category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	36/241	238/9376	5.88472401408696	RPL13A/C1QB/RPS26/C1QA/RPS11/RPS20/RPL8/RPS8/CFD/RPL28/RPLP0/RPS28/RPL23/C1QC/RPL37A/RPL18A/RPL7/RPS16/RPL10/EGFR/RPS2/CCL2/RPS9/RPS14/UBA52/C1R/RPS15/RPL13/C1S/RPS5/RPLP2/RPL27A/FCGR2A/NFKBIB/RPL36/IL1B	12.3977483423366
Genetic Information Processing	Translation	hsa03010	Ribosome	26/241	222/9376	4.55639041531158	RPL13A/RPS26/RPS11/RPS20/RPL8/RPS8/RPL28/RPLP0/RPS28/RPL23/RPL37A/RPL18A/RPL7/RPS16/RPL10/RPS2/RPS9/RPS14/UBA52/RPS15/RPL13/RPS5/RPLP2/MRPS34/RPL27A/RPL36	8.71004398065667
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	15/241	88/9376	6.63145982648057	SERPINE2/C1QB/C1QA/SERPINE1/CFD/CD59/SERPING1/C1QC/CLU/TFPI/C1R/A2M/C1S/F2R/VSIG4	8.62067170861878
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	24/241	275/9376	3.39530743115805	MT-CO2/MT-CO3/MT-CYB/MT-ND3/C1QB/C1QA/MT-ND1/MT-ND4/MT-ND2/MT-ATP6/MT-CO1/MT-ND5/COX7A1/C1QC/CAV1/NDUFA13/NDUFC1/NDUFA2/PSMD14/ATP5MC1/IL1B/PSMC5/LAMC1/PSMC1	6.54821507363692
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	19/241	205/9376	3.6057888877644	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND1/MT-ND4/MT-ND2/MT-ATP6/MT-CO1/GAPDH/MT-ND5/COX7A1/MMP2/NDUFA13/NDUFC1/NDUFA2/ATP5MC1/CTSD/INSR	6.12699738780662
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	13/241	99/9376	5.10868016262207	HLA-DRA/C1QB/C1QA/KRT18/KRT19/CFD/C1QC/HLA-DRB5/C1R/C1S/ITGAL/FCGR2A/HLA-DRB1	6.6750732807719
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	15/241	138/9376	4.22875699079921	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND1/MT-ND4/MT-ND2/MT-ATP6/MT-CO1/MT-ND5/COX7A1/NDUFA13/NDUFC1/NDUFA2/ATP5MC1	6.20620057752033
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	21/241	268/9376	3.04849197993435	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND1/MT-ND4/MT-ND2/MT-ATP6/MT-CO1/MT-ND5/COX7A1/NDUFA13/UBA52/NDUFC1/MAOA/UBE2G2/NDUFA2/PSMD14/ATP5MC1/PSMC5/PSMC1	5.52624376180207
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	22/241	308/9376	2.77889745109662	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND1/MT-ND4/TGM2/MT-ND2/MT-ATP6/MT-CO1/MT-ND5/COX7A1/NDUFA13/CREBBP/NDUFC1/GPX3/NDUFA2/PSMD14/ATP5MC1/PSMC5/ACTR1A/PSMC1	5.15597020484653
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	24/241	388/9376	2.40646789579501	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND1/MT-ND4/APOE/MT-ND2/MT-ATP6/MT-CO1/GAPDH/DKK1/MT-ND5/COX7A1/NDUFA13/NDUFC1/WNT5A/NDUFA2/PSMD14/ATP5MC1/IL1B/PSMC5/INSR/PSMC1	4.59572504801773
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	23/241	368/9376	2.43153526970954	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND1/MT-ND4/MT-ND2/MT-ATP6/MT-CO1/ACTB/MT-ND5/COX7A1/NDUFA13/NDUFC1/GPX3/NDUFA2/RAB1A/PSMD14/ATP5MC1/VCP/PSMC5/ACTR1A/PSMC1	4.55042181470304
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	17/241	227/9376	2.91355768000439	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND1/MT-ND4/MT-ND2/MT-ATP6/MT-CO1/MT-ND5/COX7A1/EGFR/NDUFA13/NDUFC1/NDUFA2/ATP5MC1/VEGFA	4.74031886388785
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	27/241	480/9376	2.18838174273859	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND1/MT-ND4/MT-ND2/MT-ATP6/MT-CO1/DKK1/MT-ND5/COX7A1/NDUFA13/UBA52/NDUFC1/UBE2G2/GPX3/WNT5A/NDUFA2/RAB1A/PSMD14/ATP5MC1/VCP/IL1B/PSMC5/ACTR1A/PSMC1	4.34129288301008
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	17/241	235/9376	2.81437273770636	MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND1/MT-ND4/MT-ND2/MT-ATP6/MT-CO1/ACTB/MT-ND5/COX7A1/NDUFA13/NDUFC1/MGLL/NDUFA2/ATP5MC1	4.57513034909738
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	10/241	95/9376	4.09521729635292	FLT1/HLA-DRA/CTSL/HLA-DRB5/CCL2/CTSK/ITGAL/VEGFA/IL1B/HLA-DRB1	4.92487762584391
NA	NA	hsa04518	Integrin signaling	13/241	154/9376	3.28415153311419	FN1/FLT1/ACTB/SPP1/FERMT2/EGFR/FBN1/ITGB8/COL6A3/ITGAL/LAMA4/VEGFA/LAMC1	4.6420797494067
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	16/241	233/9376	2.67155806457358	FN1/DCN/MYL9/FBLN1/ACTB/TPM1/VCAN/FBN1/TPM2/ITGB8/PDLIM1/COL6A3/PDLIM4/NID1/BGN/DSP	4.19657463624322
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	7/241	52/9376	5.23715288860517	APOE/NPC2/PLTP/APOC1/LRPAP1/LDLR/APOA1	4.97639170967892
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	8/241	70/9376	4.44623592175459	HLA-DRA/ACTB/HLA-DRB5/HLA-G/CAV1/ITGAL/EIF4G1/HLA-DRB1	4.70059013201557
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	10/241	110/9376	3.53677857412297	FLT1/TIMP1/SERPINE1/GAPDH/EGFR/ELOB/CREBBP/ELOC/VEGFA/INSR	4.34682983497685
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	8/241	78/9376	3.99021172465156	C1QB/C1QA/SERPING1/CD14/C1QC/C1R/C1S/IL1B	4.30719321515646
NA	NA	hsa03272	Virion - Hepatitis viruses	6/241	48/9376	4.86307053941909	CD63/CD81/EGFR/VPS4B/LDLR/CLDN5	4.35811686648537
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	10/241	142/9376	2.73975805037695	ACTB/CTSL/IL1R1/IL1R2/CAV1/CCL2/MMP2/GSTP1/VEGFA/IL1B	3.39295402948421
NA	NA	hsa04382	Cornified envelope formation	13/241	217/9376	2.33068818479071	S100A6/KRT8/KRT18/KRT19/KRT7/S100A11/S100A9/S100A13/S100A4/DST/CLDN5/DSP/COL17A1	3.22123212671249
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	8/241	100/9376	3.11236514522822	HLA-DRA/CD59/CD14/IL1R1/IL1R2/HLA-DRB5/IL1B/HLA-DRB1	3.4492804469818
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	5/241	42/9376	4.6314957518277	FTL/FTH1/SAT1/SLC40A1/GPX4	3.83103545292099
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	8/241	103/9376	3.02171373323128	FN1/HSPB1/CD14/IL1R1/IL1R2/LAMA4/IL1B/LAMC1	3.35095061414933
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	7/241	82/9376	3.32112134399352	HLA-DRA/CD74/CTSL/CTSB/HLA-DRB5/HLA-G/HLA-DRB1	3.42880921548629
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	14/241	250/9376	2.17865560165975	PSAP/CTSL/CTSB/CD63/CD68/HEXB/NPC2/CTSZ/CTSK/LAMTOR5/CTSD/CTSH/BLOC1S1/AP1S2	3.0680086541411
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	5/241	44/9376	4.42097321765372	HLA-DRA/HLA-DRB5/HLA-G/IL1B/HLA-DRB1	3.69426913073788
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	5/241	45/9376	4.32272936837252	HLA-DRA/HLA-DRB5/HLA-G/IL1B/HLA-DRB1	3.62891683840188
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	12/241	203/9376	2.29977720090755	FN1/FLT1/MYL9/ACTB/SPP1/EGFR/CAV1/ITGB8/COL6A3/LAMA4/VEGFA/LAMC1	3.04089287260154
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	12/241	204/9376	2.28850378325604	TIMP3/FN1/LUM/DCN/ACTB/CTSL/CD63/EGFR/CAV1/MMP2/WNT5A/VEGFA	3.02209868839994
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	10/241	155/9376	2.50997189131308	HLA-DRA/ACTB/CTSL/CD14/HLA-DRB5/HLA-G/C1R/FCGR2A/HGS/HLA-DRB1	3.07882911296172
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	7/241	87/9376	3.13025230123527	MT-CO2/MT-CO3/MT-CYB/MT-CO1/TPM1/COX7A1/TPM2	3.24224681011098
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	10/241	157/9376	2.47799772709253	MT-CO2/MT-CO3/MT-CYB/MT-CO1/COX7A1/NDUFA13/NDUFC1/NDUFA2/IL1B/INSR	3.03334332781044
Human Diseases	Immune disease	hsa05310	Asthma	4/241	32/9376	4.86307053941909	HLA-DRA/PRG2/HLA-DRB5/HLA-DRB1	3.5553396508127
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	5/241	50/9376	3.89045643153527	CD81/CCL2/HBB/ITGAL/IL1B	3.32846203591516
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	9/241	143/9376	2.44853901285437	HLA-DRA/C1QB/C1QA/C1QC/HLA-DRB5/C1R/C1S/FCGR2A/HLA-DRB1	2.83508889555701
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	4/241	37/9376	4.20589884490299	HBB/LAMA4/APOA1/IL1B	3.17351366716056
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	9/241	149/9376	2.3499401264307	MT-ND3/MT-ND1/MT-ND4/MT-ND2/MT-ND5/NDUFA13/NDUFC1/MGLL/NDUFA2	2.69784667656133
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	6/241	78/9376	2.99265879348867	HLA-DRA/HLA-DRB5/FCGR2A/NFKBIB/IL1B/HLA-DRB1	2.87028719895625
Human Diseases	Immune disease	hsa05330	Allograft rejection	4/241	39/9376	3.99021172465156	HLA-DRA/HLA-DRB5/HLA-G/HLA-DRB1	3.03927814949229
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	7/241	109/9376	2.49845825878412	HLA-DRA/EBI3/IL1R1/HLA-DRB5/NFKBIB/IL1B/HLA-DRB1	2.55580785639142
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	9/241	160/9376	2.18838174273859	HLA-DRA/VCAN/HLA-DRB5/HLA-G/ITGB8/ITGAL/GLG1/CLDN5/HLA-DRB1	2.46254748100224
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	15/241	333/9376	1.75245785204291	FN1/SPP1/EGFR/HLA-G/ITGB8/CREBBP/COL6A3/NFX1/WNT5A/TCF7L2/LAMA4/BCAP31/VEGFA/LAMC1/PSMC1	2.27084720488681
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	7/241	112/9376	2.43153526970954	HLA-DRA/HLA-DRB5/LDLR/LAMA4/NFKBIB/LAMC1/HLA-DRB1	2.47543583889433
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	6/241	89/9376	2.62277961676535	FN1/SPP1/ITGB8/COL6A3/LAMA4/LAMC1	2.49836972329092
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	12/241	250/9376	1.86741908713693	RAB31/EGFR/HLA-G/CAV1/FOLR2/VPS4B/DAB2/RABEP1/LDLR/RAB11B/HGS/EHD2	2.25786842429271
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	6/241	93/9376	2.50997189131308	MYL9/ACTB/EGFR/CREBBP/TCF7L2/INSR	2.37687337318168
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	9/241	173/9376	2.02393687189696	HLA-DRA/ACTB/HLA-DRB5/CCL2/CREBBP/NFKBIB/RAB11B/IL1B/HLA-DRB1	2.20785936448828
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	10/241	205/9376	1.89778362513916	HLA-DRA/HLA-DRB5/HLA-G/ITGAL/POLK/PSMD14/NFKBIB/PSMC5/PSMC1/HLA-DRB1	2.11096069672875
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	4/241	50/9376	3.11236514522822	AOC1/SAT1/MAOA/SMS	2.4324626087334
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	13/241	298/9376	1.69717898019995	PRL/IL1RL1/PRLR/CXCL14/EBI3/IL1R1/IL1R2/CCL2/CSH1/CCL21/CCL18/IL1B/TNFRSF11B	1.98653952887972
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	9/241	181/9376	1.93448109855345	HLA-DRA/CD74/CD14/HLA-DRB5/CREBBP/CTSD/FCGR2A/IL1B/HLA-DRB1	2.06192956476641
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	6/241	101/9376	2.31116223655561	FN1/SERPINE1/CCL2/MMP2/VEGFA/IL1B	2.15179078735046
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	6/241	103/9376	2.26628529992346	C1QB/C1QA/SERPINE1/C1QC/CCL2/IL1B	2.09884289438191
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	4/241	54/9376	2.88181957891501	HLA-DRA/HLA-DRB5/HLA-G/HLA-DRB1	2.25247612805334
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	6/241	106/9376	2.20214514992562	IL1R2/EGFR/FOLR2/CREBBP/TCF7L2/GSTP1	2.02166809727716
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	4/241	56/9376	2.77889745109662	CD14/RAB1A/VCP/IL1B	2.16858701906987
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	7/241	137/9376	1.98782445406912	ACTB/CTSL/CTSB/CTSZ/CTSK/CTSD/CTSH	1.89176617861066
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	4/241	59/9376	2.63759758070188	GPX4/GPX3/GSTP1/SMS	2.04943915748695
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	5/241	86/9376	2.26189327414841	ACTB/ITGB8/GJA1/TCF7L2/DSP	1.90943059861289
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	9/241	200/9376	1.75070539419087	ACTB/GAPDH/IL1R1/RAB1A/F2R/FCGR2A/NFKBIB/CLDN5/IL1B	1.74300131807296
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	6/241	116/9376	2.0123050507941	MYL9/ACTB/THY1/MMP2/ITGAL/CLDN5	1.78186496422523
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	4/241	63/9376	2.47013106764144	HPGD/PTGDS/GPX4/PTGES	1.90160982389349
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	14/241	362/9376	1.50459640998602	FN1/FLT1/PRL/SPP1/PRLR/EGFR/ITGB8/CSH1/COL6A3/F2R/LAMA4/VEGFA/LAMC1/INSR	1.59030179225648
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	3/241	41/9376	2.84667543770873	EGFR/MMP2/VEGFA	1.92470964936416
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	4/241	66/9376	2.35785238274865	HLA-DRA/HLA-DRB5/IL1B/HLA-DRB1	1.79799951249472
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	4/241	70/9376	2.2231179608773	ELOB/CREBBP/ELOC/VEGFA	1.66830604396452
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	2/241	22/9376	3.53677857412297	AOC1/MAOA	1.93479564962478
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	3/241	46/9376	2.53725419447952	PSMD14/PSMC5/PSMC1	1.6975542581273
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	10/241	253/9376	1.53772981483607	MYL9/ACTB/CD14/IL1R1/EGFR/UBA52/TNIP1/FBXW11/NFKBIB/IL1B	1.40830079266799
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	4/241	73/9376	2.13175694878645	MAP1B/VPS4B/CREBBP/HGS	1.57667787331852
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	3/241	50/9376	2.33427385892116	HLA-DRA/HLA-DRB5/HLA-DRB1	1.53646318155165
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	3/241	52/9376	2.2444940951165	LDLR/CYP11A1/INSR	1.46161591533244
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	5/241	110/9376	1.76838928706149	DCN/FBN1/EMP3/CREBBP/LTBP1	1.31665314109262
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	6/241	142/9376	1.64385483022617	ELOB/UBA52/UBE2G2/ELOC/DDB1/FBXW11	1.25567451183538
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	6/241	144/9376	1.6210235131397	C1QB/C1QA/CD14/C1QC/TCF7L2/IL1B	1.21977934636989
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	3/241	55/9376	2.12206714447378	PSAP/HEXB/PLPP3	1.35552902191422
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	2/241	30/9376	2.59363762102351	FOLR2/IL1B	1.4199635497577
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	7/241	180/9376	1.51295527893038	HLA-DRA/CD74/HLA-DRB5/HLA-G/CCL2/IL1B/HLA-DRB1	1.12864187242763
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	9/241	248/9376	1.41185918886361	MYL9/ACTB/GAPDH/CD14/ANXA2/TCF7L2/IL1B/ACTR1A/AHNAK2	1.06764450262512
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	3/241	59/9376	1.97819818552641	EGFR/POLK/TCF7L2	1.22420653817848
NA	NA	hsa04081	Hormone signaling	8/241	219/9376	1.42117129919097	PRL/RAMP1/PRLR/SLC40A1/ADRA2C/CSH1/DIO2/INSR	1.02433993007812
Organismal Systems	Digestive system	hsa04978	Mineral absorption	3/241	61/9376	1.9133392286239	FTL/FTH1/SLC40A1	1.16237291809514
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	4/241	93/9376	1.67331459420872	HLA-DRA/HLA-DRB5/NFKBIB/HLA-DRB1	1.05987637250494
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	4/241	93/9376	1.67331459420872	FN1/POLK/LAMA4/LAMC1	1.05987637250494
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	2/241	34/9376	2.28850378325604	RORB/FBXW11	1.2224894186304
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	8/241	224/9376	1.38944872554831	HLA-DRA/IL1R1/IL1R2/HLA-DRB5/HLA-G/CREBBP/ITGAL/HLA-DRB1	0.958200016622919
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	3/241	63/9376	1.85259830073108	WNT5A/POLK/TCF7L2	1.10283316922634
NA	NA	hsa04519	Cadherin signaling	13/241	404/9376	1.25187954480095	KRT8/ACTB/KRT18/KRT19/KRT7/EGFR/GJA1/CREBBP/WNT5A/CDH11/TCF7L2/LHFPL6/DSP	0.840579575989021
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	4/241	98/9376	1.58794140062664	MARCKS/GSN/PLPP3/FCGR2A	0.950297922983713
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	2/241	37/9376	2.1029494224515	POLK/TCF7L2	1.09180770687809
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	8/241	232/9376	1.3415367005294	FN1/MYL9/ACTB/EGFR/GSN/ITGB8/ITGAL/F2R	0.855565268042211
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	4/241	99/9376	1.5719015884991	ACTB/TPM1/TPM2/ITGB8	0.929126839161193
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	4/241	100/9376	1.55618257261411	CXCL14/CCL2/CCL21/CCL18	0.908190365194942
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	7/241	201/9376	1.35488532441527	IGFBP3/FLT1/NUPR1/HPGD/CD14/IL1R2/POLK	0.826081537889201
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	5/241	134/9376	1.45166284758779	CALD1/MYL9/RAMP1/MYL6/ADM	0.85531023502318
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	6/241	170/9376	1.37310226995362	ACTB/EGFR/WNT5A/POLK/TCF7L2/GSTP1	0.79736423214293
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	5/241	138/9376	1.40958566359974	FN1/ACTB/CCL2/FCGR2A/IL1B	0.78729083335179
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	4/241	105/9376	1.48207864058486	CD14/IL1R1/CCL21/IL1B	0.806843179830008
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	4/241	105/9376	1.48207864058486	ACTB/TPM1/TPM2/ITGB8	0.806843179830008
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	5/241	139/9376	1.39944475954506	KRT18/KRT19/EGFR/MMP2/CTSD	0.770616919095067
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	2/241	42/9376	1.85259830073108	AOC1/MAOA	0.899445997026718
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	5/241	142/9376	1.36987902518848	IL1R1/CTSK/FCGR2A/IL1B/TNFRSF11B	0.721354632423177
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	3/241	75/9376	1.55618257261411	IGFBP3/SERPINE1/CD82	0.78545818507583
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	2/241	43/9376	1.80951461931873	PLPP3/APOA1	0.864148090766555
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	7/241	212/9376	1.28458467078995	FLT1/ACTB/EGFR/ITGAL/F2R/VEGFA/INSR	0.68073295672558
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	4/241	109/9376	1.42769043359092	SPP1/CD14/CTSK/IL1B	0.72947949258333
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	6/241	178/9376	1.31138980838268	NOTUM/DKK1/CREBBP/WNT5A/FBXW11/TCF7L2	0.681251664542541
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	3/241	77/9376	1.5157622460527	EGFR/POLK/VEGFA	0.73810249072562
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/241	15/9376	2.59363762102351	HEXB	1.00326107854805
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/241	78/9376	1.49632939674433	FN1/ACTB/CAV1	0.714928174655929
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/241	46/9376	1.69150279631968	FTL/FTH1	0.763610547048697
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	3/241	80/9376	1.45892116182573	EGFR/AXL/VEGFA	0.669537496396253
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	1/241	16/9376	2.43153526970954	MAOA	0.930816349866526
Metabolism	Glycan biosynthesis and metabolism	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	1/241	16/9376	2.43153526970954	HEXB	0.930816349866526
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	5/241	155/9376	1.25498594565654	EGFR/WNT5A/TCF7L2/LDLR/CYP11A1	0.519915739756412
Metabolism	Glycan biosynthesis and metabolism	hsa00511	Other glycan degradation	1/241	18/9376	2.16136468418626	HEXB	0.801038207356117
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	5/241	157/9376	1.23899886354626	C1QB/C1QA/C1QC/MFGE8/AXL	0.490505225281008
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	5/241	157/9376	1.23899886354626	ACTB/SERPINE1/WNT5A/FBXW11/TCF7L2	0.490505225281008
Cellular Processes	Cell motility	hsa04814	Motor proteins	6/241	194/9376	1.20323394789751	MYL9/ACTB/TPM1/MYL6/TPM2/ACTR1A	0.464588395702666
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	3/241	87/9376	1.3415367005294	EGFR/POLK/TCF7L2	0.519819308344448
Metabolism	Glycan biosynthesis and metabolism	hsa00531	Glycosaminoglycan degradation	1/241	19/9376	2.04760864817646	HEXB	0.742416207555084
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/241	21/9376	1.85259830073108	CHPF	0.635290114986341
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	5/241	168/9376	1.15787393795693	PRL/PRLR/EGFR/CSH1/CREBBP	0.335368533042289
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	3/241	94/9376	1.24163503134104	S100A9/CCL2/IL1B	0.382422050063629
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	5/241	169/9376	1.15102261288026	CTSL/CTSB/UBA52/RAB1A/CTSD	0.321785258291801
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	4/241	133/9376	1.17006208467226	EGFR/CREBBP/DEPP1/INSR	0.32082390901737
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/241	59/9376	1.31879879035094	MGLL/INSR	0.398973918870017
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	2/241	60/9376	1.29681881051176	HSPB1/VEGFA	0.374621060745426
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	5/241	174/9376	1.11794725044117	CRYAB/UBE2G2/SSR4/BCAP31/VCP	0.255071076161737
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	6/241	214/9376	1.09078217706596	HLA-G/ELOB/ELOC/DDB1/FBXW11/AP1S2	0.218198730770879
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/241	62/9376	1.25498594565654	CRYAB/INSR	0.327177820632184
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	3/241	101/9376	1.1555811182778	CREBBP/WNT5A/TCF7L2	0.25532920920245
Organismal Systems	Digestive system	hsa04977	Vitamin digestion and absorption	1/241	26/9376	1.49632939674433	APOA1	0.411614580904805
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	3/241	103/9376	1.13314264996173	COL6A3/COL17A1/SLC1A5	0.220681314730767
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	2/241	65/9376	1.19706351739547	PLPP3/MGLL	0.258943270492315
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	2/241	65/9376	1.19706351739547	LDLR/CYP11A1	0.258943270492315
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	8/241	300/9376	1.03745504840941	FLT1/HSPB1/CD14/IL1R1/EGFR/VEGFA/IL1B/INSR	0.107093627691444
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	2/241	66/9376	1.17892619137432	HSD11B1/CYP11A1	0.236925021416796
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	2/241	68/9376	1.14425189162802	CD14/TCF7L2	0.193904402496796
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	4/241	148/9376	1.05147471122575	EGFR/WNT5A/POLK/TCF7L2	0.102520535812517
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	6/241	227/9376	1.02831447529567	IL1R1/EGFR/HLA-G/CCL2/VEGFA/IL1B	0.0701414139577042
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	4/241	149/9376	1.0444178339692	EGFR/PLPP3/F2R/INSR	0.0887687560415746
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	2/241	70/9376	1.11155898043865	HSD11B1/GSTP1	0.152163999938995
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	4/241	150/9376	1.03745504840941	EGFR/WNT5A/POLK/TCF7L2	0.0751085107274769
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/241	71/9376	1.09590322015078	PRL/PRLR	0.131748008463587
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	2/241	71/9376	1.09590322015078	EGFR/SLC1A5	0.131748008463587
NA	NA	hsa04981	Folate transport and metabolism	1/241	31/9376	1.25498594565654	FOLR2	0.23096561084151
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	5/241	193/9376	1.00789026723712	CXCL14/CCL2/CCL21/NFKBIB/CCL18	0.0179894530238584
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	4/241	154/9376	1.01050816403513	MYL9/ACTB/MYL6/EGFR	0.0213557352757757
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	2/241	73/9376	1.06587847439322	MAOA/GSTP1	0.0917768899189473
Human Diseases	Cancer: specific types	hsa05218	Melanoma	2/241	73/9376	1.06587847439322	EGFR/POLK	0.0917768899189473
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	2/241	73/9376	1.06587847439322	EGFR/POLK	0.0917768899189473
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	5/241	196/9376	0.992463375391651	HLA-G/UBA52/CREBBP/TCF7L2/VEGFA	-0.0173190259427152
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	4/241	156/9376	0.99755293116289	CD81/EGFR/LDLR/CLDN5	-0.00500590851813545
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	4/241	157/9376	0.991199090837011	IGFBP3/SERPINE1/HLA-G/FBXW11	-0.0180623952248784
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	2/241	76/9376	1.02380432408823	PLTP/APOA1	0.0338423926452439
Human Diseases	Cancer: specific types	hsa05214	Glioma	2/241	76/9376	1.02380432408823	EGFR/POLK	0.0338423926452439
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	2/241	79/9376	0.984925678869689	HSD11B1/GSTP1	-0.0218534383244447
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/241	36/9376	1.08068234209313	GALNT15	0.0787764113306248
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	5/241	205/9376	0.948891812569578	HLA-G/GSN/CREBBP/DDB1/PSMC1	-0.12017079831451
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	3/241	122/9376	0.956669614311952	ACTB/CREBBP/DIO2	-0.0782433805539335
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/241	122/9376	0.956669614311952	IGFBP3/CSH1/CREBBP	-0.0782433805539335
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/241	37/9376	1.05147471122575	MAOA	0.0509547267368627
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/241	38/9376	1.02380432408823	HEXB	0.023881445019799
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/241	38/9376	1.02380432408823	INSR	0.023881445019799
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	4/241	168/9376	0.92629915036554	FTL/FTH1/VPS4B/IL1B	-0.156561280131131
Organismal Systems	Immune system	hsa04611	Platelet activation	3/241	126/9376	0.92629915036554	ACTB/F2R/FCGR2A	-0.135277878664253
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	2/241	83/9376	0.937459381092836	NFKBIB/IL1B	-0.0929529411585852
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	4/241	170/9376	0.915401513302416	MYL9/ACTB/MYL6/CLDN5	-0.180797097252871
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	3/241	130/9376	0.897797638046601	EGFR/MMP2/VEGFA	-0.190587997930853
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	5/241	216/9376	0.900568618410942	CD14/CCL2/LDLR/APOA1/IL1B	-0.240127830049703
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/241	41/9376	0.948891812569578	MAOA	-0.0532678452857402
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	2/241	89/9376	0.874259872255117	EGFR/GJA1	-0.193584714101061
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/241	90/9376	0.864545873674504	EGFR/NFKBIB	-0.209719608416317
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/241	44/9376	0.884194643530743	HEXB	-0.125056855566935
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/241	44/9376	0.884194643530743	RAB11B	-0.125056855566935
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	2/241	91/9376	0.855045369568191	CD81/NFKBIB	-0.225684492727635
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/241	93/9376	0.836657297104359	EGFR/MMP2	-0.257120628171797
Organismal Systems	Digestive system	hsa04970	Salivary secretion	2/241	93/9376	0.836657297104359	CST3/LYZ	-0.257120628171797
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	4/241	184/9376	0.845751398159841	MYL9/SEMA3B/WNT5A/DPYSL2	-0.343214022643635
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/241	47/9376	0.827756687560696	INSR	-0.192270933541068
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	4/241	187/9376	0.832183193911288	CTSB/CCL2/NFKBIB/IL1B	-0.376497426890478
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	3/241	144/9376	0.810511756569848	PSMD14/PSMC5/PSMC1	-0.372182116821103
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/241	49/9376	0.79397070031332	GALNT15	-0.234852896925927
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/241	49/9376	0.79397070031332	MAOA	-0.234852896925927
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	2/241	98/9376	0.79397070031332	LDLR/CYP11A1	-0.333008043586256
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	2/241	99/9376	0.78595079424955	EGFR/MMP2	-0.347750147863409
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	2/241	99/9376	0.78595079424955	IL1R1/IL1B	-0.347750147863409
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/241	99/9376	0.78595079424955	EGFR/PLPP3	-0.347750147863409
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/241	51/9376	0.76283459441868	PLPP3	-0.275836600552556
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/241	51/9376	0.76283459441868	ACTB	-0.275836600552556
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	8/241	370/9376	0.841179768980599	PRL/NPW/PRLR/TAC3/ADM/ADRA2C/CSH1/F2R	-0.506268140169259
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/241	54/9376	0.720454894728754	SMS	-0.334606294563416
Genetic Information Processing	Replication and repair	hsa03460	Fanconi anemia pathway	1/241	54/9376	0.720454894728754	POLK	-0.334606294563416
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/241	105/9376	0.741039320292432	UBA52/VCP	-0.43341612897992
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/241	56/9376	0.694724362774155	FBXW11	-0.372150054922021
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	3/241	158/9376	0.738694259152266	WNT5A/LAMTOR5/INSR	-0.5380207511071
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/241	62/9376	0.627492972828269	CREBBP	-0.47797158783169
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/241	166/9376	0.703094535819627	MYL9/ADRA2C/INSR	-0.626876952284065
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/241	63/9376	0.61753276691036	KMT2C	-0.494720140107946
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/241	63/9376	0.61753276691036	DDB1	-0.494720140107946
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	2/241	117/9376	0.665035287441927	ACTB/BAZ1B	-0.5921746750465
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/241	119/9376	0.65385822378744	CCL2/IL1B	-0.617209000237362
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/241	65/9376	0.598531758697734	SPP1	-0.527532953717581
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	2/241	122/9376	0.637779742874634	RAB11B/INSR	-0.654075355494028
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/241	67/9376	0.580665139035115	GAPDH	-0.559482798285872
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/241	67/9376	0.580665139035115	CREBBP	-0.559482798285872
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/241	68/9376	0.57212594581401	ALDH1A2	-0.575151298776452
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/241	69/9376	0.563834265439894	CTSB	-0.590624034904172
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/241	69/9376	0.563834265439894	MAOA	-0.590624034904172
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	4/241	226/9376	0.688576359563765	MYL9/FXYD1/CREBBP/F2R	-0.769724186555737
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/241	70/9376	0.555779490219324	NFKBIB	-0.605907022073768
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	6/241	323/9376	0.72268540523875	TIMP3/TPM1/MARCKS/EGFR/CREBBP/VEGFA	-0.823792077993326
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/241	71/9376	0.54795161007539	EGFR	-0.621005999674495
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/241	72/9376	0.540341171046565	NFKBIB	-0.635926447638031
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/241	75/9376	0.518727524204703	GAPDH	-0.679667835668422
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/241	75/9376	0.518727524204703	GSTP1	-0.679667835668422
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/241	75/9376	0.518727524204703	GPX3	-0.679667835668422
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/241	133/9376	0.585031042336131	HLA-G/ITGAL	-0.782843297347283
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/241	76/9376	0.511902162044114	ACTB	-0.693924289560737
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	4/241	238/9376	0.65385822378744	FLT1/EGFR/VEGFA/INSR	-0.878530418479506
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/241	77/9376	0.505254082017567	POLK	-0.708026221643707
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/241	136/9376	0.57212594581401	NFKBIB/IL1B	-0.816374262358514
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/241	78/9376	0.498776465581445	TOB2	-0.721977841544283
Genetic Information Processing	Transcription	hsa03040	Spliceosome	4/241	243/9376	0.640404350870003	CTNNBL1/HNRNPM/SNIP1/DDX42	-0.922466747702186
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/241	140/9376	0.555779490219324	SERPINE1/SPP1	-0.860122969332554
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	3/241	195/9376	0.598531758697734	ACTB/ITGAL/FCGR2A	-0.920160086626174
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/241	82/9376	0.474445906284789	GSTP1	-0.776359548987151
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/241	83/9376	0.468729690546418	CREBBP	-0.789617030929085
NA	NA	hsa04517	IgSF CAM signaling	5/241	299/9376	0.650577998584493	MYL9/ACTB/MYL6/ITGAL/CLMP	-0.997365995154586
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/241	86/9376	0.452378654829682	EGFR	-0.828631845769531
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	4/241	254/9376	0.612670304178783	FLT1/EGFR/F2R/VEGFA	-1.01646517235476
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/241	90/9376	0.432272936837252	INSR	-0.878994982313998
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/241	90/9376	0.432272936837252	LDLR	-0.878994982313998
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	2/241	154/9376	0.505254082017567	TPM1/TPM2	-1.00547182341999
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	2/241	158/9376	0.492462839434844	CDKN1C/CREBBP	-1.04500392320561
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	2/241	163/9376	0.477356617366291	CREBBP/DDB1	-1.09329813251896
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/241	103/9376	0.37771421665391	UPF2	-1.03142640503666
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/241	104/9376	0.374082349186084	PLPP3	-1.04252634990915
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/241	105/9376	0.370519660146216	IL1B	-1.05354578338488
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/241	107/9376	0.363594059021988	CREBBP	-1.07534929972567
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/241	108/9376	0.360227447364377	UPF2	-1.08613636100003
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/241	109/9376	0.356922608397731	INSR	-1.09684887122476
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/241	115/9376	0.338300559263936	MAOA	-1.1596331698266
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/241	115/9376	0.338300559263936	EGFR	-1.1596331698266
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/241	116/9376	0.335384175132351	GAPDH	-1.16986046061147
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/241	120/9376	0.324204702627939	NFKBIB	-1.21013549342616
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/241	122/9376	0.318889871437317	NFKBIB	-1.22990733043412
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/241	125/9376	0.311236514522822	CTSD	-1.2591302703014
NA	NA	hsa04082	Neuroactive ligand signaling	2/241	199/9376	0.391000646385454	TAC3/ADRA2C	-1.41036943548047
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/241	133/9376	0.292515521168065	MAOA	-1.33467690052961
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/241	138/9376	0.281917132719947	FBXW11	-1.38027306431563
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/241	138/9376	0.281917132719947	INSR	-1.38027306431563
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/241	144/9376	0.270170585523283	WNT5A	-1.43348975894843
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	2/241	217/9376	0.358567413044725	EGFR/VEGFA	-1.55273284893981
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	1/241	183/9376	0.212593247624878	NHP2	-1.74717309455588
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/241	191/9376	0.203688818404988	MAOA	-1.8059253777714