06 0.000176460850602504 GO:0033218 amide binding 12/190 247/18639 0.048582995951417 4.76599190283401 9.08541445013807e-06 0.000215526220567164 GO:0008191 metalloendopeptidase inhibitor activity 4/190 14/18639 0.285714285714286 28.0285714285714 9.66778155548796e-06 0.000217270669694387 GO:0015078 proton transmembrane transporter activity 10/190 185/18639 0.0540540540540541 5.3027027027027 2.06770608391197e-05 0.000441455248915205 GO:0001540 amyloid-beta binding 7/190 83/18639 0.0843373493975904 8.27349397590361 2.21126653833911e-05 0.000449624196128953 GO:0022853 active monoatomic ion transmembrane transporter activity 8/190 118/18639 0.0677966101694915 6.65084745762712 2.82868638708382e-05 0.000549022312402178 GO:0140375 immune receptor activity 9/190 156/18639 0.0576923076923077 5.65961538461538 3.23449126651009e-05 0.000600490335130352 GO:0023023 MHC protein complex binding 5/190 37/18639 0.135135135135135 13.2567567567568 3.49243505230962e-05 0.000621362403056753 GO:0042056 chemoattractant activity 5/190 42/18639 0.119047619047619 11.6785714285714 6.54014733933679e-05 0.00108847628237412 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/190 22/18639 0.181818181818182 17.8363636363636 6.62772443600166e-05 0.00108847628237412 GO:0004857 enzyme inhibitor activity 14/190 416/18639 0.0336538461538462 3.30144230769231 9.74478582402553e-05 0.00154111983216996 GO:0005504 fatty acid binding 5/190 47/18639 0.106382978723404 10.436170212766 0.000113171596601816 0.00171088578181216 GO:0019955 cytokine binding 8/190 144/18639 0.0555555555555556 5.45 0.000116195989865463 0.00171088578181216 GO:1901681 sulfur compound binding 11/190 275/18639 0.04 3.924 0.000124951870103089 0.00177848161780064 GO:0050750 low-density lipoprotein particle receptor binding 4/190 26/18639 0.153846153846154 15.0923076923077 0.000131203445949166 0.00180722165871916 GO:0005125 cytokine activity 10/190 234/18639 0.0427350427350427 4.19230769230769 0.000148721059055987 0.00197613180233292 GO:0033293 monocarboxylic acid binding 6/190 79/18639 0.0759493670886076 7.4506329113924 0.000155440330680453 0.00197613180233292 GO:0008199 ferric iron binding 3/190 11/18639 0.272727272727273 26.7545454545455 0.000161978016584665 0.00197613180233292 GO:0050786 RAGE receptor binding 3/190 11/18639 0.272727272727273 26.7545454545455 0.000161978016584665 0.00197613180233292 GO:0048306 calcium-dependent protein binding 6/190 80/18639 0.075 7.3575 0.000166636085660577 0.00197648912714073 GO:0070325 lipoprotein particle receptor binding 4/190 31/18639 0.129032258064516 12.658064516129 0.000265367771953941 0.00306248753038738 GO:0004175 endopeptidase activity 13/190 405/18639 0.0320987654320988 3.14888888888889 0.000274271082119177 0.00307630415641256 GO:0016651 oxidoreductase activity, acting on NAD(P)H 6/190 88/18639 0.0681818181818182 6.68863636363636 0.000280973915925269 0.00307630415641256 GO:0015399 primary active transmembrane transporter activity 8/190 166/18639 0.0481927710843374 4.72771084337349 0.000307837119158331 0.00328616124701519 GO:0044548 S100 protein binding 3/190 14/18639 0.214285714285714 21.0214285714286 0.000349359641919871 0.00363845285609231 GO:0004129 cytochrome-c oxidase activity 3/190 15/18639 0.2 19.62 0.00043342995764334 0.00440653790270729 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/190 16/18639 0.1875 18.39375 0.000529460167483844 0.00510451386564905 GO:0061134 peptidase regulator activity 9/190 226/18639 0.0398230088495575 3.90663716814159 0.000532520990070311 0.00510451386564905 GO:0005126 cytokine receptor binding 10/190 275/18639 0.0363636363636364 3.56727272727273 0.000537946426122266 0.00510451386564905 GO:0008137 NADH dehydrogenase (ubiquinone) activity 4/190 41/18639 0.0975609756097561 9.57073170731707 0.000788887472605063 0.00732293371309483 GO:0008307 structural constituent of muscle 4/190 42/18639 0.0952380952380952 9.34285714285714 0.000865043893574715 0.00785901579907241 GO:0003954 NADH dehydrogenase activity 4/190 44/18639 0.0909090909090909 8.91818181818182 0.00103264909910019 0.0089987992921588 GO:0030547 signaling receptor inhibitor activity 4/190 44/18639 0.0909090909090909 8.91818181818182 0.00103264909910019 0.0089987992921588 GO:0042605 peptide antigen binding 4/190 45/18639 0.0888888888888889 8.72 0.00112445513728956 0.00960284687245284 GO:0120020 cholesterol transfer activity 3/190 25/18639 0.12 11.772 0.0020327472250966 0.0169570172078483 GO:0004197 cysteine-type endopeptidase activity 5/190 88/18639 0.0568181818181818 5.57386363636364 0.00206502317285272 0.0169570172078483 GO:0008198 ferrous iron binding 3/190 26/18639 0.115384615384615 11.3192307692308 0.00228077467455062 0.0183752978496814 GO:0002020 protease binding 6/190 136/18639 0.0441176470588235 4.32794117647059 0.00272687375064013 0.0215625016948766 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 4/190 58/18639 0.0689655172413793 6.76551724137931 0.00288937399752729 0.0224320490353482 GO:0051861 glycolipid binding 3/190 29/18639 0.103448275862069 10.148275862069 0.00313435098282915 0.0238994262440723 GO:0120015 sterol transfer activity 3/190 32/18639 0.09375 9.196875 0.00416049718305267 0.03116723328357 GO:0019843 rRNA binding 4/190 65/18639 0.0615384615384615 6.03692307692308 0.00436350056904865 0.0319010211060943 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/190 10/18639 0.2 19.62 0.00440786942683739 0.0319010211060943 GO:0050998 nitric-oxide synthase binding 2/190 11/18639 0.181818181818182 17.8363636363636 0.00535140085133799 0.0371463321169997 GO:1990948 ubiquitin ligase inhibitor activity 2/190 11/18639 0.181818181818182 17.8363636363636 0.00535140085133799 0.0371463321169997 GO:0004222 metalloendopeptidase activity 5/190 110/18639 0.0454545454545455 4.45909090909091 0.00539361262588754 0.0371463321169997 GO:0004866 endopeptidase inhibitor activity 6/190 161/18639 0.0372670807453416 3.65590062111801 0.00620542651210476 0.0420590019153767 GO:0097371 MDM2/MDM4 family protein binding 2/190 12/18639 0.166666666666667 16.35 0.00637881074046029 0.0425586279090085 GO:0035325 Toll-like receptor binding 2/190 13/18639 0.153846153846154 15.0923076923077 0.00748830932436496 0.049192432023136 GO:0030414 peptidase inhibitor activity 6/190 169/18639 0.0355029585798817 3.48284023668639 0.00780383838730184 0.0504884695663316 GO:0004252 serine-type endopeptidase activity 6/190 176/18639 0.0340909090909091 3.34431818181818 0.00942928248880031 0.0599009948873951 GO:0048156 tau protein binding 3/190 43/18639 0.0697674418604651 6.84418604651163 0.00953926850665777 0.0599009948873951 GO:0005523 tropomyosin binding 2/190 15/18639 0.133333333333333 13.08 0.00994655031971542 0.0606739569502641 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/190 15/18639 0.133333333333333 13.08 0.00994655031971542 0.0606739569502641 GO:0008009 chemokine activity 3/190 45/18639 0.0666666666666667 6.54 0.0108072218541912 0.0649955455174597 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/190 16/18639 0.125 12.2625 0.0112918489128914 0.0660955651598517 GO:0008237 metallopeptidase activity 6/190 184/18639 0.0326086956521739 3.19891304347826 0.0115677916519343 0.0660955651598517 GO:0061135 endopeptidase regulator activity 6/190 184/18639 0.0326086956521739 3.19891304347826 0.0115677916519343 0.0660955651598517 GO:0016209 antioxidant activity 4/190 86/18639 0.0465116279069767 4.56279069767442 0.0116092913044236 0.0660955651598517 GO:0031406 carboxylic acid binding 6/190 187/18639 0.0320855614973262 3.1475935828877 0.0124514916559429 0.0687110446590146 GO:0036041 long-chain fatty acid binding 2/190 17/18639 0.117647058823529 11.5411764705882 0.012712347840895 0.0687110446590146 GO:0048038 quinone binding 2/190 17/18639 0.117647058823529 11.5411764705882 0.012712347840895 0.0687110446590146 GO:0070492 oligosaccharide binding 2/190 17/18639 0.117647058823529 11.5411764705882 0.012712347840895 0.0687110446590146 GO:0043177 organic acid binding 6/190 189/18639 0.0317460317460317 3.11428571428571 0.0130663633471208 0.0697417143652574 GO:0098641 cadherin binding involved in cell-cell adhesion 2/190 18/18639 0.111111111111111 10.9 0.0142063908849421 0.0748904803440775 GO:0008236 serine-type peptidase activity 6/190 194/18639 0.0309278350515464 3.0340206185567 0.0146961434741709 0.076527478822817 GO:0043395 heparan sulfate proteoglycan binding 2/190 19/18639 0.105263157894737 10.3263157894737 0.0157723474670318 0.0801760996240782 GO:0097001 ceramide binding 2/190 19/18639 0.105263157894737 10.3263157894737 0.0157723474670318 0.0801760996240782 GO:0017171 serine hydrolase activity 6/190 198/18639 0.0303030303030303 2.97272727272727 0.0160979874716685 0.0808687135341466 GO:0016860 intramolecular oxidoreductase activity 3/190 53/18639 0.0566037735849057 5.55283018867925 0.0168175988131131 0.0825415481976931 GO:0017046 peptide hormone binding 3/190 53/18639 0.0566037735849057 5.55283018867925 0.0168175988131131 0.0825415481976931 GO:0072542 protein phosphatase activator activity 2/190 21/18639 0.0952380952380952 9.34285714285714 0.0191136050648714 0.0927444245761374 GO:0016504 peptidase activator activity 3/190 57/18639 0.0526315789473684 5.16315789473684 0.0203961144238729 0.0973127873205638 GO:0008238 exopeptidase activity 4/190 102/18639 0.0392156862745098 3.84705882352941 0.0205108919411024 0.0973127873205638 GO:0045296 cadherin binding 8/190 334/18639 0.0239520958083832 2.3497005988024 0.0214911794152703 0.100843226487037 GO:0005212 structural constituent of eye lens 2/190 23/18639 0.0869565217391304 8.5304347826087 0.0227235757814698 0.105467031072691 GO:0019888 protein phosphatase regulator activity 4/190 107/18639 0.0373831775700935 3.66728971962617 0.0239606138551635 0.110012710926396 GO:0005540 hyaluronic acid binding 2/190 24/18639 0.0833333333333333 8.175 0.0246255148240649 0.110685208735534 GO:0050431 transforming growth factor beta binding 2/190 24/18639 0.0833333333333333 8.175 0.0246255148240649 0.110685208735534 GO:0008083 growth factor activity 5/190 162/18639 0.0308641975308642 3.02777777777778 0.0253135194691936 0.112592425139017 GO:0005507 copper ion binding 3/190 63/18639 0.0476190476190476 4.67142857142857 0.0264877847888008 0.115856878711917 GO:0019211 phosphatase activator activity 2/190 25/18639 0.08 7.848 0.0265901033109317 0.115856878711917 GO:0005200 structural constituent of cytoskeleton 4/190 112/18639 0.0357142857142857 3.50357142857143 0.0277418380243244 0.11965419026653 GO:0019865 immunoglobulin binding 2/190 26/18639 0.0769230769230769 7.54615384615385 0.0286158806972968 0.12138308155695 GO:0120013 lipid transfer activity 3/190 65/18639 0.0461538461538462 4.52769230769231 0.0287112206961404 0.12138308155695 GO:0019208 phosphatase regulator activity 4/190 117/18639 0.0341880341880342 3.35384615384615 0.0318597841082631 0.133373802100278 GO:0046625 sphingolipid binding 2/190 28/18639 0.0714285714285714 7.00714285714286 0.0328452746281058 0.135563460945162 GO:0003823 antigen binding 5/190 174/18639 0.028735632183908 2.81896551724138 0.0330177984503439 0.135563460945162 GO:0097110 scaffold protein binding 3/190 70/18639 0.0428571428571429 4.20428571428571 0.0346888132605743 0.141067840593002 GO:0043236 laminin binding 2/190 29/18639 0.0689655172413793 6.76551724137931 0.0350460837870152 0.14117620544392 GO:0042379 chemokine receptor binding 3/190 72/18639 0.0416666666666667 4.0875 0.0372460854628289 0.14612984567507 GO:0031210 phosphatidylcholine binding 2/190 30/18639 0.0666666666666667 6.54 0.0373024664603809 0.14612984567507 GO:0048019 receptor antagonist activity 2/190 30/18639 0.0666666666666667 6.54 0.0373024664603809 0.14612984567507 GO:0071813 lipoprotein particle binding 2/190 32/18639 0.0625 6.13125 0.0419765790842548 0.161477470891683 GO:0071814 protein-lipid complex binding 2/190 32/18639 0.0625 6.13125 0.0419765790842548 0.161477470891683 GO:0017022 myosin binding 3/190 76/18639 0.0394736842105263 3.87236842105263 0.0426418378540348 0.161941427895638 GO:0008234 cysteine-type peptidase activity 5/190 187/18639 0.0267379679144385 2.62299465240642 0.0428556940332719 0.161941427895638 GO:0022804 active transmembrane transporter activity 9/190 457/18639 0.0196936542669584 1.93194748358862 0.0450347750468339 0.168682885482439 GO:0015035 protein-disulfide reductase activity 2/190 34/18639 0.0588235294117647 5.77058823529412 0.0468570788577371 0.173982371063076 GO:0055106 ubiquitin-protein transferase regulator activity 2/190 36/18639 0.0555555555555556 5.45 0.0519337662684418 0.191169984453661 GO:0004860 protein kinase inhibitor activity 3/190 84/18639 0.0357142857142857 3.50357142857143 0.0545330762183246 0.199022423463458 GO:0005501 retinoid binding 2/190 38/18639 0.0526315789473684 5.16315789473684 0.057196766829687 0.204874655293234 GO:0019840 isoprenoid binding 2/190 38/18639 0.0526315789473684 5.16315789473684 0.057196766829687 0.204874655293234 GO:0020037 heme binding 4/190 142/18639 0.028169014084507 2.76338028169014 0.0575760155390821 0.204874655293234 GO:0000217 DNA secondary structure binding 2/190 39/18639 0.0512820512820513 5.03076923076923 0.0598951354501763 0.211365477993597 GO:0015036 disulfide oxidoreductase activity 2/190 40/18639 0.05 4.905 0.0626365222053793 0.217445487656073 GO:0050997 quaternary ammonium group binding 2/190 40/18639 0.05 4.905 0.0626365222053793 0.217445487656073 GO:0019210 kinase inhibitor activity 3/190 90/18639 0.0333333333333333 3.27 0.0643795645170602 0.221694145554715 GO:0001530 lipopolysaccharide binding 2/190 41/18639 0.0487804878048781 4.78536585365854 0.0654197802823943 0.221700366512558 GO:0042287 MHC protein binding 2/190 41/18639 0.0487804878048781 4.78536585365854 0.0654197802823943 0.221700366512558 GO:0030246 carbohydrate binding 6/190 280/18639 0.0214285714285714 2.10214285714286 0.0674669093257936 0.22589220717333 GO:0043178 alcohol binding 3/190 92/18639 0.0326086956521739 3.19891304347826 0.0678318395501546 0.22589220717333 GO:0035198 miRNA binding 2/190 42/18639 0.0476190476190476 4.67142857142857 0.0682437815582191 0.22589220717333 GO:0046906 tetrapyrrole binding 4/190 152/18639 0.0263157894736842 2.58157894736842 0.0702362718402829 0.230699139044622 GO:0042562 hormone binding 3/190 94/18639 0.0319148936170213 3.13085106382979 0.0713668814292089 0.232623346337956 GO:0004867 serine-type endopeptidase inhibitor activity 3/190 95/18639 0.0315789473684211 3.09789473684211 0.0731649902473541 0.236677657845608 GO:0019207 kinase regulator activity 6/190 287/18639 0.0209059233449477 2.05087108013937 0.0740423207184544 0.237714819148722 GO:0004180 carboxypeptidase activity 2/190 46/18639 0.0434782608695652 4.26521739130435 0.0799252959500586 0.254687323661754 GO:0048020 CCR chemokine receptor binding 2/190 50/18639 0.04 3.924 0.0921731380768483 0.286850111864709 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/190 10/18639 0.1 9.81 0.0974081176121377 0.286850111864709 GO:0003796 lysozyme activity 1/190 10/18639 0.1 9.81 0.0974081176121377 0.286850111864709 GO:0004955 prostaglandin receptor activity 1/190 10/18639 0.1 9.81 0.0974081176121377 0.286850111864709 GO:0005131 growth hormone receptor binding 1/190 10/18639 0.1 9.81 0.0974081176121377 0.286850111864709 GO:0005381 iron ion transmembrane transporter activity 1/190 10/18639 0.1 9.81 0.0974081176121377 0.286850111864709 GO:0030957 Tat protein binding 1/190 10/18639 0.1 9.81 0.0974081176121377 0.286850111864709 GO:0031720 haptoglobin binding 1/190 10/18639 0.1 9.81 0.0974081176121377 0.286850111864709 GO:0032395 MHC class II receptor activity 1/190 10/18639 0.1 9.81 0.0974081176121377 0.286850111864709 GO:0043208 glycosphingolipid binding 1/190 10/18639 0.1 9.81 0.0974081176121377 0.286850111864709 GO:0070513 death domain binding 1/190 10/18639 0.1 9.81 0.0974081176121377 0.286850111864709 GO:0005496 steroid binding 3/190 108/18639 0.0277777777777778 2.725 0.0983034771145948 0.287504004985835 GO:0004864 protein phosphatase inhibitor activity 2/190 53/18639 0.0377358490566038 3.70188679245283 0.101692151946928 0.2881271394055 GO:0015485 cholesterol binding 2/190 54/18639 0.037037037037037 3.63333333333333 0.1049235379127 0.2881271394055 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/190 54/18639 0.037037037037037 3.63333333333333 0.1049235379127 0.2881271394055 GO:0140463 chromatin-protein adaptor activity 2/190 54/18639 0.037037037037037 3.63333333333333 0.1049235379127 0.2881271394055 GO:0003953 NAD+ nucleosidase activity 1/190 11/18639 0.0909090909090909 8.91818181818182 0.106613789288218 0.2881271394055 GO:0004954 prostanoid receptor activity 1/190 11/18639 0.0909090909090909 8.91818181818182 0.106613789288218 0.2881271394055 GO:0008526 phosphatidylinositol transfer activity 1/190 11/18639 0.0909090909090909 8.91818181818182 0.106613789288218 0.2881271394055 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/190 11/18639 0.0909090909090909 8.91818181818182 0.106613789288218 0.2881271394055 GO:0042608 T cell receptor binding 1/190 11/18639 0.0909090909090909 8.91818181818182 0.106613789288218 0.2881271394055 GO:0048185 activin binding 1/190 11/18639 0.0909090909090909 8.91818181818182 0.106613789288218 0.2881271394055 GO:0097493 structural molecule activity conferring elasticity 1/190 11/18639 0.0909090909090909 8.91818181818182 0.106613789288218 0.2881271394055 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/190 11/18639 0.0909090909090909 8.91818181818182 0.106613789288218 0.2881271394055 GO:0098632 cell-cell adhesion mediator activity 2/190 55/18639 0.0363636363636364 3.56727272727273 0.10818258899474 0.288712284379712 GO:0140313 molecular sequestering activity 2/190 55/18639 0.0363636363636364 3.56727272727273 0.10818258899474 0.288712284379712 GO:0019212 phosphatase inhibitor activity 2/190 56/18639 0.0357142857142857 3.50357142857143 0.111468413024756 0.295633617152614 GO:0004601 peroxidase activity 2/190 57/18639 0.0350877192982456 3.44210526315789 0.114780132973879 0.297680889445044 GO:0004859 phospholipase inhibitor activity 1/190 12/18639 0.0833333333333333 8.175 0.115726060065286 0.297680889445044 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/190 12/18639 0.0833333333333333 8.175 0.115726060065286 0.297680889445044 GO:0070008 serine-type exopeptidase activity 1/190 12/18639 0.0833333333333333 8.175 0.115726060065286 0.297680889445044 GO:1990459 transferrin receptor binding 1/190 12/18639 0.0833333333333333 8.175 0.115726060065286 0.297680889445044 GO:0061980 regulatory RNA binding 2/190 58/18639 0.0344827586206897 3.38275862068965 0.118116886739445 0.302011440944569 GO:0019887 protein kinase regulator activity 5/190 255/18639 0.0196078431372549 1.92352941176471 0.120095742821508 0.305243346338 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/190 59/18639 0.0338983050847458 3.32542372881356 0.121477826934516 0.306929184029812 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/190 13/18639 0.0769230769230769 7.54615384615385 0.12474587262703 0.307898772322207 GO:0005172 vascular endothelial growth factor receptor binding 1/190 13/18639 0.0769230769230769 7.54615384615385 0.12474587262703 0.307898772322207 GO:0008035 high-density lipoprotein particle binding 1/190 13/18639 0.0769230769230769 7.54615384615385 0.12474587262703 0.307898772322207 GO:0039706 co-receptor binding 1/190 13/18639 0.0769230769230769 7.54615384615385 0.12474587262703 0.307898772322207 GO:0051082 unfolded protein binding 3/190 121/18639 0.0247933884297521 2.43223140495868 0.126406209853893 0.310203744871336 GO:0015026 coreceptor activity 2/190 61/18639 0.0327868852459016 3.21639344262295 0.128268949400073 0.312976236536177 GO:0005161 platelet-derived growth factor receptor binding 1/190 14/18639 0.0714285714285714 7.00714285714286 0.133674160192844 0.317104813346359 GO:0005344 oxygen carrier activity 1/190 14/18639 0.0714285714285714 7.00714285714286 0.133674160192844 0.317104813346359 GO:0019992 diacylglycerol binding 1/190 14/18639 0.0714285714285714 7.00714285714286 0.133674160192844 0.317104813346359 GO:0032036 myosin heavy chain binding 1/190 14/18639 0.0714285714285714 7.00714285714286 0.133674160192844 0.317104813346359 GO:0061783 peptidoglycan muralytic activity 1/190 14/18639 0.0714285714285714 7.00714285714286 0.133674160192844 0.317104813346359 GO:0005543 phospholipid binding 8/190 497/18639 0.0160965794768612 1.57907444668008 0.136489499570347 0.321994565284742 GO:0004953 icosanoid receptor activity 1/190 15/18639 0.0666666666666667 6.54 0.142511846612353 0.33072042664932 GO:0015929 hexosaminidase activity 1/190 15/18639 0.0666666666666667 6.54 0.142511846612353 0.33072042664932 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/190 15/18639 0.0666666666666667 6.54 0.142511846612353 0.33072042664932 GO:0008235 metalloexopeptidase activity 2/190 66/18639 0.0303030303030303 2.97272727272727 0.145613443356978 0.336091569261782 GO:0016798 hydrolase activity, acting on glycosyl bonds 3/190 130/18639 0.0230769230769231 2.26384615384615 0.147351110541146 0.336381481809639 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/190 16/18639 0.0625 6.13125 0.151259846458985 0.336381481809639 GO:0016722 oxidoreductase activity, acting on metal ions 1/190 16/18639 0.0625 6.13125 0.151259846458985 0.336381481809639 GO:0019841 retinol binding 1/190 16/18639 0.0625 6.13125 0.151259846458985 0.336381481809639 GO:0055102 lipase inhibitor activity 1/190 16/18639 0.0625 6.13125 0.151259846458985 0.336381481809639 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/190 16/18639 0.0625 6.13125 0.151259846458985 0.336381481809639 GO:0032934 sterol binding 2/190 68/18639 0.0294117647058824 2.88529411764706 0.152681880578813 0.336381481809639 GO:0051087 protein-folding chaperone binding 3/190 134/18639 0.0223880597014925 2.19626865671642 0.157001594409392 0.336381481809639 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/190 17/18639 0.0588235294117647 5.77058823529412 0.159919065122615 0.336381481809639 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/190 17/18639 0.0588235294117647 5.77058823529412 0.159919065122615 0.336381481809639 GO:0008429 phosphatidylethanolamine binding 1/190 17/18639 0.0588235294117647 5.77058823529412 0.159919065122615 0.336381481809639 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/190 17/18639 0.0588235294117647 5.77058823529412 0.159919065122615 0.336381481809639 GO:0019198 transmembrane receptor protein phosphatase activity 1/190 17/18639 0.0588235294117647 5.77058823529412 0.159919065122615 0.336381481809639 GO:0030169 low-density lipoprotein particle binding 1/190 17/18639 0.0588235294117647 5.77058823529412 0.159919065122615 0.336381481809639 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/190 17/18639 0.0588235294117647 5.77058823529412 0.159919065122615 0.336381481809639 GO:0038191 neuropilin binding 1/190 17/18639 0.0588235294117647 5.77058823529412 0.159919065122615 0.336381481809639 GO:0051787 misfolded protein binding 1/190 17/18639 0.0588235294117647 5.77058823529412 0.159919065122615 0.336381481809639 GO:0070403 NAD+ binding 1/190 17/18639 0.0588235294117647 5.77058823529412 0.159919065122615 0.336381481809639 GO:0005516 calmodulin binding 4/190 207/18639 0.0193236714975845 1.89565217391304 0.161439472496883 0.337914974294945 GO:0000400 four-way junction DNA binding 1/190 18/18639 0.0555555555555556 5.45 0.168490398901302 0.344236365219406 GO:0008525 phosphatidylcholine transporter activity 1/190 18/18639 0.0555555555555556 5.45 0.168490398901302 0.344236365219406 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/190 18/18639 0.0555555555555556 5.45 0.168490398901302 0.344236365219406 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/190 18/18639 0.0555555555555556 5.45 0.168490398901302 0.344236365219406 GO:1901611 phosphatidylglycerol binding 1/190 18/18639 0.0555555555555556 5.45 0.168490398901302 0.344236365219406 GO:0003756 protein disulfide isomerase activity 1/190 19/18639 0.0526315789473684 5.16315789473684 0.176974735092094 0.349852832797798 GO:0008301 DNA binding, bending 1/190 19/18639 0.0526315789473684 5.16315789473684 0.176974735092094 0.349852832797798 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/190 19/18639 0.0526315789473684 5.16315789473684 0.176974735092094 0.349852832797798 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/190 19/18639 0.0526315789473684 5.16315789473684 0.176974735092094 0.349852832797798 GO:0016918 retinal binding 1/190 19/18639 0.0526315789473684 5.16315789473684 0.176974735092094 0.349852832797798 GO:0030506 ankyrin binding 1/190 19/18639 0.0526315789473684 5.16315789473684 0.176974735092094 0.349852832797798 GO:0046624 sphingolipid transporter activity 1/190 19/18639 0.0526315789473684 5.16315789473684 0.176974735092094 0.349852832797798 GO:0044183 protein folding chaperone 2/190 75/18639 0.0266666666666667 2.616 0.177904674590542 0.350070488710421 GO:0098631 cell adhesion mediator activity 2/190 76/18639 0.0263157894736842 2.58157894736842 0.181560426934772 0.354721990994758 GO:0019903 protein phosphatase binding 3/190 144/18639 0.0208333333333333 2.04375 0.181930014116749 0.354721990994758 GO:0016505 peptidase activator activity involved in apoptotic process 1/190 20/18639 0.05 4.905 0.185372952080951 0.358164029586272 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/190 20/18639 0.05 4.905 0.185372952080951 0.358164029586272 GO:0001664 G protein-coupled receptor binding 5/190 297/18639 0.0168350168350168 1.65151515151515 0.187184570427524 0.360035187263751 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/190 21/18639 0.0476190476190476 4.67142857142857 0.193685919431755 0.369213783916783 GO:0036122 BMP binding 1/190 21/18639 0.0476190476190476 4.67142857142857 0.193685919431755 0.369213783916783 GO:0001618 virus receptor activity 2/190 81/18639 0.0246913580246914 2.42222222222222 0.19999564737872 0.377867882436784 GO:0030971 receptor tyrosine kinase binding 2/190 81/18639 0.0246913580246914 2.42222222222222 0.19999564737872 0.377867882436784 GO:0140272 exogenous protein binding 2/190 82/18639 0.024390243902439 2.39268292682927 0.203709905057775 0.383189997619691 GO:0005254 chloride channel activity 2/190 83/18639 0.0240963855421687 2.36385542168675 0.207431924263957 0.383313775786406 GO:0005506 iron ion binding 3/190 154/18639 0.0194805194805195 1.91103896103896 0.207832260959606 0.383313775786406 GO:0004602 glutathione peroxidase activity 1/190 23/18639 0.0434782608695652 4.26521739130435 0.210059539892316 0.383313775786406 GO:0005158 insulin receptor binding 1/190 23/18639 0.0434782608695652 4.26521739130435 0.210059539892316 0.383313775786406 GO:0016493 C-C chemokine receptor activity 1/190 23/18639 0.0434782608695652 4.26521739130435 0.210059539892316 0.383313775786406 GO:0031681 G-protein beta-subunit binding 1/190 23/18639 0.0434782608695652 4.26521739130435 0.210059539892316 0.383313775786406 GO:0099186 structural constituent of postsynapse 1/190 23/18639 0.0434782608695652 4.26521739130435 0.210059539892316 0.383313775786406 GO:0015295 solute:proton symporter activity 1/190 24/18639 0.0416666666666667 4.0875 0.218121888808328 0.390623166147098 GO:0019957 C-C chemokine binding 1/190 24/18639 0.0416666666666667 4.0875 0.218121888808328 0.390623166147098 GO:0035035 histone acetyltransferase binding 1/190 24/18639 0.0416666666666667 4.0875 0.218121888808328 0.390623166147098 GO:0070300 phosphatidic acid binding 1/190 24/18639 0.0416666666666667 4.0875 0.218121888808328 0.390623166147098 GO:0050660 flavin adenine dinucleotide binding 2/190 86/18639 0.0232558139534884 2.28139534883721 0.218639196040179 0.390623166147098 GO:0099106 ion channel regulator activity 3/190 160/18639 0.01875 1.839375 0.22375386238194 0.398095413487869 GO:0001637 G protein-coupled chemoattractant receptor activity 1/190 26/18639 0.0384615384615385 3.77307692307692 0.234001839837656 0.402898329075319 GO:0004950 chemokine receptor activity 1/190 26/18639 0.0384615384615385 3.77307692307692 0.234001839837656 0.402898329075319 GO:0030247 polysaccharide binding 1/190 26/18639 0.0384615384615385 3.77307692307692 0.234001839837656 0.402898329075319 GO:0030507 spectrin binding 1/190 26/18639 0.0384615384615385 3.77307692307692 0.234001839837656 0.402898329075319 GO:0043548 phosphatidylinositol 3-kinase binding 1/190 26/18639 0.0384615384615385 3.77307692307692 0.234001839837656 0.402898329075319 GO:0070006 metalloaminopeptidase activity 1/190 26/18639 0.0384615384615385 3.77307692307692 0.234001839837656 0.402898329075319 GO:0070412 R-SMAD binding 1/190 26/18639 0.0384615384615385 3.77307692307692 0.234001839837656 0.402898329075319 GO:0120014 phospholipid transfer activity 1/190 26/18639 0.0384615384615385 3.77307692307692 0.234001839837656 0.402898329075319 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/190 91/18639 0.021978021978022 2.15604395604396 0.23742471313495 0.407150010074794 GO:0015252 proton channel activity 1/190 27/18639 0.037037037037037 3.63333333333333 0.241821087161078 0.411384877361674 GO:0035255 ionotropic glutamate receptor binding 1/190 27/18639 0.037037037037037 3.63333333333333 0.241821087161078 0.411384877361674 GO:0016247 channel regulator activity 3/190 168/18639 0.0178571428571429 1.75178571428571 0.245336108045419 0.415708405299182 GO:0141108 transporter regulator activity 3/190 170/18639 0.0176470588235294 1.73117647058824 0.250784442814924 0.423260699928745 GO:0004181 metallocarboxypeptidase activity 1/190 29/18639 0.0344827586206897 3.38275862068965 0.257222176651231 0.430721056588531 GO:0004629 phospholipase C activity 1/190 29/18639 0.0344827586206897 3.38275862068965 0.257222176651231 0.430721056588531 GO:0001965 G-protein alpha-subunit binding 1/190 30/18639 0.0333333333333333 3.27 0.264805614933674 0.439968862166065 GO:0098918 structural constituent of synapse 1/190 30/18639 0.0333333333333333 3.27 0.264805614933674 0.439968862166065 GO:0005319 lipid transporter activity 3/190 178/18639 0.0168539325842697 1.65337078651685 0.27274414892442 0.451402137948556 GO:0016853 isomerase activity 3/190 180/18639 0.0166666666666667 1.635 0.278268478409168 0.45876695089079 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/190 32/18639 0.03125 3.065625 0.279742208897616 0.459422781535701 GO:0005253 monoatomic anion channel activity 2/190 103/18639 0.0194174757281553 1.90485436893204 0.282739948230801 0.462566888484874 GO:0019956 chemokine binding 1/190 33/18639 0.0303030303030303 2.97272727272727 0.287096913057849 0.462605214625289 GO:0030296 protein tyrosine kinase activator activity 1/190 33/18639 0.0303030303030303 2.97272727272727 0.287096913057849 0.462605214625289 GO:0071889 14-3-3 protein binding 1/190 33/18639 0.0303030303030303 2.97272727272727 0.287096913057849 0.462605214625289 GO:0140311 protein sequestering activity 1/190 33/18639 0.0303030303030303 2.97272727272727 0.287096913057849 0.462605214625289 GO:0019825 oxygen binding 1/190 34/18639 0.0294117647058824 2.88529411764706 0.29437690803361 0.469025894516237 GO:0030332 cyclin binding 1/190 34/18639 0.0294117647058824 2.88529411764706 0.29437690803361 0.469025894516237 GO:0051427 hormone receptor binding 1/190 34/18639 0.0294117647058824 2.88529411764706 0.29437690803361 0.469025894516237 GO:0003779 actin binding 6/190 443/18639 0.0135440180586907 1.32866817155756 0.298306871088108 0.473520572322016 GO:0016229 steroid dehydrogenase activity 1/190 35/18639 0.0285714285714286 2.80285714285714 0.301582948747053 0.476947848574044 GO:0019902 phosphatase binding 3/190 190/18639 0.0157894736842105 1.54894736842105 0.30602771075292 0.482191263806261 GO:0004190 aspartic-type endopeptidase activity 1/190 36/18639 0.0277777777777778 2.725 0.308715782532157 0.482863147037476 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/190 36/18639 0.0277777777777778 2.725 0.308715782532157 0.482863147037476 GO:0030280 structural constituent of skin epidermis 1/190 37/18639 0.027027027027027 2.65135135135135 0.31577614921059 0.49031423895608 GO:0070001 aspartic-type peptidase activity 1/190 37/18639 0.027027027027027 2.65135135135135 0.31577614921059 0.49031423895608 GO:0000146 microfilament motor activity 1/190 38/18639 0.0263157894736842 2.58157894736842 0.32276478116683 0.499349860718248 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/190 39/18639 0.0256410256410256 2.51538461538462 0.329682403422532 0.508210780727151 GO:1990782 protein tyrosine kinase binding 2/190 117/18639 0.0170940170940171 1.67692307692308 0.335282166933447 0.50956807196537 GO:0004177 aminopeptidase activity 1/190 40/18639 0.025 2.4525 0.336529733710151 0.50956807196537 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/190 40/18639 0.025 2.4525 0.336529733710151 0.50956807196537 GO:0071855 neuropeptide receptor binding 1/190 40/18639 0.025 2.4525 0.336529733710151 0.50956807196537 GO:0071949 FAD binding 1/190 40/18639 0.025 2.4525 0.336529733710151 0.50956807196537 GO:0017080 sodium channel regulator activity 1/190 41/18639 0.024390243902439 2.39268292682927 0.343307482545845 0.516170052982662 GO:0042169 SH2 domain binding 1/190 41/18639 0.024390243902439 2.39268292682927 0.343307482545845 0.516170052982662 GO:0019894 kinesin binding 1/190 42/18639 0.0238095238095238 2.33571428571429 0.350016353301641 0.520898940974177 GO:0031492 nucleosomal DNA binding 1/190 42/18639 0.0238095238095238 2.33571428571429 0.350016353301641 0.520898940974177 GO:0015108 chloride transmembrane transporter activity 2/190 121/18639 0.0165289256198347 1.62148760330579 0.350112402949856 0.520898940974177 GO:0008528 G protein-coupled peptide receptor activity 2/190 122/18639 0.0163934426229508 1.60819672131148 0.353802987353724 0.522746974394602 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/190 122/18639 0.0163934426229508 1.60819672131148 0.353802987353724 0.522746974394602 GO:0008200 ion channel inhibitor activity 1/190 43/18639 0.0232558139534884 2.28139534883721 0.356657042276889 0.523342120454404 GO:0008375 acetylglucosaminyltransferase activity 1/190 43/18639 0.0232558139534884 2.28139534883721 0.356657042276889 0.523342120454404 GO:0051015 actin filament binding 3/190 209/18639 0.0143540669856459 1.40813397129187 0.358952061260469 0.524905925199384 GO:0001046 core promoter sequence-specific DNA binding 1/190 44/18639 0.0227272727272727 2.22954545454545 0.363230238769005 0.525760379506322 GO:0001223 transcription coactivator binding 1/190 44/18639 0.0227272727272727 2.22954545454545 0.363230238769005 0.525760379506322 GO:0016248 channel inhibitor activity 1/190 44/18639 0.0227272727272727 2.22954545454545 0.363230238769005 0.525760379506322 GO:0046915 transition metal ion transmembrane transporter activity 1/190 45/18639 0.0222222222222222 2.18 0.369736625143508 0.531574205172653 GO:0141110 transporter inhibitor activity 1/190 45/18639 0.0222222222222222 2.18 0.369736625143508 0.531574205172653 GO:0001653 peptide receptor activity 2/190 128/18639 0.015625 1.5328125 0.375785614927372 0.532211019293144 GO:0031490 chromatin DNA binding 2/190 128/18639 0.015625 1.5328125 0.375785614927372 0.532211019293144 GO:0030291 protein serine/threonine kinase inhibitor activity 1/190 46/18639 0.0217391304347826 2.13260869565217 0.376176876903363 0.532211019293144 GO:0035591 signaling adaptor activity 2/190 129/18639 0.0155038759689922 1.52093023255814 0.379420508511852 0.532211019293144 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/190 48/18639 0.0208333333333333 2.04375 0.38886164468943 0.532211019293144 GO:0038187 pattern recognition receptor activity 1/190 48/18639 0.0208333333333333 2.04375 0.38886164468943 0.532211019293144 GO:0140693 molecular condensate scaffold activity 1/190 48/18639 0.0208333333333333 2.04375 0.38886164468943 0.532211019293144 GO:0005179 hormone activity 2/190 132/18639 0.0151515151515152 1.48636363636364 0.390271546610395 0.532211019293144 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/190 132/18639 0.0151515151515152 1.48636363636364 0.390271546610395 0.532211019293144 GO:0005004 GPI-linked ephrin receptor activity 1/190 49/18639 0.0204081632653061 2.00204081632653 0.395107478023248 0.532211019293144 GO:0005008 hepatocyte growth factor receptor activity 1/190 49/18639 0.0204081632653061 2.00204081632653 0.395107478023248 0.532211019293144 GO:0005009 insulin receptor activity 1/190 49/18639 0.0204081632653061 2.00204081632653 0.395107478023248 0.532211019293144 GO:0005011 macrophage colony-stimulating factor receptor activity 1/190 49/18639 0.0204081632653061 2.00204081632653 0.395107478023248 0.532211019293144 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/190 49/18639 0.0204081632653061 2.00204081632653 0.395107478023248 0.532211019293144 GO:0005020 stem cell factor receptor activity 1/190 49/18639 0.0204081632653061 2.00204081632653 0.395107478023248 0.532211019293144 GO:0008288 boss receptor activity 1/190 49/18639 0.0204081632653061 2.00204081632653 0.395107478023248 0.532211019293144 GO:0035254 glutamate receptor binding 1/190 49/18639 0.0204081632653061 2.00204081632653 0.395107478023248 0.532211019293144 GO:0036332 placental growth factor receptor activity 1/190 49/18639 0.0204081632653061 2.00204081632653 0.395107478023248 0.532211019293144 GO:0038062 protein tyrosine kinase collagen receptor activity 1/190 49/18639 0.0204081632653061 2.00204081632653 0.395107478023248 0.532211019293144 GO:0060175 brain-derived neurotrophic factor receptor activity 1/190 49/18639 0.0204081632653061 2.00204081632653 0.395107478023248 0.532211019293144 GO:0005006 epidermal growth factor receptor activity 1/190 50/18639 0.02 1.962 0.401289811491542 0.533802957965384 GO:0005007 fibroblast growth factor receptor activity 1/190 50/18639 0.02 1.962 0.401289811491542 0.533802957965384 GO:0005017 platelet-derived growth factor receptor activity 1/190 50/18639 0.02 1.962 0.401289811491542 0.533802957965384 GO:0005019 platelet-derived growth factor beta-receptor activity 1/190 50/18639 0.02 1.962 0.401289811491542 0.533802957965384 GO:0005010 insulin-like growth factor receptor activity 1/190 51/18639 0.0196078431372549 1.92352941176471 0.407409287300709 0.536925202708033 GO:0005021 vascular endothelial growth factor receptor activity 1/190 51/18639 0.0196078431372549 1.92352941176471 0.407409287300709 0.536925202708033 GO:0005030 neurotrophin receptor activity 1/190 51/18639 0.0196078431372549 1.92352941176471 0.407409287300709 0.536925202708033 GO:0005080 protein kinase C binding 1/190 52/18639 0.0192307692307692 1.88653846153846 0.413466541196387 0.537868950388894 GO:0030159 signaling receptor complex adaptor activity 1/190 52/18639 0.0192307692307692 1.88653846153846 0.413466541196387 0.537868950388894 GO:0030295 protein kinase activator activity 2/190 139/18639 0.0143884892086331 1.41151079136691 0.41525384452131 0.537868950388894 GO:0070851 growth factor receptor binding 2/190 139/18639 0.0143884892086331 1.41151079136691 0.41525384452131 0.537868950388894 GO:0044389 ubiquitin-like protein ligase binding 4/190 322/18639 0.0124223602484472 1.21863354037267 0.416606723217045 0.537868950388894 GO:0005003 ephrin receptor activity 1/190 53/18639 0.0188679245283019 1.85094339622642 0.419462202528107 0.537868950388894 GO:0005005 transmembrane-ephrin receptor activity 1/190 53/18639 0.0188679245283019 1.85094339622642 0.419462202528107 0.537868950388894 GO:0005246 calcium channel regulator activity 1/190 53/18639 0.0188679245283019 1.85094339622642 0.419462202528107 0.537868950388894 GO:0038064 collagen receptor activity 1/190 53/18639 0.0188679245283019 1.85094339622642 0.419462202528107 0.537868950388894 GO:0050661 NADP binding 1/190 54/18639 0.0185185185185185 1.81666666666667 0.425396894313304 0.542222310065017 GO:0051287 NAD binding 1/190 54/18639 0.0185185185185185 1.81666666666667 0.425396894313304 0.542222310065017 GO:0019209 kinase activator activity 2/190 148/18639 0.0135135135135135 1.32567567567568 0.446606570270001 0.567562516384793 GO:0008509 monoatomic anion transmembrane transporter activity 2/190 149/18639 0.0134228187919463 1.31677852348993 0.450032882001631 0.57021970508812 GO:0001786 phosphatidylserine binding 1/190 59/18639 0.0169491525423729 1.66271186440678 0.454177180336903 0.572075681427309 GO:0070888 E-box binding 1/190 59/18639 0.0169491525423729 1.66271186440678 0.454177180336903 0.572075681427309 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/190 60/18639 0.0166666666666667 1.635 0.459758791517527 0.577402952876424 GO:0038024 cargo receptor activity 1/190 65/18639 0.0153846153846154 1.50923076923077 0.486826545625162 0.609603914903062 GO:0016500 protein-hormone receptor activity 1/190 67/18639 0.0149253731343284 1.46417910447761 0.49727199176122 0.620862983865617 GO:0005548 phospholipid transporter activity 1/190 68/18639 0.0147058823529412 1.44264705882353 0.502415127749017 0.624565938540287 GO:0015103 inorganic anion transmembrane transporter activity 2/190 165/18639 0.0121212121212121 1.18909090909091 0.503163191704587 0.624565938540287 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/190 70/18639 0.0142857142857143 1.40142857142857 0.512544902110923 0.634367168699606 GO:0046982 protein heterodimerization activity 4/190 369/18639 0.010840108401084 1.06341463414634 0.520962924342908 0.642922452874051 GO:0004521 RNA endonuclease activity 1/190 73/18639 0.0136986301369863 1.34383561643836 0.527356188512648 0.648936865979541 GO:0031491 nucleosome binding 1/190 74/18639 0.0135135135135135 1.32567567567568 0.532193112146311 0.653007065765733 GO:0008017 microtubule binding 3/190 276/18639 0.0108695652173913 1.06630434782609 0.536168355648141 0.655116568356581 GO:0019003 GDP binding 1/190 75/18639 0.0133333333333333 1.308 0.536980793734903 0.655116568356581 GO:0019199 transmembrane receptor protein kinase activity 1/190 78/18639 0.0128205128205128 1.25769230769231 0.551053347967363 0.670369742399043 GO:0046332 SMAD binding 1/190 79/18639 0.0126582278481013 1.24177215189873 0.555648998195594 0.674040119970224 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/190 86/18639 0.0116279069767442 1.1406976744186 0.586534410906001 0.709490633022273 GO:0008081 phosphoric diester hydrolase activity 1/190 87/18639 0.0114942528735632 1.12758620689655 0.590768683634285 0.712593864157739 GO:0031625 ubiquitin protein ligase binding 3/190 302/18639 0.00993377483443709 0.974503311258278 0.597282173125102 0.716580462177944 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/190 89/18639 0.0112359550561798 1.10224719101124 0.599108255263527 0.716580462177944 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/190 89/18639 0.0112359550561798 1.10224719101124 0.599108255263527 0.716580462177944 GO:0140793 histone H2AXY142 phosphatase activity 1/190 90/18639 0.0111111111111111 1.09 0.603214424077539 0.719476422014271 GO:0072341 modified amino acid binding 1/190 91/18639 0.010989010989011 1.07802197802198 0.607278754199123 0.722306484799514 GO:0052689 carboxylic ester hydrolase activity 1/190 92/18639 0.0108695652173913 1.06630434782609 0.611301669699564 0.725071702671427 GO:0004725 protein tyrosine phosphatase activity 1/190 98/18639 0.0102040816326531 1.00102040816327 0.634592670279698 0.75061238285161 GO:0043130 ubiquitin binding 1/190 100/18639 0.01 0.981 0.642043564531364 0.75732762998589 GO:0004620 phospholipase activity 1/190 109/18639 0.00917431192660551 0.9 0.67374565407742 0.792532766642034 GO:1902936 phosphatidylinositol bisphosphate binding 1/190 111/18639 0.00900900900900901 0.883783783783784 0.680402122316879 0.798164028102493 GO:0043022 ribosome binding 1/190 112/18639 0.00892857142857143 0.875892857142857 0.683679518515055 0.79981138193405 GO:0001221 transcription coregulator binding 1/190 115/18639 0.00869565217391304 0.85304347826087 0.693312458058355 0.802288399975386 GO:0017124 SH3 domain binding 1/190 115/18639 0.00869565217391304 0.85304347826087 0.693312458058355 0.802288399975386 GO:0035401 histone H3Y41 kinase activity 1/190 115/18639 0.00869565217391304 0.85304347826087 0.693312458058355 0.802288399975386 GO:0140801 histone H2AXY142 kinase activity 1/190 115/18639 0.00869565217391304 0.85304347826087 0.693312458058355 0.802288399975386 GO:0015294 solute:monoatomic cation symporter activity 1/190 116/18639 0.00862068965517241 0.845689655172414 0.696458141116491 0.803750341234437 GO:0045182 translation regulator activity 3/190 356/18639 0.00842696629213483 0.826685393258427 0.706540941741744 0.813188631061252 GO:0032182 ubiquitin-like protein binding 1/190 120/18639 0.00833333333333333 0.8175 0.708723144079682 0.813507479897915 GO:0004540 RNA nuclease activity 1/190 121/18639 0.00826446280991736 0.810743801652893 0.711711566922431 0.814747557844177 GO:0042578 phosphoric ester hydrolase activity 3/190 363/18639 0.00826446280991736 0.810743801652893 0.718911994446453 0.820789897402769 GO:0140104 molecular carrier activity 2/190 249/18639 0.00803212851405622 0.787951807228916 0.724102060351547 0.824510879386961 GO:0004519 endonuclease activity 1/190 127/18639 0.0078740157480315 0.77244094488189 0.729012318923491 0.825698302865598 GO:0042826 histone deacetylase binding 1/190 127/18639 0.0078740157480315 0.77244094488189 0.729012318923491 0.825698302865598 GO:0016298 lipase activity 1/190 130/18639 0.00769230769230769 0.754615384615385 0.73727135241995 0.832843564770684 GO:0044325 transmembrane transporter binding 1/190 136/18639 0.00735294117647059 0.721323529411765 0.753045682985913 0.846185543776277 GO:0140789 histone phosphatase activity 1/190 136/18639 0.00735294117647059 0.721323529411765 0.753045682985913 0.846185543776277 GO:0015631 tubulin binding 3/190 385/18639 0.00779220779220779 0.764415584415584 0.755175363536332 0.846351391679827 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/190 268/18639 0.00746268656716418 0.732089552238806 0.760866857213706 0.850497769712703 GO:0004713 protein tyrosine kinase activity 1/190 140/18639 0.00714285714285714 0.700714285714286 0.763034813105052 0.850694165002238 GO:0016791 phosphatase activity 2/190 273/18639 0.00732600732600733 0.718681318681319 0.769813145809226 0.856016180365988 GO:0008194 UDP-glycosyltransferase activity 1/190 145/18639 0.00689655172413793 0.676551724137931 0.774957796149349 0.858930035072745 GO:0015293 symporter activity 1/190 146/18639 0.00684931506849315 0.671917808219178 0.777269790241034 0.858930035072745 GO:0001217 DNA-binding transcription repressor activity 2/190 278/18639 0.00719424460431655 0.705755395683453 0.778468205089349 0.858930035072745 GO:0019842 vitamin binding 1/190 150/18639 0.00666666666666667 0.654 0.786283868996757 0.865317556859833 GO:0035091 phosphatidylinositol binding 2/190 284/18639 0.00704225352112676 0.690845070422535 0.788479143276138 0.865502812799257 GO:0003774 cytoskeletal motor activity 1/190 153/18639 0.0065359477124183 0.641176470588235 0.792805427071969 0.868020300922387 GO:0016874 ligase activity 1/190 167/18639 0.00598802395209581 0.587425149700599 0.820716218446093 0.896280883060055 GO:0004721 phosphoprotein phosphatase activity 1/190 175/18639 0.00571428571428571 0.560571428571429 0.834951174535468 0.908808311502554 GO:0043021 ribonucleoprotein complex binding 1/190 177/18639 0.00564971751412429 0.554237288135593 0.83833059061506 0.908808311502554 GO:0005216 monoatomic ion channel activity 3/190 448/18639 0.00669642857142857 0.656919642857143 0.838572540355987 0.908808311502554 GO:1901981 phosphatidylinositol phosphate binding 1/190 185/18639 0.00540540540540541 0.53027027027027 0.851173687840552 0.917364388784802 GO:0003924 GTPase activity 2/190 331/18639 0.00604229607250755 0.592749244712991 0.854031432066459 0.917364388784802 GO:0046943 carboxylic acid transmembrane transporter activity 1/190 188/18639 0.00531914893617021 0.521808510638298 0.855723654761601 0.917364388784802 GO:0140597 protein carrier chaperone 1/190 188/18639 0.00531914893617021 0.521808510638298 0.855723654761601 0.917364388784802 GO:0005342 organic acid transmembrane transporter activity 1/190 189/18639 0.00529100529100529 0.519047619047619 0.857209346897274 0.917364388784802 GO:0016758 hexosyltransferase activity 1/190 197/18639 0.0050761421319797 0.497969543147208 0.868559821039814 0.927187608960002 GO:0016829 lyase activity 1/190 200/18639 0.005 0.4905 0.872580841239596 0.92816929253836 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 2/190 349/18639 0.00573065902578797 0.562177650429799 0.87382682810403 0.92816929253836 GO:0003714 transcription corepressor activity 1/190 204/18639 0.00490196078431373 0.480882352941176 0.87775247101037 0.930025571020913 GO:0004518 nuclease activity 1/190 209/18639 0.00478468899521531 0.469377990430622 0.883924312528332 0.93424673626138 GO:0005525 GTP binding 2/190 378/18639 0.00529100529100529 0.519047619047619 0.900604830660307 0.949526574548027 GO:0000287 magnesium ion binding 1/190 230/18639 0.00434782608695652 0.426521739130435 0.906636063867219 0.953531032687937 GO:0019001 guanyl nucleotide binding 2/190 400/18639 0.005 0.4905 0.917293034663647 0.960010112258277 GO:0032561 guanyl ribonucleotide binding 2/190 400/18639 0.005 0.4905 0.917293034663647 0.960010112258277 GO:0042393 histone binding 1/190 247/18639 0.00404858299595142 0.397165991902834 0.921738274111956 0.96230377272813 GO:0003713 transcription coactivator activity 1/190 256/18639 0.00390625 0.383203125 0.928722589934005 0.967230599760537 GO:0016757 glycosyltransferase activity 1/190 267/18639 0.00374531835205993 0.367415730337079 0.936422186054386 0.970842830483387 GO:0008514 organic anion transmembrane transporter activity 1/190 269/18639 0.00371747211895911 0.364684014869888 0.937730442805554 0.970842830483387 GO:0005096 GTPase activator activity 1/190 271/18639 0.003690036900369 0.361992619926199 0.939011918008522 0.970842830483387 GO:0015291 secondary active transmembrane transporter activity 1/190 287/18639 0.00348432055749129 0.341811846689896 0.948362767675861 0.978142274873412 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 2/190 484/18639 0.00413223140495868 0.405371900826446 0.959782853926494 0.984223910047178 GO:0140297 DNA-binding transcription factor binding 2/190 488/18639 0.00409836065573771 0.402049180327869 0.961166469122793 0.984223910047178 GO:0001216 DNA-binding transcription activator activity 2/190 491/18639 0.00407331975560081 0.39959266802444 0.962174241274765 0.984223910047178 GO:0003712 transcription coregulator activity 2/190 495/18639 0.00404040404040404 0.396363636363636 0.963479143793256 0.984223910047178 GO:0005261 monoatomic cation channel activity 1/190 341/18639 0.00293255131964809 0.287683284457478 0.970586776801939 0.987442947578295 GO:0141003 histone H2AX kinase activity 1/190 354/18639 0.00282485875706215 0.277118644067797 0.974320154998135 0.987442947578295 GO:0140996 histone H3 kinase activity 1/190 357/18639 0.00280112044817927 0.274789915966387 0.975112428647453 0.987442947578295 GO:0035173 histone kinase activity 1/190 360/18639 0.00277777777777778 0.2725 0.975880383789322 0.987442947578295 GO:0140098 catalytic activity, acting on RNA 1/190 387/18639 0.00258397932816537 0.253488372093023 0.981813039945934 0.991097324011616 GO:0016887 ATP hydrolysis activity 1/190 417/18639 0.00239808153477218 0.235251798561151 0.986716502163133 0.99369798684825 GO:0046873 metal ion transmembrane transporter activity 1/190 450/18639 0.00222222222222222 0.218 0.990603654972089 0.993829160755564 GO:0030695 GTPase regulator activity 1/190 489/18639 0.00204498977505112 0.200613496932515 0.993763879048635 0.993829160755564 GO:0060589 nucleoside-triphosphatase regulator activity 1/190 490/18639 0.00204081632653061 0.200204081632653 0.993829160755564 0.993829160755564