ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005201 extracellular matrix structural constituent 27/364 168/18639 0.160714285714286 8.22954277864992 2.71382503019414e-17 1.87253927083396e-14 GO:0003735 structural constituent of ribosome 26/364 175/18639 0.148571428571429 7.60775510204082 7.74152731680373e-16 2.67082692429729e-13 GO:0019838 growth factor binding 20/364 136/18639 0.147058823529412 7.53030058177117 2.18297811851951e-12 5.02084967259488e-10 GO:0050840 extracellular matrix binding 14/364 67/18639 0.208955223880597 10.6997703788749 3.51037974837808e-11 6.05540506595219e-09 GO:0001968 fibronectin binding 10/364 30/18639 0.333333333333333 17.0686813186813 1.51435983968036e-10 2.08981657875889e-08 GO:0005518 collagen binding 13/364 72/18639 0.180555555555556 9.24553571428571 1.21743522492442e-09 1.21016748024238e-07 GO:0005520 insulin-like growth factor binding 8/364 19/18639 0.421052631578947 21.5604395604396 1.22770613937633e-09 1.21016748024238e-07 GO:0031994 insulin-like growth factor I binding 7/364 13/18639 0.538461538461538 27.5724852071006 1.5867908003003e-09 1.36860706525901e-07 GO:0061134 peptidase regulator activity 21/364 226/18639 0.0929203539823009 4.75808373042886 3.83860221141899e-09 2.94292836208789e-07 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 12/364 68/18639 0.176470588235294 9.0363606981254 6.99979436655941e-09 4.82985811292599e-07 GO:0005539 glycosaminoglycan binding 21/364 242/18639 0.0867768595041322 4.44349968213605 1.29688543132906e-08 8.13500861470044e-07 GO:0005178 integrin binding 17/364 161/18639 0.105590062111801 5.40684936181831 1.79989947575219e-08 1.03494219855751e-06 GO:0008201 heparin binding 16/364 172/18639 0.0930232558139535 4.76335292614362 2.77525876565676e-07 1.4730219602332e-05 GO:0033218 amide binding 19/364 247/18639 0.0769230769230769 3.93892645815723 4.25243185598982e-07 2.09584141473784e-05 GO:0001540 amyloid-beta binding 11/364 83/18639 0.132530120481928 6.78634317489739 6.22445863159472e-07 2.86325097053357e-05 GO:1901681 sulfur compound binding 19/364 275/18639 0.0690909090909091 3.53787212787213 2.14380967670737e-06 9.24517923080055e-05 GO:0009055 electron transfer activity 12/364 116/18639 0.103448275862069 5.29717696097006 2.8538351323971e-06 0.000115832131844353 GO:0030021 extracellular matrix structural constituent conferring compression resistance 6/364 22/18639 0.272727272727273 13.9652847152847 3.04880728779048e-06 0.000116870946031968 GO:0022853 active monoatomic ion transmembrane transporter activity 12/364 118/18639 0.101694915254237 5.20739430061464 3.41845639791535e-06 0.000119375491124531 GO:0061135 endopeptidase regulator activity 15/364 184/18639 0.0815217391304348 4.17440575728619 3.46015916302987e-06 0.000119375491124531 GO:0043394 proteoglycan binding 7/364 37/18639 0.189189189189189 9.68762993762994 6.35534367109137e-06 0.000208818434907288 GO:0008137 NADH dehydrogenase (ubiquinone) activity 7/364 41/18639 0.170731707317073 8.74249530956848 1.29770409746102e-05 0.000407007194203685 GO:0016504 peptidase activator activity 8/364 57/18639 0.140350877192982 7.18681318681319 1.40470637758285e-05 0.000421411913274855 GO:0002020 protease binding 12/364 136/18639 0.0882352941176471 4.5181803490627 1.4843508838443e-05 0.000426750879105235 GO:0015078 proton transmembrane transporter activity 14/364 185/18639 0.0756756756756757 3.87505197505198 1.71049618065133e-05 0.000455504122863128 GO:0004866 endopeptidase inhibitor activity 13/364 161/18639 0.0807453416149068 4.1346495119787 1.71639234702048e-05 0.000455504122863128 GO:0003954 NADH dehydrogenase activity 7/364 44/18639 0.159090909090909 8.14641608391608 2.10344079401211e-05 0.000537545980691985 GO:0004857 enzyme inhibitor activity 22/364 416/18639 0.0528846153846154 2.70801193998309 2.53558929982072e-05 0.0006170423781731 GO:0070325 lipoprotein particle receptor binding 6/364 31/18639 0.193548387096774 9.91084721729883 2.59336651695941e-05 0.0006170423781731 GO:0030414 peptidase inhibitor activity 13/364 169/18639 0.0769230769230769 3.93892645815723 2.87160135632008e-05 0.000660468311953618 GO:0042277 peptide binding 16/364 249/18639 0.0642570281124498 3.29034820601086 3.3298589555121e-05 0.000741162154613984 GO:0019843 rRNA binding 8/364 65/18639 0.123076923076923 6.30228233305156 3.74627274497381e-05 0.000807790060634979 GO:0015399 primary active transmembrane transporter activity 12/364 166/18639 0.072289156626506 3.70164173176221 0.000105606192337842 0.00220812947615487 GO:0008191 metalloendopeptidase inhibitor activity 4/364 14/18639 0.285714285714286 14.6302982731554 0.000122645825563214 0.00243519417691232 GO:0019955 cytokine binding 11/364 144/18639 0.0763888888888889 3.9115728021978 0.000125054147147243 0.00243519417691232 GO:0050750 low-density lipoprotein particle receptor binding 5/364 26/18639 0.192307692307692 9.84731614539307 0.000129649102202639 0.00243519417691232 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 7/364 58/18639 0.120689655172414 6.18003978779841 0.000130582876153269 0.00243519417691232 GO:0023026 MHC class II protein complex binding 5/364 27/18639 0.185185185185185 9.48260073260073 0.00015658367486964 0.00284322988579084 GO:0004129 cytochrome-c oxidase activity 4/364 15/18639 0.266666666666667 13.6549450549451 0.000164675609394383 0.00287940600584656 GO:0048306 calcium-dependent protein binding 8/364 80/18639 0.1 5.1206043956044 0.000166922087295453 0.00287940600584656 GO:0016675 oxidoreductase activity, acting on a heme group of donors 4/364 16/18639 0.25 12.801510989011 0.000216197299947733 0.00363844236497405 GO:0140375 immune receptor activity 11/364 156/18639 0.0705128205128205 3.61068258664413 0.000252818852745197 0.00415345258081394 GO:0016209 antioxidant activity 8/364 86/18639 0.0930232558139535 4.76335292614362 0.000276110428581944 0.00443060920282654 GO:0098641 cadherin binding involved in cell-cell adhesion 4/364 18/18639 0.222222222222222 11.3791208791209 0.00035243401355129 0.00552680612159978 GO:0004867 serine-type endopeptidase inhibitor activity 8/364 95/18639 0.0842105263157895 4.31208791208791 0.000543500564589864 0.00833367532371125 GO:0023023 MHC protein complex binding 5/364 37/18639 0.135135135135135 6.91973566973567 0.000720499615834002 0.0106690895905684 GO:0005125 cytokine activity 13/364 234/18639 0.0555555555555556 2.84478021978022 0.000726735088053213 0.0106690895905684 GO:0033293 monocarboxylic acid binding 7/364 79/18639 0.0886075949367089 4.53724440116845 0.000887521395810644 0.012758120064778 GO:0004602 glutathione peroxidase activity 4/364 23/18639 0.173913043478261 8.90539894887721 0.000944203039836039 0.0132959203568748 GO:0050786 RAGE receptor binding 3/364 11/18639 0.272727272727273 13.9652847152847 0.00108473960305161 0.0143936601174157 GO:0050998 nitric-oxide synthase binding 3/364 11/18639 0.272727272727273 13.9652847152847 0.00108473960305161 0.0143936601174157 GO:1990948 ubiquitin ligase inhibitor activity 3/364 11/18639 0.272727272727273 13.9652847152847 0.00108473960305161 0.0143936601174157 GO:0008307 structural constituent of muscle 5/364 42/18639 0.119047619047619 6.09595761381476 0.00129838653339709 0.0164094090008122 GO:0042056 chemoattractant activity 5/364 42/18639 0.119047619047619 6.09595761381476 0.00129838653339709 0.0164094090008122 GO:0120020 cholesterol transfer activity 4/364 25/18639 0.16 8.19296703296703 0.00130799636962995 0.0164094090008122 GO:0030547 signaling receptor inhibitor activity 5/364 44/18639 0.113636363636364 5.81886863136863 0.00160567759514105 0.0197842417972736 GO:0016651 oxidoreductase activity, acting on NAD(P)H 7/364 88/18639 0.0795454545454545 4.07320804195804 0.0016743542460486 0.0202684987679567 GO:0005504 fatty acid binding 5/364 47/18639 0.106382978723404 5.44745148468553 0.00216237672322933 0.0257248265349696 GO:0044548 S100 protein binding 3/364 14/18639 0.214285714285714 10.9727237048666 0.00229107996366718 0.0265599959523624 GO:0043236 laminin binding 4/364 29/18639 0.137931034482759 7.06290261462675 0.00230956486542282 0.0265599959523624 GO:0042562 hormone binding 7/364 94/18639 0.074468085106383 3.81321603927987 0.00244469727336194 0.0276531330921269 GO:0004896 cytokine receptor activity 7/364 96/18639 0.0729166666666667 3.73377403846154 0.00275424805956493 0.0306521155016097 GO:0055105 ubiquitin-protein transferase inhibitor activity 3/364 15/18639 0.2 10.2412087912088 0.00282268105223537 0.0307045959484141 GO:0005006 epidermal growth factor receptor activity 5/364 50/18639 0.1 5.1206043956044 0.00284796252275145 0.0307045959484141 GO:0071813 lipoprotein particle binding 4/364 32/18639 0.125 6.40075549450549 0.00333975651859875 0.0343945074303453 GO:0071814 protein-lipid complex binding 4/364 32/18639 0.125 6.40075549450549 0.00333975651859875 0.0343945074303453 GO:0120015 sterol transfer activity 4/364 32/18639 0.125 6.40075549450549 0.00333975651859875 0.0343945074303453 GO:0031406 carboxylic acid binding 10/364 187/18639 0.053475935828877 2.73829112064406 0.00381204610711861 0.0386810560869388 GO:0015485 cholesterol binding 5/364 54/18639 0.0925925925925926 4.74130036630037 0.00398999791587087 0.0398999791587087 GO:0043177 organic acid binding 10/364 189/18639 0.0529100529100529 2.70931449502878 0.00410908985287339 0.0405038856926092 GO:0019199 transmembrane receptor protein kinase activity 6/364 78/18639 0.0769230769230769 3.93892645815723 0.0041977633222053 0.0407951646805867 GO:0098632 cell-cell adhesion mediator activity 5/364 55/18639 0.0909090909090909 4.6550949050949 0.00432012490602505 0.0414011970160734 GO:0008083 growth factor activity 9/364 162/18639 0.0555555555555556 2.84478021978022 0.00463003962259234 0.043763388213544 GO:0004601 peroxidase activity 5/364 57/18639 0.087719298245614 4.49175824175824 0.00503800181130797 0.0469759628351689 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 5/364 59/18639 0.0847457627118644 4.3394952505122 0.00583654412600486 0.0536962059592447 GO:0005501 retinoid binding 4/364 38/18639 0.105263157894737 5.39010989010989 0.00625544195405592 0.0554431381172568 GO:0019840 isoprenoid binding 4/364 38/18639 0.105263157894737 5.39010989010989 0.00625544195405592 0.0554431381172568 GO:0004714 transmembrane receptor protein tyrosine kinase activity 5/364 60/18639 0.0833333333333333 4.26717032967033 0.00626748517847251 0.0554431381172568 GO:0004197 cysteine-type endopeptidase activity 6/364 88/18639 0.0681818181818182 3.49132117882118 0.00753540283693099 0.0658155437655998 GO:0005126 cytokine receptor binding 12/364 275/18639 0.0436363636363636 2.23444555444555 0.0080924755010803 0.0697976011968176 GO:0042287 MHC protein binding 4/364 41/18639 0.0975609756097561 4.9957116054677 0.00819910569182503 0.0698442336711021 GO:0140035 ubiquitin-like protein reader activity 3/364 22/18639 0.136363636363636 6.98264235764236 0.00863631380487747 0.071965483155216 GO:0038024 cargo receptor activity 5/364 65/18639 0.0769230769230769 3.93892645815723 0.00876101534063499 0.071965483155216 GO:0120013 lipid transfer activity 5/364 65/18639 0.0769230769230769 3.93892645815723 0.00876101534063499 0.071965483155216 GO:0043178 alcohol binding 6/364 92/18639 0.0652173913043478 3.33952460582895 0.00929622490098571 0.0754634727256487 GO:0017134 fibroblast growth factor binding 3/364 23/18639 0.130434782608696 6.67904921165791 0.00979013041963369 0.0785487208086889 GO:0032934 sterol binding 5/364 68/18639 0.0735294117647059 3.76515029088559 0.0105473746462678 0.0836515920221241 GO:0050431 transforming growth factor beta binding 3/364 24/18639 0.125 6.40075549450549 0.0110293286847068 0.0864799635505418 GO:0008009 chemokine activity 4/364 45/18639 0.0888888888888889 4.55164835164835 0.0113523814963744 0.0870349248055369 GO:0042605 peptide antigen binding 4/364 45/18639 0.0888888888888889 4.55164835164835 0.0113523814963744 0.0870349248055369 GO:0097110 scaffold protein binding 5/364 70/18639 0.0714285714285714 3.65757456828885 0.011867697876107 0.0899858410386138 GO:0019865 immunoglobulin binding 3/364 26/18639 0.115384615384615 5.90838968723584 0.0137679288549873 0.0995031412339614 GO:0043548 phosphatidylinositol 3-kinase binding 3/364 26/18639 0.115384615384615 5.90838968723584 0.0137679288549873 0.0995031412339614 GO:0004175 endopeptidase activity 15/364 405/18639 0.037037037037037 1.89652014652015 0.013843979499577 0.0995031412339614 GO:0045296 cadherin binding 13/364 334/18639 0.0389221556886228 1.9930496150556 0.0146152480090207 0.0995031412339614 GO:0005004 GPI-linked ephrin receptor activity 4/364 49/18639 0.0816326530612245 4.18008522090155 0.0151951048256455 0.0995031412339614 GO:0005008 hepatocyte growth factor receptor activity 4/364 49/18639 0.0816326530612245 4.18008522090155 0.0151951048256455 0.0995031412339614 GO:0005009 insulin receptor activity 4/364 49/18639 0.0816326530612245 4.18008522090155 0.0151951048256455 0.0995031412339614 GO:0005011 macrophage colony-stimulating factor receptor activity 4/364 49/18639 0.0816326530612245 4.18008522090155 0.0151951048256455 0.0995031412339614 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/364 49/18639 0.0816326530612245 4.18008522090155 0.0151951048256455 0.0995031412339614 GO:0005020 stem cell factor receptor activity 4/364 49/18639 0.0816326530612245 4.18008522090155 0.0151951048256455 0.0995031412339614 GO:0008288 boss receptor activity 4/364 49/18639 0.0816326530612245 4.18008522090155 0.0151951048256455 0.0995031412339614 GO:0036332 placental growth factor receptor activity 4/364 49/18639 0.0816326530612245 4.18008522090155 0.0151951048256455 0.0995031412339614 GO:0038062 protein tyrosine kinase collagen receptor activity 4/364 49/18639 0.0816326530612245 4.18008522090155 0.0151951048256455 0.0995031412339614 GO:0060175 brain-derived neurotrophic factor receptor activity 4/364 49/18639 0.0816326530612245 4.18008522090155 0.0151951048256455 0.0995031412339614 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/364 10/18639 0.2 10.2412087912088 0.0154301972638172 0.0995031412339614 GO:0032395 MHC class II receptor activity 2/364 10/18639 0.2 10.2412087912088 0.0154301972638172 0.0995031412339614 GO:0005007 fibroblast growth factor receptor activity 4/364 50/18639 0.08 4.09648351648352 0.0162687693737232 0.101596970949013 GO:0005017 platelet-derived growth factor receptor activity 4/364 50/18639 0.08 4.09648351648352 0.0162687693737232 0.101596970949013 GO:0005019 platelet-derived growth factor beta-receptor activity 4/364 50/18639 0.08 4.09648351648352 0.0162687693737232 0.101596970949013 GO:0017022 myosin binding 5/364 76/18639 0.0657894736842105 3.36881868131868 0.0164911025308542 0.101596970949013 GO:0098631 cell adhesion mediator activity 5/364 76/18639 0.0657894736842105 3.36881868131868 0.0164911025308542 0.101596970949013 GO:0005010 insulin-like growth factor receptor activity 4/364 51/18639 0.0784313725490196 4.01616031027796 0.0173888455939833 0.1043330735639 GO:0005021 vascular endothelial growth factor receptor activity 4/364 51/18639 0.0784313725490196 4.01616031027796 0.0173888455939833 0.1043330735639 GO:0005030 neurotrophin receptor activity 4/364 51/18639 0.0784313725490196 4.01616031027796 0.0173888455939833 0.1043330735639 GO:0003953 NAD+ nucleosidase activity 2/364 11/18639 0.181818181818182 9.31018981018981 0.0186180767439873 0.107053941277927 GO:0008199 ferric iron binding 2/364 11/18639 0.181818181818182 9.31018981018981 0.0186180767439873 0.107053941277927 GO:0019864 IgG binding 2/364 11/18639 0.181818181818182 9.31018981018981 0.0186180767439873 0.107053941277927 GO:0042608 T cell receptor binding 2/364 11/18639 0.181818181818182 9.31018981018981 0.0186180767439873 0.107053941277927 GO:0097493 structural molecule activity conferring elasticity 2/364 11/18639 0.181818181818182 9.31018981018981 0.0186180767439873 0.107053941277927 GO:0005496 steroid binding 6/364 108/18639 0.0555555555555556 2.84478021978022 0.0193000138664715 0.108266332267319 GO:0005003 ephrin receptor activity 4/364 53/18639 0.0754716981132075 3.86460709102219 0.01977037371838 0.108266332267319 GO:0005005 transmembrane-ephrin receptor activity 4/364 53/18639 0.0754716981132075 3.86460709102219 0.01977037371838 0.108266332267319 GO:0016860 intramolecular oxidoreductase activity 4/364 53/18639 0.0754716981132075 3.86460709102219 0.01977037371838 0.108266332267319 GO:0017046 peptide hormone binding 4/364 53/18639 0.0754716981132075 3.86460709102219 0.01977037371838 0.108266332267319 GO:0038064 collagen receptor activity 4/364 53/18639 0.0754716981132075 3.86460709102219 0.01977037371838 0.108266332267319 GO:0031210 phosphatidylcholine binding 3/364 30/18639 0.1 5.1206043956044 0.0203054599482301 0.110321002868337 GO:0001618 virus receptor activity 5/364 81/18639 0.0617283950617284 3.16086691086691 0.0211532909401576 0.114029458974287 GO:0004859 phospholipase inhibitor activity 2/364 12/18639 0.166666666666667 8.53434065934066 0.0220565987132415 0.116796102021436 GO:0097371 MDM2/MDM4 family protein binding 2/364 12/18639 0.166666666666667 8.53434065934066 0.0220565987132415 0.116796102021436 GO:0140272 exogenous protein binding 5/364 82/18639 0.0609756097560976 3.12231975341731 0.0221785604358951 0.116796102021436 GO:0140313 molecular sequestering activity 4/364 55/18639 0.0727272727272727 3.72407592407592 0.02234360212584 0.116796102021436 GO:0005200 structural constituent of cytoskeleton 6/364 112/18639 0.0535714285714286 2.74318092621664 0.022636699833795 0.117438517934726 GO:0001221 transcription coregulator binding 6/364 115/18639 0.0521739130434783 2.67161968466316 0.0253798984171795 0.130687536625775 GO:0008035 high-density lipoprotein particle binding 2/364 13/18639 0.153846153846154 7.87785291631446 0.0257348138419214 0.13153349296982 GO:0008237 metallopeptidase activity 8/364 184/18639 0.0434782608695652 2.2263497372193 0.0284073411230539 0.144125480697847 GO:0005161 platelet-derived growth factor receptor binding 2/364 14/18639 0.142857142857143 7.31514913657771 0.0296421028216304 0.148210514108152 GO:0032036 myosin heavy chain binding 2/364 14/18639 0.142857142857143 7.31514913657771 0.0296421028216304 0.148210514108152 GO:0051082 unfolded protein binding 6/364 121/18639 0.0495867768595041 2.53914267550631 0.0315110068757379 0.156421544922728 GO:0055106 ubiquitin-protein transferase regulator activity 3/364 36/18639 0.0833333333333333 4.26717032967033 0.0327921788796279 0.160841551097371 GO:0072341 modified amino acid binding 5/364 91/18639 0.0549450549450549 2.81351889868373 0.0328676213112019 0.160841551097371 GO:0005523 tropomyosin binding 2/364 15/18639 0.133333333333333 6.82747252747253 0.0337681677092296 0.162937312722856 GO:0051371 muscle alpha-actinin binding 2/364 15/18639 0.133333333333333 6.82747252747253 0.0337681677092296 0.162937312722856 GO:0005507 copper ion binding 4/364 63/18639 0.0634920634920635 3.25117739403454 0.0346114565834582 0.165846562795737 GO:0016410 N-acyltransferase activity 5/364 94/18639 0.0531914893617021 2.72372574234276 0.0370343083952423 0.17623222615667 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/364 16/18639 0.125 6.40075549450549 0.0381030234815819 0.177642474339808 GO:0055102 lipase inhibitor activity 2/364 16/18639 0.125 6.40075549450549 0.0381030234815819 0.177642474339808 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/364 16/18639 0.125 6.40075549450549 0.0381030234815819 0.177642474339808 GO:0000217 DNA secondary structure binding 3/364 39/18639 0.0769230769230769 3.93892645815723 0.0402303419171914 0.186301583374913 GO:0016500 protein-hormone receptor activity 4/364 67/18639 0.0597014925373134 3.0570772511071 0.0419551801801077 0.189675399381862 GO:0008429 phosphatidylethanolamine binding 2/364 17/18639 0.117647058823529 6.02424046541694 0.0426369897961493 0.189675399381862 GO:0030169 low-density lipoprotein particle binding 2/364 17/18639 0.117647058823529 6.02424046541694 0.0426369897961493 0.189675399381862 GO:0038191 neuropilin binding 2/364 17/18639 0.117647058823529 6.02424046541694 0.0426369897961493 0.189675399381862 GO:0048038 quinone binding 2/364 17/18639 0.117647058823529 6.02424046541694 0.0426369897961493 0.189675399381862 GO:0070492 oligosaccharide binding 2/364 17/18639 0.117647058823529 6.02424046541694 0.0426369897961493 0.189675399381862 GO:0050997 quaternary ammonium group binding 3/364 40/18639 0.075 3.8404532967033 0.0428831337732906 0.189675399381862 GO:0035615 clathrin adaptor activity 2/364 18/18639 0.111111111111111 5.68956043956044 0.0473606829526577 0.208145676670916 GO:0048156 tau protein binding 3/364 43/18639 0.0697674418604651 3.57251469460772 0.0513504653320732 0.218613701577556 GO:0003756 protein disulfide isomerase activity 2/364 19/18639 0.105263157894737 5.39010989010989 0.052265008051153 0.218613701577556 GO:0008301 DNA binding, bending 2/364 19/18639 0.105263157894737 5.39010989010989 0.052265008051153 0.218613701577556 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/364 19/18639 0.105263157894737 5.39010989010989 0.052265008051153 0.218613701577556 GO:0016918 retinal binding 2/364 19/18639 0.105263157894737 5.39010989010989 0.052265008051153 0.218613701577556 GO:0097001 ceramide binding 2/364 19/18639 0.105263157894737 5.39010989010989 0.052265008051153 0.218613701577556 GO:0140036 ubiquitin-modified protein reader activity 2/364 19/18639 0.105263157894737 5.39010989010989 0.052265008051153 0.218613701577556 GO:0042379 chemokine receptor binding 4/364 72/18639 0.0555555555555556 2.84478021978022 0.0522771895076765 0.218613701577556 GO:0001223 transcription coactivator binding 3/364 44/18639 0.0681818181818182 3.49132117882118 0.0543394274595896 0.225868704500704 GO:0004713 protein tyrosine kinase activity 6/364 140/18639 0.0428571428571429 2.19454474097331 0.0569608203898605 0.234114759916529 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/364 20/18639 0.1 5.1206043956044 0.0573411513418745 0.234114759916529 GO:0042288 MHC class I protein binding 2/364 20/18639 0.1 5.1206043956044 0.0573411513418745 0.234114759916529 GO:0004252 serine-type endopeptidase activity 7/364 176/18639 0.0397727272727273 2.03660402097902 0.0578016220845253 0.234606583754838 GO:0051010 microtubule plus-end binding 2/364 21/18639 0.0952380952380952 4.87676609105181 0.0625805727624778 0.249598816220287 GO:0072542 protein phosphatase activator activity 2/364 21/18639 0.0952380952380952 4.87676609105181 0.0625805727624778 0.249598816220287 GO:0140312 cargo adaptor activity 2/364 21/18639 0.0952380952380952 4.87676609105181 0.0625805727624778 0.249598816220287 GO:0005543 phospholipid binding 15/364 497/18639 0.0301810865191147 1.54545404293895 0.064459103969721 0.254520117393485 GO:0004222 metalloendopeptidase activity 5/364 110/18639 0.0454545454545455 2.32754745254745 0.0645522036867533 0.254520117393485 GO:0022804 active transmembrane transporter activity 14/364 457/18639 0.0306345733041575 1.56867530718734 0.0657361464790241 0.257715574264356 GO:0001664 G protein-coupled receptor binding 10/364 297/18639 0.0336700336700337 1.72410922410922 0.0673180576806723 0.262026531140693 GO:0008649 rRNA methyltransferase activity 2/364 22/18639 0.0909090909090909 4.6550949050949 0.0679749986582378 0.262026531140693 GO:0061133 endopeptidase activator activity 2/364 22/18639 0.0909090909090909 4.6550949050949 0.0679749986582378 0.262026531140693 GO:0005212 structural constituent of eye lens 2/364 23/18639 0.0869565217391304 4.4526994744386 0.073516414680962 0.280255945468861 GO:0140102 catalytic activity, acting on a rRNA 2/364 23/18639 0.0869565217391304 4.4526994744386 0.073516414680962 0.280255945468861 GO:0048020 CCR chemokine receptor binding 3/364 50/18639 0.06 3.07236263736264 0.0739449379565875 0.280340698846403 GO:0035401 histone H3Y41 kinase activity 5/364 115/18639 0.0434782608695652 2.2263497372193 0.0749904296565441 0.28121411121204 GO:0140801 histone H2AXY142 kinase activity 5/364 115/18639 0.0434782608695652 2.2263497372193 0.0749904296565441 0.28121411121204 GO:0005080 protein kinase C binding 3/364 52/18639 0.0576923076923077 2.95419484361792 0.0810872742913032 0.302433617627023 GO:0001848 complement binding 2/364 25/18639 0.08 4.09648351648352 0.0850094148583484 0.313671102953264 GO:0019211 phosphatase activator activity 2/364 25/18639 0.08 4.09648351648352 0.0850094148583484 0.313671102953264 GO:0008236 serine-type peptidase activity 7/364 194/18639 0.0360824742268041 1.84764076130055 0.0867247462182558 0.318298270694662 GO:0008198 ferrous iron binding 2/364 26/18639 0.0769230769230769 3.93892645815723 0.0909462053586285 0.328549118834836 GO:0030247 polysaccharide binding 2/364 26/18639 0.0769230769230769 3.93892645815723 0.0909462053586285 0.328549118834836 GO:0120014 phospholipid transfer activity 2/364 26/18639 0.0769230769230769 3.93892645815723 0.0909462053586285 0.328549118834836 GO:0017171 serine hydrolase activity 7/364 198/18639 0.0353535353535354 1.81031468531469 0.0940971955205376 0.338161796401932 GO:0003779 actin binding 13/364 443/18639 0.0293453724604966 1.50266043211867 0.0956417906300533 0.341931790335424 GO:0004364 glutathione transferase activity 2/364 27/18639 0.0740740740740741 3.79304029304029 0.0970003856604303 0.34500137167885 GO:0045499 chemorepellent activity 2/364 28/18639 0.0714285714285714 3.65757456828885 0.103165137399823 0.361339821349632 GO:0046625 sphingolipid binding 2/364 28/18639 0.0714285714285714 3.65757456828885 0.103165137399823 0.361339821349632 GO:0051393 alpha-actinin binding 2/364 28/18639 0.0714285714285714 3.65757456828885 0.103165137399823 0.361339821349632 GO:0001786 phosphatidylserine binding 3/364 59/18639 0.0508474576271186 2.60369715030732 0.108259397193076 0.3772675962789 GO:0051861 glycolipid binding 2/364 29/18639 0.0689655172413793 3.53145130731338 0.109433862438541 0.379444045641172 GO:0005516 calmodulin binding 7/364 207/18639 0.0338164251207729 1.73160535117057 0.111915820431983 0.386109580490342 GO:0048019 receptor antagonist activity 2/364 30/18639 0.0666666666666667 3.41373626373626 0.115800176902135 0.396308408614292 GO:0051015 actin filament binding 7/364 209/18639 0.0334928229665072 1.71503496503496 0.116102559630406 0.396308408614292 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/364 61/18639 0.0491803278688525 2.51833003062511 0.11659508253435 0.396308408614292 GO:0072349 modified amino acid transmembrane transporter activity 2/364 31/18639 0.0645161290322581 3.30361573909961 0.122257905365959 0.413519385796624 GO:0003823 antigen binding 6/364 174/18639 0.0344827586206897 1.76572565365669 0.126245655615132 0.424924401826543 GO:0030296 protein tyrosine kinase activator activity 2/364 33/18639 0.0606060606060606 3.1033966033966 0.135423910967869 0.451029788796019 GO:0140311 protein sequestering activity 2/364 33/18639 0.0606060606060606 3.1033966033966 0.135423910967869 0.451029788796019 GO:0005319 lipid transporter activity 6/364 178/18639 0.0337078651685393 1.72604642548463 0.136304486538273 0.451029788796019 GO:0070851 growth factor receptor binding 5/364 139/18639 0.0359712230215827 1.84194402719583 0.136616269359954 0.451029788796019 GO:0008238 exopeptidase activity 4/364 102/18639 0.0392156862745098 2.00808015513898 0.139118643133857 0.457104113154103 GO:0008376 acetylgalactosaminyltransferase activity 2/364 34/18639 0.0588235294117647 3.01212023270847 0.142120829180454 0.460391418471893 GO:0015035 protein-disulfide reductase activity 2/364 34/18639 0.0588235294117647 3.01212023270847 0.142120829180454 0.460391418471893 GO:0051427 hormone receptor binding 2/364 34/18639 0.0588235294117647 3.01212023270847 0.142120829180454 0.460391418471893 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 10/364 349/18639 0.0286532951289398 1.46722188985799 0.147230532634096 0.474715268773488 GO:0008080 N-acetyltransferase activity 3/364 69/18639 0.0434782608695652 2.2263497372193 0.152130736781192 0.488233527344291 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/364 36/18639 0.0555555555555556 2.84478021978022 0.155715506660219 0.497424535164588 GO:0019888 protein phosphatase regulator activity 4/364 107/18639 0.0373831775700935 1.9142446338708 0.157185335247947 0.499805904705454 GO:0008234 cysteine-type peptidase activity 6/364 187/18639 0.0320855614973262 1.64297467238644 0.160249249142602 0.500640732582196 GO:0042805 actinin binding 2/364 37/18639 0.0540540540540541 2.76789426789427 0.162603011508272 0.500640732582196 GO:0140597 protein carrier chaperone 6/364 188/18639 0.0319148936170213 1.63423544540566 0.163016546822164 0.500640732582196 GO:0000510 H3-H4 histone complex chaperone activity 5/364 151/18639 0.033112582781457 1.69556436940543 0.173772109661623 0.500640732582196 GO:0140584 chromatin extrusion motor activity 5/364 151/18639 0.033112582781457 1.69556436940543 0.173772109661623 0.500640732582196 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/364 151/18639 0.033112582781457 1.69556436940543 0.173772109661623 0.500640732582196 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/364 151/18639 0.033112582781457 1.69556436940543 0.173772109661623 0.500640732582196 GO:0003684 damaged DNA binding 3/364 74/18639 0.0405405405405405 2.0759207009207 0.175867062839629 0.500640732582196 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/364 39/18639 0.0512820512820513 2.62595097210482 0.176534011871463 0.500640732582196 GO:0015616 DNA translocase activity 5/364 152/18639 0.0328947368421053 1.68440934065934 0.177030868636104 0.500640732582196 GO:0140674 ATP-dependent histone chaperone activity 5/364 152/18639 0.0328947368421053 1.68440934065934 0.177030868636104 0.500640732582196 GO:0001094 TFIID-class transcription factor complex binding 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0003796 lysozyme activity 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0004935 adrenergic receptor activity 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0004955 prostaglandin receptor activity 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0005131 growth hormone receptor binding 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0005381 iron ion transmembrane transporter activity 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0008190 eukaryotic initiation factor 4E binding 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0030957 Tat protein binding 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0031720 haptoglobin binding 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0033204 ribonuclease P RNA binding 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0035374 chondroitin sulfate binding 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0042975 peroxisome proliferator activated receptor binding 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0043121 neurotrophin binding 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0043208 glycosphingolipid binding 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0043295 glutathione binding 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0140999 histone H3K4 trimethyltransferase activity 1/364 10/18639 0.1 5.1206043956044 0.179030767060206 0.500640732582196 GO:0044389 ubiquitin-like protein ligase binding 9/364 322/18639 0.0279503105590062 1.43122483106955 0.180291715330818 0.500640732582196 GO:0061775 cohesin loader activity 5/364 153/18639 0.0326797385620915 1.67340012928248 0.180312709845481 0.500640732582196 GO:0044183 protein folding chaperone 3/364 75/18639 0.04 2.04824175824176 0.180733384312775 0.500640732582196 GO:0030246 carbohydrate binding 8/364 280/18639 0.0285714285714286 1.46302982731554 0.183287796689149 0.500640732582196 GO:0004177 aminopeptidase activity 2/364 40/18639 0.05 2.5603021978022 0.183568268613472 0.500640732582196 GO:0015036 disulfide oxidoreductase activity 2/364 40/18639 0.05 2.5603021978022 0.183568268613472 0.500640732582196 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/364 40/18639 0.05 2.5603021978022 0.183568268613472 0.500640732582196 GO:0003724 RNA helicase activity 3/364 77/18639 0.038961038961039 1.9950406736121 0.19057280875383 0.505674092140149 GO:0001851 complement component C3b binding 1/364 11/18639 0.0909090909090909 4.6550949050949 0.195072036091829 0.505674092140149 GO:0004954 prostanoid receptor activity 1/364 11/18639 0.0909090909090909 4.6550949050949 0.195072036091829 0.505674092140149 GO:0008432 JUN kinase binding 1/364 11/18639 0.0909090909090909 4.6550949050949 0.195072036091829 0.505674092140149 GO:0008526 phosphatidylinositol transfer activity 1/364 11/18639 0.0909090909090909 4.6550949050949 0.195072036091829 0.505674092140149 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/364 11/18639 0.0909090909090909 4.6550949050949 0.195072036091829 0.505674092140149 GO:0019107 myristoyltransferase activity 1/364 11/18639 0.0909090909090909 4.6550949050949 0.195072036091829 0.505674092140149 GO:0032050 clathrin heavy chain binding 1/364 11/18639 0.0909090909090909 4.6550949050949 0.195072036091829 0.505674092140149 GO:0034511 U3 snoRNA binding 1/364 11/18639 0.0909090909090909 4.6550949050949 0.195072036091829 0.505674092140149 GO:0034713 type I transforming growth factor beta receptor binding 1/364 11/18639 0.0909090909090909 4.6550949050949 0.195072036091829 0.505674092140149 GO:0048185 activin binding 1/364 11/18639 0.0909090909090909 4.6550949050949 0.195072036091829 0.505674092140149 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/364 11/18639 0.0909090909090909 4.6550949050949 0.195072036091829 0.505674092140149 GO:1900750 oligopeptide binding 1/364 11/18639 0.0909090909090909 4.6550949050949 0.195072036091829 0.505674092140149 GO:0019208 phosphatase regulator activity 4/364 117/18639 0.0341880341880342 1.75063398140321 0.195673887828144 0.505674092140149 GO:0140658 ATP-dependent chromatin remodeler activity 5/364 158/18639 0.0316455696202532 1.62044442898873 0.197053207005045 0.507338480721945 GO:0019207 kinase regulator activity 8/364 287/18639 0.0278745644599303 1.42734617299077 0.200472311165726 0.512502742186599 GO:0008186 ATP-dependent activity, acting on RNA 3/364 79/18639 0.0379746835443038 1.94453331478648 0.200544551290408 0.512502742186599 GO:0003689 DNA clamp loader activity 5/364 160/18639 0.03125 1.60018887362637 0.203895917147093 0.519144586094076 GO:0004526 ribonuclease P activity 1/364 12/18639 0.0833333333333333 4.26717032967033 0.210800712217155 0.528918150653952 GO:0008179 adenylate cyclase binding 1/364 12/18639 0.0833333333333333 4.26717032967033 0.210800712217155 0.528918150653952 GO:0045295 gamma-catenin binding 1/364 12/18639 0.0833333333333333 4.26717032967033 0.210800712217155 0.528918150653952 GO:1990459 transferrin receptor binding 1/364 12/18639 0.0833333333333333 4.26717032967033 0.210800712217155 0.528918150653952 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/364 44/18639 0.0454545454545455 2.32754745254745 0.212063207981686 0.530158019954216 GO:0140104 molecular carrier activity 7/364 249/18639 0.0281124497991968 1.43952734012975 0.215310479369757 0.531510793755856 GO:0140713 histone chaperone activity 5/364 164/18639 0.0304878048780488 1.56115987670866 0.217813112897252 0.531510793755856 GO:0004860 protein kinase inhibitor activity 3/364 84/18639 0.0357142857142857 1.82878728414443 0.22597526645195 0.531510793755856 GO:0051117 ATPase binding 3/364 84/18639 0.0357142857142857 1.82878728414443 0.22597526645195 0.531510793755856 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/364 13/18639 0.0769230769230769 3.93892645815723 0.226222870415091 0.531510793755856 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/364 13/18639 0.0769230769230769 3.93892645815723 0.226222870415091 0.531510793755856 GO:0005172 vascular endothelial growth factor receptor binding 1/364 13/18639 0.0769230769230769 3.93892645815723 0.226222870415091 0.531510793755856 GO:0005542 folic acid binding 1/364 13/18639 0.0769230769230769 3.93892645815723 0.226222870415091 0.531510793755856 GO:0035325 Toll-like receptor binding 1/364 13/18639 0.0769230769230769 3.93892645815723 0.226222870415091 0.531510793755856 GO:0035673 oligopeptide transmembrane transporter activity 1/364 13/18639 0.0769230769230769 3.93892645815723 0.226222870415091 0.531510793755856 GO:0039706 co-receptor binding 1/364 13/18639 0.0769230769230769 3.93892645815723 0.226222870415091 0.531510793755856 GO:0043560 insulin receptor substrate binding 1/364 13/18639 0.0769230769230769 3.93892645815723 0.226222870415091 0.531510793755856 GO:0045159 myosin II binding 1/364 13/18639 0.0769230769230769 3.93892645815723 0.226222870415091 0.531510793755856 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/364 13/18639 0.0769230769230769 3.93892645815723 0.226222870415091 0.531510793755856 GO:1901338 catecholamine binding 1/364 13/18639 0.0769230769230769 3.93892645815723 0.226222870415091 0.531510793755856 GO:0004180 carboxypeptidase activity 2/364 46/18639 0.0434782608695652 2.2263497372193 0.226469816469886 0.531510793755856 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/364 46/18639 0.0434782608695652 2.2263497372193 0.226469816469886 0.531510793755856 GO:0030291 protein serine/threonine kinase inhibitor activity 2/364 46/18639 0.0434782608695652 2.2263497372193 0.226469816469886 0.531510793755856 GO:0019887 protein kinase regulator activity 7/364 255/18639 0.0274509803921569 1.40565610859728 0.232349244368996 0.543460944456296 GO:0061733 protein-lysine-acetyltransferase activity 2/364 47/18639 0.0425531914893617 2.17898059387421 0.233699983495191 0.544773610174601 GO:0003713 transcription coactivator activity 7/364 256/18639 0.02734375 1.40016526442308 0.235232638969786 0.546500070333847 GO:0004065 arylsulfatase activity 1/364 14/18639 0.0714285714285714 3.65757456828885 0.24134446792228 0.547788430481491 GO:0005344 oxygen carrier activity 1/364 14/18639 0.0714285714285714 3.65757456828885 0.24134446792228 0.547788430481491 GO:0008195 phosphatidate phosphatase activity 1/364 14/18639 0.0714285714285714 3.65757456828885 0.24134446792228 0.547788430481491 GO:0019763 immunoglobulin receptor activity 1/364 14/18639 0.0714285714285714 3.65757456828885 0.24134446792228 0.547788430481491 GO:0019992 diacylglycerol binding 1/364 14/18639 0.0714285714285714 3.65757456828885 0.24134446792228 0.547788430481491 GO:0043176 amine binding 1/364 14/18639 0.0714285714285714 3.65757456828885 0.24134446792228 0.547788430481491 GO:0061783 peptidoglycan muralytic activity 1/364 14/18639 0.0714285714285714 3.65757456828885 0.24134446792228 0.547788430481491 GO:0001222 transcription corepressor binding 2/364 49/18639 0.0408163265306122 2.09004261045077 0.248197070707159 0.548704792670656 GO:0016798 hydrolase activity, acting on glycosyl bonds 4/364 130/18639 0.0307692307692308 1.57557058326289 0.249382114688051 0.548704792670656 GO:0003727 single-stranded RNA binding 3/364 89/18639 0.0337078651685393 1.72604642548463 0.25197965567132 0.548704792670656 GO:0004953 icosanoid receptor activity 1/364 15/18639 0.0666666666666667 3.41373626373626 0.256171346508927 0.548704792670656 GO:0005041 low-density lipoprotein particle receptor activity 1/364 15/18639 0.0666666666666667 3.41373626373626 0.256171346508927 0.548704792670656 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/364 15/18639 0.0666666666666667 3.41373626373626 0.256171346508927 0.548704792670656 GO:0015929 hexosaminidase activity 1/364 15/18639 0.0666666666666667 3.41373626373626 0.256171346508927 0.548704792670656 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/364 15/18639 0.0666666666666667 3.41373626373626 0.256171346508927 0.548704792670656 GO:0031386 protein tag activity 1/364 15/18639 0.0666666666666667 3.41373626373626 0.256171346508927 0.548704792670656 GO:0033130 acetylcholine receptor binding 1/364 15/18639 0.0666666666666667 3.41373626373626 0.256171346508927 0.548704792670656 GO:0042809 nuclear vitamin D receptor binding 1/364 15/18639 0.0666666666666667 3.41373626373626 0.256171346508927 0.548704792670656 GO:0047372 monoacylglycerol lipase activity 1/364 15/18639 0.0666666666666667 3.41373626373626 0.256171346508927 0.548704792670656 GO:0061578 K63-linked deubiquitinase activity 1/364 15/18639 0.0666666666666667 3.41373626373626 0.256171346508927 0.548704792670656 GO:0120283 protein serine/threonine kinase binding 1/364 15/18639 0.0666666666666667 3.41373626373626 0.256171346508927 0.548704792670656 GO:0140161 monocarboxylate:sodium symporter activity 1/364 15/18639 0.0666666666666667 3.41373626373626 0.256171346508927 0.548704792670656 GO:0141047 molecular tag activity 1/364 15/18639 0.0666666666666667 3.41373626373626 0.256171346508927 0.548704792670656 GO:0019210 kinase inhibitor activity 3/364 90/18639 0.0333333333333333 1.70686813186813 0.257234275416335 0.548704792670656 GO:0005179 hormone activity 4/364 132/18639 0.0303030303030303 1.5516983016983 0.257921475937323 0.548704792670656 GO:0003743 translation initiation factor activity 2/364 51/18639 0.0392156862745098 2.00808015513898 0.262721979606155 0.548704792670656 GO:0051087 protein-folding chaperone binding 4/364 134/18639 0.0298507462686567 1.52853862555355 0.266518178765418 0.548704792670656 GO:0005024 transforming growth factor beta receptor activity 1/364 16/18639 0.0625 3.20037774725275 0.270709234710749 0.548704792670656 GO:0005149 interleukin-1 receptor binding 1/364 16/18639 0.0625 3.20037774725275 0.270709234710749 0.548704792670656 GO:0005159 insulin-like growth factor receptor binding 1/364 16/18639 0.0625 3.20037774725275 0.270709234710749 0.548704792670656 GO:0005521 lamin binding 1/364 16/18639 0.0625 3.20037774725275 0.270709234710749 0.548704792670656 GO:0008142 oxysterol binding 1/364 16/18639 0.0625 3.20037774725275 0.270709234710749 0.548704792670656 GO:0015378 sodium:chloride symporter activity 1/364 16/18639 0.0625 3.20037774725275 0.270709234710749 0.548704792670656 GO:0015562 efflux transmembrane transporter activity 1/364 16/18639 0.0625 3.20037774725275 0.270709234710749 0.548704792670656 GO:0016722 oxidoreductase activity, acting on metal ions 1/364 16/18639 0.0625 3.20037774725275 0.270709234710749 0.548704792670656 GO:0019841 retinol binding 1/364 16/18639 0.0625 3.20037774725275 0.270709234710749 0.548704792670656 GO:0016853 isomerase activity 5/364 180/18639 0.0277777777777778 1.42239010989011 0.276044686938245 0.548704792670656 GO:0004864 protein phosphatase inhibitor activity 2/364 53/18639 0.0377358490566038 1.93230354551109 0.277250939563576 0.548704792670656 GO:0005544 calcium-dependent phospholipid binding 2/364 53/18639 0.0377358490566038 1.93230354551109 0.277250939563576 0.548704792670656 GO:0034212 protein N-acetyltransferase activity 2/364 53/18639 0.0377358490566038 1.93230354551109 0.277250939563576 0.548704792670656 GO:0140296 general transcription initiation factor binding 2/364 53/18639 0.0377358490566038 1.93230354551109 0.277250939563576 0.548704792670656 GO:0016922 nuclear receptor binding 4/364 137/18639 0.0291970802919708 1.4950669768188 0.279508393506228 0.548704792670656 GO:0003925 G protein activity 2/364 54/18639 0.037037037037037 1.89652014652015 0.284510001976474 0.548704792670656 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/364 54/18639 0.037037037037037 1.89652014652015 0.284510001976474 0.548704792670656 GO:0050661 NADP binding 2/364 54/18639 0.037037037037037 1.89652014652015 0.284510001976474 0.548704792670656 GO:0051287 NAD binding 2/364 54/18639 0.037037037037037 1.89652014652015 0.284510001976474 0.548704792670656 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/364 17/18639 0.0588235294117647 3.01212023270847 0.284963750017912 0.548704792670656 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/364 17/18639 0.0588235294117647 3.01212023270847 0.284963750017912 0.548704792670656 GO:0004549 tRNA-specific ribonuclease activity 1/364 17/18639 0.0588235294117647 3.01212023270847 0.284963750017912 0.548704792670656 GO:0008484 sulfuric ester hydrolase activity 1/364 17/18639 0.0588235294117647 3.01212023270847 0.284963750017912 0.548704792670656 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/364 17/18639 0.0588235294117647 3.01212023270847 0.284963750017912 0.548704792670656 GO:0016018 cyclosporin A binding 1/364 17/18639 0.0588235294117647 3.01212023270847 0.284963750017912 0.548704792670656 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/364 17/18639 0.0588235294117647 3.01212023270847 0.284963750017912 0.548704792670656 GO:0030548 acetylcholine receptor regulator activity 1/364 17/18639 0.0588235294117647 3.01212023270847 0.284963750017912 0.548704792670656 GO:0031489 myosin V binding 1/364 17/18639 0.0588235294117647 3.01212023270847 0.284963750017912 0.548704792670656 GO:0036041 long-chain fatty acid binding 1/364 17/18639 0.0588235294117647 3.01212023270847 0.284963750017912 0.548704792670656 GO:0046965 nuclear retinoid X receptor binding 1/364 17/18639 0.0588235294117647 3.01212023270847 0.284963750017912 0.548704792670656 GO:0051787 misfolded protein binding 1/364 17/18639 0.0588235294117647 3.01212023270847 0.284963750017912 0.548704792670656 GO:0070403 NAD+ binding 1/364 17/18639 0.0588235294117647 3.01212023270847 0.284963750017912 0.548704792670656 GO:0030295 protein kinase activator activity 4/364 139/18639 0.0287769784172662 1.47355522175666 0.288223862564348 0.548704792670656 GO:0016407 acetyltransferase activity 3/364 96/18639 0.03125 1.60018887362637 0.289029258502155 0.548704792670656 GO:0000400 four-way junction DNA binding 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0008525 phosphatidylcholine transporter activity 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0015172 acidic amino acid transmembrane transporter activity 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0015373 monoatomic anion:sodium symporter activity 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0030228 lipoprotein particle receptor activity 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0031690 adrenergic receptor binding 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0032393 MHC class I receptor activity 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0070064 proline-rich region binding 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0070628 proteasome binding 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0099602 neurotransmitter receptor regulator activity 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:1901611 phosphatidylglycerol binding 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:1990381 ubiquitin-specific protease binding 1/364 18/18639 0.0555555555555556 2.84478021978022 0.29894040102175 0.548704792670656 GO:0019212 phosphatase inhibitor activity 2/364 56/18639 0.0357142857142857 1.82878728414443 0.299004350788647 0.548704792670656 GO:0019903 protein phosphatase binding 4/364 144/18639 0.0277777777777778 1.42239010989011 0.310166519974116 0.56178324679396 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/364 19/18639 0.0526315789473684 2.69505494505495 0.312644589520117 0.56178324679396 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/364 19/18639 0.0526315789473684 2.69505494505495 0.312644589520117 0.56178324679396 GO:0034987 immunoglobulin receptor binding 1/364 19/18639 0.0526315789473684 2.69505494505495 0.312644589520117 0.56178324679396 GO:0042577 lipid phosphatase activity 1/364 19/18639 0.0526315789473684 2.69505494505495 0.312644589520117 0.56178324679396 GO:0042800 histone H3K4 methyltransferase activity 1/364 19/18639 0.0526315789473684 2.69505494505495 0.312644589520117 0.56178324679396 GO:0043395 heparan sulfate proteoglycan binding 1/364 19/18639 0.0526315789473684 2.69505494505495 0.312644589520117 0.56178324679396 GO:0046624 sphingolipid transporter activity 1/364 19/18639 0.0526315789473684 2.69505494505495 0.312644589520117 0.56178324679396 GO:0004879 nuclear receptor activity 2/364 59/18639 0.0338983050847458 1.73579810020488 0.320650625368997 0.574672549362618 GO:0001972 retinoic acid binding 1/364 20/18639 0.05 2.5603021978022 0.32608161258213 0.581385820882867 GO:0016505 peptidase activator activity involved in apoptotic process 1/364 20/18639 0.05 2.5603021978022 0.32608161258213 0.581385820882867 GO:0098531 ligand-modulated transcription factor activity 2/364 60/18639 0.0333333333333333 1.70686813186813 0.327831768227297 0.581507711507987 GO:0019209 kinase activator activity 4/364 148/18639 0.027027027027027 1.38394713394713 0.327835506922619 0.581507711507987 GO:0001846 opsonin binding 1/364 21/18639 0.0476190476190476 2.4383830455259 0.339256664573112 0.594133591704001 GO:0036122 BMP binding 1/364 21/18639 0.0476190476190476 2.4383830455259 0.339256664573112 0.594133591704001 GO:0051428 peptide hormone receptor binding 1/364 21/18639 0.0476190476190476 2.4383830455259 0.339256664573112 0.594133591704001 GO:0008013 beta-catenin binding 3/364 106/18639 0.0283018867924528 1.44922765913332 0.342499312827391 0.594133591704001 GO:0005243 gap junction channel activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0015377 chloride:monoatomic cation symporter activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0032931 histone H3K56 acetyltransferase activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0043992 histone H3K9 acetyltransferase activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0043993 histone H3K18 acetyltransferase activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0043994 histone H3K23 acetyltransferase activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0043999 histone H2AK5 acetyltransferase activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0044012 histone H2AK9 acetyltransferase activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0044014 histone H2BK5 acetyltransferase activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0044015 histone H2BK12 acetyltransferase activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0044016 histone H3K4 acetyltransferase activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0044017 histone H3K27 acetyltransferase activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0044018 histone H3K36 acetyltransferase activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0046972 histone H4K16 acetyltransferase activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0070034 telomerase RNA binding 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0140908 histone H3K122 acetyltransferase activity 1/364 22/18639 0.0454545454545455 2.32754745254745 0.352174839140487 0.594133591704001 GO:0140297 DNA-binding transcription factor binding 11/364 488/18639 0.0225409836065574 1.15423459736984 0.356991710859254 0.600790928031428 GO:0003887 DNA-directed DNA polymerase activity 1/364 23/18639 0.0434782608695652 2.2263497372193 0.364841131161375 0.605145145435934 GO:0005283 amino acid:sodium symporter activity 1/364 23/18639 0.0434782608695652 2.2263497372193 0.364841131161375 0.605145145435934 GO:0008171 O-methyltransferase activity 1/364 23/18639 0.0434782608695652 2.2263497372193 0.364841131161375 0.605145145435934 GO:0031681 G-protein beta-subunit binding 1/364 23/18639 0.0434782608695652 2.2263497372193 0.364841131161375 0.605145145435934 GO:0044013 histone H2B acetyltransferase activity 1/364 23/18639 0.0434782608695652 2.2263497372193 0.364841131161375 0.605145145435934 GO:0099186 structural constituent of postsynapse 1/364 23/18639 0.0434782608695652 2.2263497372193 0.364841131161375 0.605145145435934 GO:0008235 metalloexopeptidase activity 2/364 66/18639 0.0303030303030303 1.5516983016983 0.370421731733654 0.609884175466424 GO:0031625 ubiquitin protein ligase binding 7/364 302/18639 0.0231788079470199 1.1868950585838 0.376943624307341 0.609884175466424 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/364 24/18639 0.0416666666666667 2.13358516483516 0.377260438652633 0.609884175466424 GO:0004622 lysophospholipase activity 1/364 24/18639 0.0416666666666667 2.13358516483516 0.377260438652633 0.609884175466424 GO:0005540 hyaluronic acid binding 1/364 24/18639 0.0416666666666667 2.13358516483516 0.377260438652633 0.609884175466424 GO:0030215 semaphorin receptor binding 1/364 24/18639 0.0416666666666667 2.13358516483516 0.377260438652633 0.609884175466424 GO:0043998 histone H2A acetyltransferase activity 1/364 24/18639 0.0416666666666667 2.13358516483516 0.377260438652633 0.609884175466424 GO:0048027 mRNA 5'-UTR binding 1/364 24/18639 0.0416666666666667 2.13358516483516 0.377260438652633 0.609884175466424 GO:0070300 phosphatidic acid binding 1/364 24/18639 0.0416666666666667 2.13358516483516 0.377260438652633 0.609884175466424 GO:0070840 dynein complex binding 1/364 24/18639 0.0416666666666667 2.13358516483516 0.377260438652633 0.609884175466424 GO:0008173 RNA methyltransferase activity 2/364 67/18639 0.0298507462686567 1.52853862555355 0.377421076701685 0.609884175466424 GO:0005548 phospholipid transporter activity 2/364 68/18639 0.0294117647058824 1.50606011635423 0.384387976054202 0.619690895975232 GO:0004709 MAP kinase kinase kinase activity 1/364 25/18639 0.04 2.04824175824176 0.389437564644061 0.623461530404645 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/364 25/18639 0.04 2.04824175824176 0.389437564644061 0.623461530404645 GO:0042974 nuclear retinoic acid receptor binding 1/364 25/18639 0.04 2.04824175824176 0.389437564644061 0.623461530404645 GO:0008094 ATP-dependent activity, acting on DNA 5/364 210/18639 0.0238095238095238 1.21919152276295 0.391180736328725 0.624802564969491 GO:0005160 transforming growth factor beta receptor binding 1/364 26/18639 0.0384615384615385 1.96946322907861 0.401377219015479 0.635207066790551 GO:0008143 poly(A) binding 1/364 26/18639 0.0384615384615385 1.96946322907861 0.401377219015479 0.635207066790551 GO:0070006 metalloaminopeptidase activity 1/364 26/18639 0.0384615384615385 1.96946322907861 0.401377219015479 0.635207066790551 GO:0097602 cullin family protein binding 1/364 26/18639 0.0384615384615385 1.96946322907861 0.401377219015479 0.635207066790551 GO:0008395 steroid hydroxylase activity 1/364 27/18639 0.037037037037037 1.89652014652015 0.413084020298365 0.649266455594241 GO:0015252 proton channel activity 1/364 27/18639 0.037037037037037 1.89652014652015 0.413084020298365 0.649266455594241 GO:0035255 ionotropic glutamate receptor binding 1/364 27/18639 0.037037037037037 1.89652014652015 0.413084020298365 0.649266455594241 GO:0004521 RNA endonuclease activity 2/364 73/18639 0.0273972602739726 1.40290531386422 0.418689019937013 0.656580508537588 GO:0015108 chloride transmembrane transporter activity 3/364 121/18639 0.0247933884297521 1.26957133775316 0.421830440579433 0.659793070350228 GO:0036408 histone H3K14 acetyltransferase activity 1/364 28/18639 0.0357142857142857 1.82878728414443 0.424562497442756 0.659793070350228 GO:0051019 mitogen-activated protein kinase binding 1/364 28/18639 0.0357142857142857 1.82878728414443 0.424562497442756 0.659793070350228 GO:0097718 disordered domain specific binding 1/364 28/18639 0.0357142857142857 1.82878728414443 0.424562497442756 0.659793070350228 GO:0003725 double-stranded RNA binding 2/364 75/18639 0.0266666666666667 1.36549450549451 0.432138202793652 0.668252873710075 GO:0019003 GDP binding 2/364 75/18639 0.0266666666666667 1.36549450549451 0.432138202793652 0.668252873710075 GO:0004181 metallocarboxypeptidase activity 1/364 29/18639 0.0344827586206897 1.76572565365669 0.435817091550049 0.668252873710075 GO:0004629 phospholipase C activity 1/364 29/18639 0.0344827586206897 1.76572565365669 0.435817091550049 0.668252873710075 GO:0005416 amino acid:monoatomic cation symporter activity 1/364 29/18639 0.0344827586206897 1.76572565365669 0.435817091550049 0.668252873710075 GO:0010484 histone H3 acetyltransferase activity 1/364 29/18639 0.0344827586206897 1.76572565365669 0.435817091550049 0.668252873710075 GO:0001965 G-protein alpha-subunit binding 1/364 30/18639 0.0333333333333333 1.70686813186813 0.446852157572391 0.676157870010854 GO:0016769 transferase activity, transferring nitrogenous groups 1/364 30/18639 0.0333333333333333 1.70686813186813 0.446852157572391 0.676157870010854 GO:0043995 histone H4K5 acetyltransferase activity 1/364 30/18639 0.0333333333333333 1.70686813186813 0.446852157572391 0.676157870010854 GO:0043996 histone H4K8 acetyltransferase activity 1/364 30/18639 0.0333333333333333 1.70686813186813 0.446852157572391 0.676157870010854 GO:0043997 histone H4K12 acetyltransferase activity 1/364 30/18639 0.0333333333333333 1.70686813186813 0.446852157572391 0.676157870010854 GO:0098918 structural constituent of synapse 1/364 30/18639 0.0333333333333333 1.70686813186813 0.446852157572391 0.676157870010854 GO:0004519 endonuclease activity 3/364 127/18639 0.0236220472440945 1.20959158951285 0.452719194207803 0.682891802069895 GO:0008017 microtubule binding 6/364 276/18639 0.0217391304347826 1.11317486860965 0.453281804852191 0.682891802069895 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/364 31/18639 0.032258064516129 1.65180786954981 0.457671965979272 0.68629815240155 GO:0031490 chromatin DNA binding 3/364 128/18639 0.0234375 1.20014165521978 0.457802715244574 0.68629815240155 GO:0046332 SMAD binding 2/364 79/18639 0.0253164556962025 1.29635554319099 0.458526736604514 0.68629815240155 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 5/364 229/18639 0.0218340611353712 1.11803589423677 0.464020552792706 0.691892261307198 GO:0030515 snoRNA binding 1/364 32/18639 0.03125 1.60018887362637 0.468280704391973 0.691892261307198 GO:0031369 translation initiation factor binding 1/364 32/18639 0.03125 1.60018887362637 0.468280704391973 0.691892261307198 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/364 32/18639 0.03125 1.60018887362637 0.468280704391973 0.691892261307198 GO:0043425 bHLH transcription factor binding 1/364 32/18639 0.03125 1.60018887362637 0.468280704391973 0.691892261307198 GO:0070717 poly-purine tract binding 1/364 32/18639 0.03125 1.60018887362637 0.468280704391973 0.691892261307198 GO:0019956 chemokine binding 1/364 33/18639 0.0303030303030303 1.5516983016983 0.478682479186476 0.704245012022747 GO:0140416 transcription regulator inhibitor activity 1/364 33/18639 0.0303030303030303 1.5516983016983 0.478682479186476 0.704245012022747 GO:0035091 phosphatidylinositol binding 6/364 284/18639 0.0211267605633803 1.08181783005727 0.480601456283023 0.705563840075076 GO:0005254 chloride channel activity 2/364 83/18639 0.0240963855421687 1.23388057725407 0.484191627596314 0.706550762966003 GO:0008135 translation factor activity, RNA binding 2/364 83/18639 0.0240963855421687 1.23388057725407 0.484191627596314 0.706550762966003 GO:0140097 catalytic activity, acting on DNA 7/364 336/18639 0.0208333333333333 1.06679258241758 0.484820608572491 0.706550762966003 GO:0015020 glucuronosyltransferase activity 1/364 34/18639 0.0294117647058824 1.50606011635423 0.488881317065446 0.706550762966003 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/364 34/18639 0.0294117647058824 1.50606011635423 0.488881317065446 0.706550762966003 GO:0019825 oxygen binding 1/364 34/18639 0.0294117647058824 1.50606011635423 0.488881317065446 0.706550762966003 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/364 34/18639 0.0294117647058824 1.50606011635423 0.488881317065446 0.706550762966003 GO:0004527 exonuclease activity 2/364 84/18639 0.0238095238095238 1.21919152276295 0.490489587624226 0.706550762966003 GO:0180051 translation factor activity 2/364 84/18639 0.0238095238095238 1.21919152276295 0.490489587624226 0.706550762966003 GO:0005154 epidermal growth factor receptor binding 1/364 35/18639 0.0285714285714286 1.46302982731554 0.498881166599882 0.709748463822513 GO:0005343 organic acid:sodium symporter activity 1/364 35/18639 0.0285714285714286 1.46302982731554 0.498881166599882 0.709748463822513 GO:0010485 histone H4 acetyltransferase activity 1/364 35/18639 0.0285714285714286 1.46302982731554 0.498881166599882 0.709748463822513 GO:0016229 steroid dehydrogenase activity 1/364 35/18639 0.0285714285714286 1.46302982731554 0.498881166599882 0.709748463822513 GO:0034061 DNA polymerase activity 1/364 35/18639 0.0285714285714286 1.46302982731554 0.498881166599882 0.709748463822513 GO:0061631 ubiquitin conjugating enzyme activity 1/364 35/18639 0.0285714285714286 1.46302982731554 0.498881166599882 0.709748463822513 GO:0003712 transcription coregulator activity 10/364 495/18639 0.0202020202020202 1.03446553446553 0.501735946468559 0.711123586211356 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/364 86/18639 0.0232558139534884 1.19083823153591 0.502939579813249 0.711123586211356 GO:0050660 flavin adenine dinucleotide binding 2/364 86/18639 0.0232558139534884 1.19083823153591 0.502939579813249 0.711123586211356 GO:0004190 aspartic-type endopeptidase activity 1/364 36/18639 0.0277777777777778 1.42239010989011 0.508685899741016 0.713400956953864 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/364 36/18639 0.0277777777777778 1.42239010989011 0.508685899741016 0.713400956953864 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/364 36/18639 0.0277777777777778 1.42239010989011 0.508685899741016 0.713400956953864 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/364 36/18639 0.0277777777777778 1.42239010989011 0.508685899741016 0.713400956953864 GO:0019902 phosphatase binding 4/364 190/18639 0.0210526315789474 1.07802197802198 0.51024095170223 0.714130338082229 GO:0022829 wide pore channel activity 1/364 37/18639 0.027027027027027 1.38394713394713 0.518299313303036 0.721021222135272 GO:0030280 structural constituent of skin epidermis 1/364 37/18639 0.027027027027027 1.38394713394713 0.518299313303036 0.721021222135272 GO:0070001 aspartic-type peptidase activity 1/364 37/18639 0.027027027027027 1.38394713394713 0.518299313303036 0.721021222135272 GO:0020037 heme binding 3/364 142/18639 0.0211267605633803 1.08181783005727 0.526643266318184 0.725359243003723 GO:0000146 microfilament motor activity 1/364 38/18639 0.0263157894736842 1.34752747252747 0.527725130417201 0.725359243003723 GO:0005109 frizzled binding 1/364 38/18639 0.0263157894736842 1.34752747252747 0.527725130417201 0.725359243003723 GO:0042162 telomeric DNA binding 1/364 38/18639 0.0263157894736842 1.34752747252747 0.527725130417201 0.725359243003723 GO:0042887 amide transmembrane transporter activity 1/364 38/18639 0.0263157894736842 1.34752747252747 0.527725130417201 0.725359243003723 GO:0043531 ADP binding 1/364 38/18639 0.0263157894736842 1.34752747252747 0.527725130417201 0.725359243003723 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/364 91/18639 0.021978021978022 1.12540755947349 0.533192011670355 0.73141647724164 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/364 39/18639 0.0256410256410256 1.31297548605241 0.536967001957878 0.735133395537572 GO:0008194 UDP-glycosyltransferase activity 3/364 145/18639 0.0206896551724138 1.05943539219401 0.54076272973299 0.738863927753986 GO:0030331 nuclear estrogen receptor binding 1/364 40/18639 0.025 1.2801510989011 0.546028507941068 0.740195816265888 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/364 40/18639 0.025 1.2801510989011 0.546028507941068 0.740195816265888 GO:0071855 neuropeptide receptor binding 1/364 40/18639 0.025 1.2801510989011 0.546028507941068 0.740195816265888 GO:0071949 FAD binding 1/364 40/18639 0.025 1.2801510989011 0.546028507941068 0.740195816265888 GO:0001530 lipopolysaccharide binding 1/364 41/18639 0.024390243902439 1.24892790136693 0.554913158895929 0.743475882792604 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/364 41/18639 0.024390243902439 1.24892790136693 0.554913158895929 0.743475882792604 GO:0008227 G protein-coupled amine receptor activity 1/364 41/18639 0.024390243902439 1.24892790136693 0.554913158895929 0.743475882792604 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/364 41/18639 0.024390243902439 1.24892790136693 0.554913158895929 0.743475882792604 GO:0017080 sodium channel regulator activity 1/364 41/18639 0.024390243902439 1.24892790136693 0.554913158895929 0.743475882792604 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/364 41/18639 0.024390243902439 1.24892790136693 0.554913158895929 0.743475882792604 GO:0008509 monoatomic anion transmembrane transporter activity 3/364 149/18639 0.0201342281879195 1.03099417361162 0.559207039075154 0.743759465715317 GO:0004402 histone acetyltransferase activity 1/364 42/18639 0.0238095238095238 1.21919152276295 0.563624397209827 0.743759465715317 GO:0016859 cis-trans isomerase activity 1/364 42/18639 0.0238095238095238 1.21919152276295 0.563624397209827 0.743759465715317 GO:0019894 kinesin binding 1/364 42/18639 0.0238095238095238 1.21919152276295 0.563624397209827 0.743759465715317 GO:0031492 nucleosomal DNA binding 1/364 42/18639 0.0238095238095238 1.21919152276295 0.563624397209827 0.743759465715317 GO:0035198 miRNA binding 1/364 42/18639 0.0238095238095238 1.21919152276295 0.563624397209827 0.743759465715317 GO:0048487 beta-tubulin binding 1/364 42/18639 0.0238095238095238 1.21919152276295 0.563624397209827 0.743759465715317 GO:0019842 vitamin binding 3/364 150/18639 0.02 1.02412087912088 0.563748116766827 0.743759465715317 GO:0016887 ATP hydrolysis activity 8/364 417/18639 0.0191846522781775 0.982370147837774 0.570201596292668 0.748472995122595 GO:0008200 ion channel inhibitor activity 1/364 43/18639 0.0232558139534884 1.19083823153591 0.572165598447426 0.748472995122595 GO:0008375 acetylglucosaminyltransferase activity 1/364 43/18639 0.0232558139534884 1.19083823153591 0.572165598447426 0.748472995122595 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/364 43/18639 0.0232558139534884 1.19083823153591 0.572165598447426 0.748472995122595 GO:0046906 tetrapyrrole binding 3/364 152/18639 0.0197368421052632 1.0106456043956 0.572744552789464 0.748472995122595 GO:0016248 channel inhibitor activity 1/364 44/18639 0.0227272727272727 1.16377372627373 0.580540072644304 0.755089656593243 GO:0043014 alpha-tubulin binding 1/364 44/18639 0.0227272727272727 1.16377372627373 0.580540072644304 0.755089656593243 GO:0005506 iron ion binding 3/364 154/18639 0.0194805194805195 0.997520336806051 0.581625240526201 0.755089656593243 GO:0046982 protein heterodimerization activity 7/364 369/18639 0.018970189701897 0.971388367729831 0.583986565293149 0.755089656593243 GO:0043130 ubiquitin binding 2/364 100/18639 0.02 1.02412087912088 0.584399976713685 0.755089656593243 GO:0004518 nuclease activity 4/364 209/18639 0.0191387559808612 0.98001998001998 0.585496679107542 0.755089656593243 GO:0004386 helicase activity 3/364 155/18639 0.0193548387096774 0.991084721729883 0.586021676693383 0.755089656593243 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/364 45/18639 0.0222222222222222 1.13791208791209 0.588751065575601 0.755089656593243 GO:0046915 transition metal ion transmembrane transporter activity 1/364 45/18639 0.0222222222222222 1.13791208791209 0.588751065575601 0.755089656593243 GO:0141110 transporter inhibitor activity 1/364 45/18639 0.0222222222222222 1.13791208791209 0.588751065575601 0.755089656593243 GO:0015171 amino acid transmembrane transporter activity 2/364 102/18639 0.0196078431372549 1.00404007756949 0.595202100461299 0.761947030275132 GO:0030276 clathrin binding 1/364 46/18639 0.0217391304347826 1.11317486860965 0.596801760000172 0.762580026666887 GO:0005253 monoatomic anion channel activity 2/364 103/18639 0.0194174757281553 0.994292115651339 0.600523993515468 0.765917847552075 GO:0140938 histone H3 methyltransferase activity 1/364 47/18639 0.0212765957446809 1.08949029693711 0.604695276880715 0.769815020383199 GO:0099106 ion channel regulator activity 3/364 160/18639 0.01875 0.960113324175824 0.607557867028362 0.772034858654824 GO:0005525 GTP binding 7/364 378/18639 0.0185185185185185 0.948260073260073 0.609398669777673 0.77254099970829 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/364 48/18639 0.0208333333333333 1.06679258241758 0.61243467658034 0.77254099970829 GO:0038187 pattern recognition receptor activity 1/364 48/18639 0.0208333333333333 1.06679258241758 0.61243467658034 0.77254099970829 GO:0140693 molecular condensate scaffold activity 1/364 48/18639 0.0208333333333333 1.06679258241758 0.61243467658034 0.77254099970829 GO:0035254 glutamate receptor binding 1/364 49/18639 0.0204081632653061 1.04502130522539 0.620022960036031 0.780685843840988 GO:0015103 inorganic anion transmembrane transporter activity 3/364 165/18639 0.0181818181818182 0.931018981018981 0.628338038234897 0.788588452484958 GO:0015631 tubulin binding 7/364 385/18639 0.0181818181818182 0.931018981018981 0.628584998357575 0.788588452484958 GO:0004620 phospholipase activity 2/364 109/18639 0.018348623853211 0.93956043956044 0.63134858180233 0.790618006249741 GO:0140098 catalytic activity, acting on RNA 7/364 387/18639 0.0180878552971576 0.926207513416816 0.633969519754341 0.792461899692927 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/364 167/18639 0.0179640718562874 0.919869053102586 0.636435443033927 0.794105706498028 GO:0016247 channel regulator activity 3/364 168/18639 0.0178571428571429 0.914393642072214 0.640437841791026 0.797172087259629 GO:1902936 phosphatidylinositol bisphosphate binding 2/364 111/18639 0.018018018018018 0.922631422631423 0.641203635404484 0.797172087259629 GO:0141108 transporter regulator activity 3/364 170/18639 0.0176470588235294 0.90363606981254 0.648349760587619 0.802431585141344 GO:0005246 calcium channel regulator activity 1/364 53/18639 0.0188679245283019 0.966151772755546 0.648922934070826 0.802431585141344 GO:0051018 protein kinase A binding 1/364 53/18639 0.0188679245283019 0.966151772755546 0.648922934070826 0.802431585141344 GO:0140463 chromatin-protein adaptor activity 1/364 54/18639 0.0185185185185185 0.948260073260073 0.655798649770719 0.809483127623965 GO:0019001 guanyl nucleotide binding 7/364 400/18639 0.0175 0.896105769230769 0.667868113392263 0.82144206460011 GO:0032561 guanyl ribonucleotide binding 7/364 400/18639 0.0175 0.896105769230769 0.667868113392263 0.82144206460011 GO:0008408 3'-5' exonuclease activity 1/364 58/18639 0.0172413793103448 0.882862826828344 0.681984462499215 0.835578654790009 GO:0061980 regulatory RNA binding 1/364 58/18639 0.0172413793103448 0.882862826828344 0.681984462499215 0.835578654790009 GO:0032182 ubiquitin-like protein binding 2/364 120/18639 0.0166666666666667 0.853434065934066 0.682994726524008 0.835578654790009 GO:0004540 RNA nuclease activity 2/364 121/18639 0.0165289256198347 0.846380891835437 0.687384042254168 0.836035045435844 GO:0015459 potassium channel regulator activity 1/364 59/18639 0.0169491525423729 0.86789905010244 0.688214356242839 0.836035045435844 GO:0031593 polyubiquitin modification-dependent protein binding 1/364 59/18639 0.0169491525423729 0.86789905010244 0.688214356242839 0.836035045435844 GO:0070888 E-box binding 1/364 59/18639 0.0169491525423729 0.86789905010244 0.688214356242839 0.836035045435844 GO:0008528 G protein-coupled peptide receptor activity 2/364 122/18639 0.0163934426229508 0.839443343541704 0.691723415829434 0.836095200058471 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/364 122/18639 0.0163934426229508 0.839443343541704 0.691723415829434 0.836095200058471 GO:0141003 histone H2AX kinase activity 6/364 354/18639 0.0169491525423729 0.86789905010244 0.692940589962652 0.836095200058471 GO:0001098 basal transcription machinery binding 1/364 60/18639 0.0166666666666667 0.853434065934066 0.69432253570073 0.836095200058471 GO:0001099 basal RNA polymerase II transcription machinery binding 1/364 60/18639 0.0166666666666667 0.853434065934066 0.69432253570073 0.836095200058471 GO:0015026 coreceptor activity 1/364 61/18639 0.0163934426229508 0.839443343541704 0.700311372398342 0.840760322402768 GO:0140996 histone H3 kinase activity 6/364 357/18639 0.0168067226890756 0.860605780773848 0.700633602002307 0.840760322402768 GO:1901981 phosphatidylinositol phosphate binding 3/364 185/18639 0.0162162162162162 0.83036828036828 0.703729931331477 0.843009813574165 GO:0015179 L-amino acid transmembrane transporter activity 1/364 62/18639 0.0161290322580645 0.825903934774903 0.706183191778631 0.844482499700615 GO:0035173 histone kinase activity 6/364 360/18639 0.0166666666666667 0.853434065934066 0.708196829400197 0.845425280771862 GO:1901682 sulfur compound transmembrane transporter activity 1/364 63/18639 0.0158730158730159 0.812794348508634 0.711940274095074 0.84842623337755 GO:0001653 peptide receptor activity 2/364 128/18639 0.015625 0.800094436813187 0.716726596517647 0.852657502753752 GO:0016298 lipase activity 2/364 130/18639 0.0153846153846154 0.787785291631446 0.724674636101108 0.859150341769355 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/364 130/18639 0.0153846153846154 0.787785291631446 0.724674636101108 0.859150341769355 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/364 132/18639 0.0151515151515152 0.775849150849151 0.732433737573131 0.865584718401624 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/364 67/18639 0.0149253731343284 0.764269312776776 0.733865304731812 0.865584718401624 GO:0042054 histone methyltransferase activity 1/364 67/18639 0.0149253731343284 0.764269312776776 0.733865304731812 0.865584718401624 GO:1990841 promoter-specific chromatin binding 1/364 68/18639 0.0147058823529412 0.753030058177117 0.739081384264313 0.870249411505762 GO:0016758 hexosyltransferase activity 3/364 197/18639 0.0152284263959391 0.779787471411837 0.743056910463484 0.871807979514699 GO:0002039 p53 binding 1/364 69/18639 0.0144927536231884 0.742116579073101 0.744195507150953 0.871807979514699 GO:0016279 protein-lysine N-methyltransferase activity 1/364 69/18639 0.0144927536231884 0.742116579073101 0.744195507150953 0.871807979514699 GO:0044325 transmembrane transporter binding 2/364 136/18639 0.0147058823529412 0.753030058177117 0.747395919841612 0.873234233160983 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/364 70/18639 0.0142857142857143 0.731514913657771 0.74920966091493 0.873234233160983 GO:0016278 lysine N-methyltransferase activity 1/364 70/18639 0.0142857142857143 0.731514913657771 0.74920966091493 0.873234233160983 GO:0043539 protein serine/threonine kinase activator activity 1/364 73/18639 0.0136986301369863 0.701452656932109 0.76367160759159 0.88600286953392 GO:0003714 transcription corepressor activity 3/364 204/18639 0.0147058823529412 0.753030058177117 0.764016967206786 0.88600286953392 GO:0008168 methyltransferase activity 3/364 204/18639 0.0147058823529412 0.753030058177117 0.764016967206786 0.88600286953392 GO:0031491 nucleosome binding 1/364 74/18639 0.0135135135135135 0.691973566973567 0.768304998458587 0.887990701736055 GO:0035064 methylated histone binding 1/364 74/18639 0.0135135135135135 0.691973566973567 0.768304998458587 0.887990701736055 GO:0140034 methylation-dependent protein binding 1/364 76/18639 0.0131578947368421 0.673763736263736 0.777301757837842 0.896886643659049 GO:0051540 metal cluster binding 1/364 77/18639 0.012987012987013 0.665013557870701 0.781668625270209 0.898944205839216 GO:0015293 symporter activity 2/364 146/18639 0.0136986301369863 0.701452656932109 0.781690613773231 0.898944205839216 GO:0015370 solute:sodium symporter activity 1/364 79/18639 0.0126582278481013 0.648177771595493 0.790147829233326 0.905651166397001 GO:0016835 carbon-oxygen lyase activity 1/364 79/18639 0.0126582278481013 0.648177771595493 0.790147829233326 0.905651166397001 GO:0016741 transferase activity, transferring one-carbon groups 3/364 215/18639 0.013953488372093 0.714502938921544 0.794132795240111 0.908709168682714 GO:0015101 organic cation transmembrane transporter activity 1/364 81/18639 0.0123456790123457 0.632173382173382 0.798298601012704 0.911963633607228 GO:0008081 phosphoric diester hydrolase activity 1/364 87/18639 0.0114942528735632 0.588575217885563 0.820904775356729 0.936238504125856 GO:0052689 carboxylic ester hydrolase activity 1/364 92/18639 0.0108695652173913 0.556587434304826 0.837800179292731 0.953930897214496 GO:0008276 protein methyltransferase activity 1/364 95/18639 0.0105263157894737 0.539010989010989 0.847164386816638 0.963003998193542 GO:0140030 modification-dependent protein binding 2/364 173/18639 0.0115606936416185 0.591977386775075 0.854653438474429 0.968250275722953 GO:0008170 N-methyltransferase activity 1/364 98/18639 0.0102040816326531 0.522510652612693 0.855989374189857 0.968250275722953 GO:0030527 structural constituent of chromatin 1/364 98/18639 0.0102040816326531 0.522510652612693 0.855989374189857 0.968250275722953 GO:0042393 histone binding 3/364 247/18639 0.0121457489878543 0.621935756551141 0.864020936084182 0.975735590667898 GO:0000149 SNARE binding 1/364 106/18639 0.00943396226415094 0.483075886377773 0.877116428055724 0.987292553602691 GO:0004497 monooxygenase activity 1/364 106/18639 0.00943396226415094 0.483075886377773 0.877116428055724 0.987292553602691 GO:0046943 carboxylic acid transmembrane transporter activity 2/364 188/18639 0.0106382978723404 0.544745148468553 0.884853544216959 0.994379390080948 GO:0005342 organic acid transmembrane transporter activity 2/364 189/18639 0.0105820105820106 0.541862899005756 0.886645304944006 0.99477278115669 GO:0003924 GTPase activity 4/364 331/18639 0.0120845921450151 0.618804156568507 0.890184628201929 0.996313673342872 GO:0043022 ribosome binding 1/364 112/18639 0.00892857142857143 0.457196821036107 0.890906574568916 0.996313673342872 GO:0016757 glycosyltransferase activity 3/364 267/18639 0.0112359550561798 0.575348808494876 0.896288445635964 0.999145881346557 GO:0101005 deubiquitinase activity 1/364 115/18639 0.00869565217391304 0.44526994744386 0.89721147992606 0.999145881346557 GO:0008514 organic anion transmembrane transporter activity 3/364 269/18639 0.0111524163568773 0.571071122186364 0.899105010551112 0.999145881346557 GO:0015294 solute:monoatomic cation symporter activity 1/364 116/18639 0.00862068965517241 0.441431413414172 0.899231293211901 0.999145881346557 GO:1990782 protein tyrosine kinase binding 1/364 117/18639 0.00854700854700855 0.437658495350803 0.90121152369675 0.999396097634508 GO:0016829 lyase activity 2/364 200/18639 0.01 0.51206043956044 0.904720435500876 0.999396097634508 GO:0003697 single-stranded DNA binding 1/364 121/18639 0.00826446280991736 0.423190445917719 0.908751865578617 0.999396097634508 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/364 122/18639 0.00819672131147541 0.419721671770852 0.910545489130264 0.999396097634508 GO:0019783 ubiquitin-like protein peptidase activity 1/364 127/18639 0.0078740157480315 0.403197196504283 0.918999733622717 0.999396097634508 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/364 128/18639 0.0078125 0.400047218406593 0.920592435489686 0.999396097634508 GO:0005262 calcium channel activity 1/364 131/18639 0.00763358778625954 0.390885831725526 0.925185575522775 0.999396097634508 GO:0031072 heat shock protein binding 1/364 131/18639 0.00763358778625954 0.390885831725526 0.925185575522775 0.999396097634508 GO:0015297 antiporter activity 1/364 135/18639 0.00740740740740741 0.379304029304029 0.930900214368594 0.999396097634508 GO:0016779 nucleotidyltransferase activity 1/364 136/18639 0.00735294117647059 0.376515029088559 0.932259505439164 0.999396097634508 GO:0140101 catalytic activity, acting on a tRNA 1/364 139/18639 0.00719424460431655 0.368388805439165 0.936179452467252 0.999396097634508 GO:0140767 enzyme-substrate adaptor activity 1/364 139/18639 0.00719424460431655 0.368388805439165 0.936179452467252 0.999396097634508 GO:0005085 guanyl-nucleotide exchange factor activity 2/364 230/18639 0.00869565217391304 0.44526994744386 0.941265085200746 0.999396097634508 GO:0015085 calcium ion transmembrane transporter activity 1/364 147/18639 0.00680272108843537 0.348340435075129 0.945561574058648 0.999396097634508 GO:0003774 cytoskeletal motor activity 1/364 153/18639 0.0065359477124183 0.334680025856496 0.951683604144929 0.999396097634508 GO:0015081 sodium ion transmembrane transporter activity 1/364 164/18639 0.00609756097560976 0.312231975341731 0.961179286052147 0.999396097634508 GO:0016874 ligase activity 1/364 167/18639 0.00598802395209581 0.306623017700862 0.963429066074238 0.999396097634508 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/364 268/18639 0.00746268656716418 0.382134656388388 0.968732309233672 0.999396097634508 GO:0043021 ribonucleoprotein complex binding 1/364 177/18639 0.00564971751412429 0.28929968336748 0.970030435255473 0.999396097634508 GO:0005096 GTPase activator activity 2/364 271/18639 0.00738007380073801 0.377904383439439 0.970271984427384 0.999396097634508 GO:0016791 phosphatase activity 2/364 273/18639 0.00732600732600733 0.375135853157831 0.971257632479019 0.999396097634508 GO:0045182 translation regulator activity 3/364 356/18639 0.00842696629213483 0.431511606371157 0.971458146139569 0.999396097634508 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/364 181/18639 0.00552486187845304 0.282906320199138 0.972325171038484 0.999396097634508 GO:0001217 DNA-binding transcription repressor activity 2/364 278/18639 0.00719424460431655 0.368388805439165 0.973586041474823 0.999396097634508 GO:0042578 phosphoric ester hydrolase activity 3/364 363/18639 0.00826446280991736 0.423190445917719 0.97433730665202 0.999396097634508 GO:0022834 ligand-gated channel activity 1/364 188/18639 0.00531914893617021 0.272372574234276 0.975927310538562 0.999396097634508 GO:0005216 monoatomic ion channel activity 4/364 448/18639 0.00892857142857143 0.457196821036107 0.976852288013178 0.999396097634508 GO:0015291 secondary active transmembrane transporter activity 2/364 287/18639 0.00696864111498258 0.356836543247693 0.977326876167853 0.999396097634508 GO:0030695 GTPase regulator activity 4/364 489/18639 0.0081799591002045 0.418863345243713 0.987168832124391 0.999396097634508 GO:0060589 nucleoside-triphosphatase regulator activity 4/364 490/18639 0.00816326530612245 0.418008522090155 0.987355172733137 0.999396097634508 GO:0016755 aminoacyltransferase activity 4/364 496/18639 0.00806451612903226 0.412951967387451 0.988420365203769 0.999396097634508 GO:0000287 magnesium ion binding 1/364 230/18639 0.00434782608695652 0.22263497372193 0.989584632662507 0.999396097634508 GO:0005261 monoatomic cation channel activity 2/364 341/18639 0.00586510263929619 0.30032870355451 0.99107131802236 0.999396097634508 GO:0004674 protein serine/threonine kinase activity 3/364 433/18639 0.0069284064665127 0.354776286069589 0.991405474553212 0.999396097634508 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/364 243/18639 0.00411522633744856 0.210724460724461 0.991966877150545 0.999396097634508 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0004711 ribosomal protein S6 kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0035175 histone H3S10 kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0035979 histone H2AXS139 kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0044022 histone H3S28 kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0044023 histone H4S1 kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0044024 histone H2AS1 kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0044025 histone H2BS14 kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0072354 histone H3T3 kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0072371 histone H2AS121 kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0140823 histone H2BS36 kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0140855 histone H3S57 kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0140995 histone H2A kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0140997 histone H4 kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0140998 histone H2B kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:1990244 histone H2AT120 kinase activity 1/364 245/18639 0.00408163265306122 0.209004261045077 0.992281641838561 0.999396097634508 GO:0004677 DNA-dependent protein kinase activity 1/364 246/18639 0.0040650406504065 0.208154650227821 0.992434380904058 0.999396097634508 GO:0140857 histone H3T45 kinase activity 1/364 246/18639 0.0040650406504065 0.208154650227821 0.992434380904058 0.999396097634508 GO:0035402 histone H3T11 kinase activity 1/364 247/18639 0.00404858299595142 0.20731191885038 0.992584105546636 0.999396097634508 GO:0035403 histone H3T6 kinase activity 1/364 247/18639 0.00404858299595142 0.20731191885038 0.992584105546636 0.999396097634508 GO:0004679 AMP-activated protein kinase activity 1/364 248/18639 0.00403225806451613 0.206475983693726 0.992730875097583 0.999396097634508 GO:0004842 ubiquitin-protein transferase activity 3/364 449/18639 0.0066815144766147 0.342133923982476 0.993353088172375 0.999396097634508 GO:0046873 metal ion transmembrane transporter activity 3/364 450/18639 0.00666666666666667 0.341373626373626 0.993459493991739 0.999396097634508 GO:0003730 mRNA 3'-UTR binding 1/364 262/18639 0.00381679389312977 0.195442915862763 0.994505953641184 0.999396097634508 GO:0019787 ubiquitin-like protein transferase activity 3/364 479/18639 0.00626304801670146 0.320705912042029 0.99591928019054 0.999396097634508 GO:0031267 small GTPase binding 1/364 283/18639 0.00353356890459364 0.180940084650332 0.996391455504458 0.999396097634508 GO:0051020 GTPase binding 1/364 315/18639 0.00317460317460317 0.162558869701727 0.998100064038329 0.999396097634508 GO:0022836 gated channel activity 1/364 318/18639 0.00314465408805031 0.161025295459258 0.998211060433568 0.999396097634508 GO:0061630 ubiquitin protein ligase activity 1/364 353/18639 0.0028328611898017 0.145059614606357 0.999114332556625 0.999396097634508 GO:0106310 protein serine kinase activity 1/364 361/18639 0.00277008310249307 0.141844997108155 0.999245951585865 0.999396097634508 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 2/364 484/18639 0.00413223140495868 0.211595222958859 0.999313366468783 0.999396097634508 GO:0061659 ubiquitin-like protein ligase activity 1/364 372/18639 0.00268817204301075 0.137650655795817 0.999395668081586 0.999396097634508 GO:0001216 DNA-binding transcription activator activity 2/364 491/18639 0.00407331975560081 0.208578590452318 0.999396097634508 0.999396097634508