ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 38/177 175/18639 0.217142857142857 22.8662469733656 3.14697664740503e-41 1.17067531283467e-38 GO:0005201 extracellular matrix structural constituent 17/177 168/18639 0.101190476190476 10.6558716707022 4.54112954048894e-13 8.44650094530943e-11 GO:0019838 growth factor binding 14/177 136/18639 0.102941176470588 10.8402293120638 4.48940013583058e-11 5.56685616842992e-09 GO:0005520 insulin-like growth factor binding 7/177 19/18639 0.368421052631579 38.7966101694915 2.82974366231679e-10 2.63166160595461e-08 GO:0031994 insulin-like growth factor I binding 6/177 13/18639 0.461538461538462 48.6023468057366 1.09390390329863e-09 8.13864504054183e-08 GO:0008201 heparin binding 13/177 172/18639 0.0755813953488372 7.9591052424123 1.0291608601348e-08 4.5371404313033e-07 GO:0019843 rRNA binding 9/177 65/18639 0.138461538461538 14.580704041721 1.03686391483516e-08 4.5371404313033e-07 GO:0001968 fibronectin binding 7/177 30/18639 0.233333333333333 24.571186440678 1.04692611245882e-08 4.5371404313033e-07 GO:0005539 glycosaminoglycan binding 15/177 242/18639 0.0619834710743802 6.52717467432413 1.09769526563789e-08 4.5371404313033e-07 GO:0050840 extracellular matrix binding 9/177 67/18639 0.134328358208955 14.1454591449532 1.36450279875648e-08 5.07595041137411e-07 GO:0005518 collagen binding 9/177 72/18639 0.125 13.1631355932203 2.60795737978135e-08 8.81963768435147e-07 GO:0004857 enzyme inhibitor activity 17/177 416/18639 0.0408653846153846 4.30333279009126 4.88031333993246e-07 1.51289713537906e-05 GO:0061134 peptidase regulator activity 12/177 226/18639 0.0530973451327434 5.59142042897855 1.75287917030417e-06 5.01593116425502e-05 GO:1901681 sulfur compound binding 13/177 275/18639 0.0472727272727273 4.97805855161787 2.35149629811265e-06 6.24826159212789e-05 GO:0008191 metalloendopeptidase inhibitor activity 4/177 14/18639 0.285714285714286 30.0871670702179 7.30501390546011e-06 0.000181164344855411 GO:0004896 cytokine receptor activity 7/177 96/18639 0.0729166666666667 7.67849576271186 3.62060273029314e-05 0.000841790134793154 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/177 22/18639 0.181818181818182 19.1463790446841 5.03032909916826e-05 0.0011007543675827 GO:1990948 ubiquitin ligase inhibitor activity 3/177 11/18639 0.272727272727273 28.7195685670262 0.000131350511152258 0.00271457723047999 GO:0005178 integrin binding 8/177 161/18639 0.0496894409937888 5.23255079482051 0.000154281037657969 0.00302066031625076 GO:0016504 peptidase activator activity 5/177 57/18639 0.087719298245614 9.23728813559322 0.000204919591121963 0.00381150439486851 GO:0055105 ubiquitin-protein transferase inhibitor activity 3/177 15/18639 0.2 21.0610169491525 0.000352210139290928 0.00623915103886786 GO:0019955 cytokine binding 7/177 144/18639 0.0486111111111111 5.11899717514124 0.000456017244134451 0.00771083703718253 GO:0140375 immune receptor activity 7/177 156/18639 0.0448717948717949 4.72522816166884 0.000734737577499609 0.0118835816882545 GO:0030547 signaling receptor inhibitor activity 4/177 44/18639 0.0909090909090909 9.57318952234207 0.00079334376859166 0.0122968284131707 GO:0004866 endopeptidase inhibitor activity 7/177 161/18639 0.0434782608695652 4.57848194546794 0.000884621912675468 0.013163174060611 GO:0030414 peptidase inhibitor activity 7/177 169/18639 0.0414201183431953 4.3617490723097 0.00117359470685632 0.0167914319596366 GO:0045296 cadherin binding 10/177 334/18639 0.029940119760479 3.15284684867553 0.00137092045713762 0.0188882374094517 GO:0019207 kinase regulator activity 9/177 287/18639 0.0313588850174216 3.30225004429221 0.00172823247573178 0.0229608028918651 GO:0050750 low-density lipoprotein particle receptor binding 3/177 26/18639 0.115384615384615 12.1505867014342 0.00186398244588865 0.0236934413062273 GO:0061135 endopeptidase regulator activity 7/177 184/18639 0.0380434782608696 4.00617170228445 0.00191076139566349 0.0236934413062273 GO:0043236 laminin binding 3/177 29/18639 0.103448275862069 10.8936294564582 0.00256553365394336 0.0307864038473203 GO:0019887 protein kinase regulator activity 8/177 255/18639 0.0313725490196078 3.3036889332004 0.00308165983683671 0.0350861079966262 GO:0070325 lipoprotein particle receptor binding 3/177 31/18639 0.0967741935483871 10.1908146528157 0.00311247732228136 0.0350861079966262 GO:0019888 protein phosphatase regulator activity 5/177 107/18639 0.0467289719626168 4.92079835260573 0.00355653879215454 0.0389127185494555 GO:0004222 metalloendopeptidase activity 5/177 110/18639 0.0454545454545455 4.78659476117103 0.00400271371747997 0.0425431286543586 GO:0097110 scaffold protein binding 4/177 70/18639 0.0571428571428571 6.01743341404358 0.00442706032650685 0.0451025666515616 GO:0003953 NAD+ nucleosidase activity 2/177 11/18639 0.181818181818182 19.1463790446841 0.00466182225816322 0.0451025666515616 GO:0050786 RAGE receptor binding 2/177 11/18639 0.181818181818182 19.1463790446841 0.00466182225816322 0.0451025666515616 GO:0055106 ubiquitin-protein transferase regulator activity 3/177 36/18639 0.0833333333333333 8.77542372881356 0.00477548166253161 0.0451025666515616 GO:0005126 cytokine receptor binding 8/177 275/18639 0.0290909090909091 3.06342064714946 0.00484973834963028 0.0451025666515616 GO:0043394 proteoglycan binding 3/177 37/18639 0.0810810810810811 8.5382501145213 0.00516098555940939 0.0460329660686138 GO:0019208 phosphatase regulator activity 5/177 117/18639 0.0427350427350427 4.50021729682747 0.00519727036258543 0.0460329660686138 GO:0097371 MDM2/MDM4 family protein binding 2/177 12/18639 0.166666666666667 17.5508474576271 0.00555940434048652 0.0480953119688601 GO:0048306 calcium-dependent protein binding 4/177 80/18639 0.05 5.26525423728814 0.00709856231944581 0.0600151177916782 GO:0008307 structural constituent of muscle 3/177 42/18639 0.0714285714285714 7.52179176755448 0.00736610212043434 0.0608931108622572 GO:0001540 amyloid-beta binding 4/177 83/18639 0.0481927710843374 5.07494384316929 0.00806936952567617 0.0633188104959812 GO:0008237 metallopeptidase activity 6/177 184/18639 0.0326086956521739 3.43386145910096 0.00833959635891931 0.0633188104959812 GO:0001223 transcription coactivator binding 3/177 44/18639 0.0681818181818182 7.17989214175655 0.00838143789634413 0.0633188104959812 GO:0004860 protein kinase inhibitor activity 4/177 84/18639 0.0476190476190476 5.01452784503632 0.00841135228407444 0.0633188104959812 GO:0004129 cytochrome-c oxidase activity 2/177 15/18639 0.133333333333333 14.0406779661017 0.00868080466477161 0.0633188104959812 GO:0005523 tropomyosin binding 2/177 15/18639 0.133333333333333 14.0406779661017 0.00868080466477161 0.0633188104959812 GO:0033218 amide binding 7/177 247/18639 0.0283400809716599 2.98435462842243 0.00943460559866696 0.0643457142712834 GO:0002020 protease binding 5/177 136/18639 0.0367647058823529 3.87151046859422 0.00967583601722188 0.0643457142712834 GO:0042277 peptide binding 7/177 249/18639 0.0281124497991968 2.96038390851542 0.00983471543552807 0.0643457142712834 GO:0008142 oxysterol binding 2/177 16/18639 0.125 13.1631355932203 0.00985942396092245 0.0643457142712834 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/177 16/18639 0.125 13.1631355932203 0.00985942396092245 0.0643457142712834 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/177 16/18639 0.125 13.1631355932203 0.00985942396092245 0.0643457142712834 GO:0019210 kinase inhibitor activity 4/177 90/18639 0.0444444444444444 4.68022598870057 0.0106631867739847 0.0683914737917642 GO:0070492 oligosaccharide binding 2/177 17/18639 0.117647058823529 12.3888334995015 0.011104804047934 0.0700167306073129 GO:0098641 cadherin binding involved in cell-cell adhesion 2/177 18/18639 0.111111111111111 11.7005649717514 0.0124155854822146 0.0769766299897302 GO:0004867 serine-type endopeptidase inhibitor activity 4/177 95/18639 0.0421052631578947 4.43389830508475 0.0128116677709695 0.0781301706688629 GO:0004864 protein phosphatase inhibitor activity 3/177 53/18639 0.0566037735849057 5.96066517428846 0.0139342450271759 0.0822783992080865 GO:0017046 peptide hormone binding 3/177 53/18639 0.0566037735849057 5.96066517428846 0.0139342450271759 0.0822783992080865 GO:0019212 phosphatase inhibitor activity 3/177 56/18639 0.0535714285714286 5.64134382566586 0.0161522452506009 0.0938849255191179 GO:0072542 protein phosphatase activator activity 2/177 21/18639 0.0952380952380952 10.0290556900726 0.0167270351189687 0.0957301086808669 GO:0005496 steroid binding 4/177 108/18639 0.037037037037037 3.90018832391714 0.0196294840482149 0.10888815688114 GO:0005212 structural constituent of eye lens 2/177 23/18639 0.0869565217391304 9.15696389093589 0.0199042867417138 0.10888815688114 GO:0017134 fibroblast growth factor binding 2/177 23/18639 0.0869565217391304 9.15696389093589 0.0199042867417138 0.10888815688114 GO:0048027 mRNA 5'-UTR binding 2/177 24/18639 0.0833333333333333 8.77542372881356 0.0215800053856656 0.116344376861849 GO:0019211 phosphatase activator activity 2/177 25/18639 0.08 8.42440677966102 0.0233121429630456 0.123887388317899 GO:0001221 transcription coregulator binding 4/177 115/18639 0.0347826086956522 3.66278555637435 0.0240751501450664 0.126140223295277 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 3/177 68/18639 0.0441176470588235 4.64581256231306 0.0269007268170928 0.137083155835048 GO:0032934 sterol binding 3/177 68/18639 0.0441176470588235 4.64581256231306 0.0269007268170928 0.137083155835048 GO:0051082 unfolded protein binding 4/177 121/18639 0.0330578512396694 3.48115982630621 0.0283338140671891 0.142434849094518 GO:0048019 receptor antagonist activity 2/177 30/18639 0.0666666666666667 7.02033898305085 0.0327773852674647 0.162575830926625 GO:0005179 hormone activity 4/177 132/18639 0.0303030303030303 3.19106317411402 0.0372388585015734 0.182274412665596 GO:0004175 endopeptidase activity 8/177 405/18639 0.0197530864197531 2.08010043942247 0.0398928541370022 0.19272911349305 GO:0030295 protein kinase activator activity 4/177 139/18639 0.0287769784172662 3.0303621509572 0.0436535789499677 0.208193991915231 GO:0005501 retinoid binding 2/177 38/18639 0.0526315789473684 5.54237288135593 0.0504370443015655 0.23453225600228 GO:0019840 isoprenoid binding 2/177 38/18639 0.0526315789473684 5.54237288135593 0.0504370443015655 0.23453225600228 GO:0019209 kinase activator activity 4/177 148/18639 0.027027027027027 2.8460833715071 0.0527571914037503 0.236823968671968 GO:0000217 DNA secondary structure binding 2/177 39/18639 0.0512820512820513 5.40026075619296 0.0528397564510035 0.236823968671968 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/177 39/18639 0.0512820512820513 5.40026075619296 0.0528397564510035 0.236823968671968 GO:0043178 alcohol binding 3/177 92/18639 0.0326086956521739 3.43386145910096 0.0572854838515361 0.253692857056803 GO:0042056 chemoattractant activity 2/177 42/18639 0.0476190476190476 5.01452784503632 0.0602842079906578 0.260955676037267 GO:0042562 hormone binding 3/177 94/18639 0.0319148936170213 3.36080057699243 0.0603284627397982 0.260955676037267 GO:0008200 ion channel inhibitor activity 2/177 43/18639 0.0465116279069767 4.89791091840757 0.0628412879979007 0.268700679715161 GO:0016248 channel inhibitor activity 2/177 44/18639 0.0454545454545455 4.78659476117103 0.0654346141932129 0.276609959998582 GO:0099106 ion channel regulator activity 4/177 160/18639 0.025 2.63262711864407 0.0663775413005152 0.277443206334738 GO:0042605 peptide antigen binding 2/177 45/18639 0.0444444444444444 4.68022598870057 0.068063276580297 0.278230268328776 GO:0141110 transporter inhibitor activity 2/177 45/18639 0.0444444444444444 4.68022598870057 0.068063276580297 0.278230268328776 GO:0008083 growth factor activity 4/177 162/18639 0.0246913580246914 2.60012554927809 0.0688096362533533 0.278230268328776 GO:0030291 protein serine/threonine kinase inhibitor activity 2/177 46/18639 0.0434782608695652 4.57848194546794 0.0707263790019562 0.282905516007825 GO:0005125 cytokine activity 5/177 234/18639 0.0213675213675214 2.25010864841373 0.0727370425240772 0.287509163092502 GO:0005504 fatty acid binding 2/177 47/18639 0.0425531914893617 4.4810674359899 0.0734230389617948 0.287509163092502 GO:0016247 channel regulator activity 4/177 168/18639 0.0238095238095238 2.50726392251816 0.0763781738333804 0.295965423604349 GO:0141108 transporter regulator activity 4/177 170/18639 0.0235294117647059 2.4777666999003 0.0789906676031267 0.302933281941888 GO:0004252 serine-type endopeptidase activity 4/177 176/18639 0.0227272727272727 2.39329738058552 0.0870919486677102 0.313534964634796 GO:0005080 protein kinase C binding 2/177 52/18639 0.0384615384615385 4.05019556714472 0.0873797486899261 0.313534964634796 GO:0005200 structural constituent of cytoskeleton 3/177 112/18639 0.0267857142857143 2.82067191283293 0.090927186397753 0.313534964634796 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/177 10/18639 0.1 10.5305084745763 0.0910262800552634 0.313534964634796 GO:0004955 prostaglandin receptor activity 1/177 10/18639 0.1 10.5305084745763 0.0910262800552634 0.313534964634796 GO:0005131 growth hormone receptor binding 1/177 10/18639 0.1 10.5305084745763 0.0910262800552634 0.313534964634796 GO:0005381 iron ion transmembrane transporter activity 1/177 10/18639 0.1 10.5305084745763 0.0910262800552634 0.313534964634796 GO:0031720 haptoglobin binding 1/177 10/18639 0.1 10.5305084745763 0.0910262800552634 0.313534964634796 GO:0032356 oxidized DNA binding 1/177 10/18639 0.1 10.5305084745763 0.0910262800552634 0.313534964634796 GO:0035374 chondroitin sulfate binding 1/177 10/18639 0.1 10.5305084745763 0.0910262800552634 0.313534964634796 GO:0070513 death domain binding 1/177 10/18639 0.1 10.5305084745763 0.0910262800552634 0.313534964634796 GO:0015485 cholesterol binding 2/177 54/18639 0.037037037037037 3.90018832391714 0.0931679283751372 0.316451927941355 GO:0098632 cell-cell adhesion mediator activity 2/177 55/18639 0.0363636363636364 3.82927580893683 0.096102860875081 0.316451927941355 GO:0140313 molecular sequestering activity 2/177 55/18639 0.0363636363636364 3.82927580893683 0.096102860875081 0.316451927941355 GO:0009055 electron transfer activity 3/177 116/18639 0.0258620689655172 2.72340736411455 0.0984585889224697 0.316451927941355 GO:0004954 prostanoid receptor activity 1/177 11/18639 0.0909090909090909 9.57318952234207 0.0996627258349735 0.316451927941355 GO:0034713 type I transforming growth factor beta receptor binding 1/177 11/18639 0.0909090909090909 9.57318952234207 0.0996627258349735 0.316451927941355 GO:0048185 activin binding 1/177 11/18639 0.0909090909090909 9.57318952234207 0.0996627258349735 0.316451927941355 GO:0050998 nitric-oxide synthase binding 1/177 11/18639 0.0909090909090909 9.57318952234207 0.0996627258349735 0.316451927941355 GO:0097493 structural molecule activity conferring elasticity 1/177 11/18639 0.0909090909090909 9.57318952234207 0.0996627258349735 0.316451927941355 GO:1990782 protein tyrosine kinase binding 3/177 117/18639 0.0256410256410256 2.70013037809648 0.100379912626559 0.316451927941355 GO:0022853 active monoatomic ion transmembrane transporter activity 3/177 118/18639 0.0254237288135593 2.67724791726515 0.102316287389707 0.31984587318463 GO:0019902 phosphatase binding 4/177 190/18639 0.0210526315789474 2.21694915254237 0.107479187650923 0.329974895463981 GO:0070888 E-box binding 2/177 59/18639 0.0338983050847458 3.56966388968687 0.108097111582288 0.329974895463981 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/177 12/18639 0.0833333333333333 8.77542372881356 0.108217573243564 0.329974895463981 GO:0008236 serine-type peptidase activity 4/177 194/18639 0.0206185567010309 2.17123886073738 0.113668742960462 0.33913493022556 GO:0015026 coreceptor activity 2/177 61/18639 0.0327868852459016 3.45262572936927 0.114236662977718 0.33913493022556 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/177 13/18639 0.0769230769230769 8.10039113428944 0.116691588894816 0.33913493022556 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/177 13/18639 0.0769230769230769 8.10039113428944 0.116691588894816 0.33913493022556 GO:0035673 oligopeptide transmembrane transporter activity 1/177 13/18639 0.0769230769230769 8.10039113428944 0.116691588894816 0.33913493022556 GO:0039706 co-receptor binding 1/177 13/18639 0.0769230769230769 8.10039113428944 0.116691588894816 0.33913493022556 GO:0017171 serine hydrolase activity 4/177 198/18639 0.0202020202020202 2.12737544940935 0.120012745427226 0.3421457205415 GO:0005507 copper ion binding 2/177 63/18639 0.0317460317460317 3.34301856335755 0.120463603038903 0.3421457205415 GO:0004536 DNA nuclease activity 2/177 64/18639 0.03125 3.29078389830508 0.123608134291845 0.3421457205415 GO:0005161 platelet-derived growth factor receptor binding 1/177 14/18639 0.0714285714285714 7.52179176755448 0.125085532240979 0.3421457205415 GO:0005344 oxygen carrier activity 1/177 14/18639 0.0714285714285714 7.52179176755448 0.125085532240979 0.3421457205415 GO:0008494 translation activator activity 1/177 14/18639 0.0714285714285714 7.52179176755448 0.125085532240979 0.3421457205415 GO:0032036 myosin heavy chain binding 1/177 14/18639 0.0714285714285714 7.52179176755448 0.125085532240979 0.3421457205415 GO:0044548 S100 protein binding 1/177 14/18639 0.0714285714285714 7.52179176755448 0.125085532240979 0.3421457205415 GO:0030246 carbohydrate binding 5/177 280/18639 0.0178571428571429 1.88044794188862 0.128611064078539 0.347026978306376 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/177 15/18639 0.0666666666666667 7.02033898305085 0.133400155639279 0.347026978306376 GO:0004953 icosanoid receptor activity 1/177 15/18639 0.0666666666666667 7.02033898305085 0.133400155639279 0.347026978306376 GO:0031386 protein tag activity 1/177 15/18639 0.0666666666666667 7.02033898305085 0.133400155639279 0.347026978306376 GO:0051371 muscle alpha-actinin binding 1/177 15/18639 0.0666666666666667 7.02033898305085 0.133400155639279 0.347026978306376 GO:0120283 protein serine/threonine kinase binding 1/177 15/18639 0.0666666666666667 7.02033898305085 0.133400155639279 0.347026978306376 GO:0141047 molecular tag activity 1/177 15/18639 0.0666666666666667 7.02033898305085 0.133400155639279 0.347026978306376 GO:0051087 protein-folding chaperone binding 3/177 134/18639 0.0223880597014925 2.35757652415887 0.135203903458639 0.349276750601484 GO:0008296 3'-5'-DNA exonuclease activity 1/177 16/18639 0.0625 6.58156779661017 0.141636204417836 0.356004513806994 GO:0015562 efflux transmembrane transporter activity 1/177 16/18639 0.0625 6.58156779661017 0.141636204417836 0.356004513806994 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/177 16/18639 0.0625 6.58156779661017 0.141636204417836 0.356004513806994 GO:0019841 retinol binding 1/177 16/18639 0.0625 6.58156779661017 0.141636204417836 0.356004513806994 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/177 17/18639 0.0588235294117647 6.19441674975075 0.149794416940955 0.364206033346636 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/177 17/18639 0.0588235294117647 6.19441674975075 0.149794416940955 0.364206033346636 GO:0048038 quinone binding 1/177 17/18639 0.0588235294117647 6.19441674975075 0.149794416940955 0.364206033346636 GO:0051787 misfolded protein binding 1/177 17/18639 0.0588235294117647 6.19441674975075 0.149794416940955 0.364206033346636 GO:0070403 NAD+ binding 1/177 17/18639 0.0588235294117647 6.19441674975075 0.149794416940955 0.364206033346636 GO:0019903 protein phosphatase binding 3/177 144/18639 0.0208333333333333 2.19385593220339 0.157374073406226 0.378901259217174 GO:0000400 four-way junction DNA binding 1/177 18/18639 0.0555555555555556 5.85028248587571 0.157875524673822 0.378901259217174 GO:0044183 protein folding chaperone 2/177 75/18639 0.0266666666666667 2.80813559322034 0.159367111855172 0.380029266731564 GO:0017022 myosin binding 2/177 76/18639 0.0263157894736842 2.77118644067797 0.162708523284857 0.383085890265613 GO:0098631 cell adhesion mediator activity 2/177 76/18639 0.0263157894736842 2.77118644067797 0.162708523284857 0.383085890265613 GO:0008301 DNA binding, bending 1/177 19/18639 0.0526315789473684 5.54237288135593 0.165880252246602 0.38567158647335 GO:0016918 retinal binding 1/177 19/18639 0.0526315789473684 5.54237288135593 0.165880252246602 0.38567158647335 GO:0033293 monocarboxylic acid binding 2/177 79/18639 0.0253164556962025 2.66595151255095 0.172806407916614 0.394250403150455 GO:0046332 SMAD binding 2/177 79/18639 0.0253164556962025 2.66595151255095 0.172806407916614 0.394250403150455 GO:0016505 peptidase activator activity involved in apoptotic process 1/177 20/18639 0.05 5.26525423728814 0.173809317517942 0.394250403150455 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/177 20/18639 0.05 5.26525423728814 0.173809317517942 0.394250403150455 GO:0030971 receptor tyrosine kinase binding 2/177 81/18639 0.0246913580246914 2.60012554927809 0.179594448869671 0.404903848360713 GO:0036122 BMP binding 1/177 21/18639 0.0476190476190476 5.01452784503632 0.181663431637891 0.407101184152382 GO:0005254 chloride channel activity 2/177 83/18639 0.0240963855421687 2.53747192158464 0.186422640245399 0.415264803420888 GO:0005243 gap junction channel activity 1/177 22/18639 0.0454545454545455 4.78659476117103 0.189443299110234 0.419481590886948 GO:0005158 insulin receptor binding 1/177 23/18639 0.0434782608695652 4.57848194546794 0.197149617854258 0.431409752010494 GO:0031681 G-protein beta-subunit binding 1/177 23/18639 0.0434782608695652 4.57848194546794 0.197149617854258 0.431409752010494 GO:0005540 hyaluronic acid binding 1/177 24/18639 0.0416666666666667 4.38771186440678 0.204783079265936 0.44290293887749 GO:0050431 transforming growth factor beta binding 1/177 24/18639 0.0416666666666667 4.38771186440678 0.204783079265936 0.44290293887749 GO:0015399 primary active transmembrane transporter activity 3/177 166/18639 0.0180722891566265 1.90310394118848 0.20952879237929 0.450547461069919 GO:0001848 complement binding 1/177 25/18639 0.04 4.21220338983051 0.212344368278557 0.451383457140703 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/177 25/18639 0.04 4.21220338983051 0.212344368278557 0.451383457140703 GO:0004529 DNA exonuclease activity 1/177 26/18639 0.0384615384615385 4.05019556714472 0.219834163422786 0.451813860736334 GO:0005160 transforming growth factor beta receptor binding 1/177 26/18639 0.0384615384615385 4.05019556714472 0.219834163422786 0.451813860736334 GO:0008143 poly(A) binding 1/177 26/18639 0.0384615384615385 4.05019556714472 0.219834163422786 0.451813860736334 GO:0019865 immunoglobulin binding 1/177 26/18639 0.0384615384615385 4.05019556714472 0.219834163422786 0.451813860736334 GO:0043548 phosphatidylinositol 3-kinase binding 1/177 26/18639 0.0384615384615385 4.05019556714472 0.219834163422786 0.451813860736334 GO:0070412 R-SMAD binding 1/177 26/18639 0.0384615384615385 4.05019556714472 0.219834163422786 0.451813860736334 GO:0008266 poly(U) RNA binding 1/177 27/18639 0.037037037037037 3.90018832391714 0.227253136886181 0.461957196293221 GO:0023026 MHC class II protein complex binding 1/177 27/18639 0.037037037037037 3.90018832391714 0.227253136886181 0.461957196293221 GO:0003823 antigen binding 3/177 174/18639 0.0172413793103448 1.8156049094097 0.229372049686822 0.463730448279879 GO:0051393 alpha-actinin binding 1/177 28/18639 0.0357142857142857 3.76089588377724 0.234601954572144 0.471740146491015 GO:0004181 metallocarboxypeptidase activity 1/177 29/18639 0.0344827586206897 3.6312098188194 0.241881276158342 0.478616142185656 GO:0004629 phospholipase C activity 1/177 29/18639 0.0344827586206897 3.6312098188194 0.241881276158342 0.478616142185656 GO:0051861 glycolipid binding 1/177 29/18639 0.0344827586206897 3.6312098188194 0.241881276158342 0.478616142185656 GO:0003779 actin binding 6/177 443/18639 0.0135440180586907 1.42625396946857 0.245749223400112 0.483696884152601 GO:0001965 G-protein alpha-subunit binding 1/177 30/18639 0.0333333333333333 3.51016949152542 0.249091755154579 0.485142057159704 GO:0008187 poly-pyrimidine tract binding 1/177 30/18639 0.0333333333333333 3.51016949152542 0.249091755154579 0.485142057159704 GO:0045182 translation regulator activity 5/177 356/18639 0.0140449438202247 1.47900399923824 0.250541044387069 0.485423273499946 GO:0005253 monoatomic anion channel activity 2/177 103/18639 0.0194174757281553 2.04475892710219 0.256114560043056 0.488132815110724 GO:0005164 tumor necrosis factor receptor binding 1/177 31/18639 0.032258064516129 3.39693821760525 0.256234038960138 0.488132815110724 GO:0072349 modified amino acid transmembrane transporter activity 1/177 31/18639 0.032258064516129 3.39693821760525 0.256234038960138 0.488132815110724 GO:0015078 proton transmembrane transporter activity 3/177 185/18639 0.0162162162162162 1.70765002290426 0.25718825742393 0.488132815110724 GO:0031406 carboxylic acid binding 3/177 187/18639 0.0160427807486631 1.68938638629566 0.262297899138901 0.492215387127934 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/177 32/18639 0.03125 3.29078389830508 0.263308768920588 0.492215387127934 GO:0070717 poly-purine tract binding 1/177 32/18639 0.03125 3.29078389830508 0.263308768920588 0.492215387127934 GO:0043177 organic acid binding 3/177 189/18639 0.0158730158730159 1.67150928167877 0.267420621017214 0.495358462575739 GO:0030296 protein tyrosine kinase activator activity 1/177 33/18639 0.0303030303030303 3.19106317411402 0.270316580384072 0.495358462575739 GO:0071889 14-3-3 protein binding 1/177 33/18639 0.0303030303030303 3.19106317411402 0.270316580384072 0.495358462575739 GO:0140311 protein sequestering activity 1/177 33/18639 0.0303030303030303 3.19106317411402 0.270316580384072 0.495358462575739 GO:0015035 protein-disulfide reductase activity 1/177 34/18639 0.0294117647058824 3.09720837487537 0.277258102757071 0.49826093828807 GO:0019825 oxygen binding 1/177 34/18639 0.0294117647058824 3.09720837487537 0.277258102757071 0.49826093828807 GO:0030332 cyclin binding 1/177 34/18639 0.0294117647058824 3.09720837487537 0.277258102757071 0.49826093828807 GO:0051427 hormone receptor binding 1/177 34/18639 0.0294117647058824 3.09720837487537 0.277258102757071 0.49826093828807 GO:0000175 3'-5'-RNA exonuclease activity 1/177 35/18639 0.0285714285714286 3.00871670702179 0.284133959559651 0.50573125816359 GO:0016229 steroid dehydrogenase activity 1/177 35/18639 0.0285714285714286 3.00871670702179 0.284133959559651 0.50573125816359 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/177 36/18639 0.0277777777777778 2.92514124293785 0.290944768480203 0.512945279026709 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/177 36/18639 0.0277777777777778 2.92514124293785 0.290944768480203 0.512945279026709 GO:0022829 wide pore channel activity 1/177 37/18639 0.027027027027027 2.8460833715071 0.297691141429674 0.515074905171342 GO:0023023 MHC protein complex binding 1/177 37/18639 0.027027027027027 2.8460833715071 0.297691141429674 0.515074905171342 GO:0030280 structural constituent of skin epidermis 1/177 37/18639 0.027027027027027 2.8460833715071 0.297691141429674 0.515074905171342 GO:0042805 actinin binding 1/177 37/18639 0.027027027027027 2.8460833715071 0.297691141429674 0.515074905171342 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/177 38/18639 0.0263157894736842 2.77118644067797 0.304373684595298 0.519588294213454 GO:0042887 amide transmembrane transporter activity 1/177 38/18639 0.0263157894736842 2.77118644067797 0.304373684595298 0.519588294213454 GO:0001664 G protein-coupled receptor binding 4/177 297/18639 0.0134680134680135 1.41825029960623 0.312059756144798 0.519588294213454 GO:0005516 calmodulin binding 3/177 207/18639 0.0144927536231884 1.52616064848931 0.313929196625247 0.519588294213454 GO:0004532 RNA exonuclease activity 1/177 40/18639 0.025 2.63262711864407 0.317549678024294 0.519588294213454 GO:0015036 disulfide oxidoreductase activity 1/177 40/18639 0.025 2.63262711864407 0.317549678024294 0.519588294213454 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/177 40/18639 0.025 2.63262711864407 0.317549678024294 0.519588294213454 GO:0071855 neuropeptide receptor binding 1/177 40/18639 0.025 2.63262711864407 0.317549678024294 0.519588294213454 GO:0051015 actin filament binding 3/177 209/18639 0.0143540669856459 1.5115562403698 0.319122151265329 0.519588294213454 GO:0015108 chloride transmembrane transporter activity 2/177 121/18639 0.0165289256198347 1.7405799131531 0.31930484946166 0.519588294213454 GO:0031625 ubiquitin protein ligase binding 4/177 302/18639 0.0132450331125828 1.39476933438096 0.322783361195403 0.519588294213454 GO:0008528 G protein-coupled peptide receptor activity 2/177 122/18639 0.0163934426229508 1.72631286468463 0.322789782427077 0.519588294213454 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/177 122/18639 0.0163934426229508 1.72631286468463 0.322789782427077 0.519588294213454 GO:0001530 lipopolysaccharide binding 1/177 41/18639 0.024390243902439 2.56841670111616 0.324044312520219 0.519588294213454 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/177 41/18639 0.024390243902439 2.56841670111616 0.324044312520219 0.519588294213454 GO:0017080 sodium channel regulator activity 1/177 41/18639 0.024390243902439 2.56841670111616 0.324044312520219 0.519588294213454 GO:0042169 SH2 domain binding 1/177 41/18639 0.024390243902439 2.56841670111616 0.324044312520219 0.519588294213454 GO:0004520 DNA endonuclease activity 1/177 42/18639 0.0238095238095238 2.50726392251816 0.330477485801428 0.523138828587792 GO:0048487 beta-tubulin binding 1/177 42/18639 0.0238095238095238 2.50726392251816 0.330477485801428 0.523138828587792 GO:0051879 Hsp90 protein binding 1/177 42/18639 0.0238095238095238 2.50726392251816 0.330477485801428 0.523138828587792 GO:0048156 tau protein binding 1/177 43/18639 0.0232558139534884 2.44895545920378 0.336849776225321 0.530966596422964 GO:0043014 alpha-tubulin binding 1/177 44/18639 0.0227272727272727 2.39329738058552 0.343161756737696 0.533389858555293 GO:0001653 peptide receptor activity 2/177 128/18639 0.015625 1.64539194915254 0.343598967161983 0.533389858555293 GO:0035591 signaling adaptor activity 2/177 129/18639 0.0155038759689922 1.63263697280252 0.347048392629016 0.533389858555293 GO:0008009 chemokine activity 1/177 45/18639 0.0222222222222222 2.34011299435028 0.349413994923091 0.533389858555293 GO:0046915 transition metal ion transmembrane transporter activity 1/177 45/18639 0.0222222222222222 2.34011299435028 0.349413994923091 0.533389858555293 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/177 130/18639 0.0153846153846154 1.62007822685789 0.350491899878478 0.533389858555293 GO:0004180 carboxypeptidase activity 1/177 46/18639 0.0217391304347826 2.28924097273397 0.355607053054672 0.533389858555293 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/177 132/18639 0.0151515151515152 1.59553158705701 0.357360371206535 0.533389858555293 GO:0044389 ubiquitin-like protein ligase binding 4/177 322/18639 0.0124223602484472 1.30813769870513 0.365861136121059 0.533389858555293 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/177 48/18639 0.0208333333333333 2.19385593220339 0.367817851988235 0.533389858555293 GO:0140693 molecular condensate scaffold activity 1/177 48/18639 0.0208333333333333 2.19385593220339 0.367817851988235 0.533389858555293 GO:0044325 transmembrane transporter binding 2/177 136/18639 0.0147058823529412 1.54860418743769 0.371017856243454 0.533389858555293 GO:0001222 transcription corepressor binding 1/177 49/18639 0.0204081632653061 2.14908336215842 0.37383669122217 0.533389858555293 GO:0005004 GPI-linked ephrin receptor activity 1/177 49/18639 0.0204081632653061 2.14908336215842 0.37383669122217 0.533389858555293 GO:0005008 hepatocyte growth factor receptor activity 1/177 49/18639 0.0204081632653061 2.14908336215842 0.37383669122217 0.533389858555293 GO:0005009 insulin receptor activity 1/177 49/18639 0.0204081632653061 2.14908336215842 0.37383669122217 0.533389858555293 GO:0005011 macrophage colony-stimulating factor receptor activity 1/177 49/18639 0.0204081632653061 2.14908336215842 0.37383669122217 0.533389858555293 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/177 49/18639 0.0204081632653061 2.14908336215842 0.37383669122217 0.533389858555293 GO:0005020 stem cell factor receptor activity 1/177 49/18639 0.0204081632653061 2.14908336215842 0.37383669122217 0.533389858555293 GO:0008288 boss receptor activity 1/177 49/18639 0.0204081632653061 2.14908336215842 0.37383669122217 0.533389858555293 GO:0036332 placental growth factor receptor activity 1/177 49/18639 0.0204081632653061 2.14908336215842 0.37383669122217 0.533389858555293 GO:0038062 protein tyrosine kinase collagen receptor activity 1/177 49/18639 0.0204081632653061 2.14908336215842 0.37383669122217 0.533389858555293 GO:0060175 brain-derived neurotrophic factor receptor activity 1/177 49/18639 0.0204081632653061 2.14908336215842 0.37383669122217 0.533389858555293 GO:0005006 epidermal growth factor receptor activity 1/177 50/18639 0.02 2.10610169491525 0.379798547362766 0.533389858555293 GO:0005007 fibroblast growth factor receptor activity 1/177 50/18639 0.02 2.10610169491525 0.379798547362766 0.533389858555293 GO:0005017 platelet-derived growth factor receptor activity 1/177 50/18639 0.02 2.10610169491525 0.379798547362766 0.533389858555293 GO:0005019 platelet-derived growth factor beta-receptor activity 1/177 50/18639 0.02 2.10610169491525 0.379798547362766 0.533389858555293 GO:0032813 tumor necrosis factor receptor superfamily binding 1/177 50/18639 0.02 2.10610169491525 0.379798547362766 0.533389858555293 GO:0070851 growth factor receptor binding 2/177 139/18639 0.0143884892086331 1.5151810754786 0.381185818576317 0.533389858555293 GO:0005010 insulin-like growth factor receptor activity 1/177 51/18639 0.0196078431372549 2.06480558325025 0.385703956858531 0.533389858555293 GO:0005021 vascular endothelial growth factor receptor activity 1/177 51/18639 0.0196078431372549 2.06480558325025 0.385703956858531 0.533389858555293 GO:0005030 neurotrophin receptor activity 1/177 51/18639 0.0196078431372549 2.06480558325025 0.385703956858531 0.533389858555293 GO:0030544 Hsp70 protein binding 1/177 51/18639 0.0196078431372549 2.06480558325025 0.385703956858531 0.533389858555293 GO:0030159 signaling receptor complex adaptor activity 1/177 52/18639 0.0192307692307692 2.02509778357236 0.391553451136347 0.535555402438883 GO:0005003 ephrin receptor activity 1/177 53/18639 0.0188679245283019 1.98688839142949 0.397347556648203 0.535555402438883 GO:0005005 transmembrane-ephrin receptor activity 1/177 53/18639 0.0188679245283019 1.98688839142949 0.397347556648203 0.535555402438883 GO:0005246 calcium channel regulator activity 1/177 53/18639 0.0188679245283019 1.98688839142949 0.397347556648203 0.535555402438883 GO:0016860 intramolecular oxidoreductase activity 1/177 53/18639 0.0188679245283019 1.98688839142949 0.397347556648203 0.535555402438883 GO:0038064 collagen receptor activity 1/177 53/18639 0.0188679245283019 1.98688839142949 0.397347556648203 0.535555402438883 GO:0051018 protein kinase A binding 1/177 53/18639 0.0188679245283019 1.98688839142949 0.397347556648203 0.535555402438883 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/177 54/18639 0.0185185185185185 1.95009416195857 0.403086794917506 0.537449059890008 GO:0050661 NADP binding 1/177 54/18639 0.0185185185185185 1.95009416195857 0.403086794917506 0.537449059890008 GO:0051287 NAD binding 1/177 54/18639 0.0185185185185185 1.95009416195857 0.403086794917506 0.537449059890008 GO:0008509 monoatomic anion transmembrane transporter activity 2/177 149/18639 0.0134228187919463 1.41349107041292 0.414554710004137 0.550765543291211 GO:0004601 peroxidase activity 1/177 57/18639 0.0175438596491228 1.84745762711864 0.419980448535894 0.555988351798408 GO:0008408 3'-5' exonuclease activity 1/177 58/18639 0.0172413793103448 1.8156049094097 0.425505336094238 0.560572642337094 GO:0001786 phosphatidylserine binding 1/177 59/18639 0.0169491525423729 1.78483194484344 0.430977891689272 0.560572642337094 GO:0004879 nuclear receptor activity 1/177 59/18639 0.0169491525423729 1.78483194484344 0.430977891689272 0.560572642337094 GO:0015459 potassium channel regulator activity 1/177 59/18639 0.0169491525423729 1.78483194484344 0.430977891689272 0.560572642337094 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/177 59/18639 0.0169491525423729 1.78483194484344 0.430977891689272 0.560572642337094 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/177 60/18639 0.0166666666666667 1.75508474576271 0.436398608221618 0.561731080479038 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/177 60/18639 0.0166666666666667 1.75508474576271 0.436398608221618 0.561731080479038 GO:0098531 ligand-modulated transcription factor activity 1/177 60/18639 0.0166666666666667 1.75508474576271 0.436398608221618 0.561731080479038 GO:1901682 sulfur compound transmembrane transporter activity 1/177 63/18639 0.0158730158730159 1.67150928167877 0.452354583463024 0.580261741545672 GO:0003730 mRNA 3'-UTR binding 3/177 262/18639 0.0114503816793893 1.20578341311942 0.454580273702337 0.581112927207112 GO:0046982 protein heterodimerization activity 4/177 369/18639 0.010840108401084 1.14151853382941 0.46584163041371 0.591647276739451 GO:0015103 inorganic anion transmembrane transporter activity 2/177 165/18639 0.0121212121212121 1.27642526964561 0.46600175291575 0.591647276739451 GO:0008235 metalloexopeptidase activity 1/177 66/18639 0.0151515151515152 1.59553158705701 0.467861313273755 0.591987784142302 GO:0016500 protein-hormone receptor activity 1/177 67/18639 0.0149253731343284 1.57171768277258 0.47293257518893 0.594361209359061 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/177 67/18639 0.0149253731343284 1.57171768277258 0.47293257518893 0.594361209359061 GO:0042379 chemokine receptor binding 1/177 72/18639 0.0138888888888889 1.46257062146893 0.497577001530104 0.623227759492252 GO:0043539 protein serine/threonine kinase activator activity 1/177 73/18639 0.0136986301369863 1.4425354074762 0.502366621324857 0.625560114851589 GO:0043021 ribonucleoprotein complex binding 2/177 177/18639 0.0112994350282486 1.18988796322896 0.502802350378025 0.625560114851589 GO:0003684 damaged DNA binding 1/177 74/18639 0.0135135135135135 1.42304168575355 0.50711083698927 0.628817437866695 GO:0051536 iron-sulfur cluster binding 1/177 76/18639 0.0131578947368421 1.38559322033898 0.516464763894553 0.638288678301574 GO:0051540 metal cluster binding 1/177 77/18639 0.012987012987013 1.36759850319172 0.521075319127579 0.641854366607481 GO:0019199 transmembrane receptor protein kinase activity 1/177 78/18639 0.0128205128205128 1.35006518904824 0.525642158289007 0.645342847800365 GO:0016835 carbon-oxygen lyase activity 1/177 79/18639 0.0126582278481013 1.33297575627548 0.530165693550191 0.648755388160102 GO:0004527 exonuclease activity 1/177 84/18639 0.0119047619047619 1.25363196125908 0.552147968870242 0.671238707254019 GO:0051117 ATPase binding 1/177 84/18639 0.0119047619047619 1.25363196125908 0.552147968870242 0.671238707254019 GO:0016209 antioxidant activity 1/177 86/18639 0.0116279069767442 1.22447772960189 0.560651751110421 0.679356519260836 GO:0008081 phosphoric diester hydrolase activity 1/177 87/18639 0.0114942528735632 1.2104032729398 0.564843237126346 0.682213260425328 GO:0004197 cysteine-type endopeptidase activity 1/177 88/18639 0.0113636363636364 1.19664869029276 0.56899495915247 0.685003640144721 GO:0003727 single-stranded RNA binding 1/177 89/18639 0.0112359550561798 1.18320319939059 0.573107292300549 0.687728750760658 GO:0072341 modified amino acid binding 1/177 91/18639 0.010989010989011 1.15719873346992 0.581215274849578 0.695215698533901 GO:0052689 carboxylic ester hydrolase activity 1/177 92/18639 0.0108695652173913 1.14462048636699 0.585211657012163 0.697752360283733 GO:0004518 nuclease activity 2/177 209/18639 0.00956937799043062 1.00770416024653 0.592627841575541 0.702642851795463 GO:0016410 N-acyltransferase activity 1/177 94/18639 0.0106382978723404 1.12026685899748 0.593091009311224 0.702642851795463 GO:0043130 ubiquitin binding 1/177 100/18639 0.01 1.05305084745763 0.61584711564833 0.727286117527551 GO:0008238 exopeptidase activity 1/177 102/18639 0.00980392156862745 1.03240279162512 0.623147648315655 0.733578877131087 GO:0008013 beta-catenin binding 1/177 106/18639 0.00943396226415094 0.993444195714743 0.637337390511146 0.747916433028853 GO:0000287 magnesium ion binding 2/177 230/18639 0.00869565217391304 0.915696389093589 0.644733659457353 0.75286973579289 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 3/177 349/18639 0.00859598853868195 0.905201301539508 0.647138794403448 0.75286973579289 GO:0004620 phospholipase activity 1/177 109/18639 0.00917431192660551 0.966101694915254 0.647629880251949 0.75286973579289 GO:0043022 ribosome binding 1/177 112/18639 0.00892857142857143 0.94022397094431 0.657631869219389 0.762115437226207 GO:0035401 histone H3Y41 kinase activity 1/177 115/18639 0.00869565217391304 0.915696389093589 0.667351511387482 0.768590595158338 GO:0140801 histone H2AXY142 kinase activity 1/177 115/18639 0.00869565217391304 0.915696389093589 0.667351511387482 0.768590595158338 GO:0032182 ubiquitin-like protein binding 1/177 120/18639 0.00833333333333333 0.877542372881356 0.682944905736575 0.781814459801937 GO:0140297 DNA-binding transcription factor binding 4/177 488/18639 0.00819672131147541 0.863156432342317 0.684572803555848 0.781814459801937 GO:0004540 RNA nuclease activity 1/177 121/18639 0.00826446280991736 0.870289956576551 0.685975239538866 0.781814459801937 GO:0140104 molecular carrier activity 2/177 249/18639 0.00803212851405622 0.845823973861548 0.687240129987187 0.781814459801937 GO:0004519 endonuclease activity 1/177 127/18639 0.0078740157480315 0.829173895635927 0.703561856995502 0.797942106104655 GO:0015631 tubulin binding 3/177 385/18639 0.00779220779220779 0.820559101915034 0.711391466604379 0.800175738271495 GO:0016298 lipase activity 1/177 130/18639 0.00769230769230769 0.810039113428944 0.711984326257701 0.800175738271495 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/177 130/18639 0.00769230769230769 0.810039113428944 0.711984326257701 0.800175738271495 GO:0031072 heat shock protein binding 1/177 131/18639 0.00763358778625954 0.80385560874628 0.714738595761855 0.800851679588584 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/177 268/18639 0.00746268656716418 0.785858841386289 0.725506515337902 0.810475746863962 GO:0004713 protein tyrosine kinase activity 1/177 140/18639 0.00714285714285714 0.752179176755448 0.738377641892556 0.821291313791247 GO:0008017 microtubule binding 2/177 276/18639 0.0072463768115942 0.763080324244657 0.740403851993545 0.821291313791247 GO:0020037 heme binding 1/177 142/18639 0.00704225352112676 0.741585103843399 0.743360274649514 0.821291313791247 GO:0001217 DNA-binding transcription repressor activity 2/177 278/18639 0.00719424460431655 0.7575905377393 0.744019281579705 0.821291313791247 GO:0035091 phosphatidylinositol binding 2/177 284/18639 0.00704225352112676 0.741585103843399 0.754609251715477 0.830516691237152 GO:0019842 vitamin binding 1/177 150/18639 0.00666666666666667 0.702033898305085 0.762364723870491 0.836577219114521 GO:0046906 tetrapyrrole binding 1/177 152/18639 0.00657894736842105 0.692796610169492 0.766892955570883 0.839071116095201 GO:0022804 active transmembrane transporter activity 3/177 457/18639 0.00656455142231947 0.691280643845269 0.812493663780498 0.886356724124179 GO:0005319 lipid transporter activity 1/177 178/18639 0.00561797752808989 0.591601599695296 0.818510708710177 0.890309893684754 GO:0016853 isomerase activity 1/177 180/18639 0.00555555555555556 0.585028248587571 0.821974277236472 0.891470644699614 GO:1901981 phosphatidylinositol phosphate binding 1/177 185/18639 0.00540540540540541 0.56921667430142 0.83034832440153 0.89535523453228 GO:0140097 catalytic activity, acting on DNA 2/177 336/18639 0.00595238095238095 0.62681598062954 0.831551630571306 0.89535523453228 GO:0008234 cysteine-type peptidase activity 1/177 187/18639 0.0053475935828877 0.563128795431886 0.833587204344263 0.89535523453228 GO:0140597 protein carrier chaperone 1/177 188/18639 0.00531914893617021 0.560133429498738 0.835183511781455 0.89535523453228 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3/177 484/18639 0.00619834710743802 0.652717467432414 0.841880936643699 0.899941690894988 GO:0001216 DNA-binding transcription activator activity 3/177 491/18639 0.00610997963340122 0.6434119230902 0.848822755690806 0.904762364232034 GO:0016829 lyase activity 1/177 200/18639 0.005 0.526525423728814 0.853191857505705 0.905689635372097 GO:0005543 phospholipid binding 3/177 497/18639 0.00603621730382294 0.635644374722914 0.854561994665608 0.905689635372097 GO:0005525 GTP binding 2/177 378/18639 0.00529100529100529 0.557169760559591 0.877103793743544 0.926939236569882 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/177 229/18639 0.00436681222707424 0.459847531640885 0.889037657917138 0.936889543187465 GO:0019001 guanyl nucleotide binding 2/177 400/18639 0.005 0.526525423728814 0.896175452416841 0.939090896617084 GO:0032561 guanyl ribonucleotide binding 2/177 400/18639 0.005 0.526525423728814 0.896175452416841 0.939090896617084 GO:0003713 transcription coactivator activity 1/177 256/18639 0.00390625 0.411347987288136 0.914530250726392 0.955632733905106 GO:0008514 organic anion transmembrane transporter activity 1/177 269/18639 0.00371747211895911 0.391468716526999 0.924634866607915 0.962286491816016 GO:0005096 GTPase activator activity 1/177 271/18639 0.003690036900369 0.388579648508349 0.926080236528337 0.962286491816016 GO:0005216 monoatomic ion channel activity 2/177 448/18639 0.00446428571428571 0.470111985472155 0.928658200435349 0.962286491816016 GO:0031267 small GTPase binding 1/177 283/18639 0.00353356890459364 0.372102772953225 0.934191526648199 0.965331244203139 GO:0051020 GTPase binding 1/177 315/18639 0.00317460317460317 0.334301856335755 0.951748643735734 0.980749294929898 GO:0003924 GTPase activity 1/177 331/18639 0.00302114803625378 0.318142249987199 0.958691952579059 0.985175155688977 GO:0141003 histone H2AX kinase activity 1/177 354/18639 0.00282485875706215 0.297471990807239 0.966967938755903 0.985634680073076 GO:0140996 histone H3 kinase activity 1/177 357/18639 0.00280112044817927 0.294972226178607 0.967917992059078 0.985634680073076 GO:0035173 histone kinase activity 1/177 360/18639 0.00277777777777778 0.292514124293785 0.968840870309341 0.985634680073076 GO:0042578 phosphoric ester hydrolase activity 1/177 363/18639 0.00275482093663912 0.290096652192184 0.96973734652351 0.985634680073076 GO:0140098 catalytic activity, acting on RNA 1/177 387/18639 0.00258397932816537 0.272106162133754 0.976044505232721 0.989342114295837 GO:0046873 metal ion transmembrane transporter activity 1/177 450/18639 0.00222222222222222 0.234011299435028 0.987048402912355 0.991744880217514 GO:0030695 GTPase regulator activity 1/177 489/18639 0.00204498977505112 0.215347821565977 0.991158606611291 0.991744880217514 GO:0060589 nucleoside-triphosphatase regulator activity 1/177 490/18639 0.00204081632653061 0.214908336215842 0.991244828464173 0.991744880217514 GO:0003712 transcription coregulator activity 1/177 495/18639 0.00202020202020202 0.212737544940935 0.991663555778181 0.991744880217514 GO:0016755 aminoacyltransferase activity 1/177 496/18639 0.00201612903225806 0.212308638600328 0.991744880217514 0.991744880217514