ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	40/649	175/18639	0.228571428571429	6.56447281532027	9.12208392277746e-22	7.88148050927972e-19
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	19/649	68/18639	0.279411764705882	8.02458533490438	1.03205053046738e-12	4.45845829161909e-10
GO:0009055	electron transfer activity	22/649	116/18639	0.189655172413793	5.44681472822911	7.53262867530201e-11	2.16939705848698e-08
GO:0022853	active monoatomic ion transmembrane transporter activity	21/649	118/18639	0.177966101694915	5.11110966023348	6.97047274625629e-10	1.2172541597538e-07
GO:0008137	NADH dehydrogenase (ubiquinone) activity	13/649	41/18639	0.317073170731707	9.10620466759367	7.04429490598262e-10	1.2172541597538e-07
GO:0003954	NADH dehydrogenase activity	13/649	44/18639	0.295454545454545	8.48532707662138	1.88497580783169e-09	2.71436516327763e-07
GO:0042605	peptide antigen binding	13/649	45/18639	0.288888888888889	8.29676425269646	2.56703545992926e-09	3.16845519625555e-07
GO:0015078	proton transmembrane transporter activity	25/649	185/18639	0.135135135135135	3.88102277932786	6.67562922283727e-09	7.11950039626653e-07
GO:0016651	oxidoreductase activity, acting on NAD(P)H	17/649	88/18639	0.193181818181818	5.54809847317551	8.0825352062528e-09	7.11950039626653e-07
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	14/649	58/18639	0.241379310344828	6.93230965410977	8.24016249567886e-09	7.11950039626653e-07
GO:0023026	MHC class II protein complex binding	10/649	27/18639	0.37037037037037	10.6368772470467	1.20697469130581e-08	9.48023757534745e-07
GO:0023023	MHC protein complex binding	11/649	37/18639	0.297297297297297	8.5382501145213	3.14008185741518e-08	2.26085893733893e-06
GO:0042277	peptide binding	28/649	249/18639	0.112449799196787	3.22950971838046	5.04763258443445e-08	3.35473427150105e-06
GO:0045296	cadherin binding	32/649	334/18639	0.0958083832335329	2.75157543157137	2.45608173674339e-07	1.51575330039021e-05
GO:0015399	primary active transmembrane transporter activity	21/649	166/18639	0.126506024096386	3.63319843317801	3.34875958427378e-07	1.9288855205417e-05
GO:0005201	extracellular matrix structural constituent	21/649	168/18639	0.125	3.58994607087827	4.10166142654788e-07	2.21489717033585e-05
GO:0005125	cytokine activity	24/649	234/18639	0.102564102564103	2.94559677610525	2.3854717503988e-06	0.000121238093667327
GO:0050840	extracellular matrix binding	12/649	67/18639	0.17910447761194	5.14380332543753	2.97913737803117e-06	0.000142998594145496
GO:0019838	growth factor binding	17/649	136/18639	0.125	3.58994607087827	5.14704766800445e-06	0.00023405522027136
GO:0031625	ubiquitin protein ligase binding	27/649	302/18639	0.0894039735099338	2.56764354738314	7.78590361335546e-06	0.000336351036096956
GO:0019843	rRNA binding	11/649	65/18639	0.169230769230769	4.86023468057366	1.35530592119613e-05	0.000557611579006408
GO:0042608	T cell receptor binding	5/649	11/18639	0.454545454545455	13.0543493486483	1.95562380964426e-05	0.000768026805242109
GO:0044389	ubiquitin-like protein ligase binding	27/649	322/18639	0.0838509316770186	2.40816258170717	2.47077997566202e-05	0.000928153869118254
GO:0140375	immune receptor activity	17/649	156/18639	0.108974358974359	3.12969657461183	3.19696075979907e-05	0.00115090587352767
GO:0003779	actin binding	33/649	443/18639	0.0744920993227991	2.13938095420285	3.66135347260989e-05	0.00126536376013398
GO:0019955	cytokine binding	16/649	144/18639	0.111111111111111	3.19106317411402	4.27444428974134e-05	0.00142043071782174
GO:0005178	integrin binding	17/649	161/18639	0.105590062111801	3.03250102881643	4.79058895759532e-05	0.0015329884664305
GO:0070325	lipoprotein particle receptor binding	7/649	31/18639	0.225806451612903	6.48506386997366	7.6151918436049e-05	0.00234983062602665
GO:0008201	heparin binding	17/649	172/18639	0.0988372093023256	2.83856200953166	0.000109601006451848	0.00326535412325505
GO:0005539	glycosaminoglycan binding	21/649	242/18639	0.0867768595041322	2.49219396656012	0.000119213296031825	0.00343334292571657
GO:0004601	peroxidase activity	9/649	57/18639	0.157894736842105	4.5346687211094	0.000143584126090289	0.00400182854651643
GO:0005518	collagen binding	10/649	72/18639	0.138888888888889	3.98882896764253	0.000187003042970719	0.00493588257011055
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	9/649	59/18639	0.152542372881356	4.38095113734298	0.000188523292608389	0.00493588257011055
GO:0032395	MHC class II receptor activity	4/649	10/18639	0.4	11.4878274268105	0.000258623433116902	0.00657207782979421
GO:0035615	clathrin adaptor activity	5/649	18/18639	0.277777777777778	7.97765793528505	0.000296040090542324	0.00710496217301577
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	5/649	18/18639	0.277777777777778	7.97765793528505	0.000296040090542324	0.00710496217301577
GO:0003823	antigen binding	16/649	174/18639	0.0919540229885057	2.64087986823229	0.00039373711229932	0.00882841433653724
GO:1990948	ubiquitin ligase inhibitor activity	4/649	11/18639	0.363636363636364	10.4434794789186	0.000395233258842879	0.00882841433653724
GO:0038024	cargo receptor activity	9/649	65/18639	0.138461538461538	3.97655564774209	0.000398504813802028	0.00882841433653724
GO:0008135	translation factor activity, RNA binding	10/649	83/18639	0.120481927710843	3.46018898397906	0.000602472034333922	0.0130133959416127
GO:0140312	cargo adaptor activity	5/649	21/18639	0.238095238095238	6.83799251595862	0.000644750641924611	0.0135869403566552
GO:0180051	translation factor activity	10/649	84/18639	0.119047619047619	3.41899625797931	0.000662983435234489	0.0136385163819666
GO:0097110	scaffold protein binding	9/649	70/18639	0.128571428571429	3.69251595861765	0.00069499004918787	0.0139644512208912
GO:0016209	antioxidant activity	10/649	86/18639	0.116279069767442	3.33948471709607	0.00079908976611731	0.0156912172255763
GO:0044548	S100 protein binding	4/649	14/18639	0.285714285714286	8.20559101915034	0.0011028970479351	0.0211756233203539
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	24/649	349/18639	0.0687679083094556	1.97498465790438	0.00125734829098046	0.023616280943633
GO:0004129	cytochrome-c oxidase activity	4/649	15/18639	0.266666666666667	7.65855161787365	0.00146279611186021	0.0263303300134837
GO:0055105	ubiquitin-protein transferase inhibitor activity	4/649	15/18639	0.266666666666667	7.65855161787365	0.00146279611186021	0.0263303300134837
GO:1901681	sulfur compound binding	20/649	275/18639	0.0727272727272727	2.08869589578372	0.00161048566523844	0.0283971349952247
GO:0050750	low-density lipoprotein particle receptor binding	5/649	26/18639	0.192307692307692	5.52299395519735	0.00180495643477879	0.0308568499334512
GO:0005200	structural constituent of cytoskeleton	11/649	112/18639	0.0982142857142857	2.82067191283293	0.00182141128079399	0.0308568499334512
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/649	16/18639	0.25	7.17989214175655	0.00189708958200017	0.0315208730547721
GO:0015252	proton channel activity	5/649	27/18639	0.185185185185185	5.31843862352337	0.00215252148417188	0.0350901615532925
GO:0001221	transcription coregulator binding	11/649	115/18639	0.0956521739130435	2.74708916728077	0.00224949755941368	0.0359919609506189
GO:0008429	phosphatidylethanolamine binding	4/649	17/18639	0.235294117647059	6.75754554518263	0.00241309191203384	0.0379074802181317
GO:0061134	peptidase regulator activity	17/649	226/18639	0.0752212389380531	2.16032152937808	0.00246509771648299	0.0380329361971661
GO:0140463	chromatin-protein adaptor activity	7/649	54/18639	0.12962962962963	3.72290703646636	0.00256820630094658	0.0389286007722429
GO:0051015	actin filament binding	16/649	209/18639	0.076555023923445	2.19862725871971	0.00273745513422709	0.0407786419995208
GO:0098641	cadherin binding involved in cell-cell adhesion	4/649	18/18639	0.222222222222222	6.38212634822804	0.00301796386103142	0.0441952673886635
GO:0042056	chemoattractant activity	6/649	42/18639	0.142857142857143	4.10279550957517	0.0031395553673866	0.0452095972903671
GO:0001968	fibronectin binding	5/649	30/18639	0.166666666666667	4.78659476117103	0.00348687022250617	0.0493776489785624
GO:0048156	tau protein binding	6/649	43/18639	0.13953488372093	4.00738166051528	0.00354330351466536	0.0493776489785624
GO:0140297	DNA-binding transcription factor binding	29/649	488/18639	0.0594262295081967	1.70669567304049	0.00376793262433622	0.0516745045623254
GO:0050815	phosphoserine residue binding	3/649	10/18639	0.3	8.61587057010786	0.0041981039957318	0.0566744039423792
GO:0008009	chemokine activity	6/649	45/18639	0.133333333333333	3.82927580893683	0.00446479514872927	0.0593474309000321
GO:0071813	lipoprotein particle binding	5/649	32/18639	0.15625	4.48743258859784	0.00465368517016842	0.0600117012988883
GO:0071814	protein-lipid complex binding	5/649	32/18639	0.15625	4.48743258859784	0.00465368517016842	0.0600117012988883
GO:0061135	endopeptidase regulator activity	14/649	184/18639	0.0760869565217391	2.18518456488243	0.00516863289282352	0.0656720414617577
GO:0140311	protein sequestering activity	5/649	33/18639	0.151515151515152	4.35144978288276	0.00533045690349692	0.0667465907916136
GO:0019864	IgG binding	3/649	11/18639	0.272727272727273	7.83260960918896	0.00562418052206514	0.0694184567294897
GO:0004857	enzyme inhibitor activity	25/649	416/18639	0.0600961538461538	1.72593561099917	0.00597036554811768	0.0726534624446996
GO:0046332	SMAD binding	8/649	79/18639	0.10126582278481	2.90831074096468	0.00614788006281363	0.0737745607537635
GO:0004896	cytokine receptor activity	9/649	96/18639	0.09375	2.69245955315871	0.00625217173599774	0.0739983065740007
GO:0004602	glutathione peroxidase activity	4/649	23/18639	0.173913043478261	4.99470757687412	0.00761012356057051	0.0883774346703882
GO:0004869	cysteine-type endopeptidase inhibitor activity	5/649	36/18639	0.138888888888889	3.98882896764253	0.00777394101267304	0.0883774346703882
GO:0055106	ubiquitin-protein transferase regulator activity	5/649	36/18639	0.138888888888889	3.98882896764253	0.00777394101267304	0.0883774346703882
GO:0001540	amyloid-beta binding	8/649	83/18639	0.0963855421686747	2.76815118718325	0.00824137433627952	0.0917896855785543
GO:0003743	translation initiation factor activity	6/649	51/18639	0.117647058823529	3.37877277259132	0.00828656883695282	0.0917896855785543
GO:0048027	mRNA 5'-UTR binding	4/649	24/18639	0.166666666666667	4.78659476117103	0.00888509628377629	0.095959039864784
GO:0050431	transforming growth factor beta binding	4/649	24/18639	0.166666666666667	4.78659476117103	0.00888509628377629	0.095959039864784
GO:0051018	protein kinase A binding	6/649	53/18639	0.113207547169811	3.25127191324825	0.00996632109649566	0.105857689482454
GO:0022804	active transmembrane transporter activity	26/649	457/18639	0.0568927789934354	1.63393606727064	0.0100872507853402	0.105857689482454
GO:0042974	nuclear retinoic acid receptor binding	4/649	25/18639	0.16	4.59513097072419	0.0102917198107942	0.105857689482454
GO:0120020	cholesterol transfer activity	4/649	25/18639	0.16	4.59513097072419	0.0102917198107942	0.105857689482454
GO:0004866	endopeptidase inhibitor activity	12/649	161/18639	0.0745341614906832	2.14058896151748	0.0107810335267599	0.109586034907301
GO:0019763	immunoglobulin receptor activity	3/649	14/18639	0.214285714285714	6.15419326436276	0.0114792438987169	0.115280451557019
GO:0019865	immunoglobulin binding	4/649	26/18639	0.153846153846154	4.41839516415788	0.0118347676973424	0.115280451557019
GO:0098632	cell-cell adhesion mediator activity	6/649	55/18639	0.109090909090909	3.13304384367558	0.0118749539219615	0.115280451557019
GO:0140313	molecular sequestering activity	6/649	55/18639	0.109090909090909	3.13304384367558	0.0118749539219615	0.115280451557019
GO:0033218	amide binding	16/649	247/18639	0.0647773279352227	1.86037691122437	0.0130656491022105	0.125430231381221
GO:0005044	scavenger receptor activity	4/649	27/18639	0.148148148148148	4.25475089881869	0.0135186366039808	0.128352769514718
GO:0097718	disordered domain specific binding	4/649	28/18639	0.142857142857143	4.10279550957517	0.0153473402213388	0.142798635326059
GO:0030414	peptidase inhibitor activity	12/649	169/18639	0.0710059171597633	2.0392593065344	0.0153706864413467	0.142798635326059
GO:0005126	cytokine receptor binding	17/649	275/18639	0.0618181818181818	1.77539151141616	0.0163764396855515	0.150523871152303
GO:0034450	ubiquitin-ubiquitin ligase activity	3/649	16/18639	0.1875	5.38491910631741	0.0167724942139151	0.150952447925236
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/649	16/18639	0.1875	5.38491910631741	0.0167724942139151	0.150952447925236
GO:0051861	glycolipid binding	4/649	29/18639	0.137931034482759	3.96131980234844	0.0173245057628029	0.154313123495482
GO:0030547	signaling receptor inhibitor activity	5/649	44/18639	0.113636363636364	3.26358733716207	0.0178560230332644	0.157424529599392
GO:0030169	low-density lipoprotein particle binding	3/649	17/18639	0.176470588235294	5.06815915888698	0.0198495089928897	0.171499757698567
GO:0048038	quinone binding	3/649	17/18639	0.176470588235294	5.06815915888698	0.0198495089928897	0.171499757698567
GO:0044325	transmembrane transporter binding	10/649	136/18639	0.0735294117647059	2.11173298286957	0.0206478886728769	0.17663144369669
GO:0099602	neurotransmitter receptor regulator activity	3/649	18/18639	0.166666666666667	4.78659476117103	0.0232158180192614	0.196651634986685
GO:0120015	sterol transfer activity	4/649	32/18639	0.125	3.58994607087827	0.0241772381035689	0.202807123509549
GO:0005543	phospholipid binding	26/649	497/18639	0.0523138832997988	1.50243215843598	0.0261977473311736	0.217642823982058
GO:0001222	transcription corepressor binding	5/649	49/18639	0.102040816326531	2.93056822112512	0.0272411253967204	0.224155546121585
GO:0048020	CCR chemokine receptor binding	5/649	50/18639	0.1	2.87195685670262	0.0294315025042202	0.23850580512047
GO:0008376	acetylgalactosaminyltransferase activity	4/649	34/18639	0.117647058823529	3.37877277259132	0.0295371772545027	0.23850580512047
GO:0042288	MHC class I protein binding	3/649	20/18639	0.15	4.30793528505393	0.0308155811872567	0.246524649498054
GO:0005080	protein kinase C binding	5/649	52/18639	0.0961538461538462	2.76149697759867	0.0341374264973057	0.270593912785983
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	4/649	36/18639	0.111111111111111	3.19106317411402	0.0355454603366975	0.274207836883095
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	4/649	36/18639	0.111111111111111	3.19106317411402	0.0355454603366975	0.274207836883095
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	4/649	36/18639	0.111111111111111	3.19106317411402	0.0355454603366975	0.274207836883095
GO:0016860	intramolecular oxidoreductase activity	5/649	53/18639	0.0943396226415094	2.70939326104021	0.0366552499765568	0.28026669008624
GO:0043394	proteoglycan binding	4/649	37/18639	0.108108108108108	3.10481822346229	0.0387949912466409	0.294025196816647
GO:0042379	chemokine receptor binding	6/649	72/18639	0.0833333333333333	2.39329738058552	0.0392219444178563	0.294676173713286
GO:0046906	tetrapyrrole binding	10/649	152/18639	0.0657894736842105	1.88944530046225	0.0401202602346527	0.298826765885689
GO:0003712	transcription coregulator activity	25/649	495/18639	0.0505050505050505	1.45048326096092	0.0411274967423682	0.303710745174411
GO:0051219	phosphoprotein binding	7/649	93/18639	0.0752688172043011	2.16168795665789	0.043502640469569	0.306662075516328
GO:0031491	nucleosome binding	6/649	74/18639	0.0810810810810811	2.32861366759672	0.0439233638080789	0.306662075516328
GO:0017134	fibroblast growth factor binding	3/649	23/18639	0.130434782608696	3.74603068265559	0.0443514427791445	0.306662075516328
GO:0004090	carbonyl reductase (NADPH) activity	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.306662075516328
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.306662075516328
GO:0031720	haptoglobin binding	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.306662075516328
GO:0043208	glycosphingolipid binding	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.306662075516328
GO:0099122	RNA polymerase II C-terminal domain binding	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.306662075516328
GO:0140940	histone H2A methyltransferase activity	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.306662075516328
GO:1990259	histone H2AQ104 methyltransferase activity	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.306662075516328
GO:0000217	DNA secondary structure binding	4/649	39/18639	0.102564102564103	2.94559677610525	0.045786351552785	0.306662075516328
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	4/649	39/18639	0.102564102564103	2.94559677610525	0.045786351552785	0.306662075516328
GO:0016504	peptidase activator activity	5/649	57/18639	0.087719298245614	2.51926040061633	0.0478451221858081	0.315775097308974
GO:0004867	serine-type endopeptidase inhibitor activity	7/649	95/18639	0.0736842105263158	2.11617873651772	0.0478779372077264	0.315775097308974
GO:0002020	protease binding	9/649	136/18639	0.0661764705882353	1.90055968458262	0.0483782163890959	0.316657416364991
GO:0098631	cell adhesion mediator activity	6/649	76/18639	0.0789473684210526	2.2673343605547	0.0489627291935706	0.318073669347707
GO:0042287	MHC protein binding	4/649	41/18639	0.0975609756097561	2.80190912849036	0.0534323606578701	0.319408178657441
GO:0099106	ion channel regulator activity	10/649	160/18639	0.0625	1.79497303543914	0.0534901035201263	0.319408178657441
GO:0140104	molecular carrier activity	14/649	249/18639	0.0562248995983936	1.61475485919023	0.0539260110254918	0.319408178657441
GO:0005114	type II transforming growth factor beta receptor binding	2/649	11/18639	0.181818181818182	5.22173973945931	0.0540666996808816	0.319408178657441
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/649	11/18639	0.181818181818182	5.22173973945931	0.0540666996808816	0.319408178657441
GO:0019107	myristoyltransferase activity	2/649	11/18639	0.181818181818182	5.22173973945931	0.0540666996808816	0.319408178657441
GO:0048185	activin binding	2/649	11/18639	0.181818181818182	5.22173973945931	0.0540666996808816	0.319408178657441
GO:0050998	nitric-oxide synthase binding	2/649	11/18639	0.181818181818182	5.22173973945931	0.0540666996808816	0.319408178657441
GO:0097493	structural molecule activity conferring elasticity	2/649	11/18639	0.181818181818182	5.22173973945931	0.0540666996808816	0.319408178657441
GO:0140031	phosphorylation-dependent protein binding	2/649	11/18639	0.181818181818182	5.22173973945931	0.0540666996808816	0.319408178657441
GO:0001786	phosphatidylserine binding	5/649	59/18639	0.0847457627118644	2.43386174296832	0.0541181869021524	0.319408178657441
GO:0015459	potassium channel regulator activity	5/649	59/18639	0.0847457627118644	2.43386174296832	0.0541181869021524	0.319408178657441
GO:0045309	protein phosphorylated amino acid binding	5/649	59/18639	0.0847457627118644	2.43386174296832	0.0541181869021524	0.319408178657441
GO:0019199	transmembrane receptor protein kinase activity	6/649	78/18639	0.0769230769230769	2.20919758207894	0.0543437526188007	0.319408178657441
GO:0015271	outward rectifier potassium channel activity	3/649	25/18639	0.12	3.44634822804314	0.0547534742383624	0.319641903661791
GO:0008083	growth factor activity	10/649	162/18639	0.0617283950617284	1.77281287450779	0.0572432255201717	0.329001239986522
GO:0008307	structural constituent of muscle	4/649	42/18639	0.0952380952380952	2.73519700638345	0.0574990593032	0.329001239986522
GO:0016859	cis-trans isomerase activity	4/649	42/18639	0.0952380952380952	2.73519700638345	0.0574990593032	0.329001239986522
GO:0005516	calmodulin binding	12/649	207/18639	0.0579710144927536	1.66490252562471	0.0588572601038975	0.334557057432681
GO:0034237	protein kinase A regulatory subunit binding	3/649	26/18639	0.115384615384615	3.31379637311841	0.0603515663958868	0.336636352043269
GO:0050681	nuclear androgen receptor binding	3/649	26/18639	0.115384615384615	3.31379637311841	0.0603515663958868	0.336636352043269
GO:0020037	heme binding	9/649	142/18639	0.0633802816901408	1.82025434579743	0.0603919381559106	0.336636352043269
GO:0005078	MAP-kinase scaffold activity	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.338233045323713
GO:0017166	vinculin binding	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.338233045323713
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.338233045323713
GO:0035259	nuclear glucocorticoid receptor binding	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.338233045323713
GO:0036009	protein-glutamine N-methyltransferase activity	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.338233045323713
GO:0070008	serine-type exopeptidase activity	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.338233045323713
GO:0097371	MDM2/MDM4 family protein binding	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.338233045323713
GO:0019903	protein phosphatase binding	9/649	144/18639	0.0625	1.79497303543914	0.0647851513646056	0.343401047724044
GO:0016247	channel regulator activity	10/649	168/18639	0.0595238095238095	1.70949812898965	0.0695201179920438	0.366252328933694
GO:0046625	sphingolipid binding	3/649	28/18639	0.107142857142857	3.07709663218138	0.0723086837076993	0.378634561960316
GO:0008035	high-density lipoprotein particle binding	2/649	13/18639	0.153846153846154	4.41839516415788	0.0732665059974826	0.379055456178593
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/649	13/18639	0.153846153846154	4.41839516415788	0.0732665059974826	0.379055456178593
GO:0141108	transporter regulator activity	10/649	170/18639	0.0588235294117647	1.68938638629566	0.073956205728524	0.380346200889552
GO:0004629	phospholipase C activity	3/649	29/18639	0.103448275862069	2.97098985176133	0.0786530119321105	0.39974236652555
GO:0043236	laminin binding	3/649	29/18639	0.103448275862069	2.97098985176133	0.0786530119321105	0.39974236652555
GO:0005504	fatty acid binding	4/649	47/18639	0.0851063829787234	2.44421860144904	0.0802129719534135	0.403216838508106
GO:0005161	platelet-derived growth factor receptor binding	2/649	14/18639	0.142857142857143	4.10279550957517	0.0835643830139435	0.403216838508106
GO:0005344	oxygen carrier activity	2/649	14/18639	0.142857142857143	4.10279550957517	0.0835643830139435	0.403216838508106
GO:0008191	metalloendopeptidase inhibitor activity	2/649	14/18639	0.142857142857143	4.10279550957517	0.0835643830139435	0.403216838508106
GO:0019992	diacylglycerol binding	2/649	14/18639	0.142857142857143	4.10279550957517	0.0835643830139435	0.403216838508106
GO:0030983	mismatched DNA binding	2/649	14/18639	0.142857142857143	4.10279550957517	0.0835643830139435	0.403216838508106
GO:0032036	myosin heavy chain binding	2/649	14/18639	0.142857142857143	4.10279550957517	0.0835643830139435	0.403216838508106
GO:0140693	molecular condensate scaffold activity	4/649	48/18639	0.0833333333333333	2.39329738058552	0.0852180268135508	0.403216838508106
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/649	30/18639	0.1	2.87195685670262	0.0852307496169003	0.403216838508106
GO:0031210	phosphatidylcholine binding	3/649	30/18639	0.1	2.87195685670262	0.0852307496169003	0.403216838508106
GO:0048019	receptor antagonist activity	3/649	30/18639	0.1	2.87195685670262	0.0852307496169003	0.403216838508106
GO:0004197	cysteine-type endopeptidase activity	6/649	88/18639	0.0681818181818182	1.95815240229724	0.0864144536634387	0.403216838508106
GO:0032934	sterol binding	5/649	68/18639	0.0735294117647059	2.11173298286957	0.0879230409945137	0.403216838508106
GO:0005004	GPI-linked ephrin receptor activity	4/649	49/18639	0.0816326530612245	2.3444545769001	0.0903715291617136	0.403216838508106
GO:0005008	hepatocyte growth factor receptor activity	4/649	49/18639	0.0816326530612245	2.3444545769001	0.0903715291617136	0.403216838508106
GO:0005009	insulin receptor activity	4/649	49/18639	0.0816326530612245	2.3444545769001	0.0903715291617136	0.403216838508106
GO:0005011	macrophage colony-stimulating factor receptor activity	4/649	49/18639	0.0816326530612245	2.3444545769001	0.0903715291617136	0.403216838508106
GO:0005018	platelet-derived growth factor alpha-receptor activity	4/649	49/18639	0.0816326530612245	2.3444545769001	0.0903715291617136	0.403216838508106
GO:0005020	stem cell factor receptor activity	4/649	49/18639	0.0816326530612245	2.3444545769001	0.0903715291617136	0.403216838508106
GO:0008288	boss receptor activity	4/649	49/18639	0.0816326530612245	2.3444545769001	0.0903715291617136	0.403216838508106
GO:0036332	placental growth factor receptor activity	4/649	49/18639	0.0816326530612245	2.3444545769001	0.0903715291617136	0.403216838508106
GO:0038062	protein tyrosine kinase collagen receptor activity	4/649	49/18639	0.0816326530612245	2.3444545769001	0.0903715291617136	0.403216838508106
GO:0060175	brain-derived neurotrophic factor receptor activity	4/649	49/18639	0.0816326530612245	2.3444545769001	0.0903715291617136	0.403216838508106
GO:0042393	histone binding	13/649	247/18639	0.0526315789473684	1.5115562403698	0.0918962514255662	0.403216838508106
GO:0005523	tropomyosin binding	2/649	15/18639	0.133333333333333	3.82927580893683	0.0942691564244839	0.403216838508106
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/649	15/18639	0.133333333333333	3.82927580893683	0.0942691564244839	0.403216838508106
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/649	15/18639	0.133333333333333	3.82927580893683	0.0942691564244839	0.403216838508106
GO:0017081	chloride channel regulator activity	2/649	15/18639	0.133333333333333	3.82927580893683	0.0942691564244839	0.403216838508106
GO:0031386	protein tag activity	2/649	15/18639	0.133333333333333	3.82927580893683	0.0942691564244839	0.403216838508106
GO:0033130	acetylcholine receptor binding	2/649	15/18639	0.133333333333333	3.82927580893683	0.0942691564244839	0.403216838508106
GO:0141047	molecular tag activity	2/649	15/18639	0.133333333333333	3.82927580893683	0.0942691564244839	0.403216838508106
GO:0005006	epidermal growth factor receptor activity	4/649	50/18639	0.08	2.2975654853621	0.0956706619145391	0.403216838508106
GO:0005007	fibroblast growth factor receptor activity	4/649	50/18639	0.08	2.2975654853621	0.0956706619145391	0.403216838508106
GO:0005017	platelet-derived growth factor receptor activity	4/649	50/18639	0.08	2.2975654853621	0.0956706619145391	0.403216838508106
GO:0005019	platelet-derived growth factor beta-receptor activity	4/649	50/18639	0.08	2.2975654853621	0.0956706619145391	0.403216838508106
GO:0051087	protein-folding chaperone binding	8/649	134/18639	0.0597014925373134	1.71460110847918	0.0963783143264588	0.404227493097381
GO:0072341	modified amino acid binding	6/649	91/18639	0.0659340659340659	1.89359792749623	0.0976965973555111	0.407777102005611
GO:0003714	transcription corepressor activity	11/649	204/18639	0.053921568627451	1.54860418743769	0.101009824312555	0.412080854440818
GO:0005010	insulin-like growth factor receptor activity	4/649	51/18639	0.0784313725490196	2.25251518172754	0.101112431876682	0.412080854440818
GO:0005021	vascular endothelial growth factor receptor activity	4/649	51/18639	0.0784313725490196	2.25251518172754	0.101112431876682	0.412080854440818
GO:0005030	neurotrophin receptor activity	4/649	51/18639	0.0784313725490196	2.25251518172754	0.101112431876682	0.412080854440818
GO:0005048	signal sequence binding	4/649	51/18639	0.0784313725490196	2.25251518172754	0.101112431876682	0.412080854440818
GO:0005024	transforming growth factor beta receptor activity	2/649	16/18639	0.125	3.58994607087827	0.105340108168851	0.421223604360932
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/649	16/18639	0.125	3.58994607087827	0.105340108168851	0.421223604360932
GO:0022841	potassium ion leak channel activity	2/649	16/18639	0.125	3.58994607087827	0.105340108168851	0.421223604360932
GO:0055102	lipase inhibitor activity	2/649	16/18639	0.125	3.58994607087827	0.105340108168851	0.421223604360932
GO:0016922	nuclear receptor binding	8/649	137/18639	0.0583941605839416	1.67705509880445	0.105966657329454	0.421223604360932
GO:0030296	protein tyrosine kinase activator activity	3/649	33/18639	0.0909090909090909	2.61086986972965	0.106280955729957	0.421223604360932
GO:0030246	carbohydrate binding	14/649	280/18639	0.05	1.43597842835131	0.112410312769811	0.434751596909301
GO:0005003	ephrin receptor activity	4/649	53/18639	0.0754716981132075	2.16751460883217	0.112411105373813	0.434751596909301
GO:0005005	transmembrane-ephrin receptor activity	4/649	53/18639	0.0754716981132075	2.16751460883217	0.112411105373813	0.434751596909301
GO:0038064	collagen receptor activity	4/649	53/18639	0.0754716981132075	2.16751460883217	0.112411105373813	0.434751596909301
GO:0030295	protein kinase activator activity	8/649	139/18639	0.0575539568345324	1.65292480961302	0.112641311392571	0.434751596909301
GO:0015035	protein-disulfide reductase activity	3/649	34/18639	0.0882352941176471	2.53407957944349	0.113707773001775	0.434751596909301
GO:0019825	oxygen binding	3/649	34/18639	0.0882352941176471	2.53407957944349	0.113707773001775	0.434751596909301
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.434751596909301
GO:0005092	GDP-dissociation inhibitor activity	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.434751596909301
GO:0019198	transmembrane receptor protein phosphatase activity	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.434751596909301
GO:0030548	acetylcholine receptor regulator activity	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.434751596909301
GO:0038191	neuropilin binding	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.434751596909301
GO:0046965	nuclear retinoid X receptor binding	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.434751596909301
GO:0051787	misfolded protein binding	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.434751596909301
GO:0015485	cholesterol binding	4/649	54/18639	0.0740740740740741	2.12737544940935	0.118261254095139	0.436313766706863
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	4/649	54/18639	0.0740740740740741	2.12737544940935	0.118261254095139	0.436313766706863
GO:0031406	carboxylic acid binding	10/649	187/18639	0.053475935828877	1.53580580572333	0.118673304601982	0.436313766706863
GO:0031267	small GTPase binding	14/649	283/18639	0.049469964664311	1.42075604218504	0.119534881444327	0.436568297161112
GO:0003725	double-stranded RNA binding	5/649	75/18639	0.0666666666666667	1.91463790446841	0.120258396671695	0.436568297161112
GO:0044183	protein folding chaperone	5/649	75/18639	0.0666666666666667	1.91463790446841	0.120258396671695	0.436568297161112
GO:0140566	histone reader activity	3/649	35/18639	0.0857142857142857	2.4616773057451	0.121324776473752	0.438596681478332
GO:0043177	organic acid binding	10/649	189/18639	0.0529100529100529	1.51955389243525	0.124749538969632	0.448224370714761
GO:0019902	phosphatase binding	10/649	190/18639	0.0526315789473684	1.5115562403698	0.127850342130125	0.448224370714761
GO:0000400	four-way junction DNA binding	2/649	18/18639	0.111111111111111	3.19106317411402	0.128429234313944	0.448224370714761
GO:0003746	translation elongation factor activity	2/649	18/18639	0.111111111111111	3.19106317411402	0.128429234313944	0.448224370714761
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/649	18/18639	0.111111111111111	3.19106317411402	0.128429234313944	0.448224370714761
GO:0017075	syntaxin-1 binding	2/649	18/18639	0.111111111111111	3.19106317411402	0.128429234313944	0.448224370714761
GO:1901611	phosphatidylglycerol binding	2/649	18/18639	0.111111111111111	3.19106317411402	0.128429234313944	0.448224370714761
GO:0004033	aldo-keto reductase (NADPH) activity	3/649	36/18639	0.0833333333333333	2.39329738058552	0.129122896122575	0.448224370714761
GO:0005484	SNAP receptor activity	3/649	36/18639	0.0833333333333333	2.39329738058552	0.129122896122575	0.448224370714761
GO:0019207	kinase regulator activity	14/649	287/18639	0.0487804878048781	1.40095456424518	0.129433887459525	0.448224370714761
GO:0051082	unfolded protein binding	7/649	121/18639	0.0578512396694215	1.66146264437342	0.129694551711447	0.448224370714761
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/649	19/18639	0.105263157894737	3.0231124807396	0.140377199100574	0.471865130118274
GO:0022840	leak channel activity	2/649	19/18639	0.105263157894737	3.0231124807396	0.140377199100574	0.471865130118274
GO:0022842	narrow pore channel activity	2/649	19/18639	0.105263157894737	3.0231124807396	0.140377199100574	0.471865130118274
GO:0030506	ankyrin binding	2/649	19/18639	0.105263157894737	3.0231124807396	0.140377199100574	0.471865130118274
GO:0034987	immunoglobulin receptor binding	2/649	19/18639	0.105263157894737	3.0231124807396	0.140377199100574	0.471865130118274
GO:0043395	heparan sulfate proteoglycan binding	2/649	19/18639	0.105263157894737	3.0231124807396	0.140377199100574	0.471865130118274
GO:0097001	ceramide binding	2/649	19/18639	0.105263157894737	3.0231124807396	0.140377199100574	0.471865130118274
GO:0033293	monocarboxylic acid binding	5/649	79/18639	0.0632911392405063	1.81769421310292	0.140904170799207	0.471865130118274
GO:0017116	single-stranded DNA helicase activity	4/649	58/18639	0.0689655172413793	1.98065990117422	0.142915956070273	0.474920715556598
GO:0061980	regulatory RNA binding	4/649	58/18639	0.0689655172413793	1.98065990117422	0.142915956070273	0.474920715556598
GO:0019209	kinase activator activity	8/649	148/18639	0.0540540540540541	1.55240911173115	0.145380610022896	0.481259950420622
GO:0046982	protein heterodimerization activity	17/649	369/18639	0.046070460704607	1.32312375512045	0.147695567981778	0.487057140214718
GO:0016004	phospholipase activator activity	2/649	20/18639	0.1	2.87195685670262	0.152550712202053	0.497372888085185
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/649	20/18639	0.1	2.87195685670262	0.152550712202053	0.497372888085185
GO:0061608	nuclear import signal receptor activity	2/649	20/18639	0.1	2.87195685670262	0.152550712202053	0.497372888085185
GO:0042826	histone deacetylase binding	7/649	127/18639	0.0551181102362205	1.58296834621404	0.154885235413373	0.503085877432912
GO:0004714	transmembrane receptor protein tyrosine kinase activity	4/649	60/18639	0.0666666666666667	1.91463790446841	0.155941761941397	0.504620533023847
GO:0031490	chromatin DNA binding	7/649	128/18639	0.0546875	1.57060140600925	0.159289680092405	0.51353090895462
GO:0015036	disulfide oxidoreductase activity	3/649	40/18639	0.075	2.15396764252696	0.161943783047893	0.516307854440514
GO:0050997	quaternary ammonium group binding	3/649	40/18639	0.075	2.15396764252696	0.161943783047893	0.516307854440514
GO:0071949	FAD binding	3/649	40/18639	0.075	2.15396764252696	0.161943783047893	0.516307854440514
GO:0015026	coreceptor activity	4/649	61/18639	0.0655737704918033	1.88325039783778	0.162615209292494	0.516542429517332
GO:0051117	ATPase binding	5/649	84/18639	0.0595238095238095	1.70949812898965	0.168694657198699	0.533890783222255
GO:0017080	sodium channel regulator activity	3/649	41/18639	0.0731707317073171	2.10143184636777	0.17051047428921	0.537668064911961
GO:0031072	heat shock protein binding	7/649	131/18639	0.0534351145038168	1.53463343487926	0.172837012534773	0.543022468472887
GO:0016853	isomerase activity	9/649	180/18639	0.05	1.43597842835131	0.177137504782627	0.547109407383615
GO:0008093	cytoskeletal anchor activity	2/649	22/18639	0.0909090909090909	2.61086986972965	0.177455704527234	0.547109407383615
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/649	22/18639	0.0909090909090909	2.61086986972965	0.177455704527234	0.547109407383615
GO:0061133	endopeptidase activator activity	2/649	22/18639	0.0909090909090909	2.61086986972965	0.177455704527234	0.547109407383615
GO:0031492	nucleosomal DNA binding	3/649	42/18639	0.0714285714285714	2.05139775478759	0.179203660057365	0.547109407383615
GO:0035198	miRNA binding	3/649	42/18639	0.0714285714285714	2.05139775478759	0.179203660057365	0.547109407383615
GO:0048487	beta-tubulin binding	3/649	42/18639	0.0714285714285714	2.05139775478759	0.179203660057365	0.547109407383615
GO:0051879	Hsp90 protein binding	3/649	42/18639	0.0714285714285714	2.05139775478759	0.179203660057365	0.547109407383615
GO:0050660	flavin adenine dinucleotide binding	5/649	86/18639	0.0581395348837209	1.66974235854803	0.180370220284448	0.54873193776677
GO:0008081	phosphoric diester hydrolase activity	5/649	87/18639	0.0574712643678161	1.65054991764518	0.186318297530546	0.56483862830313
GO:0008200	ion channel inhibitor activity	3/649	43/18639	0.0697674418604651	2.00369083025764	0.188014433118092	0.56798765809102
GO:0070577	lysine-acetylated histone binding	2/649	23/18639	0.0869565217391304	2.49735378843706	0.190132300884195	0.570845481090236
GO:0120013	lipid transfer activity	4/649	65/18639	0.0615384615384615	1.76735806566315	0.190281827030079	0.570845481090236
GO:0001223	transcription coactivator binding	3/649	44/18639	0.0681818181818182	1.95815240229724	0.196933995136311	0.584711243291315
GO:0016248	channel inhibitor activity	3/649	44/18639	0.0681818181818182	1.95815240229724	0.196933995136311	0.584711243291315
GO:0030020	extracellular matrix structural constituent conferring tensile strength	3/649	44/18639	0.0681818181818182	1.95815240229724	0.196933995136311	0.584711243291315
GO:0015149	hexose transmembrane transporter activity	2/649	24/18639	0.0833333333333333	2.39329738058552	0.202924504263935	0.588344871422953
GO:0035035	histone acetyltransferase binding	2/649	24/18639	0.0833333333333333	2.39329738058552	0.202924504263935	0.588344871422953
GO:0055056	D-glucose transmembrane transporter activity	2/649	24/18639	0.0833333333333333	2.39329738058552	0.202924504263935	0.588344871422953
GO:0060229	lipase activator activity	2/649	24/18639	0.0833333333333333	2.39329738058552	0.202924504263935	0.588344871422953
GO:0070300	phosphatidic acid binding	2/649	24/18639	0.0833333333333333	2.39329738058552	0.202924504263935	0.588344871422953
GO:0140033	acetylation-dependent protein binding	2/649	24/18639	0.0833333333333333	2.39329738058552	0.202924504263935	0.588344871422953
GO:0140612	DNA damage sensor activity	2/649	24/18639	0.0833333333333333	2.39329738058552	0.202924504263935	0.588344871422953
GO:0016500	protein-hormone receptor activity	4/649	67/18639	0.0597014925373134	1.71460110847918	0.204639291942566	0.591332268355775
GO:0141110	transporter inhibitor activity	3/649	45/18639	0.0666666666666667	1.91463790446841	0.205953672240064	0.593146576051385
GO:0140597	protein carrier chaperone	9/649	188/18639	0.0478723404255319	1.37487296331508	0.209883197170684	0.594978979860646
GO:0051020	GTPase binding	14/649	315/18639	0.0444444444444444	1.27642526964561	0.210780021804036	0.594978979860646
GO:1990841	promoter-specific chromatin binding	4/649	68/18639	0.0588235294117647	1.68938638629566	0.211934057626819	0.594978979860646
GO:0035401	histone H3Y41 kinase activity	6/649	115/18639	0.0521739130434783	1.49841227306224	0.212226213097219	0.594978979860646
GO:0140801	histone H2AXY142 kinase activity	6/649	115/18639	0.0521739130434783	1.49841227306224	0.212226213097219	0.594978979860646
GO:0140713	histone chaperone activity	8/649	164/18639	0.0487804878048781	1.40095456424518	0.213421651474283	0.594978979860646
GO:0004180	carboxypeptidase activity	3/649	46/18639	0.0652173913043478	1.8730153413278	0.215064928946551	0.594978979860646
GO:0030276	clathrin binding	3/649	46/18639	0.0652173913043478	1.8730153413278	0.215064928946551	0.594978979860646
GO:0001848	complement binding	2/649	25/18639	0.08	2.2975654853621	0.215808941657463	0.594978979860646
GO:0005537	D-mannose binding	2/649	25/18639	0.08	2.2975654853621	0.215808941657463	0.594978979860646
GO:0008139	nuclear localization sequence binding	2/649	25/18639	0.08	2.2975654853621	0.215808941657463	0.594978979860646
GO:0015662	P-type ion transporter activity	2/649	25/18639	0.08	2.2975654853621	0.215808941657463	0.594978979860646
GO:0140358	P-type transmembrane transporter activity	2/649	25/18639	0.08	2.2975654853621	0.215808941657463	0.594978979860646
GO:0004713	protein tyrosine kinase activity	7/649	140/18639	0.05	1.43597842835131	0.216230786662318	0.594978979860646
GO:0061749	forked DNA-dependent helicase activity	3/649	47/18639	0.0638297872340425	1.83316395108678	0.224259380559719	0.611925252665269
GO:1990518	single-stranded 3'-5' DNA helicase activity	3/649	47/18639	0.0638297872340425	1.83316395108678	0.224259380559719	0.611925252665269
GO:0004435	phosphatidylinositol phospholipase C activity	2/649	26/18639	0.0769230769230769	2.20919758207894	0.228763722929261	0.611925252665269
GO:0005160	transforming growth factor beta receptor binding	2/649	26/18639	0.0769230769230769	2.20919758207894	0.228763722929261	0.611925252665269
GO:0008143	poly(A) binding	2/649	26/18639	0.0769230769230769	2.20919758207894	0.228763722929261	0.611925252665269
GO:0015145	monosaccharide transmembrane transporter activity	2/649	26/18639	0.0769230769230769	2.20919758207894	0.228763722929261	0.611925252665269
GO:0030247	polysaccharide binding	2/649	26/18639	0.0769230769230769	2.20919758207894	0.228763722929261	0.611925252665269
GO:0030507	spectrin binding	2/649	26/18639	0.0769230769230769	2.20919758207894	0.228763722929261	0.611925252665269
GO:0043548	phosphatidylinositol 3-kinase binding	2/649	26/18639	0.0769230769230769	2.20919758207894	0.228763722929261	0.611925252665269
GO:0042562	hormone binding	5/649	94/18639	0.0531914893617021	1.52763662590565	0.22977871556537	0.612743241507653
GO:0009378	four-way junction helicase activity	3/649	48/18639	0.0625	1.79497303543914	0.233528804142797	0.617030234799316
GO:0036121	double-stranded DNA helicase activity	3/649	48/18639	0.0625	1.79497303543914	0.233528804142797	0.617030234799316
GO:0043138	3'-5' DNA helicase activity	3/649	48/18639	0.0625	1.79497303543914	0.233528804142797	0.617030234799316
GO:0001664	G protein-coupled receptor binding	13/649	297/18639	0.0437710437710438	1.2570854928328	0.237465763957096	0.625519573350399
GO:0004364	glutathione transferase activity	2/649	27/18639	0.0740740740740741	2.12737544940935	0.241768366154012	0.629180326376706
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/649	27/18639	0.0740740740740741	2.12737544940935	0.241768366154012	0.629180326376706
GO:0008395	steroid hydroxylase activity	2/649	27/18639	0.0740740740740741	2.12737544940935	0.241768366154012	0.629180326376706
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/649	27/18639	0.0740740740740741	2.12737544940935	0.241768366154012	0.629180326376706
GO:0035254	glutamate receptor binding	3/649	49/18639	0.0612244897959184	1.75834093267507	0.242865148163302	0.63013660063992
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/649	122/18639	0.0491803278688525	1.41243779837834	0.252061029395266	0.650606290566668
GO:0032813	tumor necrosis factor receptor superfamily binding	3/649	50/18639	0.06	1.72317411402157	0.252260540902585	0.650606290566668
GO:0045499	chemorepellent activity	2/649	28/18639	0.0714285714285714	2.05139775478759	0.25480372634219	0.651313223353489
GO:0046966	nuclear thyroid hormone receptor binding	2/649	28/18639	0.0714285714285714	2.05139775478759	0.25480372634219	0.651313223353489
GO:0051119	sugar transmembrane transporter activity	2/649	28/18639	0.0714285714285714	2.05139775478759	0.25480372634219	0.651313223353489
GO:0140030	modification-dependent protein binding	8/649	173/18639	0.046242774566474	1.32807253489138	0.25621024231442	0.651313223353489
GO:0003678	DNA helicase activity	4/649	74/18639	0.0540540540540541	1.55240911173115	0.257057649494838	0.651313223353489
GO:0035064	methylated histone binding	4/649	74/18639	0.0540540540540541	1.55240911173115	0.257057649494838	0.651313223353489
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/649	52/18639	0.0576923076923077	1.6568981865592	0.271197927230484	0.661220608955611
GO:0030159	signaling receptor complex adaptor activity	3/649	52/18639	0.0576923076923077	1.6568981865592	0.271197927230484	0.661220608955611
GO:0017022	myosin binding	4/649	76/18639	0.0526315789473684	1.5115562403698	0.272513840283266	0.661220608955611
GO:0140034	methylation-dependent protein binding	4/649	76/18639	0.0526315789473684	1.5115562403698	0.272513840283266	0.661220608955611
GO:0000510	H3-H4 histone complex chaperone activity	7/649	151/18639	0.0463576158940397	1.33137072827274	0.273855205875738	0.661220608955611
GO:0140584	chromatin extrusion motor activity	7/649	151/18639	0.0463576158940397	1.33137072827274	0.273855205875738	0.661220608955611
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	7/649	151/18639	0.0463576158940397	1.33137072827274	0.273855205875738	0.661220608955611
GO:0140849	ATP-dependent H2AZ histone chaperone activity	7/649	151/18639	0.0463576158940397	1.33137072827274	0.273855205875738	0.661220608955611
GO:0019887	protein kinase regulator activity	11/649	255/18639	0.0431372549019608	1.23888334995015	0.276457722204879	0.661220608955611
GO:0015616	DNA translocase activity	7/649	152/18639	0.0460526315789474	1.32261171032357	0.279289743730378	0.661220608955611
GO:0140674	ATP-dependent histone chaperone activity	7/649	152/18639	0.0460526315789474	1.32261171032357	0.279289743730378	0.661220608955611
GO:0003724	RNA helicase activity	4/649	77/18639	0.051948051948052	1.49192563984552	0.280301167869654	0.661220608955611
GO:0003713	transcription coactivator activity	11/649	256/18639	0.04296875	1.23404396186441	0.280619911585572	0.661220608955611
GO:0017046	peptide hormone binding	3/649	53/18639	0.0566037735849057	1.62563595662412	0.280725136541884	0.661220608955611
GO:0001965	G-protein alpha-subunit binding	2/649	30/18639	0.0666666666666667	1.91463790446841	0.280896297251939	0.661220608955611
GO:0016769	transferase activity, transferring nitrogenous groups	2/649	30/18639	0.0666666666666667	1.91463790446841	0.280896297251939	0.661220608955611
GO:0008238	exopeptidase activity	5/649	102/18639	0.0490196078431373	1.40782198857972	0.282526543580551	0.661220608955611
GO:0061775	cohesin loader activity	7/649	153/18639	0.0457516339869281	1.31396718934107	0.284751137133975	0.661220608955611
GO:0050661	NADP binding	3/649	54/18639	0.0555555555555556	1.59553158705701	0.29028183550934	0.661220608955611
GO:0035591	signaling adaptor activity	6/649	129/18639	0.0465116279069767	1.33579388683843	0.293755822356067	0.661220608955611
GO:0005164	tumor necrosis factor receptor binding	2/649	31/18639	0.0645161290322581	1.85287539142104	0.293921305791079	0.661220608955611
GO:0004386	helicase activity	7/649	155/18639	0.0451612903225806	1.29701277399473	0.295749083039419	0.661220608955611
GO:0008186	ATP-dependent activity, acting on RNA	4/649	79/18639	0.0506329113924051	1.45415537048234	0.295974281693733	0.661220608955611
GO:0001094	TFIID-class transcription factor complex binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0003796	lysozyme activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0004955	prostaglandin receptor activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0005031	tumor necrosis factor receptor activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0005528	FK506 binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0008140	cAMP response element binding protein binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0008401	retinoic acid 4-hydroxylase activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0015187	glycine transmembrane transporter activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0015203	polyamine transmembrane transporter activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0030957	Tat protein binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0031419	cobalamin binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0031434	mitogen-activated protein kinase kinase binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0035374	chondroitin sulfate binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0042975	peroxisome proliferator activated receptor binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0043121	neurotrophin binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0045322	unmethylated CpG binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0051880	G-quadruplex DNA binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0070097	delta-catenin binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:1990757	ubiquitin ligase activator activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.661220608955611
GO:0048306	calcium-dependent protein binding	4/649	80/18639	0.05	1.43597842835131	0.303852233816792	0.668916553668832
GO:0031369	translation initiation factor binding	2/649	32/18639	0.0625	1.79497303543914	0.30691250586545	0.668916553668832
GO:0070717	poly-purine tract binding	2/649	32/18639	0.0625	1.79497303543914	0.30691250586545	0.668916553668832
GO:0140142	nucleocytoplasmic carrier activity	2/649	32/18639	0.0625	1.79497303543914	0.30691250586545	0.668916553668832
GO:0000149	SNARE binding	5/649	106/18639	0.0471698113207547	1.3546966305201	0.309736120148576	0.668916553668832
GO:0008094	ATP-dependent activity, acting on DNA	9/649	210/18639	0.0428571428571429	1.23083865287255	0.310165924670561	0.668916553668832
GO:0008237	metallopeptidase activity	8/649	184/18639	0.0434782608695652	1.24867689421853	0.31164639990058	0.668916553668832
GO:0001618	virus receptor activity	4/649	81/18639	0.0493827160493827	1.41825029960623	0.311752661408262	0.668916553668832
GO:0005179	hormone activity	6/649	132/18639	0.0454545454545455	1.30543493486483	0.312040718738508	0.668916553668832
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	6/649	132/18639	0.0454545454545455	1.30543493486483	0.312040718738508	0.668916553668832
GO:0140658	ATP-dependent chromatin remodeler activity	7/649	158/18639	0.0443037974683544	1.27238594917205	0.312413627407105	0.668916553668832
GO:0140272	exogenous protein binding	4/649	82/18639	0.0487804878048781	1.40095456424518	0.319671804106502	0.668916553668832
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	2/649	33/18639	0.0606060606060606	1.7405799131531	0.319856476841934	0.668916553668832
GO:0019956	chemokine binding	2/649	33/18639	0.0606060606060606	1.7405799131531	0.319856476841934	0.668916553668832
GO:0071889	14-3-3 protein binding	2/649	33/18639	0.0606060606060606	1.7405799131531	0.319856476841934	0.668916553668832
GO:0001851	complement component C3b binding	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.668916553668832
GO:0002162	dystroglycan binding	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.668916553668832
GO:0003953	NAD+ nucleosidase activity	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.668916553668832
GO:0004954	prostanoid receptor activity	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.668916553668832
GO:0008199	ferric iron binding	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.668916553668832
GO:0008432	JUN kinase binding	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.668916553668832
GO:0008526	phosphatidylinositol transfer activity	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.668916553668832
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.668916553668832
GO:0032794	GTPase activating protein binding	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.668916553668832
GO:0034713	type I transforming growth factor beta receptor binding	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.668916553668832
GO:0043522	leucine zipper domain binding	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.668916553668832
GO:0005496	steroid binding	5/649	108/18639	0.0462962962962963	1.32960965588084	0.323478372967524	0.668916553668832
GO:0003689	DNA clamp loader activity	7/649	160/18639	0.04375	1.2564811248074	0.323619351196264	0.668916553668832
GO:0004620	phospholipase activity	5/649	109/18639	0.0458715596330275	1.31741140215716	0.330375204607783	0.669398953502923
GO:0015020	glucuronosyltransferase activity	2/649	34/18639	0.0588235294117647	1.68938638629566	0.332740770831944	0.669398953502923
GO:0004860	protein kinase inhibitor activity	4/649	84/18639	0.0476190476190476	1.36759850319172	0.335551534985805	0.669398953502923
GO:0004222	metalloendopeptidase activity	5/649	110/18639	0.0454545454545455	1.30543493486483	0.337285945824458	0.669398953502923
GO:0004175	endopeptidase activity	16/649	405/18639	0.0395061728395062	1.13460023968499	0.338098048359535	0.669398953502923
GO:0005154	epidermal growth factor receptor binding	2/649	35/18639	0.0571428571428571	1.64111820383007	0.345553861399106	0.669398953502923
GO:0043015	gamma-tubulin binding	2/649	35/18639	0.0571428571428571	1.64111820383007	0.345553861399106	0.669398953502923
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0003995	acyl-CoA dehydrogenase activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0004859	phospholipase inhibitor activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0004875	complement receptor activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0005025	transforming growth factor beta receptor activity, type I	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0005026	transforming growth factor beta receptor activity, type II	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0005095	GTPase inhibitor activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0005527	macrolide binding	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0008179	adenylate cyclase binding	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0015166	polyol transmembrane transporter activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0016273	arginine N-methyltransferase activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0016274	protein-arginine N-methyltransferase activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0016361	activin receptor activity, type I	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0016362	activin receptor activity, type II	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0017002	activin receptor activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0035197	siRNA binding	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0035497	cAMP response element binding	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0045295	gamma-catenin binding	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0097677	STAT family protein binding	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.669398953502923
GO:0001098	basal transcription machinery binding	3/649	60/18639	0.05	1.43597842835131	0.347870520975477	0.669398953502923
GO:0001099	basal RNA polymerase II transcription machinery binding	3/649	60/18639	0.05	1.43597842835131	0.347870520975477	0.669398953502923
GO:0019905	syntaxin binding	3/649	61/18639	0.0491803278688525	1.41243779837834	0.357452692269424	0.686121729591312
GO:0000993	RNA polymerase II complex binding	2/649	36/18639	0.0555555555555556	1.59553158705701	0.358285094650668	0.686121729591312
GO:0004465	lipoprotein lipase activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0005035	death receptor activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0005172	vascular endothelial growth factor receptor binding	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0005542	folic acid binding	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0017154	semaphorin receptor activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0019855	calcium channel inhibitor activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0039706	co-receptor binding	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0043560	insulin receptor substrate binding	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0046974	histone H3K9 methyltransferase activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0070123	transforming growth factor beta receptor activity, type III	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0070700	BMP receptor binding	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0140333	glycerophospholipid flippase activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.686121729591312
GO:0017124	SH3 domain binding	5/649	115/18639	0.0434782608695652	1.24867689421853	0.371966051619761	0.689653795277841
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	4/649	89/18639	0.0449438202247191	1.29076712660792	0.375328774305124	0.692914660255614
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	4/649	89/18639	0.0449438202247191	1.29076712660792	0.375328774305124	0.692914660255614
GO:0005507	copper ion binding	3/649	63/18639	0.0476190476190476	1.36759850319172	0.376552833260398	0.693692213085254
GO:0019210	kinase inhibitor activity	4/649	90/18639	0.0444444444444444	1.27642526964561	0.383270866102688	0.696979037702679
GO:0140793	histone H2AXY142 phosphatase activity	4/649	90/18639	0.0444444444444444	1.27642526964561	0.383270866102688	0.696979037702679
GO:0000146	microfilament motor activity	2/649	38/18639	0.0526315789473684	1.5115562403698	0.383463458765517	0.696979037702679
GO:0005109	frizzled binding	2/649	38/18639	0.0526315789473684	1.5115562403698	0.383463458765517	0.696979037702679
GO:0042162	telomeric DNA binding	2/649	38/18639	0.0526315789473684	1.5115562403698	0.383463458765517	0.696979037702679
GO:0004065	arylsulfatase activity	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.696979037702679
GO:0008494	translation activator activity	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.696979037702679
GO:0016530	metallochaperone activity	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.696979037702679
GO:0031404	chloride ion binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.696979037702679
GO:0034236	protein kinase A catalytic subunit binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.696979037702679
GO:0042043	neurexin family protein binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.696979037702679
GO:0061783	peptidoglycan muralytic activity	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.696979037702679
GO:0070742	C2H2 zinc finger domain binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.696979037702679
GO:0071933	Arp2/3 complex binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.696979037702679
GO:0098821	BMP receptor activity	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.696979037702679
GO:1901612	cardiolipin binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.696979037702679
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/649	39/18639	0.0512820512820513	1.47279838805263	0.395893235717756	0.703810196831567
GO:0043178	alcohol binding	4/649	92/18639	0.0434782608695652	1.24867689421853	0.39911657361617	0.706632622140104
GO:0052689	carboxylic ester hydrolase activity	4/649	92/18639	0.0434782608695652	1.24867689421853	0.39911657361617	0.706632622140104
GO:0015144	carbohydrate transmembrane transporter activity	2/649	40/18639	0.05	1.43597842835131	0.408206364805644	0.712724849733748
GO:0000774	adenyl-nucleotide exchange factor activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.712724849733748
GO:0004559	alpha-mannosidase activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.712724849733748
GO:0004953	icosanoid receptor activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.712724849733748
GO:0005041	low-density lipoprotein particle receptor activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.712724849733748
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.712724849733748
GO:0015929	hexosaminidase activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.712724849733748
GO:0030553	cGMP binding	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.712724849733748
GO:0031005	filamin binding	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.712724849733748
GO:0045504	dynein heavy chain binding	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.712724849733748
GO:0051371	muscle alpha-actinin binding	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.712724849733748
GO:0120283	protein serine/threonine kinase binding	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.712724849733748
GO:0003697	single-stranded DNA binding	5/649	121/18639	0.0413223140495868	1.1867590316953	0.413565299282059	0.713158266139101
GO:0042054	histone methyltransferase activity	3/649	67/18639	0.0447761194029851	1.28595083135938	0.414358159261376	0.713158266139101
GO:0001727	lipid kinase activity	2/649	41/18639	0.0487804878048781	1.40095456424518	0.420395897652641	0.716675975908386
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	2/649	41/18639	0.0487804878048781	1.40095456424518	0.420395897652641	0.716675975908386
GO:0043021	ribonucleoprotein complex binding	7/649	177/18639	0.0395480225988701	1.13580214671855	0.42041674356079	0.716675975908386
GO:0005548	phospholipid transporter activity	3/649	68/18639	0.0441176470588235	1.26703978972174	0.423700810106047	0.716675975908386
GO:0005319	lipid transporter activity	7/649	178/18639	0.0393258426966292	1.12942123578193	0.426121695285549	0.716675975908386
GO:0043175	RNA polymerase core enzyme binding	2/649	42/18639	0.0476190476190476	1.36759850319172	0.432455509532405	0.716675975908386
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.716675975908386
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.716675975908386
GO:0005521	lamin binding	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.716675975908386
GO:0008142	oxysterol binding	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.716675975908386
GO:0015923	mannosidase activity	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.716675975908386
GO:0022858	alanine transmembrane transporter activity	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.716675975908386
GO:0030275	LRR domain binding	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.716675975908386
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.716675975908386
GO:0070411	I-SMAD binding	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.716675975908386
GO:0097027	ubiquitin-protein transferase activator activity	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.716675975908386
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.716675975908386
GO:0140327	flippase activity	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.716675975908386
GO:0140328	floppase activity	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.716675975908386
GO:0002039	p53 binding	3/649	69/18639	0.0434782608695652	1.24867689421853	0.43299173544465	0.716675975908386
GO:0004725	protein tyrosine phosphatase activity	4/649	98/18639	0.0408163265306122	1.17222728845005	0.446140602941353	0.733821204641661
GO:0140299	molecular sensor activity	3/649	71/18639	0.0422535211267606	1.21350289719829	0.45140344781104	0.733821204641661
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.733821204641661
GO:0004550	nucleoside diphosphate kinase activity	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.733821204641661
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.733821204641661
GO:0008484	sulfuric ester hydrolase activity	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.733821204641661
GO:0016018	cyclosporin A binding	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.733821204641661
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.733821204641661
GO:0070403	NAD+ binding	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.733821204641661
GO:0070492	oligosaccharide binding	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.733821204641661
GO:1990226	histone methyltransferase binding	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.733821204641661
GO:0019205	nucleobase-containing compound kinase activity	2/649	44/18639	0.0454545454545455	1.30543493486483	0.456162582067212	0.738060806940208
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	5/649	128/18639	0.0390625	1.12185814714946	0.461515872150202	0.743808263083389
GO:0004715	non-membrane spanning protein tyrosine kinase activity	2/649	45/18639	0.0444444444444444	1.27642526964561	0.467800205780103	0.743808263083389
GO:0051539	4 iron, 4 sulfur cluster binding	2/649	45/18639	0.0444444444444444	1.27642526964561	0.467800205780103	0.743808263083389
GO:0140303	intramembrane lipid transporter activity	2/649	45/18639	0.0444444444444444	1.27642526964561	0.467800205780103	0.743808263083389
GO:0043539	protein serine/threonine kinase activator activity	3/649	73/18639	0.0410958904109589	1.18025624248053	0.469565232848669	0.743808263083389
GO:0000900	mRNA regulatory element binding translation repressor activity	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.743808263083389
GO:0008409	5'-3' exonuclease activity	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.743808263083389
GO:0008525	phosphatidylcholine transporter activity	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.743808263083389
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.743808263083389
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.743808263083389
GO:0017128	phospholipid scramblase activity	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.743808263083389
GO:0030228	lipoprotein particle receptor activity	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.743808263083389
GO:0050811	GABA receptor binding	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.743808263083389
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.743808263083389
GO:0015631	tubulin binding	14/649	385/18639	0.0363636363636364	1.04434794789186	0.472652736251966	0.743846929183422
GO:0016298	lipase activity	5/649	130/18639	0.0384615384615385	1.10459879103947	0.475018490623432	0.746210865270264
GO:0008234	cysteine-type peptidase activity	7/649	187/18639	0.0374331550802139	1.07506406400633	0.477052516265549	0.748046050913675
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/649	46/18639	0.0434782608695652	1.24867689421853	0.479288172908901	0.748833601072857
GO:0030291	protein serine/threonine kinase inhibitor activity	2/649	46/18639	0.0434782608695652	1.24867689421853	0.479288172908901	0.748833601072857
GO:0003756	protein disulfide isomerase activity	1/649	19/18639	0.0526315789473684	1.5115562403698	0.490177837911609	0.751592352871452
GO:0008301	DNA binding, bending	1/649	19/18639	0.0526315789473684	1.5115562403698	0.490177837911609	0.751592352871452
GO:0015245	fatty acid transmembrane transporter activity	1/649	19/18639	0.0526315789473684	1.5115562403698	0.490177837911609	0.751592352871452
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/649	19/18639	0.0526315789473684	1.5115562403698	0.490177837911609	0.751592352871452
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/649	19/18639	0.0526315789473684	1.5115562403698	0.490177837911609	0.751592352871452
GO:0046624	sphingolipid transporter activity	1/649	19/18639	0.0526315789473684	1.5115562403698	0.490177837911609	0.751592352871452
GO:0050145	nucleoside monophosphate kinase activity	1/649	19/18639	0.0526315789473684	1.5115562403698	0.490177837911609	0.751592352871452
GO:1990380	K48-linked deubiquitinase activity	1/649	19/18639	0.0526315789473684	1.5115562403698	0.490177837911609	0.751592352871452
GO:0001784	phosphotyrosine residue binding	2/649	47/18639	0.0425531914893617	1.22210930072452	0.490622785902198	0.751592352871452
GO:0043495	protein-membrane adaptor activity	2/649	47/18639	0.0425531914893617	1.22210930072452	0.490622785902198	0.751592352871452
GO:0140938	histone H3 methyltransferase activity	2/649	47/18639	0.0425531914893617	1.22210930072452	0.490622785902198	0.751592352871452
GO:0051540	metal cluster binding	3/649	77/18639	0.038961038961039	1.11894422988414	0.5050410897199	0.768593347199746
GO:0004497	monooxygenase activity	4/649	106/18639	0.0377358490566038	1.08375730441608	0.506896897054584	0.768593347199746
GO:0008013	beta-catenin binding	4/649	106/18639	0.0377358490566038	1.08375730441608	0.506896897054584	0.768593347199746
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/649	20/18639	0.05	1.43597842835131	0.507947686633166	0.768593347199746
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/649	20/18639	0.05	1.43597842835131	0.507947686633166	0.768593347199746
GO:0140664	ATP-dependent DNA damage sensor activity	1/649	20/18639	0.05	1.43597842835131	0.507947686633166	0.768593347199746
GO:0140939	histone H4 methyltransferase activity	1/649	20/18639	0.05	1.43597842835131	0.507947686633166	0.768593347199746
GO:0008236	serine-type peptidase activity	7/649	194/18639	0.0360824742268041	1.03627309262466	0.515828350750962	0.779153313022432
GO:0001846	opsonin binding	1/649	21/18639	0.0476190476190476	1.36759850319172	0.525099088500885	0.782216573215112
GO:0005123	death receptor binding	1/649	21/18639	0.0476190476190476	1.36759850319172	0.525099088500885	0.782216573215112
GO:0008373	sialyltransferase activity	1/649	21/18639	0.0476190476190476	1.36759850319172	0.525099088500885	0.782216573215112
GO:0036122	BMP binding	1/649	21/18639	0.0476190476190476	1.36759850319172	0.525099088500885	0.782216573215112
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/649	21/18639	0.0476190476190476	1.36759850319172	0.525099088500885	0.782216573215112
GO:0051010	microtubule plus-end binding	1/649	21/18639	0.0476190476190476	1.36759850319172	0.525099088500885	0.782216573215112
GO:0061891	calcium ion sensor activity	1/649	21/18639	0.0476190476190476	1.36759850319172	0.525099088500885	0.782216573215112
GO:0072542	protein phosphatase activator activity	1/649	21/18639	0.0476190476190476	1.36759850319172	0.525099088500885	0.782216573215112
GO:0016874	ligase activity	6/649	167/18639	0.0359281437125748	1.03184078683926	0.5271220224708	0.783878532555545
GO:0070851	growth factor receptor binding	5/649	139/18639	0.0359712230215827	1.03307800600814	0.534230026808976	0.787859687791671
GO:0030544	Hsp70 protein binding	2/649	51/18639	0.0392156862745098	1.12625759086377	0.534368536359893	0.787859687791671
GO:0017171	serine hydrolase activity	7/649	198/18639	0.0353535353535354	1.01533828267264	0.537522844481816	0.787859687791671
GO:0015101	organic cation transmembrane transporter activity	3/649	81/18639	0.037037037037037	1.06368772470467	0.539250262327669	0.787859687791671
GO:0008649	rRNA methyltransferase activity	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.787859687791671
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.787859687791671
GO:0033691	sialic acid binding	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.787859687791671
GO:0034062	5'-3' RNA polymerase activity	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.787859687791671
GO:0050321	tau-protein kinase activity	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.787859687791671
GO:0070034	telomerase RNA binding	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.787859687791671
GO:0097747	RNA polymerase activity	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.787859687791671
GO:0140517	protein-RNA adaptor activity	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.787859687791671
GO:0140784	metal ion sensor activity	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.787859687791671
GO:0001216	DNA-binding transcription activator activity	17/649	491/18639	0.0346232179226069	0.9943638811394	0.544761260118287	0.791048283600337
GO:0043022	ribosome binding	4/649	112/18639	0.0357142857142857	1.02569887739379	0.550435695136659	0.796353474578953
GO:0005544	calcium-dependent phospholipid binding	2/649	53/18639	0.0377358490566038	1.08375730441608	0.555254977359704	0.796353474578953
GO:0140296	general transcription initiation factor binding	2/649	53/18639	0.0377358490566038	1.08375730441608	0.555254977359704	0.796353474578953
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/649	23/18639	0.0434782608695652	1.24867689421853	0.557631773287345	0.796353474578953
GO:0005158	insulin receptor binding	1/649	23/18639	0.0434782608695652	1.24867689421853	0.557631773287345	0.796353474578953
GO:0005212	structural constituent of eye lens	1/649	23/18639	0.0434782608695652	1.24867689421853	0.557631773287345	0.796353474578953
GO:0008171	O-methyltransferase activity	1/649	23/18639	0.0434782608695652	1.24867689421853	0.557631773287345	0.796353474578953
GO:0016493	C-C chemokine receptor activity	1/649	23/18639	0.0434782608695652	1.24867689421853	0.557631773287345	0.796353474578953
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/649	23/18639	0.0434782608695652	1.24867689421853	0.557631773287345	0.796353474578953
GO:0140102	catalytic activity, acting on a rRNA	1/649	23/18639	0.0434782608695652	1.24867689421853	0.557631773287345	0.796353474578953
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	2/649	54/18639	0.037037037037037	1.06368772470467	0.565446252046256	0.801162633966677
GO:0051287	NAD binding	2/649	54/18639	0.037037037037037	1.06368772470467	0.565446252046256	0.801162633966677
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.801162633966677
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.801162633966677
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.801162633966677
GO:0004806	triacylglycerol lipase activity	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.801162633966677
GO:0005540	hyaluronic acid binding	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.801162633966677
GO:0015295	solute:proton symporter activity	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.801162633966677
GO:0019957	C-C chemokine binding	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.801162633966677
GO:0030215	semaphorin receptor binding	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.801162633966677
GO:0030552	cAMP binding	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.801162633966677
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.801162633966677
GO:0070840	dynein complex binding	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.801162633966677
GO:0004252	serine-type endopeptidase activity	6/649	176/18639	0.0340909090909091	0.97907620114862	0.57866633283569	0.807702280403936
GO:1990782	protein tyrosine kinase binding	4/649	117/18639	0.0341880341880342	0.981865592035084	0.585119889681924	0.814069429032659
GO:0004709	MAP kinase kinase kinase activity	1/649	25/18639	0.04	1.14878274268105	0.587939032079143	0.814069429032659
GO:0005251	delayed rectifier potassium channel activity	1/649	25/18639	0.04	1.14878274268105	0.587939032079143	0.814069429032659
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/649	25/18639	0.04	1.14878274268105	0.587939032079143	0.814069429032659
GO:0019211	phosphatase activator activity	1/649	25/18639	0.04	1.14878274268105	0.587939032079143	0.814069429032659
GO:0016887	ATP hydrolysis activity	14/649	417/18639	0.0335731414868106	0.964206138940927	0.593940187934529	0.815662104076175
GO:0001637	G protein-coupled chemoattractant receptor activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.815662104076175
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.815662104076175
GO:0004529	DNA exonuclease activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.815662104076175
GO:0004950	chemokine receptor activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.815662104076175
GO:0005112	Notch binding	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.815662104076175
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.815662104076175
GO:0008157	protein phosphatase 1 binding	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.815662104076175
GO:0008198	ferrous iron binding	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.815662104076175
GO:0052742	phosphatidylinositol kinase activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.815662104076175
GO:0070006	metalloaminopeptidase activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.815662104076175
GO:0070412	R-SMAD binding	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.815662104076175
GO:0097602	cullin family protein binding	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.815662104076175
GO:0120014	phospholipid transfer activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.815662104076175
GO:0070063	RNA polymerase binding	2/649	59/18639	0.0338983050847458	0.973544697187329	0.613856489735767	0.826666718613182
GO:0070888	E-box binding	2/649	59/18639	0.0338983050847458	0.973544697187329	0.613856489735767	0.826666718613182
GO:0008266	poly(U) RNA binding	1/649	27/18639	0.037037037037037	1.06368772470467	0.616172878225566	0.826666718613182
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/649	27/18639	0.037037037037037	1.06368772470467	0.616172878225566	0.826666718613182
GO:0035255	ionotropic glutamate receptor binding	1/649	27/18639	0.037037037037037	1.06368772470467	0.616172878225566	0.826666718613182
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	1/649	27/18639	0.037037037037037	1.06368772470467	0.616172878225566	0.826666718613182
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	3/649	91/18639	0.032967032967033	0.946798963748116	0.618469890926605	0.82842502130623
GO:0003774	cytoskeletal motor activity	5/649	153/18639	0.0326797385620915	0.938547992386477	0.619683681063204	0.82842502130623
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	16/649	484/18639	0.0330578512396694	0.949407225356238	0.620359940723531	0.82842502130623
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	2/649	60/18639	0.0333333333333333	0.957318952234206	0.623028419693018	0.830704559590691
GO:0008017	microtubule binding	9/649	276/18639	0.0326086956521739	0.936507670663898	0.626533493052395	0.83170822576018
GO:0005242	inward rectifier potassium channel activity	1/649	28/18639	0.0357142857142857	1.02569887739379	0.629556920887914	0.83170822576018
GO:0046875	ephrin receptor binding	1/649	28/18639	0.0357142857142857	1.02569887739379	0.629556920887914	0.83170822576018
GO:0051019	mitogen-activated protein kinase binding	1/649	28/18639	0.0357142857142857	1.02569887739379	0.629556920887914	0.83170822576018
GO:0051393	alpha-actinin binding	1/649	28/18639	0.0357142857142857	1.02569887739379	0.629556920887914	0.83170822576018
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	1/649	28/18639	0.0357142857142857	1.02569887739379	0.629556920887914	0.83170822576018
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	2/649	61/18639	0.0327868852459016	0.941625198918892	0.632030986724326	0.833701942793615
GO:0001217	DNA-binding transcription repressor activity	9/649	278/18639	0.0323741007194245	0.929770205407323	0.635071678020303	0.836435868612107
GO:0016410	N-acyltransferase activity	3/649	94/18639	0.0319148936170213	0.916581975543389	0.640354436167164	0.837252431829653
GO:0003785	actin monomer binding	1/649	29/18639	0.0344827586206897	0.99032995058711	0.642474956369282	0.837252431829653
GO:0004181	metallocarboxypeptidase activity	1/649	29/18639	0.0344827586206897	0.99032995058711	0.642474956369282	0.837252431829653
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/649	29/18639	0.0344827586206897	0.99032995058711	0.642474956369282	0.837252431829653
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/649	29/18639	0.0344827586206897	0.99032995058711	0.642474956369282	0.837252431829653
GO:0097472	cyclin-dependent protein kinase activity	1/649	29/18639	0.0344827586206897	0.99032995058711	0.642474956369282	0.837252431829653
GO:0106222	lncRNA binding	1/649	29/18639	0.0344827586206897	0.99032995058711	0.642474956369282	0.837252431829653
GO:0008276	protein methyltransferase activity	3/649	95/18639	0.0315789473684211	0.90693374422188	0.647450388372655	0.842465565593334
GO:0008187	poly-pyrimidine tract binding	1/649	30/18639	0.0333333333333333	0.957318952234206	0.654943185994018	0.84711214475873
GO:0031624	ubiquitin conjugating enzyme binding	1/649	30/18639	0.0333333333333333	0.957318952234206	0.654943185994018	0.84711214475873
GO:0033612	receptor serine/threonine kinase binding	1/649	30/18639	0.0333333333333333	0.957318952234206	0.654943185994018	0.84711214475873
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/649	30/18639	0.0333333333333333	0.957318952234206	0.654943185994018	0.84711214475873
GO:0035091	phosphatidylinositol binding	9/649	284/18639	0.0316901408450704	0.910127172898717	0.660038061081254	0.85242583673274
GO:0008327	methyl-CpG binding	1/649	31/18639	0.032258064516129	0.926437695710522	0.666977248667449	0.853951856366777
GO:0016411	acylglycerol O-acyltransferase activity	1/649	31/18639	0.032258064516129	0.926437695710522	0.666977248667449	0.853951856366777
GO:0017147	Wnt-protein binding	1/649	31/18639	0.032258064516129	0.926437695710522	0.666977248667449	0.853951856366777
GO:0047499	calcium-independent phospholipase A2 activity	1/649	31/18639	0.032258064516129	0.926437695710522	0.666977248667449	0.853951856366777
GO:0016798	hydrolase activity, acting on glycosyl bonds	4/649	130/18639	0.0307692307692308	0.883679032831575	0.667572952616815	0.853951856366777
GO:0005249	voltage-gated potassium channel activity	3/649	98/18639	0.0306122448979592	0.879170466337536	0.668138257990672	0.853951856366777
GO:0008170	N-methyltransferase activity	3/649	98/18639	0.0306122448979592	0.879170466337536	0.668138257990672	0.853951856366777
GO:0008235	metalloexopeptidase activity	2/649	66/18639	0.0303030303030303	0.870289956576551	0.674531663763693	0.860849863355733
GO:0042910	xenobiotic transmembrane transporter activity	1/649	32/18639	0.03125	0.897486517719569	0.678592240370739	0.862211317176939
GO:0047498	calcium-dependent phospholipase A2 activity	1/649	32/18639	0.03125	0.897486517719569	0.678592240370739	0.862211317176939
GO:0051059	NF-kappaB binding	1/649	32/18639	0.03125	0.897486517719569	0.678592240370739	0.862211317176939
GO:0140416	transcription regulator inhibitor activity	1/649	33/18639	0.0303030303030303	0.870289956576551	0.689802732981014	0.875168225103666
GO:0141003	histone H2AX kinase activity	11/649	354/18639	0.0310734463276836	0.892415972421718	0.692297260680774	0.877045210012007
GO:0005085	guanyl-nucleotide exchange factor activity	7/649	230/18639	0.0304347826086957	0.874073825952971	0.693517876918027	0.87730519129894
GO:0016279	protein-lysine N-methyltransferase activity	2/649	69/18639	0.0289855072463768	0.832451262812353	0.69806377074117	0.879821686583653
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/649	34/18639	0.0294117647058824	0.844693193147829	0.700622792440077	0.879821686583653
GO:0030332	cyclin binding	1/649	34/18639	0.0294117647058824	0.844693193147829	0.700622792440077	0.879821686583653
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/649	34/18639	0.0294117647058824	0.844693193147829	0.700622792440077	0.879821686583653
GO:0090482	vitamin transmembrane transporter activity	1/649	34/18639	0.0294117647058824	0.844693193147829	0.700622792440077	0.879821686583653
GO:0140789	histone phosphatase activity	4/649	136/18639	0.0294117647058824	0.844693193147829	0.701617062564974	0.879821686583653
GO:0140996	histone H3 kinase activity	11/649	357/18639	0.030812324929972	0.884916678535821	0.702699391270897	0.87990184646095
GO:0008028	monocarboxylic acid transmembrane transporter activity	2/649	70/18639	0.0285714285714286	0.820559101915034	0.705588377299217	0.880965835240641
GO:0016278	lysine N-methyltransferase activity	2/649	70/18639	0.0285714285714286	0.820559101915034	0.705588377299217	0.880965835240641
GO:0004623	phospholipase A2 activity	1/649	35/18639	0.0285714285714286	0.820559101915034	0.711065996294224	0.885246427663126
GO:0061631	ubiquitin conjugating enzyme activity	1/649	35/18639	0.0285714285714286	0.820559101915034	0.711065996294224	0.885246427663126
GO:0035173	histone kinase activity	11/649	360/18639	0.0305555555555556	0.877542372881356	0.712882009659752	0.886230296900756
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	8/649	268/18639	0.0298507462686567	0.857300554239588	0.719789113568286	0.892649956076846
GO:0004190	aspartic-type endopeptidase activity	1/649	36/18639	0.0277777777777778	0.797765793528505	0.721145450626897	0.892649956076846
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/649	36/18639	0.0277777777777778	0.797765793528505	0.721145450626897	0.892649956076846
GO:0042578	phosphoric ester hydrolase activity	11/649	363/18639	0.0303030303030303	0.870289956576551	0.722842392851244	0.893470425498533
GO:0004521	RNA endonuclease activity	2/649	73/18639	0.0273972602739726	0.786837494987019	0.727227844199904	0.896981489679067
GO:0030280	structural constituent of skin epidermis	1/649	37/18639	0.027027027027027	0.776204555865573	0.730873806405166	0.896981489679067
GO:0030551	cyclic nucleotide binding	1/649	37/18639	0.027027027027027	0.776204555865573	0.730873806405166	0.896981489679067
GO:0042805	actinin binding	1/649	37/18639	0.027027027027027	0.776204555865573	0.730873806405166	0.896981489679067
GO:0070001	aspartic-type peptidase activity	1/649	37/18639	0.027027027027027	0.776204555865573	0.730873806405166	0.896981489679067
GO:0004721	phosphoprotein phosphatase activity	5/649	175/18639	0.0285714285714286	0.820559101915034	0.733333302421155	0.897161611617028
GO:0003684	damaged DNA binding	2/649	74/18639	0.027027027027027	0.776204555865573	0.734135716913471	0.897161611617028
GO:0048029	monosaccharide binding	2/649	74/18639	0.027027027027027	0.776204555865573	0.734135716913471	0.897161611617028
GO:0140097	catalytic activity, acting on DNA	10/649	336/18639	0.0297619047619048	0.854749064494827	0.737152914552245	0.89906259702646
GO:0005501	retinoid binding	1/649	38/18639	0.0263157894736842	0.7557781201849	0.740263275260291	0.89906259702646
GO:0019840	isoprenoid binding	1/649	38/18639	0.0263157894736842	0.7557781201849	0.740263275260291	0.89906259702646
GO:0043531	ADP binding	1/649	38/18639	0.0263157894736842	0.7557781201849	0.740263275260291	0.89906259702646
GO:0019003	GDP binding	2/649	75/18639	0.0266666666666667	0.765855161787365	0.740894177179212	0.89906259702646
GO:1902936	phosphatidylinositol bisphosphate binding	3/649	111/18639	0.027027027027027	0.776204555865573	0.747461996206832	0.903687746364238
GO:0051536	iron-sulfur cluster binding	2/649	76/18639	0.0263157894736842	0.7557781201849	0.747505236322743	0.903687746364238
GO:0008194	UDP-glycosyltransferase activity	4/649	145/18639	0.0275862068965517	0.792263960469688	0.747843447512072	0.903687746364238
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/649	39/18639	0.0256410256410256	0.736399194026313	0.749325644721937	0.904214185809712
GO:0005261	monoatomic cation channel activity	10/649	341/18639	0.0293255131964809	0.842216087009566	0.753351812857046	0.90591211768621
GO:0004177	aminopeptidase activity	1/649	40/18639	0.025	0.717989214175655	0.758072292924919	0.90591211768621
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/649	40/18639	0.025	0.717989214175655	0.758072292924919	0.90591211768621
GO:0030331	nuclear estrogen receptor binding	1/649	40/18639	0.025	0.717989214175655	0.758072292924919	0.90591211768621
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	1/649	40/18639	0.025	0.717989214175655	0.758072292924919	0.90591211768621
GO:0061791	GTPase motor activity	1/649	40/18639	0.025	0.717989214175655	0.758072292924919	0.90591211768621
GO:1990606	membrane scission GTPase motor activity	1/649	40/18639	0.025	0.717989214175655	0.758072292924919	0.90591211768621
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	5/649	181/18639	0.0276243093922652	0.793358247707906	0.759626772023172	0.906515926834282
GO:0001530	lipopolysaccharide binding	1/649	41/18639	0.024390243902439	0.70047728212259	0.766514202806726	0.90970916377062
GO:0015175	neutral L-amino acid transmembrane transporter activity	1/649	41/18639	0.024390243902439	0.70047728212259	0.766514202806726	0.90970916377062
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/649	41/18639	0.024390243902439	0.70047728212259	0.766514202806726	0.90970916377062
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/649	41/18639	0.024390243902439	0.70047728212259	0.766514202806726	0.90970916377062
GO:0000049	tRNA binding	2/649	80/18639	0.025	0.717989214175655	0.772517022169012	0.915575729978088
GO:0019894	kinesin binding	1/649	42/18639	0.0238095238095238	0.683799251595862	0.774661975813417	0.916860201510674
GO:1901981	phosphatidylinositol phosphate binding	5/649	185/18639	0.027027027027027	0.776204555865573	0.77604412585262	0.917239568723206
GO:0030971	receptor tyrosine kinase binding	2/649	81/18639	0.0246913580246914	0.709125149803116	0.778422509759932	0.918793782011723
GO:0005506	iron ion binding	4/649	154/18639	0.025974025974026	0.745962819922758	0.788390872396885	0.927527112537599
GO:0005254	chloride channel activity	2/649	83/18639	0.0240963855421687	0.692037796795812	0.789831758316588	0.927527112537599
GO:0001046	core promoter sequence-specific DNA binding	1/649	44/18639	0.0227272727272727	0.652717467432414	0.790115688457955	0.927527112537599
GO:0043014	alpha-tubulin binding	1/649	44/18639	0.0227272727272727	0.652717467432414	0.790115688457955	0.927527112537599
GO:0004527	exonuclease activity	2/649	84/18639	0.0238095238095238	0.683799251595862	0.795339928130661	0.932393077211522
GO:0008528	G protein-coupled peptide receptor activity	3/649	122/18639	0.0245901639344262	0.706218899189169	0.802083490140092	0.939024573822547
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/649	46/18639	0.0217391304347826	0.624338447109265	0.804511104057621	0.940592143309587
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	2/649	86/18639	0.0232558139534884	0.667896943419214	0.80597443814638	0.940930517261522
GO:0030695	GTPase regulator activity	14/649	489/18639	0.0286298568507157	0.822237136888276	0.809027777045094	0.940930517261522
GO:0005267	potassium channel activity	3/649	124/18639	0.0241935483870968	0.694828271782892	0.810872784673494	0.940930517261522
GO:0060589	nucleoside-triphosphatase regulator activity	14/649	490/18639	0.0285714285714286	0.820559101915034	0.811305415723301	0.940930517261522
GO:0061733	protein-lysine-acetyltransferase activity	1/649	47/18639	0.0212765957446809	0.611054650362259	0.811334763147956	0.940930517261522
GO:0140359	ABC-type transporter activity	1/649	47/18639	0.0212765957446809	0.611054650362259	0.811334763147956	0.940930517261522
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/649	48/18639	0.0208333333333333	0.598324345146379	0.817920592467931	0.944763892904135
GO:0032266	phosphatidylinositol-3-phosphate binding	1/649	48/18639	0.0208333333333333	0.598324345146379	0.817920592467931	0.944763892904135
GO:0038187	pattern recognition receptor activity	1/649	48/18639	0.0208333333333333	0.598324345146379	0.817920592467931	0.944763892904135
GO:0003727	single-stranded RNA binding	2/649	89/18639	0.0224719101123595	0.645383563303959	0.821004929067779	0.947060425520108
GO:0016763	pentosyltransferase activity	1/649	49/18639	0.0204081632653061	0.586113644225024	0.824276868918274	0.948302549594392
GO:0060590	ATPase regulator activity	1/649	49/18639	0.0204081632653061	0.586113644225024	0.824276868918274	0.948302549594392
GO:0001653	peptide receptor activity	3/649	128/18639	0.0234375	0.673114888289676	0.827463637550264	0.950117189217252
GO:0004674	protein serine/threonine kinase activity	12/649	433/18639	0.0277136258660508	0.795923378300957	0.82805352254698	0.950117189217252
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	3/649	130/18639	0.0230769230769231	0.662759274623681	0.835281828999633	0.955077389482507
GO:0005272	sodium channel activity	1/649	51/18639	0.0196078431372549	0.563128795431886	0.836332442686896	0.955077389482507
GO:0016597	amino acid binding	1/649	51/18639	0.0196078431372549	0.563128795431886	0.836332442686896	0.955077389482507
GO:0005096	GTPase activator activity	7/649	271/18639	0.025830258302583	0.741833874425031	0.836798129442428	0.955077389482507
GO:0005246	calcium channel regulator activity	1/649	53/18639	0.0188679245283019	0.541878652208041	0.84756212446505	0.964813801762586
GO:0034212	protein N-acetyltransferase activity	1/649	53/18639	0.0188679245283019	0.541878652208041	0.84756212446505	0.964813801762586
GO:0015297	antiporter activity	3/649	135/18639	0.0222222222222222	0.638212634822804	0.85350355425138	0.970298777464727
GO:0008374	O-acyltransferase activity	1/649	55/18639	0.0181818181818182	0.522173973945931	0.858022412374735	0.973858839010483
GO:0005216	monoatomic ion channel activity	12/649	448/18639	0.0267857142857143	0.769274158045344	0.859488854873283	0.973858839010483
GO:0042626	ATPase-coupled transmembrane transporter activity	2/649	98/18639	0.0204081632653061	0.586113644225024	0.860016544172452	0.973858839010483
GO:0030170	pyridoxal phosphate binding	1/649	56/18639	0.0178571428571429	0.512849438696896	0.862980626664919	0.974660472468615
GO:0170055	lipid transmembrane transporter activity	1/649	56/18639	0.0178571428571429	0.512849438696896	0.862980626664919	0.974660472468615
GO:0043130	ubiquitin binding	2/649	100/18639	0.02	0.574391371340524	0.867557294796175	0.977509487098187
GO:0070279	vitamin B6 binding	1/649	57/18639	0.0175438596491228	0.503852080123267	0.867765945143877	0.977509487098187
GO:0004879	nuclear receptor activity	1/649	59/18639	0.0169491525423729	0.486772348593664	0.876841765361894	0.979205428649629
GO:0005253	monoatomic anion channel activity	2/649	103/18639	0.0194174757281553	0.557661525573324	0.878171152313048	0.979205428649629
GO:0022843	voltage-gated monoatomic cation channel activity	3/649	143/18639	0.020979020979021	0.602508431476074	0.879004366001085	0.979205428649629
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/649	60/18639	0.0166666666666667	0.478659476117103	0.881143686474926	0.979205428649629
GO:0098531	ligand-modulated transcription factor activity	1/649	60/18639	0.0166666666666667	0.478659476117103	0.881143686474926	0.979205428649629
GO:0015179	L-amino acid transmembrane transporter activity	1/649	62/18639	0.0161290322580645	0.463218847855261	0.889302625760187	0.979205428649629
GO:0015085	calcium ion transmembrane transporter activity	3/649	147/18639	0.0204081632653061	0.586113644225024	0.890213618383343	0.979205428649629
GO:0019888	protein phosphatase regulator activity	2/649	107/18639	0.0186915887850467	0.536814365738807	0.891103527447522	0.979205428649629
GO:0019001	guanyl nucleotide binding	10/649	400/18639	0.025	0.717989214175655	0.893888710007828	0.979205428649629
GO:0032561	guanyl ribonucleotide binding	10/649	400/18639	0.025	0.717989214175655	0.893888710007828	0.979205428649629
GO:0003924	GTPase activity	8/649	331/18639	0.0241691842900302	0.694128545426615	0.893920339300631	0.979205428649629
GO:0046943	carboxylic acid transmembrane transporter activity	4/649	188/18639	0.0212765957446809	0.611054650362259	0.896636600412362	0.979205428649629
GO:0004536	DNA nuclease activity	1/649	64/18639	0.015625	0.448743258859784	0.896902294958531	0.979205428649629
GO:0003730	mRNA 3'-UTR binding	6/649	262/18639	0.0229007633587786	0.657700043519684	0.897361523355882	0.979205428649629
GO:0019842	vitamin binding	3/649	150/18639	0.02	0.574391371340524	0.898001211848862	0.979205428649629
GO:0005342	organic acid transmembrane transporter activity	4/649	189/18639	0.0211640211640212	0.607821556974099	0.898907908694146	0.979205428649629
GO:0000287	magnesium ion binding	5/649	230/18639	0.0217391304347826	0.624338447109265	0.906243822408734	0.979205428649629
GO:0016757	glycosyltransferase activity	6/649	267/18639	0.0224719101123595	0.645383563303959	0.906786874397128	0.979205428649629
GO:0008173	RNA methyltransferase activity	1/649	67/18639	0.0149253731343284	0.428650277119794	0.907336186922796	0.979205428649629
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/649	67/18639	0.0149253731343284	0.428650277119794	0.907336186922796	0.979205428649629
GO:0003777	microtubule motor activity	1/649	68/18639	0.0147058823529412	0.422346596573915	0.910574331155356	0.979205428649629
GO:0140223	general transcription initiation factor activity	1/649	68/18639	0.0147058823529412	0.422346596573915	0.910574331155356	0.979205428649629
GO:0101005	deubiquitinase activity	2/649	115/18639	0.0173913043478261	0.499470757687412	0.913229155960955	0.979205428649629
GO:0005525	GTP binding	9/649	378/18639	0.0238095238095238	0.683799251595862	0.913512086216532	0.979205428649629
GO:0008080	N-acetyltransferase activity	1/649	69/18639	0.0144927536231884	0.416225631406177	0.913699486455564	0.979205428649629
GO:0016758	hexosyltransferase activity	4/649	197/18639	0.0203045685279188	0.583138448061446	0.915547920048477	0.979205428649629
GO:0015294	solute:monoatomic cation symporter activity	2/649	116/18639	0.0172413793103448	0.495164975293555	0.915678011786623	0.979205428649629
GO:0016791	phosphatase activity	6/649	273/18639	0.021978021978022	0.631199309165411	0.917103655755665	0.979205428649629
GO:0019208	phosphatase regulator activity	2/649	117/18639	0.0170940170940171	0.490932796017542	0.918061880782301	0.979205428649629
GO:0015079	potassium ion transmembrane transporter activity	3/649	160/18639	0.01875	0.538491910631741	0.920493628627937	0.979205428649629
GO:0032182	ubiquitin-like protein binding	2/649	120/18639	0.0166666666666667	0.478659476117103	0.9248388990475	0.979205428649629
GO:0004540	RNA nuclease activity	2/649	121/18639	0.0165289256198347	0.474703612678119	0.926978009607522	0.979205428649629
GO:0015108	chloride transmembrane transporter activity	2/649	121/18639	0.0165289256198347	0.474703612678119	0.926978009607522	0.979205428649629
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	5/649	243/18639	0.0205761316872428	0.59093762483593	0.928703798579501	0.979205428649629
GO:0004676	3-phosphoinositide-dependent protein kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0004711	ribosomal protein S6 kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0035175	histone H3S10 kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0035979	histone H2AXS139 kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0044022	histone H3S28 kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0044023	histone H4S1 kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0044024	histone H2AS1 kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0044025	histone H2BS14 kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0072354	histone H3T3 kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0072371	histone H2AS121 kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0072518	Rho-dependent protein serine/threonine kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0140823	histone H2BS36 kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0140855	histone H3S57 kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0140995	histone H2A kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0140997	histone H4 kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0140998	histone H2B kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:1990244	histone H2AT120 kinase activity	5/649	245/18639	0.0204081632653061	0.586113644225024	0.9316983426808	0.979205428649629
GO:0004677	DNA-dependent protein kinase activity	5/649	246/18639	0.0203252032520325	0.583731068435492	0.93315314144311	0.979205428649629
GO:0140857	histone H3T45 kinase activity	5/649	246/18639	0.0203252032520325	0.583731068435492	0.93315314144311	0.979205428649629
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	3/649	167/18639	0.0179640718562874	0.515920393419632	0.933438285223966	0.979205428649629
GO:0035402	histone H3T11 kinase activity	5/649	247/18639	0.0202429149797571	0.581367784757615	0.934580207191516	0.979205428649629
GO:0035403	histone H3T6 kinase activity	5/649	247/18639	0.0202429149797571	0.581367784757615	0.934580207191516	0.979205428649629
GO:0004518	nuclease activity	4/649	209/18639	0.0191387559808612	0.549656814679927	0.935941853421138	0.979205428649629
GO:0004679	AMP-activated protein kinase activity	5/649	248/18639	0.0201612903225806	0.579023559819076	0.935979972171856	0.979205428649629
GO:0004519	endonuclease activity	2/649	127/18639	0.015748031496063	0.452276670346869	0.938652643259372	0.979205428649629
GO:0019783	ubiquitin-like protein peptidase activity	2/649	127/18639	0.015748031496063	0.452276670346869	0.938652643259372	0.979205428649629
GO:0015370	solute:sodium symporter activity	1/649	79/18639	0.0126582278481013	0.363538842620585	0.939538542072387	0.979205428649629
GO:0016835	carbon-oxygen lyase activity	1/649	79/18639	0.0126582278481013	0.363538842620585	0.939538542072387	0.979205428649629
GO:0005244	voltage-gated monoatomic ion channel activity	3/649	173/18639	0.0173410404624277	0.498027200584269	0.942958153832123	0.981585355314402
GO:0005262	calcium channel activity	2/649	131/18639	0.0152671755725191	0.438466695679789	0.945427441316602	0.982218573871016
GO:0022832	voltage-gated channel activity	3/649	175/18639	0.0171428571428571	0.49233546114902	0.945840108172089	0.982218573871016
GO:0030165	PDZ domain binding	1/649	83/18639	0.0120481927710843	0.346018898397906	0.947562621078836	0.98282605595692
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4/649	229/18639	0.0174672489082969	0.501651852699147	0.960229425105693	0.994770051908056
GO:0140098	catalytic activity, acting on RNA	8/649	387/18639	0.020671834625323	0.59368617192819	0.9619463059925	0.995355219613796
GO:0061630	ubiquitin protein ligase activity	7/649	353/18639	0.0198300283286119	0.569509858269641	0.964739216458024	0.996141168830896
GO:0015293	symporter activity	2/649	146/18639	0.0136986301369863	0.393418747493509	0.965011757304931	0.996141168830896
GO:0016407	acetyltransferase activity	1/649	96/18639	0.0104166666666667	0.299162172573189	0.966995368447337	0.996864254440614
GO:0008509	monoatomic anion transmembrane transporter activity	2/649	149/18639	0.0134228187919463	0.38549756465807	0.968019802633883	0.996864254440614
GO:0015171	amino acid transmembrane transporter activity	1/649	102/18639	0.00980392156862745	0.281564397715943	0.973348187294825	0.999255196350158
GO:0015291	secondary active transmembrane transporter activity	5/649	287/18639	0.0174216027874564	0.50034091580185	0.973422495865027	0.999255196350158
GO:0004722	protein serine/threonine phosphatase activity	1/649	103/18639	0.00970873786407767	0.278830762786662	0.974281295480921	0.999255196350158
GO:0008168	methyltransferase activity	3/649	204/18639	0.0147058823529412	0.422346596573915	0.974967743661092	0.999255196350158
GO:0061659	ubiquitin-like protein ligase activity	7/649	372/18639	0.0188172043010753	0.540421989164471	0.976280275648168	0.999414879336513
GO:0004843	cysteine-type deubiquitinase activity	1/649	108/18639	0.00925925925925926	0.265921931176168	0.978479715055159	0.999898322052756
GO:0015081	sodium ion transmembrane transporter activity	2/649	164/18639	0.0121951219512195	0.350238641061295	0.979687463455674	0.999898322052756
GO:0015103	inorganic anion transmembrane transporter activity	2/649	165/18639	0.0121212121212121	0.348115982630621	0.980297704520285	0.999898322052756
GO:0016741	transferase activity, transferring one-carbon groups	3/649	215/18639	0.013953488372093	0.400738166051528	0.981483053803163	0.999898322052756
GO:0008514	organic anion transmembrane transporter activity	4/649	269/18639	0.0148698884758364	0.427056781665817	0.985432134398779	0.999898322052756
GO:0045182	translation regulator activity	6/649	356/18639	0.0168539325842697	0.48403767247797	0.986105566481623	0.999898322052756
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	1/649	122/18639	0.00819672131147541	0.235406299729723	0.986937934435372	0.999898322052756
GO:0106310	protein serine kinase activity	6/649	361/18639	0.0166204986149584	0.477333549590463	0.987626716454638	0.999898322052756
GO:0016779	nucleotidyltransferase activity	1/649	136/18639	0.00735294117647059	0.211173298286957	0.992074827198561	0.999898322052756
GO:0099094	ligand-gated monoatomic cation channel activity	1/649	136/18639	0.00735294117647059	0.211173298286957	0.992074827198561	0.999898322052756
GO:0140767	enzyme-substrate adaptor activity	1/649	139/18639	0.00719424460431655	0.206615601201627	0.992879896193712	0.999898322052756
GO:0016829	lyase activity	2/649	200/18639	0.01	0.287195685670262	0.993336220644409	0.999898322052756
GO:0004842	ubiquitin-protein transferase activity	7/649	449/18639	0.0155902004454343	0.447743830666333	0.995797665824196	0.999898322052756
GO:0046873	metal ion transmembrane transporter activity	7/649	450/18639	0.0155555555555556	0.446748844375963	0.995895796516941	0.999898322052756
GO:0019787	ubiquitin-like protein transferase activity	7/649	479/18639	0.0146137787056367	0.419701419559882	0.997954729680563	0.999898322052756
GO:0016755	aminoacyltransferase activity	7/649	496/18639	0.0141129032258065	0.405316491873354	0.99865329964048	0.999898322052756
GO:0015276	ligand-gated monoatomic ion channel activity	1/649	186/18639	0.00537634408602151	0.15440628261842	0.998673733658621	0.999898322052756
GO:0022834	ligand-gated channel activity	1/649	188/18639	0.00531914893617021	0.152763662590565	0.99876538628306	0.999898322052756
GO:0022836	gated channel activity	3/649	318/18639	0.00943396226415094	0.270939326104021	0.999069597019505	0.999898322052756
GO:0030371	translation repressor activity	2/649	329/18639	0.0060790273556231	0.174587042960646	0.999898322052756	0.999898322052756